ライフサイエンスコーパス: glomus

1 os fated to form its vascular structure, the glomus.

2 main protein, is expressed in the pronephric glomus.

3 phros, the tubules and the duct, but not the glomus.

4 ching of arbuscular mycorrhizal fungi of the Glomus and Gigaspora spp., and they promote rhizobial sy

5 the size-exclusion barrier of the glomerulus/glomus and recruit mesangial and endothelial cells to fo

6 mal morphogenesis and differentiation of the glomus and the convoluted renal tubules.

7 -anterior pronephros anlagen, permitting the glomus and tubules to develop in isolation.

8 , comprise a blood filter, the glomerulus or glomus, and an epithelial tubule that processes the filt

9 mour-1 gene, xWT1, a marker specific for the glomus at the stages analysed, together with other mesod

10 Unlike the pronephric tubules, the glomus can also be induced by FGF and RA.

11 metabolic model postulates that the rise in glomus cell [Ca2+]i, the initiating reaction in the sign

12 ntified acetate (which is known to affect CB glomus cell activity) as an agonist for the most highly

13 The molecular mechanisms underlying glomus cell acute oxygen (O(2)) sensing are unclear.

14 physiologically or pharmacologically induced glomus cell depolarization or hyperpolarization may not

15 cell RNA-Seq results characterized novel CB glomus cell genes, including members of the G protein-co

16 Carotid body growth and glomus cell hyperplasia, which was strongly induced in E

17 a2+]i seemed to play a significant a role in glomus cell intercellular communication.

18 7BL/6J) strain measuring the ventilatory and glomus cell intracellular calcium ([Ca(2+)](i)) response

19 s fully consistent with release of Ca2+ from glomus cell intracellular stores according to metabolic

20 in expression (Kv3.4 versus Kv4.3) in the CB glomus cell may contribute to the suppression of IK and

21 Accordingly, K(+) channel inhibition of the glomus cell membrane is expected to be followed by excit

22 s Ca2+-activated K+ (K+(Ca)) currents in the glomus cell of neonatal rat carotid body.

23 mutants exhibited impaired carotid body and glomus cell responses to H(2)S and breathing responses t

24 dult mice resulted in selective abolition of glomus cell responsiveness to acute hypoxia and the hypo

25 ex I (MCI) selectively abolishes the HVR and glomus cell responsiveness to hypoxia.

26 o proton pumping, fully recovers the HVR and glomus cell sensitivity to hypoxia in MCI-deficient mice

27 ial cytochrome c oxidase subunit, COX4I2, in glomus cell sensitivity to hypoxia.

28 h bilateral carotid body resections (BR) for glomus cell tumours.

29 gs and glomus cells was more complex, When a glomus cell was stimulated, current spread to the nerve

30 anifest impaired carotid body sensory nerve, glomus cell, and breathing responses to H(2)S and hypoxi

31 elease of an excitatory transmitter from the glomus cell, which is a secretory cell that is presynapt

32 forming next-generation sequencing on single glomus cell-derived cDNAs to eliminate contamination of

33 essed in glomus cells, which contained novel glomus cell-specific genes.

34 and resting potential (Em) of cultured mouse glomus cells (clustered and isolated) were simultaneousl

35 In the case of glomus cells (GC/GC coupling), it was mostly resistive a

36 osed of the neurotransmitter (NT)-containing glomus cells (GCs) and the sensory afferent fibers synap

37 ammasome and interleukin-1beta expression in glomus cells (p < 0.01).

38 e excitability of afferent nerve endings and glomus cells (putative chemoreceptor cells).

39 Short-term cultures of glomus cells (up to seven days), were employed to study

40 Release of transmitter from glomus cells activates the sensory afferent fibers to tr

41 Carotid body glomus cells also expressed IL-1 receptor and responded

42 Isolated carotid body glomus cells also sense glucose, and animal studies have

43 taneous stimulation and recording of coupled glomus cells and carotid nerve endings.

44 Glomus cells and carotid sinus afferents are anatomicall

45 uring Na2S2O4 occur by direct effects on the glomus cells and feedback action through released ACh an

46 -like immunoreactivity was localized to many glomus cells and nerve fibers and the concentration of S

47 2)S increased persulfidation in carotid body glomus cells and persulfidated cysteine(240) in Olfr78 p

48 stablished, the presence of TRPC channels in glomus cells and sensory nerves of the carotid body sugg

49 Glomus cells and sheath cells were immunocytochemically

50 rk, we quantify functional differences among glomus cells and show reciprocal sensitivity to acidosis

51 ly connected, and the chemical events in the glomus cells are expected to be conveyed reflexly as aff

52 To serve this role, carotid body glomus cells are highly sensitive to decreases in oxygen

53 Glomus cells are positive for G(Olf,) adenylate cyclase

54 Glomus cells are present in normal numbers and appear st

55 Carotid body glomus cells are the primary sites of chemotransduction

56 not affect the basal [Ca(2+) ]i in isolated glomus cells bathed in 5 mm KClo , but elicited transien

57 hus, hypoxia may suppress the K+ currents in glomus cells but K+ current suppression of itself does n

58 ate that this selective chemotransduction of glomus cells by either stimulus may result in the activa

59 und K(+) channels that mediate activation of glomus cells by hypoxia.

60 changes in arterial O(2) with activation of glomus cells by inhibition of unidentified background K(

61 est the redox inhibition of K(+) channels of glomus cells by reduced glutathione (GSH), dithiothreito

62 our results show that BK/Kv are activated as glomus cells depolarize in response to hypoxia, which th

63 from intracellular store in the carotid body glomus cells during hypoxia, we stimultaneously measured

64 lux both contribute to the depolarization of glomus cells during moderate to severe hypoxia.

65 o, 4-AP did not evoke any rise in [Ca2+]i in glomus cells either during normoxia and hypoxia, althoug

66 Chemosensitive carotid body glomus cells exhibited toll-like receptor (TLR-2 and TLR

67 Glomus cells express genes encoding HIF2alpha (Epas1) an

68 Cultured glomus cells expressed immunoreactivity for alpha3, alph

69 ng organ is the carotid body, which contains glomus cells expressing K(+) channels whose inhibition b

70 morphology and size of these cells resemble glomus cells found in amphibians, mammals, tortoises, an

71 ve O2-sensing cells were similar to those of glomus cells found in other vertebrates.

72 Experiments were performed on glomus cells from adult rat carotid bodies, rat pheochro

73 r normoxic conditions were blunted in the CB glomus cells from CHF rabbits compared with sham rabbits

74 tage-gated K+ (Kv) channels to hypoxia in CB glomus cells from CHF rabbits, and whether endogenous an

75 sensitivity of Kv channels to hypoxia in CB glomus cells from CHF rabbits; (2) high concentrations o

76 e NO donor SNAP (100 microm) increased IK in glomus cells from HF rabbits to a greater extent than th

77 results demonstrate that IK is reduced in CB glomus cells from HF rabbits.

78 Pairs of electrically coupled glomus cells from rat carotid bodies were impaled with m

79 Carotid body (CB) glomus cells from rat express a TASK-like background K+

80 of Ang II (> 1 nM) directly inhibit IK in CB glomus cells from sham and CHF rabbits; (3) changes in K

81 ker iberiotoxin (IbTx, 100 nm) reduced IK in glomus cells from sham rabbits, but had no effect on IK

82 the pH sensitivity of isolated carotid body glomus cells from young spontaneously hypertensive rats

83 Glomus cells had less negative Em and lower Ro.

84 Glomus cells harvested from Wistar rat carotid bodies we

85 Although carotid chemosensitive glomus cells have been the most extensively studied from

86 Glomus cells have mitochondria with specialized metaboli

87 we compared the outward K+ currents (IK) of glomus cells in sham rabbits with that in HF rabbits and

88 triggered by the activation of chemoreceptor glomus cells in the carotid body (CB) connected with the

89 ic basis of the marked oxygen sensitivity of glomus cells in the carotid body has long puzzled physio

90 Glomus cells in the carotid body respond to decreases in

91 hat while there is modest expansion of TH(+) glomus cells in the carotid body upon SDHC loss, PPGL is

92 sible for the oxygen-sensitive properties of glomus cells in the rat carotid body (CB) we used Ba2+,

93 [Ca2+]i in glomus cells increased in response to hypoxia (pO2 = 35

94 cular machinery and signalling pathway in CB glomus cells is still limited.

95 ody pH sensing by recording the responses of glomus cells isolated from rat carotid body to rapid cha

96 Carotid body (CB) glomus cells mediate acute oxygen sensing and the initia

97 ed cells and strings of cells, but clustered glomus cells never responded.

98 550 Torr) on the pHi and [Ca2+]i in cultured glomus cells of adult rat carotid body (CB) as a test of

99 IK was attenuated in glomus cells of HF rabbits, and their resting membrane p

100 g cells of fish (5HT) and those found in the glomus cells of mammals (acetylcholine, adenosine, and c

101 These results suggest that most glomus cells of the adult cat carotid body possess oxyge

102 The chemosensory glomus cells of the carotid body (CB) detect changes in

103 ialized for rapid functional oxygen sensing: glomus cells of the carotid body (peripheral respiratory

104 decrease in P(O2) (hypoxia) oxygen-sensitive glomus cells of the carotid body release ATP to activate

105 nd selectively expressed in oxygen-sensitive glomus cells of the carotid body, a chemosensory organ a

106 ia with a heterogenous pattern in individual glomus cells of the carotid body.

107 nd protein, which was primarily localized to glomus cells of the carotid body.

108 racterize the gap junctions between cultured glomus cells of the rat carotid body and to assess the e

109 enign neuroendocrine tumors derived from the glomus cells of the vegetative nervous system.

110 These results indicate that cultured cat glomus cells possess functional nAChRs, and that their c

111 heath cells and possibly a small fraction of glomus cells possess oxygen-insensitive potassium channe

112 Dual voltage clamping of coupled glomus cells showed a mean macrojunctional conductance (

113 Nicotinic AChRs of glomus cells showed high affinity for ACh.

114 Glomus cells survived MCIII dysfunction but showed selec

115 ensitive ion channels have been described in glomus cells that respond directly to extracellular acid

116 acidosis evoked transient inward current in glomus cells that was inhibited by the acid-sensing ion

117 creased outward potassium current (Ik) in CB glomus cells to levels similar to those that were observ

118 Ik was measured in glomus cells using conventional and perforated whole-cel

119 tinic ACh receptors (nAChRs) in cultured cat glomus cells using immunocytochemistry and whole cell pa

120 tracellular calcium ([Ca(2+)](i)) release in glomus cells via ryanodine receptor (RyR) activation by

121 Coupling between nerve endings and glomus cells was more complex, When a glomus cell was st

122 us to conclude that the redox modulation of glomus cells was not conveyed to the afferents, and this

123 ypoxic chemotransduction in the carotid body glomus cells was tested by using 4-aminopyridine (4-AP),

124 Glomus cells were identified by catecholamine fluorescen

125 Dissociated rat glomus cells were loaded with Fura-2 AM to study the eff

126 olarizing effect of low pH in SHR versus WKY glomus cells which was caused by overexpression of 2 aci

127 is a major arterial chemoreceptor containing glomus cells whose activities are regulated by changes i

128 of TASK by external acid, depolarization of glomus cells with high external KCl (20 mm) or opening o

129 current clamping after impaling two adjacent glomus cells with microelectrodes, and alternate stimula

130 (glomus cells, sheath cells, and subtypes of glomus cells) and oxygen sensitivity of potassium channe

131 formation between peripheral chemoreceptors (glomus cells) in the carotid body and relay neurons in t

132 he CB contains neurosecretory sensory cells (glomus cells), which release transmitters in response to

133 In carotid body chemosensitive glomus cells, activation of toll-like receptors increase

134 In carotid body glomus cells, AMPK is thought to link changes in arteria

135 In CHF glomus cells, an AT1 receptor (AT1R) antagonist, L-158 8

136 amniote respiratory reflexes - carotid body glomus cells, and 'pulmonary neuroendocrine cells' (PNEC

137 ar effects on cytosolic calcium ([Ca2+]i) in glomus cells, and if so, whether a heterogenous response

138 n experiments, induces calcium transients in glomus cells, and stimulates carotid sinus nerve activit

139 calcium currents accompany calcium inflow in glomus cells, but calcium influx may not depend exclusiv

140 v) are highly expressed in carotid body (CB) glomus cells, but their role in hypoxia-induced excitati

141 tissues most commonly studied, i.e. carotid glomus cells, central neurons, smooth muscle cells, and

142 lished the first transcriptome profile of CB glomus cells, highlighting genes with potential implicat

143 the most specifically expressed genes in CB glomus cells, highlighting their potential roles in mito

144 toplasmic Ca(2+) concentration in individual glomus cells, isolated in clusters from rat carotid bodi

145 etermine the correlation between cell types (glomus cells, sheath cells, and subtypes of glomus cells

146 ns have been implicated in oxygen sensing by glomus cells, the mechanism underlying their mitochondri

147 Glomus cells, the site of O2 sensing in the carotid body

148 Homology has been proposed between glomus cells, which are neural crest-derived, and the hy

149 ified a set of genes abundantly expressed in glomus cells, which contained novel glomus cell-specific

150 y a drop in intracellular pH of carotid body glomus cells, which inhibits a K+ current.

151 constant normoxic conditions in sham and CHF glomus cells, with threshold concentrations of about 900

152 sensitivity of IK and RMP to hypoxia in sham glomus cells.

153 ssion of Kv3.4 but not Kv4.3 channels in CHF glomus cells.

154 transmembrane Ca2+ influx into carotid body glomus cells.

155 geted to the plasma membrane in carotid body glomus cells.

156 TRPC proteins studied were present in type I glomus cells.

157 ent nerve terminals that encircle individual glomus cells.

158 ld by an inhibitor of Kv2, a major Kv in rat glomus cells.

159 of [Ca(2+)](i) and intercellular coupling in glomus cells.

160 by ratio fluorometry in isolated cat and rat glomus cells.

161 ings enveloped tyrosine hydroxylase-positive glomus cells.

162 g of the suppressant effect on K+ current of glomus cells.

163 tors modulate junctional conductance between glomus cells.

164 d variations in the response pattern between glomus cells.

165 ous response pattern similar to that seen in glomus cells.

166 for identifying highly expressed genes in CB glomus cells.

167 nt G protein-coupled receptor (Olfr78) in CB glomus cells.

168 s an approximately 20 pS channel in isolated glomus cells.

169 tion of hypoxia and acidosis at the level of glomus cells.

170 sensitivity to acidosis and hypoxia in most glomus cells.

171 ecular mechanisms of acute oxygen sensing by glomus cells.

172 3 (ASIC3) which we had identified earlier in glomus cells.

173 b) is present in approximately 74% of the CB glomus cells.

174 a did not change the Em of nerve endings and glomus cells.

175 d by hypoxia were greater in CHF versus sham glomus cells.

176 : (a) hypoxia increases cytosolic calcium in glomus cells; (b) response patterns were heterogeneous i

177 le similar to mammalian carotid body Type I (glomus) cells and pulmonary neuroepithelial cells.

178 ypertensive rats (SHRs) carotid body type I (glomus) cells exhibit hypersensitivity to chemosensory s

179 which contains neurosecretory chemoreceptor (glomus) cells innervated by sensory fibers whose activat

180 of O2 sensing by carotid body chemoreceptor (glomus) cells is that hypoxia inhibits the outward K(+)

181 Type I (also called glomus) cells, the site of O2 sensing in the carotid bod

182 Three populations of spores of Glomus claroideum (W2537) and three populations of spore

183 m (W2537) and three populations of spores of Glomus DAOM 225952 (W2538) were analysed using a microsa

184 retic types for G. claroideum, and 15-27 for Glomus DAOM 225952 depending on the population.

185 ands were found for G. claroideum, and 43 in Glomus DAOM 225952.

186 of G. claroideum, and none by populations of Glomus DAOM 225952.

187 tream of wt1 in the gene network controlling glomus differentiation.

188 However, when Glomus etunicatum was chosen as the outgroup, the polari

189 ils of conspecific plants, and feedback with Glomus etunicatum, a dominant mycorrhizal fungus.

190 rphic genetic markers in natural isolates of Glomus etunicatum, coupled with direct amplification of

191 irs of plants with and without the AM fungus Glomus hoi in microcosms that allowed only the fungus ac

192 he bacterial community responded to the AMF, Glomus hoi.

193 alysed the growth factor inducibility of the glomus in the presence or absence of retinoic acid (RA)

194 rmation by the arbuscular mycorrhizal fungus Glomus intraradices (Schenck & Smith) was limited to cor

195 h the symbiotic arbuscular mycorrhiza fungus Glomus intraradices and the rhizobial bacterium Sinorhiz

196 transformed carrot (Daucus carota) roots and Glomus intraradices grown monoxenically on bicompartment

197 pair of test plants, interlinked by a CMN of Glomus intraradices or Glomus mosseae.

198 ary from germinating spores of the AM fungus Glomus intraradices showed strong homology to gene seque

199 involved in the pathway were identified from Glomus intraradices, and for six of them the full-length

200 ired for infection by the mycorrhizal fungus Glomus intraradices, suggesting that LNP plays a role in

201 ated with the degree of root colonization by Glomus intraradices.

202 by which these fluxes occur in the AM fungus Glomus intraradices.

203 We show that the glomus is specified at stage 12.5, the same stage at whi

204 rsity of spores of two indigenous species of Glomus isolated from three soils of a long-term field ex

205 ascular approach to three patients harboring glomus jugulare paragangliomas.

206 ifficult to achieve complete obliteration of glomus jugulare tumors with the use of embolization and

207 t of the neoplasms are glomus tympanicum and glomus jugulare tumors.

208 HNPs, 26 were carotid body tumors (CBTs), 15 glomus jugulare, 3 glomus tympanicum, and 1 laryngeal pa

209 FAME profiles supported this hypothesis when Glomus leptotichum was used as the outgroup.

210 ards a mycorrhizal fungus closely related to Glomus macrocarpum.

211 tion, cobalt exerted a nonspecific effect on glomus membrane channels.

212 colonised and non-colonised by the AM fungus Glomus mosseae and five putative differentially regulate

213 second experiment, hyphae of both G. hoi and Glomus mosseae that exploited an organic material patch

214 terlinked by a CMN of Glomus intraradices or Glomus mosseae.

215 In this study effect of Glomus mosseae/Medicago sativa mycorrhiza on atrazine de

216 gan; each nephron consists of a single large glomus, one set of tubules and a single duct.

217 d lim1 which influences differentiation into glomus or tubule derivatives in vivo.

218 ient-absorbing hyphal surface over the genus Glomus prone to protection of soil organic C.

219 increase podocyte gene expression within the glomus proper.

220 e report a study on the specification of the glomus, the filtration device of the amphibian pronephri

221 er with high concentrations of RA can induce glomus tissue from animal cap ectoderm.

222 ions under which these growth factors induce glomus tissue in animal cap tissue.

223 s responsible for hereditary paragangliomas (glomus tumors, MIM No.

224 ereditary nonchromaffin paragangliomas (PGL; glomus tumors; MIM 168000) are mostly benign, slow-growi

225 Most of the neoplasms are glomus tympanicum and glomus jugulare tumors.

226 id body tumors (CBTs), 15 glomus jugulare, 3 glomus tympanicum, and 1 laryngeal paraganglioma.

227 icant increase in the abundance of the genus Glomus under heavy grazing.

228 ring the development of an AM symbiosis with Glomus versiforme and during growth under differing phos

229 the AM fungus Diversispora epigaea (formerly Glomus versiforme) and its MRE and performed comparative

230 onse to infection by the mycorrhizal fungus, Glomus versiforme.

231 esicular-arbuscular mycorrhizal (VAM) fungus Glomus versiforme.

232 eurospora crassa, and the mycorrhizal fungus Glomus versiforme.

233 la roots colonized by the mycorrhizal fungus Glomus versiforme.

234 n Glomeromycotina, and the most abundant VT, Glomus VTX00294, appeared in 87% of soil and root sample

235 etion of lmx1b results in the formation of a glomus with reduced size.