ライフサイエンスコーパス: genealogical

1 Genealogical analyses inferred migration patterns throug

2 Microsatellite and genealogical analyses of eight separate European kindred

3 This application of genealogical analyses provides markedly stronger inferen

4 rent loci in the virus genome restricted the genealogical analyses to haplotypes with common mutation

5 Methods Haplotype and genealogical analyses were performed on 3 recurrent TTNt

6 Genealogical analysis resolved two distinct clusters of

7 e mode in a genome-wide phylogeny, but local genealogical analysis revealed numerous small genomic re

8 yses, using imputation, logistic regression, genealogical analysis using the GENECLUSTER program and

9 and coalescence records as the key units of genealogical analysis.

10 humans is defined as an individual who is a genealogical ancestor of all present-day people, the mos

11 e still expected to share millions of common genealogical ancestors over the last 1,000 years.

12 etic ancestors are a tiny fraction of common genealogical ancestors, individuals from opposite ends o

13 resent-day human has exactly the same set of genealogical ancestors.

14 o conduct one of the first surveys of recent genealogical ancestry over the past 3,000 years at a con

15 Genealogical and clinical record review, together with t

16 he posterior probability distribution of the genealogical and demographic parameters can be estimated

17 e strains is incomplete, we propose that all genealogical and genetic data on inbred strains be submi

18 e use importance sampling first to propose a genealogical and mutational history consistent with the

19 In the genealogical and phylogenetic analyses that are reported

20 surnames, it may have important forensic and genealogical applications.

21 ver, as these technical issues are solved, a genealogical approach holds great promise for understand

22 e disease and illustrates the utility of the genealogical approach in population genetics.

23 tions hinder the widespread application of a genealogical approach to plant evolutionary studies.

24 A genealogical approach utilizing hierarchical analysis of

25 When this genealogical approach was applied to the nucleotide sequ

26 The expected pattern of LD is predicted by a genealogical approach.

27 recombination necessitated that we also use genealogical approaches that can take advantage of both

28 , then characterized hybrid ancestries using genealogical assignment tests.

29 a has focused on the medical, phenotypic and genealogical associations of single nucleotide polymorph

30 dy of biological complexity beyond the usual genealogical bonds, revealing additional sources of biod

31 Three major genealogical clades of the 33 P. longifolia S alleles we

32 marker-by-marker coancestry, and least using genealogical coancestry.

33 y diverse samples that vary in both size and genealogical complexity.

34 Our findings underscore the importance of genealogical concordance analysis for species circumscri

35 Genealogical concordance and mating experiments were per

36 lated with the Fg complex phylogeny based on genealogical concordance at six single-copy nuclear gene

37 Spiroplasma, and find that it shows perfect genealogical congruence with the neo-W, suggesting that

38 parently unrelated individuals with no known genealogical connection to the original kindred.

39 dentify relatives up to the sixth degree and genealogical connections between archaeological groups.

40 ing in vitro to track the division speed and genealogical connections of all descendants derived from

41 as identity-by-descent (IBD), reveal recent genealogical connections.

42 The genealogical consequences of within-generation fecundity

43 When considered in a genealogical context, relationships among the G3pdh hapl

44 ody function in Drosophila are indicative of genealogical correspondence and thus an ancestral presen

45 y is The Netherlands, with a higher level of genealogical coverage relative to the population.

46 ry is the German Empire, with a low level of genealogical coverage relative to the total population s

47 The extensive genealogical data available for the population allowed a

48 Therefore, examination of these genealogical data can provide insights into the evolutio

49 Haplotype and genetic genealogical data defined MYBPC3 c.927-2A>G as a founder

50 Oxygen saturation and genealogical data were collected from residents of 905 h

51 e Utah Population Database, which links Utah genealogical data with Utah cancer data, we examined ris

52 eighteenth-nineteenth century pre-industrial genealogical dataset from Finland to investigate whether

53 Analysis of a Dutch genealogical dataset spanning the past 4 centuries revea

54 ity dynamics of males in familinx, a popular genealogical dataset, are representative of the general

55 result is consistent with differences in the genealogical depth of local genomic regions, a finding t

56 n repeat number was significant across three genealogical depths, suggesting that longer microsatelli

57 re a common genetic heritage, each being the genealogical descendant of a single species from the dis

58 with Bayesian analyses that account for both genealogical descent and geographical proximity.

59 efore central to fields that examine and use genealogical descent.

60 f mitochondrial and plastid genomes revealed genealogical differences both between these organelles a

61 theses, the gene trees reveal high levels of genealogical discordance associated with multiple primat

62 mes, to characterize patterns of genome-wide genealogical discordance, and to investigate demographic

63 The genealogical distortions are all maximized when the sele

64 ect imported cases, as they have a different genealogical distribution than that of locally acquired

65 sses that have given rise to them; here, the genealogical framework of the coalescent will continue t

66 Because the genealogical generations specifying kinship relations ar

67 dy heuristic algorithm for finding plausible genealogical histories (ancestral recombination graphs)

68 different parents, resulting in a mosaic of genealogical histories across the genome, which can be r

69 By measuring the average distance over which genealogical histories are typically preserved, these da

70 00 Genomes Project haplotypes produces joint genealogical histories for 26 human populations.

71 ancestral recombination graphs, which encode genealogical histories of DNA sequence data at each site

72 enetic data set in which all of the possible genealogical histories of the data are considered, each

73 d genetic linkage cause DNA segments to have genealogical histories resembling those of the selected

74 ealogical inference that samples independent genealogical histories using importance sampling (IS) an

75 ferent parts of the genome to have different genealogical histories.

76 ucity that has hindered inferences about the genealogical history and evolutionary development of the

77 termining the amount of recombination in the genealogical history of a sample of genes is important t

78 combination Graph (ARG), which describes the genealogical history of a sample of genomes, is a vital

79 Inferring the full genealogical history of a set of DNA sequences is a core

80 The recent genealogical history of human populations is a complex m

81 The genealogical history of microsatellite data sampled from

82 We assessed the genealogical history of P. infestans using sequences fro

83 how movement between populations shapes the genealogical history of sampled individuals and thereby

84 The genealogical history of the inbred lines is usually well

85 ave experienced at least one mutation in the genealogical history of the sample.

86 and does not explicitly model the underlying genealogical history of the study sample.

87 ontrasting mutational dynamics and of shared genealogical history on the correlation between polymorp

88 xperienced at most one mutation event in its genealogical history, which becomes less tenable for ver

89 mary determinant of these patterns is shared genealogical history.

90 n for a detailed reconstruction of Ashkenazi genealogical history.

91 work for studying the population genetic and genealogical impacts of dormancy.

92 Genealogical index of familiality analysis showed signif

93 Genealogical index of familiality results (P<0.001) for

94 Familiality was also evaluated with the genealogical index of familiality, which considers all r

95 velop a new transmission model in a Bayesian genealogical inference framework and demonstrate how to

96 Genealogical inference from genetic data is essential fo

97 We combined genealogical inference from genomic data with archaeolog

98 of clusters at all levels of similarity and genealogical inference of iterative-PopPUNK based on sim

99 article introduces a new general method for genealogical inference that samples independent genealog

100 In the case of genealogical inference using microsatellite loci, we use

101 Here we review the methods available for genealogical inference using Y-chromosome data.

102 t do not use an explicit population model in genealogical inference.

103 process can greatly increase the accuracy of genealogical inference.

104 d 121 Waorani elders of both sexes to obtain genealogical information and recollections of raids in w

105 resent a method that capitalizes on the rich genealogical information encoded in genomic tree sequenc

106 proposed gLike framework harnesses underused genealogical information to offer high sensitivity and a

107 and controls were identified through linked genealogical information.

108 g based on nationwide cancer data with valid genealogical information.

109 llows us to quantify the relative effects of genealogical inheritance and geographic proximity on the

110 ing mathematical expressions admit intuitive genealogical interpretations, which we utilize to introd

111 ill allow a much fuller picture of the close genealogical kinship of individuals across the world.

112 a demographic inference framework called the genealogical likelihood (gLike).

113 region of the Y chromosome (NRY), by using a genealogical likelihood-based approach.

114 cestries representing the main founding Arab genealogical lineages of Qahtanite (Peninsular Arabs) an

115 emarkably, the statistics for coalescence of genealogical lineages, derived from those deterministic

116 h are classic but little-used tools known as genealogical matrices.

117 path-based methods for efficiently computing genealogical measurements, such as inbreeding and kinshi

118 The same genealogical methods are used to find the probability of

119 Based on a genealogical model for admixture tracts, we develop an e

120 framework also incorporates a Wright-Fisher genealogical model of hosts, so that the dynamics of mic

121 ne of these two events is nonexistent in the genealogical model, the point estimation of the correspo

122 Gene genealogical models should describe the outcome of the p

123 Using simple genealogical models, we show that genetic distinctivenes

124 of a spatial population from a sample using genealogical models.

125 od of 20 years at one hospital combined with genealogical, neuropsychological, neurophysiological, ne

126 al ancestor has a physical history but not a genealogical one.

127 theory that considers multiple, sex-defined genealogical pathways through sexual organismal pedigree

128 mus, G. pennsylvanicus, and G. ovisopis, and genealogical patterns suggest that successive speciation

129 ions of the genome will display nonexclusive genealogical patterns.

130 A genealogical perspective on Hill-Robertson interference

131 evertheless infer the historical timings and genealogical placements of events of concerted change fr

132 Our genealogical population model identified heritable pheno

133 underscores how the stochastic nature of the genealogical process can affect inference from a single

134 A simple genealogical process is found for samples from a metapop

135 ge to cross the habitat range, the long-term genealogical process is reasonably well described by Kin

136 quentially Markov coalescent is a simplified genealogical process that aims to capture the essential

137 demonstrated that inference methods based on genealogical processes with recombination can uncover pa

138 The genealogical properties of a small population with conti

139 -Fisher (DTWF) model and compare several key genealogical quantities of interest with the coalescent

140 Genealogical reconstruction is fundamental to many of th

141 By using genealogical reconstruction, we investigated gene flow a

142 ry biology, forensics, medical genetics, and genealogical reconstruction.

143 s obtained from the Utah Medical Examiner to genealogical records and medical records data available

144 Genealogical records extending back five generations rev

145 ere then mapped to pedigrees using extensive genealogical records from the Utah Population Database t

146 lite based genetic inferences with long-term genealogical records to measure relatedness between coal

147 terites, a founder population with extensive genealogical records.

148 terns of diagnoses in extended, age-censored genealogical records.

149 clusters using a database of over 20 million genealogical records.

150 irs were obtained from the national twin and genealogical registers.

151 The growth in genealogical registries may contribute to loss of privac

152 find enrichments for migration, genetic, and genealogical relatedness patterns within river networks

153 Studies of spatial and genealogical relatedness reveal the self-organized spati

154 ntity states of two individuals with a given genealogical relationship are specified in terms of the

155 y highlight the conclusion that the power of genealogical relationship inferences can be enhanced eno

156 Here, we describe the variation in genealogical relationships across the genome among three

157 A low correlation between size variation and genealogical relationships among alleles suggests that a

158 The genealogical relationships among and origins of these br

159 hips among alleles in the LDGM correspond to genealogical relationships among haplotypes.

160 To elucidate the genealogical relationships among microsatellite alleles,

161 and Wakeley, who described the backward-time genealogical relationships among sampled individuals, as

162 n, (2) generates unprecedented resolution of genealogical relationships among tested individuals, and

163 n substructuring affect the geographical and genealogical relationships among these alleles.

164 d between individual genomes and to quantify genealogical relationships at different points in the pa

165 bination graphs (ARGs) summarize the complex genealogical relationships between individuals represent

166 edigree information, PADRE can even identify genealogical relationships between individuals who are g

167 Accurate inference of genealogical relationships between pairs of individuals

168 el of recombination compatible with observed genealogical relationships in sequence data from nine nu

169 Contrasting genealogical relationships in sexually isolated pheromon

170 ed phylogeographic analyses that incorporate genealogical relationships of alleles offer the exciting

171 nt difficulties due to the complexity of the genealogical relationships of genes and past migrations

172 In a finite population, the genealogical relationships of individuals can create sta

173 tion of RAD-Seq data in phylogeography means genealogical relationships previously evaluated using re

174 umber of mutations while partially resolving genealogical relationships when necessary.

175 ethods were used to infer genetic diversity, genealogical relationships, structure, gene flow barrier

176 s) from E.coli MG1655 among strains of known genealogical relationships.

177 lives, they will tend to interact with their genealogical relatives, which may give kin-selected bene

178 n type, resulting in cooperation between non-genealogical relatives.

179 s study opens the possibility for broadening genealogical research, even when only minor amounts of a

180 conservation genetics, forensic science, and genealogical research.

181 We primarily used a unique Utah genealogical resource to identify independent melanoma p

182 on (RaPID) query, is introduced to make fast genealogical search possible.

183 ng at any location in a panel, while in real genealogical search scenarios, multiple 'good enough' ma

184 e rapid growth of the genetic database size, genealogical search, a process of inferring familial rel

185 For genetic genealogical search, PBWT-based methods have optimized t

186 is an increasing need for conducting genetic genealogical searches efficiently.

187 In a genealogical showcase, we distinguished the patrilines o

188 We explored the genealogical signature of population dynamics detected f

189 election on long timescales, we identify new genealogical signatures that challenge standard populati

190 between evolutionary and demographic forces, genealogical structure and the resulting patterns of gen

191 mathematical analysis that describes how the genealogical structure at a neutral locus linked to the

192 enotypes of a collection of cells with known genealogical structure contains information on phenotypi

193 ty, patterns of molecular evolution, and the genealogical structure of alleles from L. parishii to a

194 The genealogical structure of neither gene departed from neu

195 selection has significantly distorted human genealogical structure on both broad and fine scales and

196 uch as population bottlenecks, can influence genealogical structure.

197 Genealogical studies demonstrated that the SSc cases wer

198 Genealogical studies place the birth of this ancestor >2

199 distinct E6-E7 haplotypes using codon-based genealogical techniques.

200 longifolia S alleles were used to divide the genealogical time into the within-clade and the between-

201 rst detailed for the S locus and analyzed in genealogical time scales.

202 tive cells did not carry a stable organismal genealogical trace.

203 ner population, consistent with our previous genealogical tracing studies.

204 atial and temporal dynamics of strains using genealogical tracing.

205 we present here use either the height of the genealogical tree (TMRCA) or the total branch length, re

206 proach accumulates sample weights within the genealogical tree at each position on the genome, which

207 uding the topology and branch lengths of the genealogical tree at each sequence site, and the times a

208 We then constructed a genealogical tree from the sequences of mutants taken at

209 ing that observed phenotypic dynamics on the genealogical tree is approximately conformal--a symmetry

210 Genealogical tree modeling is essential for estimating e

211 ical framework for dynamic adjustment of the genealogical tree of the NDs with the appearance of new

212 ne ND, motivated us to propose a model for a genealogical tree of the NDs.

213 se that have not, providing a glimpse of the genealogical tree relating the genomes to each other at

214 tes and measure how this variability affects genealogical tree structure, and thus genetic diversity.

215 , we use a model of phenotypic dynamics on a genealogical tree to define an inference method that all

216 e relationships among all lineages in a gene-genealogical tree with all possible trajectories of popu

217 By constructing a partially resolved genealogical tree with respect to these clusters, users

218 es across the branches of the Y chromosome's genealogical tree, we determined that this deletion aros

219 etailed relationships in a robust, worldwide genealogical tree.

220 ruction and exploitation of a patrilineal (Y-genealogical) tree based on several hundred single-nucle

221 of an MCMC method that generates samples of genealogical trees (from the posterior distribution for

222 phs (ARGs) encode the ensemble of correlated genealogical trees arising from recombination in a compa

223 e statistics' relationship to the underlying genealogical trees concrete and explicit), as well as th

224 that the branching patterns of reconstructed genealogical trees contains information about the relati

225 arge percentage of the clonal submembers and genealogical trees could be identified.

226 ise relatedness between individuals based on genealogical trees encoded in the ancestral recombinatio

227 genetic variation and is encoded in the gene-genealogical trees of the sampled haplotypes.

228 concentration and analyzed cell fate within genealogical trees statistically.

229 ikelihood estimation of coalescence times in genealogical trees, based on population genetics data.

230 udying the fundamental scaling properties of genealogical trees.

231 imately rely on the information contained in genealogical trees.

232 ncy spectrum on the topological structure of genealogical trees.

233 e imperiled populations represented by these genealogical units remains critical.

234 lective forces shape patterns of genetic and genealogical variation is unknown in many species.

235 testing, PRNP microsatellite haplotyping and genealogical work confirm no cryptic close family relati

236 Genealogical work with the large family originally repor