ライフサイエンスコーパス: glucocorticoid receptor

1 included endocrine-related end points ER and glucocorticoid receptor.

2 model with podocyte-specific deletion of the glucocorticoid receptor.

3 glomeruli through their interaction with the glucocorticoid receptor.

4 plication, implicating a membrane-associated glucocorticoid receptor.

5 CD8+- and CD4+-related host immunity via the glucocorticoid receptor.

6 o-express estrogen receptor alpha as well as glucocorticoid receptor.

7 is a crucial player for the stability of the glucocorticoid receptor.

8 ed to a significant elevation of hippocampal glucocorticoid receptors.

9 Glucocorticoids activate the glucocorticoid receptor, a ubiquitous nuclear receptor t

10 receptors (activated by epinephrine) and the glucocorticoid receptor (activated by corticosterone).

11 nd cocaine CPP in behaving rats both require glucocorticoid receptor activation during defeat episode

12 gulation of GILZ was neither associated with glucocorticoid receptor activation nor with transcriptio

13 uantified the dynamics of the cell cycle and glucocorticoid receptor activation, and explored their i

14 icated generally low estrogen, androgen, and glucocorticoid receptor activities, with 13 surface wate

15 ancer-site-specific phenotypes and increased glucocorticoid receptor activity in distant metastases.

16 ts as a co-chaperone that modulates not only glucocorticoid receptor activity in response to stressor

17 nt or interferes with estrogen, androgen, or glucocorticoid receptor activity.

18 Overall, these findings indicate that glucocorticoid receptor acts as an important regulator o

19 reatment with inhalation of the nonsteroidal glucocorticoid receptor agonist AZD5423 effectively redu

20 suggest that exogenous administration of the glucocorticoid receptor agonist dexamethasone-compared w

21 a (n = 297) before and after exposure to the glucocorticoid receptor agonist dexamethasone.

22 luated the effect of an inhaled nonsteroidal glucocorticoid receptor agonist, AZD5423, on allergen-in

23 We found that a synthetic glucocorticoid receptor agonist, dexamethasone, reduces

24 tor (GR), and could therefore be a selective glucocorticoid receptor agonistic modulator (SEGRAM).

25 mRNA levels of glucocorticoid receptor alpha and corticosteroid transac

26 lt-to-control asthma had significantly lower glucocorticoid receptor alpha levels at V0 (P = .05).

27 rthermore, the glomerular phosphorylation of glucocorticoid receptor and Akt, but not PPARgamma, corr

28 ered a novel protein interaction between the glucocorticoid receptor and beta-arrestin-1, a scaffold

29 ith the key orexigenic transcription factors glucocorticoid receptor and brain-specific homeobox fact

30 t signaling through heterologously expressed glucocorticoid receptor and degradation of a permanently

31 n regulating transcriptional activity of the glucocorticoid receptor and has multiple functions relat

32 Interestingly, the glucocorticoid receptor and its cofactors affect each ot

33 rgent DNA specificities, we examined how the glucocorticoid receptor and its paralogs evolved to bind

34 nal-dependent transcription factors, such as glucocorticoid receptor and nuclear factor kappa-b, on t

35 tectable plasma HIV-1 RNA), co-regulates the glucocorticoid receptor and PPARgamma and transduces hep

36 ivinA-induced upregulation of liver specific glucocorticoid receptor and Smad2/3 reporter constructs

37 red for alveolar fate specification; rather, glucocorticoid receptor and STAT3 work in parallel to pr

38 e mRNA expression of the beta variant of the glucocorticoid receptor and the 11-beta hydroxysteroid d

39 The glucocorticoid receptor and the mineralocorticoid recept

40 egulates the transcriptional activity of the glucocorticoid receptor and thereby promotes expression

41 CF, including PI3K/Akt-, Wnt/beta catenin-, glucocorticoid receptor-, and mTor signaling pathways.

42 otropin-releasing factor antagonists and the glucocorticoid receptor antagonist mifepristone, the HPT

43 Administration of a glucocorticoid receptor antagonist or DC-specific Tsc22d

44 Treatment of mutant mice with the glucocorticoid receptor antagonist RU486 restored KLF15

45 CORT125134 is a new selective glucocorticoid receptor antagonist under investigation.

46 icity after juvenile HFD are alleviated by a glucocorticoid receptor antagonist.

47 -3-one 3d (QCA-1093) as a novel nonsteroidal glucocorticoid receptor antagonist.

48 ted drugs, steroid synthesis inhibitors, and glucocorticoid receptor antagonists.

49 In all species, Sox9, Pax6, and the glucocorticoid receptor are expressed by Muller glia and

50 ous glucocorticoidogenesis and expression of glucocorticoid receptors are inhibited in psoriatic skin

51 progression results in the activation of the glucocorticoid receptor at distant metastatic sites, inc

52 the existence of crosstalk between LXA4 and glucocorticoid receptor at the cytosolic level mediated

53 o the molecular interaction between LXA4 and glucocorticoid receptor-based mechanisms.

54 intron functions as a genomic enhancer where glucocorticoid receptor binding regulates Kappa expressi

55 tually and synergistically enhancing p65 and glucocorticoid receptor binding to the IRAK-M promoter.

56 urine podocytes and enhanced the affinity of glucocorticoid receptor binding to the promoter region o

57 iption factor binding sites corresponding to glucocorticoid receptor binding.

58 Mechanistically, activated glucocorticoid receptor binds directly to a glucocortico

59 A disordered region at the N-terminus of the glucocorticoid receptor can fine tune how cells respond

60 Moreover, the transcription factors glucocorticoid receptor, CCAAT enhancer-binding protein

61 particular, Fkbp5 mRNA, which codes for the glucocorticoid receptor co-chaperone protein FKBP51, was

62 Moreover, glucocorticoid receptor cooperativity with factors, incl

63 Our data demonstrate that activated glucocorticoid receptor, decreasing aromatase expression

64 related to stress adaptation, including the glucocorticoid receptor (encoded by NR3C1).

65 Glucocorticoid receptor expression was attenuated in fib

66 ty, likely through modulation of hippocampal glucocorticoid receptor expression, an effect that is li

67 els of ERG, PTEN, androgen receptor PSA, and glucocorticoid receptor expression.

68 activity in transgenic plants bearing an ANT-glucocorticoid receptor fusion construct.

69 We also showed a loss of glucocorticoid receptor (GCR) in pro-inflammatory lympho

70 We also showed a loss of glucocorticoid receptor (GCR) in proinflammatory lymphoc

71 phosphorylation and function of the nuclear glucocorticoid receptor (GCR).

72 re we examine signatures of selection on the glucocorticoid receptor gene (Nr3c1) in African starling

73 effects of postnatal tactile stimulation on glucocorticoid receptor gene expression.

74 In mammals, methylation of the glucocorticoid receptor gene Nr3c1 has been implicated a

75 bition, demonstrating that Klf13 is a direct glucocorticoid receptor gene target.

76 of a neuron-specific exon 17 promoter of the glucocorticoid receptor (GR) (Nr3c1).

77 rovide insight into the molecular effects of glucocorticoid receptor (GR) activation at a clinically

78 investigations have examined the effects of glucocorticoid receptor (GR) activation prior to inflamm

79 Furthermore, glucocorticoid receptor (GR) activation repressed the li

80 istent with central HPA/I axis induction and glucocorticoid receptor (GR) activation, GR agonists enh

81 ve genomic and non-genomic processes through glucocorticoid receptor (GR) activation.

82 e identified the presence and bioactivity of glucocorticoid receptor (GR) active substances in water;

83 d in vitro estrogen (ER), androgen (AR), and glucocorticoid receptor (GR) activity, along with a broa

84 The glucocorticoid receptor (GR) agonist RU 28362 administer

85 eatment of human cells with dexamethasone, a glucocorticoid receptor (GR) agonist.

86 which activates transcription factors (TFs) glucocorticoid receptor (GR) and CREB within minutes and

87 ls through its molecular targeting of AR and glucocorticoid receptor (GR) and downstream pro-oxidant

88 The glucocorticoid receptor (GR) and KLF15 form a feed-forwa

89 meostasis through two nuclear receptors, the glucocorticoid receptor (GR) and mineralocorticoid recep

90 tion depends on the stress hormone-activated glucocorticoid receptor (GR) and neurotrophic factor rel

91 al expression of tyrosine hydroxylase (Th)], glucocorticoid receptor (GR) and plasma corticosterone,

92 Glucocorticoid receptor (GR) and STAT3 bind to the same

93 tes multiple nuclear receptors including the glucocorticoid receptor (GR) and the arginine rich N-ter

94 flammation and reduced both the level of the glucocorticoid receptor (GR) and the efficacy of dexamet

95 contributes to the functional status of the glucocorticoid receptor (GR) and to the quality of corti

96 The nonselective glucocorticoid receptor (GR) antagonist mifepristone has

97 Here, we demonstrated that the glucocorticoid receptor (GR) antagonist mifepristone red

98 e prevented when animals were treated with a glucocorticoid receptor (GR) antagonist RU486 during soc

99 Conversely, a glucocorticoid receptor (GR) antagonist significantly im

100 ithin this series, OP-3633 (15) emerged as a glucocorticoid receptor (GR) antagonist with increased s

101 tiinflammatory corticosteroids targeting the glucocorticoid receptor (GR) are the current standard of

102 tures to MIEs for androgen receptor (AR) and glucocorticoid receptor (GR) binding using ToxCast data.

103 The glucocorticoid receptor (GR) binds as a homodimer to gen

104 The glucocorticoid receptor (GR) binds the human genome at >

105 The glucocorticoid receptor (GR) binds the noncoding RNA Gas

106 roach reveal that Dex- but not CpdA-liganded glucocorticoid receptor (GR) binds to a single glucocort

107 Activation of the glucocorticoid receptor (GR) by the synthetic corticoste

108 The glucocorticoid receptor (GR) can tether to inflammatory

109 w that binding to nGREs is a property of the glucocorticoid receptor (GR) DNA-binding domain (DBD) no

110 Ligand-activated glucocorticoid receptor (GR) elicits variable glucocorti

111 haracterized by high levels of expression of glucocorticoid receptor (GR) encoded by NR3C1.

112 Here, we identified a gradient of increasing glucocorticoid receptor (GR) expression and signaling fr

113 ad reduced glucose transporter 1 (GLUT1) and glucocorticoid receptor (GR) expression in response to D

114 ng reduced progesterone receptor (PR) and/or glucocorticoid receptor (GR) expression or activity.

115 ave increased anxiety, decreased hippocampal glucocorticoid receptor (GR) expression, and increased h

116 t clinical need by genetic disruption of the glucocorticoid receptor (GR) gene using electroporation

117 lammatory transcription factors by monomeric glucocorticoid receptor (GR) has long been viewed as cen

118 xt, we showed that Ppid colocalized with the glucocorticoid receptor (GR) in BLA neurons and found th

119 ort that mice with selective deletion of the glucocorticoid receptor (GR) in DCs (GR(CD11c-cre)) were

120 ome-wide regulatory actions of ZNF764 on the glucocorticoid receptor (GR) in HeLa cells as a model sy

121 Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including t

122 te corticosteroid efficacy, interacting with glucocorticoid receptor (GR) in patients with chronic rh

123 dies revealed that Foxa3 is regulated by the glucocorticoid receptor (GR) in preadipocytes, adipocyte

124 To assess the role of the Glucocorticoid Receptor (GR) in such programming, we use

125 g frequencies via promiscuous binding to the glucocorticoid receptor (GR) in T cells.

126 antitatively explore the organization of the glucocorticoid receptor (GR) in the interphase nucleus o

127 ytoskeletal organization, interacts with the glucocorticoid receptor (GR) in the nucleus of human pod

128 relationship between the MR and the related glucocorticoid receptor (GR) in the response to cardiomy

129 The glucocorticoid receptor (GR) is a ligand-regulated trans

130 The glucocorticoid receptor (GR) is a ligand-regulated trans

131 The glucocorticoid receptor (GR) is a potent metabolic regul

132 The glucocorticoid receptor (GR) is essential for the stress

133 Given that glucocorticoid receptor (GR) is highly expressed in trip

134 The glucocorticoid receptor (GR) is the major receptor for t

135 Emerging data suggest that the glucocorticoid receptor (GR) is upregulated in this cont

136 The podocyte-specific glucocorticoid receptor (GR) knockout mice had similar r

137 ng studies revealed that PI3Ks act to reduce glucocorticoid receptor (GR) levels, which are rescued b

138 of inactive 11-dehydrocorticosterone to the glucocorticoid receptor (GR) ligand, corticosterone.

139 Because glucocorticoid receptor (GR) nuclear translocation is ke

140 Bmal1 regulated glucocorticoid receptor (GR) recruitment to the neutroph

141 The steroid hormone-activated glucocorticoid receptor (GR) regulates cellular stress p

142 This promoter contains two functional glucocorticoid receptor (GR) response elements (GREs) th

143 ted by dexamethasone because it contains two glucocorticoid receptor (GR) response elements (GREs).

144 The BoHV-1 genome contains approximately 100 glucocorticoid receptor (GR) response elements (GREs).

145 ition, pridopidine treatment upregulated the glucocorticoid receptor (GR) response, D1R-associated ge

146 Enhanced glucocorticoid receptor (GR) sensitivity is present in p

147 Noninvasive methods to study glucocorticoid receptor (GR) signaling are urgently need

148 By utilizing glucocorticoid receptor (GR) signaling as a model system

149 Glucocorticoid receptor (GR) signaling has recently been

150 regarding the actions of antidepressants on glucocorticoid receptor (GR) signalling.

151 In this study, we inactivated the glucocorticoid receptor (GR) specifically in kidney epit

152 le in vitro studies have demonstrated that a glucocorticoid receptor (GR) splice isoform, beta-isofor

153 m latency, in part because activation of the glucocorticoid receptor (GR) stimulates productive infec

154 with other steroid hormone receptors such as glucocorticoid receptor (GR) that plays a critical role

155 etic, and epigenetic research has linked the glucocorticoid receptor (GR) to memory processes, and to

156 s GW7647 and fenofibrate synergizes with the glucocorticoid receptor (GR) to promote BFU-E self-renew

157 steroids that are activating ligands for the glucocorticoid receptor (GR) transcription factor.

158 The genomic loci bound by the glucocorticoid receptor (GR), a hormone-activated transc

159 These drugs bind to the glucocorticoid receptor (GR), a ligand-activated transcr

160 The glucocorticoid receptor (GR), a nuclear receptor and maj

161 steroid levels, leading to activation of the glucocorticoid receptor (GR), a pioneer transcription fa

162 In contrast, the GFP-fused glucocorticoid receptor (GR), acting through the same HR

163 2) Glucocorticoid receptor (GR), an immunity-modulating tra

164 red indirect transrepression function of the glucocorticoid receptor (GR), and could therefore be a s

165 The estrogen receptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1

166 us levels of the androgen receptor (AR), the glucocorticoid receptor (GR), and the microRNA hsa-miR-2

167 oliferator-activated receptor gamma (PPARG), glucocorticoid receptor (GR), and thyroid hormone recept

168 our key TFs regulating the fasting response: glucocorticoid receptor (GR), cAMP responsive element bi

169 like transcription factor 15 (KLF15) and the glucocorticoid receptor (GR), cooperate to stimulate pro

170 atory molecules, and their cognate receptor, glucocorticoid receptor (GR), is expressed in nearly all

171 Dexamethasone (DEX), a synthetic ligand for glucocorticoid receptor (GR), is routinely used to stimu

172 g number of studies focused on the adipocyte glucocorticoid receptor (GR), its precise role in the mo

173 alpha (Esr1), estrogen receptor beta (Esr2), glucocorticoid receptor (Gr), mineralocorticoid receptor

174 ia corticosteroid-mediated activation of the glucocorticoid receptor (GR), stimulates viral gene expr

175 stimulates BC cell growth by binding to the glucocorticoid receptor (GR), the nuclear receptor of en

176 They bind to the Glucocorticoid Receptor (GR), which acts as a transcript

177 of an alternative nuclear hormone receptor, glucocorticoid receptor (GR), which has similar DNA-bind

178 tivation and repression, are mediated by the glucocorticoid receptor (GR), which is known to bind as

179 cocorticoids exert their effects through the glucocorticoid receptor (GR), which, upon glucocorticoid

180 cals, hormones, and estrogen-receptor (ER)-, glucocorticoid receptor (GR)-, and peroxisome proliferat

181 Glucocorticoid receptor (GR)-alpha phosphorylated at ser

182 of the endogenous anti-inflammatory pathway glucocorticoid receptor (GR)-annexin A1 (ANXA1) occurs.

183 Glucocorticoids (GCs)-ligands of the glucocorticoid receptor (GR)-are widely used to treat in

184 Using a glucocorticoid receptor (GR)-based fusion protein system

185 ypoxia response element (HRE) reporters in a glucocorticoid receptor (GR)-dependent manner.

186 ly reported that a nuclear receptor cofactor-glucocorticoid receptor (GR)-interacting protein (GRIP)1

187 It could enhance glucocorticoid receptor (GR)-luciferase activity and fac

188 Thus, although glucocorticoid receptor (GR)-mediated transactivation is

189 The mechanism involves a fetal glucocorticoid receptor (GR)-PPARalpha axis in which GR

190 in, and many of the factors contributing to, glucocorticoid receptor (GR)-regulated gene induction ar

191 Finally, we show that glucocorticoid receptor (GR)-regulated genes are signifi

192 characterize RNA synthesis from single-copy glucocorticoid receptor (GR)-regulated transcription sit

193 ss of androgen receptor (AR) blockade by the glucocorticoid receptor (GR).

194 HF is a weak endogenous agonist of the human glucocorticoid receptor (GR).

195 hosphate (FPP) and cortisol, ligands for the glucocorticoid receptor (GR).

196 optosis in lymphoid malignancies through the glucocorticoid receptor (GR).

197 tions of glucocorticoids are mediated by the glucocorticoid receptor (GR).

198 omain-containing protein Elk1 (Elk1) and the glucocorticoid receptor (GR).

199 anscription factor binding, including to the glucocorticoid receptor (GR).

200 the mouse uterus contains high levels of the glucocorticoid receptor (GR).

201 increased corticosteroid levels activate the glucocorticoid receptor (GR).

202 d direct podocyte protective effects via the glucocorticoid receptor (GR).

203 of the circadian clock and repressors of the glucocorticoid receptor (GR).

204 response element-binding protein (CREB), and glucocorticoid receptor (GR).

205 lucocorticoids (GCs) and their receptor, the glucocorticoid receptor (GR).

206 nflammatory compounds, which act through the glucocorticoid receptor (GR).

207 corticosteroids, which bind and activate the glucocorticoid receptor (GR).

208 Studies investigating Glucocorticoid Receptor (GR/NR3C1) in the brain have pri

209 Phosphorylation of the glucocorticoid receptor (GR:NR3C1) and activation of NR4

210 actor (BDNF) increase the desensitization of glucocorticoid receptors (GR) and vulnerability to stres

211 beta(2) adrenergic receptors (beta(2)AR) and glucocorticoid receptors (GR) are prescribed to treat pu

212 Phosphorylation of glucocorticoid receptors (GR) by brain-derived neurotrop

213 Glucocorticoid receptors (GR) have diverse functions rel

214 ene repression by transcription factors, and glucocorticoid receptors (GR) in particular, is a critic

215 levated circulating glucocorticoids (GC) and glucocorticoid receptors (GR) signaling impairment.

216 ical symptoms and variation in genes, NR3C1 (glucocorticoid receptor; GR) and NR3C2 (mineralocorticoi

217 hanisms underlying the opposing functions of glucocorticoid receptors (GRs) and estrogen receptor alp

218 Glucocorticoid receptors (GRs) are regulators of inflamm

219 ind to mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) in the hippocampus to reg

220 Using a novel strain of mice lacking glucocorticoid receptors (GRs) specifically in B cells,

221 ough interaction with ubiquitously expressed glucocorticoid receptors (GRs), this steroid hormone has

222 nalysis for the master regulator STAT5A, the glucocorticoid receptor, H3K27ac and MED1 identified 440

223 t in PFC of repeatedly stressed rats, active glucocorticoid receptor had the increased binding to the

224 onse may be a result of alterations in human glucocorticoid receptor (hGR) expression and function.

225 miR-433 can target the glucocorticoid receptor; however, glucocorticoid recepto

226 inter-regional variations relate to those in glucocorticoid receptor (HPA) and androgen receptor (HPG

227 and fear-circuit dysfunction, inflammation, glucocorticoid receptor hypersensitivity) in addition to

228 viors, as well as hyperactive fear circuits, glucocorticoid receptor hypersensitivity, and response t

229 Furthermore, chronic stress decreases glucocorticoid receptor immunoreactivity specifically in

230 bition is initiated by a membrane-associated glucocorticoid receptor in BLA principal neurons.

231 le for regulatory networks downstream of the glucocorticoid receptor in excessive alcohol drinking du

232 oietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, i

233 and phospho-proteomics studies implicate the glucocorticoid receptor in the activation of multiple pr

234 fferentially expressed genes targeted by the glucocorticoid receptor in the lung.

235 story we present began with the discovery of glucocorticoid receptors in hippocampus and has extended

236 he effect of tissue-specific manipulation of glucocorticoid receptors in mouse models of inflammation

237 or p25, up-regulation and phosphorylation of glucocorticoid receptors, increased HDAC2 expression, an

238 results indicate that the activation of the glucocorticoid receptor increases heterogeneity and meta

239 tic inhibition in BLA neurons via a membrane glucocorticoid receptor-induced release of 2-AG at GABA

240 Further, membrane glucocorticoid receptor influences glucocorticoid recept

241 ry we present an in silico simulation of the glucocorticoid receptor interaction network, linked to d

242 We conclude that the podocyte glucocorticoid receptor is important for limiting protei

243 ent evidence also demonstrates that membrane glucocorticoid receptor is present in numerous cell type

244 Thus, we generated adipose tissue-specific glucocorticoid receptor-knockout (Ad-GcR(-/-)) mice to e

245 Tamoxifen-inducible chondrocyte-targeted glucocorticoid receptor-knockout (chGRKO) mice were gene

246 inhibition of CASP1 significantly increased glucocorticoid receptor levels and mitigated glucocortic

247 and also by compound A, a novel nonsteroidal glucocorticoid receptor ligand.

248 lt skeletal muscle fibres, are mediated by a glucocorticoid receptor localised in the extracellular m

249 s regulating the HPA axis - particularly the glucocorticoid receptor - may facilitate adaptation to c

250 ling, we investigated the role of membranous glucocorticoid receptor (mbGR) by using cell-impermeable

251 er chronic stress may be caused by loss of a glucocorticoid receptor-mediated brake on interneuron ac

252 ntative cell line, as measured by changes in glucocorticoid receptor-mediated gene mRNA levels.

253 of the Cnr1 promoter and down-regulation of glucocorticoid-receptor-mediated expression of CNR1 in L

254 The glucocorticoid receptor mediates the effects of stress h

255 n both in vitro and in vivo, suggesting that glucocorticoid receptor might be a potential target for

256 (androgen receptor, estrogen receptor alpha, glucocorticoid receptor, mineralocorticoid receptor, and

257 reparing the nonsteroidal, inhaled selective glucocorticoid receptor modulator AZD7594.

258 nonsteroidal, selective indazole ether-based glucocorticoid receptor modulators (SGRMs) was developed

259 spring, including ones in white matter/glia, glucocorticoid receptors, neuroimmune outcomes, cerebrov

260 Recent findings in live cells show that the glucocorticoid receptor NR3C1 (also known as GR) forms t

261 of functional variants and haplotypes in the glucocorticoid receptor (NR3C1) and mineralocorticoid re

262 ignaling target HES1 expression was high and glucocorticoid receptor (NR3C1) low at the crypt base an

263 nd histone acetylation at genes encoding the glucocorticoid receptor (NR3C1), CNR1, and TRPV1.

264 The glucocorticoid receptor (NR3C1, also known as GR) binds

265 ted genes (FK506 binding protein 51 [FKBP5], glucocorticoid receptor [NR3C1], corticotropin-releasing

266 ger RNA in female rats was due to actions of glucocorticoid receptors on the orexin promoter, as dete

267 es have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many

268 in the expression of the beta variant of the glucocorticoid receptor or the 11-beta hydroxysteroid de

269 Driving minimal promoters with exogenous (glucocorticoid receptor) or synthetic transcription fact

270 First, S1PR1 regulates NFkappaB and nuclear glucocorticoid receptor pathways to suppress inflammatio

271 target the glucocorticoid receptor; however, glucocorticoid receptor protein abundance was unaffected

272 h, aiming to generate a Boolean model of the glucocorticoid receptor protein interaction network that

273 There were no effects on sperm count and glucocorticoid receptor protein levels within the epidid

274 ds can repress inflammatory gene expression, glucocorticoid receptor recruitment increases expression

275 ants in NR3C1 that alter the activity of the glucocorticoid receptor (rs56149945, rs41423247, and rs6

276 (Ser203, 211, and 226) located in the human glucocorticoid receptor's (GR's) ID AF1 domain.

277 Induction of glucocorticoid receptor signaling or forkhead box (FOXO)

278 tion changes, with activation of NK cell and glucocorticoid receptor signaling transcripts.

279 knockdown, we revealed a feedforward loop in glucocorticoid receptor signaling, previously unreported

280 ated cortisol stress, both of which activate glucocorticoid receptor signaling.

281 in osteoblasts by regulating sensitivity to glucocorticoid receptor signaling.

282 e signature reflecting adaptive immunity and glucocorticoid receptor signaling.

283 ng genes correspond to adaptive immunity and glucocorticoid receptor signaling.

284 through mitogen-activated protein kinase and glucocorticoid receptor signalling, respectively.

285 sulating more interactions/genes involved in glucocorticoid receptor signalling.

286 hat this core cluster is associated with the glucocorticoid receptor singling and neuroinflammation s

287 and synaptic function, immune signaling, and glucocorticoid receptor/stress response showed enrichmen

288 dentified Pik3r1 (also called p85alpha) as a glucocorticoid receptor target gene.

289 Although GCs have high affinity for the glucocorticoid receptor, they also bind and activate the

290 ith phosphorylated CREB and ligand-activated glucocorticoid receptor to directly control the inductio

291 Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D(3) and p

292 ry effect relies on the ability of activated glucocorticoid receptor to regulate the aromatase gene t

293 In light of its role in glucocorticoid receptor transactivation, we investigated

294 d nuclear receptor translocation, activating glucocorticoid receptor transcriptional targets.

295 membrane glucocorticoid receptor influences glucocorticoid receptor translocation to the nucleus eff

296 We demonstrate that human glucocorticoid receptor tunes this signaling in vivo by

297 entified the products of NR3C1 (encoding the glucocorticoid receptor), TXNIP (encoding a glucose-feed

298 Among these, the gene coding for the glucocorticoid receptor was independently identified as

299 The expression of CCR7 and of the glucocorticoid receptor was measured by using flow cytom

300 Antagonizing the glucocorticoid receptor with mifepristone (RU486) abroga