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1 n, deparaffinized, various stains, unstained fresh-frozen).
2 hin 24 to 36 hours of death, and immediately fresh frozen.
3 , stained with hematoxylin and eosin, and/or fresh frozen.
4 Each sample was divided into four parts: (1) fresh-frozen, (2) direct-fixed in formalin for 18 h, (3)
5 (2), ITB; 1.1 +/- 0.5 mm(2), DM) compared to fresh-frozen (5.8 +/- 2.1mm(2), ITB; 3.1 +/- 1.2mm(2), D
10 e performed a pilot study that compared both fresh frozen and formalin-fixed paraffin-embedded health
13 We validate our method on cell-line data, fresh frozen and paraffin-embedded tumour tissue samples
14 dant potential of irradiated (0.5 and 1 kGy) fresh, frozen and dried samples were determined by chrom
15 f hematopoietic subsets in RNA mixtures from fresh, frozen and fixed tissues, including solid tumors,
16 hod can be applied to all kinds of products; fresh, frozen and processed, including those undergoing
18 e cross-sectional area (CSA) measurements of fresh-frozen and Crosado-embalmed collagen-rich tissues,
19 on of DNA copy number alterations from small fresh-frozen and FFPE clinical tumor specimens, although
20 lon were recovered in comparable yields from fresh-frozen and FFPE preserved tissues of rodents treat
22 nd immunohistochemistry were performed using fresh-frozen and formalin-fixed tissue samples of tumor
23 s immune populations (n = 184,126 cells) and fresh-frozen and formalin-fixed, paraffin-embedded brain
25 er injection, and their hearts were excised, fresh frozen, and sectioned for histology and immunohist
30 adverse events associated with placement of fresh-frozen bone allografts (FFBAs) during alveolar rid
36 omatic genetic variations were identified in fresh frozen clinical specimens by Illumina RNA-sequenci
37 ius) mince with different thermal histories (fresh, frozen, cooked) as affected by pH, water and NaCl
38 and endothelial cells) protein expression in fresh-frozen corneal tissue suggests that Fas ligand exp
39 man donors, aged stillborn to 85 years, were fresh frozen, cryostat sectioned, and prepared for indir
40 onors (age range, 6 months to 67 years) were fresh frozen, cryostat sectioned, and prepared for indir
42 ral heads from five embalmed donors and five fresh-frozen donors were compared using Raman microspect
45 tion mass spectrometry imaging (DESI-MSI) of fresh-frozen excision specimens, including cancer and pa
47 h for employing LCM of epithelial cells from fresh frozen fetal tissue that enables quantitative anal
49 ody validation procedure and applied it onto fresh frozen (FF) and formalin-fixed and paraffin-embedd
50 titation of PTEN concentrations in cells and fresh frozen (FF) and formalin-fixed paraffin-embedded (
51 ide samples; 25 of these had direct FFPE vs. fresh frozen (FF) replicates, 57 were sequenced in 2 dif
52 ject, comparing 578 FFPE samples with 11,014 fresh frozen (FF) samples across multiple tumour types.
53 formalin-fixed paraffin embedded (FFPE) and fresh frozen (FF) sequential patient-matched breast tumo
55 steps were adapted to three tissue sources: fresh frozen (FF), optimal cutting temperature (OCT) com
56 cruited in Barcelona, Spain and included 112 fresh frozen (FF, median age 69, 44% women) and 163 form
62 we assessed the expression of SEPT9 in 7287 fresh frozen human tissue samples and 292 human cell lin
65 ng spatial transcriptomics and proteomics on fresh-frozen human MS brain tissue, we identified multic
66 )H-CBD-2115 (also known as (3)H-OXD-2115) in fresh-frozen human postmortem CTE brain tissue (stages I
67 .g., Crosado ITB PEG only 306 +/- 91 MPa vs. fresh-frozen ITB PEG only 108 +/- 31 MPa; mean +/- stand
68 e.g., Crosado ITB PEG only 46 +/- 15 MPa vs. fresh-frozen ITB PEG only 21 +/- 8 MPa; p < 0.001) when
69 hin human glomeruli from a normal portion of fresh-frozen kidney cancer nephrectomy tissue revealing
72 erns obtained directly from small amounts of fresh frozen lung-tumour tissue could be used to accurat
73 mune markers were assessed in parallel using fresh-frozen lung tissue from sibling rats of the same c
74 in 8-microm tissue sections obtained from a fresh frozen lymph node tumor infiltrated by metastatic
75 s for fresh plant tissue, formalin-fixed and fresh frozen mammalian tissue, fixed cells and biofluids
76 be used to interrogate DNA from cell lines, fresh frozen material and FFPE samples to assess copy nu
77 multiple sclerosis (n = 108, 34 males) with fresh frozen material available for genetic analyses and
79 hival samples and the insufficient access to fresh-frozen material are partly the cause of the delaye
83 he whole-genome sequencing (WGS) analysis of fresh-frozen metastatic biopsies from 197 mCRPC patients
84 s were derived from the IMS investigation of fresh frozen mouse liver and rabbit adrenal gland tissue
85 nable multimodal MALDI IMS of undecalcified, fresh-frozen murine femurs, allowing the distribution of
87 al contrast echocardiography and then either fresh frozen or embedded in paraffin were determined by
88 ylation of DNA extracted from microdissected fresh frozen or formalin-fixed paraffin-embedded tissue
90 ng to search for somatic mosaic mutations in fresh, frozen, or fixed archival tissue from six affecte
91 nome analysis of DNA methylation profiles in fresh-frozen oropharyngeal squamous cell carcinoma (OPSC
94 med on a heterogenous set of 221 FFPE and 32 fresh frozen pediatric solid tumor and lymphoma specimen
97 , and albumin dissolvent (68.1%) compared to fresh frozen plasma (28.6%) and sterile water (20.0%) (P
98 s of platelets (10.0 versus 6.6 U, P<0.012), fresh frozen plasma (4.8 versus 3.1 U, P<0.03), and cryo
99 zard ratio = 1.55 [1.09-2.20]; p = 0.01) and fresh frozen plasma (cause-specific hazard ratio = 1.38
100 ns for use of other blood components such as fresh frozen plasma (FFP) and platelet transfusions are
101 sought to define the overall utilization of fresh frozen plasma (FFP) and platelets and the impact o
102 tments utilized in clinical practice include fresh frozen plasma (FFP) and prothrombin complex concen
106 from Iraq supporting early aggressive use of fresh frozen plasma (FFP) in a 1:1 ratio to packed red b
107 plasma volume was removed and replaced with fresh frozen plasma (FFP) or with 50% FFP and 50% albumi
109 The practice of a high transfusion ratio of fresh frozen plasma (FFP) to red blood cells (RBCs) has
111 amounts of packed red blood cells (RBCs) and fresh frozen plasma (FFP) were recorded during hospital
112 raoperative aVWS received significantly more fresh frozen plasma (P = .016) and fibrinogen concentrat
113 ion of packed red blood cells (p = .442) and fresh frozen plasma (p = .063) were not different betwee
115 95% confidence interval [CI], 0.57 to 0.99), fresh frozen plasma (RR, 0.37; 95% CI, 0.21 to 0.64), an
116 8 U blood products (red blood cells [RBCs] + fresh frozen plasma [FFP] + platelets) had a median (int
117 transfused with all three blood components (fresh frozen plasma [FFP], PLTs, and cryoprecipitate) ve
120 ents who received a total of 46,101 units of fresh frozen plasma and 6,251 units of apheresis platele
122 ransfusion of high plasma volume components, fresh frozen plasma and apheresis platelets, from potent
123 tive RAR parameters predicted transfusion of fresh frozen plasma and cryoprecipitate with modest to h
124 ) of 65 received blood products (15 received fresh frozen plasma and eight received red blood cell co
126 analysis to evaluate the association between fresh frozen plasma and infectious complication, control
127 gnificant dose-response relationship between fresh frozen plasma and infectious complications (p = .0
129 ine concentrations, the amount of platelets, fresh frozen plasma and packed erythrocytes used, and th
132 or the continued unbridled administration of fresh frozen plasma and platelets without objective evid
133 ave shown to reduce bleeding, transfusion of fresh frozen plasma and platelets, and possibly mortalit
136 association was found between transfusion of fresh frozen plasma and ventilator-associated pneumonia
143 otal of 380 non-trauma patients who received fresh frozen plasma from 2004 to 2005 were compared with
145 ciation between infection and transfusion of fresh frozen plasma in patients who did not receive conc
148 o >1.5) or clinical (transfusion >2 units of fresh frozen plasma or >1 pack of platelets in 6 hours)
152 io-based transfusion (packed red blood cells:fresh frozen plasma ratio of 1:1 to 2:1) and were treate
155 BEST PRACTICE ADVICE 6: The large volume of fresh frozen plasma required to reach an arbitrary inter
156 ction without prior PVE demonstrated a lower fresh frozen plasma requirement (P = 0.01), a lower peak
157 ence of reactions to platelets compared with fresh frozen plasma suggests that a platelet-related fac
158 with an odds ratio of infection per unit of fresh frozen plasma transfused equal to 1.039 (1.013-1.0
159 -test allowed comparison of average units of fresh frozen plasma transfused to patients with and with
160 [0-4] versus 1.1 units [0-3]; P = 0.21), or fresh frozen plasma transfusion requirements (0 unit [0-
161 rative packed red cells (r=0.28, P=.049) and fresh frozen plasma transfusions (r=0.42, P=.004), highe
164 of platelet units (4.3 vs. 1.7, p =.05) and fresh frozen plasma units (1.1 vs. 0.6, p =.08) also was
165 tests) and the transfusion (blood units and fresh frozen plasma units) during the operative period w
166 id infusion volume (6.1-3.2 L) and increased fresh frozen plasma use (3.2-10.1 U) (both P < .05) in t
167 unoglobulin (4 cases), interferon (3 cases), fresh frozen plasma with WNV IgG (2 cases), and ribaviri
168 ood products (red blood cells, platelets, or fresh frozen plasma) administered during transplantation
169 platelets, 12.5 +/- 5.4 U vs. 8.6 +/- 6.4 U; fresh frozen plasma, 9.6 +/- 4.9 U vs. 4.9 +/- 3.6 U; an
170 core analysis adjusting by use of platelets, fresh frozen plasma, and cryoprecipitate; and adjusting
171 h a 68%, 56%, and 58% reduction in platelet, fresh frozen plasma, and packed erythrocyte usage, respe
172 used patients, pooled platelet concentrates, fresh frozen plasma, and packed red cells collected usin
173 ed significantly less volume of packed RBCs, fresh frozen plasma, and platelet transfusion (p < 0.001
174 ng administration of packed red blood cells, fresh frozen plasma, and platelets in ratios approximati
175 gulation factor assays were compared between fresh frozen plasma, COVID-19 convalescent plasma, and p
177 The administration of coagulation factors (fresh frozen plasma, prothrombin complex concentrates or
179 apy and treatment with lactulose, vitamin K, fresh frozen plasma, ventilatory assistance, and intensi
190 high (>= 1:1) and medium (>= 1:2 and < 1:1) fresh frozen plasma:packed RBC ratio groups, respectivel
191 ts (0.1 [0.04] vs 1.9 U [4.5] p=0.0001), and fresh-frozen plasma (0.1 [0.07] vs 0.75 U [0.21] p=0.000
194 nesthetized mice were transfused with murine fresh-frozen plasma (mFFP), PCC, mixtures of human vitam
195 use of a combination of packed red cells and fresh-frozen plasma (reconstituted blood) for priming of
197 ulopathy unresponsive to vitamin K requiring fresh-frozen plasma after the first 24 hours postresecti
198 both platelets and coagulant products (e.g., fresh-frozen plasma and recombinant-activated factor VII
200 use of a combination of packed red cells and fresh-frozen plasma during surgery for congenital heart
201 anticoagulation, and/or plasmapheresis with fresh-frozen plasma exchange, resolved TMA in most patie
207 nternational normalized ratios, 33% received fresh-frozen plasma transfusions during their intensive
210 from 7.8% to 92.8% for RBCs, 0% to 97.5% for fresh-frozen plasma, and 0.4% to 90.4% for platelets.
211 s and infusing those with abnormalities with fresh-frozen plasma, coagulation factor concentrates, or
212 e vWf-cleaving metalloprotease is present in fresh-frozen plasma, in cryoprecipitate-depleted plasma
213 ive bleeding disorder treated by infusion of fresh-frozen plasma, plasma-derived FVII concentrates an
215 cluded sample type comparisons (whole blood, fresh/frozen plasma, and capillary finger prick) and pre
219 n profiling was performed in 140 samples, 47 fresh frozen samples and 93 FFPE samples, on HU133_Plus_
220 nt data sets that used similar platforms and fresh frozen samples, the average differences were 11% t
223 performed comprehensive genomic analyses on fresh-frozen samples from 348 patients affected by prima
225 genome-wide expression profiling studies of fresh-frozen samples were validated in the formalin-fixe
230 estigated by immunohistochemical analysis of fresh frozen skin specimens using multiple lymphocytic m
231 e-transcription polymerase chain reaction in fresh-frozen skin biopsies and whole-genome sequencing.
232 is based on the low temperature embedding of fresh frozen specimens into a hydrogel matrix composed o
233 tide polymorphism microarray platform, of 60 fresh-frozen specimens that represent the main salivary
234 ue imaging using a variety of samples, using fresh frozen surgical prostate resections and formalin-f
235 trans-pedicular access to the vertebra using fresh-frozen thoraco-lumbar vertebrae from two female bo
237 tic study, the MSPen was used to analyze 184 fresh-frozen thyroid, parathyroid, and lymph node tissue
239 Mass spectra are acquired directly from fresh frozen tissue sections using matrix-assisted laser
241 s of photoreceptors were microdissected from fresh frozen tissue, RNA was purified, and quantitative
242 ings demonstrate for the first time that, in fresh frozen tissue, that the anatomical distribution of
248 trometry profiles from 10-microm sections of fresh-frozen tissue samples: 25 normal lung, 29 normal b
250 mal setup for the analysis of cell cultures, fresh-frozen tissue sections and in vivo experiments on
252 ass of in situ probes that can be applied to fresh-frozen tissue sections in a manner analogous to im
254 hnical differences (e.g., formalin-fixed vs. fresh-frozen tissue), the distribution of mutations and
256 hylation-Specific PCR (MSP), performed using fresh-frozen tissue, was used to determine the methylati
260 ing human lung cancer tissue microarrays and fresh frozen tissues, we found that the overexpression o
261 ed and purified from 134 tissue samples from fresh-frozen tissues (n = 87) or formalin-fixed, paraffi
267 I-MSI analysis typically involves sectioning fresh-frozen tissues or, less commonly, embedding sample
270 roof-of-concept examples of MSI for FFPE and fresh-frozen tissues, with no post-sectioning sample pre
273 tic remanence measurements of 147 samples of fresh/frozen tissues, from Alzheimer's disease (AD) and
274 dy epigenetics in clear-cell ovarian cancer, fresh frozen tumor DNA (n = 485) was assayed on Illumina
276 Therefore, we examined B7-H4 expression in fresh-frozen tumor specimens from 259 renal cell carcino
277 64 primary, 41 metastatic, and 17 recurrent fresh-frozen tumors from 77 patients along with matched
278 , copy number profiling was limited to large fresh-frozen tumors where intact DNA could be readily ex
280 n aqueous extracts of human fecal specimens (fresh, frozen, unfixed, or fixed in 5 or 10% formalin or
281 cedures used in pathology, we selected small fresh frozen uterine tissue samples to investigate how t
283 was performed on genomic DNA extracted from fresh-frozen whole blood and patient-matched tumor pairs
284 zed from isolated pancreatic islets and from fresh-frozen whole pancreatic tissue using PCR and seque