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1 DS for 4 species (human, mouse, nematode and fruit fly).
2 gh a case study of gradient formation in the fruit fly.
3 in mammals also affect cardiac ageing in the fruit fly.
4 ian and seasonal patterns of behavior in the fruit fly.
5 neurons in the ventral nervous system of the fruit fly.
6  manipulate and study neural circuits in the fruit fly.
7 potential biocontrol techniques against this fruit fly.
8 des for a deoxynucleotide transporter in the fruit fly.
9 fectively used to control this Mediterranean fruit fly.
10 e implemented in the olfactory system of the fruit fly.
11 n motifs appear to be conserved in mouse and fruit fly.
12 t player in a subset of clock neurons of the fruit fly.
13 organisms, including bacteria, nematodes and fruit flies.
14 nt because it is required for development in fruit flies.
15 wo alleles of a key detoxification enzyme in fruit flies.
16 s function in species ranging from humans to fruit flies.
17 l networks underlying the behavior of larval fruit flies.
18  particles (NAPs) from imidacloprid (IMI) on fruit flies.
19 is responsible for increasing sleep in young fruit flies.
20 mulate the olfactory system in Drosophila or fruit flies.
21 vivo voltage imaging in mice, zebrafish, and fruit flies.
22 onmental water samples and in the ovaries of fruit flies.
23  many animals, including mice, zebrafish and fruit flies.
24 ransduction process are, however, scarce for fruit flies.
25 boundaries from high resolution Hi-C data in fruit flies.
26 ids in the brain of Drosophila melanogaster (fruit fly), a major invertebrate model system in biologi
27 ervasive in these butterflies as compared to fruit flies, a fact that curiously results in very simil
28 ster and an array of viruses that infect the fruit fly acutely or persistently or are vertically tran
29 olutionary advantage of adaptively divergent fruit fly aggression phenotypes from different environme
30 s both enhance aggressive behaviour in olive fruit flies, allowing them to achieve higher fighting su
31 tor was also used to transform the Caribbean fruit fly, Anastrepha suspensa, indicating a wide range
32 af-32 that are enriched in TAD boundaries in fruit flies and also several unreported motifs.
33 acid), are detected by animals as diverse as fruit flies and humans, consistent with a near-universal
34                Long-lived dietary restricted fruit flies and insulin-like-peptide mutants exhibit sma
35 form II, which is much faster acting against fruit flies and mosquitoes.
36            During exposure to anoxic stress, fruit flies and other poikilotherms enter into a reversi
37 n Drosophila melanogaster S2 cells and adult fruit flies and results in increased SG formation.
38 ORC2) declines with age in the brain of both fruit flies and rodents and that the loss of mTORC2-medi
39  In this study, we analyze the locomotion of fruit flies and show that this non-stereotyped behavior
40 lidated LEAP using videos of freely behaving fruit flies and tracked 32 distinct points to describe t
41 x novel viruses in the viromes of laboratory fruit flies and wild populations of two insect vectors:
42 hat Met restriction extends lifespan in both fruit flies and yeast, and that this effect requires low
43 pective, we explore some of the strengths of fruit flies and zebrafish for addressing fundamental can
44 e been analyzed in detail, especially in the fruit fly and desert locust, understanding of the organi
45 R) motifs that interact with CAF1s in yeast, fruit fly and mammals.
46 dy shape, whereas published knockouts of the fruit fly and mouse orthologous genes resulted in lethal
47 repsiptera and has recently been recorded in fruit fly and spider lineages.
48   We demonstrated in cultured neurons and in fruit fly and zebrafish larvae how single cells could be
49 poral resolution in Drosophila melanogaster (fruit fly) and Danio rerio (zebrafish) to quantify signa
50 nown proteins was validated in invertebrate (fruit fly) and vertebrate (mouse) models.
51  H2S production was observed in yeast, worm, fruit fly, and rodent models of DR-mediated longevity.
52 of model systems, including yeast, nematode, fruit fly, and zebrafish, and discuss emerging methods f
53  the combinatorial odor code supplied by the fruit fly antenna is a very simple one in which nearly a
54                                     Although fruit flies are a common laboratory model organism of ch
55                                              Fruit flies are a far cry from the quaint genetic model
56 e behavior, but examples of such behavior in fruit flies are rare.
57                           However, tephritid fruit flies are responsible for both direct and indirect
58                               Experiments on fruit flies are shedding new light on the evolution and
59                                Barnacles and fruit flies are two prominent model marine and terrestri
60 is is one of the most economically important fruit flies around the world.
61                         Although we focus on fruit flies as a case study, the framework for our simul
62 del parasites and five species of Drosophila fruit flies as model hosts.
63 analyses of chemosensory genes in the citrus fruit fly B. minax provided new insights for preventive
64                                   The citrus fruit fly Bactrocera (Tetradacus) minax is a major and d
65 rly steps of spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata (Solanum fly) have been
66 interactions of olive and the obligate olive fruit fly (Bactrocera oleae), and alter the economics of
67 nsposable element isolated from the Oriental fruit fly, Bactrocera dorsalis, is distantly related to
68                          We tested the olive fruit fly, Bactrocera oleae (Diptera: Tephritidae), as a
69                                   Queensland fruit fly, Bactrocera tryoni (Froggatt), is the most sig
70 nd compare our results to two routinely used fruit fly balancer chromosomes.
71 he presence of female sex pheromone of olive fruit fly before the onset of pest infestation in an orc
72 sleep to a single pair of neurons within the fruit fly brain and provide a system for investigating t
73        We questioned whether activity in the fruit fly brain is different during such closed-loop beh
74   identified a single pair of neurons in the fruit fly brain that directly senses 'blood' glucose lev
75 ts have created the most detailed map of the fruit fly brain to date, identifying over 25,000 neurons
76                            In the developing fruit fly brain, a protein called Trithorax increases th
77 timulate wake-promoting clock neurons in the fruit fly brain.
78 s have long been known to attract laboratory fruit flies, but small spots, presumably common in the w
79      We manipulated the antennal function of fruit flies by ablating their aristae, forcing them to r
80 ow gene determines sex-specific behaviors in fruit flies by acting in the brain.
81 hanism that causes the 'Minute' phenotype in fruit flies can explain how organisms are able to elimin
82          Studying the auditory system of the fruit fly can reveal how hearing works in mammals.
83 nvasion and ageing studies-the Mediterranean fruit fly (Ceratitis capitata)- we investigated how age,
84                            The Mediterranean fruit fly, Ceratitis capitata Wiedemann, is a deleteriou
85 insect pest species, including Mediterranean fruit fly, Ceratitis capitata.
86 erences in the inhibition pattern enable the fruit fly circuit to respond faster to heading changes w
87          Here, in a case study involving the fruit fly clock, we demonstrate that VRC analysis provid
88                       The skeletal muscle of fruit flies communicates with other organs to prevent th
89  diseases, but high-resolution structures of fruit fly contractile proteins have not been determined.
90 rated TE libraries: Drosophila melanogaster (fruit fly), Danio rerio (zebrafish), and Oryza sativa (r
91 ed hyperactivity in Drosophila melanogaster (fruit fly), demonstrating that PLD mediates behavioral r
92          Moreover, our real data analysis of fruit fly developmental time course RNA-Seq data demonst
93 raconidae), that attack Rhagoletis pomonella fruit flies (Diptera: Tephritidae).
94 10A ensures that germline stem cells in male fruit flies divide to produce two sibling cells that are
95                 During olfactory learning in fruit flies, dopaminergic neurons assign value to odor r
96 gh recent reports have demonstrated that the fruit flies Drosophila melanogaster are capable of visua
97 roblem of motion estimation, focusing on the fruit fly Drosophila and the mouse retina.
98                                    Using the fruit fly Drosophila as an example, we discuss recent wo
99 y relating field abundance of the rainforest fruit fly Drosophila birchii to ecological change across
100                       Two new studies in the fruit fly Drosophila demonstrate unexpected molecular, a
101 oup of local, inhibitory interneurons in the fruit fly Drosophila key for filtering these cues.
102      Paraquat is thus frequently used in the fruit fly Drosophila melanogaster and other animal model
103 ve demonstrated that molecular clocks in the fruit fly Drosophila melanogaster are regulated differen
104                    Whether you are using the fruit fly Drosophila melanogaster as an experimental sys
105 nd required for mesoderm invagination in the fruit fly Drosophila melanogaster but do not appear duri
106                                          The fruit fly Drosophila melanogaster exhibits robust odor-g
107                                       As the fruit fly Drosophila melanogaster expresses Tau proteins
108                                          The fruit fly Drosophila melanogaster has become a valuable
109                                          The fruit fly Drosophila melanogaster has long been used as
110                                          The fruit fly Drosophila melanogaster has only one histone H
111  Schretter et al. (2018) demonstrated in the fruit fly Drosophila melanogaster how an enzyme from spe
112                                          The fruit fly Drosophila melanogaster is a widely used model
113                                          The fruit fly Drosophila melanogaster is an excellent model
114 on of the tsetse fly antenna and that of the fruit fly Drosophila melanogaster One morphological type
115 ronal substrates of reward perception in the fruit fly Drosophila melanogaster prompted us to develop
116 pid life cycle, and genetic amenability, the fruit fly Drosophila melanogaster provides an attractive
117 Myc-induced cell-autonomous apoptosis in the fruit fly Drosophila melanogaster relies on an intergeni
118  Here we demonstrate that mate choice in the fruit fly Drosophila melanogaster results in the linear
119                               A study in the fruit fly Drosophila melanogaster shows that satellite D
120 lumnar (LC) neurons in the optic lobe of the fruit fly Drosophila melanogaster to characterize diverg
121                  Here, we used adults of the fruit fly Drosophila melanogaster to investigate the met
122                   In this study, we used the fruit fly Drosophila melanogaster to show that developme
123                    Among these is the common fruit fly Drosophila melanogaster, a well-established mo
124  the powerful genetic tools available in the fruit fly Drosophila melanogaster, an outline of the neu
125   Notably, SKI-1/S1P of arthropods, like the fruit fly Drosophila melanogaster, contains a shorter pr
126                                       In the fruit fly Drosophila melanogaster, interlocked negative
127            Alternative models, including the fruit fly Drosophila melanogaster, show remarkable simil
128  the latest reference genome assembly of the fruit fly Drosophila melanogaster, was released by the B
129                                    Using the fruit fly Drosophila melanogaster, we identified neurons
130               This mechanism is found in the fruit fly Drosophila melanogaster, where polyploid ovari
131                                       In the fruit fly Drosophila melanogaster, which shows a robust
132 ial behaviour in many species, including the fruit fly Drosophila melanogaster.
133  genes that are modulated upon mating in the fruit fly Drosophila melanogaster.
134 rs that influence aggressive behavior of the fruit fly Drosophila melanogaster.
135 mulation of dead neurons in the brain of the fruit fly Drosophila melanogaster.
136 asts) to the published neuroblast map of the fruit fly Drosophila melanogaster.
137 s depicting embryonic gene expression in the fruit fly Drosophila melanogaster.
138 tasis and ageing in the antennal ears of the fruit fly Drosophila melanogaster.
139 find that Sir2 in the mushroom bodies of the fruit fly Drosophila promotes short-term ethanol-induced
140 he nematode worm Caenorhabditis elegans, the fruit fly Drosophila, and mice.
141                                       In the fruit fly Drosophila, head formation is driven by a sing
142             Here, we demonstrate that in the fruit fly Drosophila, the illusory motion percept is gen
143  our DNNto data from the early embryo of the fruit fly Drosophila, this system serves as a test bed f
144  ageing in laboratory animals, including the fruit fly Drosophila.
145                                 For example, fruit flies (Drosophila melanogaster) avoid an odor afte
146 contrast, Ae1a was lethal to closely related fruit flies (Drosophila melanogaster) but induced no adv
147 re and function of mitochondria in mouse and fruit flies (Drosophila melanogaster) by electron cryo-t
148  of the contact insecticidal activity toward fruit flies (Drosophila melanogaster) indicates that For
149 able system, we expressed the human DISC1 in fruit flies (Drosophila melanogaster).
150 d the antennal movement from tethered flying fruit flies (Drosophila melanogaster).
151 ystem (ALTOMS) for studying social memory in fruit flies (Drosophila melanogaster).
152 al motion and shape wing steering efforts in fruit flies (Drosophila).
153 asm, which contributes to embryo polarity in fruit flies (Drosophila).
154 d stability of bacterial colonization in the fruit fly (Drosophila melanogaster) gut.
155 o knock down gene expression in complex I in fruit fly (Drosophila melanogaster) neurons resulted in
156 ntegrin (the alphaPS3 integrin, scab) in the fruit fly (Drosophila melanogaster) suggests that gastru
157                     In human (Homo sapiens), fruit fly (Drosophila melanogaster), and yeast (Saccharo
158                                              Fruit flies, Drosophila melanogaster, can perform this f
159 essed in a subset of foreleg neurons in male fruit flies, Drosophila melanogaster, rapidly and revers
160 chanism is highly reminiscent of that of the fruit fly, Drosophila melanogaster Altogether, our work
161 etary protein after modest starvation in the fruit fly, Drosophila melanogaster, and identified trypt
162 ts the community of researchers that use the fruit fly, Drosophila melanogaster, as a model organism.
163                                       In the fruit fly, Drosophila melanogaster, aversive olfactory l
164 nvestigate the temperature preference of the fruit fly, Drosophila melanogaster, during infection wit
165      We used replicated genetic lines in the fruit fly, Drosophila melanogaster, each characterized b
166                                          The fruit fly, Drosophila melanogaster, exhibits consolidate
167                    The developing eye of the fruit fly, Drosophila melanogaster, has become a premier
168                                          The fruit fly, Drosophila melanogaster, has helped us to und
169                           Research using the fruit fly, Drosophila melanogaster, has helped us unders
170                                          The fruit fly, Drosophila melanogaster, has proven to be a v
171                                          The fruit fly, Drosophila melanogaster, is well poised as a
172                                       In the fruit fly, Drosophila melanogaster, mating and the recei
173                                       In the fruit fly, Drosophila melanogaster, Pax6 also functions
174                                       In the fruit fly, Drosophila melanogaster, photoreceptors R7 an
175      Here, we show that akin to mammals, the fruit fly, Drosophila melanogaster, prefers food with a
176                   In this study, we used the fruit fly, Drosophila melanogaster, to investigate how i
177                                    Using the fruit fly, Drosophila melanogaster, we found that sustai
178 rXs) Or10a, Or22a, and Or71a from the common fruit fly, Drosophila melanogaster, were recombinantly e
179 ageing have come from studying hearts of the fruit fly, Drosophila melanogaster.
180 (TpnC) genes that are expressed in the adult fruit fly, Drosophila melanogaster: TpnC4 is predominant
181 LDI-MS) is used to image brain lipids in the fruit fly, Drosophila, a common invertebrate model organ
182 highly conserved central brain region in the fruit fly, Drosophila, during flight.
183 we also pay particular attention to the tiny fruit fly, Drosophila, where new tools are creating new
184        Communication between male and female fruit flies during courtship is essential for successful
185 hat no viral-derived piRNAs were produced in fruit flies during different types of viral infection.
186                Spatial patterns in the early fruit fly embryo emerge from a network of interactions a
187 ia, whole-mount nematode larvae, whole-mount fruit fly embryos, whole-mount sea urchin embryos, whole
188 is required for the development of the adult fruit fly epidermis.
189                                              Fruit flies evolved in tropical regions under stable lig
190 en a choice among blue, green and dim light, fruit flies exhibit an unexpectedly complex pattern of c
191 ate hemizygosity of the X chromosome in male fruit flies, expression of X-linked genes increases twof
192 etermining the natural origin of Tephritidae fruit flies for which only the wing is suitable for anal
193      Before consenting to copulate, a female fruit fly gauges both her mating status and her suitor's
194                 The Drosophila melanogaster (fruit fly) gene Diap1 encodes a protein referred to as D
195       Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination.
196 roach that combines Drosophila melanogaster (fruit fly) genetics with transcriptome analyses it was f
197                Single-cell RNA sequencing in fruit flies gives an unprecedented picture of how new ge
198 rganizational principles governing how dirty fruit flies groom their bodies with sequential movements
199 ies constructed from the core members of the fruit fly gut microbiota.
200 ay from the mushroom bodies in the brains of fruit flies has improved our understanding of the ways i
201                                 However, the fruit fly has been exploited to recapitulate PD gene rel
202 osophila melanogaster, commonly known as the fruit fly, has been instrumental in genetics research an
203               To survive these environments, fruit flies have adapted mechanisms of tolerance that al
204                           Genetic studies in fruit flies have implicated the chromatin remodeling com
205 s of the Central Complex in the brain of the fruit fly have identified neurons with activity that tra
206 errets, rabbits, pigs, sheep, zebrafish, and fruit flies, have all been used to model CF disease.
207 s virus replication in both female wasps and fruit fly hosts.
208 city in human cells and neurodegeneration in fruit flies, impairing eclosion and decreasing life span
209                              To determine if fruit flies implement filtering driven by background opt
210    We probed the behavior of male and female fruit flies in a circular arena as individuals and withi
211 ependent phenotypes in both larvae and adult fruit flies, including locomotor activity, degeneration
212 porter-ameliorated HD-relevant phenotypes in fruit flies, including neurodegeneration and life expect
213  exists in the chordate amphioxus and in the fruit fly, indicating that a core MHC region predated th
214  systems, the long germband embryogenesis of fruit flies is an evolutionary derived state restricted
215 pase-9 in mammals or its ortholog, Dronc, in fruit flies, is facilitated by a multimeric adaptor comp
216                   Drosophila melanogaster, a fruit fly, is an exquisite model organism to understand
217                                           In fruit flies, juvenile hormone (JH) induces intestinal st
218 tigate which of the only 10,000 neurons of a fruit fly larva can tip the balance in this trade-off, a
219 ges in most organisms is challenging; even a fruit fly larva has ~50,000 cells and a small mammal has
220  normal corrective response displayed by the fruit fly larva when turned upside down (self-righting).
221  modeling to study how the nervous system of fruit fly larvae processes sensory information to contro
222  controls the muscle contractions that allow fruit fly larvae to crawl.
223 irst time, accumulation of hydrazine in live fruit-fly larvae using epifluorescence microscopy.
224          The finding was made in Drosophila (fruit fly) larval motor neurons through a combined phara
225 udy of DNA protection in active chromatin of fruit fly, leading to a conclusion that the three PANS a
226                                        For a fruit fly, locating fermenting fruit where it can feed,
227                                              Fruit flies love foods containing yeast.
228                                              Fruit fly males exhibit an elaborate courtship display t
229                                           In fruit flies, males sing to court females.
230                            The Mediterranean fruit fly (medfly), Ceratitis capitata, is a major destr
231      To analyze these data in the context of fruit fly metabolic networks, we developed Flyscape, an
232  protection conferred by TDO inhibition in a fruit fly model of Huntington's disease and that TRP tre
233 e used systematic behavioral measurements of fruit fly motion perception to show how flies combine lo
234                               Finally, using fruit fly, mouse and macaque connectomes, we provide fur
235 ce of all stereotyped behaviors performed by fruit flies moving in a shallow arena.
236 dult muscle precursors (AMPs), the transient fruit fly muscle stem cells.
237  eukaryotic species-humans, mice, zebrafish, fruit flies, nematodes, and budding yeast.
238                                              Fruit fly neuroblasts can either self-renew, rest or tak
239                 In the ventral nerve cord of fruit flies, neurons from the same hemilineage use the s
240                       We discovered that the fruit fly olfactory circuit solves this problem with a v
241 e, we follow known circuit mechanisms in the fruit fly olfactory system to derive a simple algorithm
242 interneurons in the first brain relay of the fruit fly olfactory system.
243                                       In the fruit fly, one of the gluconeogenic genes, glucose-6-pho
244                         We show that in male fruit flies, onset of the daytime siesta is delayed by a
245                                       In the fruit fly optic lobe, T4 and T5 cells represent the firs
246 earchers have documented the presence of the fruit fly or Drosophila melanogaster on alcohol-containi
247 tural pest Ceratitis capitata (Mediterranean fruit fly, or Medfly), we identified a Y-linked gene, Ma
248 iate in vitro with Hrp38/Hrb98DE/CG9983, the fruit fly ortholog of the human hnRNP A1/A2 factors.
249 ning monoubiquitin in vivo We found that the fruit fly orthologue of USP5 has catalytic preferences s
250 allenges we advance a comprehensive model of fruit fly OSNs as a cascade consisting of an odorant tra
251 ysis to quantify the probing behavior of the fruit-fly parasitoid Diachasmimorpha longicaudata (Braco
252 any metazoan species including human, mouse, fruit fly, planaria and flowering plants.
253                     Thus, the nonluminescent fruit fly possesses an inherent capacity for bioluminesc
254                                The larvae of fruit flies produce pheromones to control whether they a
255 ndings together with experimental results on fruit flies' reaction time and sensory motor reflexes, w
256 tiation promoters are pervasive in human and fruit fly, reflecting evolutionary conservation.
257 clin B3 homologues from frog, zebrafish, and fruit fly rescue meiotic progression in cyclin B3-defici
258 roups of insects-crickets, grasshoppers, and fruit flies-reveals common strategies for extracting eth
259         Understanding the logic behind how a fruit fly's brain tells it to groom its body parts in a
260                We found that fungus-infected fruit flies seek out cooler temperatures, which facilita
261                     Learning based on what a fruit fly sees or what it smells might not involve disti
262 d sensory motor reflexes, we conjecture that fruit flies sense their kinematic states every wing beat
263 hey are also involved in taste perception in fruit flies, significantly expanding their scope of acti
264 ver chasms larger than step size is vital to fruit flies, since foraging and mating are achieved whil
265                           A newly-identified fruit fly sleep-regulator is also an AMP.
266 new study by Berry et al. indicates that, in fruit flies, sleep accomplishes this in part by preventi
267 2 Zeugodacus cucurbitae; three invasive pest fruit fly species with overlapping hostplants.
268 ed several billion small RNA reads across 12 fruit fly species.
269   Here we show that Drosophila melanogaster (fruit fly) subject to obesogenic challenges exhibits met
270 ficities function in cell types not found in fruit flies, suggesting that evolution of TF specificiti
271                               A new study in fruit flies suggests modulation of neural activity links
272 the eye and its target neuropils in fish and fruit flies supports a homology between some core elemen
273                       Inhibition of Nuak1 in fruit flies suppressed neurodegeneration in tau-expressi
274                   During pathogen infection, fruit fly survival varies directly with sleep.
275 hange in the temperature preference of adult fruit flies that results from a shift in the relative co
276 f Wolbachia wMelPop (a bacterial symbiont of fruit flies) that differed in copy number of a region of
277                                       In the fruit fly, the large lateral ventral neurons (lLNvs) are
278 ntified motor neurons control flexion of the fruit fly tibia.
279 kappaB plays a central role in immunity from fruit flies to humans, and NF-kappaB activity is altered
280 tate motion by a wide range of animals, from fruit flies to humpback whales, operating in either air
281               We find a conserved role, from fruit flies to mammals, for L-type calcium channels in a
282 inds that viewing small spots causes walking fruit flies to stop in their tracks, and identifies the
283 ge tracing and genetic analysis in the adult fruit fly to gain new insight into the cellular and mole
284 that are conserved in orthologs ranging from fruit fly to human.
285 cts that replace native introns of human and fruit fly tRNA genes with the Broccoli fluorescent RNA a
286  a novel stimulus that initially interests a fruit fly turns into a familiar one.
287  have measured the temperature preference of fruit flies under different pathogen conditions.
288 e apply CNEr to two novel genome comparisons-fruit fly vs tsetse fly, and two sea urchin genomes-and
289                    From studies beginning in fruit flies, we now know that circadian regulation perva
290 ned families of the Ig superfamily (IgSF) in fruit flies were discovered to label different subsets o
291 Dissected wings from Drosophila melanogaster fruit flies were used as the hydrophobic, laser energy s
292 ntegration required for odor localization in fruit flies, which may be representative of adaptive mul
293 leep-dependent slow wave oscillations in the fruit fly, which act to inhibit sensory input during sle
294 undly suppresses aggressive behaviors in the fruit fly, while other social behaviors are unaffected.
295                       A mature virgin female fruit fly will initially resist copulation, while she as
296 n aerodynamic forces, and furthermore that a fruit fly, with nearly massless wings, would not exhibit
297 ed our motif database for human, mouse, rat, fruit fly, worm, yeast and Arabidopsis, and curated larg
298                 Pch2 homologs are present in fruit flies, worms, and mammals, however the molecular m
299 namics of volumes of neurons and synapses in fruit flies, zebrafish larvae, mice and ferrets in vivo.
300 mensional, terabyte-sized image data sets of fruit fly, zebrafish and mouse embryos acquired with thr

 
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