ライフサイエンスコーパス: genome sequence

1 s with genetic information (imputed or whole-genome sequencing).

2 e Apogee wheat variety, which has no current genome sequence.

3 he data to generate a chromosome-scale draft genome sequence.

4 tegrated vector sequence and the neighboring genome sequence.

5 fic to the virus in question, other than its genome sequence.

6 e EBOV genome exists around a dominant viral genome sequence.

7 om C. difficile-positive stool samples, were genome sequenced.

8 leles for each gene using 1,991 contig-level genome sequences.

9 links using Mycobacterium tuberculosis whole-genome sequences.

10 ith three datasets from fungal and bacterial genome sequences.

11 ere certainly resolved using the complete cp genome sequences.

12 Cultured isolates underwent whole-genome sequencing.

13 K1 open reading frame Sanger and KSHV whole-genome sequencing.

14 ng multilocus typing of five genes and whole-genome sequencing.

15 ic test with whole-exome sequencing or whole-genome sequencing.

16 diabetes, six by exome sequencing and one by genome sequencing.

17 ily selected, from single mutations to whole-genome sequencing.

18 cing panels as well as whole-exome and whole-genome sequencing.

19 e exome sequencing, and more recently, whole genome sequencing.

20 gene sequencing and most recently, exome and genome sequencing.

21 ources in NYS were characterized using whole-genome sequencing.

22 Using data from 138,632 exome and genome sequences(2), we developed gene variation intoler

23 Whole genome sequencing (30X) and digital droplet PCR (ddPCR)

24 proliferation pathways are influenced by the genome sequence, 3D organization and chromatin accessibi

25 mbers of individuals have undergone elective genome sequencing, a comprehensive study surveying genom

26 The comparison of whole-genome sequences across 10 additional Formica species re

27 With further, more accurate human genome sequencing, additional mutation hotspots, mechani

28 Whole genome sequencing alerted us to the existence of greater

29 d short-read aligner, can compute WGS (whole-genome sequencing) alignments ten times faster than comp

30 n composition that allow OGT prediction from genome sequence alone.

31 ches that reduced the complexity and time of genome sequencing along with development of gene editing

32 e recent publication of a high-quality wheat genome sequence, alongside gene expression atlases, vari

33 However, the wide adoption of whole-genome sequencing also poses new challenges for public-h

34 Here we performed whole-genome sequencing analyses of 426 individuals-comprising

35 The combination of near to real-time whole-genome sequence analysis and epidemiology resulted in re

36 Whole-genome sequence analysis demonstrated the Houston patien

37 Our genome sequence analysis identifies expansions of protei

38 Whole genome sequence analysis was performed on a subset of 76

39 growth of ESBL-E was quantified and a whole-genome sequence analysis was performed.

40 microbial strain safety assessment via whole-genome sequence analysis.

41 n on canine chromosome 33, followed by whole-genome sequencing analysis that revealed a long interspe

42 e approach, followed by a more refined whole genome sequencing analysis.

43 Here, we report genome sequence and annotation of a South African QPM li

44 nome Reference Bank (MGRB), comprising whole genome sequence and phenotype of 2570 elderly Australian

45 visualized along the linear map of the viral genome sequence and programmatically downloaded in stand

46 The genome sequence and protein structure of the 2019-novel

47 sought to comprehensively investigate whole-genome sequence and RNA sequence from human bronchial ep

48 of the gene models in the S. lycopersicoides genome sequence and RNA-Seq data, two of the eight genes

49 The increasing availability of cancer whole genome sequences and functional genomics data from the E

50 rom comprehensive sets of AMR genes or whole genome sequences and may not be suitable for use when ge

51 ssociated viruses with at least 10 published genome sequences and rapidly incorporated an additional

52 aution to address systematic biases in whole-genome sequencing and alignment.

53 re confirmed using pathogen isolation, whole-genome sequencing and antibiotic susceptibility testing,

54 Here we report genome sequencing and assembly for true jellyfish Sander

55 hts several of the opportunities provided by genome sequencing and bioinformatics, challenges associa

56 , fluorescence-activated cell sorting, whole-genome sequencing and data analysis.

57 provides results on the integration of whole-genome sequencing and deep phenotyping for clinical asse

58 Through a combination of whole-genome sequencing and transcriptomics, we showed that to

59 Transcriptomics, genome sequencing, and metabolomics analyses in these Zn

60 [range 20 to 89+]; 70.6% European) had whole-genome sequencing, and were deeply phenotyped using meta

61 es mutational signatures identified by whole genome sequencing, and will ultimately allow the study o

62 omic data from whole exome sequencing, whole genome sequencing, and/or array-based imputation.

63 Thus, using a cohort-based whole-genome-sequencing approach in the diagnosis of PID can i

64 Resources such as mutant collections and genome sequences are now available for these crops, maki

65 Whole-exome and whole-genome sequencing are becoming financially feasible but

66 l resistance determination, such as by whole-genome sequencing, are required.

67 However, the increasing application of whole-genome sequencing as a diagnostic tool is leading to the

68 ected, adopting whole-exome sequencing/whole-genome sequencing as a first-line test should be conside

69 and genome assembly increasingly facilitate genome sequencing as a means of characterizing new varie

70 sistance genes from various formats of whole genome sequences based on the CARD or ResFinder database

71 and duplications were genotyped using whole-genome sequencing-based data.

72 odel of a reference strain; (ii) compare the genome sequence between a reference strain and target st

73 ineages and sublineages based on their whole-genome sequences, but little is known about the impact o

74 Applying SigProfilerSimulator to 2144 whole-genome sequenced cancers reveals: (i) that most doublet

75 ing for five lipid traits in two UK10K whole genome sequencing cohorts, hypothesizing that cis-expres

76 we analyse 208 publicly available SARS-CoV-2 genome sequences collected during the early outbreak pha

77 no reference maps of SVs from high-coverage genome sequencing comparable to those for SNVs.

78 A(H1N1) variant cases were resolved by full genome sequence comparison of the variant viruses to swi

79 Whole-genome sequencing confirmed distinct species identities

80 Surveillance strategies based on whole genome sequencing could help with the early identificati

81 Whole genome sequencing coupled with an outbreak-strain-specif

82 With the large amount of genome sequence data available today, particularly on ba

83 Examining whole-genome sequence data describing a chronic case of influe

84 we examine this question through the lens of genome sequence data for five species of southern capuch

85 We analyzed whole-genome sequence data from 165 primary membranoproliferat

86 rhesus macaque (Macaca mulatta) using whole-genome sequence data from 32 individuals in four large p

87 ly, we integrate this information with whole-genome sequence data from 375 individual mosquitoes to i

88 By analysing high-coverage genome sequence data from 4 major colour pattern loci sa

89 rapid-flowering mutant was done using whole-genome sequence data from bulked DNA from a segregating

90 Genome sequence data have been used to evaluate the size

91 The current wealth of genome sequence data offers an opportunity to better und

92 Analysis of transcriptome/genome sequence data revealed loss of NPY/NPF-type signa

93 -gene-disrupting variants encoded from whole genome sequence data to ASD; however, this previous appr

94 ive to obtain genotype data and indeed whole genome sequence data, the question then becomes to defin

95 Genetic variants were examined using whole-genome sequencing data among survivors of African ancest

96 s (PCAWG) Consortium, which aggregated whole-genome sequencing data and RNA sequencing from a common

97 Short-read whole-genome sequencing data are often applied to large-scale

98 Whole genome sequencing data did not identify a strain genotyp

99 Our interrogation of the whole-genome sequencing data for 215 breast tumors catalogued

100 Using public whole-genome sequencing data from 2,606 samples from different

101 e Genomes Consortium, which aggregated whole-genome sequencing data from 2,658 cancers across 38 tumo

102 Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 38 tumo

103 RNA-seq, and then integrate these with whole genome sequencing data from 232 OCs.

104 s (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor

105 We analyze whole-genome sequencing data from 268 patients to catalog gene

106 Whole genome sequencing data from cases and controls were comp

107 We applied SBMClone to single-cell whole-genome sequencing data from two breast cancer patients o

108 ariant caller utilizing low-depth (8X) whole-genome sequencing data generated by Oxford Nanopore Tech

109 ing dense imputation from multi-ethnic whole-genome sequencing data in admixed Hispanics/Latinos.

110 sequence and structural diversity from whole-genome sequencing data remains highly challenging.

111 iers have successfully been applied to whole-genome sequencing data to identify genetic determinants

112 We combined genome sequencing data with single-cell mRNA sequencing

113 Using matched whole-genome sequencing data, we associated several categories

114 Using the GTEx whole genome sequencing data, we identify 20,545 high-quality

115 -80% of indels detected in human brain whole-genome sequencing data.

116 ructural variant (SV) breakpoints from whole-genome sequencing data.

117 rately assemble organelle genomes from whole genome sequencing data.

118 ,658 tumors from 38 cancer types using whole-genome sequencing data.

119 Genome sequencing did not identify any genetic differenc

120 lex manner in which natural selection shapes genome sequences during speciation.

121 n detected as the result of extensive cancer genome-sequencing efforts and are linked to a restricted

122 Genome sequencing enabled us to identify a chaperone-ush

123 It highlights the role of whole-genome sequencing, expanded phenotypic drug susceptibili

124 Recently, with the number of genome sequences exponentially increasing, multi-strain

125 In this work, we present the full genome sequence for 17 SARS-CoV-2 isolates corresponding

126 facilitate analyses of high-coverage (~30x) genome sequences for wild-caught individuals representin

127 US) is essential in clinical applications of genome sequencing for diagnosis and personalized care.

128 A key goal of whole-genome sequencing for studies of human genetics is to in

129 nteric diarrhea and endorse the use of whole-genome sequencing for sustained surveillance of NTS inte

130 We performed whole genome sequencing for two American minks with Moyle (m/m

131 tigations with analysis of mumps virus whole genome sequences from 201 infected individuals, focusing

132 Adding shotgun genome sequences from 40 accessions enables identificati

133 We present 929 high-coverage genome sequences from 54 diverse human populations, 26 o

134 We obtained 6078 near full-length HIV-1C genome sequences from 6075 PLWH.

135 Here we analyse high-coverage whole-genome sequences from 97,691 participants of diverse anc

136 Here, we generate 649 SARS-CoV-2 genome sequences from infected patients in New Zealand w

137 This study used imputed whole-genome sequencing from the Trans-Omics for Precision Med

138 across the tree of life, including reference genome sequence, gene models, transcriptional data, gene

139 Massive genome sequencing has allowed extraction of specific fea

140 Viral genome sequencing has emerged as a powerful approach to

141 Whole-genome sequencing has enhanced surveillance and facilita

142 Genome sequencing has established clinical utility for r

143 An explosion of genome sequencing has facilitated a deep understanding o

144 Genome sequencing has fundamentally changed how plant bi

145 The application of exome and genome sequencing has greatly improved the rate of genet

146 As access to whole-genome sequencing has grown, greater amounts of molecula

147 Genome sequencing has identified a host of deleterious g

148 The rapid progress in genome sequencing has led to high availability of genomi

149 Genome sequencing has revealed an increasing number of g

150 m k-mer distributions representing reference genome sequences have a rich history in the classificati

151 and characterizing the viral load, RSV whole-genome sequencing, host immune response, and transcripto

152 Phylogenetic analysis of genome sequences identified two clusters - one related t

153 Here, we describe in situ genome sequencing (IGS), a method for simultaneously seq

154 address these challenges by performing whole-genome sequencing in a large PID cohort of 1,318 partici

155 Rapid trio genome sequencing in family 1 and exome sequencing in fa

156 Whole genome sequencing in multiplex families, proband-parent

157 Whole-genome sequencing in one affected dog and its obligatory

158 and PRSS56 testing in 20 families and whole-genome sequencing in one family.

159 rated and analyzed, and how SARS-CoV-2 whole-genome sequencing, in combination with epidemiological d

160 lity chromosomal breaks and loss of specific genome sequences including a major tandem repeat of 120

161 nanopore sequencing technology, producing a genome sequence indistinguishable to the one determined

162 We assemble the 1.07 Gb genome sequence into 24 chromosomes and annotate 32,690

163 Our work shows that genome sequencing is a powerful epidemiological tool to

164 (RP17) was delineated through genotyping and genome sequencing, leading to the identification of stru

165 entary features, generated purely from virus genome sequences, leads to improved accuracy for a range

166 The resulting 680 genome sequences led to the discovery of a pan-susceptib

167 plement many currently defined statistics of genome sequence (making the statistics' relationship to

168 Availability of genome sequence, molecular, and clinical phenotype data

169 shed sequences, as well as a set of new OROV genome sequences obtained from patients in Ecuador, repr

170 cing technologies, we provide a high-quality genome sequence of a cultivated accession of white lupin

171 The reported first genome sequence of a tropical rubber tree pathogen R. mi

172 We report the draft genome sequence of Alexander Fleming's original fungal i

173 f ever required, we have determined the full genome sequence of all our distinct samples of RPV, incl

174 We previously completed a draft genome sequence of an African clade (clade III) strain c

175 Biosciences SMRT sequencing to determine the genome sequence of C. diphtheriae BQ11 and mechanism of

176 Recent studies have uncovered whole genome sequence of SARS-CoV-2 (causing COVID-2019).

177 , we present a high-quality chromosome-scale genome sequence of SP LA2093.

178 Here we report the 409-megabase genome sequence of the blue-petal water lily (Nymphaea c

179 We determined the genome sequence of the oil field isolate Sulfurimonas sp

180 proteins in our mass spectrometry analyses, genome sequence of the phage G host, and host range of p

181 Here, we assembled a high-quality genome sequence of ~542 Mb and found that retrotransposo

182 Both strategies yielded closed genome sequences of 1,914,862 bp, identical in length an

183 We present the first whole-genome sequences of B. pseudomallei isolates from Myanma

184 We obtained complete genome sequences of CCHFV directly from the tick reservo

185 ons were relatively higher in the SARS-CoV-2 genome sequences of Europe (43.07%) followed by Asia (38

186 ead sequencing, we obtained chromosome-level genome sequences of four Clade 2 isolates, which display

187 Here we analyse whole-genome sequences of males from native populations of six

188 owever, experimentally determining the whole-genome sequences of many diverse organisms was practical

189 ophies and apply it to a series of available genome sequences of over 1,300 Gram-negative strains.

190 analyzed 2,492 complete and/or near-complete genome sequences of SARS-CoV-2 strains reported from acr

191 Whole-genome sequences of seven phage susceptible A. baumannii

192 t enriched the existing database of complete genome sequences of SRMVs with Pakistan-originated strai

193 Through whole-genome sequencing of 13 melanoma metastases sampled at a

194 Therefore, whole-genome sequencing of 756 child-parent trios of European,

195 Shallow whole-genome sequencing of 777 biopsies, sampled from 88 patie

196 ccurring on palms, soles or nail beds, whole genome sequencing of 87 tumors with matching transcripto

197 Genome sequencing of actinomycetes reveals an untapped r

198 We conducted whole-genome sequencing of all 1,575 available GAS macrolide-r

199 High-throughput genome sequencing of both isolates and metagenomic sampl

200 Here we have performed whole genome sequencing of consecutive M. tuberculosis isolate

201 SWGA enables the successful whole genome sequencing of samples with low parasite density (

202 Whole genome sequencing of select transformants demonstrated t

203 However, genome sequencing of specimens is challenging because of

204 Full genome sequencing of the ANDV strain involved in this ou

205 Recent genome sequencing of the constitutive model CAM species

206 Viral genome sequencing of the paired first-positive and reinf

207 MIC, pDST and whole genome sequencing of the pncA, rpsA and panD genes were

208 We performed whole-genome sequencing of the SKBR3 breast cancer cell line a

209 Single-cell barcoding technologies enable genome sequencing of thousands of individual cells in pa

210 Metagenomic techniques have enabled genome sequencing of unknown viruses without isolation i

211 ion AST with seven antibiotics and for whole-genome sequencing of up to 5,000 isolates.

212 Using whole-genome sequencing of zebrafish mutants isolated in an un

213 We performed whole-genome sequencing on food and clinical isolates.

214 We performed whole genome sequencing on isolates from early pediatric CF pu

215 However, working with whole genomes sequenced over several years in different sequen

216 and assemble high quality complete consensus genome sequences, permitting high-resolution inference o

217 intervention in a model that compared whole-genome sequencing plus current practice versus current p

218 Whole-genome sequencing projects are increasingly populating t

219 ger sequence reads, which when used in whole-genome sequencing projects have yielded better repeat re

220 roximately 3.6 million DHSs within the human genome sequence, providing a common coordinate system fo

221 Using 76 whole genome sequences representing 21 orders spanning more th

222 Here, we exploit available genome sequence resources to investigate triterpene bios

223 istance (AMR), classic genotyping, and whole-genome sequencing results.

224 Whole genome sequencing revealed differences in putative virul

225 Analysis of chromosome-scale mango genome sequences reveals photosynthesis and lipid metabo

226 Whole-genome sequencing reveals the absence of off-target muta

227 APOR retrieved references for 257 real whole-genome sequencing samples with a mean of >99.8% identity

228 tients were examined by culture, qPCR, whole genome sequencing, serotyping, and reverse transcription

229 Viral genome sequencing showed that the majority of HCWs had t

230 Cancer genome-sequencing studies have revealed a remarkably hig

231 nd assess the impact of affordable and rapid genome sequencing systems increasingly being deployed in

232 The success of genome sequencing techniques has resulted in rapid explo

233 ve evolved through cis-regulatory changes in genome sequence that influence the magnitude, timing and

234 gies and the availability of increasing crop genome sequences, the goal of breeding next-generation c

235 The accelerating pace of genome sequencing throughout the tree of life is driving

236 unmapped reads can be recovered for a given genome sequenced to ~40X coverage.

237 Here, we use 490 Argentinian V. cholerae genome sequences to characterise the variation within, a

238 We used whole-genome sequences to compare genomes from periods before

239 In this study, we used whole-genome sequencing to analyze a large collection of 451 d

240 al surveillance with influenza A virus (IAV) genome sequencing to identify and contain a large IAV ou

241 We performed whole-exome and shallow whole-genome sequencing to identify genes and pathways prefere

242 d by foldback inversions combined with whole-genome sequencing to study their formation.

243 Here we use C. elegans whole genome sequencing to systematically quantify the contrib

244 lonization on NF admission, we applied whole-genome sequencing to track the spread of 4 ARO species a

245 For diploid human genomes sequenced to 30x HiFi coverage, HiCanu achieved

246 nces, and shown that, for more than half the genomes sequenced, translation of the F protein requires

247 hods: Within a prospective multicenter whole-genome sequencing trial (NCT01855477), 69 mPC patients u

248 agents, as well as in whole-exome and whole-genome-sequenced tumors identified signatures highly spe

249 ot randomized and received ultra-rapid whole-genome sequencing (urWGS).

250 conventional RT-PCR based methods and whole genome sequenced using the Illumina MiSeq platform.

251 mic data, particularly when annotating whole-genome sequencing variants against a huge database with

252 ons and by analysing the association between genome sequence variation and exon inclusion across the

253 was sequenced, using a PacBio platform; the genome sequence was assembled de novo, using HGAP.

254 The availability of whole genome sequences was expected to supply essentially unli

255 Virus identical to SARS-CoV-2 in full-genome sequences was isolated from the infected lung and

256 Whole genome sequencing was performed on 20 matched blood and

257 etect potential transmission clusters, whole genome sequencing was performed on nasopharyngeal swabs

258 Long-read whole genome sequencing was performed using Pacific Bioscience

259 -PCR primers/probe were developed, and whole genome sequencing was performed.

260 Whole genome sequencing was used to uncover a frame-shift inse

261 Here, by whole-exome/genome sequencing we identify heterozygous, autosomal-do

262 Using whole-genome sequencing we now identified a single rare nonsyn

263 By parent-offspring whole genome sequencing, we estimate a mutation rate (3.38 x 1

264 a combination of short- and long-read whole-genome sequencing, we found no significant association b

265 Through genome sequencing, we identified 2 different large chrom

266 Using whole genome sequencing, we identified a heterozygous frameshi

267 Using clinical whole genome sequencing, we show that AR binding sites have a

268 nucleotide polymorphisms identified by whole genome sequencing were used to design a specific polymer

269 We performed whole genome sequence (WGS) analysis of lung function and COPD

270 Whole genome sequence (WGS) data could transform our ability t

271 Multilocus Sequence Typing (MLST) and Whole Genome Sequencing (WGS) analysis.

272 me wards within 7 days were chosen for whole-genome sequencing (WGS) and a phylogenetic analysis was

273 enomic landscape of myeloma using deep whole-genome sequencing (WGS) and develop a model that identif

274 We performed whole-genome sequencing (WGS) and pan-genome analysis on all b

275 Here, we leverage whole-genome sequencing (WGS) and whole-genome bisulfite seque

276 Whole-genome sequencing (WGS) can support surveillance by pinp

277 Whole-genome sequencing (WGS) data from 853 rhesus macaques id

278 Bulk whole genome sequencing (WGS) enables the analysis of tumor ev

279 Whole-genome sequencing (WGS) is now routinely performed in cl

280 Here we perform whole-genome sequencing (WGS) of 103 UM from all sites of the

281 We undertook whole-genome sequencing (WGS) of 660 pneumococcal isolates col

282 Whole-genome sequencing (WGS) of cfDNA allowed ultra-sensitive

283 We present SNVs discovered by whole genome sequencing (WGS) of three Moroccans.

284 n neuroblastoma using a combination of whole-genome sequencing (WGS) of tumor-normal pairs (n = 135)

285 nt here an unbiased approach combining whole genome sequencing (WGS) with patient-induced pluripotent

286 typing results by latex agglutination, whole-genome sequencing (WGS) with PneumoCaT, and DNA microarr

287 ew sequencing approaches, particularly whole-genome sequencing (WGS), have dramatically changed the l

288 rative genomic hybridization (CGH) and whole-genome sequencing (WGS), have greatly advanced the ident

289 Whole genome sequencing (WGS), on the other hand, allows for i

290 samples based on low-coverage clinical whole-genome sequencing (WGS).

291 on to whole-exome sequencing (WES) and whole-genome sequencing (WGS).

292 , but there are plans for implementing whole genome sequencing (WGS).

293 s performed for specific pathogens and whole-genome sequencing (WGS).

294 and characterization were performed by whole genome sequencing (WGS).

295 throughput genotyping (31,811 SNPs) or whole-genome sequencing (WGS, 8.7 million SNPs).

296 la oxytoca infection was identified by whole-genome sequencing (WGS; later found to be part of a clus

297 Established methods for whole-genome-sequencing (WGS) technology allow for the detecti

298 solubility limit were then analyzed by whole genome sequencing, which revealed prevalent point mutati

299 methods using both real and synthetic whole-genome sequencing, whole-exome sequencing, and deep targ

300 r submission and the analysis of a new whole-genome sequence will take approximately 1 min.