ライフサイエンスコーパス: genotoxicity

1 vide additional insight into benzene-induced genotoxicity.

2 A repair in preventing S. pneumoniae-induced genotoxicity.

3 netic factors that influence benzene-induced genotoxicity.

4 e, 14 was also negative in the AMES test for genotoxicity.

5 sferases that were inversely correlated with genotoxicity.

6 HOIP as a key regulator of cisplatin-induced genotoxicity.

7 itors were discovered that react strongly to genotoxicity.

8 ess magnitude and number of effects) with no genotoxicity.

9 city in normal human fibroblasts and with no genotoxicity.

10 yme activities with limited cytotoxicity and genotoxicity.

11 1 micronucleus assays were applied to assess genotoxicity.

12 linked to the host cell biology of systemic genotoxicity.

13 lobal biological effects such as toxicity or genotoxicity.

14 compared to that of BG, but it presented no genotoxicity.

15 lar oxidative stress, and systemic leukocyte genotoxicity.

16 y unrecognized role in cellular responses to genotoxicity.

17 tment resulted in a decrease in toxicity and genotoxicity.

18 t of compound 29 was discontinued because of genotoxicity.

19 ng is crucial for predicting their potential genotoxicity.

20 ibility of epithelial cells to 4-HNE-induced genotoxicity.

21 st levels of mammalian cell cytotoxicity and genotoxicity.

22 the molecular mechanisms of asbestos-induced genotoxicity.

23 tioxidant status, DNA damage and bone marrow genotoxicity.

24 owth and resistance to gefitinib, U0126, and genotoxicity.

25 o reduce their potential posttranscriptional genotoxicity.

26 omosomal loci with high fidelity and without genotoxicity.

27 g that may play a role in enhanced etoposide genotoxicity.

28 assay (CA) is a sensitive/simple measure of genotoxicity.

29 extensively associated with mutagenicity and genotoxicity.

30 S), indicating the broad relevance of HRR to genotoxicity.

31 lication and contribute to acrolein-mediated genotoxicity.

32 y transfer (LET) radiation-induced bystander genotoxicity.

33 n arsenic-induced chromosome instability and genotoxicity.

34 ricultural chemicals and drugs for potential genotoxicity.

35 eripheral blood cells were counted to assess genotoxicity.

36 poration into the genome and thereby reduces genotoxicity.

37 carcinogenicity and 82.3% AUC for predicting genotoxicity.

38 ated with unintended genomic alterations and genotoxicity.

39 our mechanistic model for colibactin-induced genotoxicity.

40 on have focused especially on DNA damage and genotoxicity.

41 lyzed fruit powders showed acute toxicity or genotoxicity.

42 inery and caused increased stress leading to genotoxicity.

43 of insertional bias, contributing to reduced genotoxicity.

44 l compounds with varying carcinogenicity and genotoxicity.

45 utes a major human toxicity pathway known as genotoxicity.

46 C-binding factor and reduces its insertional genotoxicity.

47 for the bacteria to circumvent self-induced genotoxicity.

48 M and BAN expressed a potentiating effect in genotoxicity.

49 rtance of long-term monitoring for potential genotoxicity.

50 ty that sensitize cancer cells to additional genotoxicity.

51 BPs were the driving agents of the predicted genotoxicity.

52 mation of reactive oxygen species (ROS), and genotoxicity.

53 This intervention decreased systemic genotoxicity, a response associated with reduced basal l

54 d oligomers has been performed and showed no genotoxicity alert for linear or cyclic molecules.

55 Cyto-genotoxicity (Ames and micronucleus assays) and potentia

56 zation, the cis-isomer can display increased genotoxicity; an alarming concern for current cinnamate

57 of aldo-keto reductases and its role in the genotoxicity and carcinogenesis of B[a]P currently are u

58 r, the mechanisms involved in TiO(2)-induced genotoxicity and carcinogenicity have not been clearly d

59 ly play an important role with regard to the genotoxicity and carcinogenicity of formaldehyde.

60 for predicting chemical carcinogenicity and genotoxicity and characterizing modes of actions (MoAs)

61 by AKRs in lung cells leads to ROS-mediated genotoxicity and contributes to lung carcinogenesis.

62 d as a rapid in chemico screen for potential genotoxicity and cytotoxicity in mammalian cells exposed

63 te that recapitulates the previously assumed genotoxicity and cytotoxicity.

64 opoisomerase II activity, thereby leading to genotoxicity and cytotoxicity.

65 are linked to intestinal barrier disruption, genotoxicity and deleterious inflammation.

66 rely dependent upon aryl-hydrocarbon-induced genotoxicity and does not involve direct aryl-hydrocarbo

67 optosis is mediated by upstream NO and ONOO- genotoxicity and downstream p53 and Fas activation and i

68 Estrogen metabolite-mediated genotoxicity and induction of a stem cell/progenitor cel

69 es direct evidence that AlkB suppresses both genotoxicity and mutagenesis by physiologically realisti

70 t and reliable methods for detecting exhaust genotoxicity and mutagenicity are needed to avoid the wi

71 ered the ultimate carcinogen due to its high genotoxicity and mutagenicity attributed to its ability

72 ducts induce a significantly higher level of genotoxicity and mutagenicity in nucleotide excision rep

73 portance of different forms of DNA damage in genotoxicity and mutagenicity of Cr(VI) activated by phy

74 '-deoxyguanosine (4-HNE-dG) adducts, but its genotoxicity and mutagenicity remain elusive.

75 3-epsilonG was used to quantify directly its genotoxicity and mutagenicity.

76 lean in vitro toxicity profile, including no genotoxicity and no bone marrow toxicity at the highest

77 ion of acetylcholinesterase (AChE) activity, genotoxicity and oxidative stress using human blood cell

78 of AAV-mediated gene therapy that influence genotoxicity and suggest that these features should be c

79 tion intermediates mediates oncogene-induced genotoxicity and that limiting such processing to mitosi

80 The stability of DCH, combined with its genotoxicity and tumorigenic properties make it an impor

81 by S. pneumoniae in vivo contributes to its genotoxicity and virulence.

82 suppressing tumor growth without displaying genotoxicity and with little toxicity to normal cells.

83 dent cell death in cancer cells with minimal genotoxicity and without evident toxicity toward normal

84 eus is the main target for radiation-induced genotoxicity and, as fewer cells are directly damaged, t

85 rogen activities), reactive modes of action (genotoxicity) and adaptive stress response pathway (oxid

86 he transit toxicity exhibited as DNA stress (genotoxicity) and membrane stress during the degradation

87 DNA so as to warrant investigation of their genotoxicity, and both anomers will be present during th

88 e assays can be used to screen chemicals for genotoxicity, and knowledge about DNA repair capacity ha

89 ysfunction, inflammatory cascade, apoptosis, genotoxicity, and ultimately necrosis of neuronal cells.

90 f mammary carcinogenicity, estrogenicity, or genotoxicity; and (3) not currently measured in large bi

91 tathion S-transferase, metallothionein), and genotoxicity are the most sensitive tools to highlight t

92 s our own efforts to produce high-throughput genotoxicity arrays and LC-MS/MS approaches to reveal po

93 Results support the value of the ECL genotoxicity arrays together with toxicity bioassays for

94 he optimum dose significantly decreased soil genotoxicity, as evaluated with either mutant cell line.

95 is required for host responses to bacterial genotoxicity, as mutations of OGG1 acetylation sites inc

96 B lymphoblastoid cells to test the potential genotoxicity, as well as the cytotoxicity, of toxic spec

97 creased MeIQ activation based on the E. coli genotoxicity assay and 12-fold enhanced catalytic effici

98 at provides biological relevance to positive genotoxicity assay data, particularly for in vitro chrom

99 m comet tests, suggesting that the molecular genotoxicity assay is suitable for genotoxicity detectio

100 s of the in vivo erythroid micronucleus (MN) genotoxicity assay, thus enabling increased throughput a

101 In parallel, genotoxicity assays (Ames and micronucleus assays) and t

102 Finally, because TDCPP-specific genotoxicity assays have, for the most part, been negati

103 Several in vitro genotoxicity assays indicated that the selected compound

104 In silico genotoxicity assessment of all identified oligomers has

105 study reports a comparative and mechanistic genotoxicity assessment of four engineered nanomaterials

106 The genotoxicity associated with the metabolic reduction of

107 ts direct transforming function, it displays genotoxicity at several distinct levels.

108 Toxicity and genotoxicity bioassays can supplement chemical analysis-

109 es, based on bioluminescent Escherichia coli genotoxicity bioreporters, sprayed onto the surface of a

110 ding of how proteins might mediate cisplatin genotoxicity but also should apply more generally in the

111 the role of PARP in suppression of bleomycin genotoxicity by integrins using wild-type and PARP knock

112 e than cellulose on ameliorating AOM-induced genotoxicity by up-regulating antioxidant enzyme genes,

113 Sam68 deleted cells are hypersensitive to genotoxicity caused by DNA damaging agents.

114 eted cells and animals are hypersensitive to genotoxicity caused by DNA-damaging agents.

115 mutation (SCID-X1) despite the occurrence of genotoxicity caused by the integration of first-generati

116 markers of defense and damage, biomarkers of genotoxicity (comet assay), and behavioral biomarkers (f

117 hlorination of wastewaters produced CHO cell genotoxicity comparable to chloramination, 3.9 times mor

118 Often overlooked in studies, genotoxicity could be dismissed for the investigated com

119 The molecular mechanisms (genotoxicity, cytotoxicity) were analyzed in vitro in no

120 significant correlations were observed among genotoxicity, cytotoxicity, and NAC thiol reactivity for

121 molecular genotoxicity assay is suitable for genotoxicity detection.

122 d DNA damage and oxidative stress, and their genotoxicity did not decrease as a function of irradiati

123 This enhancement of genotoxicity did not occur when the inactive C145A mutan

124 rbed by DMSe-derived SOA, including elevated genotoxicity, DNA damage, and p53-mediated stress respon

125 al, mammary and hair follicle epithelia that genotoxicity does not promote apoptosis but paradoxicall

126 s, which indicates that 4-MCHM is related to genotoxicity due to its DNA damage effect on human cells

127 retention mechanism to control A3A and avert genotoxicity during innate immune responses.

128 y that generated the lowest cytotoxicity and genotoxicity employed chlorination first followed by MPU

129 racts did not induce any toxic effects (cyto-genotoxicity, estrogenic or anti-androgenic activity) in

130 Interpretation of positive genotoxicity findings using the current in vitro testing

131 tic acids, and unregulated DBPs, and the SOS genotoxicity followed the breakthrough of dissolved orga

132 Most studies have not noted genotoxicity following AAV-mediated gene delivery; there

133 ) micronucleus assay attested high levels of genotoxicity following treatment of peripheral blood lym

134 rovides new insights into the requirement of genotoxicity for DMBA-induced immunosuppression in vivo

135 toxic, the total calculated cytotoxicity and genotoxicity for the GAC treated waters for the other tw

136 5.5-5.8) than at neutral pH, suggesting that genotoxicity from arylamine metabolism by NAT could be m

137 A concentration dependent genotoxicity has been found in nanomaterials.

138 for the first time and their effect on DNA (genotoxicity) has been investigated.

139 atients due to vector integration-associated genotoxicity have been observed.

140 lofuranones, and especially as regards their genotoxicity, here we report an in silico study of the a

141 are gaps in the database for dichloromethane genotoxicity (i.e., DNA adduct formation and gene mutati

142 s had the highest degree of cytotoxicity and genotoxicity (i.e., IC(50), SSBs and DSBs) after TG expo

143 ipid and protein oxidation and inhibition in genotoxicity in a dose-response manner.

144 es may induce genetic damage, but a role for genotoxicity in biphenyl-induced carcinogenicity has not

145 himurium, and chronic cytotoxicity and acute genotoxicity in Chinese hamster ovary (CHO) cells to com

146 Although the rank order was similar for genotoxicity in CHO cells and mutagenicity in S. typhimu

147 een benzene exposure and accepted markers of genotoxicity in humans.

148 Hs) are of significant interest due to their genotoxicity in humans.

149 air pathway counteracts acetaldehyde-induced genotoxicity in mice.

150 tagenicity of tamoxifen as a function of its genotoxicity in the cII transgene in Big Blue mouse embr

151 astly, both compounds 1r and 2r did not show genotoxicity in vitro and displayed high LD50 values in

152 ensive study of TiO(2) nanoparticles-induced genotoxicity in vivo in mice possibly caused by a second

153 To analyze hepatic genotoxicity in vivo, we transferred the fumarylacetoace

154 d at 1 and 3 years of age, were examined for genotoxicity, including centrosomal amplification, micro

155 possibility of unravelling the mechanisms of genotoxicity, including the repair of genetic damage, en

156 troviral vectors and found clear evidence of genotoxicity, indicated by numerous common integration s

157 ts of dietary ginger on oxidative stress and genotoxicity induced by streptozotocin (STZ) diabetic ra

158 Genotoxicity induced by these compounds was reduced by i

159 Genotoxicity-induced hair loss from chemotherapy and rad

160 How genotoxicity-induced HF injury is repaired remains uncle

161 amage to the colon, this study tests whether genotoxicity is elicited systemically by acute and chron

162 A mechanistic understanding of carcinogenic genotoxicity is necessary to determine consequences of c

163 additional advantage of TMB, beside its non-genotoxicity, is the electrochemical reduction property,

164 midazo[4,5-b]pyridine) and PhIP-5-sulfate (a genotoxicity marker) accumulated in liver tissue, indica

165 The objective of the study was to identify genotoxicity markers in cord blood cells from newborns e

166 leaf extract- and quercetin-induced in vitro genotoxicity may be the result of Topo II inhibition.

167 bes that are used to measure their cyto- and genotoxicity may lead to inaccurate readings.

168 ith the aim to reveal the distinct potential genotoxicity mechanisms among the different nanomaterial

169 , potentially be used for risk assessment of genotoxicity-mediated cancers.

170 Cytotoxicity (MTT test) and genotoxicity (micronuclei assay) were not detectable.

171 Fancc suppresses cross-linker-induced genotoxicity, modulates growth-inhibitory cytokine respo

172 tes rather than complete exhaust is used for genotoxicity/mutagenicity assessment, which may reduce t

173 TCE-associated renal genotoxicity occurs predominantly through glutathione S-

174 nergy to confer resistance to both cyto- and genotoxicities of NQO, whereas protection afforded by GS

175 ed to reactive intermediates that caused the genotoxicity of 1 in the Ames and mouse lymphoma L51784

176 FAPY adduct the prime candidate for both the genotoxicity of aflatoxin, because mammalian cells also

177 his isogenic cell line, we have revealed the genotoxicity of ambient oxygen.

178 dicals, play an important causal role in the genotoxicity of arsenical compounds in mammalian cells.

179 The genotoxicity of benzene has been investigated in dozens

180 e examined the role of cellular vitamin C in genotoxicity of carcinogenic chromium(VI) that requires

181 rochemical protocol for direct monitoring of genotoxicity of catecholics is described.

182 study, we assessed the mutagenicity and the genotoxicity of complete diesel exhaust compared to an o

183 analyze the mammalian cell cytotoxicity and genotoxicity of concentrated organic fractions from sour

184 of graft-versus-host disease (GVHD), but the genotoxicity of conditioning remains a substantial barri

185 Asc amplified genotoxicity of Cr(VI) by altering the spectrum of DNA d

186 active Cr(III), vitamin C contributes to the genotoxicity of Cr(VI) via a direct chemical modificatio

187 s were responsible for both mutagenicity and genotoxicity of Cr(VI).

188 The predicted cyto- and genotoxicity of DBPs was calculated using published pote

189 xpression modulates cellular response to the genotoxicity of DNA double-strand breaks.

190 Arsenic inhibits DNA repair and enhances the genotoxicity of DNA-damaging agents such as benzo[a]pyre

191 dentify and characterize enzymes involved in genotoxicity of drugs and pollutants.

192 not observe a significant difference in the genotoxicity of each risk group treatment modality despi

193 ations of the c-myc oncogene showed that the genotoxicity of estrogen via AID production was not limi

194 some breaks in the MLL locus and the overall genotoxicity of etoposide are dependent on topoisomerase

195 lts elucidate a mechanism underlying the low genotoxicity of foamy virus, identify a novel insulator,

196 aycoechea et al., identify aldehyde-mediated genotoxicity of hematopoietic stem cells as a cause for

197 DNA repair factors that protect against the genotoxicity of ICLs generated by trioxsalen/ultraviolet

198 nological platform for monitoring the direct genotoxicity of individual components in complex environ

199 oprotective effects on NHK by mitigating the genotoxicity of IR through epigenetic mechanisms.

200 We investigated changes in the toxicity and genotoxicity of PAH-contaminated soil from a former manu

201 locking element that significantly decreases genotoxicity of retroviral integration.

202 Also, hAGT did not enhance the genotoxicity of S-(2-haloethyl)glutathiones that mimic t

203 Here, we evaluated the genotoxicity of selected food products in Finland.

204 tch repair (MMR) strongly enhances cyto- and genotoxicity of several chemotherapeutic agents and envi

205 ining a pyridone are not responsible for the genotoxicity of the clb cluster.

206 nation and to determine the cytotoxicity and genotoxicity of the concentrated organic fractions from

207 Toxicity and genotoxicity of the residues from solvent extracts of th

208 hydrocarbons (PAHs), but it can increase the genotoxicity of the soil despite removal of the regulate

209 iol does not significantly contribute to the genotoxicity of the very potent carcinogen DB[a,l]P in h

210 Next to the acute toxicity, the genotoxicity of these compounds was investigated.

211 ombine to protect E. coli from the potential genotoxicity of this DNA adduct.

212 erturbations may be responsible for both the genotoxicity of this lesion and its ability to be recogn

213 To explore the mechanism of the lower genotoxicity of TOR, the formation of DNA adducts induce

214 We investigated the genotoxicity of UVA1 versus UVB in the overall genome an

215 The genotoxicity of zidovudine has been established in exper

216 ythroid MN assay is capable of screening for genotoxicity on BM in a physiologically reflective manne

217 lts from the HUSTLE protocol suggest minimal genotoxicity or carcinogenicity with long-term hydroxyur

218 nearly complete reaction lacking detectable genotoxicity or deleterious impact on stem cell function

219 alogues showed potentiation without inducing genotoxicity or phenotypic changes in a human embryonic

220 ma, or for other diseases that are driven by genotoxicity or the molecular response to oxidative stre

221 wards alterations that have occurred through genotoxicity or through epigenetic modifications.

222 ment resulted in an increase in toxicity and genotoxicity over the course of a treatment cycle, where

223 dy investigates TiO(2) nanoparticles-induced genotoxicity, oxidative DNA damage, and inflammation in

224 stress responses to oxidative stress (Nrf2), genotoxicity (p53) and inflammation (NF-kappaB) and the

225 he formation of unregulated DBPs with higher genotoxicity potencies.

226 To minimize any genotoxicity, precise activation of CRISPR-Cas9 in the t

227 imilar functions and similar carcinogenicity/genotoxicity profiles.

228 s with similar functions and carcinogenicity/genotoxicity profiles.

229 screening with a battery of DT40 mutants for genotoxicity profiling, we found that column treatment i

230 iolet irradiation, but not by other forms of genotoxicity, providing a novel mechanism for stress-med

231 In vitro toxicity studies for genotoxicity, reactive oxygen species formation, and cel

232 ward the structure-mutagenicity or structure-genotoxicity relationships have been undertaken.

233 epeats (LTRs) may have significantly reduced genotoxicity relative to the conventional retroviral vec

234 anaemia is probably due to aldehyde-mediated genotoxicity restricted to the HSPC pool.

235 ditional cytotoxicity (live/dead) assay, the genotoxicity results from the single cell array based as

236 In a umu genotoxicity screen, cytochrome P450 2W1 catalyzed the a

237 n macroscopic surfaces opens new avenues for genotoxicity screening and enabled the first use of pure

238 Arrays suitable for genotoxicity screening are reported that generate metabo

239 the potential to become a valuable tool for genotoxicity screening for chemical safety evaluation, a

240 A damage could serve as a basis for in vitro genotoxicity screening for new organic compounds.

241 thick DNA-polyion films used in voltammetric genotoxicity screening sensors showed that concentration

242 Genotoxicity screening sensors that measure DNA damage f

243 e and DNA-adduct formation rates relevant to genotoxicity screening.

244 n of ECL arrays for high-throughput in vitro genotoxicity screening.

245 the latter in vitro and was negative in the genotoxicity screens with a satisfactory oral safety pro

246 dependent inhibition and was negative in the genotoxicity screens with a satisfactory oral safety pro

247 genotoxic lesions that are missed by current genotoxicity screens.

248 bs at the base contain rapidly dividing, yet genotoxicity-sensitive transit-amplifying cells (TAC) th

249 Results show that the genotoxicity sensors can be used to estimate relative DN

250 ity to a panel of mammalian cells, showed no genotoxicity signals, and had low probability of drug-dr

251 available evidence from animal experiments, genotoxicity studies and clinico-epidemiological observa

252 ia and evaluated in various cytotoxicity and genotoxicity studies in human retinal pigment epithelium

253 Recent work employing genotoxicity studies suggests that National Institute fo

254 e use of a single cell array based assay for genotoxicity study of nanomaterials using normal human f

255 systemic oxidative stress, cytotoxicity, and genotoxicity (such as DNA damage).

256 ages that significantly induce cell death or genotoxicity surrounding its Bragg peak remains unclear.

257 o) activation of MeIQ with another bacterial genotoxicity system (Salmonella typhimurium umu).

258 Genotoxicity testing is critical for predicting adverse

259 The conventional genotoxicity testing methods are laborious, take time an

260 The regulatory requirements for genotoxicity testing rely on a battery of genotoxicity t

261 on of TGx-DDI for high-throughput cell-based genotoxicity testing using nCounter technology.

262 enabling new strategies for drug discovery, genotoxicity testing, and environmental health.

263 or genotoxicity testing rely on a battery of genotoxicity tests, which generally consist of bacterial

264 MNPs exhibited significantly higher genotoxicity than BMs and promoted the expression of Bax

265 malian cells, are likely more susceptible to genotoxicity than prokaryotes in the ecosystem when expo

266 Thus, TOR is likely to have lower genotoxicity than TAM.

267 e more sensitive (6-fold) to benzene-induced genotoxicity than the female NQO1+/+ mice.

268 gation but rather by initiating a cumulative genotoxicity that deregulated DNA synthesis.

269 nscriptase inhibitor exposures induced fetal genotoxicity that was persistent for 3 years.

270 esult in low-level protection from cyto- and genotoxicities, this protection is greatly enhanced by c

271 NAT2 genetic polymorphisms on metabolism and genotoxicity, tissue-specific expression and the elucida

272 In this study, we evaluated the genotoxicity to Chinese hamster ovary (CHO) cells induce

273 nd I(-) levels may yield organics with lower genotoxicity to CHO cells than chlorine-based disinfecti

274 ective HSC transduction, with no evidence of genotoxicity to date.

275 ed by dextran sulfate sodium administration, genotoxicity to peripheral leukocytes and erythroblasts

276 Furthermore, no aBL-induced genotoxicity to the vaginal epithelial cells was observe

277 Q) was tested for potential cytotoxicity and genotoxicity upon A549 lung cancer cells and Human Umbil

278 as well as their ability to induce cyto and genotoxicity upon interaction with biological systems by

279 The soil extract fractions were tested for genotoxicity using the DT40 chicken lymphocyte bioassay

280 rmine the biodistribution, toxickinetic, and genotoxicity variances in murine animals.

281 determine if mammalian cell cytotoxicity and genotoxicity varied in response to different chlorinatio

282 Genotoxicity was also observed in colon mucosa of mice g

283 ed from E faecalis-infected macrophages; its genotoxicity was assessed in human colon cancer (HCT116)

284 MTT assay and flow cytometry analysis, while genotoxicity was assessed in vitro by alkaline comet, DN

285 Finally, no major genotoxicity was associated with the gene editing proces

286 e cytotoxicity by incorporating MTT dye, and genotoxicity was evaluated with the micronuclei test.

287 A statistically significant increase in genotoxicity was measured in the unfractionated soil ext

288 Additionally, genotoxicity was measured using the SOS-Chromotest (dete

289 Moreover, this systemic genotoxicity was observed in mice with subclinical infla

290 Remarkably, the sertraline-induced genotoxicity was partially rescued by co-incubation with

291 HBQ-induced genotoxicity was shown as increased levels of 8-hydroxy-

292 els of peripheral leukocyte and erythroblast genotoxicity were also observed.

293 Predictive models of carcinogenicity and genotoxicity were built using a random forest classifier

294 Signatures of carcinogenicity and genotoxicity were compared with external sources, includ

295 orine, the lowest levels of cytotoxicity and genotoxicity were observed with MPUV radiation.

296 Cytostatic effects, including genotoxicity, were cell- and metal-dependent, apart from

297 ly tested for its capacity to confer reduced genotoxicity when restored by short-term oral transfer.

298 based approaches likely underestimate Cr(VI) genotoxicity when standard ATM-activating carcinogens ar

299 Insertional mutagenesis and genotoxicity, which usually manifest as hematopoietic ma

300 Both genotoxicity with and without metabolic activation and t