ライフサイエンスコーパス: fusogenic

1 anges that are required for making the virus fusogenic.

2 infectious particles and was constitutively fusogenic.

3 hich constitute a related genus and are also fusogenic.

4 ranscriptionally active in the placenta, and fusogenic.

5 r mutant SER viruses, which were found to be fusogenic.

6 e-forming compositions are frequently highly fusogenic.

7 therefore preventing the virus from becoming fusogenic.

8 ains of its fusion protein, RSV-F, to form a fusogenic 6-helix bundle that enables the virus to penet

9 We find that to be fusogenic a SNARE topology must support both basal fusio

10 n protein and could enable the infection and fusogenic abilities of a gp64-null prototype baculovirus

11 p41 is highly conserved and critical for the fusogenic ability of the virus.

12 ind to trans-SNARE complexes to direct their fusogenic action.

13 We evaluated the fusogenic activities of MV and VSV-FH in relationship to

14 finding that chemically inert PFCs exhibited fusogenic activity and marked changes in membrane surfac

15 that TMD dissociation is required for HeV F fusogenic activity and strengthens our model for HeV fus

16 We propose a model in which a unique fusogenic activity at the C terminus of VgrG5 facilitate

17 responsible for the reported differences in fusogenic activity between these peptides.

18 oth the bovine and ovine orthologs displayed fusogenic activity by conferring infectivity on retrovir

19 codes a membrane-bound envelope protein with fusogenic activity ex vivo, is expressed at the placenta

20 ting and fusogenicity are separable and that fusogenic activity has been uncoupled from other protein

21 This envelope protein does not disclose any fusogenic activity in ex vivo assays, at variance with t

22 lly, gB palmitoylation was required for full fusogenic activity in human epithelial cells.

23 In addition, its fusogenic activity is significantly more resistant to re

24 Fusogenic activity of full-length protein expressed in M

25 cofusogen with gB but instead regulates the fusogenic activity of gB.

26 n immunodeficiency virus type I requires the fusogenic activity of gp41, the transmembrane subunit of

27 operate with myomaker and substitute for the fusogenic activity of mammalian myomixer.

28 of GTPase domain dimerization abolishes the fusogenic activity of MFN1.

29 The fusogenic activity of Minion is conserved in the human o

30 th annexin-binding protein S100A4, regulated fusogenic activity of syncytin 1.

31 nt on both CCR5 expression levels as well as fusogenic activity of the Env glycoprotein.

32 PL binds to ASGPR on the hepatocyte surface, fusogenic activity of the F-protein delivers the DNA int

33 servations to characterize the unprecedented fusogenic activity of the MPER-TMD junction.

34 rates occurs by myoblast fusion and requires fusogenic activity of the muscle-specific membrane prote

35 e 221, but the gp41 changes did increase the fusogenic activity of the SIV envelope two- to threefold

36 CO2 sensitivity is caused by the fusogenic activity of the viral glycoprotein, which resu

37 in the transduced cells and depended on the fusogenic activity of this protein, substantiating the h

38 ghts into the role of the MPER in regulating fusogenic activity of viral glycoproteins.

39 lmitoylation was not sufficient for complete fusogenic activity suggesting a function for other amino

40 can both proceed normally in the absence of fusogenic activity suggests that properly assembled and

41 Thus, the CMV gH/gL complex has inherent fusogenic activity that can be measured in certain cell

42 EFF-1 can confer potent fusogenic activity to nonfusing cell types.

43 Thus, myomaker and myomerger together confer fusogenic activity to otherwise non-fusogenic cells.

44 cium ions (Ca(2+)) play an important role in fusogenic activity via a Ca(2+) binding pocket with cons

45 man or murine uPAR were engineered and their fusogenic activity was determined.

46 , Ala) residues resulted in complete loss of fusogenic activity with the N terminus and markedly redu

47 Here we conferred fusogenic activity without transdifferentiation to multi

48 the VgrG5 C-terminal domain is required for fusogenic activity, and we identify sequence motifs, inc

49 e retention of a significant fraction of the fusogenic activity, as long as the mutant proteins inter

50 ities may have unequal weights in triggering fusogenic activity, depending on the ratios of gB and gD

51 Its cognate receptor, required for its fusogenic activity, was searched for by a screening assa

52 alian hosts by altering virion stability and fusogenic activity.

53 for purifying selection and conservation of fusogenic activity.

54 for purifying selection and conservation of fusogenic activity.

55 ctivate HBMEC membrane rafts and induce cell fusogenic activity.

56 reen for antibodies that interfere with gB's fusogenic activity.

57 ah virus fusion protein (NiV-F) modulate its fusogenic activity.

58 F protein on protein folding, transport, and fusogenic activity.

59 ed to the cell surface but which had reduced fusogenic activity.

60 ding superinfection, fibroblast killing, and fusogenic activity.

61 y members (TMEM8a and TMEM8b) do not exhibit fusogenic activity.

62 e of purifying selection and conservation of fusogenic activity.

63 We investigated the effects of fusogenic agents by simply flowing these molecules into

64 es it possible to characterize rapidly novel fusogenic agents under well-defined conditions.

65 nts in the presence of low concentrations of fusogenic agents, when fusion was rare and probabilistic

66 ons resulted in proteins that were much less fusogenic, although they were equally well expressed at

67 rus spreads faster than MV-Edm and is highly fusogenic and a potent oncolytic.

68 H7 avian influenza virus hemagglutinin in a fusogenic and attenuated NDV background.

69 infects cells expressing MV receptors and is fusogenic and effective against myeloma xenografts in mi

70 The goal of this study was to map the fusogenic and lytic domains of SP-B and assess the effec

71 tides alter structure within the bilayers of fusogenic and nonfusogenic lipid vesicles and 2), how fu

72 but both increased acyl chain order in both fusogenic and nonfusogenic vesicles.

73 cially enveloped Ad using cationic, neutral, fusogenic, and PEGylated lipids to form the envelopes an

74 from persistently infected cells are highly fusogenic, and this phenotype has been mapped to two mut

75 VSV-FH is not fusogenic at low CD46 density but requires less CD46 for

76 olvent channels of BRV, which makes BRV like fusogenic avian orthoreoviruses and aquareoviruses but u

77 that BRV is like nonfusogenic mammalian and fusogenic avian orthoreoviruses in having 150 copies of

78 eld, faster replication kinetics, and larger fusogenic capabilities but should be used in cancer type

79 Here, we compared the fusogenic capacities between homologous and heterologous

80 ng negative correlation between the relative fusogenic capacities of these cytoplasmic-tail mutants a

81 Importantly, to accurately measure their fusogenic capacities, as these depend on glycoprotein ce

82 wn to contain determinants that affect their fusogenic capacities.

83 ed to acidify, although they retained normal fusogenic capacity with nascent phagosomes.

84 Consistent with the extinction of fusogenic capacity, both FUS1 and HAP2 are degraded upon

85 Fusogenic cells are exposed to biochemical and biophysic

86 r confer fusogenic activity to otherwise non-fusogenic cells.

87 Fusogenic changes involve assembly of two heptad repeats

88 the opportunity for low-efficiency fusion by fusogenic complexes incorporating BoNT/A-cleaved SNAP-25

89 The samples were prepared under fusogenic conditions and contained equimolar amounts of

90 layed ~80% of content release under the same fusogenic conditions.

91 These results indicate that activation to a fusogenic conformation is dependent on the interplay of

92 ffective even after hemagglutinin attained a fusogenic conformation or had induced membrane hemifusio

93 s during fusion using the beta-strand as the fusogenic conformation.

94 re part of the "pH sensor" that triggers the fusogenic conformational change in E, at the reduced pH

95 back, in a rearrangement that resembles the fusogenic conformational changes in enveloped-virus fusi

96 To gain insight into the nature of the fusogenic conformational changes in gB, we used several

97 that are very different from the large-scale fusogenic conformational changes in other viral fusion p

98 Further, HB80 inhibits the HA fusogenic conformational changes induced at low pH.

99 only the anti-SARS-CoV S antibody triggered fusogenic conformational changes via receptor functional

100 ls, but free monosaccharide does not trigger fusogenic conformational changes.

101 The reversibility of their fusogenic conformational transitions differentiates them

102 n different structures representing distinct fusogenic conformations help to explain how E protein (i

103 The fusogenic core assembly of human immunodeficiency virus

104 ns formed a six-helix bundle, similar to the fusogenic core structure of HIV-1 gp41.

105 nor can it inhibit the 6-HB formation of the fusogenic core.

106 mined that (a) TRPV4 is directly involved in fusogenic cytokine (interleukin-4 plus granulocyte macro

107 (d) TRPV4-Rac1 signaling axis is critical in fusogenic cytokine-induced FBGC formation.

108 tion is further augmented in the presence of fusogenic cytokines; (c) TRPV4-dependent activation of R

109 d not exhibit this RBE epitope were also non-fusogenic despite their ability to bind ephrinB2, oligom

110 usion intermediates that formed for the more fusogenic dioleoyl PC-containing liposomes did not inact

111 For less fusogenic distearoyl PC-containing liposomes at 4 degree

112 are excluded from these domains, could form fusogenic domains with Chol.

113 , we developed a transducible, pH-sensitive, fusogenic dTAT-HA2 peptide that markedly enhanced TAT-Cr

114 ifferent phases during initial generation of fusogenic E1 trimers.

115 is prevented and that direct coupling of the fusogenic ectodomain to branched actin assembly is suffi

116 facilitated the engagement of Irgm1 with its fusogenic effectors at the site of infection, thereby en

117 omplexin therefore cooperates with the other fusogenic elements of the synaptic fusion machinery duri

118 lated model to isolate druggable FC-specific fusogenic elements underlying RMS, which uncovered the E

119 Syncytins are fusogenic envelope (env) genes of retroviral origin that

120 Importance: Syncytin genes are fusogenic envelope genes of retroviral origin, ancestral

121 Syncytin genes are fusogenic envelope protein (env) genes of retroviral ori

122 It is fusogenic, expressed at the syncytialized placental mate

123 Thus, the fusogenic F protein resembles SNARE proteins involved in

124 recombinant NDV modified to contain a highly fusogenic F protein.

125 ggest that xlProminin-1 may serve as an anti-fusogenic factor in the regulation of disk morphogenesis

126 promoting vesicle-mediated translocation of fusogenic ferlin proteins to the plasma membrane.

127 h HA undergoes an irreversible switch to its fusogenic form in host endosomes, a crucial step for vir

128 essential for the generation of a mature and fusogenic form of the F protein.

129 rimerization is their likely topology in the fusogenic form of the intact gp41 protein.

130 in decreased cell surface expression of the fusogenic form, consistent with decreased stability of t

131 coat seems to be a specific conductor of the fusogenic forms of these SNAREs, suggesting how vesicle

132 n intermediate between the smooth mature and fusogenic forms.

133 nd cholesterol-independent structure for non-fusogenic FP-Hairpin was consistent with membrane insert

134 on of cholesterol-dependent FP structure for fusogenic FP34 and N70 and cholesterol-independent struc

135 de may be greatly simplified while retaining fusogenic function and minimizing membrane-permeablizing

136 Our work reveals that trout myomaker has fusogenic function despite containing two protein extens

137 ledge, this is the first attempt to optimize fusogenic function of the HIV fusion peptide through seq

138 domain that we hypothesize is essential for fusogenic function.

139 Thus, BNAbs disrupt HIV-1 MPER fusogenic functions critical for virus entry into human

140 n wild type but to a greater degree than non-fusogenic fusion domain mutants.

141 f interest in proteoliposomes containing the fusogenic galactose-terminated F-glycoprotein of the Sen

142 demonstrate that syncytium formation of the fusogenic gB/VSV-G chimera can be significantly inhibite

143 Expression of fusogenic genes is decreased, Pax7 upregulated, MuSCs ar

144 ed novel targets in myoblasts, including the fusogenic genes myomaker and myomixer.

145 ibosyltransferase fusion (Fcy::Fur)] and the fusogenic glycoprotein from gibbon ape leukemia virus (G

146 ecent work has suggested that gB is the sole fusogenic glycoprotein, regulated by interactions with t

147 Although gB is known to be a fusogenic glycoprotein, the mechanism by which gK is inv

148 ed a cell-based fusion assay to identify the fusogenic glycoproteins of CMV.

149 A hallmark of the fusogenic glycoproteins of these pathogens is refolding

150 epeat (NHR) and prevent the formation of the fusogenic gp41 core between viral gp41 NHR and CHR, ther

151 fusion rate with the total concentration of fusogenic HA trimers and indicates that more than one HA

152 relates the fusion rate with the fraction of fusogenic HA trimers and leads to the conclusion that on

153 ipates in fusion through interactions with a fusogenic HA.

154 t antibody binding prevents formation of the fusogenic hairpin conformation of E, which together with

155 brane and binds to the HRB helices to form a fusogenic hairpin.

156 The fusogenic human immunodeficiency virus type 1 (HIV-1) gp

157 required for the formation of a consolidated fusogenic hydrophobic surface at the tip of the FL.

158 ability (the length of time that they remain fusogenic in an acidic environment) at higher pHs, but t

159 features of a bona fide syncytin gene: It is fusogenic in an ex vivo cell-cell fusion assay; it is sp

160 ere stable in the presence of serum and were fusogenic in nature, with increased peptide alpha-helici

161 ggest that chlamydiae contained in small non-fusogenic inclusions will persist.

162 rgo large conformational rearrangements to a fusogenic intermediate and a more stable postfusion stat

163 DOPE promotes fusogenic, inverted hexagonal lipid structures while DOP

164 omprising cationic and neutral lipids plus a fusogenic lipid (PCat).

165 in vitro, those formulations containing the fusogenic lipid 1,2-dioleoyl-sn-3-phosphoethanolamine (D

166 ng peptides for selective tissue homing, and fusogenic lipid coatings to induce fusion with the plasm

167 n in synaptic vesicles and with an optimally fusogenic lipid composition.

168 atory lipids that includes diacylglycerol, a fusogenic lipid that is produced through multiple metabo

169 ectedly linked by the generation of a common fusogenic lipid.

170 comprising different amounts of cationic and fusogenic lipids (10-30mol% DOTAP or 1,2-dioleoyl-sn-gly

171 sis requires both SNARE-complex proteins and fusogenic lipids, such as phosphatidic acid.

172 A cell-penetrating peptide-modified fusogenic liposomal membrane was coated on the core, whi

173 osome-based co-delivery system composed of a fusogenic liposome encapsulating ATP-responsive elements

174 The fusogenic liposome had a protein-DNA complex core contai

175 somal ATP promoted the drug release from the fusogenic liposome in the acidic intracellular compartme

176 Traditionally, such fusogenic liposomes are prepared by mixing lipids and li

177 Here we prepared fusogenic liposomes in situ, i.e., by addition of a lipi

178 cholesterol modified peptides yielded highly fusogenic liposomes.

179 d 5, exhibited significantly lower levels of fusogenic, lytic, and surface tension reducing activitie

180 The fusogenic machinery in Drosophila, however, is understoo

181 lectively, our studies allow us to propose a fusogenic mechanism of genome delivery by STIV, in which

182 We used a similar approach to study the fusogenic mechanism of severe-acute-respiratory-syndrome

183 ertion mode is crucial for understanding its fusogenic mechanism.

184 41 provided crucial information on the viral fusogenic mechanism.

185 ng of normal prostate tissue in situ using a fusogenic membrane glycoprotein along with the immune ad

186 its the unique and powerful ability of viral fusogenic membrane glycoproteins (FMGs) to couple concen

187 tiveness of P/V mutants can be enhanced by a fusogenic membrane protein without compromising sensitiv

188 blast fusion and associates with Myomaker, a fusogenic membrane protein.

189 gh cell-cell fusion requires the presence of fusogenic membrane proteins and actin-dependent cytoskel

190 Viral fusogenic membrane proteins have been proposed as tools

191 athological syncytia, is typically driven by fusogenic membrane proteins with tall (>10 nm) ectodomai

192 n the first 2 h after infection than for the fusogenic MHVs.

193 e lipid bilayer fusion or fusion assisted by fusogenic molecules.

194 o configuration as well as the addition of a fusogenic motif yielded a far more potent and stable BCL

195 shed in four different cell types and with a fusogenic mutant, the S757R mutant, derived from isogeni

196 termediate between that of wild type and non-fusogenic mutants.

197 re predict that the kinked helix is the most fusogenic of these three conformations.

198 rial recruitment of DRP1 and down-regulating fusogenic optic atrophy 1 (OPA1) and mitofusins in rat g

199 ial entry mechanism is usually classified as fusogenic or endocytotic.

200 HA) from the native conformation to putative fusogenic or postfusion conformations populated at low p

201 droplets, with no restriction on the size of fusogenic partners.

202 ated by introducing point mutations in the F fusogenic peptide (G3A) or at a distal site near the F t

203 ring a nuclear localizing sequence SV40 or a fusogenic peptide (HIV-1Tat 40-60 or octa-arginine) link

204 To test the hypothesis that trimerization of fusogenic peptide is related to optimal fusion, we have

205 eveals key amino acid residues and a minimal fusogenic peptide motif that is necessary for promoting

206 As the N-terminal region of gp120, the fusogenic peptide of gp41, and the PTMR of gp41 show hig

207 The fusogenic peptide sequences HIV-1Tat 40-60 and octa-argi

208 properties of ccX31 versus the monomeric X31 fusogenic peptide.

209 rimer in a prefusion-like state at and below fusogenic pH.

210 Importantly, the fusogenic phenotypes of the glycoprotein combinations ne

211 iral entry levels primarily corroborated the fusogenic phenotypes of the glycoprotein pairs analyzed.

212 inetic curves that correlated with the NiV-F fusogenic phenotypes, validating NiVLPs as suitable vira

213 tes the perturbations, consistent with their fusogenic phenotypes.

214 A novel type of pH-sensitive, "fusogenic" pHLIP-liposomes was developed, which could be

215 ces in the six helix bundle structure of the fusogenic portion (gp41) of the HIV envelope glycoprotei

216 -activated gD, and (iii) upregulation of the fusogenic potential of gB following its interaction with

217 structural rearrangements and unleashing the fusogenic potential of gp41 to induce membrane fusion.

218 the most crucial trigger for unleashing the fusogenic potential of gp41.

219 specificity of PI(3,5)P(2) in regulating the fusogenic potential of intracellular organelles.

220 ted on the core, which had an acid-triggered fusogenic potential with the ATP-loaded liposomes or end

221 ression, Env incorporation into virions, Env fusogenic potential, and viral susceptibility to neutral

222 l columns, myc and VE-cadherin, in Notch1(-) fusogenic precursors, and bound to the myc promoter and

223 Our results suggest that SUPYN's anti-fusogenic properties may be exerted at several sites in

224 t the gK/UL20p protein complex modulates the fusogenic properties of gB and gH via direct physical in

225 olecule-1 (ICAM-1) augments the adhesive and fusogenic properties of myogenic cells.

226 may function to regulate the trafficking or fusogenic properties of the inclusion.

227 eras revealed differences in the budding and fusogenic properties of the M and G proteins, respective

228 For this reason synthetic lipids with fusogenic properties such as 2-dioleoyl-sn-glycero-3-pho

229 purifying selection and conservation of its fusogenic properties, over 30 millions years of evolutio

230 er muscle injury augments their adhesive and fusogenic properties, which, in turn, facilitates regene

231 The fusogenic property of ICAM-1-ICAM-1 interactions was res

232 It involves incorporation of antibody and fusogenic protein as two distinct molecules into the len

233 membrane protrusions, which in turn promoted fusogenic protein engagement and plasma membrane fusion.

234 led invasive membrane protrusions in driving fusogenic protein engagement during cell-cell fusion.

235 regional macrophages and altered the overall fusogenic protein expressions to regulate the macrophage

236 ed by epithelial fusion failure-1 (EFF-1), a fusogenic protein that functions at the membrane to merg

237 ducts and kinetics, rSOF is a heterodivalent fusogenic protein that uses a docking site to displace a

238 from the paramyxovirus parainfluenza virus 5 fusogenic protein, F, forms an N-terminal TM helix, whic

239 Both fusogenic proteins and actin cytoskeletal rearrangements

240 Because fusogenic proteins and lipids concentrate in a ring at t

241 Although cellular fusogenic proteins and the actin cytoskeleton are implic

242 p FRD member 1, envelope (ERVFRD1), encoding fusogenic proteins critical to human trophoblast syncyti

243 The role of the water-soluble regions of fusogenic proteins has been extensively studied, but the

244 Class I viral fusogenic proteins have an N-terminal hydrophobic fusion

245 Fusogenic proteins increase the intrinsically slow rate

246 protein receptor (SNARE)] complexes or viral fusogenic proteins that actively promote the development

247 Annexins are Ca(2+)-binding, membrane-fusogenic proteins with diverse but poorly understood fu

248 Fusogenic proteoliposomes, containing charged lipids and

249 ulti-domain site on PUUV Gc and may preclude fusogenic rearrangements of the glycoprotein that are re

250 The only exception to this dogma is the fusogenic reoviruses that encode fusion-associated small

251 Importantly, this fusogenic repair occurs in cells fully proficient for no

252 mpatibility appeared to be caused in part by fusogenic repression in MLV particles through an unknown

253 s as an important cofactor that promotes the fusogenic restructuring of pre-fusion complexes and like

254 We find that, even though the fusogenic sites support multi-cell adhesions, triploid z

255 avity in the HRA trimeric coiled coil in the fusogenic six-helix bundle (6HB) structure.

256 that is exposed between two C helices in the fusogenic six-helix bundle conformation of gp41.

257 ion by interfering with the formation of the fusogenic six-helix bundle structure.

258 gulates viral entry by assembling a specific fusogenic SNARE complex.

259 brane SNARE, syntaxin, for assembly into the fusogenic SNARE complex.

260 embly pathway that leads to formation of the fusogenic SNARE complex.

261 c vesicle secretion requires the assembly of fusogenic SNARE complexes.

262 to the cell division plane, transformed into fusogenic SNARE complexes.

263 al concept of how Sec24 isoforms can recruit fusogenic SNARE subunits to keep them functionally apart

264 to other class I viral fusion proteins, the fusogenic stalk domain spontaneously refolds into its po

265 ertion of independently folding domains into fusogenic stalk domains may be a common feature of class

266 Besides inducing the fusogenic state of hemagglutinin, low pH cues softened t

267 In the fusogenic state, this pocket is occupied by key amino ac

268 pproximately 2 log10 higher than that of the fusogenic strain A59 in astrocytoma DBT cells.

269 rstanding of the molecular basis of the gp41 fusogenic structural transitions and thereby guide ratio

270 ocytosis of ZGs resulting from a decrease in fusogenic STX-4 SNARE complexes.

271 Baboon reovirus (BRV) is a member of the fusogenic subgroup of orthoreoviruses.

272 esisting forces from fusion partners put the fusogenic synapse under high mechanical tension, which h

273 revealed dynamin along actin bundles at the fusogenic synapse.

274 human chorionic gonadotropin (hCG) beta] and fusogenic [syncytin 1, syncytin 2, and glial cells missi

275 Thus, a more fusogenic target membrane effectively blocks nonproducti

276 en adjacent membranes; it was, however, less fusogenic than Ca2+ at comparable concentrations.

277 do suggest that small oligomers may be more fusogenic than either monomers or large aggregates.

278 a cell-cell fusion assay, line 19 F was more fusogenic than Long F.

279 the fusion peptide (P/V-CPI(-)-G3A) was more fusogenic than the parental P/V-CPI(-) mutant.

280 a central TM region leucine (L507A) was more fusogenic than the unmodified F protein while retaining

281 the C terminus is required for Env to become fusogenic, this restriction of Env function may serve to

282 Because many viruses are fusogenic, this study suggests that viruses, including t

283 og 1B (Vti1b)], leading to the assembly of a fusogenic trans-SNARE complex involving vesicle-associat

284 Given that gp41 fusogenic transformation is characterized by the hexamer

285 However, the dynamic nature of the fusogenic trimer has made the determination of its struc

286 ers that are similar to the predicted "open" fusogenic trimer.

287 he reorganization of E protein monomers into fusogenic trimers in the acidic environment of endosomes

288 conditions, the mature virus forms transient fusogenic trimers of E glycoproteins that engage the lip

289 us has been captured during the formation of fusogenic trimers.

290 However, these fusogenic truncated Env mutants are inefficiently incorp

291 cell fusion can be achieved by engineering a fusogenic viral membrane glycoprotein complex.

292 influence morphogenesis to produce maximally fusogenic virus.

293 need for mechanisms to control the spread of fusogenic viruses in normal versus tumor cells.

294 The fusogenic VSV also conferred a significant survival adva

295 The results suggest that fusogenic VSV can be developed into an effective and saf

296 In vivo, administration of fusogenic VSV into the hepatic artery of Buffalo rats be

297 In vitro characterization of the recombinant fusogenic VSV vector on human and rat HCC cells showed e

298 The F protein of aMPV subtype A was highly fusogenic, whereas those from subtypes B and C were not.

299 t with endocytic compartments but instead is fusogenic with a subset of sphingomyelin-containing exoc

300 ubunits with Asp or Asn at position 324 were fusogenic with coreceptor chimeras containing either the