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1      After oral administration, ezetimibe is glucuronidated.
2 or-alpha-muricholic acid); the remainder was glucuronidated.
3     Additionally UGT1A10-expressing cultures glucuronidated 17beta-[(14)C]estradiol, whereas cultures
4                   The human liver microsomes glucuronidated 4-OH-RA and 4-OH-RAc with 6- and 3-fold h
5 nduction of UGT1A7 may explain the increased glucuronidating activities toward benzo(a)pyrene-7,8-dio
6 le in this interindividual variability, NNAL-glucuronidating activities were analyzed in 78 human liv
7                                No detectable glucuronidating activity against BPD was observed by UGT
8 r L175Q, expressed in COS-1 cells, bilirubin glucuronidating activity at both pH 6.4 and 7.6 demonstr
9                     Benzo(a)pyrene-7, 8-diol glucuronidating activity was detected (0.4 nmol/10(6) ce
10               Little or no difference in TAM glucuronidating activity was observed for the UGT1A8(173
11     Gunn rats and CN-I patients lacked SN-38 glucuronidating activity, indicating the role of UGT1 is
12 in, a breakdown product of heme, is normally glucuronidated and excreted by the liver into bile.
13 as reduced 30% with 12-D(3)NVP vs NVP, while glucuronidated and glutathione-conjugated metabolites in
14 no- and dihydroxy-metabolites, together with glucuronidated and sulfated metabolites, were detected.
15 ve directly measured free, conjugated (e.g., glucuronidated), and substituted (e.g., chlorinated) for
16 fluorescein was well transported, was partly glucuronidated, and had normal choleretic activity.
17 ody fluids mainly in the form of methylated, glucuronidated, and sulfated derivatives (in total, 21 d
18 ospho glucuronosyltransferase 2B17 (UGT2B17) glucuronidates androgens and xenobiotics including certa
19 determined that human recombinant UGT2B7 can glucuronidate atRA, 4-OH-RA, and 4-OH-RAc with activitie
20 xpressed by a baculovirus system selectively glucuronidated bile acids, particularly hyodeoxycholic a
21  a Tyr/Leu at position 170/171; this isoform glucuronidated bilirubin at 1/10 the level of that by UG
22             Its active metabolite, SN-38, is glucuronidated by hepatic uridine diphosphate glucuronos
23            NSAIDs, particularly aspirin, are glucuronidated by UGT1A6 and some classes of NSAIDs are
24 oisomers of one of its main metabolites, the glucuronidated carboxylate derivative, can be resolved b
25 nary nicotine metabolites are in the form of glucuronidated compounds.
26 rinary metabolites in the form of phase II N-glucuronidated compounds.
27 cts that consumed JWH-018 primarily excreted glucuronidated conjugates of 5-(3-(1-naphthoyl)-1H-indol
28 tion of buprenorphine, norbuprenorphine, and glucuronidated conjugates was developed and validated.
29 grated peak area for putative sulfonated and glucuronidated E2 metabolites showed a similar trend.
30 missense polymorphisms in the two major NNAL-glucuronidating enzymes UGT1A4 and UGT2B7.
31 d an HPLC peak corresponding to sulfated and glucuronidated estradiol in serum from wild-type but not
32 rometry revealed that Chst10 indeed sulfates glucuronidated estrogen, testosterone, and other steroid
33                    The ability of UGT1A10 to glucuronidate estrone represents only the second example
34                                  NorCDCA was glucuronidated extensively (70%, rat; 40%, hamster).
35                The rank order of affinity of glucuronidated ezetimibe for NPC1L1 in each species corr
36 stine and then in the liver to sulphated and glucuronidated forms that are exported to target organs.
37  two hydroxylated intermediates as well as a glucuronidated hydroxyl-metabolite of gemfibrozil.
38 ed by the normal proliferating marrow and is glucuronidated in the liver.
39 sive study of critical properties concerning glucuronidating isozymes in alimentary tissues.
40 ted into the liver where only 41% of BPS was glucuronidated, leading to a systemic bioavailability of
41                               NVP-AUY922 was glucuronidated less than previously described isoxazoles
42 lected, and the concentrations of FL and its glucuronidated metabolite (FL-Glu) were measured by HPLC
43 ated intracellular testosterone primarily as glucuronidated metabolites.
44                                 The level of glucuronidated nicotine or cotinine in 112 HLM samples w
45 UGTs from the 1A family for their ability to glucuronidate p-nitrophenol (pNP) and 4-methylumbellifer
46 d, sulfated/hydroxylated, sulfated PCMC, and glucuronidated PCMC) were identified using the in vitro
47                                      Several glucuronidated polyphenol metabolites did not exhibit si
48 yl)-1-butanol (NNAL), which, in turn, can be glucuronidated, producing [4-methylnitrosamino)-1-(3-pyr
49         In conclusion, in humans, norUDCA is glucuronidated rather than amidated.
50 c acid, we hypothesized that Chst10 sulfates glucuronidated steroid hormone to regulate steroid hormo
51 in the synthesis, since attempts to directly glucuronidate the aglycon, aglycon derivatives, and othe
52 ked interpatient variations and proficiently glucuronidated the two anticancer drugs.
53  cellulose synthase-like enzyme can not only glucuronidate triterpenoid aglycones but also alter the
54 the members of clade two are also capable of glucuronidating two consecutive xyloses.
55 cubated with human liver slices, norUDCA was glucuronidated, whereas UDCA was conjugated with glycine