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1 nts that synthesize phytoalexins from indole glucosinolate.
2 uts with enhanced levels of health-promoting glucosinolates.
3 yanates derived from nutritionally important glucosinolates.
4 localized elevation of indole and aliphatic glucosinolates.
5 dure for determination and quantification of glucosinolates.
6 no acid-derived secondary metabolites called glucosinolates.
7 vage also contributes to the biosynthesis of glucosinolates.
8 teps towards the biosynthesis of Met-derived glucosinolates.
9 pathways, such as the degradation of indole glucosinolates.
10 ses mainly epithionitriles and nitriles from glucosinolates.
11 vegetables containing high concentrations of glucosinolates.
12 glucosinolate genes, no increase in alkenyl glucosinolates.
13 terminants of side chain length in aliphatic glucosinolates.
14 the chain elongation pathway of Met-derived glucosinolates.
15 glucosinolate activation by forming desulfo-glucosinolates.
16 ne, as well as a differential composition of glucosinolates.
18 PCA allowed us to identify a big cluster of glucosinolates (10 out 15 tested) that do not possess an
19 at biosynthesis of 1-methoxyindol-3-ylmethyl glucosinolate (1MOI3M) from I3M involves the predicted u
20 table intermediate 1-hydroxyindol-3-ylmethyl glucosinolate (1OHI3M) and that IGMT5, a gene with moder
21 ignaling properties specific to one distinct glucosinolate, 3-hydroxypropylglucosinolate across plant
22 activation of myrosinase and preservation of glucosinolate (85% of the untreated level) was obtained
25 e-escalation in the numbers and diversity of glucosinolates, accompanied by an evolutionary increase
27 d on our results, we propose a model for how glucosinolates accumulate in the leaf margin and epiderm
28 absence of GTR1 and GTR2 transport activity, glucosinolates accumulate predominantly in leaf margins
29 he cngc19 mutants are deficient in aliphatic glucosinolate accumulation and hyperaccumulate its precu
33 a beetle (Psylliodes chrysocephala), prevent glucosinolate activation by forming desulfo-glucosinolat
34 mutational analysis identified residues for glucosinolate aglucone and Fe(2+) cofactor binding withi
35 an active site and docking arrangements with glucosinolate aglucones that may explain some of the dif
38 sms of defense metabolite signaling, we used glucosinolates, an important class of plant defense meta
39 mass spectrometry (LC-MS) was used to obtain glucosinolate and flavonol content for 35 rocket accessi
40 ce in B. juncea has facilitated selection of glucosinolate and lipid metabolism genes in subvarieties
41 fy industrial broccoli by-products for their glucosinolate and polyphenol contents as a first step to
44 this study was to determine the polyphenols, glucosinolates and ascorbic acid content as well as anti
45 n activating two-component defenses, such as glucosinolates and cyanogenic glycosides, occur in both
47 ysimum (Brassicaceae) produce both ancestral glucosinolates and evolutionarily novel cardenolides as
49 vironment conditions on the accumulations of glucosinolates and flavonols and explore the reasons for
53 oelements, their impact on the production of glucosinolates and phenolic acids and antioxidant proper
55 opsis thaliana) seeds, including benzoylated glucosinolates and substituted hydroxybenzoylcholines.
57 ried out on the influence of fermentation on glucosinolates and their degradation products from fresh
58 biological responses to structurally diverse glucosinolates and their transformation products, depend
59 were analyzed to determine their contents of glucosinolates and trace elements, and the bioaccessibil
61 ere dominated by changes in phenylpropanoid, glucosinolate, and fatty acid metabolism, although the n
62 enols (flavonolignans), macaenes, macamides, glucosinolates, and alkaloids) of maca (root and aerial
65 mostly acylated anthocyanins, five aliphatic glucosinolates, and four indolic glucosinolates as non-v
66 mutants increased their levels of camalexin, glucosinolates, and JA, and no long-term effects were ob
70 cosinolates decreased, suggesting that these glucosinolates are less involved in the plants' response
71 se findings provide deeper insights into how glucosinolates are metabolized in cruciferous plants and
76 ic acid signaling and biosynthesis of indole glucosinolates, are central to Arabidopsis's defense to
78 nd PcGSS2 used sinalbin and indol-3-ylmethyl glucosinolate as substrates, respectively, whereas PcGSS
80 Due to the instability of intact Moringa glucosinolates at room temperature and during the purifi
81 mutation in CYP83B1 and displays defects in glucosinolate biosynthesis and in phenylpropanoid accumu
82 part of a regulatory feed-back loop linking glucosinolate biosynthesis and JA signaling and thereby
85 t function in PAL degradation is affected in glucosinolate biosynthesis mutants and the disruption of
86 that IPMDH-like enzymes in both leucine and glucosinolate biosynthesis pathways use a common mechani
87 acids in the leucine- and methionine-derived glucosinolate biosynthesis pathways, respectively, in pl
88 gher expression of transcription factors for glucosinolate biosynthesis to improve its natural, healt
89 s-of-function mutations in genes involved in glucosinolate biosynthesis, a metabolically related rout
90 ormone signaling pathways, defense response, glucosinolate biosynthesis, cell wall modification, suga
96 ate promiscuity potentiated the evolution of glucosinolate biosynthetic enzymes, regulators, and tran
98 bidopsis thaliana) mutants for the essential glucosinolate biosynthetic gene ROOTY (RTY) that exhibit
99 een ER body-related genes (including PYK10), glucosinolate biosynthetic genes and the genes for so-ca
102 RT-PCR based expression analysis of seven glucosinolate biosynthetic pathway genes (MYB28, CYP79F1
104 While the toxic and deterrent effects of glucosinolate breakdown on herbivores and pathogens have
105 enables more detailed mechanistic studies on glucosinolate breakdown product formation, but also prov
108 ollowing secondary plant metabolites (SPMs): glucosinolate breakdown products, carotenoids, chlorophy
109 rimental investigations of the mechanisms of glucosinolate breakdown that will also help to better un
110 ced on cyp79B2 cyp79B3 hosts (without indole glucosinolates) but inhibited on atr1D hosts (with eleva
113 y studied the in vitro redox behaviour of 15 glucosinolates, by using a range of analytical methods m
114 er showed that triterpenoid biosynthetic and glucosinolate catabolic genes are up-regulated in jazQ i
116 ter specificity towards the recently evolved glucosinolates characteristic of Brassicales is shown to
117 ound weak to moderate phylogenetic signal in glucosinolate classes and no signal in total glucosinola
119 tegies toward the manipulation of beneficial glucosinolate compounds for animal health and plant prot
120 t of pressure level, temperature and time on glucosinolate concentration and myrosinase activity in B
121 s on residual myrosinase activity and intact glucosinolate concentration differed according to combin
122 ent CO2, leaf nitrogen had strong effects on glucosinolate concentrations and P. rapae consumption bu
125 The obtained beverages were characterized glucosinolates content at 117.6-167.6mg/L and ascorbic a
126 eatments could enhance effectively the total glucosinolates content in the sprouts, achieving the mos
127 of seeds as a novel strategy to trigger the glucosinolates content was carried out with water (contr
129 owed major reductions (81-84%) in the intact glucosinolate contents upon passage through the gastroin
132 criptomes of a suite of Arabidopsis thaliana glucosinolate-deficient mutants using RNAseq and identif
133 ely attributed to the biological activity of glucosinolate degradation products, such as sulforaphane
134 bbage versus neutral boiled blue cabbage) on glucosinolate degradation were investigated using UHPLC-
136 sugars, 9mg/mL amino acids, and 356microg/mL glucosinolates, depending on the type of by-product used
137 ts of L. sativum was especially rich in such glucosinolate derivatives as benzyl cyanide and benzyl t
138 he accumulation of pathogen-inducible indole glucosinolate-derived compounds, suggesting that PEN2 an
139 Here we investigated the molecular basis of glucosinolate desulfation in P. chrysocephala, an import
146 period and cold acclimatisation on levels of glucosinolates, fatty acids and soluble sugars in kale,
149 and activation of tryptophan-derived indole glucosinolates for subsequent PEN3-mediated efflux acros
152 ng hosts (wild type and atr1D) compared with glucosinolate-free hosts (cyp79B2 cyp79B3 myb28 myb29).
153 was actually reduced on dodder parasitizing glucosinolate-free hosts compared with wild-type or atr1
154 r, the desulfation step in the extraction of glucosinolates from Moringa oleifera leaves resulted in
156 ut microbiota have the ability to metabolize glucosinolates, generating chemopreventive isothiocyanat
157 d, despite an up-regulation of the aliphatic glucosinolate genes, no increase in alkenyl glucosinolat
160 ate the effect of storage on the contents of glucosinolates (GLS) and their degradation products in a
161 outs are well known for their high levels of glucosinolates (GLs), amino acids, and antioxidants, whi
162 lfur-rich cells (S-cells) accumulate >100 mM glucosinolates (GLS), but are biosynthetically inactive.
164 oncentrations of sensory relevant compounds: glucosinolates (GLSs), flavonoid glycosides, hydroxycinn
165 Decreasing contents were observed for the glucosinolates glucobrassicin and 4-methoxyglucobrassici
167 ected ITCs in the synovial fluid of the high glucosinolate group, but not the low glucosinolate group
170 three field trials, we quantified aliphatic glucosinolate (GSL) defense chemistry, leaf damage, and
172 he Arabidopsis thaliana defensive compounds, glucosinolates (GSL) control field fitness and are there
176 alibration to determine individual and total glucosinolates (GSLs) content of 12 new-bred open-pollin
177 opsis, accumulation of the defense compounds glucosinolates has previously been linked to genetic var
180 metabolites such as alkaloids, terpenes, and glucosinolates have been studied extensively, the fitnes
181 ontent, antioxidant activity and recoverable glucosinolates, however it increases the carotenoid conc
182 ygenase pathway (mainly C6-aldehydes) and of glucosinolate hydrolysis (mainly isothiocyanates), and t
183 utane, are important, but yet underestimated glucosinolate hydrolysis products that are released inst
186 iana) IG core biosynthesis, indol-3-ylmethyl glucosinolate (I3M), can be modified by hydroxylation an
187 (ER) body formation and induction of indole glucosinolate (IGs) metabolism selectively, via transcri
189 . thaliana root ER bodies, hydrolyzes indole glucosinolates (IGs) in addition to the previously repor
190 upled with the activity of putative vacuolar glucosinolate importers in these peripheral cell layers.
191 t proof of the existence of a 5-phenylpentyl glucosinolate in the aerial parts of this species as one
193 the breakdown products of sulfur-containing glucosinolates in cruciferous vegetables, have shown sub
195 relationship between accumulation of Se and glucosinolates in mature Brassica plants, Se supply gene
197 a higher production of methylsulphinylalkyl glucosinolates, including glucoraphanin, and, despite an
198 serpentine soil use; and that the number of glucosinolates increases with microhabitat bareness, whi
199 cabbage suggesting their non-involvement in glucosinolate induction during radiation processing.
200 jasmonates, signalling molecules involved in glucosinolate induction was, however, unaffected in irra
201 nd during the purification process of single glucosinolates, influences of different storage (room te
202 idence has revealed that the accumulation of glucosinolate intermediates limits phenylpropanoid produ
203 n elongation of methionine-derived aliphatic glucosinolates is catalyzed by methylthioalkylmalate syn
204 and acetyl-4-alpha-rhamnopyranosyloxy-benzyl glucosinolate isomers (Ac-Isomers-GS) during HPLC analys
205 vealed strong, positive correlations between glucosinolates, isothiocyanates and sulfur compounds wit
209 We detected a significant contribution of glucosinolate loci toward general herbivore resistance a
211 corbigen and methoxyl ascorbigen from indole glucosinolates) may serve as marker compounds for the in
212 rn may have led to the repeated evolution of glucosinolate metabolism and diversity in higher plants.
216 the terminal products of myrosinase-mediated glucosinolate metabolism, indicating that these systems
220 that can alter accumulation of the defensive glucosinolate metabolites in Arabidopsis (Arabidopsis th
221 bled detection of low concentrations (nM) of glucosinolate metabolites in human urine and plasma.
223 oach and a targeted approach for analysis of glucosinolate metabolites were developed using high reso
225 To date the common DIN extraction 'desulfo glucosinolates' method remains the common procedure for
227 nates, the bio-active hydrolysis products of glucosinolates, naturally produced by several Brassicace
228 related to Arabidopsis thaliana, synthesizes glucosinolates, nitrogen- and sulfur-containing secondar
229 450 monooxygenases and IGMTs encoding indole glucosinolate O-methyltransferases have been identified
231 rradiation also enhanced sinigrin, the major glucosinolate of cabbage that accounted for the enhanced
234 ced changes in secondary metabolites such as glucosinolates or flavonoids were detected in cml37 plan
235 n of BoMYB29 gene up-regulates the aliphatic glucosinolate pathway in Brassica oleracea plants increa
236 mutant plants remain partially sensitive to glucosinolate pathway mutations, suggesting that other m
241 s) are one of several hydrolysis products of glucosinolates, plant secondary metabolites that are sub
242 e, a dietary isothiocyanate derived from its glucosinolate precursor which is found in broccoli, can
248 educed significantly when dodder parasitized glucosinolate-producing hosts (wild type and atr1D) comp
249 glucosinolate classes and no signal in total glucosinolate production; a trend toward evolutionary de
250 ition to demonstrating the adaptive value of glucosinolate profile variation, we also detected long-d
251 36% of among accession variation in overall glucosinolate profile was explained by genetic different
252 emical foundation for the diversification of glucosinolate profiles across globally cultivated Brassi
254 erable variability in the total contents and glucosinolate profiles was observed in the Brassicaceae
255 ted phylogenetically explicit analyses using glucosinolate profiles, soil nutrient analyses, and micr
256 the genetics underlying natural variation in glucosinolate profiles, we conducted a large genome-wide
259 hibited on atr1D hosts (with elevated indole glucosinolates) relative to wild-type hosts, which respo
261 ed CO2 affected B. oleracea but not B. nigra glucosinolates; responses to soil fertility and damage w
262 stabilize 4-alpha-rhamnopyranosyloxy-benzyl glucosinolate (Rhamno-Benzyl-GS) and acetyl-4-alpha-rham
263 antioxidant capacity; while, the other five glucosinolates showed moderate and specific antioxidant
264 instead of isothiocyanates depending on the glucosinolate side chain structure and the type of speci
266 nary increase in the proportion of aliphatic glucosinolates; some support for the RAH relative to soi
267 showing a dramatic reduction of Met-derived glucosinolate species down to 32 and 14% of wild-type le
269 crude beetle protein extracts revealed that glucosinolate sulfatase (GSS) activity is associated wit
271 ication, on antioxidant capacity, phenolics, glucosinolates, sulphoraphane, Se-methyl selenocysteine
275 etic and biochemical basis for activation of glucosinolates to isothiocyanates by Bacteroides thetaio
276 aims at correlating the content of aliphatic glucosinolates to the expression of genes involved in th
278 s shared similar cardenolide traits, but not glucosinolate traits, likely as a result of specific sel
281 e association study of 22 methionine-derived glucosinolates using A. thaliana accessions from across
282 d not vary, while the response of individual glucosinolates varied with temperature and day length, a
284 a significant increase of total and specific glucosinolates, vitamin C, total anthocyanins and polyph
285 e, a method for extraction of intact Moringa glucosinolates was developed and no conversion and degra
290 acids, isoflavones, flavones, flavonols and glucosinolates were determined in fresh and fresh-cut sa
291 sformations of 2-hydroxyalkenyl and aromatic glucosinolates were examined in vitro under gastric cond
292 sses in the levels of phenolic compounds and glucosinolates were found in both extracts, considering
296 ominantly glucoraphanin (32-64% of the total glucosinolates), whereas the polyphenolic content was le
297 d Brassica species possess diverse aliphatic glucosinolates, which are important for plant defense an
298 logously expressed myrosinase were aliphatic glucosinolates, which were hydrolyzed with at least four
300 e breakage in cells harboring myrosinase and glucosinolate yields a brew toxic to many animals, espec