ライフサイエンスコーパス: glucosamine 6-phosphate

1 g glucose 6-phosphate, MondoA can also sense glucosamine 6-phosphate.

2 ulation of NagB and the metabolic fate(s) of glucosamine 6-phosphate.

3 ose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate.

4 anabolically were due to its activation with glucosamine 6-phosphate.

5 in the ubiquitous metabolites glycolate and glucosamine 6-phosphate.

6 nd catalyzes the deacetylation of N-acetyl-d-glucosamine-6-phosphate.

7 for endonucleolytic cleavage by the coenzyme glucosamine-6-phosphate.

8 tabolite-dependent ribozyme that responds to glucosamine-6-phosphate.

9 ated anabolically by physiological levels of glucosamine 6-phosphate (3 microm).

10 he glmS ribozyme, is adapted to an assay for glucosamine 6-phosphate, an effector molecule for the ap

11 In vitro, glucosamine 6-phosphate and glucose 6-phosphate stimulat

12 ructose 6-phosphate, generating the products glucosamine 6-phosphate and glutamic acid.

13 s of N-acetyl-d-glucosamine-6-phosphate to d-glucosamine-6-phosphate and acetate.

14 e wild-type enzyme, alone or in complex with glucosamine 6-phosphate, are also consistent with a hexa

15 n which fructose-6-phosphate is converted to glucosamine 6-phosphate by the rate-liming enzyme glutam

16 ccur by an acid-base mechanism involving the glucosamine-6-phosphate cofactor and G40 residue.

17 trate that oscillin is the mammalian form of glucosamine 6-phosphate deaminase by showing that cloned

18 hate and ammonia by the action of the enzyme glucosamine 6-phosphate deaminase, NagB.

19 Glucosamine-6-phosphate deaminase (GNPDA) catalyzes the

20 t analysis showed that the pellets contained glucosamine-6-phosphate deaminase (gpd)/oscillin, a prot

21 ), phosphofructokinase (PfkB, but not PfkA), glucosamine-6-phosphate deaminase (NagB), and adenylate

22 f the human testis 33 kDa protein produced a glucosamine-6-phosphate deaminase activity.

23 nsive amino acid identity with the bacterial glucosamine-6-phosphate deaminase enzyme.

24 The genomic structure of the human glucosamine-6-phosphate deaminase has been mapped and th

25 f the first member of this latter group, the glucosamine-6-phosphate deaminase, NagB, from Bacillus s

26 isplayed extensive homology with a bacterial glucosamine-6-phosphate deaminase.

27 ers: multimeric and allosterically regulated glucosamine-6-phosphate deaminases (exemplified by Esche

28 e synthase (GlmS) catalyzes the formation of glucosamine 6-phosphate from fructose 6-phosphate using

29 sitive assay that measures the production of glucosamine 6-phosphate (GlcN-6-P), purified recombinant

30 ith an early and rapid rise in the levels of glucosamine-6-phosphate (GlcN-6-P), a known activator of

31 ozyme in states before the activating sugar, glucosamine 6-phosphate (GlcN6P), has bound and after th

32 elf-cleaves at its 5'-end in the presence of glucosamine 6-phosphate (GlcN6P).

33 l change induced by binding of the cofactor, glucosamine 6-phosphate (GlcN6P).

34 By sensing the levels of the intermediate glucosamine-6-phosphate (GlcN6P) and self-adjusting the

35 The d-glucosamine-6-phosphate (GlcN6P) cofactor has been propo

36 Here taking the biosynthesis of glucosamine-6-phosphate (GlcN6P) in Bacillus subtilis as

37 olites of the hexosamine pathway, especially glucosamine-6-phosphate (GlcN6P) is unknown.

38 tive bacteria and is located upstream of the glucosamine-6-phosphate (GlcN6P) synthetase reading fram

39 Binding of glucosamine-6-phosphate (GlcN6P) uncovers the latent sel

40 al precursor of the bacterial cell envelope, glucosamine-6-phosphate (GlcN6P), is controlled by intri

41 The ribozyme is specifically activated by glucosamine-6-phosphate (GlcN6P), the metabolic product

42 The ribozyme is activated by glucosamine-6-phosphate (GlcN6P), which is the metabolic

43 th the assistance of the metabolite cofactor glucosamine-6-phosphate (GlcN6P), whose amino group is p

44 ositive bacteria are activated by binding to glucosamine-6-phosphate (GlcN6P).

45 Two analogues of glucosamine-6-phosphate (GlcN6P, 1) and five of glucosam

46 nd that by 48 h into encystment the level of glucosamine 6-phosphate has decreased to non-encysting l

47 hozoites are induced to encyst, the level of glucosamine 6-phosphate increases 3-fold over that of no

48 a tight-binding N-methylhydroxyphosphinyl-d-glucosamine-6-phosphate inhibitor were determined.

49 Glucosamine 6-phosphate is converted to fructose 6-phosp

50 N-Trifluoroacetyl-d-glucosamine-6-phosphate is hydrolyzed by NagA 26-fold fa

51 We investigated the expression of glucosamine-6-phosphate isomerase (Gln6PI), the first en

52 ed in the column format can detect 1 pmol of glucosamine 6-phosphate, much less than that required by

53 e provide genetic and chemical evidence that glucosamine 6-phosphate N-acetyltransferase (Gna1), a ke

54 It displayed no catalytic activity toward glucosamine 6-phosphate or N-acetylglucosamine 6-phospha

55 tes, including phenethylamine, agmatine, and glucosamine-6-phosphate (P < 0.05), while F affected the

56 ed region (UTR) of the glmS gene, binding of glucosamine-6-phosphate stimulates autocatalytic site-sp

57 ferases that includes asparagine synthetase, glucosamine 6-phosphate synthase, and glutamate synthase

58 residues resembles the glutaminase domain of glucosamine 6-phosphate synthase, another member of the

59 The amino-terminal cysteine of glucosamine-6-phosphate synthase (GlmS) acts as a nucleo

60 Glucosamine-6-phosphate synthase (GlmS) catalyzes the fo

61 rtion in glmS, encoding the essential enzyme glucosamine-6-phosphate synthase that catalyzes the firs

62 1680 protein encodes a universally conserved glucosamine-6-phosphate synthase.

63 ed ordered bi-bi mechanism, and performs the glucosamine-6-phosphate synthesis much more slowly than

64 Null mutations affected glucosamine-6-phosphate synthetase (glmS), which plays a

65 gC is relieved in the presence of N-acetyl-D-glucosamine-6-phosphate, the intracellular form of N-ace

66 The MMP1077 phosphomutase converted alpha-D-glucosamine-6-phosphate to alpha-D-glucosamine-1-phospha

67 NagA catalyzes the hydrolysis of N-acetyl-d-glucosamine-6-phosphate to d-glucosamine-6-phosphate and

68 eaminase (GNPDA) catalyzes the conversion of glucosamine-6-phosphate to fructose-6-phosphate, a react

69 re thus far that utilizes a small molecule - glucosamine-6-phosphate - to participate directly in rea

70 the hexameric form in the presence of cyclic glucosamine 6-phosphate, together with the decrease of t

71 detection limit of approximately 500 nM for glucosamine 6-phosphate under single-turnover conditions

72 nhibit the ability of bacteria to synthesize glucosamine-6-phosphate, which is required to build up t