ライフサイエンスコーパス: functional characterization of

1 Functional characterization of 1 novel variant, E141G-Ca

2 Here we present a functional characterization of 2.5 A and 3.25 A X-ray cr

3 synthesis, via native chemical ligation, and functional characterization of (24-108)MDMX and its Tyr9

4 Biochemical and functional characterization of 36 of these novel DeltaB7

5 Comprehensive functional characterization of 96 gliomas by genome-wide

6 We describe the structural and functional characterization of a 237 residue deacetylase

7 This identification and functional characterization of a cnidarian peptide GPCR

8 inding provides, to our knowledge, the first functional characterization of a eukaryotic member of a

9 Here we report the functional characterization of a glycine-rich proline-ri

10 Here, we describe the identification and functional characterization of a highly specific, regula

11 ere we provide a biochemical/biophysical and functional characterization of a human monoclonal alloan

12 Here, we performed a complete functional characterization of a lncRNA that harbors a s

13 Here, we report the functional characterization of a maize NIN-like protein

14 Here we report the functional characterization of a nodule-specific Suc tra

15 Here, we report the structural and functional characterization of a novel ATPase, Sulfolobu

16 Here, we report the isolation and functional characterization of a novel cis-prenyl diphos

17 G12D)-driven lung cancer model, we performed functional characterization of a panel of tumour suppres

18 report describes to our knowledge the first functional characterization of a plant HGO gene, defects

19 In this study, we report the functional characterization of a plant-specific basic he

20 We report here the sequence and functional characterization of a recombinantly expressed

21 Cloning and functional characterization of a representative set of t

22 Here, we report the identification and functional characterization of a rice epigenetic repress

23 Functional characterization of a subset of GRIN2A mutant

24 Herein we report the bioinformatic and functional characterization of a T6SS-like pathway in di

25 Here, we report the functional characterization of a zinc finger transcripti

26 entification and biochemical, structural and functional characterizations of a novel single-chain (12

27 igh-resolution expression map and a detailed functional characterization of A2AR-CB1R heteromers in t

28 We report the isolation and functional characterization of AaTXKbeta(2)(-)(6)(4), a

29 ularly focusing on the precise molecular and functional characterization of aberrant MDS stem cells i

30 Furthermore, phenotypic and functional characterization of adoptively transferred ce

31 y performing an exhaustive immunological and functional characterization of adult nerve-derived human

32 t genetic system facilitates high-throughput functional characterization of algal genes and accelerat

33 complete thermal, structural, mechanical and functional characterization of all nano-biocomposites wa

34 ot only accurate discovery, but also for the functional characterization of altered alleles.

35 This marks the functional characterization of an endogenous growth fact

36 We report the in vitro and in vivo functional characterization of an ent-kaurene synthase o

37 Functional characterization of an identified novel alter

38 Here we report the identification and functional characterization of an important component of

39 In this article, we report the functional characterization of an mAb that recognizes a

40 We report the functional characterization of an orphan gene (Triticum

41 Here, we report the functional characterization of another PAT, AtPAT21, dem

42 rnate targets for addiction medicine through functional characterization of anti-relapse mechanisms.

43 ata resource that can aid the biological and functional characterization of ASB ubiquitin ligases.

44 However, functional characterizations of auxin-related genes in e

45 Here, we describe the biochemical and functional characterization of Avena sativa phytochrome

46 from a systematic strategy enabling a joint functional characterization of bacterial methylomes by t

47 Taken together, our functional characterization of BHTC links defense regula

48 Molecular and functional characterization of BMSC-induced hormone inde

49 Advances in the sequencing and functional characterization of both pathogen and host ge

50 f a bacterial homolog (KpBest) of hBest1 and functional characterizations of both channels.

51 in, we report the biochemical properties and functional characterization of BPSS2242 from B. pseudoma

52 omic profiling of cancer cell lines and from functional characterization of cancer cell dependencies,

53 road utility of the Degron-KI system for the functional characterization of cancer genes.

54 T/MR imaging for the detection, staging, and functional characterization of cancer, this new technolo

55 across cancer types, the identification and functional characterization of candidate driver genetic

56 g a multi-omics approach in combination with functional characterization of candidate genes both in v

57 Identification and functional characterization of candidate regulators acti

58 efit from having a standardized platform for functional characterization of candidate variants in the

59 Accordingly, we focused on the functional characterization of CCN6 and CCN6 mutants.

60 Functional characterization of CD47 in sorafenib-resista

61 We reported the functional characterization of cDNAs encoding short-chai

62 Functional characterization of ClVST1 provides a novel s

63 Here we report the functional characterization of CnPpz1 (CNAG_03673) and t

64 which was instrumental in the structural and functional characterization of CntM and confirmed its op

65 Here we report on the functional characterization of components of a potential

66 In this study, we report the functional characterization of CONSERVED ONLY IN THE GRE

67 fort has gone towards the identification and functional characterization of CREs and associated epige

68 Herein, we report the functional characterization of CsBGlu12, a beta-glucosid

69 This in vitro approach to functional characterization of CSCs and their differenti

70 Functional characterization of cse4 phosphorylation muta

71 However, functional characterization of CYPs has been challenging

72 ssays with WRC tissue extracts, cloning, and functional characterization of cytochrome P450 monooxyge

73 Functional characterization of diatom EukCatAs indicates

74 iew discusses new findings in phenotypic and functional characterization of different subsets of macr

75 Mean outcome was the morphologic and functional characterization of different subtypes of mac

76 Here we report a structural and functional characterization of dihydroxyacid dehydratase

77 provements in both diagnostic strategies and functional characterization of disease mechanisms.

78 der and schizophrenia.SIGNIFICANCE STATEMENT Functional characterization of disease-associated varian

79 Functional characterization of distinct inhibitory neuro

80 recent curation effort focuses on providing functional characterizations of distinct subfamily archi

81 that has been made in the identification and functional characterization of DNA sequence variants ass

82 Functional characterization of DNMT3A-H3 tail-p53 or -TD

83 ong with integrated expression profiling and functional characterization of drug-resistant and engine

84 Here we report the functional characterization of EFA6R.

85 In this report, we describe the first functional characterization of EhMIF.

86 dic droplets and apply it to high-throughput functional characterization of enzymes that convert hydr

87 e and biological context, and is powerful in functional characterization of experimental and clinical

88 Functional characterization of fibroblasts derived from

89 Here, we report the functional characterization of four CfTPSs using in vitr

90 Functional characterization of four selected missense mu

91 candidates and enlarging the toolbox for the functional characterization of gene regulation in the hi

92 facilitates the fine-mapping and subsequent functional characterization of genes and networks causin

93 on the recent progress made on isolation and functional characterization of genes encoding biosynthet

94 to cure those that are afflicted, rely upon functional characterization of genes essential to the pa

95 and show that this grouping could facilitate functional characterization of genes in these families.

96 strains have recently become available, the functional characterization of genes is significantly la

97 We performed an exhaustive functional characterization of genetic variants associat

98 iours, and provide a general approach to the functional characterization of genetically identified su

99 neurons have prevented a more comprehensive functional characterization of ghrelin-responsive neuron

100 in combination with PET imaging studies for functional characterization of GLUTs in BC.

101 We here report the functional characterization of GmBZL2 (relatively highly

102 Future large-scale studies with functional characterization of GWAS findings are warrant

103 In this study, we report the functional characterization of heterotrimeric G-proteins

104 is surprising that a detailed structural and functional characterization of hGMPK is lacking.

105 r both the identification and structural and functional characterization of homologous proteins from

106 he past decade, molecular identification and functional characterization of host factors in the virus

107 The structural and functional characterization of human enzymes that are of

108 lar composition of GTEx tissues enabling the functional characterization of human genetic variation t

109 Independent functional characterization of human Th1, Th2, Th17, T f

110 esults provide the so-far most comprehensive functional characterization of human tRNAs with intricat

111 Here we report the crystal structure and functional characterization of human Wapl.

112 dge generated through sequencing efforts and functional characterization of identified (epi-)genetic

113 scovery efforts are transitioning toward the functional characterization of implicated genetic variat

114 While identification and functional characterization of in vivo phosphorylation s

115 Functional characterization of individual cells within h

116 The discovery and functional characterization of individual driver mutatio

117 llowed, to our knowledge for the first time, functional characterization of LITRs in an autologous sy

118 hod protocol for the annotation and detailed functional characterization of lncRNAs within the genome

119 les lie between transcriptome sequencing and functional characterization of lncRNAs: identifying trul

120 Here we provide an in-depth functional characterization of LytB, the peptidoglycan h

121 ent reverse genetics platforms to facilitate functional characterization of M. truncatula genes.

122 Though its genome has been sequenced, functional characterization of many Ae. aegypti genes, p

123 ith those of related herpesviruses has eased functional characterization of many MDV genes.

124 that led ultimately to the cDNA cloning and functional characterization of many of today's best-know

125 present the first data on identification and functional characterization of Mate proteins in zebrafis

126 Here we perform the first in-depth functional characterization of mechanisms driving CIN in

127 and transmitted by membrane-bound proteins, functional characterization of membrane-associated NAC t

128 The identification and functional characterization of microbial communities rem

129 hes and will facilitate rapid and systematic functional characterization of microbial genomes.

130 Here we describe the first receptor-level functional characterization of mitragynine and related n

131 Notably, functional characterization of model interface domain mu

132 This work completes the structural and functional characterization of mono- and di-domain ARO/C

133 the discovery, biosynthesis, elicitation and functional characterization of monocot terpenoid phytoal

134 Our results provide a functional characterization of mossy cells in the behavi

135 Phenotypic and functional characterization of MR1T cell clones showed m

136 eported herein should prove of value for the functional characterization of MTs, MT complexes, and MT

137 transferases (MTases) permitted not only the functional characterization of multiple, yet undescribed

138 eport here the expression, purification, and functional characterization of murine IFN (mIFN).

139 chanism, we present cryo-EM structures and a functional characterization of murine Slc26a9.

140 Functional characterization of mutant FHF2A co-expressed

141 the best of our knowledge, this is the first functional characterization of mutant FOS proteins found

142 Functional characterization of mutant Slo2 channels sugg

143 Here, we report the presence and functional characterization of mutations in the transcri

144 Functional characterization of naturally occurring DNA p

145 MAIThi congenic strain allows phenotypic and functional characterization of naturally occurring mouse

146 TEC domain will facilitate the discovery and functional characterization of new T6SS effectors in Gra

147 the utility of high-throughput screening for functional characterization of noncoding DNA and reveal

148 Functional characterization of noncoding sequences is cr

149 ) that provides a versatile approach for the functional characterization of novel cancer genes and ad

150 Here we report on the identification and functional characterization of novel IDS-like TPSs (ILTP

151 ffers an advantage in the identification and functional characterization of novel RNA isoforms and RN

152 Functional characterization of OFF-RGC terminals in tect

153 Here, we first describe functional characterization of ORF131b (gp17) and ORF436

154 Collectively, the functional characterization of P1 HA-elicited mAbs sheds

155 phenotype of HCN1-deficient mice, a detailed functional characterization of pacemaker mechanisms in s

156 We further carried out functional characterization of pairs of class-I and -II

157 Functional characterization of patient fibroblasts showe

158 Functional characterization of patients' fibroblasts and

159 We present here a functional characterization of PcalRG, a novel reverse g

160 Functional characterization of pCRY was performed based

161 DG PET/CT is useful for the localization and functional characterization of pheochromocytomas and par

162 which mitochondria can accumulate Ca(2+), a functional characterization of plant MCU homologs has be

163 A detailed phenotypic, functional characterization of plasma markers and immune

164 We report here the positional cloning and functional characterization of Pm41, a powdery mildew re

165 rmed an extensive anatomical, molecular, and functional characterization of prominent DA transgenic m

166 cale proteomic methods are essential for the functional characterization of proteins in their native

167 ole in the identification and structural and functional characterization of proteins.

168 Here, we report the first functional characterization of PRX17 (At2g22420), one of

169 Functional characterization of PTP1BDelta6 revealed a po

170 somatic genome engineering approach enables functional characterization of putative cancer genes in

171 Here, we report the map-based cloning and functional characterization of qFIRM SKIN 1 (qFIS1), a m

172 This study reports the isolation and functional characterization of rainbow trout (Oncorhynch

173 Functional characterization of rare variants of uncertai

174 These results provide useful functional characterization of RBM47 and direct biochemi

175 However, the functional characterization of RD3 in tumor systems has

176 Yet, the topological and functional characterization of real GRNs is often still

177 Functional characterization of recombinant CYP6P9b confi

178 Functional characterization of REM1.3 revealed that it i

179 Functional characterization of representative GTPBP1-lik

180 The genomics-enabled functional characterization of responses to the challeng

181 Here, we describe the functional characterization of RISAP, a RAC5 effector id

182 Functional characterization of SCN10A variants was perfo

183 The identification and functional characterization of secreted effectors and th

184 The identification and functional characterization of Si transporters can be ex

185 The molecular and functional characterization of single cells at scale has

186 date have been directed toward discovery and functional characterization of single disease-causing va

187 lassification of neuronal cell types and the functional characterization of single neurons, we presen

188 Functional characterization of single nucleotide variant

189 and adults and provide a basis for detailed functional characterizations of single zebrafish Mate tr

190 Functional characterization of site-directed mutants tar

191 lvement of MMPs was addressed by cloning and functional characterization of Sl2-MMP and Sl3-MMP from

192 Here, we present the functional characterization of Sm protein E1 (SME1), an

193 Here we report the genetic and functional characterization of somatic mutations affecti

194 we conduct a phenotypic, transcriptomic, and functional characterization of SP and SP-derived EVs fro

195 owerful tools for the unbiased discovery and functional characterization of specific genetic elements

196 However the functional characterization of specific instances remain

197 gle domains and are therefore unsuitable for functional characterization of specific kringle domains.

198 Spiking statistics and our functional characterization of spikelet activity indicat

199 omes how can we accelerate the discovery and functional characterization of sRNAs in diverse organism

200 ectious disease agents may be debatable, the functional characterization of such antibodies represent

201 Together, the subcellular localization and functional characterization of SYT1 highlights a putativ

202 f this study was to provide a phenotypic and functional characterization of TANs in surgically resect

203 Functional characterization of Tet proteins has been com

204 Functional characterization of Tet TKO ESCs revealed a r

205 ichiometry using single subunit counting and functional characterization of tetrameric concatemers.

206 Functional characterization of the 40%-identical ortholo

207 ledge, high-resolution taxonomic and protein functional characterization of the ancient oral microbio

208 The production, crystal structure, and functional characterization of the C-terminal cysteine-r

209 he models may provide useful information for functional characterization of the candidate lncRNAs ass

210 Structural and functional characterization of the candidates resulted i

211 irectly from native nanodiscs, which enables functional characterization of the channel by electrophy

212 from Xenopus tropicalis (XtOTOP3) along with functional characterization of the channel.

213 Functional characterization of the disease gene revealed

214 Here, we present the functional characterization of the effector See1 (Seedli

215 Functional characterization of the encoded microproteins

216 We describe here the identification and functional characterization of the enzyme O-GlcNAcase (O

217 Here, we describe the gene discovery and functional characterization of the final two enzymes of

218 Functional characterization of the FPGS mutants showed t

219 Here, we report the purification and functional characterization of the full-length Red1 prot

220 Functional characterization of the GCM2 variants and del

221 Here, we report the functional characterization of the GG motif using MoaA,

222 The functional characterization of the GPCR interactome has

223 spite significant progress in structural and functional characterization of the Hsp70 proteins fundam

224 Here we report on the functional characterization of the hypothetical protein

225 s unprecedented resolution for taxonomic and functional characterization of the intestinal microbiota

226 For a full functional characterization of the L176F mutant we expre

227 ic analyses and an exhaustive phenotypic and functional characterization of the lymphocyte compartmen

228 n lantibiotics, and serve as a basis for the functional characterization of the many lantibiotic-like

229 In this work, we present the functional characterization of the Medicago truncatula S

230 This review discusses the functional characterization of the microbiome, highlight

231 udy we performed a genetic, biochemical, and functional characterization of the moss Physcomitrella p

232 Functional characterization of the most highly mutated D

233 Functional characterization of the mouse genes, hence, h

234 Functional characterization of the mutants demonstrated

235 entation when a only partial topological and functional characterization of the network is available.

236 vided useful resources and tools for further functional characterization of the niche in the future.

237 nstrained randomizations do not preserve the functional characterization of the nodes in the referenc

238 Functional characterization of the Pennycress FAE1 enzym

239 We present here a structural and functional characterization of the PerR from the pathoge

240 identity, were expressed in Escherichia coli Functional characterization of the purified recombinant

241 regulators, taking advantage of the detailed functional characterization of the regulatory region of

242 Here, we present a functional characterization of the seven SEP/AGL6 and fo

243 Functional characterization of the shrew sodium taurocho

244 vide an unambiguous structural, dynamic, and functional characterization of the supramolecular BCPs.

245 Performing functional characterization of the two evolutionarily co

246 evelopment of these phenotypes, we performed functional characterization of the zebrafish and Drosoph

247 Structural and functional characterization of these antibodies will inf

248 Structural and functional characterization of these assemblies requires

249 gar production and glycan formation, but the functional characterization of these enzymes and the ful

250 This is the first example of functional characterization of these JadX-like proteins,

251 Biochemical and functional characterization of these models revealed tha

252 Functional characterization of these mutations demonstra

253 Functional characterization of these mutations showed ab

254 However, the functional characterization of these QTLs has been limit

255 sease-associated variants are non-coding and functional characterization of these signals requires kn

256 Functional characterization of these target antigens rev

257 In planta functional characterization of these TPS enzymes showed

258 Functional characterization of these two lineages of CD1

259 Functional characterization of these two O-methyltransfe

260 e colocalization analyses were inconclusive, functional characterization of these variants provided t

261 process that limits detailed structural and functional characterization of this important class of p

262 inhibitor, DCLK1-IN-1, developed to aid the functional characterization of this important kinase.

263 The genomic and functional characterization of this plasmid showed a com

264 Here we complete the functional characterization of this protein family by de

265 A detailed functional characterization of this substitution is lack

266 However, functional characterization of those fields has been lar

267 al process, and molecular function, enabling functional characterization of thousands of proteins.

268 re, we describe an unbiased platform for the functional characterization of thousands of variants of

269 e we report the transcriptional profiles and functional characterization of three An. gambiae IR (AgI

270 re we carried out comparative structural and functional characterizations of three cellulose-active C

271 TATL-seq are useful tools for annotation and functional characterization of TLs, and can be applied t

272 In this paper, we report on the functional characterization of tobacco (Nicotiana tabacu

273 Functional characterization of transcripts specific to d

274 Assay (OSTA), should greatly facilitate both functional characterization of transporters as well as h

275 Numerous examples of the structural and functional characterization of transporters, ion channel

276 Functional characterization of TSHR mutants confirms the

277 Functional characterization of tumor-associated gammadel

278 Here, we report the identification and functional characterization of two AGAMOUS (AG)-like MAD

279 Functional characterization of two bed bug odorant recep

280 We describe the structural and functional characterization of two functionally coupled

281 Here, we report the identification and functional characterization of two Golgi-localized exo-b

282 Here, we present a structural and functional characterization of two neutralizing antibodi

283 Functional characterization of two orthologs from the di

284 We report here the discovery and functional characterization of two S. divinorum diterpen

285 y analyses, we report the identification and functional characterization of two trypanosome-specific

286 Here, we report the functional characterization of two type I MADS box TFs i

287 We present the functional characterization of type B Ggamma subunit (Sl

288 Here we report the identification and functional characterization of UAS homologs from avascul

289 we report a design, synthesis, and detailed functional characterization of unique strongly biased al

290 Functional characterization of unknown genes is a challe

291 his communication reports the structural and functional characterization of urotoxin, the first K(+)

292 structural model not only offers an improved functional characterization of V1 neurons, but also prov

293 These results suggest that functional characterization of variants within MODY gene

294 The structure of SubAB and the accompanying functional characterization of various mutants of SubAB

295 We report the identification and functional characterization of VGCC beta-anchoring and -

296 Therefore, the identification and functional characterization of viral genetic determinant

297 Therefore, the identification and functional characterization of viral genetic factors imp

298 Functional characterization of virion-associated host fa

299 Functional characterization of WsMYC2 via artificial mic

300 /Deltaex13mice, we provide the first in vivo functional characterization of ZC3H14 as a regulator of