ライフサイエンスコーパス: fusion protein

1 ein and as a capsid protein-delta (CP-delta) fusion protein.

2 phosphorylation event in and binding to the fusion protein.

3 arry-over of E. coli DNA introduced with the fusion protein.

4 and subsequent degradation of the oncogenic fusion protein.

5 ich then tethers a protein A-Tn5 transposase fusion protein.

6 -1 receptor accessory protein, into a single fusion protein.

7 essing a previously published TRPV4-ferritin fusion protein.

8 erization of cryptochrome 2 and a dCas9-CIBN fusion protein.

9 highly expressed and targets of the EWS-WT1 fusion protein.

10 rm using a fourth-generation HCV recombinant fusion protein.

11 ope-specific responses compared to the viral fusion protein.

12 interactions and globally destabilizing the fusion protein.

13 lpC and clpE stabilized the GFP::SpxA2(tail) fusion protein.

14 E2A gene and produces an oncogenic E2A-PBX1 fusion protein.

15 anes and would be perturbed in the oncogenic fusion protein.

16 ectopic expression of an LT-resistant MKK7-4 fusion protein.

17 nd in wild-type mice injected with IL-21R-Fc fusion-protein.

18 of constitutive activator and repressor HY5 fusion proteins.

19 he rational design of linkers in therapeutic fusion proteins.

20 nonenveloped viruses do not encode membrane fusion proteins.

21 king nND epitopes, referred to as gp120-CD4i fusion proteins.

22 is consistent with metastability of class I fusion proteins.

23 nt of the conformational transition of viral fusion proteins.

24 on and resistance to degradation of the YAP1 fusion proteins.

25 t of direct transcriptional targets of NUP98-fusion proteins.

26 viously examined fluorescent DNA replication fusion proteins.

27 ombination treatment with TCB antibody-based fusion proteins.

28 lockade using the CTLA-4-immunoglobulin (Ig) fusion protein (abatacept) in a mouse model of diabetes

29 We hypothesize that the fusion protein acts through a dominant-negative mechanis

30 proliferation experiments, proving that the fusion protein (administered as a DNA vaccine) maintaine

31 Expression of the fluorescent fusion protein allows quantitative analyses of cytotoxic

32 Having cross-reactive epitopes, the fusion protein also induces potent antibody responses ag

33 The oncogenic fusion protein AML1-ETO retains the ability of AML1 to i

34 to interleukin-22 immunoglobulin Fc (IL22Fc) fusion protein and anti-p40 monoclonal antibody treatmen

35 stitutively synthesized the YopE(Nt138)-LcrV fusion protein and secreted it via the type 3 secretion

36 protein can bind to a BCMA-like receptor Ig fusion protein and to both BCMAL1- and BCMAL2-transfecte

37 We immunized C57BL/6 mice with these fusion proteins and found that overall the fusion protei

38 from mice immunized with selected gp120-CD4i fusion proteins and found that their footprints on Env a

39 Concomitant decrease in mitochondrial fusion proteins and increased fission proteins in these

40 l changes that trigger refolding of trimeric fusion proteins and membrane fusion.

41 Localization of fluorescent fusion proteins and mutant studies were carried out to c

42 uent subcellular localization of fluorescent fusion proteins and n-glycan profiling revealed that a c

43 scovered multifunctionality of mitochondrial fusion proteins and newly defined mechanisms for direct

44 notherapies including monoclonal antibodies, fusion proteins and peptidomimetics that have been appro

45 EGFR ligands, produced as FimH fusion proteins and released by proteolytic cleavage, bo

46 t assembles between cells includes the viral fusion proteins and various accessory proteins that prev

47 AST proteins are the smallest viral membrane fusion proteins and, unlike their enveloped virus counte

48 For many viruses, the clustering of fusion proteins-and their distribution on virus particle

49 as small molecules, biotherapeutics such as fusion proteins, antibody-drug conjugates, or bispecific

50 RUNX1 and the AML1-ETO fusion protein are coexpressed in t(8;21) AML cells and

51 ments leading to the generation of oncogenic fusion proteins are a common feature of many cancers.

52 wn players such as certain lipid species and fusion proteins are generally believed to alter the free

53 3-defective kernel phenotype, indicating the fusion proteins are targeted to the amyloplast.

54 In many cases, these fusion proteins are thought to be the primary driver of

55 Fluorescent EV fusion proteins are useful for the study of EV biogenesi

56 Our data strongly supports the use of this fusion protein as a component of an anti-virulence based

57 uction of proinsulin-transferrin (ProINS-Tf) fusion protein as a liver-specific protein prodrug to ac

58 CE-083 - a locally acting, follistatin-based fusion protein - as a novel therapeutic agent for focal

59 ave implications for the function of class I fusion proteins, as well as antibody prophylaxis and vac

60 These fusion proteins assemble into multi-valent nanoparticles

61 If a fusion protein assembles into a non-covalent oligomeric

62 oteins AtEDE1 and AtMAP65-4, and the vesicle fusion protein AtKNOLLE by recognizing their genomic ele

63 Nimonkar et al. now present a fusion protein between LPL and its physiological transpo

64 The natural Cas8-Cas5 fusion protein binds the 5' crRNA handle and contacts th

65 ors of the respiratory syncytial virus (RSV) fusion protein block entry of the virus into the cell an

66 nti-LDLRAD3 antibodies and an LDLRAD3(D1)-Fc fusion protein block VEEV infection in cell culture.

67 -Ig (cytotoxic T-lymphocyte antigen 4-Ig), a fusion protein blocking costimulatory signaling between

68 tomized phage display selections against the fusion protein BRIL, an engineered variant of apocytochr

69 (Physcomitrium [Physcomitrella] patens) ROP4 fusion protein by inserting mNeonGreen after Gly-134.

70 The assay utilizes a recombinant fusion protein, called Topanga reagent, generated by joi

71 Interestingly, we also found that NUP214 fusion proteins, causative for certain cases of T-cell a

72 ter-soluble and membrane proteins to achieve fusion protein cleavage under biocompatible conditions w

73 We generated Cetuximab-based IL-10 fusion protein (CmAb-(IL10)(2)) to prolong its half-life

74 toward activated platelets via a recombinant fusion protein combining a single-chain antibody against

75 One isoform of VLT-ORF63, encoding a fusion protein combining VLT and ORF63 proteins, induces

76 Here, we show that expression of a fusion protein combining wheat GROWTH-REGULATING FACTOR

77 Moreover, AtCGL20A-eGFP fusion proteins comigrated with 50S ribosomal subunits i

78 E3 protein-ubiquitin ligase; and GCalpha, a fusion protein composed of a guanylyl cyclase and a phos

79 FLT3, our team engineered an alpha-FLT3-A192 fusion protein composed of a single chain variable fragm

80 PE-PilA is a fusion protein composed of immunologically relevant part

81 The biosensor is based on a bi-functional fusion protein, composed by the lambdaN peptide that rec

82 ed by a 3.0- angstrom crystal structure of a fusion protein comprising Nef and the cytoplasmic domain

83 Fusion, mediated by the membrane fusion protein Comt/NSF and ESCRT-III components Shrub/C

84 tudy suggest that LpqN may act as a membrane fusion protein, connecting MmpL transporters with peripl

85 Here, we introduce a new fusion protein consisting of a light-activated adenylyl

86 BIVV001 was bioengineered as a unique fusion protein consisting of a VWF-D'D3 domain fused to

87 oach that maximizes translation to humans, a fusion protein consisting of immunogenic portions of PdS

88 imize the nND immune response by engineering fusion proteins consisting of gp120 Core and one or two

89 d DNA methylation levels than a dCas9-DNMT3a fusion protein construct at C9orf72, and genome-wide met

90 Flavocytochrome P450 BM3 is a natural fusion protein constructed of cytochrome P450 and NADPH-

91 Here, a fusion protein containing an N-terminal cutinase and a C

92 On the contrary, fusion proteins containing only the TMD of JPH1 were abl

93 aring effect for subsequent vaccination with fusion proteins containing the Ag 85B epitope and consis

94 sent irreversible inhibitors for enzymes and fusion proteins containing the enzyme domains.

95 F, a class I fusion protein, contains the archetypal heptad repeat re

96 trongly suggests that this novel recombinant fusion protein could be more beneficial in the treatment

97 were not inserted; however, an MBP-2Pf3-Lep fusion protein could be ranslocated.

98 model that suboptimal immunizations with RSV fusion protein could induce lung disease enhancement.

99 iers, membrane homeostasis proteins, fission-fusion proteins, cristae-shape controlling and MICOS pro

100 Furthermore, the fusion protein degraded and released hBMP-2 in vivo allo

101 We reasoned that different NUP98-fusion proteins deregulate a common set of transcription

102 Bifunctional fusion protein design has been widely utilized as a stra

103 osed a novel application of the bifunctional fusion protein design through the introduction of proins

104 BIVV001 (rFVIIIFc-VWF-XTEN) is a novel fusion protein designed to overcome this half-life ceili

105 l TMEM175 channel in complex with a nanobody fusion-protein disclosing bound K(+) ions.

106 We found that whereas a MyoVa-Rab27a fusion protein dispersed melanosomes in MyoVa-deficient

107 Upon expression of this fusion protein, DNA in proximity to the POI is methylate

108 Injecting this fusion protein effectively lowers plasma triglycerides i

109 thermore, bacterially produced nanobody-RING fusion proteins electroporated into cells induce degrada

110 e fusion proteins and found that overall the fusion proteins elicit more focused CD4bs Ab response th

111 The high stability of the fusion protein enabled us to identify LPL amino acids th

112 generally considered that CBFbeta-SMMHC, the fusion protein encoded by CBFB-MYH11, is a dominant nega

113 Influenza A virus PA-X is a fusion protein encoded in part by a +1 frameshifted open

114 ainfluenza virus (PIV) vector expressing RSV fusion protein engineered for enhanced immunogenicity.

115 ne containing 30 ug, 60 ug, or 120 ug of RSV fusion protein engineered to preferentially maintain a p

116 nfusion of recombinant therapeutics, ApoM-Fc fusion protein enhanced kidney and lung regeneration and

117 utations, we can show that all of these YAP1 fusion proteins exert TEAD-dependent YAP activity, while

118 Additionally, the LPL-GPIHBP1 fusion protein exhibited high enzyme activity in in vitr

119 HaloTag-GFP fusion proteins expressed on mitochondria were successfu

120 The mumps virus (MuV) fusion protein (F) plays a crucial role for the entry pr

121 ants might correlate with the ability of the fusion protein (F) to mediate cell-to-cell fusion.

122 utilizes the attachment protein (G) and the fusion protein (F) to perform these critical functions.

123 on show promise, vaccines aimed at eliciting fusion protein (F)-targeting antibodies have repeatedly

124 a single amino acid alteration in the viral fusion protein (F; L454W) was previously identified in t

125 Moreover, the recombinant fusion protein fabricated a vertical through-hole struct

126 ically looked for previously uncharacterized fusion proteins featuring a PUA or DUF3427 domain and HN

127 fibroblast growth factor receptor 2 (FGFR2) fusion proteins (FFs) generated by chromosomal transloca

128 The functional ROP fusion protein formed a steep gradient at the apical pla

129 he IGPS-phosphoribosylanthranilate isomerase fusion protein from Escherichia coli Here, we present th

130 e presented the fabrication of a recombinant fusion protein from recombinant human-like collagen (HLC

131 anslocation of a photoconverted PAR(2)-Kaede fusion protein from the Golgi to the plasma membrane of

132 ites are also present in other mitochondrial fusion proteins from fungi, plants, and animals.

133 Review, we discuss how our understanding of fusion protein function is informing therapeutic innovat

134 The resulting fusion proteins, FUS-CHOP and EWS-FLI, drive aberrant tr

135 The viral fusion protein gB is nonfusogenic on its own and require

136 ivation of gH/gL, which in turn triggers the fusion protein gB to undergo rearrangements leading to m

137 L130-UL131A pentamer), as well gH-gL and the fusion protein gB, which are conserved in all herpesviru

138 HIV-1 entry into cells is mediated by the fusion protein gp41.

139 es large-scale conformational changes of the fusion protein gp41.

140 Inducible fluorescent histone 2B fusion protein (H2B-FP) transgenic mice are important to

141 DUF3427 domain containing fusion proteins had very little or no endonuclease activ

142 These results indicate that the LPL-GPIHBP1 fusion protein has potential for use as a therapeutic fo

143 lar functions of a number of these oncogenic fusion proteins have been discovered.

144 that mice immunized with selected gp120-CD4i fusion proteins have higher frequencies of germinal cent

145 ion forms of RSV F, as well as other class I fusion proteins, have revealed compact trimeric arrangem

146 tinct cellular compartments, with the former fusion protein having particularly low off-target activi

147 w specific, irreversible labeling of HaloTag fusion proteins; however, measurement of protein of inte

148 esis machineries, instances of the RmlC-RmlD fusion protein identified here exist across the Haptophy

149 We engineered immunomodulatory fusion proteins (IFPs) to enhance ACT efficacy, combinin

150 These WPGD1 and WPGD2 fusion proteins import into isolated chloroplasts, demon

151 lA can thus be further developed as a single fusion protein in a vaccine perspective, in the knowledg

152 nd the understanding of the function of this fusion protein in cancer cells, we expressed in E. coli,

153 ns present and the strategies to target ROS1 fusion proteins in both treatment-naive and acquired-res

154 ework of a molecular mechanism for oncogenic fusion proteins in cancers.

155 Here we examine the activities of SSB-IDL fusion proteins in which fluorescent domains are inserte

156 To this end, we generated fusion proteins in which the catalytic domains of differ

157 eins with transcriptome profiling upon acute fusion protein inactivation in vivo, we defined the core

158 ion inhibition by GA of all three classes of fusion proteins including HIV, Ebola virus (EBOV), influ

159 ontrast to requirements of related class III fusion proteins, including vesicular stomatitis virus gl

160 e nonhomologous parainfluenza virus 5 (PIV5) fusion protein, indicating a requirement for specific in

161 verexpression of ectopic RNF168 or a ub-H2AX fusion protein induced cell death and delayed BRCA1-muta

162 sation of glycosylation across class I viral fusion proteins influence not only individual glycan com

163 FPPa-OmoMYC-treated cells indicated that the fusion protein inhibited MYC-dependent networks, inducin

164 oxins, which specifically proteolyze vesicle fusion proteins involved in regulated secretion, have be

165 he toxicity and phase separation of aberrant fusion proteins involved in sarcoma.

166 Fusion proteins involving Nucleoporin 98 (NUP98) are rec

167 The NPM-ALK fusion protein is a constitutively-active tyrosine kinas

168 y cells, and that a synthetic ADAM10/Tspan15 fusion protein is a functional scissor.

169 We estimated that NPM-ALK fusion protein is expressed at substantial levels in bot

170 microspore-specific activity and a MYB81-RFP fusion protein is only expressed in a narrow window prio

171 The enzyme activity of the HIRMAb-enzyme fusion protein is preserved for hexosaminidase A, which

172 mal external region (MPER) of the HIV-1 gp41 fusion protein is targeted by the most broadly reactive

173 unogenicity, solubility, and stability of Fc fusion proteins, it should be thoroughly characterized.

174 protein kinase (PKA), replacing exon 1, this fusion protein, J-C subunit (J-C), becomes the driver of

175 mically administered serum albumin (SA)-IL-4 fusion protein leads to higher efficacy in preventing di

176 e endogenous MeCP2 and recombinant TAT-MeCP2 fusion protein levels in a 96-well plate format.

177 tein, the same drug library was screened and fusion protein levels were directly measured as a read-o

178 t caution should be taken in interpreting FP-fusion protein localization data when amyloid structures

179 A functional MtNPD1:GFP fusion protein localized in the space surrounding symbio

180 Confocal micrographs of EGFP fusion proteins localized at key cell organelles in muri

181 A 35S:VEN4-eGFP fusion protein localizes to the nucleus in Arabidopsis (

182 nous and subcutaneous administrations of the fusion protein lowered triglycerides in several mouse st

183 re transduced with a novel optochemogenetics fusion protein, luminopsin 3 (LMO3), which consisted of

184 The SA-IL-4 fusion protein may be prophylactically and therapeutical

185 vities of the two constituent enzymes in the fusion protein may have evolved to ensure a robust but t

186 We have cloned a malarial antigen-containing fusion protein, MBP-pfMSP1(19), in Escherichia coli, whi

187 V is the fusion (F) protein, a class I viral fusion protein mediating virus-cell membrane fusion.

188 ssion phenotype through the knockdown of the fusion protein mitofusin (MFN)-2 strongly reduced the mi

189 oogenesis, triggered by reduction of the pro-fusion protein Mitofusin.

190 report that the absence of the mitochondrial fusion proteins mitofusin1 (MFN1) and mitofusin2 (MFN2)

191 duction via selective control of fission and fusion proteins (mitofusins, OPA1 and DRP1) as well as t

192 A fusion protein, named dm6ACRISPR, was created by linking

193 at the Ta7ANPR1 locus through an NB-ARC-NPR1 fusion protein negatively regulating the defence to stem

194 Rilonacept, a soluble IL-1 receptor chimeric fusion protein neutralizing IL-1alpha and IL-1beta, has

195 hown that a membrane-tethered Neurotactin-Wg fusion protein (NRT-Wg) can largely replace endogenous W

196 a new knock-in mouse line, which expresses a fusion protein of granzyme B, a key component of cytotox

197 dentify proteins within close proximity to a fusion protein of interest.

198 troviral expression of an estrogen-dependent fusion protein of the HoxB8 transcription factor.

199 biotin-ligase BirA* to the AIS by generating fusion proteins of BirA* with NF186, Ndel1, and Trim46;

200 tic and genetic dimers of mEos3.2 as well as fusion proteins of monomeric and dimeric membrane protei

201 yridinium(+) (MPP(+)) by cell-free-expressed fusion proteins of rOCT1 and rOCT1 mutants with green fl

202 and epiregulin (EPRG) were expressed as FimH fusion proteins on the surface of E. coli bacteria.

203 oteolytic inactivation of the inner membrane fusion protein OPA1.

204 in the mitochondrial cristae biogenesis and fusion protein optic atrophy 1 (Opa1), retinal ganglion

205 pression of the mitochondrial inner membrane fusion protein optic atrophy type 1, and components of t

206 to other malignancies that harbor oncogenic fusion proteins or other characteristic genetic markers.

207 no associated viral vector encoding RSPO1-Fc fusion protein, or control vector, was injected into Apc

208 ive expression system, without the need of a fusion protein partner, for the Pfs48/45 6C protein frag

209 sive for the binding of the tumor driver and fusion protein PAX3-FOXO1, allowing downstream transcrip

210 characterized by expression of the oncogenic fusion protein PAX3-FOXO1, which is critical for tumorig

211 inia Ankara-SIV (MVA-SIV), and HIV-gp120-CD4 fusion protein plus adjuvants, which consistently reduce

212 emia (APL) is characterized by the oncogenic fusion protein PML-RARalpha, a major etiological agent i

213 As expected, the fusion proteins possess improved antigenicity with retai

214 Serum antibodies against the prefusion RSV fusion protein (pre-F) exhibit high neutralizing activit

215 ll1 (Kmt2a) gene generate powerful oncogenic fusion proteins, predominantly affecting infant and paed

216 The fusion protein preserved the characteristic of HLC allow

217 We also show that the SA-IL-4 fusion protein prevents immune-cell infiltration in the

218 a conserved, critical direct target of NUP98-fusion proteins, proposing CDK4/CDK6 inhibitors as a new

219 rAd5 constructs expressing CD40-targeted S1 fusion protein (rAd5-S1/F/CD40L), untargeted S1 (rAd5-S1

220 This bispecific fusion protein redirects T cells to specifically lyse in

221 Accordingly, a Mlph-Rab27a fusion protein reduced MyoVa smFRAP, indicating that it

222 and the mitochondria of Arabidopsis with the fusion protein roGFP2-Orp1 using confocal microscopy and

223 eloid leukemia (AML) patients that carry the fusion protein RUNX1-RUNX1T1 produced by t (8;21) (q22;q

224 utative transmembrane domains, and PIC30-GFP fusion protein selectively localizes to the plasma membr

225 Cas9 nucleases, and the resulting Cas9-DN1S fusion proteins significantly block NHEJ events specific

226 l approaches including binding analysis with fusion proteins, siRNA-mediated gene silencing, RT-PCR,

227 a protein A-Micrococcal Nuclease (pA/MNase) fusion protein (Skene and Henikoff, 2017).

228 M-TM interactions significantly impact viral fusion protein stability and function, presenting these

229 ns out that the GFP tagging location and the fusion protein stability have a large effect on LacI bin

230 vity of activin receptor ligand traps, novel fusion proteins such as luspatercept that are promising

231 the isolated transmembrane domains (TMDs) of fusion proteins such as SNARE molecules drastically lowe

232 The development of a decoy-receptor fusion protein suggests a strategy for the prevention of

233 fferent Escherichia coli competent cells and fusion protein tags for the recombinant production of hu

234 We report a single fusion protein (TBA(225)) consisting of the toxoid versi

235 The examples indicate that the FimH-fusion protein technology can be used in various applica

236 e we describe the engineering of an antibody fusion protein, termed F8-4-1BBL, that does not exhibit

237 re immunogenic as a subentity of the PE-PilA fusion protein than when it was injected as an isolated

238 Luspatercept, a recombinant fusion protein that binds to select transforming growth

239 Abatacept is a CTLA-4-Ig fusion protein that binds to the costimulatory ligands C

240 Luspatercept, a recombinant fusion protein that binds transforming growth factor bet

241 dentification of mutations in the viral gp41 fusion protein that counteracted cholesterol depletion.

242 DAB-IL-2, Ontak) is a diphtheria-toxin-based fusion protein that depletes CD25-positive cells includi

243 domain of CheA and a variant CheW-CheR-like fusion protein that is critical for maintaining an order

244 Despite bearing a fusion protein that is less stable at 37 degrees C than

245 A RAB-3::GFP fusion protein that is normally localized to presynaptic

246 functions of this interface in yeast using a fusion protein that joins Smc3p to Mcd1p.

247 tial virus (RSV) F glycoprotein is a class I fusion protein that mediates viral entry and is a major

248 a (Poltheta) is a unique polymerase-helicase fusion protein that promotes microhomology-mediated end-

249 eric antigen receptors (CARs) are artificial fusion proteins that cause CD19-specific T-cell activati

250 Herein, we describe a new series of fusion proteins that have been developed to self-assembl

251 te T cells, and they also create soluble TCR fusion proteins that specifically recognize cognate pept

252 covery and activities of several key sets of fusion proteins that together offer an evolving perspect

253 As with other class-I membrane-fusion proteins, the spike protein is post-translational

254 nt in performance was demonstrated for an Fc-fusion protein therapeutic.

255 ApoB-fusion proteins thus represent a sensitive and specific

256 Viral fusion protein TM-TM interactions are important for prot

257 li, purified and characterized human NPM-ALK fusion protein to be used as a standard for estimating e

258 ro studies of RRV vCD200 have utilized an Fc fusion protein to examine functionality, which does not

259 Here, we constructed a GFP-NAMPT fusion protein to study NAMPT's subcellular trafficking.

260 eting of the heterologous channelrhodopsin-2 fusion protein to the inner mitochondrial membrane and f

261 he binding characteristics of this activated fusion protein to the insulin receptor to elucidate its

262 The capability of these fusion proteins to complement the function of the native

263 e stably expressing alpha-syn (A53T)-CFP/YFP fusion proteins to detect alpha-syn seeds in brain extra

264 nal six cysteine domain (6C) with the use of fusion proteins to facilitate expression and folding.

265 mployed a panel of N-cadherin-alphaE-catenin fusion proteins to rebuild AJs with specific actin linka

266 em is the use of stable and native TAT-MeCP2 fusion proteins to replenish its levels in neurons after

267 To test this, we used fusion proteins to track synaptic vesicle localization a

268 The viral fusion protein triggers from the pre- to the postfusion

269 receptor-enhanced green fluorescent protein fusion protein under the control of the promoter/enhance

270 The design of fusion protein vaccines with the ability to recruit BCG-

271 al epithelial cell line expressing a LC3-GFP fusion protein was challenged with normalized secretomes

272 for surface modification, CD200-streptavidin fusion protein was expressed from bacteria transformed w

273 peptide derived from a prevalent CBFB-MYH11 fusion protein was found to be immunogenic in HLA-B*40:0

274 Cupid-Green Fluorescent Protein (Cupid-GFP) fusion protein was tested on mammalian, whole plant cell

275 rcadian reporter mice expressing a PER2::LUC fusion protein, we isolated dorsal root ganglia (DRG), t

276 reporter gene and a gene encoding TREM2DAP12 fusion protein, we show here that TREM2-dependent signal

277 ptional programs controlled by diverse NUP98-fusion proteins, we developed mouse models for regulatab

278 Using fluorescent fusion proteins, we experimentally demonstrated that bot

279 tation of conventional antibody-superantigen fusion proteins, we have split a superantigen into two f

280 ntaining endonucleases, the ORFs for DUF3427 fusion proteins were frequently found in defense islands

281 The fusion proteins were functionally active and could be re

282 r characterization of EVs confirmed that the fusion proteins were loaded onto exosomes without alteri

283 All GFP-ERF fusion proteins were nuclear-localised.

284 This fusion protein when applied to cranial defects in rats w

285 ocal microscopy analysis indicates that most fusion proteins when incubated with cells at 10 uM local

286 e-engineered for BBB transport as IgG-enzyme fusion proteins, where the IgG domain is a monoclonal an

287 ts SIV Tat binding to TAR, but not a Tat-Rev fusion protein, which activates transcription when Rev b

288 tes the AML1-eight-twenty-one (ETO) leukemia fusion protein, which contains the DNA-binding domain of

289 erated by trypsin cleavage of soluble HttEx1 fusion protein, which we analyze in some detail.

290 represents a prototype for antibody-cytokine fusion proteins, which conditionally display "activity o

291 Etanercept is a recombinant Fc fusion protein widely used to treat rheumatic diseases.

292 s a second-generation diphtheria-toxin-based fusion protein with promise as a cancer immunotherapeuti

293 0G-ChABC) was achieved by expressing it as a fusion protein with Src homology 3 (SH3) and delivering

294 ion by blocking the interaction of the viral fusion protein with the cell membrane.

295 Thus, using gp120-CD4i fusion proteins with selective glycan deletion as immuno

296 rating chromatin occupancy profiles of NUP98-fusion proteins with transcriptome profiling upon acute

297 pressing macroH2A isoforms (mH2A1 and mH2A2) fusion proteins (with GFP) under identified endogenous p

298 oped a new IL-2-based biologic, an IL-2/CD25 fusion protein, with greatly improved pharmacokinetics a

299 complex and its derivative, the LPL-GPIHBP1 fusion protein, with the goal of contributing to the dev

300 le mutations was used to deliver a Y. pestis fusion protein, YopE amino acid 1 to 138-LcrV (YopE(Nt13