ライフサイエンスコーパス: generalizable

1 re needed to determine if those findings are generalizable.

2 suggesting that this new mechanism might be generalizable.

3 protein photoactivity, and are therefore not generalizable.

4 b, indicating that this mechanism is broadly generalizable.

5 however, it is unclear if these results are generalizable.

6 to establish that the approach is simple and generalizable.

7 cific, the approach and overall insights are generalizable.

8 lso making idiographic analyses scalable and generalizable.

9 training programs, but these are not easily generalizable.

10 g limitations, and a culture that avoids the generalizable.

11 reactivity of their targets and thus are not generalizable.

12 eto acids in aqueous solution are robust and generalizable across alkyl chain lengths.

13 disease-specific, and therefore, not easily generalizable across different neuropathologies or infla

14 tidepressant sertraline (versus placebo) and generalizable across different study sites and EEG equip

15 ormance from seasonal climatic variables was generalizable across growing seasons.

16 rturbed in tumors, the results are often not generalizable across independent datasets due to the pre

17 t the possibility for a synthetic oscillator generalizable across many organisms and readily linkable

18 as studied as a test-case, but the method is generalizable across oxidoreductase enzymes that rely on

19 ith cross-validation yielded a factorization generalizable across populations and medical systems.

20 determine if these findings were externally generalizable across practice settings.

21 ortantly, critical weights may or may not be generalizable across species.

22 individual differences in anatomy or are not generalizable across target sites.

23 rmine the degree to which these findings are generalizable across the tundra biome, our results indic

24 Unexpectedly, we uncover a potentially generalizable activation site that mediates drug resista

25 This approach is generalizable and can be applied to many multicomponent

26 The assay design is generalizable and can be readily modified to monitor vir

27 Our method is generalizable and can benefit large-scale human phenomic

28 we demonstrate that our selection method is generalizable and characterizes additional PV-specific e

29 a total of 56 datasets, we show that SAM is generalizable and consistently outperforms other methods

30 e likelihood that the study results are more generalizable and facilitate evaluation of the utility o

31 ved in homogeneous populations may be poorly generalizable and have the potential to reflect, perpetu

32 Our analysis pipeline is highly generalizable and is a useful alternative to the time co

33 These results illustrate generalizable and severe issues with fossil interpretati

34 timate goal of evidence-based, reproducible, generalizable, and broadly accepted results that will im

35 analysis, it needs to be economical, simple, generalizable, and free from tedious workflows.

36 The model is testable and generalizable, and helps to explain the counterintuitive

37 n-making algorithm that is physics-agnostic, generalizable, and operates in an abstract multi-dimensi

38 tered, quality improvement program is novel, generalizable, and practice changing.

39 work from which this classifier was built is generalizable, and represents a powerful, automated pipe

40 y demonstrates a conceptually novel, simple, generalizable, and scalable mouse genetic solution to sp

41 erty data are the most accurate, robust, and generalizable, and that property-based models can be tra

42 Our method represents a generalizable approach and provides a rich resource for

43 The generalizable approach developed here for the stabilizat

44 Altogether, SNP-7/8a is a generalizable approach for codelivering peptide antigens

45 e structural collapse represents a novel and generalizable approach for drug delivery of poorly solub

46 ntibiotic resistance in N. gonorrhoeae and a generalizable approach for epistatic genome-wide associa

47 ding of mast cell signaling and represents a generalizable approach for investigating the dynamics of

48 Alzheimer's disease diagnosis, as well as a generalizable approach for linking deep learning to path

49 Here, we present a generalizable approach for masking the binding domains o

50 Our generalizable approach should also provide a mechanistic

51 with studies on fluorination, demonstrates a generalizable approach to create new polymers with flexi

52 We show that CIRTS is a simple and generalizable approach to deliver a range of effector pr

53 These results indicate a generalizable approach to discover protein complex featu

54 A generalizable approach to modify their surfaces would al

55 cross Earth's biomes, an efficient, globally generalizable approach to predict LMA is still lacking.

56 -specific therapeutic target and establish a generalizable approach to rapidly identify novel therape

57 Collectively, this work provides a generalizable approach to understanding the logic of mol

58 Our highly generalizable approach, and the common set of features,

59 While a generalizable approach, predicting bacterial fitness ind

60 Availability of fully generalizable approaches for the systematic and efficien

61 We outline emerging mechanistic concepts and generalizable approaches to bridge the gap between micro

62 ycle for microbiome engineering, focusing on generalizable approaches, including top-down and bottom-

63 The approach presented is generalizable as it allows rapid construction of efficie

64 However, here I examine several generalizable aspects and research priorities.

65 emonstrating that it is a robust, valid, and generalizable asthma predictive tool.

66 of biomarkers for HIV persistence may not be generalizable between blood and other tissues.

67 We generate evidence that is generalizable beyond a particular contract scheme, crop,

68 ocalization with Aberrant Polypeptides), was generalizable beyond the ES7L mutation, as wild-type rib

69 ance of these findings, and whether they are generalizable beyond this study population, require furt

70 soils, it is still unclear whether there are generalizable biological or ecological processes that co

71 lities, models learn strongly associated and generalizable biological representations including sex,

72 We therefore developed a generalizable, but straightforward computational method

73 hope that this contribution highlighting the generalizable components of QSAR modeling will serve to

74 cribe a single-center approach to creating a generalizable, comprehensive, and graduated set of recom

75 A reliable and generalizable computational approach for modeling TICT f

76 Here, we describe a generalizable computational strategy for designing senso

77 These results support the emerging view that generalizable control states can become associated with

78 ver, despite intense research, we still lack generalizable, cross-scale indicators of mortality risk.

79 (LN) metastasis in thin melanoma in a large, generalizable data set and to evaluate the association b

80 Here we have developed a generalizable, data-driven solution to this challenge us

81 cer who are clinically node negative using a generalizable dataset.

82 Our generalizable de novo ligand binding site design method

83 To achieve generalizable deep learning models large amounts of data

84 We establish a generalizable definition for high occupancy target (HOT)

85 sation and the efferent arm of action - as a generalizable definition.

86 In addition to constituting the first generalizable demonstration of this relationship, our fi

87 rs and mechanisms of contact behavior into a generalizable disease modeling framework.

88 aph auto-encoder learns more informative and generalizable disease representations.

89 Hormesis is a generalizable dose-response relationship characterized b

90 anscriptomic study is often unstable and not generalizable due to cohort bias and limited sample size

91 ic study, however, is often unstable and not generalizable due to cohort bias, biological variation a

92 However, the generalizable effects of antibiotics on and the contribu

93 mmatory bowel disease (IBD), but determining generalizable effects of microbiota on IBD etiology requ

94 scaffold and our synthetic system are highly generalizable, enabling fabrication of a wide array of u

95 s, lifestyle, and/or genetics are robust and generalizable enough to be detected within a general pop

96 ed machine learning to identify a stable and generalizable factorization of the Positive and Negative

97 To ensure that the model learned generalizable features, it was further evaluated on two

98 d new examples that allow the description of generalizable features.

99 Generalizable FIs should be considered a standard approa

100 This new approach is generalizable for controlling BODIPY localization and wa

101 This approach should be generalizable for designing high-performance dielectrics

102 We believe our approach is generalizable for DNA aptamers regardless of sequence, s

103 etermined, demonstrating an approach that is generalizable for other interacting proteins.

104 This approach is generalizable for variant interpretation in many other c

105 We suggest that TransComp-R is a generalizable framework for addressing species, molecula

106 distinct South Asian studies, and provides a generalizable framework for ancestry-specific GPS assess

107 This work establishes a generalizable framework for finding resilience variants

108 n over hydrolysis, and provide a potentially generalizable framework for the rational creation of Alf

109 AZPs were leveraged within a generalizable framework to design conditional cancer dia

110 limate change [10], our synthesis provides a generalizable framework to understand how animal movemen

111 However, there are no simple and generalizable genetic methods to study neuronal or glial

112 Building on this inspiration, we describe a generalizable gram-scale method to assemble nanoparticle

113 (male) = 39, n(female) = 10), they represent generalizable ground-truths.

114 Here, we develop a generalizable host-gene-expression-based classifier for

115 ointestinal tract, whereas ILCregs are not a generalizable immune cell population in mice.

116 for convergence of findings, as well as some generalizable insights.

117 temperature annealing provides a potentially generalizable kinetic pathway to metastable variants of

118 alized on this high sensitivity to develop a generalizable kinetics-based approach, which provides re

119 ssemination and implementation science seeks generalizable knowledge about closing the gap between cl

120 Here, we present a generalizable machine learning workflow for identifying

121 Our annotation is fast, flexible and generalizable, making it possible for any variant file t

122 ate connectivity can be leveraged to produce generalizable markers of neurocognitive functioning.

123 This work introduces a generalizable mass balance model for estimating TE mass

124 Immediate, objective and culturally generalizable measures accessible upon clinical presenta

125 We demonstrate that this represents a generalizable mechanism by finding that a L. monocytogen

126 We postulate that there is a generalizable mechanism for selection against deleteriou

127 direct current stimulation (tDCS) suggests a generalizable mechanism of action.

128 stems of these model organisms may highlight generalizable mechanisms that microbiome dysbioses have

129 Subsequently, we build a generalizable method around the observation that global

130 ic elastomers has not been possible since no generalizable method for changing their Gaussian curvatu

131 This pY-TRAP approach serves as a generalizable method for engineering sequence-specific A

132 ed transcriptional reporters, we establish a generalizable method for exploring pharmacogenomics, str

133 A generalizable method for optical control of kinases woul

134 Our strategy provides an off-the-shelf and generalizable method for protecting DNs in vivo.

135 Here, we describe knockoff, a generalizable method for the druggable control of membra

136 enzymatic activities by chemical probes as a generalizable method for the phenotyping of bacterial ce

137 Here, we report a generalizable method of delivering proteins and ribonucl

138 Here, we present scPred, a new generalizable method that is able to provide highly accu

139 We have developed PESCA, a scalable and generalizable method that leverages ATAC- and single-cel

140 Here, we describe a generalizable method that utilizes exonuclease III and e

141 In sum, we present a generalizable method to screen for novel synergistic com

142 get occupancy in cultured cells, emphasizing generalizable methodologies able to deliver analytical p

143 Here, we report a generalizable methodology that allows engineering of mod

144 Until recently, there were no generalizable methods for assessing the effects of post-

145 receptor-specific interactomes and suggest a generalizable model for cue-selective control of the loc

146 s of small, community-based reserves offer a generalizable model for protecting biodiversity and augm

147 This work gives a generalizable model for the mechanism of iron porphyrin-

148 al motifs, leading to the perspective that a generalizable model of RNA folding may be developed from

149 e these propositions, we present a novel and generalizable model of statutory materials as multidimen

150 Instead, it directly learns generalizable model parameters characterizing the networ

151 The final result should be a generalizable model that takes brain connectivity data a

152 The lack of sizable datasets and generalizable modeling techniques that can fully represe

153 n strategies to facilitate more reliable and generalizable models for future clinical practice.

154 main findings were i) we were able to build generalizable models with clinically relevant accuracy (

155 Here, using simple and generalizable models, we show that even such small step-

156 ables and locations could help in developing generalizable models.

157 A generalizable multiobjective least-cost path model is fi

158 Our goal was to develop generalizable multivariate models that integrate high-di

159 dic detection of conformational changes is a generalizable, non-destructive technique, making it attr

160 Built on a generalizable ODAE design pattern and extending the OAE

161 s requires flexible representations that are generalizable over particularities of the current enviro

162 d vulvar pressure) to establish and validate generalizable pain representations.

163 However, studies of large, broadly generalizable patient populations are lacking, and the e

164 ther such losses are modulated by learning a generalizable pattern.

165 at are also present in ARDS, suggesting that generalizable patterns exist in diverse presentations of

166 onments diverge in their results, showing no generalizable patterns linking habitat and dietary degra

167 s in its highly accurate, interpretable, and generalizable performance for enhanced clinical decision

168 ross-validation prevents them from achieving generalizable performance on drug pairs where neither dr

169 ransmission, rather than acidification, is a generalizable phenomenon across conventional neuronal sy

170 iatric disease risk constitute a potentially generalizable phenomenon occurring more widely in comple

171 This study provides a generalizable pipeline for whole mitochondrial genome se

172 Collectively, we demonstrate a generalizable pipeline that can be applied to other prob

173 coded by the human microbiome and provides a generalizable platform for discovering molecular mediato

174 Here, we report a generalizable platform that provided the first synthetic

175 Here, we describe a generalizable platform to create dual-FP biosensors with

176 as designed to replicate these findings in a generalizable population of patients with migraine, incl

177 Our model makes generalizable predictions about the existence of asymmet

178 is meta-analysis firmly establishes globally generalizable, predictive taxonomic and functional micro

179 ial steps in the GTPase pathway represents a generalizable principle in GTPase signaling and explains

180 Copy number modulation is a generalizable principle that adds a layer of control to

181 nterconnected in complex ways, and for which generalizable principles of organization remain mostly u

182 This generalizable printing approach may be used towards the

183 These data provide generalizable proof-of-principle for this approach, and

184 t this function of s(2)C at position 32 is a generalizable property.

185 rdental cleaning and oral health in a large, generalizable prospective cohort of adults in the United

186 could be strengthened with access to broadly generalizable prospective samples; therefore, we recomme

187 enetic selection as a useful and potentially generalizable protein engineering tool for studying phos

188 This generalizable protocol allows determination of the accur

189 Serostudies are needed to answer generalizable questions on disease risk.

190 roviding additional support that AI-TAC is a generalizable regulatory sequence decoder.

191 A generalizable relationship science requires research tha

192 mptoms was identified as the most stable and generalizable representation of psychopathology.

193 This experience has illuminated some generalizable requirements for CAR T cell efficacy as we

194 d OCTA studies in this population and expect generalizable results.

195 ts than previously appreciated, suggesting a generalizable role for this cortical layer in influencin

196 irectly to film thickness, offering a novel, generalizable route to brookite growth that does not rel

197 ows synthetic DNA sponges offer a simple yet generalizable route to systematically engineer the perfo

198 etic route, well-suited to SAR, represents a generalizable route toward all manner of analogues, incl

199 s have so far been evaluated in a population-generalizable sample.

200 ggests that the decoration of this series of generalizable scaffolds can conveniently reach the bindi

201 These provide the foundation for designing generalizable scaffolds that can directly mimic the bind

202 can countries, is necessary to determine how generalizable signature performance is.

203 Our data-driven approach may constitute a generalizable solution for connectome-based diagnosis.

204 frontoparietal cortex encodes tasks using a generalizable spatial pattern in switch and repeat trial

205 m macroecology and meta-analysis to identify generalizable spatial patterns.

206 gic status in a blinded fashion to develop a generalizable statistical model for comparison to extrac

207 However, generalizable strategies that accomplish this with high

208 ptide epitope fusions represent a facile and generalizable strategy for enhancing the T-cell response

209 Here, we present and evaluate a generalizable strategy for identifying drug dosing sched

210 ggest that this link could be exploited as a generalizable strategy for identifying the Treg cell ant

211 Our approach offers a highly generalizable strategy for integrating pH-responsiveness

212 een 2D and 3D cancer models, and establish a generalizable strategy for performing CRISPR screens in

213 C-mediated matrix remodelling proved to be a generalizable strategy for stemness maintenance in 3D.

214 This approach represents a generalizable strategy for the safe and consistent deliv

215 urface becomes more hydrophilic, proposing a generalizable strategy to control wettability and an elu

216 We expect the island formation as a generalizable strategy to make patchy NPs of various sha

217 We present a generalizable strategy to preserve and constrain genetic

218 Application of this generalizable strategy will facilitate broad nanoparticl

219 sensing materials, suggesting that this is a generalizable synthetic strategy for preparing highly ro

220 G-baToN is a generalizable system that enables physical contact-based

221 th generic language to be more important and generalizable than findings expressed with nongeneric la

222 ing on the ocean, in which N cycling is more generalizable than in terrestrial systems, which are mor

223 Their predictions are more generalizable than the specific mappings in conceptual m

224 Here, we explore how generalizable this phenomenon is by giving H. trimaculat

225 antigen; therefore, this approach should be generalizable to a wide array of bacteria and find appli

226 This 1D superlattice approach is generalizable to a wide range of layered materials.

227 The model is further generalizable to account for dynamics of contrast-depend

228 l and the nucleus, a strategy that should be generalizable to all basophilic kinases.

229 This method is generalizable to all complex traits with relevant annota

230 Thus, this guide is intended to be generalizable to all research scenarios and projects in

231 is physicochemical trapping method, which is generalizable to analytes beyond the scope of this work,

232 The approach is generalizable to any annotations that have been made to

233 Importantly, this assembly strategy is generalizable to any application that requires nanopore

234 ggests that previously reported findings are generalizable to Asian patients.

235 lament density, suggesting this model may be generalizable to bacteria that elongate via the Rod comp

236 her information derived from social media is generalizable to broader populations, especially middle-

237 Our approach is generalizable to designing monotherapy and multi therapy

238 easible in 3D whole-body MRI datasets and is generalizable to different epidemiologic cohort studies

239 LAmbDA is model- and dataset-independent and generalizable to diverse data types representing an adva

240 expression trends during differentiation, is generalizable to diverse tissue types, and is well-suite

241 and our procedures to define invariants are generalizable to higher coordination number and dimensio

242 tantly, this reversible covalent strategy is generalizable to improve other PROTACs, opening a path t

243 The results may not be generalizable to institutions without academic bioethics

244 rs, and the observed associations may not be generalizable to less severe and subclinical cases of mi

245 However, these findings may not be generalizable to low-income settings.

246 of preparation of corrole/protein NPs may be generalizable to many bioactive hydrophobic molecules to

247 We believe the technique is generalizable to many colorimetric formulations, and as

248 The methods described are completely generalizable to many nucleic acid biomarkers, and could

249 Our approach is generalizable to most identity providers and cloud compu

250 was to determine whether these patterns were generalizable to multiple amphibian species under more n

251 ading batch-effect correction techniques and generalizable to multiple experimental designs.

252 on data in laboratory grade water may not be generalizable to MWW applications.

253 commercial medical insurance and may not be generalizable to older or uninsured populations.

254 The proposed checklist framework is generalizable to other areas of ecology, especially thos

255 e effect of L. reuteri on social behavior is generalizable to other ASD models and its mechanism(s) o

256 lations applies to gamma in V1 and is likely generalizable to other brain regions and rhythms.

257 ed role as a lipid-binding protein, possibly generalizable to other C1q/TNF-related proteins (CTRPs)

258 This effect is generalizable to other conditions of impaired fork rever

259 from RNA-Seq studies, this method is easily generalizable to other data modalities and analysis type

260 emented and to determine whether results are generalizable to other health care markets.

261 rPWR and rCST estimates are generalizable to other indexes of energy supply and neur

262 re cycling to "freeze" intermediates will be generalizable to other living polymerization techniques,

263 These mechanisms are generalizable to other metal-enriched QD surfaces that h

264 neurons, suggesting that DRG findings may be generalizable to other nervous system structures.

265 Moreover, we prove that such strategies are generalizable to other optical homo-dimerizers by demons

266 was limited to US veterans, which may not be generalizable to other populations, our results suggest

267 The presented structure-based approach is generalizable to other protease enzymes with known or mo

268 ns include that our conclusions might not be generalizable to other settings because our model descri

269 in a single clinical setting that may not be generalizable to other settings.

270 e availability, it is likely our results are generalizable to other situations, such as habitat resto

271 , it is uncertain whether these findings are generalizable to other states.

272 ow that compact electrotonic architecture is generalizable to other STG neuron types, and that these

273 ntary to existing genetics-based approaches, generalizable to other systems, and enabling for future

274 ted to a set of tasks; however, our model is generalizable to other systems.

275 ngle degree of freedom and control should be generalizable to other two-dimensional systems, which ma

276 SARS-CoV-2 vaccine development, which can be generalizable to other viruses.

277 e-modifying enzyme to stem cells that may be generalizable to other, difficult-to-transduce cell type

278 These findings may not be generalizable to PWID not enrolled in OAT programs.

279 eters for RNA duplexes in 20% PEG 200 may be generalizable to RNA and DNA duplexes in solutions with

280 The presented advances are likely generalizable to the creation of other types of sensors

281 Plant trait relationships are thus generalizable to the edge of global trait-space, informi

282 from single-center studies, which may not be generalizable to the international multicenter experienc

283 ondrial metabolites and serves as a strategy generalizable to the study of other mammalian organelles

284 The results may not be generalizable to vaccinations done in other types of hea

285 variability over periods of years may not be generalizable to variability over periods of days and ot

286 SupraCell formation is shown to be generalizable to wide classes of nanoparticles and vario

287 Here we describe FlpStop, a generalizable tool for conditional gene disruption and r

288 strategies, motivating the development of a generalizable tool for regulating multiple sets of genes

289 in vivo and in vitro provides a powerful and generalizable tool to probe the mechanisms by which H3 t

290 y through Recombinase Competition (SPARC), a generalizable toolkit that can express any effector in p

291 lectrochemical phase interrogation may prove generalizable toward subsecond measurements of molecular

292 If our findings are generalizable, TSD squamates, tuatara, and crocodilians

293 The paucity of generalizable typhoid epidemiological data in early intr

294 We develop a novel generalizable ultrasensitive amplicon barcoding approach

295 These analyses provide insights into the generalizable, underlying features of epitope-specific r

296 However, we currently lack a generalizable understanding of how these soil communitie

297 A comprehensive, generalizable understanding of outcomes after pediatric

298 To show that OncoSig is generalizable, we first inferred SigMaps for the ten mos

299 We developed a generalizable yeast-based platform for directed evolutio

300 Our "isomeric tuning" approach is generalizable, yielding a far-red targetable indicator t