ライフサイエンスコーパス: genitalia

1 ly a few traits (e.g., pigmentation and male genitalia).

2 romote the evolution of both male and female genitalia.

3 ulinemia and/or refractory warts of skin and genitalia.

4 rdered steroidogenesis, exhibiting ambiguous genitalia.

5 congenital structural abnormality of female genitalia.

6 The authors then examined the adolescents' genitalia.

7 matic hernia, renal hypoplasia and ambiguous genitalia.

8 of XX Ods/+ mice that develop with ambiguous genitalia.

9 and differentiate into parts of the internal genitalia.

10 tions disturbing development of the skin and genitalia.

11 strong contrast enhancement of the external genitalia.

12 or roles in the development of the limbs and genitalia.

13 sex-specific roles in the development of the genitalia.

14 , and differentiation of the male and female genitalia.

15 evelopment of the male internal and external genitalia.

16 and cosmetic appearance of the reconstructed genitalia.

17 evident in spleen, the facial image and male genitalia.

18 lipomas, and pigmentation spots of the male genitalia.

19 t that males and females had female external genitalia.

20 he normal development of gonads and external genitalia.

21 s of primordia for the hindlimb and external genitalia.

22 pment and differentiation of testes and male genitalia.

23 highly enriched AR-regulated pathway in the genitalia.

24 ases associated with defects in the external genitalia.

25 he penetration mechanics of elongated beetle genitalia.

26 acterized by neurodegeneration and ambiguous genitalia.

27 nd characterised by morphologically distinct genitalia.

28 d clitoral hypertrophy or ambiguous external genitalia.

29 cific genes underlying the evolution of male genitalia.

30 in genetic females with nearly complete male genitalia.

31 in cis-regulatory activity between limbs and genitalia.

32 of enhancer activity in developing limbs and genitalia.

33 ts of the androgen receptor (AR) in external genitalia.

34 gages or is dislodged from the hermaphrodite genitalia.

35 n the oral cavity and 16.9% for the external genitalia.

36 pmental and evolutionary origins of external genitalia.

37 ydactyly, seizures, and hypoplastic external genitalia.

38 ing of the urethral orifice; and hypoplastic genitalia.

39 s; T. castaneum males have relatively simple genitalia.

40 differ in the anatomical complexity of their genitalia.

41 morphological diversification of insect male genitalia.

42 tgrowth or normal patterning of the external genitalia.

43 OR), suppressor with morphological effect on genitalia 1 (SMG1), and transformation/transcription dom

44 The human suppressor of morphogenesis in genitalia-1 (hSMG-1) protein kinase plays dual roles in

45 view images of high-ranking males and female genitalia [10].

46 g with suppressor with morphogenic effect on genitalia 5 (SMG5) and SMG7 but not SMG1 or SMG6.

47 ormal genital morphogenesis with hypoplastic genitalia, a single cloacal opening, and persistence of

48 structures such as the scalp, face, external genitalia, acral, periumbilical, and perineal areas.

49 te them in social encounters; their external genitalia also are highly masculinized.

50 chanisms by investigating divergence in male genitalia among populations differing in predator regime

51 t in abnormal development of the kidneys and genitalia and an array of pediatric problems including n

52 lso provide a more detailed map of the adult genitalia and analia with respect to the anterior/poster

53 , which gives rise to the sexually dimorphic genitalia and analia, sexual identity must be integrated

54 ectively, and produce the sexually dimorphic genitalia and analia.

55 contains primordia for both male and female genitalia and analia.

56 FGFR mutations, whereas those with ambiguous genitalia and disordered steroidogenesis should be recog

57 the evolutionary diversification of external genitalia and for the association between external genit

58 Shh knockout mice lack external genitalia and have a persistent cloaca.

59 e, the association of both undermasculinized genitalia and isolated male factor infertility with AR(G

60 whereas earlier disruptions cause ambiguous genitalia and later disruptions cause micropenis.

61 Asymmetric genitalia and lateralized mating behaviors occur in seve

62 s responded similarly to Shh inactivation in genitalia and limbs, suggesting that Shh may regulate gr

63 yers and cell types within the LUT, external genitalia and lower reproductive structures.

64 cialized sensory structures found within the genitalia and other mucocutaneous tissues(1-4).

65 hetic and parasympathetic innervation to the genitalia and other pelvic structures.

66 d be considered in the presence of ambiguous genitalia and partial androgen insensitivity.

67 er, which leads to severe distortion of male genitalia and prevents male mating.

68 a novel downstream target of AR in external genitalia and show that conditional deletion of Ihh inhi

69 e fusing palate, tooth buds, hair follicles, genitalia and skin.

70 digestive organs, respiratory tract, female genitalia and urinary tract, HR values increased signifi

71 eks of age displayed underdeveloped external genitalia and uteri.

72 eterosexual men did not prefer redder female genitalia and, by extension, that red is not a proxy sig

73 logical (number of hairs, tibia length, male genitalia) and chemical (cuticular hydrocarbons) differe

74 Drosophila melanogaster, the antennae, legs, genitalia, and analia make up a serially homologous set

75 cause disordered steroidogenesis, ambiguous genitalia, and Antley-Bixler syndrome (ABS), which has a

76 olar wrists, ankles, axillae, buttocks, male genitalia, and areolae.

77 opapular and erythematous rash in the groin, genitalia, and buttocks.

78 osophila genus, traits such as sperm length, genitalia, and gonad size are the most obvious differenc

79 s cause X-linked lissencephaly with abnormal genitalia, and insertion/missense mutations result in ep

80 of the metathoracic glands, male and female genitalia, and molecular markers.

81 tors, genes, gonadal hormones and receptors, genitalia, and social/environmental factors.

82 including intellectual disability, abnormal genitalia, and structural CNS malformations.

83 the primordia for the hindlimb and external genitalia, and switches from the epiblast/primitive stre

84 yields morphological defects in the testes, genitalia, and the antenna.

85 ons typically developed at flexural regions, genitalia, and the scalp, especially the psoriasiform le

86 ere fully masculinized, with testes and male genitalia, and were fertile, but sperm counts were reduc

87 o defects were observed in T. castaneum male genitalia, and while the male claspers of O. fasciatus w

88 is is recommended when treating the face and genitalia; and antifungal prophylaxis is not recommended

89 ctal septation, and modeling of the external genitalia; and internally, the emergence of basal epithe

90 Male and female external genitalia appear identical early in gestation.

91 The epandrial posterior lobes of male genitalia are a novelty of particular Drosophila species

92 ophy, incontinence, and ambiguous or variant genitalia are also discussed.

93 Insect male genitalia are among the fastest evolving structures of a

94 Malformations of the external genitalia are among the most common congenital anomalies

95 Birth defects of the external genitalia are among the most common in the world.

96 External genitalia are body appendages specialized for internal f

97 Distinctive, male Aneuretopsychina genitalia are evident from specimens in copulo, suppleme

98 found that overall, male and female external genitalia are largely composed of the same core cellular

99 ce from many animal taxa indicates that male genitalia are often under postcopulatory sexual selectio

100 The external genitalia are some of the most rapidly evolving morpholo

101 ale and female subordinates, including their genitalia, are remarkably monomorphic, as is their behav

102 at allow driving gene expression in the male genitalia as a tool to uncover the role of these genital

103 a limb-like developmental origin of external genitalia as the ancestral condition.

104 with testis maldescent, malformations of the genitalia at birth, and poor semen quality later in life

105 que cell populations in both male and female genitalia become apparent and are enriched with androgen

106 fants with intersex conditions and ambiguous genitalia being raised female, this surgery is often und

107 ies and X-linked lissencephaly with abnormal genitalia, but neurodevelopmental syndromes characterize

108 ere fully feminized, with ovaries and female genitalia, but showed a shortage of oocytes resulting in

109 Affected girls are born with ambiguous genitalia, but their circulating androgens are low, and

110 e incomplete masculinization of the external genitalia by disrupting AR function in males with androg

111 inalis Specifically, innervation of the male genitalia by the fifth and sixth segmental ganglia (the

112 These observations demonstrate that non-genitalia cells involved in feeding also mediate male se

113 nterior-posterior (a-p) limb axis and in the genitalia, consisting of a single bone in the zeugopod,

114 The fly genitalia contain sex-specific bristle hairs innervated

115 nd mechanosensory neurons (MSNs) at the male genitalia contribute to the regulation of copulation dur

116 Despite the importance of insect genitalia, descriptions of their genetic patterning have

117 In squamates, the genitalia develop directly from the budding hindlimbs, o

118 mammalian embryos, male and female external genitalia develop from the genital tubercle.

119 he genetic pathways governing early external genitalia development and urethra formation are poorly u

120 ry-adrenal axis is fully functional when the genitalia differentiate (see the related article beginni

121 changes in cell populations in the external genitalia during the critical morphogenetic window.

122 r of Tbx4, produces defects in hindlimbs and genitalia, establishing the importance of this limb-geni

123 we show that inactivation of Shh in external genitalia extends the cell cycle from 8.5 to 14.4 h, and

124 child abuse and either physical examination; genitalia; female, diagnosis; or sensitivity and specifi

125 sexual selection seems to favor larger male genitalia (females exhibited mating preference for males

126 ars, a physician performed pubertal staging [genitalia (G), pubarche (P), and testicular volume (TV)]

127 metric measurements of external and internal genitalia (group I, n = 47), analyzed pathology records

128 rved between p,p -DDE and Tanner stage 5 for genitalia growth or TV >/= 20 mL.

129 Tanner stage 5 for genitalia growth was attained a mean of 2.2 months (95%

130 sures of sexual maturity: Tanner stage 5 for genitalia growth, Tanner stage 5 for pubic hair growth,

131 ractice performing MMS on the head and neck, genitalia, hands, and feet region of Medicare Part B pat

132 f stages per case for MMS for head and neck, genitalia, hands, and feet skin cancers, which may repre

133 Sex assignment in the newborn with ambiguous genitalia has been based on the adequacy of the phallus

134 ow that the developmental origin of external genitalia has shifted through evolution, and in some tax

135 ospadias, chordee, micropenis, and ambiguous genitalia, have risen sharply in recent decades, but the

136 receptor-positive inflammatory cells in the genitalia help explain the inability of anti-HSV-2 thera

137 Infants born with ambiguous genitalia [henceforth referred to as Disorder of Sex Dev

138 spotted hyenas are known for their male-like genitalia, high levels of aggression, and dominance over

139 Masculinization of the external genitalia in humans is dependent on formation of 5alpha-

140 Development of external genitalia in mammalian embryos requires tight coordinati

141 Normal development of male genitalia in mammals depends on androgen action.

142 an altered developmental route for external genitalia in mammals, while preserving parts of the ance

143 during embryonic development of the external genitalia in mice, and that this regulation is mediated

144 during embryonic development of the external genitalia in mice.

145 ro virilization of the affected female fetus genitalia in the classical form of CAH.

146 gulated by the androgen receptor (AR) in the genitalia in the presence of the p300 coactivator, ident

147 While most birds do not have external genitalia, in a small number of species the males have p

148 Brennan provides an overview of bird genitalia, including speculation about the evolutionary

149 The size of external genitalia increased in both sexes, but they remained fer

150 rtship, the male repeatedly licks the female genitalia, independently of ovipositor extrusion, and th

151 ion of Bmp signaling in duck (an anseriform) genitalia induces a galliform-like pattern of apoptosis.

152 ferent mesenchymal cells to respond to these genitalia-inducing signals.

153 We propose that induction of external genitalia involves an epithelial-epithelial interaction

154 The rapid, divergent evolution of genitalia is a general trend in animals and likely influ

155 Undermasculinization of the male genitalia is a rare example of a non-neurodegenerative,

156 Development of the mammalian external genitalia is controlled by a network of signaling molecu

157 A thorough inspection of the groin and genitalia is imperative in black organ transplant recipi

158 pmental outcomes for children with ambiguous genitalia is lending direction to longitudinal outcomes

159 e origin of cells that give rise to external genitalia is unknown.

160 Although congenital external genitalia malformations represent the second most common

161 males (immature) versus males with rotating genitalia (maturing) provides insight into possible mole

162 Male genitalia may experience more rapid, divergent evolution

163 arly for organisms that cannot retract their genitalia, may also prove important.

164 ory networks driving morphogenesis of animal genitalia must integrate sexual identity and positional

165 Las was detected in genitalia of both sexes and also in eggs of infected fem

166 ning and routine examination of the anus and genitalia of children.

167 derived morphological novelty present in the genitalia of D. melanogaster employs an ancestral Hox-re

168 osterior lobe, a novel structure in the male genitalia of Drosophila melanogaster.

169 a vast matrix associated with the developing genitalia of lobed and non-lobed species.

170 s prevalence and persistence in the external genitalia of men enrolled in the prospective HPV Infecti

171 ens of some beetles or photoreceptors on the genitalia of some butterflies.

172 Circulating levels of testosterone, external genitalia, or fertility were not altered in pes-ARKO mic

173 in the relative position of the cloaca, the genitalia organizing centre.

174 of enhancer activity in embryonic limbs and genitalia overlap heavily.

175 atient initially diagnosed with XY ambiguous genitalia/partial androgen insensitivity syndrome, who w

176 zed by necrotizing infection of the external genitalia, perineum, and perianal region.

177 Genitalia play an important role in the life histories o

178 Tactile cues delivered to the abdomen and genitalia play the larger role in females, as even headl

179 or mating status males salivate onto female genitalia pre-, during, and post-copulation.

180 of the pediatric pelvis, including ambiguous genitalia, prepubertal bleeding, primary amenorrhea, pel

181 ctor SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN7.

182 erence for pinker genital images with redder genitalia rated significantly less sexually attractive.

183 Proper formation of the external genitalia requires a highly orchestrated process that in

184 Inhibition of Bmp signaling in chick genitalia rescues cells from apoptosis and prevents phal

185 telorism, pulmonary valve stenosis, abnormal genitalia, retardation of growth and deafness), an autos

186 Pulmonic valvular stenosis, Abnormalities of genitalia, Retardation of growth, and Deafness.

187 hypertelorism, Pulmonary stenosis, Abnormal genitalia, Retardation of growth, sensorineural Deafness

188 es a suite of physiological changes, such as genitalia rotation that is necessary for successful mati

189 talia as a tool to uncover the role of these genitalia specific neurons in copulation.

190 mporal specificities that are separated by a genitalia-specific enhancer.

191 entration and male pubertal onset defined by genitalia staging, although not by testicular volume.

192 onset was based on testicular volume and on genitalia staging.

193 PV-16 variants observed at the male external genitalia suggest differences in the natural history of

194 in the expression of this gene in developing genitalia suggest that cis-regulatory changes in trn und

195 ights into the morphogenesis of the external genitalia that could be used to understand diseases asso

196 ized by chronic pain in the pelvic region or genitalia that is often accompanied by urinary frequency

197 adias is a congenital defect of the external genitalia that results from failure of urethral tube clo

198 AR function can result in undermasculinized genitalia that vary from a completely female appearance

199 arly phase, the embryonic anlage of external genitalia, the genital tubercle (GT), is morphologically

200 an altered Hoxd gene regulation in external genitalia, the limb-associated bimodal HoxD chromatin st

201 conveying information from the male external genitalia to MRF, and (2) ascending bilateral projection

202 invertebrates in which males use hypodermic genitalia to penetrate their partner's body wall during

203 conveying somatosensory information from the genitalia to the brain during sexual activity, the mesol

204 e vagus nerve conveys VCMS directly from the genitalia to the brain.

205 vary from neonatal salt wasting and atypical genitalia, to adult presentation of hirsutism and irregu

206 Serial MR imaging of the external genitalia was performed in 12 healthy sexually functiona

207 ve the sexually dimorphic development of the genitalia, we performed genome-wide transcriptional prof

208 ental species have smaller bodies and longer genitalia, which facilitate sneak or coercive mating and

209 ound in X-linked lissencephaly with abnormal genitalia, which typically includes severe brain malform

210 s with complete external and internal female genitalia, which, however, were significantly smaller th

211 s who had intersex conditions with ambiguous genitalia who were living as female from clinical (n=15)

212 combining a taxonomic key based on the male genitalia with DNA barcoding, using a cytochrome c oxida

213 ealed variation in the structure of the male genitalia within and among populations of this species s

214 oration of sensation to hands, perineum, and genitalia would be a significant improvement for a spina