ライフサイエンスコーパス: galactose-1-phosphate

1 lyzes the conversion of alpha-d-galactose to galactose 1-phosphate.

2 yzing the conversion of alpha-d-galactose to galactose 1-phosphate.

3 dent phosphorylation of alpha-D-galactose to galactose 1-phosphate.

4 ity to hydrolyze inositol monophosphates and galactose 1-phosphate.

5 dine 5'-phosphoryl group from UDP-glucose to galactose 1-phosphate.

6 of galactose-related metabolites, including galactose-1-phosphate.

7 TP-dependent phosphorylation of galactose to galactose-1-phosphate.

8 UDP-galactose from uridine triphosphate and galactose-1-phosphate.

9 okinase (GALK), phosphorylating galactose to galactose-1-phosphate.

10 D-galactose (2 muM), galactitol (11 muM) and galactose 1-phosphate (0.1 mM), (corresponding to plasma

11 ounterparts, demonstrated elevated levels of galactose 1-phosphate and diminished UDP-gal upon exposu

12 ly reported structures of the Mg(2+)-alpha-d-galactose-1-phosphate-beta-PGM, Mg(2+)-phospho-beta-PGM,

13 requires conversion of GDP-L-galactose to L-galactose 1-phosphate by a previously unidentified enzym

14 IMPase to use both inositol 1-phosphates and galactose 1-phosphate equally as substrates is of consid

15 His residue with GDP-L-galactose, forming L-galactose 1-phosphate for vitamin C synthesis, and regen

16 f the guanylylated enzyme, forming GDP and L-galactose 1-phosphate from GDP-L-galactose and phosphate

17 sitol signaling, we found it also hydrolyzes galactose 1-phosphate (Gal 1-P), an intermediate of gala

18 Therefore, the specific detection of galactose 1-phosphate (Gal 1-P), galactose (Gal), and ur

19 e catalyzes the reaction of UDP-glucose with galactose 1-phosphate (Gal-1-P) to form UDP-galactose an

20 Accumulation of galactose-1 phosphate (gal-1P) is thought to be the majo

21 reversible transformation of UDP-glucose and galactose-1-phosphate (Gal-1-P) into UDP-galactose and g

22 In the second reaction, galactose-1-phosphate (gal-1-P) is bound, UDP-galactose

23 sphate (Glc1P), mannose-1-phosphate (Man1P), galactose-1-phosphate (Gal1P), fucose-1-phosphate, gluco

24 Galactose-1-phosphate (galactose-1-P) uridylyltransferas

25 y-dependent growth phenotype and accumulated galactose 1-phosphate, glucose 1-phosphate, and GDP-gluc

26 ctokinase (GALK1), the enzyme that generates galactose-1 phosphate, has been proposed as a novel stra

27 lyzes the conversion of GDP-L-galactose to L-galactose 1-phosphate in a reaction that consumes inorga

28 lyzes the conversion of GDP-L-galactose to L-galactose 1-phosphate in the first committed step of the

29 uridine 5'-diphosphate glucose (UDPGlc) and galactose-1-phosphate into uridine 5'-diphosphate galact

30 a) has similarity to IMP and can hydrolyze l-galactose 1-phosphate (l-Gal 1-P), suggesting that this

31 drial respiration was sufficient to diminish galactose-1-phosphate levels and, consequently, affects

32 tose exposure because the deletion decreases galactose-1-phosphate levels.

33 Six interconvertible 'core intermediates', galactose 1-phosphate <--> UDP-galactose <--> UDP-glucos

34 alactose and its metabolites, galactitol and galactose 1-phosphate, on oocyte quality as well as embr

35 e catalyzes the reaction of UDP-glucose with galactose 1-phosphate to form UDP-galactose and glucose

36 polysaccharide biosynthesis by transferring galactose-1-phosphate to a lipid carrier.

37 ate uridyltransferase (GALT), which converts galactose-1-phosphate + UDP-glucose to glucose-1-phospha

38 way for galactose metabolism (galactokinase, galactose-1-phosphate-uridyl transferase and UDP glucose

39 id 188 (Q188R) ablates the function of human galactose-1-phosphate uridyltransferase (GALT) and is th

40 on isoelectric focusing and 50% reduction in galactose-1-phosphate uridyltransferase (GALT) enzyme ac

41 Deficiency in the galactose-1-phosphate uridyltransferase (GALT) enzyme re

42 In humans, the absence of galactose-1-phosphate uridyltransferase (GALT) leads to

43 Galactosemia I results from loss of galactose-1-phosphate uridyltransferase (GALT), which co

44 od cell (RBC) UDPgalactose concentrations in galactose-1-phosphate uridyltransferase-deficient patien

45 epared enzymatically using galactokinase and galactose-1-phosphate uridyltransferase.

46 lethal disease caused by the dysfunction of galactose 1-phosphate uridylyltransferase (GALT).

47 re disease caused by inherited deficiency of galactose-1 phosphate uridylyltransferase (GALT).

48 Galactose-1-phosphate uridylyltransferase (GALT) acts by

49 Galactose-1-phosphate uridylyltransferase (GalT) catalyz

50 Galactose-1-phosphate uridylyltransferase (GalT) catalyz

51 The active site of galactose-1-phosphate uridylyltransferase (GALT) include

52 Impairment of the human enzyme galactose-1-phosphate uridylyltransferase (GALT) results

53 of Fhit-related hydrolases, and a branch of galactose-1-phosphate uridylyltransferase (GalT)-related

54 tion that results from partial impairment of galactose-1-phosphate uridylyltransferase (GALT).

55 Impairment of the human enzyme galactose-1-phosphate uridylyltransferase (hGALT) result

56 Galactose-1-phosphate uridylyltransferase catalyzes the

57 Galactose-1-phosphate uridylyltransferase catalyzes the

58 y and contrast between the roles of GALE and galactose-1-phosphate uridylyltransferase in galactose m

59 Galactose-1-phosphate uridylyltransferase plays a key ro

60 pplied a yeast coexpression system for human galactose-1-phosphate uridylyltransferase, a dimeric enz

61 second enzyme of the Leloir pathway, namely galactose-1-phosphate uridylyltransferase, alternate for

62 eoside monophosphate transferases, including galactose-1-phosphate uridylyltransferase, diadenosine t

63 ed by the chain-fold similarities of Fhit to galactose-1-phosphate uridylyltransferase, which functio

64 The chain fold of Fhit is similar to that of galactose-1-phosphate uridylyltransferase, which functio

65 strate recognition and binding in the native galactose-1-phosphate uridylyltransferase.

66 d by a naturally occurring mutation in human galactose-1-phosphate uridylyltransferase.

67 otif that is reminiscent of the HPH motif in galactose-1-phosphate uridylyltransferases, in which the