ライフサイエンスコーパス: genotyping

1 lumina Multi-Ethnic Global chip was used for genotyping.

2 nd 168 in the efavirenz arm who consented to genotyping.

3 transcriptase polymerase chain reaction, and genotyping.

4 2 regions of the ribosomal gene for C. auris genotyping.

5 tions and highlight the need for reliable SV genotyping.

6 mising treatment efficacy compared to tissue genotyping.

7 p.C282Y homozygotes identified in community genotyping.

8 ndels in targeted genes that are detected by genotyping.

9 iated with cardiomyopathy is identified, TTR genotyping.

10 Positive samples underwent genotyping.

11 clopidogrel and to identify such patients by genotyping.

12 icipants provided oral rinse samples for HPV genotyping.

13 hepatitis C were further tested for HCV RNA genotyping.

14 gestive in the original GWAS with additional genotyping.

15 group of patients was available for tryptase genotyping.

16 n of the transcriptome and DNA methylome and genotyping.

17 Genotyping (128 SNPs barcode) and sequences of entire pa

18 rsex or males using either medium-throughput genotyping (31,811 SNPs) or whole-genome sequencing (WGS

19 sed the effectiveness of the MADCaP Array by genotyping 399 prostate cancer cases and 403 controls fr

20 dent chromosomes), followed by two stages of genotyping across 6668 individuals from multiple Finnish

21 Dense single nucleotide polymorphism (SNP) genotyping across the DDC locus on chromosome 7p12 was a

22 Current genomic HPV genotyping algorithms use a simple read-alignment and fi

23 ken using the single-nucleotide polymorphism genotyping allelic discrimination method.

24 Subsequent in situ genotyping allows us to map each phenotype distribution

25 alone or in combination with HPV16/18/31/33 genotyping also showed significantly increased sensitivi

26 thresholds, the MinION can achieve levels of genotyping analysis and phenotypic resistance prediction

27 HLA genotyping analysis revealed that each cell line was hom

28 Subsequent genotyping and analysis of available whole-exome sequenc

29 tter") that causes difficulties in automated genotyping and cross-laboratory comparisons.

30 go heritable risk is captured by array-based genotyping and deep imputation.

31 3,903 crop wild relatives in a massive-scale genotyping and diversity analysis.

32 cilitate the standardization of P. jirovecii genotyping and easy data exchanges across different labo

33 Blood samples were retrieved for CYP2D6 genotyping and endoxifen measurements by Amplichip (Roch

34 ividuals including a subset with genome-wide genotyping and exome sequencing.

35 nter operating rooms, and obtain genome-wide genotyping and gene expression measurements for a subset

36 RP on Chr17q22 (RP17) was delineated through genotyping and genome sequencing, leading to the identif

37 ected by different laboratories with diverse genotyping and imputation protocols.

38 After genotyping and imputation, we performed association mapp

39 Through direct genotyping and imputation, we tested almost 7 million ge

40 Through genotyping and informed breeding practices, the prevalen

41 udy, with baseline MRI, CSF biomarkers, APOE genotyping and neuropsychological evaluation.

42 ds in body fluids enables early diagnostics, genotyping and personalized therapy, but is challenged b

43 Genotyping and phenotyping of 186 apple accessions from

44 Advances in genotyping and phenotyping techniques have enabled the a

45 xisting challenges in cardiovascular disease genotyping and phenotyping that can be addressed by the

46 decisions toward resource allocation (e.g., genotyping and phenotyping) in order to maximize predict

47 platform to meet the growing demand for SMA genotyping and prognostics.

48 r delayed healing provided blood samples for genotyping and self-reported itch scores within 1 year o

49 Genotyping and sequencing are destructive, time- and lab

50 Advances in high-throughput genotyping and sequencing technologies during recent yea

51 challenges associated with ctDNA-based NSCLC genotyping and suggest a framework for the implementatio

52 Current guidelines universally recommend genotyping and support the use of ctDNA testing in certa

53 association between HLA typing or rs2856830 genotyping and survival, and to determine whether HLA ty

54 f a combination of high throughput SNP-based genotyping and whole-genome sequencing (WGS).

55 When cytology, HPV16/18- and HPV16/18/31/33-genotyping, and S5 at baseline were compared to outcomes

56 When cytology, HPV16/18 and HPV16/18/31/33 genotyping, and the S5 classifier were compared to outco

57 days of mechanical ventilation underwent HLA genotyping, and were followed for the development of sep

58 ding antimicrobial resistance (AMR), classic genotyping, and whole-genome sequencing results.

59 ibe and discuss recent developments in these genotyping approaches, with a particular focus on method

60 Here, we review several unconventional genotyping array analysis techniques that have been buil

61 ole-genome sequences and the other GWAS used genotyping array data from an additional 5849 individual

62 l innovation, unconventional applications of genotyping array data have emerged to address more diver

63 gh speed, low cost, and high throughput, the genotyping array has gained lasting applications in geno

64 med a genome-wide association study, using a genotyping array tailored specifically for transplantati

65 he Prostate (MADCaP) Network has developed a genotyping array that is optimized for African populatio

66 ression adjusted for age, assessment center, genotyping array, and population genetics substructure.

67 This study presents an Africa-specific genotyping array, which enables investigators to identif

68 tate cancer risk were revealed using a novel genotyping array.

69 nal ages) were assessed using a high density genotyping array.

70 centres) with a two-stage study design using genotyping arrays and exome sequencing.

71 These unconventional outcomes of genotyping arrays include polygenic score, runs of homoz

72 st genome-wide association studies have used genotyping arrays that are hindered by SNP ascertainment

73 Single-nucleotide polymorphism genotyping arrays were used to calculate the genomic ris

74 Associations between mLOY, detected by genotyping arrays, and blood cell counts were assessed b

75 ed on SNPs or microsatellites, obtained from genotyping arrays, whole genome sequencing and whole exo

76 g CNVs called from both exome sequencing and genotyping arrays.

77 nia and Michigan compared to a nested RT-PCR genotyping assay and the ISO 15216-1 rRT-PCR method for

78 The TaqMan(R) genotyping assay is a rapid, highly sensitive and specif

79 Described here is a rapid multiplex SMA dPCR genotyping assay run on a fully integrated dPCR instrume

80 gnosis-were typed for GM alleles by a TaqMan genotyping assay.

81 As shown herein by genotyping assays and high-throughput genome-wide sequen

82 The SNP TaqMan(R) genotyping assays developed in this work successfully id

83 Contemporary HPV genotyping assays only detect < 25% of all known HPV gen

84 g methylation and human papillomavirus (HPV) genotyping assays were performed on cervical cells from

85 Pyrosequencing methylation and HPV genotyping assays were performed on exfoliated cervical

86 Fifty-nine patients had tissue genotyping at first evidence of SCLC.

87 th high polygenic AAA risk, once the cost of genotyping becomes comparable with that of screening ult

88 a, and the United States, underwent tryptase genotyping by droplet digital PCR.

89 Genotyping by gp60 demonstrated infection with the same

90 oad and each type's amplicon copies prior to genotyping by NGS, thereby maximizing multiple-type sens

91 Here we have used genotyping by sequencing (GBS) to determine the genetic

92 This relatively rapid genotyping by sequencing approach proved to be successfu

93 targeted trees was uncovered utilizing GBS (Genotyping by Sequencing) platform.

94 by single-nucleotide polymorphism arrays and genotyping by sequencing, respectively.

95 s subjected to high-density genotyping using genotyping by sequencing.

96 triticina using restriction site associated genotyping by sequencing.

97 Ps in the assay is an ideal resource for SNP genotyping by targeted amplicon sequencing.

98 xt-generation sequencing marker approaches - genotyping-by-sequencing (GBS) and Diversity Array Techn

99 Progeny were genotyped using a genotyping-by-sequencing (GBS) approach and sequence rea

100 Using a genotyping-by-sequencing (GBS) approach, a total of 19,3

101 P, and genotypically characterized using the genotyping-by-sequencing (GBS) approach.

102 We employed genotyping-by-sequencing (GBS) to investigate how geogra

103 Genotyping-by-Sequencing (GBS) was applied in a set of 5

104 f plant genetic resources through paired-end genotyping-by-sequencing (GBS), particularly in the abse

105 notyped at more than 100,000 SNP markers via genotyping-by-sequencing (GBS).

106 nucleotide polymorphism (SNP) markers using Genotyping-By-Sequencing (GBS).

107 de polymorphisms (SNPs) markers obtained via genotyping-by-sequencing (GBS).

108 dense genetic map of M. fusca using tunable genotyping-by-sequencing (tGBS) approach.

109 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative t

110 me-calibrated phylogenomic analysis based on genotyping-by-sequencing data [6] of the 15 species of S

111 nce workflow that harnessed existing tilapia genotyping-by-sequencing studies, such as Double Digest

112 known) of thousands of samples produced with genotyping-by-sequencing technologies; therefore, it is

113 Genotyping-by-sequencing was used to generate maize germ

114 ingle nucleotide polymorphisms identified by Genotyping-by-Sequencing.

115 to three foliar diseases, and genotyped with genotyping-by-sequencing.

116 six agronomically important traits and from genotyping-by-sequencing.

117 Algorithms designed for bulk DNA genotyping cause significant data loss when used for sin

118 For HPV genotyping, cervical and anal samples were obtained at b

119 ations could not have been identified with a genotyping chip.

120 ctly from aligned de novo assemblies improve genotyping compared to graphs built from intermediate SV

121 analysis with single-cell transcriptomes and genotyping confirmed that genetic subclones mapped to di

122 virus outbreaks (including stool testing and genotyping), coordinate complaint and response activitie

123 use next-generation sequencing has decreased genotyping cost more than 100.000 fold in the last 20 ye

124 lant breeding programs with the reduction in genotyping costs.

125 scientific usage, with a recent increase in genotyping data as a necessary component of Short Popula

126 d 1392 controls and aggregated our data with genotyping data from >100 000 EUR and Asian RA patients

127 tive advantage to mutant clones, we analysed genotyping data from the blood-derived DNA of 482,789 pa

128 ogroup using single-nucleotide polymorphisms genotyping data in a DNA databank and extracted outcomes

129 ated whole-exome sequencing and whole-genome genotyping data to identify rare, pathogenic (P) or like

130 Here we use genome-wide high-density SNP genotyping data to investigate the taurine and indicine

131 Haplogroups were inferred from genotyping data using HaploGrep.

132 F.Measurements and Main Results: Genome-wide genotyping data were available for 1,699 individuals wit

133 Of the 804 PACG patients, genotyping data were available for 768 individuals and i

134 C. neoformans from both epidemiological and genotyping data, and more recently from the biological p

135 ily on very large amounts of phenotyping and genotyping data, presenting new challenges in effective

136 on while on maribavir, 23 had available UL97 genotyping data; 17 had known resistance mutations (T409

137 Fetal genotyping demonstrated that 70% of samples with HHV-6 R

138 the S5 classifier and cytology, whereas HPV genotyping did not provide additional information.

139 declined rapidly after the initial years of genotyping, documenting the benefit of a DNA screening p

140 encing technologies have reduced the cost of genotyping dramatically and led to genomic prediction be

141 nalyze 35 short tandem repeat (STR) loci for genotyping efficiency, and compare heterozygosity estima

142 chnological advances have enabled widespread genotyping efforts and dynamic research in the field of

143 substantially inflates the estimated rate of genotyping errors even in deeply sequenced genomes and e

144 to the presence of missing genotype data and genotyping errors.

145 f was identified through donor and recipient genotyping exhibited worse allograft survival (P=0.02).

146 for leveraging SV catalogs for short-read SV genotyping experiments.

147 ZD4694, lumbar puncture, structural MRI, and genotyping for APOEepsilon4 (18)F-AZD4694 values were no

148 However, routine clinical use of genotyping for CYP2C19 loss-of-function alleles in patie

149 marizes the evolving use and applications of genotyping for red cell and platelet blood group antigen

150 Genotyping for rs187238, rs352140, rs1360573, rs2521634,

151 Additional genotyping for the LRRTM4 region demonstrates an epistat

152 Genotyping for the PNPLA3 rs738409 genotype was undertak

153 Two factors make genotyping from single cells using single nucleotide pol

154 authors' key finding, however, was that MLVA genotyping grouped infections closely with associated ho

155 rmoglycemic individuals for whom genome-wide genotyping, gut metagenomic sequence and fecal short-cha

156 ctDNA genotyping has the potential to accelerate innovation in

157 domized controlled trial of clinical CYP2C19 genotyping implementation, pharmacogenetic test results

158 to determine whether HLA typing or rs2856830 genotyping improves risk stratification in clinical prac

159 es, 7,262 controls) and one with genome-wide genotyping imputed to the Haplotype Reference Consortium

160 zed by genome assembly and novel motif-based genotyping in 12 hypervariable HCMV genes.

161 rform whole-exome-sequencing and genome-wide genotyping in 145 patients (median age-at-diagnosis of 3

162 We performed Pneumocystis jirovecii genotyping in 5 outbreaks, which suggested that specific

163 quences due to the lack of representation by genotyping in a large number of self-reported Native Haw

164 the clinical impact of implementing CYP2C19 genotyping in a real-world setting is unknown.

165 APOL1 genotyping in donors with recent African ancestry is con

166 he association was confirmed through further genotyping in multiple broiler populations.

167 s might finally be able to utilize effective genotyping in nearly all patients with advanced-stage NS

168 es from our experience for considering APOL1 genotyping in the living donor evaluation.

169 However, achieving high precision genotyping in the single-cell environment is challenging

170 by validation of candidate polymorphisms by genotyping in three independent cohorts.

171 ase-control design and performed genome-wide genotyping in white Swiss HIV Cohort participants with n

172 ntibodies (mAbs) therapy resistance and BRAF genotyping is a relevant prognosis marker in patients wi

173 Accurate HPV genotyping is crucial in facilitating epidemiology studi

174 readily implemented MRI biomarker for glioma genotyping is currently lacking.

175 Human papillomavirus genotyping is important to study natural history and vac

176 RAS genotyping is mandatory to predict anti-EGFR monoclonal

177 Upfront tumour genotyping is now considered an essential step in guidin

178 ApoL1 genotyping is obtained routinely or selectively by 45%,

179 Widespread genotyping makes cassava a model for clonally propagated

180 hajii et al. propose LAVA, an alignment-free genotyping method which is able to more quickly genotype

181 een difficult to infer due to limitations in genotyping methodology.

182 rials, limitations inherent to the molecular genotyping methods have led some researchers to question

183 Agreement between genotyping methods was evaluated using Cohen's kappa coe

184 y validated variants without high-throughput genotyping methods.

185 tly reduced compared to those of traditional genotyping methods.

186 high-throughput genomic technologies is the genotyping microarray technology, which can genotype mil

187 genetic etiology in two cohorts using custom genotyping microarrays, large imputation reference panel

188 minimize the cost of sample preparation and genotyping, most genebank genomics studies in self-polli

189 We address the challenge of cost and genotyping multiple mutations using 203 porous three-dim

190 Genotyping (n = 230) identified one single-nucleotide po

191 Using a high-quality set of PCR-based genotyping of >200 loci, we show that TypeTE improves ge

192 s, men were offered a genetic test (based on genotyping of 33 risk-associated single nucleotide polym

193 CMV genetic diversity was determined by genotyping of 5 genes-gB (UL55), gH (UL75), gN (UL73), U

194 Through a genome-wide SNP genotyping of 736 C. arabica accessions, we analyzed the

195 The genotyping of 805 breast cancer tissues revealed a genot

196 r, that uses this method to perform targeted genotyping of a broad class of such loci.

197 Here, we show how in situ genotyping of a library of strains after time-lapse imag

198 Accurate genotyping of Alus and other mobile elements has been ch

199 Genotyping of amniotic fluid from each sac showed that t

200 Recent genotyping of an individual with severe epilepsy and Wil

201 mproving fruit flavor, we carried out target genotyping of and VOC extraction from a blueberry popula

202 However, genotyping of athletes to determine their dementia risk

203 t GangSTR, a novel algorithm for genome-wide genotyping of both short and expanded TRs.

204 Single-cell genotyping of circulating CD34 + progenitor cells allows

205 assigned to prospective rapid point-of-care genotyping of CYP2C19 major alleles (*2, *3, *17) via sa

206 ral variant detection focus on discovery and genotyping of deletions, insertions, and mobile elements

207 Accurate genotyping of DNA from a single cell is required for app

208 Automated genotyping of drug-resistant Mycobacterium tuberculosis

209 We performed retrospective high-resolution genotyping of HLA loci of 926 transplant pairs and used

210 The genotyping of hundreds of thousands of individuals has i

211 Genotyping of IL1RAP-related single nucleotide polymorph

212 Genotyping of LCT-13910 C/T (rs4988235) was performed to

213 Amp-Seq based genotyping of longitudinal samples improves detection of

214 e recruitment or retrieved from biobanks for genotyping of MC1R variants and ancestry informative mar

215 iplex gastrointestinal PCR panel followed by genotyping of norovirus- and rotavirus-positive samples.

216 35) and single-nucleotide polymorphism (SNP) genotyping of primary tumors (n = 914).

217 f of concept protocol for the sequencing and genotyping of Shiga toxin-producing Escherichia coli (ST

218 Full sequencing and genotyping of SNCA was performed in isolated/idiopathic

219 Genotyping of somatic cells as well as brain biopsies co

220 l sequencing of TMEM175/GAK/DGKQ followed by genotyping of specific associated variants was performed

221 int system and subsequently confirmed though genotyping of stool specimens.

222 equencing technology now allow comprehensive genotyping of the HLA region.

223 PCR genotyping of the produced offspring demonstrated three

224 mutation system (T-ARMS) PCR for qualitative genotyping of three LHON mtDNA mutations.

225 Genotyping of three patients with collapsing glomerulopa

226 To address this challenge, here we developed Genotyping of Transcriptomes (GoT), a method to integrat

227 However, genotyping of tumour biopsy samples is not feasible for

228 High-throughput genotyping offers the prospect of quick and repeatable e

229 The cohort was studied by classic genotyping or targeted next-generation sequencing (NGS).

230 In addition to ABCC4 genotyping, PEL phenotyping could open a new way toward

231 flexible or too restrictive results in poor genotyping performance.

232 that using these classes results in superior genotyping performance.

233 ordance rates between our platform and other genotyping platforms for the 69 successfully genotyped S

234 ment of array- and targeted sequencing-based genotyping platforms, coupled with rapid genome editing

235 h-quality samples, but when using the gSPIM, genotyping protocols could be more efficient by devoting

236 Current genotyping protocols devote the majority of resources to

237 mbination of ECG abnormalities with positive genotyping (QTc, 482+/-35 ms).

238 ype block, polymorphism among accessions and genotyping quality.

239 of crossover events have been identified by genotyping related family members.

240 Genotyping required survival to and participation in the

241 adult biological samples with data, such as genotyping results or confocal images, to enable robust

242 erence that would confound interpretation of genotyping results using microsatellite markers.

243 nsiderations for the interpretation of ctDNA genotyping results, which, particularly when using next-

244 Genotyping revealed a marked temporal cluster of P. falc

245 Genotyping revealed knockout efficiencies routinely grea

246 ma were also found in DBS, and replicate DBS genotyping revealed that a single test detected 86.7% of

247 Moreover, genotyping revealed that laboratory-cultured sporophytic

248 Genotyping rs12608932 resulted in 854 A/A, 988 A/C, and

249 and applicable in measuring enset diversity, genotyping, selection and potentially breeding.

250 thogenic variants in HCM in all populations; genotyping services should ensure coverage of this deep

251 Microsatellite genotyping showed relatively high P. vivax genetic diver

252 Single-cell transcriptomes with targeted genotyping showed similar skews in transcriptional primi

253 ctDNA genotyping significantly shortened the screening duratio

254 ere we introduce a new version of our repeat genotyping software, ExpansionHunter, that uses this met

255 ildren with pathogenic germline mutations by genotyping somatic mutations shared between tumors and b

256 flow called the Standard Tools for Acroporid Genotyping (STAG).

257 on method validation and limitations of the genotyping strategies.

258 -mer querying as well as the accuracy of the genotyping strategy.

259 viral load was significantly correlated with genotyping success (P < 0.001); DBS samples with corresp

260 -related outcomes, together with genome-wide genotyping supplemented with high-density imputation.

261 t in the NAGLU gene in Schipperke dogs and a genotyping survey in the breed.

262 any other psychiatric syndromes, advances in genotyping technology, allowing for inexpensive genome-w

263 opora hystrix were assessed at two scales by genotyping ten microsatellite markers for 356 individual

264 otyping was performed using the Linear Array genotyping test (Roche).

265 The genotyping test was assumed to cost the same as the Gene

266 However, we recommend rhAmp genotyping testing over HRM because of its enhanced sens

267 compares favorably with existing VL and HIV genotyping tests, proving an affordable option for combi

268 ctDNA testing offers accurate, rapid genotyping that enables the selection of mutation-direct

269 Genotyping the CYP6P9a-R resistance allele in oviposited

270 Genotyping these SVs in ~600 representative tomato acces

271 Most studies performed genotyping, though only 5 studies performed genome-wide

272 on, which represents a four-fold increase in genotyping throughput.

273 time, highlighting the importance of direct genotyping to assess their potential consequences and cl

274 lation-based case-control study coupled with genotyping to identify risk factors for sporadic cryptos

275 Genotyping to link lineage(s) to severity of cardiomyopa

276 MVP is conducting array-based genotyping to provide a genome-wide scan of the entire c

277 cytogenetic observations and high-throughput genotyping to quantify the levels of homoeologous recomb

278 d-representation sequencing and marker-based genotyping to understand dispersal dynamics and to chara

279 lecular inversion probes - a high-throughput genotyping tool.

280 with a reference genotype and the absence of genotyping tools specifically designed to detect noise f

281 plant material was subjected to high-density genotyping using genotyping by sequencing.

282 7) via salivary swab (genotyped group) or no genotyping (usual care) to guide antiplatelet drug selec

283 was quantified by qPCR, and rs2666433 (A/G) genotyping was performed by TaqMan Real-Time PCR.

284 Genotyping was performed by targeted next-generation seq

285 Genotyping was performed for 6 FLG mutations.

286 Genotyping was performed on DNA samples from beef-suckle

287 Cytomegalovirus genotyping was performed to identify LET-resistance-asso

288 Genotyping was performed using Taqman chemistry in real

289 Genotyping was performed using the Affymetrix Axiom and

290 d an automated DNA extraction method and HPV genotyping was performed using the Linear Array genotypi

291 Genotyping was successful for 50 of 79 LET subjects with

292 ion and single-nucleotide polymorphism (SNP) genotyping, we associated winter coat color polymorphism

293 the utility of circulating tumor DNA (ctDNA) genotyping, we compare trial enrollment using ctDNA sequ

294 te and accuracy, which are comparable to SNP genotyping, we suggest ensembleCNV holds significant pro

295 10 patients who were available for tryptase genotyping were all confirmed to have HalphaT.

296 Amp-Seq and length-polymorphism based genotyping were compared for their performance in follow

297 gh-resolution melting (HRM) and rhAmp(R) SNP genotyping - were developed to identify the beta-casein

298 Transcriptomes (GoT), a method to integrate genotyping with high-throughput droplet-based single-cel

299 Here, we combine molecular genotyping with network science and Bayesian inference t

300 , transplant physicians should discuss APOL1 genotyping with potential living kidney donors self-repo