ライフサイエンスコーパス: fusion

1 nting structural rearrangements required for fusion.

2 recedes pyrrole annulation and bicyclic ring fusion.

3 in assembly is sufficient to drive cell-cell fusion.

4 membrane tethering, facilitating docking and fusion.

5 insert into the endosomal membrane and drive fusion.

6 that regulate plant hybridization and gamete fusion.

7 ls, playing a critical role in mitochondrial fusion.

8 stress conditions, s-OPA1 is dispensable for fusion.

9 residue peptide drug that inhibits HIV entry/fusion.

10 n mouse macrophages undergoing IL-4-mediated fusion.

11 efore rearrangement, corresponding to slower fusion.

12 d that alpha(2)M* induced trophoblastic cell fusion.

13 in protein play a critical role in achieving fusion.

14 ulator gH/gL complex, triggering gB to drive fusion.

15 L MAbs to block binding to gD and/or inhibit fusion.

16 and mechanisms regulating trophoblastic cell fusion.

17 h the processes of mitochondrial fission and fusion.

18 allowing calcium entry to initiate lysosome fusion.

19 mote stalk widening, curvature, and eventual fusion.

20 deformation may contribute to Ca(2+)-induced fusion.

21 Interestingly, the network does not undergo fusion.

22 ons describe a mechanism for gating membrane fusion.

23 ments through which the HA mediates membrane fusion.

24 ential for proper palate shelf elevation and fusion.

25 osely and readily rearrange, leading to fast fusion.

26 ivates the fusogen gB, resulting in membrane fusion.

27 at telomeres, resulting in frequent telomere fusions.

28 e tumors harbored FGFR1-3 point mutations or fusions.

29 methods for feature selection and multimodal fusion, 3) greater emphasis on algorithms' ability to ca

30 from a pre-hairpin intermediate to its post-fusion 6-helical bundle state.

31 ies and review the strategy of cell membrane fusion, a recent strategy for direct delivery of protein

32 Fusion activation after receptor binding is proposed to

33 We suggest this loop confers fusion activation and entry properties more in line with

34 To explore requirements for gB's fusion activity, we generated a set of chimeras composed

35 V gH/gL does not utilize a similar motif for fusion activity.

36 rying the relative rates of vesicle budding, fusion and biochemical conversion.

37 The clinical correlation found that the Fusion and BioFire assays had a positive percent agreeme

38 In addition, the Fusion and BioFire assays showed better clinical perform

39 M5 deletion leads to increased mitochondrial fusion and decreased mitochondrial turnover.

40 endosome(9), are necessary for the membrane fusion and delivery of RNA from exo-HAV into the cytopla

41 drial safeguard, that adjusts the balance of fusion and division in response to increased mitochondri

42 LZTR1 affects the dynamics of fusion and fission of recycling endosomes by controlling

43 e of different processing technologies, data fusion and PARADISe presented advantages, since a more c

44 ndependent of their known roles in homotypic fusion and protein sorting (HOPS)-mediated vesicle tethe

45 N(50-54)) motif is important for higher KSHV fusion and that EBV gH/gL does not utilize a similar mot

46 n general understanding of stimuli-triggered fusion and the development of synthetic fusogens for bio

47 ent of the endolysosomal tethering homotypic fusion and vacuole protein sorting (HOPS) complex, was r

48 cuoles including SNAREs, the HOPS (homotypic fusion and vacuole protein sorting) tethering and SNARE-

49 x virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis.

50 ational change needed to facilitate membrane fusion and virus infection, and the epitope recognized b

51 og gene-intergenic and intergenic-intergenic fusions and characterize their impact.

52 e potential oncogenic function of intergenic fusions and highlight the wide-ranging consequences of s

53 ent of patients with tumours harbouring NTRK fusions and MMR deficiencies, respectively, regardless o

54 che Cobas, Abbott m2000, and Hologic Panther Fusion) and 167 to 511 copies/ml for sample-to-answer (D

55 etal development, viral infection, cell-cell fusion, and ataxia.

56 ve cell migration, large-scale actin-network fusion, and purse-string contraction orchestrate to rest

57 ge response that lacks accompanying telomere fusions, and propagate for multiple generations.

58 Although powerful, the intein fusion approach suffers from premature hydrolysis and lo

59 In this work, we propose a data fusion approach that exploits the integration of complem

60 Mitochondrial fission and fusion are highly regulated by energy demand and physiol

61 Vesicle tethering and fusion are thought to occur sequentially, with tethering

62 mplification and activating MET mutations or fusions are all now known to be drivers of oncogenesis.

63 alterations, such as translocations and gene fusions, are often cancer drivers.

64 Finally, recognition of gene fusions as a driving mechanism in neoplasia has led to d

65 -of-addition studies, transient cell-to-cell fusion assays, and chimeric vesicular stomatitis virus (

66 dynamic control of COPI budding and vesicle fusion at the rims.

67 We report fusions at MYC and a neighboring gene, PVT1, which are r

68 Children with ABL-class fusion B-cell acute lymphocytic leukaemia have poor outc

69 tcomes of paediatric patients with ABL-class fusion B-cell acute lymphocytic leukaemia in the pre-tyr

70 es spontaneous release without affecting the fusion barrier.

71 These fusion-based estimates can be a valuable resource when a

72 We used molecular dynamics simulations of fusion between a full-length hemagglutinin proteoliposom

73 el interpretation took advantage of the data fusion between atomic and molecular spectra in order to

74 not affect the response to odorants, whereas fusion between chemoattractive and chemorepulsive neuron

75 We demonstrate that fusion between chemoattractive neurons does not affect t

76 ully differentiated neural cells, indicating fusion between the cancer and neural stem cells.

77 To discover driver fusions beyond canonical exon-to-exon chimeric transcrip

78 ons associated with expressed protein-coding fusions, breakend hypermutation, and acral, but not cuta

79 The chromosome breakage-fusion-bridge (BFB) cycle is a mutational process that p

80 he complex architecture of ecDNA, a breakage-fusion-bridge and other complex rearrangements.

81 y telomere crisis primarily involve breakage-fusion-bridge cycles and simple genome rearrangements ra

82 centric chromosome intermediate and breakage-fusion-bridge cycles that are repaired using multiple di

83 drug selection underwent continuing breakage-fusion-bridge cycles, generating amplicons more than 100

84 odels and prevents alphaSyn-mediated vesicle fusion by altering the conformational properties of the

85 CHK-263 blocks fusion by binding an epitope that spans across E1 and E2

86 The low pH of endosomes activates fusion by facilitating irreversible conformational chang

87 demonstrate how Serinc proteins prevent full fusion by interfering with this process.

88 -cholesterol interaction mediates virus-cell fusion by recruiting gp41 to the boundary of the liquid-

89 cells, which limits the precision with which fusion can be synchronized and controlled, and reconstit

90 Whereas the process of HIV membrane fusion can be tracked by fluorescence microscopy, the 3D

91 SRTs deposited by exogenous, TF-transposase fusions can be used to map TFBS.

92 ariations in motility as well as docking and fusion capability.

93 amyxoviruses cause a second type of membrane fusion, cell-cell fusion (syncytium formation), which is

94 arge number of proteins comprising the entry/fusion complex (EFC), which enables infection of diverse

95 rustrated at acidic pH in both pre- and post-fusion conformations.

96 Here, we describe fusion construct design and characterization (variable t

97 As rates of spinal fusion continue to increase, rates of complications such

98 usions, their pathogenic mechanism, and gene fusion detection methods in lacrimal gland and primary o

99 , with tethering mediated by the exocyst and fusion driven by assembly of soluble NSF attachment prot

100 iotic and biotic stresses and prevents organ fusion during development.

101 so discuss the elusive mechanism of membrane fusion during nuclear pore complex (NPC) biogenesis.

102 Fusion dynamics have been studied by tracking viruses wi

103 1 myoblasts demonstrated delayed and reduced fusion efficiency compared to WT.

104 somal membrane, have a significant impact on fusion efficiency in our models.

105 exposure of the co-receptor binding site and fusion elements.

106 The sensor with a fusion enzyme showed DET to a gold electrode, with a lim

107 Gene fusion events are significant sources of somatic variati

108 To capture fusion events, the process must be curtailed by trapping

109 effector proteins involved in trafficking or fusion events, whereas those at the inner surface are ne

110 g multivesicular body (MVB) trafficking, MVB fusion, exosome uptake and endosome acidification.

111 transcriptional readthrough and lower G and fusion (F) protein levels than for the wild type.

112 o receive a single intramuscular dose of RSV fusion (F) protein nanoparticle vaccine or placebo.

113 ctor chimpanzee-adenovirus-155, encoding RSV fusion (F), nucleocapsid, and transcription antiterminat

114 del carrying a knockout of the mitochondrial fusion-fission-related gene solute carrier family 25 mem

115 l mitochondria show signs of damage, such as fusion/fission defects and vacuolation, but axons do not

116 e molecular machineries involved in membrane fusion/fission have been dissected, regulation of membra

117 ine the structure of a full-length TIR-STING fusion from the Pacific oyster Crassostrea gigas.

118 The Panther Fusion (Fusion; Hologic) system has an array of highly s

119 junction, the duplication allele produces a fusion gene derived from ATAD3A and ATAD3C, the protein

120 A novel fusion gene, generated by genomic rearrangement, MYB-NHS

121 Full annotation of fusion genes aided by the visualization tool based on tw

122 P complex within rattlesnakes, creating both fusion genes and substantially reduced gene complexes.

123 be helpful to study the functional aspect of fusion genes.

124 ver, the function of s-OPA1 in mitochondrial fusion has been debated, because in some stress conditio

125 Identification of canonic gene fusions has led to development of sensitive and specific

126 H at which HA is activated to cause membrane fusion, has been associated with the replication, pathog

127 In addition to diagnostic accuracy, gene fusions have prognostic implications, such as unfavorabl

128 ismatch repair (MMR) deficiencies or NTRK1-3 fusions, have shown considerable activity in clinical tr

129 acid substitutions in hemagglutinin-esterase fusion (HEF) glycoproteins suggests that antigenic drift

130 The Panther Fusion (Fusion; Hologic) system has an array of highly sensitive

131 These fusion hybrids survived for extended times in a quiescen

132 Using inertial confinement fusion (ICF) as a test-bed problem, we model a one-dimen

133 rum RSV-neutralizing antibodies and anti-RSV fusion immunoglobulin G increased >=4-fold in 95% and 10

134 from the right ventricle showed ventricular fusion in 4 out of 5 cases.

135 t protein receptor (SNARE)-mediated membrane fusion in all eukaryotes.

136 such as unfavorable prognosis of PAX3-FOXO1 fusion in alveolar rhabdomyosarcoma.

137 capsulation of invading pathogens, cell-cell fusion in response to foreign bodies, and their self-sac

138 h the capability of the virus to induce cell fusion in the UL24syn background.

139 cytotoxic granule maturation, transport and fusion in vitro with super-resolution imaging techniques

140 nonamers explain the vast majority of tandem fusions in human repertoires.

141 males [50% (4/8)], along with some rare RET fusions, including SLC39A8-RET, ITIH2-RET, FYCO1-RET and

142 Right and noncoronary cusp fusion, increasing AS and AI, and older age were indepen

143 Ectopic expression of BCL2L14-ETV6 fusions induce distinct expression changes from wild-typ

144 pregulated in mouse models and in human YAP1-fusion induced ependymoma, supporting their similarity.

145 Since HIV-1 fusion inhibitor peptides need to be embedded in the mem

146 ter treatment with an autophagosome-lysosome fusion inhibitor, chloroquine, indicating that Rab27b KD

147 ach to design new targeted peptides as HIV-1 fusion inhibitors and lead us to define a retro-enantio

148 This new gene fusion involves exons 1-4 from the 5' end of the Trk fus

149 Somatic chromosomal fusions involving ROS1 produce chimeric oncoproteins tha

150 the tumor microenvironment; and cancer cell fusion is a direct route to tumor cell heterogeneity.

151 Laser powder bed fusion is a dominant metal 3D printing technology.

152 Our studies indicate that Pten-NOLC1 gene fusion is a driver for human cancers.

153 Spectral fusion is a general technique that can fuse spectra reco

154 Using p14 mutants, we demonstrate that fusion is abrogated when binding of an adaptor protein i

155 Our results demonstrate that the FHL2-GLI2 fusion is likely the oncogenic driver of SSTs, defining

156 chanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two forms of Opa1.

157 HOPS-dependent fusion is saturable at low concentrations of each Q-SNAR

158 The TMPRSS2-ERG fusion is the most common genomic rearrangement in human

159 erall stereochemical disposition of its ring fusions is distinct from those of related natural produc

160 radation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting h

161 This is driven by the overexpression of the fusion kinase NPM1-ALK, but the mechanism by which ALK o

162 racterized by the expression of an oncogenic fusion kinase termed BCR-ABL1.

163 led a druggable site formed by the G protein fusion loops that has not previously emerged as a target

164 tures of alloys produced by laser powder bed fusion (LPBF) additive manufacturing (AM) are being repo

165 s instrument was transitioned to an Orbitrap Fusion Lumos instrument.

166 nvolved in these processes are the vesicular fusion machinery (SNARE proteins) and the regulatory pro

167 se EMC subunits also bind to the ER-resident fusion machinery component syntaxin18, which is required

168 Recent evidence suggests that SNARE fusion machinery play critical roles in postsynaptic neu

169 We conclude that antibody-TTR fusions may provide a powerful platform for multimerizin

170 ssion of an upstream or downstream gene by a fusion-mediated repositioning of a regulatory sequence i

171 The flexible fusion method of sum of ranking differences (SRD) is app

172 The feature fusion method statistically significantly outperformed u

173 in depression were identified with the TWAS FUSION method, based on summary statistics from the larg

174 Four BME space/time kriging and data fusion methods were evaluated.

175 We found a discrepancy with the liquid drop fusion model: the fusion was faster for spheroids from e

176 surprisingly we found that the mitochondrial fusion mutants eat-3 and fzo-1 are more resistant to bot

177 both mitochondrial fission and mitochondrial fusion mutants showed increased sensitivity to osmotic s

178 Thus, beyond controlling myocyte fusion, Myog influences the MuSC:niche relationship, dem

179 leotide variants (n = 19), or FGFR1 or FGFR3 fusions (n = 9).

180 A proper 3D/4D image fusion needs to take into account the difference in the

181 in 70% of medullary thyroid cancers, and RET fusions occur rarely in other thyroid cancers.

182 ing segment switching process then occurs by fusion of actin fibers from the newly attached cells int

183 e actually allodiploid hybrids formed by the fusion of Aspergillus spinulosporus with an unknown clos

184 Existing approaches describe the fusion of cell aggregates by analogy with the coalescenc

185 r that can mimic both SA and FA via seamless fusion of complementary while compatible potentiometric

186 ll organization, such as extensive postnatal fusion of cranial bones in crown birds, can explain this

187 is an atlastin GTPase involved in homotypic fusion of endoplasmic reticulum (ER) tubules in the form

188 Live imaging revealed that Dstyk regulates fusion of membranes with the vacuole.

189 bserved in concert with increased number and fusion of mitochondria and production of reactive oxygen

190 An N-Lip C-Lip fusion of mouse lipin-2 is catalytically active, which s

191 of new, integrated structural databases and fusion of prediction tools toward protein disorder chara

192 PLSR models that developed based on data fusion of Raman and FT-IR spectral features obtained the

193 We identify that a fusion of the catalytic domain of TET1 to dCas9 targeted

194 complete loss of the cerebellar vermis with fusion of the cerebellar hemispheres, in 8/10 individual

195 to trigger rapid (<100 msec) and synchronous fusion of the docked vesicles.

196 GTPase of the dynamin superfamily, mediates fusion of the mitochondrial inner membranes, regulates c

197 y of a cell bridge variant consisting of the fusion of the mouse NG and SCG.

198 Coloboma originates from defective fusion of the optic fissure (OF), a transient gap that f

199 into sub-problems of low complexity and the fusion of the sub-problem solutions to form the solution

200 glycoprotein (Env) trimer that result in the fusion of the viral and cell membranes.

201 CE2 cell-surface receptors(1-4), followed by fusion of the virus and cell membranes to release the vi

202 y endocytosis(1), it is the HA that mediates fusion of the virus envelope with the membrane of the en

203 Pol2 is a fusion of two B-family Pols; the N-terminal Pol module i

204 s complete structural rearrangement to drive fusion of viral and cellular membranes(2,7,8).

205 nteraction translates to GP2 domain-mediated fusion of viral and endosomal membranes is not known.

206 IOPNs evaluated were found to have recurring fusions of ATP1B1-PRKACB (n = 13), DNAJB1-PRKACA (n = 6)

207 Nucleoporin 98 (NUP98) fusion oncoproteins are observed in a spectrum of hemato

208 It is characterized by fusion oncoproteins involving EWSR1 and variable members

209 Cancer-specific fusion oncoproteins, which display unique chromatin loca

210 formats, proteolysis or deconjugation at the fusion or conjugation site present further issues.

211 to one of three cohorts: patients with FGFR2 fusions or rearrangements, patients with other FGF/FGFR

212 ts Protocadherin 15a (Pcdh15a), Lipoma HMGIC fusion partner-like 5 (Lhfpl5), and Transmembrane inner

213 ional patterns and outcomes depending on the fusion partner.

214 hanism controlling Gc membrane insertion for fusion, pave the way for immunogen design to protect aga

215 rticularly the mutational sensitivity of the fusion peptide N terminus and the length sensitivity of

216 of which is required for the release of the fusion peptide(11,12).

217 re of this process is "zippering," whereby a fusion point moves directionally along an organ rudiment

218 these compartments are connected by membrane-fusion points, through which mature virions are transpor

219 ives rise to an unequal distance between the fusion pore and the electrode as well as fusion pore siz

220 sms such as incomplete cytokinesis or muscle fusion pore regulators.

221 the fusion pore and the electrode as well as fusion pore size, which leads to different average spike

222 inst organoids derived from the FGFR1-ERLIN2 fusion-positive ASCP PDX model.

223 fusions (six [86%] of 7 patients) and PDGFRB fusion-positive B-cell acute lymphocytic leukaemia (43 [

224 014, and Feb 19, 2019, 159 patients with TRK fusion-positive cancer were enrolled and treated with la

225 d therapies, such as TRK inhibitors for NTRK fusion-positive cancers.

226 Up to 36% of patients with ROS1 fusion-positive NSCLC have brain metastases at the diagn

227 ight (seven [10%] of 68 patients in the NTRK fusion-positive safety population and in 18 [5%] of 355

228 have anti-tumour activity against NTRK gene fusion-positive solid tumours, including CNS activity du

229 ired for optimal bone healing and osteoclast fusion, potentially via its regulation of Pmepa1 express

230 peutic targets, yet low consensus of RNA-Seq fusion prediction algorithms makes therapeutic prioritiz

231 of ROS1, the diagnostic challenges that ROS1 fusions present and the strategies to target ROS1 fusion

232 alize intermediates of the HIV-cell membrane fusion process and demonstrate how Serinc proteins preve

233 icons incorporating nonfunctional 3Bs and 3B fusion products in competition and complementation assay

234 We hypothesize that the fusion protein acts through a dominant-negative mechanis

235 Expression of the fluorescent fusion protein allows quantitative analyses of cytotoxic

236 Nimonkar et al. now present a fusion protein between LPL and its physiological transpo

237 ors of the respiratory syncytial virus (RSV) fusion protein block entry of the virus into the cell an

238 nti-LDLRAD3 antibodies and an LDLRAD3(D1)-Fc fusion protein block VEEV infection in cell culture.

239 Here, we show that expression of a fusion protein combining wheat GROWTH-REGULATING FACTOR

240 E3 protein-ubiquitin ligase; and GCalpha, a fusion protein composed of a guanylyl cyclase and a phos

241 FLT3, our team engineered an alpha-FLT3-A192 fusion protein composed of a single chain variable fragm

242 Here, a fusion protein containing an N-terminal cutinase and a C

243 generally considered that CBFbeta-SMMHC, the fusion protein encoded by CBFB-MYH11, is a dominant nega

244 ainfluenza virus (PIV) vector expressing RSV fusion protein engineered for enhanced immunogenicity.

245 Additionally, the LPL-GPIHBP1 fusion protein exhibited high enzyme activity in in vitr

246 e presented the fabrication of a recombinant fusion protein from recombinant human-like collagen (HLC

247 in the mitochondrial cristae biogenesis and fusion protein optic atrophy 1 (Opa1), retinal ganglion

248 We also show that the SA-IL-4 fusion protein prevents immune-cell infiltration in the

249 This bispecific fusion protein redirects T cells to specifically lyse in

250 The development of a decoy-receptor fusion protein suggests a strategy for the prevention of

251 al epithelial cell line expressing a LC3-GFP fusion protein was challenged with normalized secretomes

252 peptide derived from a prevalent CBFB-MYH11 fusion protein was found to be immunogenic in HLA-B*40:0

253 F, a class I fusion protein, contains the archetypal heptad repeat re

254 erated by trypsin cleavage of soluble HttEx1 fusion protein, which we analyze in some detail.

255 highly expressed and targets of the EWS-WT1 fusion protein.

256 lpC and clpE stabilized the GFP::SpxA2(tail) fusion protein.

257 l TMEM175 channel in complex with a nanobody fusion-protein disclosing bound K(+) ions.

258 from mice immunized with selected gp120-CD4i fusion proteins and found that their footprints on Env a

259 imize the nND immune response by engineering fusion proteins consisting of gp120 Core and one or two

260 aring effect for subsequent vaccination with fusion proteins containing the Ag 85B epitope and consis

261 These WPGD1 and WPGD2 fusion proteins import into isolated chloroplasts, demon

262 ns present and the strategies to target ROS1 fusion proteins in both treatment-naive and acquired-res

263 sation of glycosylation across class I viral fusion proteins influence not only individual glycan com

264 As expected, the fusion proteins possess improved antigenicity with retai

265 nal six cysteine domain (6C) with the use of fusion proteins to facilitate expression and folding.

266 ll1 (Kmt2a) gene generate powerful oncogenic fusion proteins, predominantly affecting infant and paed

267 ptional programs controlled by diverse NUP98-fusion proteins, we developed mouse models for regulatab

268 king nND epitopes, referred to as gp120-CD4i fusion proteins.

269 report a Pten derived pro-cancer growth gene fusion Pten-NOLC1 originated from a chr10 genome rearran

270 clei number in the fused macrophage, and the fusion rates were matrix dependent.

271 native chromosome in some isolates and this fusion restored wild-type growth.

272 tingale song and are structurally similar to fusion rhythms (ornaments) in music.

273 y achieved an alpha-heating regime, in which fusion self-heating is the dominant source of yield, by

274 release probability (e.g. by a facilitation fusion sensor) generate too little facilitation and too

275 Notably, 75 human genes formed fusion sequences due to viral insertional integration.

276 ts, and most prevalent in patients with ABL2 fusions (six [86%] of 7 patients) and PDGFRB fusion-posi

277 al-trap optical tweezers setup, we found the fusion speeds of four types of droplets to differ by two

278 his footprint are key to stabilizing the pre-fusion spike.

279 the membranes and the formation of transient fusion stalks in molecular dynamics simulations and a co

280 a second type of membrane fusion, cell-cell fusion (syncytium formation), which is linked to pathoge

281 ubiquitin-activated interaction trap (UBAIT) fusion system can efficiently isolate the complex intera

282 A focused review of gene fusions, their pathogenic mechanism, and gene fusion det

283 r in combination, on receptor binding, pH of fusion, thermal stability, and virus replication were in

284 correlations between low modulation flicker fusion threshold and reading rate for the two subgroups

285 the cGAS-STING pathway senses unnatural cell fusion through micronuclei formation as a danger signal,

286 zed and controlled, and reconstituting viral fusion to synthetic membranes, which introduces nonphysi

287 n synaptotagmin-1 and the SNAREs in membrane fusion to trigger release.

288 Fusion transcripts can contribute to diversity of molecu

289 The fusion transcripts in fetal brain were enriched for gene

290 uring oncogenic NTRK1, NTRK2, and NTRK3 gene fusions treated in three ongoing, early-phase trials.

291 elope protein (Env) mediates viral-host cell fusion via a network of conformational transitions, with

292 ment significantly co-relaxed when binocular fusion was attained from monocular target fixation (P <

293 pancy with the liquid drop fusion model: the fusion was faster for spheroids from epithelial cells wi

294 Here, to further study the process of fusion, we incubate HA for different times at pH 5.0 and

295 The most common fusions were KIF5B-RET in females [80% (12/15)] and CCDC

296 The identified fusions were largely private and 4 specific recurring ev

297 of RET tyrosine kinase leading to a TFG-RET fusion which transforms immortalized human thyroid cells

298 Delta chromosome was found to have undergone fusion with another native chromosome in some isolates a

299 our approach models interdomain information fusion with bipartite graph convolution operation.

300 We have reconstituted fusion with pure components from yeast vacuoles includin

301 ine-kinase promoter but could be restored by fusion with the 100 bp minimum transcription initiation