ライフサイエンスコーパス: glucuronic acid

1 polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

2 UDP-glycosyltransferase UGT co-substrate UDP-glucuronic acid.

3 sulfate to the iduronic acid but not to the glucuronic acid.

4 fated heparosan, a polysaccharide containing glucuronic acid.

5 DP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.

6 ansformed cells on minimal medium containing glucuronic acid.

7 h as hormones by reversible conjugation with glucuronic acid.

8 se, d-glucose, d-arabinose, d-rhamnose and d-glucuronic acid.

9 rface, which selectively oxidizes glucose to glucuronic acid.

10 daily diet and environment by conjugation to glucuronic acid.

11 a salt bridge with the carboxylate group of glucuronic acid.

12 s two oxidations of UDP-glucose to yield UDP-glucuronic acid.

13 position 6 with glucuronic acid or rhamnosyl glucuronic acid.

14 d environmental chemicals via conjugation to glucuronic acid.

15 mediate that is synthesized by ArnA from UDP-glucuronic acid.

16 neurotoxic bilirubin by conjugating it with glucuronic acid.

17 a pathway for l-Ara4N biosynthesis from UDP-glucuronic acid.

18 e polysaccharide contained galactosamine and glucuronic acid.

19 the related IAG sequence, where G is alpha-D-glucuronic acid.

20 inked mannan substituted with D-xylose and D-glucuronic acid.

21 e HA or any other molecules known to contain glucuronic acid.

22 e hydroxyl groups in glycosidic linkage with glucuronic acid.

23 lycyrrhizin (GL) by hydrolysing one terminal glucuronic acid.

24 cid, rhamnose, mannose, xylose and traces of glucuronic acid.

25 ha-D-glucose, beta-D-glucose, rhamnose and D-glucuronic acid.

26 applied to develop a synthesis of protected glucuronic acid 1, a key intermediate in the synthesis o

27 ed a rare sequence consisting of consecutive glucuronic acid 2-O-sulfate residues as selectively targ

28 ies against carbohydrate epitopes, including glucuronic acid 3-SO4 and chondroitins 6-SO4 and 4-SO4.

29 tive cleavage of myo-inositol (MI) to give d-glucuronic acid, a committed step in MI catabolism.

30 doreductase that converts UDP-glucose to UDP-glucuronic acid, a key component of specific proteoglyca

31 gh content of the nonsulfated disaccharide D-glucuronic acid-acetylated glucosamine (GlcA-GlcNAc).

32 metabolites (methylated and conjugated with glucuronic acid) across hCMEC/D3 cells (a blood-brain ba

33 inant UAS homologs all form UDP-Api from UDP-glucuronic acid albeit in different amounts.

34 Mutations in a previously identified UDP-glucuronic acid allosteric binding site decreased the bi

35 nd glycolipid, termed Gl-X (mannose-alpha1-4-glucuronic acid-alpha1-diacylglycerol), which function a

36 We found that depletion of UDP-glucuronic acid altered the expression of PPAR-gamma tar

37 s for the sugar donors UDP-galactose and UDP-glucuronic acid, although UDP-glucose was always preferr

38 des UDP-glucose dehydrogenase which produces glucuronic acid, an essential component for the synthesi

39 ssive oxidations of UDP-glucose to yield UDP-glucuronic acid, an essential precursor for matrix polys

40 DP-glucose dehydrogenase (Ugd) generates UDP-glucuronic acid, an important precursor for the producti

41 shown to hydrolyze terminal alpha-1,2-linked glucuronic acid and 4-O-methylated glucuronic acid from

42 backbone of xylosyl residues substituted by glucuronic acid and 4-O-methylglucuronic acid (collectiv

43 that although wild-type xylans contain both glucuronic acid and 4-O-methylglucuronic acid residues,

44 ranosiduronic acids (glucuronides) using UDP-glucuronic acid and acceptor substrates such as drugs, s

45 lation, we identified O-acetylation of alpha-glucuronic acid and alpha-glucose in 9A PS.

46 utations in UXS1 lead to accumulation of UDP-glucuronic acid and alterations in nucleotide metabolism

47 es with low ratios of xylose to 4-O-methyl-D-glucuronic acid and appears to require two 4-O-methyl-D-

48 in itself, and this binding was inhibited by glucuronic acid and chondroitin sulfate.

49 hesized in the assay was composed of Glc and glucuronic acid and could be degraded to a low molecular

50 dependent oxidation of the 4''-OH of the UDP-glucuronic acid and decarboxylation of the UDP-4-keto-gl

51 f acidic O-linked glycoconjugates containing glucuronic acid and galactose as well as a reduction of

52 microfibrils had a higher content of (methyl)glucuronic acid and galactose in tension wood than in no

53 cose and rhamnose), and two hexuronic acids (glucuronic acid and galacturonic acid).

54 dation of not only alginate, but poly-beta-D-glucuronic acid and hyaluronic acid as well.

55 o its ability to sequester intracellular UDP-glucuronic acid and inhibition of hyaluronan synthase tr

56 tabolites; quercetin-3'-sulfate, quercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were

57 The exquisite complementarity between glucuronic acid and its binding site is highlighted by t

58 ows a variability along their sequence, as d-glucuronic acid and its C5 epimer, l-iduronic acid, can

59 ed that the resulting mutant lacked both UDP-glucuronic acid and its downstream product, UDP-xylose,

60 ible for the oxidation of UDP-glucose to UDP-glucuronic acid and its subsequent decarboxylation to UD

61 accommodation of alpha1,2-linked 4-methyl-D-glucuronic acid and L-arabinofuranose side chains.

62 ase responsible for the interconversion of d-glucuronic acid and l-iduronic acid residues encodes a t

63 ide composed of repeating disaccharides of D-glucuronic acid and N-acetyl-D-glucosamine (GlcNAc).

64 nctional chondroitin synthase K4CP catalyzes glucuronic acid and N-acetylgalactosamine transfer activ

65 block, and the two monosaccharide components glucuronic acid and N-acetylglucosamine and identify mar

66 ted HA synthase capable of transferring both glucuronic acid and N-acetylglucosamine groups.

67 long linear polymer composed of alternating glucuronic acid and N-acetylglucosamine residues, is an

68 inear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues, is an

69 onsisting of repeating disaccharide units of glucuronic acid and N-acetylglucosamine.

70 reaction of appropriately substituted azido-glucuronic acid and propargyluted N-acetyl glucosamine a

71 and two quercetin metabolites (quercetin-3-O-glucuronic acid and quercetin-3-O-sulfate) significantly

72 e propose a binding model for NAD(+) and UDP-glucuronic acid and the involvement of residues T(432),

73 catalyzes the conjugation of bilirubin with glucuronic acid and thus enhances bilirubin elimination;

74 eds in three chemical steps via UDP-4-keto-D-glucuronic acid and UDP-4-keto-pentose intermediates.

75 UXNAcS is specific and cannot utilize UDP-glucuronic acid and UDP-galacturonic acid as substrates.

76 olved in HA synthesis and uses cytosolic UDP-glucuronic acid and UDP-GlcNAc as substrates.

77 at synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as well as

78 ynthases (HAS1-3), which use cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as substrate

79 Chondroitin sulfate type C (CSC) contains glucuronic acid, and 90% of the GalNAc residues are sulf

80 Chondroitin sulfate type A (CSA) contains glucuronic acid, and 90% of the GalNAc residues are sulf

81 xylosyl residues is decorated by occasional glucuronic acid, and approximately one-half of the xylos

82 dic, alpha-fucosidic, alpha-mannosidic, beta-glucuronic acid, and beta-glucosamine linkages upon acti

83 ow that hemicellulose branches of arabinose, glucuronic acid, and especially glucuronate strengthen t

84 al other monosaccharides, including glucose, glucuronic acid, and N-acetylmannosamine, do not express

85 gy, we used purified S. equisimilis HAS, UDP-glucuronic acid, and UDP[beta-32P]-Glc-NAc to radiolabel

86 The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucos

87 component of the capsule (and, potentially, glucuronic acid, any-N-acetylated sugar, or ribitol).

88 s beta-glucuronidase enzymes that remove the glucuronic acid as a carbon source, effectively reversin

89 by the ORF atu2297, with UDP-glucose or UDP-glucuronic acid as sugar donors.

90 A Cer analogue with a D-glucuronic acid attached at the primary hydroxyl of N-pa

91 tic change of the reaction selectivity, with glucuronic acid being formed as the major product.

92 a variety of monodisperse hyaluronan (beta 4-glucuronic acid-beta 3-N-acetylglucosamine (HA)) oligosa

93 magnetic resonance studies confirmed that a glucuronic acid beta1,4-xylose disaccharide synthesized

94 duced repeating units of [-3-xylose-alpha1,3-glucuronic acid-beta1-].

95 uctions in the amount of [-3-xylose-alpha1,3-glucuronic acid-beta1-]n (hereafter referred to as LARGE

96 accharide repeating unit [-3-xylose-alpha1,3-glucuronic acid-beta1-]n by like-acetylglucosaminyltrans

97 ctive UDP-sugars to the non-reducing end of [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

98 with UDP and the acceptor substrate analog [glucuronic acid]beta1-3[galactose]beta1-O-naphthalenemet

99 resolution apo crystal structure of the UDP-glucuronic acid binding domain of human UGT isoform 2B7

100 ncoded protein is closely related to the UDP-glucuronic acid binding site consensus sequence, and the

101 A calcium-dependent glucuronic acid binding site shows distinctive structura

102 n to grow with N-acetylglucosamine but not d-glucuronic acid (both components of HA) as a sole carbon

103 The deletion of either sequence abolishes glucuronic acid but not N-acetylgalactosamine transfer a

104 ectins, is produced from the precursor UDP-D-glucuronic acid by the action of glucuronate 4-epimerase

105 Biosynthesis of UDP-glucuronic acid by UDP-glucose 6-dehydrogenase (UGDH) oc

106 M) enhanced the potency of UDPG (but not UDP-glucuronic acid) by 7-fold.

107 scovered that the published sequence for the glucuronic acid C5-epimerase responsible for the interco

108 t has an overall 37% homology to the human D-glucuronic acid C5-epimerase.

109 The synthesis of UDP-glucuronic acid can alter the NAD(+)/NADH ratio via the

110 residues predicted to interact with the UDP-glucuronic acid cofactor exhibited significantly impaire

111 Compound 5e was converted to beta-glucuronic acid conjugate 6e by the action of pig liver

112 or each analyte; a mixture of 1-pyOH and its glucuronic acid conjugate can be analyzed in 30 min.

113 nantly excreted (>87%) in human urine as the glucuronic acid conjugate, whereas the relative abundanc

114 Minor compounds were glucuronic acid conjugates of 9,10-dihydroxy-octadecanoi

115 iver, intestine and kidney, and catalyze the glucuronic acid conjugation of both endogenous compounds

116 recombinant human UGT isoforms, we show that glucuronic acid conjugation of the model substrate, (-)-

117 - O- tert-butyl diphenyl silyl group and a d-glucuronic acid-containing disaccharide thioglycoside wi

118 Only glucuronic acid-containing ligands produced complexes, a

119 e content of UDP-N-acetylhexosamines and UDP-glucuronic acid, correlating with the expression level o

120 Addition of the terminal residue (glucuronic acid) could not be detected; however, activit

121 (UDP-GlcA) is irreversibly catalyzed by UDP-glucuronic acid decarboxylase (UXS).

122 iosynthesis of UDP-xylose is mediated by UDP-glucuronic acid decarboxylase, which converts UDP-glucur

123 ransmembrane protein that functions as a UDP-glucuronic acid decarboxylase.

124 coccal sequence as putatively encoding a UDP-glucuronic acid decarboxylase.

125 Acetate or glucuronic acid decorations are exclusively found on eve

126 uronic acid degradation at pH 5, poly-beta-D-glucuronic acid degradation at pH 7, and alginate degrad

127 enosine diphosphate-activated platelets, UDP-glucuronic acid-dependent bilirubin conjugation was dete

128 ndogenous and exogenous chemicals by linking glucuronic acid donated by UDP-glucuronic acid to a lipo

129 o glycoside (25) with a trichloroacetimidate glucuronic acid donor (13), using a catalytic amount of

130 The Glc-GlcA disaccharide, featuring the glucuronic acid donor moiety, proved to be the most prod

131 We demonstrated that lpsL encoded a UDP-glucuronic acid epimerase activity that was reduced in t

132 igh-resolution crystal structures of the UDP-glucuronic acid epimerase from Bacillus cereus The geome

133 a gene previously predicted to encode a UDP-glucuronic acid epimerase.

134 espect to chain length, sulfate content, and glucuronic acid epimerization content, resulting in a di

135 Although glucuronic acid esters are often considered to be of ver

136 eactions revealed that the reactivity of the glucuronic acid esters studied is sufficient to provide

137 The relative reactivity of glucuronic acid esters was established in a series of co

138 4" oxidation and C-6" decarboxylation of UDP-glucuronic acid, followed by the C-4" transamination of

139 and C-6" decarboxylation of [alpha-(32)P]UDP-glucuronic acid, followed by transamination to generate

140 ,2-linked glucuronic acid and 4-O-methylated glucuronic acid from the plant cell wall polysaccharide

141 ol g(-1)), whereas binding of the competitor glucuronic acid (GA) and other monosaccharides was consi

142 xtracts of the mutants completely lacked UDP-glucuronic acid:Galbeta1,3Gal-R glucuronosyltransferase

143 suitable protected thioaldoses derived from glucuronic acid (GlcA) and galactose (Gal).

144 formation occurs by the copolymerization of glucuronic acid (GlcA) and N-acetylglucosamine (GlcNAc)

145 lcNAc) or N-sulfated glucosamine (GlcNS) and glucuronic acid (GlcA) as the primary sites and the link

146 uishing the epimers iduronic acid (IdoA) and glucuronic acid (GlcA) has been a long-standing challeng

147 corporation of radioactive glucose (Glc) and glucuronic acid (GlcA) into lipid-linked disaccharides i

148 ore-shell particles specifically recognizing glucuronic acid (GlcA) or N-acetylneuraminic acid (NANA)

149 glycan decorations that include a conserved glucuronic acid (GlcA) residue and various additional su

150 ries a pentose linked 1-2 to the alpha-1,2-d-glucuronic acid (GlcA) side chains on the beta-1,4-Xyl b

151 ta-glucuronidase (GUS) enzymes that liberate glucuronic acid (GlcA) sugars from small-molecule conjug

152 the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within HS.

153 MIPs were prepared with the templates D-glucuronic acid (GlcA), a substructure of hyaluronan, an

154 The distribution of 13C in the Man, Xyl, glucuronic acid (GlcA), and O-acetyl constituents of nat

155 merase (Hsepi) catalyzes C5-epimerization of glucuronic acid (GlcA), converting it to iduronic acid (

156 yzes C5-epimerization of the HS component, d-glucuronic acid (GlcA), into l-iduronic acid (IdoA), whi

157 residues substituted with alpha(1,2)-linked glucuronic acid (GlcA).

158 Glucuronic acid (GlcAp) and/or methylglucuronic acid (Me

159 6OSO3), but contained a higher proportion of glucuronic acid GlcUA-GlcNSO3(6OSO3) and IdUA-GlcNSO3(6O

160 is a membrane-bound enzyme that utilizes UDP-glucuronic acid (GlcUA) and UDP-GlcNAc to synthesize HA.

161 at transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA) in alternative positions in the

162 sed of alternating beta-1,3-Glc and beta-1,4-glucuronic acid (GlcUA) linkages.

163 atalyzes sugar transfer from UDP-Glc and UDP-glucuronic acid (GlcUA) to a polymer with the repeating

164 yltransferase that catalyzes the transfer of glucuronic acid (GlcUA) to the common growing linker reg

165 s comprising 3-sulfated rhamnose linked to d-glucuronic acid (GlcUA), l-iduronic acid (IdoUA), or d-x

166 PmHAS possesses both GlcNAc-transferase and glucuronic acid (GlcUA)-transferase activities.

167 nd without depletion of the HA precursor UDP-glucuronic acid (GlcUA).

168 Reaction of beta-glucuronic acid glycoside of 4-hydroxy-3-nitrobenzyl alc

169 al preparations resulted in no metabolite or glucuronic acid-HPPH conjugate production.

170 ogether with the aglycon and alpha- and beta-glucuronic acid hydrolysis products.

171 may be close to the 3-hydroxyl group of beta-glucuronic acid in a HNK-1 acceptor.

172 esonance that revealed a crucial role of the glucuronic acid in antibody binding.

173 w that the carboxyl group on nonreducing end glucuronic acid in dodecasaccharide motif is important f

174 o distinguish the epimers iduronic acid from glucuronic acid in heparan sulfate tetrasaccharides and

175 a1-4 linkage between N-acetylglucosamine and glucuronic acid in hyaluronan polymers via a substrate-a

176 he content of the polysaccharide component D-glucuronic acid in the biofilm.

177 s undergo detoxification by conjugation with glucuronic acid in the liver via the action of UDP-glucu

178 Nrf2 promoted conjugation of ABP with glucuronic acid in the liver, increasing urinary excreti

179 n, ideal for decarboxylation of UDP-4-keto-D-glucuronic acid in the second chemical step.

180 E, quercetin-3-O-glucoside and quercetin-3-O-glucuronic acid inhibited significantly (p<0.05) ACE act

181 c acid and decarboxylation of the UDP-4-keto-glucuronic acid intermediate.

182 The oxidative decarboxylation of UDP-glucuronic acid is catalyzed by the 345-residue C-termin

183 In this process, glucuronic acid is conjugated to a drug or a drug metabo

184 UDP-glucuronic acid is converted to UDP-galacturonic acid en

185 d-Glucuronic acid is further metabolized to xylitol via th

186 ctivity of B3GAT1, we were able to show that glucuronic acid is present on antennae of plasma glycopr

187 pletion of the hyaluronic acid precursor UDP-glucuronic acid is sufficient to inhibit several mesench

188 In humans, conjugation with glucuronic acid is the most important phase II metabolic

189 In mammalian organisms, UDP-glucuronic acid is typically used in the transfer reacti

190 at is specific for the l-rhamnose-alpha1,4-d-glucuronic acid linkage that caps the side chains of com

191 Glucuronic acid linked prodrugs of O(6)-benzylguanine an

192 ated Az29, possesses two PEtn moieties and a glucuronic acid linked to a Gal-extended Nz28.

193 ranched surface structure containing glucose-glucuronic acid linked to a glucose-rhamnose-rhamnose-rh

194 vered that heparanase cleaves the linkage of glucuronic acid linked to glucosamine carrying 6-O-sulfo

195 n those measured on a mixture of pyruvic and glucuronic acids (logK = 2.2), which are the two constit

196 Glucuronic acid modification was observed in E. coli B,

197 leavage of ester linkages between lignin and glucuronic acid moieties on glucuronoxylan in plant biom

198 e of ester linkages found between lignin and glucuronic acid moieties on glucuronoxylan in plant biom

199 f sugar residues and epimerizations of their glucuronic acid moieties.

200 etraazacyclododecane) bearing a pendant beta-glucuronic acid moiety connected by a self-immolative li

201 GlcAT-I transfers a glucuronic acid moiety from the uridine diphosphate-gluc

202 cid hydrolysis, resulting in a Xyl:arabinose:glucuronic acid molar ratio of approximately 105:34:1.

203 fucose, d-mannose, d-galactose, d-glucose, d-glucuronic acid, N-acetyl-d-galactosamine, and N-acetyl-

204 -ribofuranose and 3-O-[(R)-1-carboxyethyl]-D-glucuronic acid (nosturonic acid) pendant groups.

205 ccus neoformans comprises manose, xylose and glucuronic acid, of which mannose is the major constitue

206 scribed, which arises due to the addition of glucuronic acid on the third heptose with a concomitant

207 transferase GUX1, and so the even pattern of glucuronic acid on the xylan is lost.

208 residues in the capsule are derived from UDP-glucuronic acid or its metabolites.

209 di- or trisaccharide and at position 6 with glucuronic acid or rhamnosyl glucuronic acid.

210 highly sulfated polysaccharide consisting of glucuronic acid (or iduronic acid) linked to glucosamine

211 of acidic sugars N-acetylneuraminic acid and glucuronic acid out of lysosomes.

212 e-uronic acid intermediate that results from glucuronic acid oxidation, placing the C4' atom in posit

213 ctivity against hyaluronan (HA), poly-beta-d-glucuronic acid (poly-GlcUA), and poly-beta-d-mannuronic

214 lation of the bacterial N-acetylglucosaminyl-glucuronic acid polymer K5 under conditions where the ho

215 effects in rodents, and are conjugated with glucuronic acid prior to excretion in human urine.

216 We propose that the regulation of UDP-glucuronic acid production in a specific subset of vulva

217 indicating that an alternate pathway for UDP-glucuronic acid production was not used.

218 d from partial desulfation demonstrated that glucuronic acid rather than iduronic acid residues are i

219 lysaccharide composed of N-acetylglucosamine-glucuronic acid repeats, is found in the extracellular m

220 acid and appears to require two 4-O-methyl-D-glucuronic acid residues for substrate recognition and/o

221 on, BtGH115A, hydrolyzes terminal 4-O-methyl-glucuronic acid residues from decorated arabinogalactan

222 dase was used to remove nonreducing-terminal glucuronic acid residues from oligosaccharides.

223 ily 2 glycosylhydrolases that cleaves beta-D-glucuronic acid residues from the nonreducing termini of

224 ly incorporated xylose (Xyl), arabinose, and glucuronic acid residues from their corresponding uridin

225 Odd-numbered oligosaccharides with terminal glucuronic acid residues isolated from hyaluronidase dig

226 ults in a specific defect in the addition of glucuronic acid residues onto xylans.

227 iency, both contain a trisaccharide with two glucuronic acid residues that enabled the identification

228 ride of alternating N-acetyl-glucosamine and glucuronic acid residues, is ubiquitously expressed in v

229 ride units of N-acetyl-D-galactosamine and d-glucuronic acid residues, modified with sulfated residue

230 idues but lacks any 2-O-sulfated iduronic or glucuronic acid residues.

231 rface than thought previously, such that a D-glucuronic acid ring makes stacking and ionic interactio

232 ynthesis mutants, such as the replacement of glucuronic acid side chains with methylglucuronic acid s

233 s (MS) I and II through their coupling at C3 glucuronic acid site with dodecylamine.

234 (GXMT) that catalyzes 4-O-methylation of the glucuronic acid substituents of this polysaccharide.

235 xylan, generating products with a 4-O-methyl-glucuronic acid-substituted xylose residue one position

236 GUX1 (glucuronic acid substitution of xylan 1) and GUX2, recen

237 noglycan composed of N-acetylglucosamine and glucuronic acid subunits.

238 ernating beta1,3-N-acetylglucosamine-beta1,4-glucuronic acid sugar chain by the sequential addition o

239 nd xenobiotic compounds by linking them to a glucuronic acid sugar for GI excretion.

240 UGTs catalyze the covalent addition of glucuronic acid sugar moieties to a host of therapeutics

241 ects observed for amino acids closest to the glucuronic acid sugar transferred to the acceptor molecu

242 ansport rate for N-acetylneuraminic acid and glucuronic acid, suggesting that it may be directly invo

243 (Ssp) show homology to genes involved in UDP-glucuronic acid synthesis.

244 specificity and allows phosphorylation of d-glucuronic acid, the 4-epimer of GalA.

245 charides containing terminal 4,5-unsaturated glucuronic acid, the nonreducing end disaccharide moiety

246 found in natural polysaccharides containing glucuronic acid, the oxidation of the primary alcohol at

247 nts may be linked to the availability of UDP-glucuronic acid; therefore UGDH is an intriguing therape

248 ls by linking glucuronic acid donated by UDP-glucuronic acid to a lipophilic acceptor substrate.

249 "reversible" catalytic mode by converting a glucuronic acid to an iduronic acid residue, and vice ve

250 lso serve as a one-way catalyst to convert a glucuronic acid to an iduronic acid residue, displaying

251 coded by PsUGT1 catalyzes conjugation of UDP-glucuronic acid to an unknown compound.

252 Chst10 adds sulfate to glucuronic acid to form a carbohydrate antigen, HNK-1, i

253 precedented oxidative decarboxylation of UDP-glucuronic acid to form uridine 5'-(beta-l-threo-pentapy

254 )-dependent oxidative decarboxylation of UDP-glucuronic acid to generate a UDP-4'-keto-pentose sugar

255 ehydrogenase, which is capable of converting glucuronic acid to glucaric acid.

256 ylgalactosamine may precede epimerization of glucuronic acid to iduronic acid during dermatan sulfate

257 san with C(5)-epimerase converts some of the glucuronic acid to iduronic acid, thus becoming a substr

258 The HS C(5)-epimerase converts glucuronic acid to iduronic acid.

259 fication reactions is the epimerization of D-glucuronic acid to its C5-epimer L-iduronic acid, which

260 UGT1As add glucuronic acid to many drugs, modifying their activity

261 UGT1As add glucuronic acid to many drugs.

262 3)-glucuronyltransferases, one of which adds glucuronic acid to protein-linked galactose-beta(1, 4)-N

263 the NAD(+)-dependent decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and (ii) the N-1

264 One activity is to decarboxylate UDP-glucuronic acid to UDP-beta-l-threo-pentopyranosyl-4''-u

265 hase (AXS) catalyzes the conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose.

266 shown to encode an enzyme that converts UDP-glucuronic acid to UDP-xylose for capsule biosynthesis,

267 neoformans gene catalyzed conversion of UDP-glucuronic acid to UDP-xylose, as confirmed by NMR analy

268 ase (UXS) catalyzes decarboxylation of UDP-D-glucuronic acid to UDP-xylose.

269 ronic acid decarboxylase, which converts UDP-glucuronic acid to UDP-xylose.

270 +-dependent oxidative decarboxylation of UDP-glucuronic acid to yield the UDP-4''-ketopentose, uridin

271 olase-like catalytic mechanism to facilitate glucuronic acid transfer.

272 d II enzymes (cytochrome P450 (CYP), uridine glucuronic acid transferase (UGT), and sulfotransferase

273 into two single-action glycosyltransferases (glucuronic acid transferase and N-acetylglucosamine tran

274 ) to the key metabolic precursor UDP-alpha-d-glucuronic acid (UDP-GlcA) and display specificity for U

275 e authentic sugar nucleotide precursors, UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylglucosamine (

276 together with UDP-xylose is formed from UDP-glucuronic acid (UDP-GlcA) by UDP-Api synthase (UAS).

277 The biosynthesis of UDP-Xyl from UDP-glucuronic acid (UDP-GlcA) is irreversibly catalyzed by

278 UDP-glucuronic acid (UDP-GlcA) is the precursor of many plan

279 ing (1) the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcA) to the UDP-4' '-ketopentose [

280 ) catalyzes the epimerization of UDP-alpha-D-glucuronic acid (UDP-GlcA) to UDP-alpha-D-galacturonic a

281 is synthesized by the decarboxylation of UDP-glucuronic acid (UDP-GlcA).

282 nverts UDP-2-acetamido-3-amino-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NA) to UDP-2,3-diacetamido-2

283 NAc3NA) to UDP-2,3-diacetamido-2,3-dideoxy-d-glucuronic acid (UDP-GlcNAc3NAcA).

284 ed nucleotide sugars UDP-2-acetamido-2-deoxy-glucuronic acid (UDP-GlcNAcA) and UDP-2-acetamido-2-deox

285 te (Glc-6-P) --> Glc-1-P --> UDP-Glc --> UDP-glucuronic acid (UDP-GlcUA) --> (GlcUA-Glc)(n).

286 accharide units from the donor molecules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine

287 oniae requires UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3)-be

288 resence of protein-mediated transport of UDP-glucuronic acid (UDP-GlcUA) in rat liver endoplasmic ret

289 lcUA-(1-] from UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) is catalysed by the type 3 s

290 Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as

291 nic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region

292 trate for all glucuronidation reactions, UDP-glucuronic acid (UDP-GlcUA), was determined using a rapi

293 cerevisiae expressing SQV-7 transported UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-gala

294 ctionalized side chain incorporated into the glucuronic acid unit that is attached to a triterpenoid

295 The abundance of the 4-O-methyl-alpha-d-glucuronic acid was not previously reported.

296 use steroid hormones are often conjugated to glucuronic acid, we hypothesized that Chst10 sulfates gl

297 ercetin-3-glucuronic acid and isorhamnetin-3-glucuronic acid were effective at physiological concentr

298 talyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis

299 Glucuronic acid, which is transferred to the AGP glycan

300 mposed of disaccharide units of GlcNAc and d-glucuronic acid with alternating beta-1,4 and beta-1,3 g