ライフサイエンスコーパス: generate

1 nts of DNA sequence and other omics data are generated.

2 ation-deficient p53-S180A knock-in mice were generated.

3 c potency but retained T-cell activation was generated.

4 and TET3) oxidize 5-methylcytosine (5mC) and generate 5-hydroxymethylcytosine (5hmC) marks on the gen

5 future catch by at least 20% via spillover, generating 9 to 12 million metric tons more food annuall

6 nearby field laboratory and used the data to generate a chromosome-scale draft genome sequence.

7 onsider the similarities between features to generate a concise feature map in the form of a two-dime

8 synapses can be tuned from weak to strong to generate a family of models that spans a continuum from

9 with RHD3 to move the ER on microtubules to generate a fine ER network.

10 Here we generate a living organoid biobank from patients with lo

11 In this issue of the JCI, Auguste et al. generate a mouse model of DCM in which they delete Lmna

12 polymer was utilized for modifying a GCE to generate a new electrochemical sensor.

13 dltB(r)) strain demonstrated its capacity to generate a similar inflammatory response to a wild-type

14 a ice, ice shelf and glacier retreat) losses generate a valuable negative feedback on climate change.

15 iral and Modified Vaccinia Ankara vectors to generate a viral-vectored vaccine, referred to as Nous-2

16 compatibilities accumulating with divergence generate a weak barrier to gene flow for long periods of

17 We generated a doxycycline-inducible adipose tissue-specifi

18 rating these BMP15 residues into latent GDF9 generated a highly potent growth factor, called hereafte

19 IF11-associated retinal vascular disease, we generated a Kif11 conditional knockout (CKO) mouse and i

20 Herein, we generated a mouse model that allow for activation of NF-

21 To highlight our technique, we generated a multi-responsive hydrogel that, at one tempe

22 This alteration generated a nonfunctional CD56(bright) NK cell subset ch

23 senchymal plasticity in PDAC progression, we generated a PDAC mouse model in which CAF plasticity is

24 arily interrupted a cold and dry climate and generated a warm and wet period.

25 e consumption of O(2) with a diffusion model generates a broad range of microsite concentrations of O

26 ampling with unsigned chemical shift changes generates a diversity of structures that are sufficient

27 This mechanism generates a metabolic homeostatic circuit that protects

28 ish the conditions in which indirect defence generates a plant-natural enemy mutualism.

29 nt (top2-F1025Y,R1128G) the product of which generates a stabilized cleavage intermediate in vitro.

30 de chain), TmAAE13 as the best candidate for generating a CoA ester of tiglic acid (Taxol B side chai

31 l involvement in OSCC, with driver mutations generating a conducive microenvironment on the epithelia

32 After generating a strain that expresses green fluorescent pro

33 y any (bio)organic molecule or metal cation, generating a wide range of materials with tailored prope

34 ts of biological data continue to be rapidly generated, a major focus of bioinformatics research has

35 mages were acquired to assess their contrast-generating ability.

36 gth or body mass index-for-age z scores were generated according to the World Health Organization sta

37 e (ACLY) enzyme cleaves cytosolic citrate to generate acetyl-CoA, and is upregulated after consumptio

38 key factor underlying adaptation is the self-generated activity that allows participants to learn new

39 rmacological profiles of at least two of the generated ADCs compare well with the profiles of the cor

40 d for high-dimensional propensity scores, to generate adjusted hazard ratios (aHR).

41 The peptide profile generated after in vitro and in vivo digestion showed cl

42 This would, in theory, generate aminyl and carboxylate radicals, with the latte

43 ns to Lgmn decreased the current required to generate an action potential through PAR(2) Inhibitors o

44 f two neural networks: (i) an autoencoder to generate an embedding that can reconstruct original meas

45 t coordinate cell fate and tissue shape will generate an integrated understanding of early embryogene

46 nation of MTP-PE and IFN-gamma on AML blasts generated an inflammatory cytokine profile and activated

47 We additionally generated an RFX6(HA) reporter allele by gene targeting

48 cell image from one of the stages, ImageAEOT generates an artificial lineage of this cell based on th

49 ely transposed during somatic embryogenesis, generating an average of 6.37 insertions per line in a p

50 ctron transfer (ET) from [4Fe-4S](+) to SAM, generating an R(3)S(0) radical that undergoes regioselec

51 Participants generated and matched elbow torques when the shoulder wa

52 We generated and subjected mice with EC-AGO1 deletion (EC-A

53 actor (FGF) signaling plays pivotal roles in generating and maintaining NPCs during kidney developmen

54 Generating and utilizing models that accurately predict

55 to its ability to remodel cardiac tissue and generate angiotensin II.

56 Here, we report a method to generate antibody-siRNA (1:2) conjugates (ARCs) that are

57 The key challenge in generating antibody-based inhibitors is the lack of fund

58 control immune responses in plant leaves and generated Arabidopsis transgenic plants.

59 ved current natural marine snow protocols to generate 'artificial' marine snow, into which bacteria c

60 LC(+mcra) can generate bioactive compounds in larger quantity includin

61 digestate is a waste diversion strategy that generates biogas and soil amendment products.

62 ctivate the T6SS even when the disruption is generated by aberrant cell envelope biogenesis.

63 ement of senescent taste cells with new ones generated by adult taste stem cells.

64 e results establish that silent synapses are generated by an astrocyte-mediated synaptogenic mechanis

65 e differential expression pattern categories generated by AW-Fisher can become intractable.

66 strate this technique by measuring tractions generated by both single human neutrophils and multicell

67 The liver imaging features generated by CNN may have the potential to predict liver

68 Single-subject atrophy maps were generated by comparing cortical thickness in patients wi

69 ikely that the most accurate picture will be generated by consolidating information relating to trans

70 Arachidonic acid epoxides generated by cytochrome P450 (CYP) enzymes have been lin

71 onas putida MET94 (PpDyP) and three variants generated by directed evolution (DE) are studied aiming

72 Cryo-EM data generated by electron tomography (ET) contains images fo

73 Macaque TSC lines were generated by isolating first and second trimester placen

74 A 3D model of MpBgl3 was generated by molecular modeling and used for the evaluat

75 is a low voltage-activated potassium current generated by neuronal Kv7 channels.

76 that the complexity of cortical circuits is generated by phylogenetically old interneuron types, com

77 This pathway activation reduces ROS generated by QR2 enzymatic activity, a process that alte

78 ensional atomic models from candidate graphs generated by RAG Sampler, and (c) RAG Designer: designs

79 he miRNA is expressed from an intron that is generated by RNA polymerase II transcribing the circular

80 A connectome from central macaque retina was generated by serial blockface scanning electron microsco

81 Epithelial structure is generated by the dynamic reorganization of cells in resp

82 azide with 2H-azirine-2-carbonyl chlorides, generated by the Fe(II)-catalyzed isomerization of 5-chl

83 We further demonstrate that the meshes generated by the Geometry-preserving Adaptive MeshER sof

84 the ensembles of bound peptide conformations generated by the programs MODELLER and Rosetta FlexPepDo

85 quencing data from tissue-specific mouse ECs generated by the Tabula Muris consortium.

86 rction, causes a decrease of the cGMP levels generated by these receptors and a change of subcellular

87 ied in human plasma samples with annotations generated by three similar tools, we found that Binner a

88 The hydrogen peroxide generated by XO catalysed oxidation of hypoxanthine, and

89 that large disease-linked and experimentally generated C-terminal truncated KCNQ3 mutants retain the

90 Following affinity capture, we generated calibration curves (five-parameter logistic fi

91 due to its broadband absorption and does not generate cellular stress.

92 oach adopted demonstrates its versatility in generating chemical diversity for allosteric targeting o

93 s within cap-snatched host transcripts could generate chimeric human-viral mRNAs with coding potentia

94 preserving their pluripotency and ability to generate chimeric mice.

95 We optimized a protocol to generate choroid plexus organoids from hiPSCs and showed

96 Ultimately, this generates chromosomal abnormalities and the release of n

97 Here, we set out to examine how song-generating circuits may be influenced early in song lear

98 activity may provide a general mechanism for generating coherent neuronal dynamics without the need f

99 These results suggest that IDS generates communicative expectations in infants.

100 s for pharmaceutical and device companies to generate comparative data on drugs and devices and assur

101 differential responses to regulatory inputs generate complex patterns of binary and graded cell fate

102 We generated conditional knockout mice in which brain AMPKa

103 present together with non-cooperative spike-generating conductances.

104 ies have focused on pernicious anaemia only, generating confusion between the two entities.

105 adducts were identified as the main type of generated conjugates.

106 geological repository in every nuclear waste-generating country, but carbonate rocks may serve as a p

107 th live typhoidal serovar, Salmonella Typhi, generates cross-reactive immune responses, which provide

108 e the structural basis of neutralization, we generated cryogenic electron microscopy reconstructions

109 Rather than generate data from a theoretical model, in this paper we

110 transcriptomics, proteomics and metabolomics generate data that relate more directly to the pathologi

111 ngle cells, multicellular organisms robustly generate different cell types from one zygote.

112 Univariable and multivariable analyses generated differing inference for 11/30 (30.67%) disorde

113 aterial also result in waste that is readily generated, dispersed, and fragmented in the environment.

114 where the first hematopoietic stem cells are generated during development, we performed genome-wide R

115 gamma-ketoalkenal phospholipids or by oxPLs generated during HDL oxidation in plasma by the physiolo

116 from decomposition of nitrosoperoxycarbonate generated during inflammation.

117 Treg cells can be generated during thymic development (called thymic Treg

118 e spindle is not simply a switch, but rather generates effector gradients where importins alpha and b

119 sequestered, H(2) and/or O(2) may be used to generate electric power via fuel cells or combustors, O(

120 remarkable Stokes shift of 15 000 cm(-1) to generate emission at 633 nm.

121 qcNIR allows 100% tumor margin assessment by generating en face images that correlate with histology

122 ouble membrane-bound cellular organelle that generates energy to maintain the homeostasis of cells.

123 pplication of an approach that automatically generates, evaluates, and proposes cyclizations utilizin

124 veloping human cerebral cortex necessary for generating expanded neuronal populations.

125 dification of development was fundamental in generating extant plant diversity.

126 ct, during the reduction of substrates, NQO2 generates fairly unstable intermediates that reoxidize i

127 Regional time-activity curves were generated for 14 regions of interest.

128 Three complementary regression models were generated for number of patients seen, number of service

129 t was trained on four different databases to generate four different models: (a) 375 neuroradiologist

130 function as catalytically active hexamers to generate free amino acids from human hemoglobin and are

131 F3 offspring were generated from each of these lineages and examined for o

132 (iPSC)-derived neuronal stem cell lines were generated from individuals with MDD.

133 elop a microfluidic chip formed by HGPS-SMCs generated from induced pluripotent stem cells (iPSCs), t

134 Furthermore, 19-CAR-ML NK cells generated from lymphoma patients exhibited improved resp

135 per Learner, and compared these with results generated from multivariable logistic regression.

136 um samples (n = 15), and using mAbs (n = 14) generated from peripheral B cells of two patients.

137 reover, in TPR-depleted cells reporter mRNAs generated from short transcripts accumulate in nuclear s

138 c deformation in comparison to their analogs generated from statistical copolymers.

139 ent permanent electrical dipole orientations generated from the Gd atom being trapped at two differen

140 spatial expression patterns of genes in data generated from various spatially resolved transcriptomic

141 CM stimuli rarely generated full IOG, but predominantly generated superimp

142 ese results demonstrate that the CRISPR-Cas9 generated Gaa(c.1826dupA) murine model recapitulates hyp

143 gy and Lkb1 in normal tissue homeostasis, we generated genetically engineered mouse models where we c

144 regarding the history of these movements, we generated genome-wide data for 11 ancient individuals fr

145 sted "the expensive germ line" hypothesis by generating germline-free zebrafish Danio rerio and testi

146 From raw grayscale data, we generated graphs encoding the 3-dimensional geometry of

147 of anterograde transneuronal spread of AAV1 generates great promise for its application as a unique

148 orm this metamaterial, and collectively they generate hard-to-attain broadband deep-subwavelength abs

149 functional group tolerance, and the in situ-generated HCN bypasses the use of an external cyanide so

150 gneto-patterned in hydrogels and cultured to generate heterogeneous tissues.

151 vercome the overexpression problem, and have generated high depth RNA-sequencing on FUS mutants in pa

152 essential for the activated methyl cycle and generates homocysteine for conversion to l-methionine.

153 We generated homogeneous populations of developing cINs fro

154 Their proof-of-principle for generating human tissue is demonstrated by 3D bioprintin

155 We propose that basin-impact-generated hurricane-force winds created sediment-laden a

156 show that mismatch between the nature of the generating (i.e. biological) process and the form of the

157 non-overlapping molecular compositions that generated identical odour percepts.

158 We generated immunodeficient Rat Rag-/- Gamma chain-/- huma

159 did not trigger the mechanisms necessary to generate immunological memory able to induce long-term p

160 tablished for Chinese cynomolgus macaques to generate in vitro MCM embryos.

161 Triplet syn-2-formyl-3-fluorophenylnitrene, generated in argon matrices by UV-irradiation of an azid

162 lly offset PV GPe and STN neuron activity is generated in part by elevated striatopallidal transmissi

163 In plants, NO is generated in pollen tubes (PTs) and affects intracellula

164 we found that in pig kidney, ATP was rapidly generated in presence of oxygen (100 kPa), which remaine

165 g unique cargos, including the GTPase Rab11, generated in Rab11-positive recycling endosomal MVBs.

166 he antimicrobial free nitrous acid, which is generated in situ from calcium nitrite that is added to

167 st, transmetallation of the Na- or K-enolate generated in situ, and subsequent reductive elimination.

168 turn synthesized from a precursor metabolite generated in the isoleucine catabolic pathway.

169 ites based on total RNA sequencing data sets generated in this study as well as those deposited in th

170 Collectively, the data generated in this study suggest a polygenic adaptation o

171 Trajectories generated in this way show good agreement with measured

172 We employ HIOs generated in this way to measure CFTR function using cys

173 We generated individualised risk tables for patients with c

174 Generating insulin-expressing cells in vitro is no excep

175 The results obtained from smog chamber-generated isoprene SOA and aqueous-phase laboratory expe

176 mbient fine aerosol (PM(2.5)) and laboratory-generated isoprene SOA.

177 visit the effects of open unc-64/syntaxin by generating knockin (KI) worms.

178 To this aim, we generated Langerin-specific and CD11c-specific knockout

179 The ability to generate large panels of peptides and subsequently large

180 tic coupling, in which an excitatory synapse generated large negative extracellular signals that nons

181 The early-generated, largely transient neurons of the subplate pla

182 the interneurons to the training odorants to generate learned olfactory behavior.

183 BSM strips overexpressing desmin or vimentin generated less force in response to KCl and carbachol re

184 roduct and synthetic chemistry approaches to generate libraries of compounds, with some ending as pro

185 but not exclusively) members of the pandemic generating lineage capable of causing the diarrhoeal dis

186 A4 controls the priming stroke of the motion-generating linker, which connects the dimerizing tail of

187 This strategy may be useful for generating live attenuated vaccine candidates that preve

188 described a strategy to rapidly identify and generate llama nanobodies (VHH) from naive and synthetic

189 tructures were low, suggesting that HFOs are generated locally within the LS GABAergic population.

190 nomers, we applied SD to the set of recently generated long accurate Pacific Biosciences HiFi reads.

191 ells provide B-cell help and are crucial for generating long-term humoral immunity.

192 The generated LyP-1-QU-NPs had a desirable diameter (203.2 n

193 fatty acids, including arachidonic acid, and generate lysophospholipids from phospholipids, including

194 o to a published cancer dataset and to newly generated matched scRNA-seq and exome-seq data from 32 h

195 mong progenitor cells with their capacity to generate mature cell types.

196 recursor miRNA by Dicer and other components generates mature miRNA.

197 Generated MDSCs displayed a glycolytic switch, which ren

198 on starts at gastrulation, when the epiblast generates mesoderm and endoderm germ layers through epit

199 ith the latter undergoing decarboxylation to generate methyl radicals.

200 determine if structure informs function, we generated mice with zG-specific expression of GCaMP3 and

201 gest that shockwaves produced by a blast can generate micron-sized bubbles in the tissue.

202 ing to their biocompatibility and ability to generate microscale force gradients.

203 is subject to methodological issues that can generate misleading results.

204 Additionally, this method generated monolayers with enhanced barrier integrity, so

205 but stimulates the dimeric paclitaxel (PTX) generating monomeric PTX.

206 Myosin II is the main force-generating motor during muscle contraction.

207 Results support the hypothesis that self-generated movements underlie adaptation to radical senso

208 In parallel, we generated multiple CRISPR knockouts of the fly rrp4 gene

209 for in-tip TIE, only 3.6 mL of residues was generated (n = 12) over 60-240 mL in reference methods (

210 connected via a pH sensitive imine bond, we generate nanoscopic polymersomes that are then modified

211 view underscores the myriad factors that can generate NCE contingencies while guiding how research mi

212 e into sites of spinal cord injury (SCI) and generate neuronal relays across lesions that can provide

213 are remarkably plastic, and that dynamic GNs generate new biosynthetic pathways in different Brassica

214 Unable to generate new enzyme paradigms and metabolic networks de

215 failure of MSC-based virotherapy as well as generate new hypotheses.

216 g cis- and trans-acting lncRNAs in vivo, and generating new developments in high-throughput screening

217 studies on the SAGA coactivator complex are generating new paradigms for how the components of these

218 pproximate optimization algorithm (QAOA), we generate nontrivial thermal quantum states of the transv

219 , we demonstrate that NADPH oxidase 2 (NOX2) generated oxidative injury causes upregulation of a cons

220 AON detects the coincidence of these inputs, generating patterns of activity reflective of episodic o

221 m memory of the membrane potential allows to generate persistent firing when clusters of cooperative

222 ta demonstrated that HT-DBP could be used to generate personalized pharmacotypes.

223 igh-throughput reaction discovery in flow to generate pharmaceutically relevant compound libraries.

224 Stochastic pulsing of gene expression can generate phenotypic diversity in a genetically identical

225 ate by either shifting a single parameter or generating "populations" of model parameters.

226 was identified as the source of the thrombin-generating potential underlying fibrin(ogen)-dependent b

227 lar plant database for the United States and generate predictive models of regional plant taxonomic a

228 anch of computer science and statistics that generates predictive or descriptive models by learning f

229 derived and compared different approaches to generating predictive polygenic risk scores (PRS) from g

230 The generated product water was characterized by an up to 5-

231 eveloping IONPs as T(1) contrast agents have generated promising results, but the complex, interrelat

232 rogress, we are still far from being able to generate PSC-derived cardiomyocytes with adult-like phen

233 tative abiotic proxy, glendonite calcite, to generate quantitative temperature estimates for northern

234 asically, the inherited ability of TiO(2) to generate reactive oxygen species is used as a strategy t

235 egulatory regions by specific demethylase(s) generates reactive oxygen species (ROS), which oxidize D

236 Proton flow through the F(o) motor generates rotation of the central stalk, inducing confor

237 This new in situ generated Ru complex, 4(2-), has been isolated and spect

238 Our findings may help efforts aimed at generating salt-tolerant crops.

239 To generate scMNase-seq libraries, single cells are isolate

240 We generated semiautomated and flexible ImageJ2/Fiji pipeli

241 s and are often incompatible with polymerase-generated sequences.

242 levels of complexity: a context-free grammar generating sequences following a mirror structure (e.g.,

243 , ABC | CBA) and a context-sensitive grammar generating sequences following a repeat structure (e.g.,

244 ntrations in Precambrian seawater would have generated serpentinites that produced up to two orders o

245 ptions, each with different probabilities of generating shocks, while also seeing the image of a soci

246 sional representational spaces these methods generate, simple prototype models can perform comparably

247 We analyzed previously generated single-cell RNA-sequencing (scRNA-seq) data of

248 Generating single-cell, multiparametric, longitudinal at

249 e at elevated temperature, which was used to generate six-membered phosphorus heterocycles via hetero

250 the relative tendency of each hemisphere at generating slow waves.

251 values and reveal the unique role of TSS in generating SOT.

252 ticulin, ERp57, and STIM1 activated SOCE and generated spontaneous cytosolic Ca2+ flows.

253 ocus can be epigenetically edited ex vivo to generate stable therapeutic iTregs.

254 graphy-tandem mass spectrometry with de novo-generated standards and an isotopic dilution strategy an

255 ied the STING-interacting domain of TRIF and generated STING-noninteracting mutants of human and mous

256 We show that 21-plex DiLeu tags generate strong reporter ions following HCD fragmentatio

257 ncreasingly important mode of migration that generates substantial remittance flows, but raises impor

258 ing on land consumes [Formula: see text] and generates sulfate that is carried to the ocean by rivers

259 rarely generated full IOG, but predominantly generated superimposition.

260 ssion can propagate within the BC network to generate synchronous inhibition of Purkinje cells, which

261 By using the MiCRM to generate synthetic data with different environmental and

262 eep convolutional neural networks (DCNNs) to generate synthetic MRI ventilation scans from free-breat

263 lude that while conjugation of long-chain Vi generates T-dependent antigens, the conjugates also reta

264 ytic reductive cleavage of the S-C5' bond to generate the 5'-dAdo. radical.

265 or reconstruction are those that are used to generate the acoustic speech signal.

266 nd model is trained on remaining lifespan to generate the AFRAID (Analysis of Frailty and Death) cloc

267 We were also able to generate the H(inact) state anaerobically via both chemi

268 This protocol takes 2-3 weeks to generate the labeling cells and 1-2 weeks to test their

269 Finally, we generate the most complex experimental lineage tracing d

270 Herein, we have generated the global histone mark based epigenomic and t

271 before cooking proved to be the method that generates the greatest reduction.

272 tion requires a UDP-GlcNAc C4-epimerase that generates the UDP-GalNAc precursors required by the Pel

273 ial fatty acid biosynthesis, is important in generating the fatty acid precursor of lipoic acid biosy

274 neurons, including their molecular clock, in generating the mammalian locomotor activity (LMA) circad

275 However, generating the required technologies and infrastructure

276 ytidine and uridine), and we show that, once generated, the pyrimidines persist throughout the synthe

277 dney biopsy, blood and urine samples used to generate these different types of molecular data are fre

278 We show that mechanochemically generated thiol-terminated polymers undergo a Michael-ty

279 The (FSF)TGFbeta(CA) allele was created to generate this model, and functionally validated by in vi

280 ) microendoscopes using aspheric microlenses generated through 3D-microprinting.

281 es, NMe), the radical-anion salt K[7(*)] was generated through chemical reduction with K metal and ch

282 rm mode, the most common fish swimming mode, generate thrust on their anterior bodies using leading-e

283 as evaluated as a time dependent variable by generating time-dependent Cox models; HRs at an ELF thre

284 Consequently, ions generate transient electrical currents first discovered

285 ody of evidence that AAA+ molecular machines generate translocating forces by a common mechanism.

286 red photolysis of silver trifluoroacetate to generate trifluoromethyl radicals, confined only to the

287 vating ESR1 mutation, Y537S-ER, were used to generate tumor xenografts in ovariectomized female immun

288 d Monte Carlo and optimization algorithms to generate two different intensity-modulation patterns, na

289 vances our knowledge of how ganglion neurons generate uncharacteristic electrical impulses due to abn

290 al via beta-scission from a tertiary radical generated upon chlorine-mediated hydrogen atom transfer.

291 ue of model-guided design as an approach for generating useful DNA parts.

292 Both signals are generated using an elastic spring system (ESS), which in

293 single nucleotide polymorphism (SNP) markers generated using the 2bRAD approach to assess fine-scale

294 amework will improve the quality of evidence generated utilizing these models.

295 irus (HBV) and human cytomegalovirus (HCMV), generated via a similar mechanism exploiting the TENT4-Z

296 porcine epidemic diarrhea virus (icPEDV), we generated viruses with inactive versions of interferon a

297 gen (H(2)) is a potent reductant that can be generated when water interacts with reactive components

298 able data from the Allen Brain Institute, we generated whole brain and regional signatures of AMPAR s

299 high-throughput sequencing of rpoB amplicons generated with a Streptomyces specific primer set.

300 in the diameters of each entoptic phenomenon generated with depolarized and linearly polarized light