ライフサイエンスコーパス: genotype

1 Recall performance did not differ by genotype.

2 their biologic dam or a dam of the alternate genotype.

3 tibodies, irrespective of class II HLA DR-DQ genotype.

4 osts increased with irradiance but varied by genotype.

5 the circulating H1N1 to create a novel H2N2 genotype.

6 hailand, with genotype 3 being a predominant genotype.

7 gnificance for predictions of phenotype from genotype.

8 onal "transcriptotype" that differs from the genotype.

9 und deviations from this relationship across genotypes.

10 PI Z heterozygote and compound heterozygote genotypes.

11 proximal were also more closely related for genotypes.

12 to construct 3D protein models for 2b and 3a genotypes.

13 e fast and accurate identification of peanut genotypes.

14 phical origin or tuber flesh colour of these genotypes.

15 ly has non-uniform uncertainty in individual genotypes.

16 selection of stress-resilient and resistant genotypes.

17 calcium currents were unchanged between the genotypes.

18 rought and competition treatments on diverse genotypes.

19 and GII.4 Sydney [47%]) were the most common genotypes.

20 92% from low- to high-resolution of European genotypes.

21 te the salt tolerant from the salt sensitive genotypes.

22 e obtained 58 protease/reverse transcriptase genotypes.

23 and complex traits are assessed on the same genotypes.

24 the residual genotypes from G1P[8] to other genotypes.

25 increases the number of transformable wheat genotypes.

26 dicator of the C(4)-CAM-C(4) switches in all genotypes.

27 a key element conserved across multiple host genotypes.

28 HEV p239 antigen, and cross-react with other genotypes.

29 p.C282Y homozygotes identified in community genotyping.

30 hepatitis C were further tested for HCV RNA genotyping.

31 The majority had HCV genotype 1 (83%, n = 25), followed by genotype 4 (10%, n

32 e five conformational antigenic sites of the genotype 1 HEV p239 antigen, and cross-react with other

33 m 1021 patients with HCV infection (506 with genotype 1; 16 with genotype 2; 314 with genotype 3; 13

34 According to the sensorial analysis, genotype 108 showed the highest final score (82), which

35 101 and 248 nucleotide sequences of HCV NS3 genotypes 1a, 1b, 2b, and 3a, respectively, and translat

36 HCV infection (506 with genotype 1; 16 with genotype 2; 314 with genotype 3; 13 with genotype 4; 166

37 We genotyped 21 single-nucleotide polymorphisms associated

38 25), followed by genotype 4 (10%, n = 3) and genotype 3 (7%, n = 2).

39 in several regions, including Thailand, with genotype 3 being a predominant genotype.

40 , we established a protocol based on the HEV genotype 3 p6 (Kernow C-1) and the human hepatoma cell l

41 ith genotype 1; 16 with genotype 2; 314 with genotype 3; 13 with genotype 4; 166 with genotype 6) who

42 22 (79.6% vs. 76.1%, respectively), while CC genotype (3.8% vs. 4.4%) and C allele (20.4% vs. 23.9%)

43 carried rs755622 GG (63.1% vs. 56.7%) and CG genotypes (33.1% vs. 38.9%) and G allele of rs755622 (79

44 1% and 83.3%), with GII.4 being the dominant genotype (39.0% and 52.8%).

45 ad HCV genotype 1 (83%, n = 25), followed by genotype 4 (10%, n = 3) and genotype 3 (7%, n = 2).

46 ith genotype 2; 314 with genotype 3; 13 with genotype 4; 166 with genotype 6) who received 12 to 24 w

47 ith genotype 3; 13 with genotype 4; 166 with genotype 6) who received 12 to 24 weeks of daclatasvir p

48 re microbiota when compared with wild barley genotypes adapted to desert environments with a preferen

49 Current genomic HPV genotyping algorithms use a simple read-alignment and fi

50 alone or in combination with HPV16/18/31/33 genotyping also showed significantly increased sensitivi

51 posed of conspecifics that may vary in their genotypes, also influences social behavior, creating the

52 In contrast, mice with the genotype Amhr2-Cre Pten((fl/fl)) Kras(G12V/+) (G12V mice

53 Major genotypes among the 306 infection episodes identified we

54 but it remains difficult to comprehensively genotype an individual cell(1).

55 In previous studies, we genotyped an association panel of 508 inbred lines genot

56 Among the 13 genotypes analyzed, TW ranged from 73.75 to 79.83 kg/hL.

57 data to determine the impact of the APP/PS1 genotype and a Hfd on capillary stalling and CBF.

58 fected by the dihydrofolate reductase (DHFR) genotype and cord plasma creatinine.

59 s of the CNV and reversion to the progenitor genotype and drug susceptibility phenotype.

60 lity categories (defined by a combination of genotype and feeding regime).

61 ation to preserve the essential link between genotype and phenotype and discuss how cells and biomime

62 ical tools, and by access to vast amounts of genotype and phenotype data.

63 A gradient in genotype and phenotype distribution exists across Europe

64 subgroups exist that can be defined by their genotype and phenotype.

65 ean age 27 years) with classic Fabry disease genotype and/or phenotype, we performed unbiased quantit

66 infection of stomach with m1, s1m1, and s2m1 genotypes and development to peptic ulcer disease.

67 eration depends on the match between partner genotypes and increases as bacteria adapt to their local

68 e highlight the current relationship between genotypes and molecular imaging phenotypes.

69 rols of European ancestry) from databases of Genotypes and Phenotypes.

70 lysis showed significant differences between genotypes and pollination time as well, which demonstrat

71 , or that distinguished wild from cultivated genotypes and whose divergence may be a consequence of d

72 Subsequent genotyping and analysis of available whole-exome sequenc

73 RP on Chr17q22 (RP17) was delineated through genotyping and genome sequencing, leading to the identif

74 ds in body fluids enables early diagnostics, genotyping and personalized therapy, but is challenged b

75 a GG genotype than in individuals with a CC genotype, and heterozygous carriers had intermediate exp

76 onsuming, works for only limited species and genotypes, and causes unintended changes to the genome a

77 We analysed directly obtained and imputed genotypes, and followed-up associated loci in 1,459 Euro

78 When cytology, HPV16/18 and HPV16/18/31/33 genotyping, and the S5 classifier were compared to outco

79 tween the tumour microenvironment and tumour genotype are highlighted, providing important clues as t

80 responses to water-stress are shaped by host genotype are poorly understood.

81 l innovation, unconventional applications of genotyping array data have emerged to address more diver

82 This study presents an Africa-specific genotyping array, which enables investigators to identif

83 These unconventional outcomes of genotyping arrays include polygenic score, runs of homoz

84 g CNVs called from both exome sequencing and genotyping arrays.

85 nd warrant prospective investigation of APOE genotype as a biomarker for melanoma outcome and therape

86 formation on the antigenic differences among genotypes as measured by neutralization, which could gui

87 revealed large-scale intermixing of diverse genotypes, as well as thousands of SVs intersecting gene

88 infection, especially for those with the ACE genotype associated with high ACE level.

89 blood cells, because of the Duffy-null (CC) genotype at rs2814778 in the ACKR1 gene.

90 tic associations to TDF response between HBV genotypes B and C and lack of a single pattern of mutati

91 Different Hp genotypes bind Hb with different affinities, with Hp 2-2

92 VP4 [P] genotype binding specificities of rotaviruses and differ

93 apamycin extended life span in virtually all genotypes but through different genetic variants.

94 A genotype by condition interaction in left parahippocampu

95 In contrast to fitness traits, the amount of genotype by environment interaction is small.

96 At V2 there was a Genotype by Violence interaction, with higher FPS in the

97 Of the 21 false-positive samples genotyped by PANDAA, only 6 (29%) were identified as low

98 nd will greatly facilitate the dissection of genotype-by-environment interaction.

99 t in complex ways giving rise to substantial genotype-by-environment interactions (GxE).

100 Genotyping-by-Sequencing (GBS) was applied in a set of 5

101 de polymorphisms (SNPs) markers obtained via genotyping-by-sequencing (GBS).

102 me-calibrated phylogenomic analysis based on genotyping-by-sequencing data [6] of the 15 species of S

103 to three foliar diseases, and genotyped with genotyping-by-sequencing.

104 six agronomically important traits and from genotyping-by-sequencing.

105 a large number of missing or incorrect naive genotype calls, which can be improved by identifying sha

106 nships and to understand how factors such as genotype, cell type, local environment and external pert

107 served that individuals carrying HLA class I genotypes characterized by greater tapasin independence

108 In the present study, 50 bread wheat genotypes characterized for the zinc and iron content, t

109 ations could not have been identified with a genotyping chip.

110 together, the associations between the risk genotype, circulating PACAP, and somatic anxiety severit

111 ric, reproductive, and metabolic traits in a genotyped cohort of 893 PCOS cases (median and interquar

112 significantly lower in patients with the CT genotype compared to the CC genotype (P = 0.01).

113 or many NDD risk genes, we present phenotype-genotype correlations for seven risk genes (CTCF, HNRNPU

114 ound in three (8%) of those where a specific genotype could be identified.

115 content and higher bioactive response, these genotypes could be recommended for the further cultivati

116 where the RNA alleles do not scale with the genotype count.

117 sues from eight inbred parents and 12 hybrid genotypes, covering a spectrum of heterotic groups, gene

118 57BL/6 mice that persistently replicate HBV (genotype D, serotype ayw)-either from a transgene or aft

119 ch is more robust to the presence of missing genotype data and genotyping errors.

120 Integration of this dataset with genotype data from the largest PTSD genome-wide associat

121 ical-by-descent haplotype segments in phased genotype data.

122 ated whole-exome sequencing and whole-genome genotyping data to identify rare, pathogenic (P) or like

123 Haplogroups were inferred from genotyping data using HaploGrep.

124 C. neoformans from both epidemiological and genotyping data, and more recently from the biological p

125 udy of the Chromosome 1 TaCLPB in four wheat genotypes demonstrated unique patterns of the homoeologo

126 pinnings of EoE, highlighting 13 genes whose genotype-dependent expression expands our etiologic unde

127 ssive disorder (MDD): the former has a lower genotype-derived heritability that cannot be explained b

128 -transcription polymerase chain reaction and genotypes determined by subgenomic sequencing.

129 SVR year 1; however, in patients with TT/TT, genotype did not change during and after DAA treatment.

130 The 4 NPM1/FLT3-ITD genotypes differed significantly with regard to clinical

131 cute heat stress assays resolved per-colony (genotype) differences that may have been masked by accli

132 me sequencing data did not identify a strain genotype-disease severity correlation.

133 Geographical differences in genotype distribution were observed based on the rotavir

134 One determinate mustard genotype DJ-113 DT-3 revealed maximum NUTEFF.

135 Using a genotype-driven approach, we identified a disorder that

136 pectedly, Elite varieties exerted a stronger genotype effect on the rhizosphere microbiota when compa

137 to the presence of missing genotype data and genotyping errors.

138 which has 28 consanguineous marriages and 59 genotyped family members.

139 methods were used for classification of six genotypes (five varieties and a pair of clones), viz.

140 (deletion or insertion), size accuracy, and genotype for 1235 putative insertions and deletions samp

141 a 'clinically defined' diagnosis of FMD were genotyped for 18 single-nucleotide polymorphisms (SNPs)

142 01 subjects with good dietary adherence were genotyped for 95 single nucleotide polymorphisms (SNPs)

143 Patients were genotyped for rs4680, a single nucleotide polymorphism o

144 Genomic deoxyribonucleic acid was genotyped for the rs4680 SNP using realtime polymerase c

145 inding affinity across 145 HLA-A, -B, and -C genotypes for all SARS-CoV-2 peptides.

146 ZD4694, lumbar puncture, structural MRI, and genotyping for APOEepsilon4 (18)F-AZD4694 values were no

147 Genotyping for rs187238, rs352140, rs1360573, rs2521634,

148 3 years of age, and a shift in the residual genotypes from G1P[8] to other genotypes.

149 ults indicate that higher g(sn) may arise in genotypes from hotter climates via increased SD.

150 wild growing blackthorn (Prunus spinosa L.) genotypes from the slopes of Fruska Gora mountain in nor

151 The high yielding and fast cooking genotypes from this study can be targeted as parental ma

152 perspectives on how to bridge the phenotype-genotype gap.

153 ons in RPGR and quantify the contribution of genotype, genetic modifiers, and XCI to phenotypic sever

154 9 genotype) predominated over RSV A (all ON1 genotype) globally (69.0% versus 31.0%) and in all count

155 r ticagrelor was significantly higher in the genotyped group compared with the usual care group (30%

156 jor alleles (*2, *3, *17) via salivary swab (genotyped group) or no genotyping (usual care) to guide

157 ticated and 20 wild barley (Hordeum vulgare) genotypes grown in an agricultural soil under controlled

158 physical properties of fourteen pomegranate genotypes grown in the subtropical region of Florida.

159 e constructed in which 6 of the 8 alleles or genotypes (GT) of gO were analyzed in the backgrounds of

160 eturning CYP2C19 genotype results along with genotype-guided pharmacotherapy recommendations using a

161 Secondary outcomes included agreement to the genotype-guided recommendations.

162 genotypes were divided into two groups: five genotypes had digestibility in the range of 51.93-58.13%

163 However, FPS and genotype have not yet been examined during development.

164 selection and planting of resistant eucalypt genotypes have been the major strategies to manage the d

165 ring allelic forms of Hp, resulting in three genotypes: Homozygous Hp 1-1 and Hp 2-2, and heterozygou

166 and also dichotomised HP into HP1-containing genotypes (HP1-1 and HP2-1) and HP2-2 to evaluate the HP

167 we examined serum PACAP and associated PAC1R genotype in a cohort of males and females with a primary

168 The presence of the Beijing genotype in Bamako remains worrying, given its high tran

169 BMI) measurements from 1966 to 2019 and were genotyped in a longitudinal population-based health stud

170 million grain yield data points for 28 wheat genotypes in 16 locations in France, over 16 years of hi

171 Linking phenotypes to genotypes in F0 was hindered by the complex mosacism and

172 igher emergence over dry seeds of intolerant genotypes in the field.

173 Z heterozygotes and additional rare variant genotypes in the gene encoding alpha-1 antitrypsin, SERP

174 the possibility of congenitally transmitted genotypes in three of their infants.

175 quences due to the lack of representation by genotyping in a large number of self-reported Native Haw

176 associations between ADC metrics and glioma genotypes, including Bonferroni correction for multiple

177 increased by 57% (95% CI: 0.38, 0.79) in GG genotype individuals, but by 141% (95% CI: 1.03, 2.85) i

178 nical diagnoses measured in 58,838 unrelated genotyped individuals.

179 Interestingly, in several combinations of genotype/induction strength, bioderivatization had a pos

180 ents of African ancestry and high-risk APOL1 genotype infected with SARS-CoV-2 have emerged during th

181 The SZ genotype is also considered severe; yet, its effect on l

182 Here, we investigate whether the Duffy-null genotype is associated with the risk of infection using

183 of research, it remains unclear how the PTEN genotype is related to clinical outcomes.

184 Upfront tumour genotyping is now considered an essential step in guidin

185 Global Group in Chronic Heart Failure score, genotype, level of BB exposure, and BB propensity score.

186 n of DNA is usually impossible and phenotype-genotype maps are rarely obvious.

187 trial, and 302 entered the trial to receive genotype-matched therapy-including 14 that re-registered

188 All data, including the imputed genotype matrix used for GWAS, are easily downloadable v

189 dies but suggest that children carrying risk genotypes may be susceptible to respiratory consequences

190 risk (mean: 2,693 pg/ml) than for the other genotypes (mean: 2,317 pg/ml; p = 0.014), and patients w

191 mine the effect of smoking cessation in this genotype.Methods: We prospectively enrolled 166 related

192 genetic etiology in two cohorts using custom genotyping microarrays, large imputation reference panel

193 ne does not affect the murine b-wave in both genotypes, most likely because of chelating amino acids

194 enotype (n = 20, 26%), followed by the Ghana genotype (n = 16, 21%).

195 the Cameroon genotype was the most prevalent genotype (n = 20, 26%), followed by the Ghana genotype (

196 Among those who are genotype-negative, >40% normalize their ECG after detrai

197 y-applicable approach for inferring directed genotype networks from data, but also provide a unique i

198 f the antimicrobial resistant phenotypes and genotypes observed among the investigated E. coli isolat

199 Phenotype and genotype of both patient tumors and derived low-passage

200 hows a striking variability depending on the genotype of MuV.

201 Genotypes of 33 single nucleotide polymorphisms previous

202 tes from badgers tended to be similar to the genotypes of cattle in the same area, except in the Low

203 Analytic tools to produce multi-locus genotypes of hosts based on these SNP markers were combi

204 nization of these responses across different genotypes of M. inflexa, which may be related to genotyp

205 Genotypes of these hybrids were inferred in silico based

206 Through a genome-wide SNP genotyping of 736 C. arabica accessions, we analyzed the

207 assigned to prospective rapid point-of-care genotyping of CYP2C19 major alleles (*2, *3, *17) via sa

208 prevalence and associated impact of tryptase genotypes on anaphylaxis in humans.

209 f intake of cruciferous vegetables and GSTM1 genotypes on kidney disease in mice as well as in human

210 udy of respiratory syncytial virus-A (RSV A) genotype ON1 genetic variability and clinical severity i

211 allele frequencies projected from reference genotypes onto principal component coordinates.

212 had expression patterns unique to particular genotypes, or that distinguished wild from cultivated ge

213 Changes in genotypes over time were observed in all subjects.

214 differed significantly with NAT2 acetylator genotype (p < 0.0001).

215 ents with the CT genotype compared to the CC genotype (P = 0.01).

216 enotypic variability in apparently identical genotype perturbations, 2) low-throughput electrophysiol

217 This suggests that identifying genotype-phenotype association on a genome-wide scale ov

218 A trend of a genotype-phenotype association was revealed between the

219 MT-SCCALR learns genotype-phenotype associations of multiple tasks jointl

220 an inability to identify diagnosis-specific genotype-phenotype associations.

221 However, a true genotype-phenotype correlation for BICD2 has not been pe

222 Genotype-phenotype correlation studies were carried out

223 heterozygous states to better understand the genotype-phenotype correlations and incomplete penetranc

224 No clear genotype-phenotype correlations are found.

225 enter cohort of 59 COQ8A patients, including genotype-phenotype correlations, 3D-protein modeling, in

226 ing evolution requires detailed knowledge of genotype-phenotype maps; however, it can be a herculean

227 disease cohort reported to date, updates the genotype-phenotype model established for ABCA4 variants

228 cusing on identifying one diagnosis-specific genotype-phenotype pattern.

229 ownstream pathways provide hints of possible genotype-phenotype relationships to some of the most com

230 ing of the interactome networks that mediate genotype-phenotype relationships(1,2).

231 ene disorders provide insight, indeed direct genotype-phenotype relationships, into the biological fu

232 ordance rates between our platform and other genotyping platforms for the 69 successfully genotyped S

233 -in-means+/-SE: 2.1+/-0.7, P<0.002) and LQTS genotype-positive family members (87.5+/-7.4, difference

234 CI, 5.6-269.1; P<0.001) increased hazard in genotype-positive family members.

235 ndard ACMG and MYH7-ACMG guidelines, and HCM Genotype Predictor Score was used to provide a validated

236 RSV B (all BA9 genotype) predominated over RSV A (all ON1 genotype) glo

237 In our cohort, a homozygous c.2991+1655A>G genotype presented with a more severe phenotype.

238 typic variation is related to the climate of genotype provenance and whether phenotypic plasticity ma

239 mbination of ECG abnormalities with positive genotyping (QTc, 482+/-35 ms).

240 ype block, polymorphism among accessions and genotyping quality.

241 of crossover events have been identified by genotyping related family members.

242 al drought tolerance of certain pearl millet genotypes remains elusive.

243 from 2015 to 2017 constituted >= 35 distinct genotypes, representing high levels of genetic diversity

244 Genotyping required survival to and participation in the

245 y was to determine whether returning CYP2C19 genotype results along with genotype-guided pharmacother

246 and applicable in measuring enset diversity, genotyping, selection and potentially breeding.

247 To investigate the M. pneumoniae genotype shift and its impact on clinical presentations,

248 069705T allele compared with the rs2069705CC genotype showed a 50% (range, 20-100%) increased risk of

249 Furthermore, the TPH2 genotype showed a significant interaction with childhood

250 Forty-seven genotyped SLT patients (with Bartter, Gitelman or EAST S

251 genotyping platforms for the 69 successfully genotyped SNPs (>96%) and for the rare variants (>99%).

252 ildren with pathogenic germline mutations by genotyping somatic mutations shared between tumors and b

253 A genotype-specific approach for diagnosis and risk strati

254 ount of sucrose loss during storage revealed genotype-specific main driver genes and pathways charact

255 flow called the Standard Tools for Acroporid Genotyping (STAG).

256 otes, CASQ2 homozygote/compound heterozygote genotype status in probands was associated with a 3.2-fo

257 ation was revealed between the phenotype and genotype subgroups.

258 viral load was significantly correlated with genotyping success (P < 0.001); DBS samples with corresp

259 pression was higher in individuals with a GG genotype than in individuals with a CC genotype, and het

260 heterogeneity in the form of distinct clone genotypes that arise over time and across different tiss

261 ance of redundancy in terms of the number of genotypes that give rise to the same phenotype.

262 on, which represents a four-fold increase in genotyping throughput.

263 ression models for 43 human tissues from the Genotype-Tissue Expression (GTEx) Project.

264 The Genotype-Tissue Expression (GTEx) resource has provided

265 Genotype-Tissue Expression Project (GTEx) RNA-seq data w

266 ciation study approaches in defining a clear genotype to phenotype model.

267 al regulatory responses of these six ERalpha genotypes to a set of ER agonists showed that both steri

268 d-representation sequencing and marker-based genotyping to understand dispersal dynamics and to chara

269 d variation in disease severity and confound genotype-to-phenotype analyses.

270 tion alleles enabled genetic confirmation of genotype-to-phenotype associations.

271 haplotype frequencies and r(2) from diploid genotypes under Hardy-Weinberg Equilibrium.

272 Pacific acroporids can also be genotyped using a subset of the SNP loci and additional

273 Colonies were genotyped using nine microsatellite markers and > 9,000

274 7) via salivary swab (genotyped group) or no genotyping (usual care) to guide antiplatelet drug selec

275 these into amino acid sequences and used for genotype variation analysis, and also to construct 3D pr

276 Ten percent of subjects with the Pi*MZ genotype vs 4% of noncarriers had LSMs of 7.1 kPa or mor

277 data have also shown that DISC1 607 Phe/Phe genotype was associated with higher T. gondii antibody l

278 ificant decrease of the resistant CYP6P9a-RR genotype was observed after ten generations (chi(2) = 6.

279 Within Lineage 4, the Cameroon genotype was the most prevalent genotype (n = 20, 26%),

280 Distribution of HP CNV genotype was: HP1-1 n=132 (18.1%); HP2-1 n=342 (46.8%);

281 The distribution of CFB rs4151667 (L9H) genotypes was not significantly different in the AMD pat

282 Cytomegalovirus genotyping was performed to identify LET-resistance-asso

283 Genotyping was performed using the Affymetrix Axiom and

284 the utility of circulating tumor DNA (ctDNA) genotyping, we compare trial enrollment using ctDNA sequ

285 s of isolates within regions that varied for genotype were similar to groups from other regions, whic

286 vealed that the expression differences among genotypes were closely associated with their performance

287 At the end of in vitro digestion, the genotypes were divided into two groups: five genotypes h

288 Multiple genotypes were found in three (8%) of those where a spec

289 Soybean genotypes were grown in field conditions during two seas

290 stability of stigma position in the selected genotypes, whereas they were highly heterogeneous for ot

291 A sub-clade of the Cameroon genotype, which emerged ~22 years ago was likely to be i

292 lassification is accomplished using filtered genotypes while implementing a full mixed model to accou

293 d the association of apolipoprotein E (APOE) genotype with cerebrovascular disease (CVD) in a large n

294 ped an association panel of 508 inbred lines genotyped with a total of ~550,000 SNPs (Illumina 50 K S

295 and resistance to three foliar diseases, and genotyped with genotyping-by-sequencing.

296 Coupling pMEI genotypes with gene expression profiles, we identify pME

297 The study of Brazilian Conilon coffee genotypes with unknown chemical composition and sensory

298 , transplant physicians should discuss APOL1 genotyping with potential living kidney donors self-repo

299 nce regarding functional differences between genotypes within species and potential consequences for

300 ffers the possibility to further disentangle genotype x phenotype interactions.