ライフサイエンスコーパス: gastric emptying

1 tiatives should in addition focus on delayed gastric emptying.

2 han increasing the energy density in slowing gastric emptying.

3 The primary end point was the half-time of gastric emptying.

4 c clinical syndrome characterized by delayed gastric emptying.

5 effect on postprandial glucose, insulin, and gastric emptying.

6 instability was associated with a change in gastric emptying.

7 oesophageal reflux, constipation and delayed gastric emptying.

8 thers documenting a GLP-2-dependent delay in gastric emptying.

9 Acute GLP-1 markedly slowed gastric emptying.

10 tially improved glucose tolerance and slower gastric emptying.

11 the intestine by regulating food intake and gastric emptying.

12 nes, suggesting that PDE4 inhibition impairs gastric emptying.

13 /- 0.6%) on insulin pump therapy with normal gastric emptying.

14 ational treatments of disorders with delayed gastric emptying.

15 cerebroventricularly significantly decreased gastric emptying.

16 d for prevention of diabetes-induced delayed gastric emptying.

17 during the muscular contractions leading to gastric emptying.

18 sex, body mass, symptom onset, and delay in gastric emptying.

19 ature infants, may play a functional role in gastric emptying.

20 hat were resistant to development of delayed gastric emptying.

21 tyrosine kinase Kit, are required for normal gastric emptying.

22 lly antagonized GLP-1-induced delay of solid gastric emptying.

23 -3000 pmol) dose-dependently inhibited solid gastric emptying.

24 erity of symptoms were predictive of delayed gastric emptying.

25 esulted in higher glucagon levels and faster gastric emptying.

26 asting, and to search for a correlation with gastric emptying.

27 elate symptoms of gastroparesis with IMD and gastric emptying.

28 ration with bedside functional assessment of gastric emptying.

29 bers of gastric dopamine neurons and delayed gastric emptying.

30 however, increase meal size and accelerated gastric emptying.

31 Nevertheless, it may also lead to delayed gastric emptying.

32 bohydrates, 15 g protein, and 12 g fat), and gastric emptying ((13)C-acetate breath test) and blood g

33 emorrhage (9.1% vs 5.1%, P = 0.352), delayed gastric emptying (21.2% vs 22.4%, P = 0.930), bile leaka

34 ms of gastroparesis, 129 (72.9%) had delayed gastric emptying; 25 (14.1%) had abnormal IMD(0) Low IMD

35 er 180 min, appetite (visual analog scales), gastric emptying (3-dimensional ultrasonography), and bl

36 nic heterotypic stress significantly delayed gastric emptying (35.1+/-2.8%, n=6, P<or=0.01), compared

37 Particularly the times of 10% gastric emptying, 50% gastric emptying, maximal intestin

38 ransit slowed in mice lacking TPH2 mice, but gastric emptying accelerated.

39 xytocin is involved in restoring the delayed gastric emptying after paired housing, an oxytocin antag

40 tor activity and urocortin 2-induced delayed gastric emptying also indicate a safe and long-lasting a

41 eficits in olfactory discrimination, delayed gastric emptying, altered sleep latency, anxiety-like be

42 ces postprandial glycemia, partly by slowing gastric emptying, although its impact on small intestina

43 here was a protein load-dependent slowing of gastric emptying, an increase in concentrations of insul

44 Ten percent gastric emptying and 50% gastric emptying were decreased

45 n, whey-protein drinks load-dependently slow gastric emptying and alter gut hormone secretion compare

46 tivity, and beta-cell mass, while inhibiting gastric emptying and appetite.

47 dures under general anesthesia have impaired gastric emptying and are at high risk for aspiration of

48 duced, MIDP was associated with less delayed gastric emptying and better quality of life without incr

49 Delayed gastric emptying and bile reflux are common concerns in

50 tor-mediated response) and did not influence gastric emptying and blood pressure (CRF2 receptor-media

51 Gastric emptying and colonic transit were scintigraphica

52 ooling and swallowing problems, to delays in gastric emptying and constipation.

53 d and to determine the relationships between gastric emptying and dyspeptic symptoms in inactive CD.

54 GLP-1 also modulates gastric emptying and engages neural circuits in the port

55 Both processes also control gastric emptying and gastrointestinal secretions.

56 At 6 h, gastric emptying and gastrointestinal transit assessed i

57 anical responses, gastric motility patterns, gastric emptying and GI transit.

58 -induced insulin secretion and inhibits both gastric emptying and glucagon secretion.

59 mittent stimulation of the GLP-1 receptor on gastric emptying and glycemia.

60 AN have slower gastric emptying and heightened visceral perception comp

61 TNX-deficient mice have accelerated gastric emptying and hypersensitivity of gastric vagal m

62 Slowed gastric emptying and improved oral glucose tolerance pro

63 o uncoordinated antral contractions, delayed gastric emptying and increased total GI transit time.

64 aximal intestinal filling, indicating faster gastric emptying and intestinal filling.

65 TNX deficient mice had accelerated gastric emptying and markedly increased vagal afferent r

66 Gastric emptying and meal appearance did not differ betw

67 Inclusion criteria included delayed gastric emptying and moderate to severe symptom scores u

68 animals in which effects of reduced Ano1 on gastric emptying and motor patterns could not be evaluat

69 Gastric emptying and nutritional status were maintained

70 between the viscosity and energy density on gastric emptying and perceived satiety.

71 Ghrelin promotes gastric emptying and secretion of growth hormone and inh

72 promoting growth of the mucosa and reducing gastric emptying and secretion.

73 0 mug twice daily) significantly accelerated gastric emptying and significantly reduced vomiting, com

74 SG accelerates gastric emptying and small bowel transit of semisolids.

75 inal glucose transport but rather inhibiting gastric emptying and small intestine motility and strong

76 gical evidence for involvement of TMEM16A in gastric emptying and suggest the utility of TMEM16A inhi

77 n the autonomic nervous system regulation of gastric emptying and that PDE4 inhibitors that are not b

78 Gastric emptying and volumes and satiation were not sign

79 Gastric emptying and volumes, postprandial symptoms, tot

80 relin significantly reduced the half-time of gastric emptying and vomiting, as well as nausea, abdomi

81 Appetite, gastric-emptying and orocecal transit times, and selecte

82 er and lower fullness sensations, more rapid gastric-emptying and orocecal transit times, attenuated

83 ther digestive symptoms, nutritional status, gastric emptying, and control of diabetes.

84 to improve dietary absorption of fats, slow gastric emptying, and decrease food intake.

85 amate caused significant weight loss, slowed gastric emptying, and decreased calorie intake; weight l

86 with normal emptying, diabetic with delayed gastric emptying, and diabetic with delayed gastric empt

87 y weight, body mass index, body composition, gastric emptying, and genetic variation (alpha2A C1291G,

88 of resveratrol treatment on GLP-1 secretion, gastric emptying, and glycemic control in type 2 diabete

89 of whey protein on energy intake, appetite, gastric emptying, and gut hormones in healthy older men

90 equency, impaired glucose tolerance, delayed gastric emptying, and increased body weight compared to

91 fasting and postprandial glucose, decreases gastric emptying, and inhibits food intake in a GLP-1 re

92 f 4 sweet preloads on GIP and GLP-1 release, gastric emptying, and postprandial glycemia.

93 ndent insulinotropic polypeptide (GIP), slow gastric emptying, and reduce postprandial glycemic excur

94 cluding esophageal transit, liquid and solid gastric emptying, and small- and large-bowel transit, us

95 Gastric emptying, antral contractions and oro-cecal tran

96 responses, but whether OBG viscosity affects gastric emptying, appetite, and ad libitum food intake i

97 There was no effect of sex on gastric emptying, appetite, gastrointestinal symptoms, g

98 Pasteurization did not affect gastric emptying ( approximately 30-min half time) or pH

99 ncentration of glucose (P<0.001) and delayed gastric emptying as revealed by the acetaminophen absorp

100 A relationship between body weight and gastric emptying as well as self-reported feelings of sa

101 Gastric emptying, as assessed following an oral bolus of

102 with moderate to severe symptoms and delayed gastric emptying at 27 clinical centers, from June 2012

103 This resulted in delayed gastric emptying, at least partially caused by impaired

104 effect on GLP-1 secretion, glycemic control, gastric emptying, body weight, or energy intake.

105 On a separate day, all patients underwent a gastric emptying breath test with assessment of postpran

106 glucose and plasma GLP-1 concentrations and gastric emptying (breath test) over 240 min.

107 food intake, hindbrain c-fos expression, or gastric emptying but improved glucose tolerance and stim

108 Current data indicate faster postoperative gastric emptying, but detailed studies on alterations in

109 .33 mum) compared with LE2 (52 mum)] delayed gastric emptying by 38 min.

110 , we measured plasma GH, gastric volume, and gastric emptying by combined (99m)Tc-single-photon emiss

111 roparesis, typical symptoms alone or delayed gastric emptying by scintigraphy without gastrointestina

112 re used: (1) definite gastroparesis, delayed gastric emptying by standard scintigraphy and typical sy

113 ibition of HO-1 activity in mice with normal gastric emptying caused a loss of Kit expression and dev

114 These tests include measures of gastric emptying; contractility; electrical activity; re

115 e whether alterations in meal absorption and gastric emptying contribute to the mechanism by which in

116 ed, 105 (24.4%) of whom demonstrated delayed gastric emptying defined by 4-h gastric retention of mor

117 The primary outcome was change in gastric emptying (delay relative to baseline) of solids

118 ) mice after onset of diabetes, when delayed gastric emptying develops, and after induction of HO1 to

119 pancreatectomy hemorrhage (PPH), and delayed gastric emptying (DGE) were also graded.

120 operative pancreatic fistula (POPF), delayed gastric emptying (DGE), postpancreatectomy hemorrhage (P

121 Onset of delayed gastric emptying did not alter the total number of macro

122 n gastric emptying of solids; measurement of gastric emptying (eg, at 5 weeks of treatment) may be a

123 e, percentage emptying at 10 s), liquid-only gastric emptying (emptying half-time), liquid and solid

124 These changes include accelerated gastric emptying, enhanced postprandial cholecystokinin

125 lated in all the mice that developed delayed gastric emptying; expression of Kit and neuronal nitric

126 Social attachment restores delayed gastric emptying following chronic heterotypic stress, v

127 es physical resistance of the dosage form to gastric emptying forces, which are known to be stronger

128 The acute effects of lipid emulsions on gastric emptying, gallbladder volume, and triglyceride a

129 in the physiologic range) versus placebo on gastric emptying, gastric volume, and postprandial sympt

130 udy was to evaluate the long-term outcome of gastric emptying, gastrointestinal symptoms and nutritio

131 lack of association between improvements in gastric emptying (GE) and upper gastrointestinal (UGI) s

132 the efficacy of relamorelin on symptoms and gastric emptying (GE) in a 12-week, phase 2B study of di

133 mula is thought to play an important role on gastric emptying (GE) in a variety of gastrointestinal d

134 Delayed gastric emptying (GE) induced by acute restraint stress

135 approximately 20% of patients with diabetes, gastric emptying (GE) is accelerated.

136 relationship between control of glycemia and gastric emptying (GE) is unclear.

137 Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit s

138 Glucagon was suppressed, and gastric emptying (GE) was decelerated.

139 fects of antidepressant therapy on symptoms, gastric emptying (GE), and meal-induced satiety in patie

140 e use of mathematical modeling, we estimated gastric emptying, glucose absorption, beta-cell function

141 Delayed gastric emptying grade B/C was seen less often after MID

142 adequate endogenous GLP-1 release, requiring gastric emptying >2 kcal/min; and 3) the action of metfo

143 Severe delay in gastric emptying (>35% retention at 4 hours) was present

144 Delayed gastric emptying had the greatest independent impact on

145 Patients with severely delayed gastric emptying had worse vomiting and more severe loss

146 Overall, the gastric emptying half-time (GE t50) was 54.7 +/- 3.8 min

147 tying of solids and liquids by scintigraphy (gastric emptying half-time [GE t(1/2)]); gastric volumes

148 incremental area-under-the-curve and delayed gastric-emptying half-time (geometric mean: 285; 95% CI:

149 to determine whether a study of clear liquid gastric emptying has added value for the diagnosis of ga

150 astroparesis, a 30-min study of clear liquid gastric-emptying has considerable added diagnostic value

151 associated with alterations in the rates of gastric emptying, impaired accommodation, heightened gas

152 eal (500 kcal) in 13 women without affecting gastric emptying in 6 women.

153 nthase expression, and completely normalized gastric emptying in all mice.

154 ous studies assessing the effect of GLP-2 on gastric emptying in humans have yielded inconsistent res

155 Delayed gastric emptying in inactive Crohn's disease patients se

156 oxytocin antagonist attenuated the restored gastric emptying in paired housed rats (33.2+/-4.1%, n=6

157 agonist of the ghrelin receptor that speeds gastric emptying in patients with diabetes) in patients

158 Y(3-36) [PYY(3-36)] inhibit, food intake and gastric emptying in rats.

159 abscess was detected in one patient, delayed gastric emptying in six patients, anastomotic leakage fr

160 l (180-210 min; energy intake, appetite, and gastric emptying in the men have been published previous

161 apsule successfully detected acceleration of gastric emptying induced by erythromycin, and retardatio

162 e of post-pancreatectomy hemorrhage, delayed gastric emptying, infectious complications, the grade of

163 is identified as the main mechanism by which gastric emptying is increased; some motilin agonists act

164 While gastric emptying is probably the most significant compon

165 Diabetic gastroparesis (delayed gastric emptying) is a well-recognized complication of d

166 Gastroparesis, a condition of abnormal gastric emptying, is most commonly observed in diabetic

167 afferent neurons to inhibit food intake and gastric emptying; it also increases expression of the ne

168 larly the times of 10% gastric emptying, 50% gastric emptying, maximal intestinal filling, 10% termin

169 We simultaneously measured gastric emptying, meal appearance, endogenous glucose pr

170 No significant change was found in gastric emptying (median half-time 137 vs. 132 vs. 125 m

171 es, abnormal phasic contractions and delayed gastric emptying; modest changes were noted in the small

172 nfectious complications (n = 65) and delayed gastric emptying (n = 29).

173 Delayed gastric emptying observed in singly housed rats induced

174 Delayed gastric emptying occurs in critically ill patients and i

175 The purpose of this study was to quantify gastric emptying of 30 and 70 g of oral whey protein loa

176 Gastric emptying of a mixed nutrient liquid meal was ass

177 Gastric emptying of a non-nutrient liquid was also deter

178 Gastric emptying of a radiolabeled mashed potato meal wa

179 tion, GLP-1 receptor blockade did not affect gastric emptying of a solid meal.

180 gastrointestinal transit and recipient solid gastric emptying of chrome steel balls, and marked preve

181 No significant differences in gastric emptying of liquids (acetaminophen area under th

182 glutide 4 mg/day for 10 days does not affect gastric emptying of liquids in healthy subjects as measu

183 y was to assess the effect of teduglutide on gastric emptying of liquids in healthy subjects, as meas

184 pants weighing less than 137 kg, we measured gastric emptying of solids and liquids by scintigraphy (

185 In a prospective study, we measured gastric emptying of solids and liquids, fasting and post

186 Compared with placebo, liraglutide delayed gastric emptying of solids at 5 weeks (median 70 min [IQ

187 Post-hoc analysis showed that the T1/2 of gastric emptying of solids at 5 weeks correlated with ch

188 Then, we propose to investigate whether gastric emptying of solids in patients with inactive CD

189 Gastric emptying of solids was analysed by the [13C]octa

190 On 3 separate days, we measured gastric emptying of solids, gastric volumes, postprandia

191 on weight loss are associated with delay in gastric emptying of solids; measurement of gastric empty

192 Gastric emptying of the L and H drinks was comparable wh

193 icate that, in healthy lean men, the rate of gastric emptying of whey protein is independent of load

194 inistration of leucine and isoleucine on the gastric emptying of, and blood glucose responses to, a p

195 The potential influence of gastric emptying on the "incretin effect," mediated by g

196 out diabetes, although it did not accelerate gastric emptying or increase of quality of life.

197 ministration of AITC by gavage did not alter gastric emptying or small intestinal transit, but lumina

198 Vildagliptin does not alter gastric emptying or the rate of entry of ingested glucos

199 385 mL, 95% CI = -616 to -154), less delayed gastric emptying (OR = 0.6, 95% = CI 0.5-0.8), and short

200 postprandial minus fasting) gastric volumes, gastric emptying, or aggregate postprandial symptoms.

201 ected glucagon, GLP-1, GIP, cholecystokinin, gastric emptying, or energy intake.

202 asting gastric volume (P = .03), accelerated gastric emptying (P < .001 for solids and P = .011 for l

203 -daily relamorelin significantly accelerated gastric emptying (P < .03) and reduced vomiting frequenc

204 soleucine-10g, but not isoleucine-5g, slowed gastric emptying (P < 0.05), but gastric emptying was no

205 in patients with delayed (P < .01) or normal gastric emptying (P = .05).

206 0.199), biliary leakage (P = 0.382), delayed gastric emptying (P = 0.062), burst abdomen (P = 0.480),

207 ng was significantly associated with delayed gastric emptying (p<0.05).

208 o drain placement for: DSM, CR-POPF, delayed gastric emptying, percutaneous drainage, length of stay,

209 Results based on standard 4-h solid gastric emptying, performed according to current Society

210 Although there was no difference in gastric emptying, plasma 3-O-methyl-glucose concentratio

211 uring the gastric phase, which led to faster gastric emptying, rapid intestinal hydrolysis, and highe

212 Liquid gastric emptying rate (GE) and antral motility parameter

213 Gastric protein hydrolysis may influence gastric emptying rate and subsequent protein digestibili

214 volume was linearly correlated to increased gastric emptying rate as well as increased GLP-1 respons

215 A slower eating rate and a delayed gastric emptying rate can partly explain for the stronge

216 Gastric emptying rate of protein was a significant (p<0.

217 Gastric emptying rates and nutritional statuses were eva

218 GLP-1R agonists also decelerate gastric emptying, reduce body weight by reduction of foo

219 Stress impairs gastric emptying, reduces stomach compliance and induces

220 tration dependent insulin secretion, slowing gastric emptying, reducing food intake and stimulating b

221 substrates stimulate GLP-1 and GIP and slow gastric emptying, regardless of whether they are metabol

222 median rate (95th upper normative limit) of gastric emptying, reported as total gastric meal retenti

223 gastric emptying, and diabetic with delayed gastric emptying reversed by the HO1 inducer hemin.

224 functions, which include insulin secretion, gastric emptying, satiety, and the hedonic aspects of fo

225 Heart rate variability measurements and gastric emptying scintigraphies were performed in all su

226 intragastric meal distribution (IMD) during gastric emptying scintigraphy (GES) allows for a simple

227 Pseudoachalasia, peptic ulcer, normal gastric emptying scintigraphy (GES) and prepyloric tumor

228 dard (99m)Tc-sulfur colloid ((99m)Tc-SC) for gastric emptying scintigraphy (GES).

229 Gastric emptying scintigraphy is considered to be the go

230 the Block Food Frequency Questionnaire, and gastric emptying scintigraphy results were analyzed.

231 istories, symptom questionnaires, and 4-hour gastric emptying scintigraphy studies were obtained from

232 f radiolabeled test meals have been used for gastric emptying scintigraphy.

233 Gastric emptying (scintigraphy, 100 mL of Ensure (Abbott

234 Smn deficiency caused constipation, delayed gastric emptying, slow intestinal transit and reduced co

235 eurons are reflected functionally in delayed gastric emptying, slowed colonic motility, and prolonged

236 f continuous or bolus nasogastric feeding on gastric emptying, small bowel water content, and splanch

237 In live mice, we measured total GI transit, gastric emptying, small intestinal transit, and propulsi

238 ater-only gastric emptying, water-with-solid gastric emptying, small-bowel transit, and colonic trans

239 ke peptide 1 (GLP-1), which is known to slow gastric emptying, stimulate insulin secretion, and suppr

240 unction alterations, including inhibition of gastric emptying, stimulation of colonic propulsive moti

241 dies can be performed alone or together with gastric emptying studies after oral administration of an

242 tudy was to evaluate the prognostic value of gastric emptying studies on the morbidity associated wit

243 The medical literature states that solid gastric-emptying studies are more sensitive for the dete

244 Gastric-emptying studies have no accepted standard metho

245 101 patients underwent both solid and liquid gastric-emptying studies, acquired sequentially on the s

246 ndards to diagnose gastroparesis utilizing a gastric emptying study as the key diagnostic modality bu

247 all patients who had completed a 4-h, solid gastric emptying study over the course of a 3 year perio

248 A delayed radionucleotide gastric emptying study predicts negative health outcomes

249 All patients underwent esophageal manometry, gastric emptying study, and sham-feeding test (correspon

250 n of the study, participants scheduled for a gastric emptying study, completed a modified GCSI questi

251 d intracerebroventricularly (icv) before the gastric emptying study.

252 , and retching) and delay in radionucleotide gastric emptying study.

253 A liquid-only 30-min gastric-emptying study followed, with ingestion of 3.7 M

254 Gastric emptying, subjective appetite, and glucose, insu

255 EM16A inhibition in disorders of accelerated gastric emptying, such as dumping syndrome, and potentia

256 ase Activity Index (CDAI) < 150, underwent a gastric emptying test by breath test using 13C octanoic

257 Advances in gastric emptying testing include wireless motility capsu

258 odified oral glucose tolerance test, but not gastric emptying testing, is useful for diagnosis.

259 r hospital stay and a higher rate of delayed gastric emptying than patients in the non-SSI group.

260 trointestinal hormone capable of stimulating gastric emptying, the relatively recent availability of

261 and energy content have been shown to delay gastric emptying, their relative importance is not well

262 in oxidative stress, and loss of Kit delays gastric emptying; this effect is reversed by induction o

263 s motility capsule to detect drug effects on gastric emptying time (GET) and gastric contractility.

264 The gastric emptying time and small intestinal motility were

265 New onset esophageal dysmotility, delayed gastric emptying time, and abnormal sham-feeding tests w

266 disease duration, severity of constipation, gastric emptying time, and heart rate variability.

267 here was no significant difference in either gastric emptying time--23 minutes (range 5-131) in patie

268 Faster gastric-emptying times were significantly associated wit

269 Consequent to the delay in gastric emptying, TM(inh)-23 administration significantl

270 rders, such as failure to thrive and delayed gastric emptying, together accounted for 58.9% of all re

271 ecently showed that central CRF delays solid gastric emptying via sympathetic pathways in rats.

272 Gastric emptying was accelerated in the sleeve gastrecto

273 Severe delay in gastric emptying was associated with more severe symptom

274 Normalization of gastric emptying was associated with repopulation of CD2

275 When gastric emptying was bypassed by direct glucose administ

276 the varying degree of stomach filling during gastric emptying was compared between groups.

277 Gastric emptying was delayed in 20% of patients at 2 h a

278 Solid gastric emptying was measured after 7 consecutive days o

279 Gastric emptying was measured in nonobese diabetic mice

280 ollected for hormone concentrations, whereas gastric emptying was measured via an isotope breath test

281 Gastric emptying was not accelerated during the ON perio

282 -5g, slowed gastric emptying (P < 0.05), but gastric emptying was not correlated with the blood gluco

283 Gastric emptying was not significantly different across

284 -treated rats ingested food at a lower rate, gastric emptying was not significantly different between

285 Delayed gastric emptying was produced by structurally distinct P

286 Gastric emptying was slower after both 3OMG and TIM than

287 ter of radioactivity >/=2 on day 3), but not gastric emptying, was significantly correlated with clin

288 obtained for esophageal transit, water-only gastric emptying, water-with-solid gastric emptying, sma

289 Ten percent gastric emptying and 50% gastric emptying were decreased postoperatively as well

290 asma total GLP-1 and GIP, serum insulin, and gastric emptying were determined.

291 od glucose and plasma total GLP-1 as well as gastric emptying were similar at each assessment, and th

292 o infection, nutritional status, and delayed gastric emptying were the most common reasons for readmi

293 spepsia had significantly (p<0.05) prolonged gastric emptying when compared to patients without dyspe

294 The impact of variations in gastric emptying, which influence the magnitude of gluco

295 ike peptide 1 (GLP-1) and its agonists slows gastric emptying, which represents the major mechanism u

296 hs of continuous symptoms of CUNV but normal gastric emptying who were treated at the University of M

297 A standardized method for measuring gastric emptying with a Tc(99m)-labelled meal followed b

298 Gastric emptying (with the use of 3-dimensional ultrasou

299 d 4 (ID4) kcal/min (equating to two rates of gastric emptying within the physiological range) on the

300 each of the two cheese meals, differences in gastric emptying would not explain the difference in leu

301 reatectomy hemorrhage, bile leakage, delayed gastric emptying, wound infection, and pneumonia) with e