ライフサイエンスコーパス: glucosylation

1 ication within 2 h, as shown by differential glucosylation.

2 /beta peptide) blocked toxin A-mediated RhoA glucosylation.

3 mmed oligomerization following enzymatic a-d-glucosylation.

4 of the eight possible products of enzymatic glucosylation.

5 va, which is efficient at catalyzing B (1-2) glucosylation.

6 se variants in these proteins affect their O-glucosylation.

7 remote participation is used for a-selective glucosylation.

8 two distinct orientations as well as B (1-6) glucosylation.

9 but it is unknown if they are required for O-glucosylation.

10 sult of differences in OAg O-acetylation and glucosylation.

11 on inactivation of host small G-proteins by glucosylation.

12 residues in the reaction mechanism for self-glucosylation.

13 carbon nucleophile in this novel enzymatic C-glucosylation.

14 ding to substrates, independent of substrate glucosylation.

15 ycoproteins for transient, calcium-dependent glucosylation.

16 GNIP2 was shown to stimulate glycogenin self-glucosylation 3-4-fold.

17 either serine or asparagine eliminated self-glucosylation activity and reduced UDP-glucose hydrolyti

18 minated self-glucosylation and reduced trans-glucosylation activity by at least 260-fold but only red

19 le G433A/I434V mutation led to enhanced HDMF glucosylation activity compared to the wild-type enzymes

20 e recombinant yeast confirms the presence of glucosylation activity on sterol and hydroxy fatty acid

21 with k(cat) of 17 min(-1), but has very low glucosylation activity, < or = 0.3 min(-1), for an alter

22 ltransferase AriGT, indicate that reversible glucosylation acts as a self-resistance mechanism.

23 ased stability compared to 3 and position of glucosylation affected the stability of the xanthones wi

24 ns of these strains identified gtr-dependent glucosylation and acetylation.

25 elial T84 cells by mechanisms involving RhoA glucosylation and actin depolymerization.

26 Stabilization by glucosylation and activation by hydrolysis is essential

27 that pathogenic UGGT1 variants impair UGGT1 glucosylation and catalytic activity, disrupt mRNA splic

28 tionalized according to B-ring substitution, glucosylation and esterification.

29 Glucosylation and galactosylation of a panel of represen

30 of approximately 10 min(-1) for the first C-glucosylation and is distributive, with sequential conve

31 MAP kinase activation appears to precede Rho glucosylation and is required for IL-8 transcription and

32 either serine or asparagine eliminated self-glucosylation and reduced trans-glucosylation activity b

33 rvae revealed the defensive functions of the glucosylation and rhamnosylation steps in HGL-DTG biosyn

34 De(acetylation), glucosylation and sulfonation were the main metabolic pa

35 for compatibility with (i) serotype-specific glucosylations and O-acetylations defining S. flexneri O

36 rase (beta-GT)-mediated protection of 5-hmC (glucosylation) and recombinant mouse Tet1(mTet1)-mediate

37 n, confirming that it directly mediates Skp1 glucosylation, and NMR demonstrated formation of a Glcal

38 ty is regulated by both O-fucosylation and O-glucosylation, and Notch receptors contain multiple pred

39 ar domain of the receptor: O-fucosylation, O-glucosylation, and O-GlcNAcylation.

40 ble B (1-2) glucosylation, eliminate B (1-6) glucosylation, and obtain a promising catalyst for the i

41 herichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be

42 Rho glucosylation became evident after 15 minutes.

43 le pAGT activity by 95%, in vivo [(14)C]pABA glucosylation by 77%, and the endogenous pABA-Glc/pABA r

44 We reported previously the intramonomer glucosylation capability of glycogenin without determini

45 hanges arose specifically from the increased glucosylation caused by overexpression of 71B6.

46 Blocking O-glucosylation caused neonatal death with skeletal, pulmo

47 the synthesis genes, it possesses a prophage glucosylation cluster, which modifies the GlcNAc residue

48 n cellular ATP levels; cell rounding and Rho glucosylation commenced between 15 and 30 minutes.

49 flammasome by this toxin is dependent on Rho glucosylation, confirming similar findings reported for

50 Thereby, UGT76B1-mediated glucosylation controls the levels of active NHP, SA, and

51 lagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet the

52 In this study, we utilized glucosylation-deficient toxin A to show that activation

53 itination is conceptually reminiscent of the glucosylation-deglucosylation occurring in the ER lumen

54 this enzyme to enhance the desirable B (1-2) glucosylation, eliminate B (1-6) glucosylation, and obta

55 glycan relied on indirect methods comprising glucosylation followed by a multistep epimerization and

56 te oligomeric fragments using beta-selective glucosylation followed by gluco to manno epimerization a

57 7:1 ratio represents the published level of glucosylation for S. enteritidis LPS as well as for S. e

58 haracterization of a broad-specificity lipid glucosylation gene from C. bombicola, and the functional

59 plasm, and was eliminated by deletion of the glucosylation genes from the E. coli chromosome, restori

60 modified by cytosine hydroxymethylation and glucosylation (ghmC) exhibits various degrees of resista

61 To date, glucosylation has only been observed in O-antigens synth

62 arriers for bacteriophage-mediated O-antigen glucosylation in ABC transporter-dependent pathways.

63 hloroaniline (DCA) was rapidly detoxified by glucosylation in Arabidopsis thaliana root cultures, wit

64 The crtX gene was likely involved in C.p.450 glucosylation in Dietzia sp. CQ4.

65 the cytoplasm and catalyzed diterpene C19-O-glucosylation in planta.

66 mounts due to low levels of specific B (1-2) glucosylation in Stevia.

67 nderlies its flexibility to catalyze B (1-2) glucosylation in two distinct orientations as well as B

68 in glucosyltransferase catalysis impairs DNA glucosylation in vitro.

69 light the importance of POGLUT2/3-mediated O-glucosylation in vivo and open the possibility that O-gl

70 ingly, this palladium catalysis directs beta-glucosylations in the absence of classical neighboring g

71 Side chain glucosylation is a common modification strategy found in

72 Protein O-glucosylation is a conserved post-translational modifica

73 Enzymatic glucosylation is a strategy to reduce stevioside bittern

74 O-Glucosylation is stereo-specific: the O-glucosyltransfer

75 Possibly the initial glucosylation is via inter-dimeric catalysis with an int

76 ngly, only the serine (S) was required for O-glucosylation, leading to the revised consensus sequence

77 Self-glucosylation leads to the formation of an oligosacchari

78 sed a glycoproteomic approach by analyzing O-glucosylation levels of individual EGF repeats from over

79 ccines synthesized from OAg with the highest glucosylation levels, (ii) OAg composed of mixed- or med

80 Glucosylation modulates the biological activity of small

81 phila Notch receptor contain the consensus O-glucosylation motif.

82 glycan revealed that both O-acetylation and glucosylation occurred at the same C6 position on GlcNAc

83 These results indicate that the LH3-mediated glucosylation occurs at the specific molecular loci in t

84 Glucosylation of 17-HGL is therefore a critical step tha

85 UGT74P3 and UGT74P4 use UDP-glucose for the glucosylation of 17-hydroxygeranyllinalool (17-HGL) to l

86 two-step protocol that consists of enzymatic glucosylation of 5hmC with an azide-modified glucose, fo

87 e product of site-specific enzymatic alpha-d-glucosylation of a lightly protected non-natural disacch

88 Increased glucosylation of ABA led to phenotypic changes in post-g

89 The impact of increased glucosylation of ABA on ABA-related phenotypes has also

90 s a superior novel enzyme that catalyzes the glucosylation of allelopathic 3-hydroxy-alpha-damascone,

91 lycosyltransferase able to catalyze O-linked glucosylation of andrograpanin, yielding the major activ

92 Finally, we observed that glucosylation of both rhamnan and PSP can increase resis

93 al, we identified six UGTs that catalyze the glucosylation of C(13)-apocarotenols, where Glc is bound

94 Glucosylation of ceramide catalyzed by glucosylceramide

95 The results are a clear indication that O-glucosylation of cis-zeatin is a natural metabolic proce

96 ications, such as the hydroxymethylation and glucosylation of cytosine.

97 From this it was concluded that the glucosylation of DCA may not be as effective in xenobiot

98 hesis of the primer proceeds by intersubunit glucosylation of dimeric glycogenin, even though it has

99 lycones, signifying scaffold-selective C19-O-glucosylation of diterpenes in planta.

100 mber (ApUGT12/UGT86C11) that catalyzes C19-O-glucosylation of diterpenes with strict scaffold selecti

101 O-Glucosylation of epidermal growth factor-like (EGF) repe

102 tric analyses showed that R699 catalyzes the glucosylation of galactosylhydroxylysine to glucosylgala

103 GT73B24, UGT71W2, and UGT73B23 catalyzed the glucosylation of HDMF and its structural homolog 2(or 5)

104 to published information suggesting that the glucosylation of HPOs is a viable means of enhancing the

105 ement of ApUGT12 in scaffold-selective C19-O-glucosylation of labdane diterpenes in plants.

106 to achieve the demanding regioselective a-d-glucosylation of large substrates, paving the way to mic

107 dues, and glucose-P-dolichol (GPD)-dependent glucosylation of LLO.

108 The trans-glucosylation of maltose was reduced to undetectable lev

109 c Arabidopsis to determine whether increased glucosylation of monolignols could influence flux throug

110 n conveying them to distinct sites, and that glucosylation of monolignols is necessary for their vacu

111 Taken together, our results indicate that glucosylation of NAE 12:0 by a yet to be determined gluc

112 decrease in Rumi levels results in reduced O-glucosylation of Notch EGF repeats, and that the enzymat

113 iosynthesis in mycobacteria, and periplasmic glucosylation of O antigens first discovered in Salmonel

114 Increased glucosylation of other phenylpropanoids also occurred in

115 Stereospecific alpha-glucosylation of primary and secondary OH-group at carbo

116 230 and Tyr232 is necessary to suppress self-glucosylation of purified protein in vitro.

117 antibodies did not affect the TcdA-mediated glucosylation of Rac1 in RAW 264.7 cells, presaturation

118 ty in cultured mammalian cells by preventing glucosylation of Rho GTPases.

119 anoid metabolism and the important role that glucosylation of secondary metabolites can play in cellu

120 sules indicated that cpsF is responsible for glucosylation of serotype C capsular polysaccharide in E

121 We show that bacteriophage-encoded glucosylation of Shigella O antigen, the basis of differ

122 shRNA) directed against SLC11A1 reduced TcdB glucosylation of small Rho GTPases and, consequently, to

123 we present the optimized and efficient alpha-glucosylation of stevioside using the mutant glucansucra

124 The glucosylation of T4 phage DNA is part of a phage DNA pro

125 is is controlled by diverse means, including glucosylation of the bioactive BR brassinolide (BL), whi

126 the export of GspB glycoforms with increased glucosylation of the GlcNAc moieties.

127 widely in plant tissues, formed either by O-glucosylation of the hydroxylated side chain or N-glucos

128 etoxification occurs predominantly through O-glucosylation of the intermediate BOA-6-OH, most likely

129 559, are responsible for 'form variation' or glucosylation of the O12 antigen galactose (4 position)

130 sylation of the hydroxylated side chain or N-glucosylation of the purine ring structure.

131 lycosyltransferases (UGTs) that catalyze 3-O-glucosylation of the sapogenins oleanolic acid and heder

132 Resistance could be caused by glucosylation of the sapogenins.

133 catecholic siderophore enterobactin (Ent) by glucosylation of three aryl carbon atoms, a process cont

134 O-linked glucosylation of thymine in DNA (base J) is an important

135 We have recently demonstrated that O-linked glucosylation of thymine in trypanosome DNA (base J) reg

136 ansferases) in Fragaria that function in the glucosylation of volatile metabolites by comprehensive b

137 main of TpeL modifies Ras in vitro by mono-O-glucosylation or mono-O-GlcNAcylation.

138 to detect six reaction products of enzymatic glucosylation out of the eight possible ones.

139 ly, genes encoding enzymes involved in the O-glucosylation pathway have been cloned.

140 achieved for a pentasaccharide featuring the glucosylation pattern from the S. flexneri type IV O-ant

141 evaluated to reach a larger repertoire of O-glucosylation patterns encountered among S. flexneri typ

142 Here we describe a technique termed GLIB (glucosylation, periodate oxidation and biotinylation), w

143 The first approach, termed GLIB (glucosylation, periodate oxidation, biotinylation) uses

144 exploited a heterologous system to study the glucosylation potential of a model O-antigen produced in

145 Thus, LPS glucosylation promotes bacterial invasion and evasion of

146 se that has been suggested to have a role in glucosylation reactions related to the quality control o

147 o reduce stevioside bitterness, but reported glucosylation reactions suffer from low productivities.

148 nt SE6-E21 is identical to the high level of glucosylation reported for S. typhi LPS.

149 4-O-Glucosylation significantly stabilised 1 against degrada

150 e carried out a mutational analysis of these glucosylation sites and determined their effects on Notc

151 This variation may extend the glucosylation spectrum to Ras proteins, as observed prev

152 e a revision of the consensus sequence for O-glucosylation to allow alanine N-terminal to cysteine 2:

153 signaling, but the contribution of protein O-glucosylation to mammalian Notch signaling and embryonic

154 ed glycogenin produced by dimer intrasubunit glucosylation was 16% of that produced by the monomer.

155 he MSAE produced by heterodimer intersubunit glucosylation was 60% of that produced by the wild-type

156 expressing nonacetylated GspB with increased glucosylation were significantly reduced in their abilit

157 induce moderate-to-high alpha-selectivity in glucosylation with l-menthol with the best being 6-O-p-n

158 s 6-O-acyl groups on anomeric selectivity in glucosylations with thioglycoside donors was conducted.