ライフサイエンスコーパス: fragilis

1 echinoid, the sea urchin, Strongylocentrotus fragilis.

2 le for lipopolysaccharide biosynthesis in B. fragilis.

3 lori, Clostridium difficile, and Bacteroides fragilis.

4 eted by enterotoxigenic (ETBF) strains of B. fragilis.

5 dentified 1021 candidate glycoproteins of B. fragilis.

6 inal recolonization with either strain of B. fragilis.

7 a including Escherichia coli and Bacteroides fragilis.

8 irines were isolated from the sponge Dysidea fragilis.

9 RprY, a response regulator from Bacteroides fragilis.

10 bdominal abscess formation in response to B. fragilis.

11 s response important for aerotolerance of B. fragilis.

12 known virulence factor of enterotoxigenic B. fragilis.

13 ction of selective metabolic responses in B. fragilis.

14 metallo-beta-lactamase CcrA from Bacteroides fragilis.

15 those of Bacteroides thetaiotaomicron and B. fragilis.

16 e within-microbiome evolution of Bacteroides fragilis.

17 ated with the choA orthologue in Bacteroides fragilis.

18 function, associated with an increase in B. fragilis.

19 naerobic Gram-negative bacterium Bacteroides fragilis.

20 transmission of the trichomonad Dientamoeba fragilis.

21 We used 432 sequences (137 of O. fragilis, 215 of Ophiothrix sp. II, and 80 of Ophiothrix

22 ifunctional enzyme isolated from Bacteroides fragilis 9343, which converts l-fucose into GDP-fucose v

23 the ubiquitous gut microorganism Bacteroides fragilis, a bacterial polysaccharide (PSA) directs the c

24 s commensal anaerobes, including Bacteroides fragilis, a common and immunologically important commens

25 type of phase-variable system of Bacteroides fragilis, a Type I restriction modification system (R-M)

26 lation and survival in vivo Consequently, B. fragilis acquires essential heme from host tissues durin

27 that the prominent gut commensal Bacteroides fragilis activates the TLR pathway to establish host-mic

28 uced by the intestinal commensal Bacteroides fragilis, activates CD4+ T cells, resulting in a Th1 res

29 lectively, these results demonstrate that B. fragilis adapts within individual microbiomes, pointing

30 We studied the dissemination of B. fragilis after acute peritonitis and characterized the i

31 ingle gene, oxe (i.e., oxygen enabled) in B. fragilis allows for growth in concentrations as high as

32 ferrin as a model, it has been shown that B. fragilis alone can rapidly and efficiently deglycosylate

33 distribution and colonization of labeled B. fragilis along the intestine, as well as niche competiti

34 uired for GALT development, we introduced B. fragilis along with stress-response mutants of B. subtil

35 apsule biogenesis in E. coli and Bacteroides fragilis also depends on processive antiterminators but

36 as increased in YAMC cells incubated with B. fragilis, an effect mediated by lipopolysaccharide and o

37 documenting the pathogenicity of Dientamoeba fragilis, an intestinal protozoan common in children.

38 e obligately anaerobic bacterium Bacteroides fragilis, an opportunistic pathogen and inhabitant of th

39 ative promoters, resulting in 188 hits in B. fragilis and 109 hits in F. johnsoniae.

40 e were untreated or treated with Bacteroides fragilis and antibiotic-mediated depletion of intestinal

41 e were untreated or treated with Bacteroides fragilis and antibiotic-mediated depletion of intestinal

42 The combination of Bacteroides fragilis and Bacillus subtilis consistently promoted GAL

43 to global public health such as Dientamoeba fragilis and Blastocystis hominis and how they too might

44 When intestinal integrity is disrupted, B. fragilis and colonic contents escape into the peritoneum

45 osylation is central to the physiology of B. fragilis and is necessary for the organism to competitiv

46 pports lipopolysaccharide biosynthesis in B. fragilis and is subject to feedback regulation by CMP-Kd

47 zinc metallo-beta-lactamase from Bacteroides fragilis and its complex with a biphenyl tetrazole inhib

48 Using Bacteroides fragilis and its OM-associated polysaccharide A, we dete

49 xistence of two distinct species, Ophiothrix fragilis and Ophiothrix sp. II.

50 e considered human-specific; by contrast, D. fragilis and P. hominis have been isolated from domestic

51 O-glycosylation systems, that of Bacteroides fragilis and related species is unique in that extracyto

52 ures of various bacteria such as Bacteroides fragilis and Salmonella abortus are observed for CD14(+/

53 e of two distinct subfamilies of GH110 in B. fragilis and thetaiotaomicron strains.

54 h the promoter regions of nqrA genes from B. fragilis and Vibrio cholerae.

55 mM, while those of Bacteroides pyogenes, B. fragilis, and Akkermansia muciniphila were greater in th

56 ffects on Staphylococcus aureus, Bacteroides fragilis, and Candida albicans are investigated.

57 res containing Escherichia coli, Bacteroides fragilis, and Clostridium perfringens.

58 erium nucleatum, enterotoxigenic Bacteroides fragilis, and colibactin-producing Escherichia coli.

59 Ophiothrix fragilis appeared genetically isolated between the Atlan

60 ons of GA3 loci, GA3 T6SSs of the species B. fragilis are likely the source of numerous novel effecto

61 The ccf genes of B. fragilis are upregulated during gut colonization, prefer

62 half of the extracytoplasmic proteins of B. fragilis, are glycosylated.

63 We report a familial cluster of D. fragilis associated with marked peripheral eosinophilia

64 stimulating immunogen PS A1 from Bacteroides fragilis ATCC 25285/NCTC 9343 via a physiologically stab

65 umannii, Neisseria meningitidis, Bacteroides fragilis, Bacillus anthracis, Yersinia pestis, Francisel

66 Bacteroides fragilis (BF) is an integral component of the human colo

67 homologs, allow corrected annotations for B. fragilis bfr and other dpsl genes within the bacterial d

68 en (GlyAg) polysaccharide A from Bacteroides fragilis but not conventional peptides.

69 E. coli provided strong synergy to B. fragilis but not to C. perfringens.

70 nization with a human commensal, Bacteroides fragilis, but not with a polysaccharide A (PSA) deficien

71 This defect was overcome by gavage with B. fragilis, by immunization with B. fragilis polysaccharid

72 istent with the observation that Bacteroides fragilis can colonize the colon in the absence of facult

73 Bacteroides fragilis can replicate in atmospheres containing </=0.05

74 -negative opportunistic pathogen Bacteroides fragilis, can rescue the ultraviolet sensitivity of an E

75 The Bacteroides fragilis capsular polysaccharide complex is the major vi

76 hanism is similar to that of the Bacteroides fragilis capsular polysaccharides and establishes DNA in

77 that is increased by MIA and restored by B. fragilis causes certain behavioral abnormalities, sugges

78 o a preferred target site in the Bacteroides fragilis chromosome by a transposon-encoded targeting pr

79 ted from an antibiotic resistant Bacteroides fragilis clinical isolate.

80 detect the bft gene subtypes in Bacteroides fragilis clinical isolates.

81 al gastrointestinal inhabitants: Bacteroides fragilis, Clostridium perfringens, Escherichia coli, Kle

82 Our results therefore demonstrate that B. fragilis co-opts the Treg lineage differentiation pathwa

83 s in mice; however, Fpn is dispensable in B. fragilis colitis, wherein host proteases mediate BFT act

84 Notably, the CCF system is required for B. fragilis colonization following microbiome disruption wi

85 immunomodulatory activities of PSA during B. fragilis colonization include correcting systemic T cell

86 TLR2 on CD4(+) T cells is required for B. fragilis colonization of a unique mucosal niche in mice

87 The symbiont Bacteroides fragilis constitutes a relatively small proportion (up t

88 fspring with the human commensal Bacteroides fragilis corrects gut permeability, alters microbial com

89 The human commensal Bacteroides fragilis delivers immunomodulatory molecules to immune c

90 -type UDP-GlcA decarboxylases of Bacteroides fragilis, designated BfUxs1 and BfUxs2.

91 duced by the commensal bacterium Bacteroides fragilis directs development of the immune system of the

92 hat a prominent human commensal, Bacteroides fragilis, directs the development of Foxp3(+) regulatory

93 Clinical isolates of B. fragilis displayed a greater capacity for growth under m

94 There are 2 classes of B. fragilis distinguished by their ability to secrete a zin

95 Detection of D. fragilis DNA inside Enterobius vermicularis eggs agrees

96 Although B. fragilis does not normally grow with manNAc as the sole

97 A PSA mutant of B. fragilis does not restore these immunologic functions.

98 ensal and opportunistic pathogen Bacteroides fragilis does not synthesize the tetrapyrrole protoporph

99 ther the virulence mechanisms employed by B. fragilis during infections differ from those employed fo

100 dependent IL-10 production in response to B. fragilis during its pathogenic interactions with the hos

101 Here we demonstrate that B. fragilis encodes a cytochrome bd oxidase that is essenti

102 include common protozoa such as Dientamoeba fragilis, Entamoeba histolytica, or Cyclospora cayetanen

103 Our findings define a role for B. fragilis enterotoxin and its activating protease in the

104 ation between disease and the presence of B. fragilis enterotoxin.

105 (CNS), Peptostreptococcus spp., Bacteroides fragilis, Escherichia coli, Enterococcus spp., Pseudomon

106 Enterotoxigenic Bacteroides fragilis (ETBF) causes diarrhea and is implicated in inf

107 Enterotoxigenic Bacteroides fragilis (ETBF) has been implicated in inflammatory bowe

108 Enterotoxigenic Bacteroides fragilis (ETBF) is a commensal bacterium of great import

109 Enterotoxigenic Bacteroides fragilis (ETBF) is a Gram-negative, obligate anaerobe me

110 e, the bacterium enterotoxigenic Bacteroides fragilis (ETBF) is a significant source of chronic infla

111 human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel dis

112 Enterotoxigenic Bacteroides fragilis (ETBF) produces the Bacteroides fragilis toxin,

113 Enterotoxigenic Bacteroides fragilis (ETBF) secretes a 20-kDa metalloprotease toxin

114 enicity island (BfPAI) in enterotoxigenic B. fragilis (ETBF) strain 86-5443-2-2 and a related genetic

115 cter species and enterotoxigenic Bacteroides fragilis (ETBF), in 201 U.S. and European travelers with

116 n gut bacterium, enterotoxigenic Bacteroides fragilis (ETBF), to investigate the link between inflamm

117 The burden of enterotoxigenic Bacteroides fragilis (ETBF)-related diarrhea was determined in a bir

118 lonic bacterium, enterotoxigenic Bacteroides fragilis (ETBF).

119 those that do are called enterotoxigenic B. fragilis (ETBF).

120 or commensal bacterial Ags, in particular B. fragilis expressing polysaccharide A, in protecting agai

121 nd that addAB is required for survival of B. fragilis following DNA damage.

122 te such competition, we screened Bacteroides fragilis for the production of antimicrobial molecules.

123 Bacteroides fragilis, for example, synthesizes eight capsular polysa

124 Bacteroides fragilis GA3 is known to mediate potent inter-strain com

125 A Bacteroides fragilis gene (argF'(bf)), the disruption of which rende

126 Mutants in either B. fragilis gene displayed a fitness defect in competing fo

127 q increased reads mapping to the Bacteroides fragilis genome by 48- and 154-fold in mucus and tissue,

128 5LIW1) is the only protein encoded by the B. fragilis genome with significant identity to any known A

129 1 is located in a conserved region of the B. fragilis genome, whereas Bfuxs2 is in the heterogeneous

130 mediate additional DNA inversions of the B. fragilis genome.

131 scan of the Flavobacterium johnsoniae and B. fragilis genomes for putative promoters, resulting in 18

132 Analysis of the B. fragilis genomic sequence, together with genetic conserv

133 hingolipids, we found that treatment with B. fragilis glycosphingolipids-exemplified by an isolated p

134 romonas species (11.3%), and the Bacteroides fragilis group (10.2%).

135 Members of the Bacteroides fragilis group are among the most common anaerobic bacte

136 More Bacteroides fragilis group bacteremias were detected only in the FN

137 ypically resemble members of the Bacteroides fragilis group but phylogenetically display >5% 16S rRNA

138 in time to detection was greatest for the B. fragilis group: FN, 28 h, versus SN, 60.0 h.

139 One member of this family from Bacteroides fragilis had exquisite substrate specificity for the bra

140 ed from mice reconstituted with wild type B. fragilis had significantly enhanced rates of conversion

141 Here, we demonstrate that Bacteroides fragilis has a general O-glycosylation system.

142 The human gut symbiont Bacteroides fragilis has a general protein O-glycosylation system in

143 Fpn-deficient, enterotoxigenic B. fragilis has an attenuated ability to induce sepsis in m

144 The chromosome of Bacteroides fragilis has been shown to undergo 13 distinct DNA inver

145 Dientamoeba fragilis has emerged as an important and underrecognized

146 Among the Bacteroides spp. in the gut, B. fragilis has the unique ability of efficiently harvestin

147 similation and metabolism in the anaerobe B. fragilis have diverged from those of aerobic and faculta

148 pidemiology of enterotoxigenic strains of B. fragilis in clinical infections and whether there is a c

149 these findings for the pathophysiology of B. fragilis in extraintestinal infections and competition i

150 gnificantly reduced when co-cultured with B. fragilis in mixed biofilms.

151 the number of IRs are active processes of B. fragilis in the endogenous human intestinal ecosystem.

152 n of polysaccharide A (PSA) from Bacteroides fragilis in the endosome depends on the APC's having an

153 er, the identification of a cyst stage of D. fragilis in the stool of rodents infected with a human i

154 case of metronidazole-resistant Bacteroides fragilis in the United States and demonstrate the presen

155 onocolonization of germ-free animals with B. fragilis increases the suppressive capacity of Tregs and

156 ated and complex colonized mice, and from B. fragilis-induced murine abscesses.

157 ry molecule of the gut commensal Bacteroides fragilis, induces regulatory T cells to secrete the anti

158 Dientamoeba fragilis infection should be considered in the setting o

159 and secondary outcome was eradication of D. fragilis infection.

160 uch as Staphylococcus aureus and Bacteroides fragilis initiate this host response when transferred to

161 containing Escherichia coli and Bacteroides fragilis into the abdomens of rats (n = 9).

162 The opportunistic pathogen Bacteroides fragilis is a commensal organism in the large intestine,

163 Dientamoeba fragilis is a common enteropathogen of humans.

164 The anaerobe Bacteroides fragilis is a gram-negative, opportunistic pathogen that

165 The anaerobe Bacteroides fragilis is a highly aerotolerant, opportunistic pathoge

166 ride A (PSA) from the capsule of Bacteroides fragilis is a potent activator of CD4(+) T cells and tha

167 Enterotoxigenic anaerobic Bacteroides fragilis is a significant source of inflammatory diarrhe

168 Dientamoeba fragilis is a single-celled protozoan, closely related t

169 identify an alternative pathway by which B. fragilis is able to reestablish capsule production and m

170 on or commensalism, induction of IL-10 by B. fragilis is critical to this microbe's interactions with

171 errin deglycosylation occurs in vivo when B. fragilis is propagated in the rat tissue cage model of e

172 Bacteroides fragilis is the leading cause of anaerobic bacteremia an

173 Polysaccharide A (PSA) of Bacteroides fragilis is the model symbiotic immunomodulatory molecul

174 Bacteroides fragilis is the most common anaerobe isolated from clini

175 causing human gastrointestinal symptoms, D. fragilis is very common and is second only to Blastocyst

176 The obligate anaerobe, Bacteroides fragilis, is a highly aerotolerant intestinal tract orga

177 human intestinal microorganism, Bacteroides fragilis, is able to extensively modulate its surface.

178 e intestinal anaerobic symbiont, Bacteroides fragilis, is highly aerotolerant and resistant to H(2)O(

179 B. fragilis lacking PSA is unable to restrain T helper 17 c

180 naerobic, opportunistic pathogen Bacteroides fragilis lacks the glutathione/glutaredoxin redox system

181 Recolonization with wild type B. fragilis maintained resistance to EAE, whereas reconstit

182 specific recombinase family, conserved in B. fragilis, mediate additional DNA inversions of the B. fr

183 sence of C. difficile LuxS alleviates the B. fragilis-mediated growth inhibition.

184 tory molecule, polysaccharide A (PSA), of B. fragilis mediates the conversion of CD4(+) T cells into

185 port that the intestinal microbe Bacteroides fragilis modifies the homeostasis of host invariant natu

186 an altered serum metabolomic profile, and B. fragilis modulates levels of several metabolites.

187 Upon challenge with B. fragilis, mortality rates and serum proinflammatory cyto

188 eletion of its gene resulted in the first B. fragilis mutant able to synthesize only one phase-variab

189 as the sole carbon source, we isolated a B. fragilis mutant strain that can grow on this substrate,

190 We previously showed that a Bacteroides fragilis mutant unable to synthesize 4 of the 8 capsular

191 this study, we analysed the phenotype of B. fragilis mutants with defective protein glycosylation an

192 they are functional paralogs and that the B. fragilis NCTC 9343 PSF repeat unit contains xylose.

193 fy the sphingolipids produced by Bacteroides fragilis NCTC 9343.

194 found in the genome sequences of Bacteroides fragilis NCTC9343 and Bacteroides thetaiotaomicron VPI54

195 found to be present in the genome of the B. fragilis NCTC9343 strain but absent in strains 638R, YCH

196 In animals harbouring B. fragilis not expressing PSA, H. hepaticus colonization l

197 e that whereas both ETBF and nontoxigenic B. fragilis (NTBF) chronically colonize mice, only ETBF tri

198 that do not secrete BFT are nontoxigenic B. fragilis (NTBF), and those that do are called enterotoxi

199 ase indicates that amino acid residue 90 (B. fragilis numbering) plays an important role in conferrin

200 evelop abscesses following challenge with B. fragilis or abscess-inducing zwitterionic polysaccharide

201 The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prev

202 acterioferritin-related (bfr) gene in the B. fragilis oxidative stress response.

203 t into the role of individual Trxs in the B. fragilis oxidative stress response.

204 The genetic element flanking the Bacteroides fragilis pathogenicity island (BfPAI) in enterotoxigenic

205 oproteinase II (MPII)) are encoded by the B. fragilis pathogenicity island.

206 microbial biogeography within the colon, B. fragilis penetrates the colonic mucus and resides deep w

207 y recognized as human parasites: Dientamoeba fragilis, Pentatrichomonas hominis, Trichomonas vaginali

208 ort the cloning and overexpression of the B. fragilis phosphonopyruvate decarboxylase gene (aepY), pu

209 ge with B. fragilis, by immunization with B. fragilis polysaccharides, or by adoptive transfer of B.

210 We find that intra-individual B. fragilis populations contain substantial de novo nucleot

211 upport routine metronidazole treatment of D. fragilis positive children with chronic gastrointestinal

212 F was isolated from 20.3% (40/197) of the B. fragilis-positive diarrheal specimens and from 8.1% (15/

213 l specimens and from 8.1% (15/185) of the B. fragilis-positive nondiarrheal specimens (P < .001) and

214 Of 382 B. fragilis-positive specimens, 14.4% of the strains found

215 Thus, B. fragilis possesses a new pathway of NANA utilization, wh

216 reactivity against Bacteroides vulgatus, B. fragilis, Prevotella intermedia, and, to a lesser extent

217 , but symptoms are relieved by a Bacteroides fragilis probiotic.

218 Bacteroides fragilis produces a capsular polysaccharide (PSA), which

219 ination, and we demonstrate that Bacteroides fragilis producing a bacterial capsular polysaccharide A

220 utes to sepsis in mice, and we identify a B. fragilis protease called fragipain (Fpn) that is require

221 In the gut, Bacteroides fragilis protects against colitis through induction of i

222 hat the prominent human symbiont Bacteroides fragilis protects animals from experimental colitis indu

223 r the human intestinal commensal Bacteroides fragilis, protects against central nervous system demyel

224 In B. fragilis, protein glycosylation is a fundamental and ess

225 C. perfringens and B. fragilis provided moderate synergy to each other but onl

226 In Bacteroides fragilis, PS synthesis is regulated so that only one of

227 y effects of the archetypal ZPS, Bacteroides fragilis PSA.

228 in the important human symbiont Bacteroides fragilis raised the critical question of how these molec

229 We reveal that Bacteroides fragilis releases PSA in outer membrane vesicles (OMVs)

230 toca, Staphylococcus aureus, and Bacteroides fragilis remains largely undefined and test availability

231 eria, Bifidobacterium longum and Bacteroides fragilis, representative members of the gut microbiota,

232 ion of the gnotobiotic mouse intestine by B. fragilis requires that the organism synthesize only a si

233 ns from Bacteroides vulgatus and Bacteroides fragilis respectively are members of the Pfam family PF1

234 stitution with polysaccharide A-deficient B. fragilis restored EAE susceptibility.

235 in a non-metabolizing relative, Bacteroides fragilis, resulted in gain of glucosinolate metabolism.

236 ccf genes in the model symbiont, Bacteroides fragilis, results in colonization defects in mice and re

237 he presence of the uroS and yifB genes in B. fragilis seems to be linked to pathophysiological and nu

238 ulated with Escherichia coli and Bacteroides fragilis (sepsis).

239 TTTG/TANNTTTG) were identical to Bacteroides fragilis sigma(ABfr) consensus -33/-7 promoter elements

240 mbiosis factor (PSA, polysaccharide A) of B. fragilis signals through TLR2 directly on Foxp3(+) regul

241 lysaccharides, or by adoptive transfer of B. fragilis-specific T cells.

242 be transferred from ETBF to nontoxigenic B. fragilis strains by a mechanism similar to that for the

243 tic colonization of mammals, we generated B. fragilis strains deleted in the global regulator of poly

244 5-nitroimidazole antimicrobial agents in B. fragilis strains from Europe and Africa.

245 he possibility of metronidazole-resistant B. fragilis strains in the United States and the importance

246 acteroidales strains analyzed, except for B. fragilis strains with the same T6SS locus.

247 lobal regulatory nature of the process in B. fragilis suggest an evolutionarily ancient mechanism for

248 Bioassay-driven purification of B. fragilis supernatant led to the isolation of the growth

249 Rickenellaceae, Parabacteroides, Bacteroides fragilis, Sutterella, Lachnospiraceae, 4-methyl-2-pentan

250 oles between the two species (as Bacteroides fragilis switches roles between humans and mice)(2).

251 A single strain of Bacteroides fragilis synthesizes eight distinct capsular polysacchar

252 Bacteroides fragilis synthesizes eight distinct capsular polysacchar

253 e (Bacteroides thetaiotaomicron, Bacteroides fragilis, Tannerella forsythensis, Porphyromonas gingiva

254 Enterotoxigenic Bacteroides fragilis that secrete a zinc-dependent metalloprotease t

255 rocesses in metabolically active Bacteroides fragilis The ability to visualize fluorescently labeled

256 ributing to the pathogenicity of Bacteroides fragilis, the most common anaerobic species isolated fro

257 In this study, the six B. fragilis thioredoxins (Trxs) were investigated to determ

258 as the time required (foraging time) for S. fragilis to approach its preferred food (giant kelp) in

259 ngs the total of oxyR-controlled genes in B. fragilis to five and suggests the existence of a second

260 of these genes eliminates the ability of B. fragilis to grow on NANA.

261 , which required the presence of Bacteroides fragilis to grow.

262 e stress are physiological adaptations of B. fragilis to its environment that enhance survival in ext

263 n this study, we show that the ability of B. fragilis to utilize heme or protoporphyrin IX for growth

264 role of the C-terminal region in Bacteroides fragilis toxin (BFT) activity, processing, and secretion

265 ETBF that secretes B. fragilis toxin (BFT) causes human inflammatory diarrhea

266 ependent metalloprotease toxin termed the B. fragilis toxin (BFT) have been associated with acute dia

267 Bacteroides fragilis toxin (BFT) is a protein secreted by enterotoxi

268 The Bacteroides fragilis toxin (BFT) is the only known virulence factor

269 zinc-binding metalloprotease in Bacteroides fragilis toxin (BFT) processing and activity, the zinc-b

270 We now demonstrate that purified B. fragilis toxin (BFT) up-regulates SMO in HT29/c1 and T84

271 own ETBF virulence factor is the Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage,

272 ethal disease from ETBF colonization in a B. fragilis toxin (BFT)-dependent manner.

273 tes a 20-kDa metalloprotease toxin termed B. fragilis toxin (BFT).

274 on is dependent on ETBF-secreted Bacteroides fragilis toxin (BFT).

275 rmation in mice through the production of B. fragilis toxin (BFT).

276 e a zinc-dependent metalloprotease toxin, B. fragilis toxin (BFT).

277 Enterotoxigenic strains that produce B. fragilis toxin (BFT, fragilysin) contribute to colitis a

278 des fragilis (ETBF) produces the Bacteroides fragilis toxin, which has been associated with acute dia

279 Expression of the B. fragilis trxB gene was induced following treatment with

280 Unlike the other described Tsrs of B. fragilis, Tsr19 brings about inversion of two DNA region

281 onserved ICE and are confined to Bacteroides fragilis Unlike GA1 and GA2 T6SS loci, most GA3 loci do

282 ic pathways for C. difficile WT, luxS and B. fragilis upon co-culture, indicating that AI-2 may be in

283 Near the epithelium, B. fragilis upregulated numerous genes involved in protein

284 and enzyme kinetics assays indicate that B. fragilis UroS is functionally different from canonical b

285 The data provided herein suggest that B. fragilis uses N-succinyl-L-ornithine rather than N-acety

286 pathway for binuclear CcrA from Bacteroides fragilis using density functional theory based quantum m

287 The prevalence of D. fragilis varies between 0% to over 82%; results depend o

288 MPII and FRA is required for the overall B. fragilis virulence in vivo.

289 B. fragilis was anergistic (antagonistic) to E. coli in coi

290 te-specific recombinase (Tsr) of Bacteroides fragilis was characterized.

291 Eradication of D. fragilis was significantly greater in the metronidazole

292 et, the zinc beta-lactamase from Bacteroides fragilis, was screened against the fragment-like subset

293 onses specific for B. thetaiotaomicron or B. fragilis were associated with the efficacy of CTLA-4 blo

294 biosynthesis locus promoters of Bacteroides fragilis were determined from bacteria grown in vitro, f

295 ons with a common gut bacterium, Bacteroides fragilis, were studied.

296 B. fragilis, which by itself is immunogenic, did not promot

297 unistic human anaerobic pathogen Bacteroides fragilis, which is currently classified as a nonhemolyti

298 aracterized the nanLET operon in Bacteroides fragilis, whose products are required for the utilizatio

299 s against CTLA-4 favored the outgrowth of B. fragilis with anticancer properties.

300 TBF) strains, a nontoxigenic WT strain of B. fragilis (WT-NTBF), WT-NTBF overexpressing bft (rETBF),

301 ia coli, Neisseria meningitidis, Bacteroides fragilis, Yersinia pestis, Chlamydia trachomatis, Porphy