ライフサイエンスコーパス: glutamic acid

1 eptidase in which the third zinc ligand is a glutamic acid).

2 me-modified lysine, C' = citrulline, and E = glutamic acid).

3 ne, aspartic acid, asparagine, tyrosine, and glutamic acid).

4 from glucose, guanine, and p-aminobenzoyl-l-glutamic acid.

5 s associated with consumption of excess free glutamic acid.

6 caspases can also hydrolyze substrates after glutamic acid.

7 ycine, l-proline, l-serine, l-alanine, and l-glutamic acid.

8 r in the literature for a racemic mixture of glutamic acid.

9 of tRNAs specific for lysine, glutamine and glutamic acid.

10 tion of HMF from fructose in the presence of glutamic acid.

11 e digestion motifs flanked with aspartic and glutamic acid.

12 molecule was replaced by the side chain of a glutamic acid.

13 or charged residues tyrosine, histidine, and glutamic acid.

14 ially available methyl (R)-(+)-lactate and l-glutamic acid.

15 ive mutagenesis analysis, we identified that glutamic acid 14 (E14) of vBcl-2 is critical for KSHV ly

16 to a chemical reaction, the deprotonation of glutamic acid 148 (E148).

17 he lumen-exposed residues, threonine 162 and glutamic acid 173, form stabilizing hydrogen bonds betwe

18 nd kinetics of (S)-4-(3-[18F]fluoropropyl)-l-glutamic acid ((18)F FSPG) in healthy volunteers and to

19 radiotracer, (S)-4-(3-[(18)F]fluoropropyl)-L-glutamic acid ([(18)F]FSPG), decreases in proportion to

20 with 3-aminophenyl boronic acid (APB) and L-glutamic acid-(2,2,2)-trichloroethyl ester (GTE).

21 used significantly higher levels (p<0.05) of glutamic acids (343.0+/-22.09mg/100g), total FAAs (1720.

22 he DOTAGA (1,4,7,10-tetraazacyclododecane-1-(glutamic acid)-4,7,10-triacetic acid) conjugate PSMA I&T

23 nT, tyrosine-43, lysine-69, arginine-254 and glutamic acid-493, were required for activity.

24 acids, L-aspartic acid 4-methyl ester and L-glutamic acid 5-methyl ester, is a convenient and sensit

25 External glutamic acid 623 (E623) is key for TMEM16A's ability to

26 ngs we propose that external protons titrate glutamic acid 623, which enables voltage activation of T

27 Regarding total amino acids, aspartic and glutamic acids (9-10 mg/g) were the major compounds.

28 erred a small-plaque avirulent phenotype and glutamic acid a large-plaque virulent phenotype.

29 lyceraldehyde 3-phosphate dehydrogenase with glutamic acid, a malonyllysine mimic, suppressed its enz

30 feri and Burkholderia thailandensis bound to glutamic acid, a TrpRS from the eukaryotic pathogen Ence

31 nificant effects were noticed in the case of glutamic acid, alanine, aspartic acid and proline betwee

32 es involved in glutamine catabolism, such as glutamic acid, alanine, glycine, pyrimidine, and creatin

33 We show that protonation of the conserved glutamic acid alters the peptide insertion depth in the

34 Glutamic acid and alanine make up more than 60 per cent

35 f glutamic acid (p < 0.05) and 200 mug/mL of glutamic acid and aspartic acid (p < 0.001) without affe

36 d lower plasma concentrations of citrulline, glutamic acid and carnitine at 24 hrs after enrolment an

37 e biosynthetic pathway to kainic acid from l-glutamic acid and dimethylallyl pyrophosphate in red mac

38 Free glutamic acid and free aspartic acid found in the PPI hy

39 m, were conjugated quickly and directly with glutamic acid and glutamine, and further with peptides,

40 PELP1 (proline, glutamic acid and leucine rich protein 1) is a nuclear r

41 containing multi-layers of short alternating glutamic acid and lysine (EK) peptides as a facile, high

42 TPs calculated from delta (15)N values of glutamic acid and phenylalanine, which range from 8.3-33

43 s from wet solids were significantly rich in glutamic acid and proline.

44 ng 98% of ascorbic acid and 100% of glycine, glutamic acid and uric acid.

45 ghest regression coefficients were found for glutamic acid and valine, with regards to blood orange j

46 l interference from ascorbic acid, cysteine, glutamic acid, and glucose was also studied, and the obt

47 Here, we identify proline, glutamic acid, and leucine-rich protein 1 (PELP1), a chr

48 f DMD cardiomyopathy in which phosphomimetic glutamic acids are substituted for serines at these resi

49 served when acidic amino acids, aspartic and glutamic acids, are present near the cleavage site.

50 d with nontumor tissues (proline, threonine, glutamic acid, arginine, N1-acetylspermidine, xanthine,

51 as compared to adsorption of soy protein and glutamic acid as common ingredients.

52 complex with the Nix LIR peptide containing glutamic acids as phosphomimetic residues and NMR experi

53 here is no interference from d-glucose and l-glutamic acid, ascorbic acid and o-nitrophenol.

54 ant amino acids that contributed to flavour (glutamic acid, aspartic acid and alanine) were present a

55 tin-1, QHREDGS (glutamine-histidine-arginine-glutamic acid-aspartic acid-glycine-serine), as a therap

56 either the wild type (WT) or with alanine or glutamic acid/aspartic acid substitutions at the phospho

57 the CBP/p300-interacting transactivator with glutamic acid/aspartic acid-rich carboxyl-terminal domai

58 chemically well-defined amphoteric carriers, glutamic acid, aspartyl-histidine (Asp-His), cycloserine

59 e of F-III was due to the presence of free l-glutamic acid at 6 times, while FII and FIV were due to

60 For rat Glut5, a change of glutamine to glutamic acid at codon 166 (p.Q166E) has been reported t

61 n of the AIF-MIF interaction, or mutation of glutamic acid at position 22 in the catalytic nuclease d

62 with previous studies, we demonstrate that a glutamic acid at position 296 results in attenuation.

63 thin the C terminus of LukA, we identified a glutamic acid at position 323 that is critical for LukAB

64 In this study we found that KIR2DL2/L3 with glutamic acid at position 35 (E(35)) are functionally st

65 rily linked to HLA-DPB1 alleles possessing a glutamic acid at position 69 of the beta-chain.

66 ions not previously identified, specifically glutamic acid at positions 10 or 11 or lysine at positio

67 71 mutant, containing lysine, glutamine, and glutamic acid at the respective residues 98, 145, and 16

68 molecular baskets 1(6-), each with three (S)-glutamic acids at its rim, were found (NMR, ITC) to comp

69 k copolymers, poly(ethylene glycol)-b-poly(L-glutamic acid)-b-poly(L-phenylalanine), which effectivel

70 We conjugate doxorubicin to poly(L-glutamic acid) by means of a pH-sensitive cleavable link

71 tudy, we examined the efficacy of poly-gamma-glutamic acid/chitosan (PC) nanogel as an adjuvant for t

72 , aspartic acid (coded by GAY [Y = U or C]), glutamic acid (coded by GAZ [Z = A or G]), glycine (code

73 tonia is caused by an in-frame deletion of a glutamic acid codon in the gene encoding the AAA+ ATPase

74 D-aas such as D-Asp (aspartic acid), D-Glu (glutamic acid), combined D-[Asp/Glu] and others were eac

75 ter enrolment and significantly lower plasma glutamic acid concentrations (74.4 versus 98.2 mumol/L)

76 nd non-coding regions explained aspartic and glutamic acid consumption differences, likely due to a p

77 el B(12)-targeted poly(ethylene glycol)-poly(glutamic acid) copolymers as excipients suitable to be f

78 2)-targeted poly(ethylene glycol)-block-poly(glutamic acid) copolymers.

79 tic amino acid aspartic acid could fully and glutamic acid could partially reconstitute the level of

80 predicted absolute growth rates of the alpha-glutamic acid crystal at lower supersaturations are in r

81 -DOTA-E[c(RGDfK)](2), where E[c(RGDfk)](2) = glutamic acid-[cyclo(arginyl-glycyl-aspartic acid-D-phen

82 CBP/p300-interacting transactivators with E [glutamic acid]/D [aspartic acid]-rich-carboxylterminal d

83 ved DC were pulsed with preproinsulin (PPI), glutamic acid decarboxylase (65-kDa isoform; GAD65), and

84 gamma aminobutyric acid synthesizing enzyme glutamic acid decarboxylase (GAD) and choline acetyltran

85 High levels of antibodies against glutamic acid decarboxylase (GAD) are observed in patien

86 is is controlled by enzymes derived from two glutamic acid decarboxylase (GAD) genes, GAD1 and GAD2,

87 Antibodies to glutamic acid decarboxylase (GAD) have been associated w

88 of activation (Fos) of GABAergic neurons and glutamic acid decarboxylase (GAD) mRNA expression in the

89 pocampal slices and activity measurements of glutamic acid decarboxylase (GAD), a PLP-dependent enzym

90 dinucleotide phosphate-diaphorase (NADPH-d), glutamic acid decarboxylase (GAD), cytochrome oxidase (C

91 e and some were parvalbumin-, calbindin-, or glutamic acid decarboxylase (GAD)-67-positive.

92 hibitory neurotransmitter, is synthesized by glutamic acid decarboxylase (GAD).

93 nobutyric acid (GABA) transporter (vGAT) and glutamic acid decarboxylase (GAD)65 in the GABAergic con

94 Additionally, glutamic acid decarboxylase (GAD)65-loaded tolDCs from w

95 Here, we study the distribution of glutamic acid decarboxylase (GAD)67 and GLY transporter

96 tibodies against insulin, the 65-kDa form of glutamic acid decarboxylase (GAD65), insulinoma-associat

97 were triple-labeled for the 65 kD isoform of glutamic acid decarboxylase (GAD65), PV and the GABA(A)

98 Gad1 gene-encoded 67-kDa protein isoform of glutamic acid decarboxylase (GAD67) is a hallmark of sch

99 ntain normal levels of the 67 kDa isoform of glutamic acid decarboxylase (GAD67) protein, the enzyme

100 to lower expression of the 67-kDa isoform of glutamic acid decarboxylase (GAD67), a key enzyme for GA

101 in cells that contain the 67 kDa isoform of glutamic acid decarboxylase (GAD67-GFP), or Cre-recombin

102 P), or Cre-recombinase in cells that contain glutamic acid decarboxylase (GAD; GAD2-cre).

103 ext, we produced conditional null alleles of Glutamic acid decarboxylase 1 (Gad1) and Resistant to di

104 nerated transgenic mouse lines that suppress glutamic acid decarboxylase 1 (GAD1) in either cholecyst

105 Levels of gamma-aminobutyric acid (GABA) and glutamic acid decarboxylase 1 (GAD1), the enzyme that sy

106 hypothalamus activated a small population of glutamic acid decarboxylase 2 (GAD2)-expressing neurons

107 The glutamic acid decarboxylase 2 but not the parvalbumin su

108 In contrast, the silencing of glutamic acid decarboxylase 2-positive interneurons, whi

109 n of T1D-related autoantigens [proinsulin or glutamic acid decarboxylase 65 (GAD)] delayed T1D onset,

110 tis Abs as well as thyroperoxidase (TPO) and glutamic acid decarboxylase 65 (GAD65) Abs.

111 Glutamic acid decarboxylase 65 (GAD65) and autoantibodie

112 been identified, including orexin cells and glutamic acid decarboxylase 65 (GAD65) cells, but their

113 gic knowledge on cerebellar ataxia (CA) with glutamic acid decarboxylase 65 antibodies (GAD65-Abs) is

114 globulin) and diabetes-related autoantigens (glutamic acid decarboxylase 65, insulin, heat shock prot

115 brane protein (PMP) antibody positivity; and glutamic acid decarboxylase 65-kDa isoform (GAD65) antib

116 atus of the second GABA-synthesizing enzyme, glutamic acid decarboxylase 65-kDa isoform (GAD65), rema

117 pendent expression levels of parvalbumin and glutamic acid decarboxylase 67 (GAD67) in schizophrenia

118 dies have consistently found lower levels of glutamic acid decarboxylase 67 (GAD67) messenger RNA (mR

119 of DNMT1 to psychiatric candidate promoters (glutamic acid decarboxylase 67, Reelin, and brain-derive

120 Levels of the GABA-synthesizing enzyme glutamic acid decarboxylase 67-kDa isoform (GAD67) in th

121 Four patients also had high glutamic acid decarboxylase antibodies (>1000 U/ml), and

122 ms of pathology, many patients with SPS have glutamic acid decarboxylase antibodies (GAD-ab), but the

123 Little is known of glutamic acid decarboxylase antibodies (GAD-abs) in the

124 riodontal conditions, retinopathy, and serum glutamic acid decarboxylase antibody (GADA) titers in re

125 Two anti-glutamic acid decarboxylase antibody-positive patients w

126 balanced for age, sex, disease duration, and glutamic acid decarboxylase autoantibody titers.

127 ain development through direct activation of glutamic acid decarboxylase enzyme isoforms that convert

128 he presence of the GABA-synthesizing enzyme, glutamic acid decarboxylase in EC were confirmed by immu

129 brillary acidic protein-immunocytochemistry, glutamic acid decarboxylase in situ hybridization, and p

130 hat specific promoter regulatory elements of glutamic acid decarboxylase isoforms (Gad1 and Gad2), wh

131 IgE responses to insulin, autoantibodies to glutamic acid decarboxylase or insulinoma-associated ant

132 We also used immunohistochemistry for glutamic acid decarboxylase to distinguish GABAergic fro

133 gic neurons expressing different isoforms of glutamic acid decarboxylase were found to have different

134 re also immunopositive to antibodies against glutamic acid decarboxylase, suggesting that they use ga

135 ith SPS have antibodies directed against the glutamic acid decarboxylase, the rate-limiting enzyme fo

136 lear layer and in the ganglion cell layer is glutamic acid decarboxylase-positive and shows the morph

137 ve for GABA and the GABA-synthesizing enzyme glutamic acid decarboxylase.

138 e transporter 2; VGluT2) and GABA signaling (glutamic acid decarboxylase; GAD, and vesicular GABA tra

139 sporter 1 (VGLUT1) and the 65 kDa isoform of glutamic acid-decarboxylase (GAD65) as markers of, respe

140 o patients with novel de novo Tpm3.12 single glutamic acid deletions at positions DeltaE218 and Delta

141 d quantification of the adsorbed amino acid (glutamic acid) demonstrated that 1 mg of homochiral poly

142 A beta-glutamic acid dendron anchor was used to attach a PEG ch

143 With a protected glutamic acid derivate as the starting material, the pro

144 toes resulted in robust GABA production from glutamic acid derived from blood protein digestion.

145 d-Alanine and d-glutamic acid derived from peptidoglycan decomposition e

146 d allylation of serine-, aspartic acid-, and glutamic acid-derived organozinc reagents, followed by c

147 His6-OPH) and poly(ethylene glycol)-b-poly(l-glutamic acid) diblock copolymer.

148 10(4) M(-1)), whereas sucrose, aspartame and glutamic acid did not bind at all.

149 reported that the HPV-31 E2 Y138 mutation to glutamic acid did not bind to the Brd4 C-terminal motif

150 Arginine-glutamic acid dipeptide repeats (RERE) is located in the

151 at binding did not require the gamma-carboxy glutamic acid domain.

152 w potatoes and also thermally generated from glutamic acid during frying.

153 ase structural fold for the N-prenylation of glutamic acid during the biosynthesis of the potent neur

154 K66 in the SMG7 14-3-3-like domain with the glutamic acid (E) abolishes interactions with its client

155 y via a Ca(2+) binding pocket with conserved glutamic acid (E) and aspartic acid (D) residues.

156 We found that another rare substitution, glutamic acid (E) at position 206, significantly reduced

157 acid residues, glycine (G), serine (S), and glutamic acid (E) at positions 172, 207, and 212, respec

158 However, mutation that substituted glutamic acid (E) for glutamine (Q) at amino acid positi

159 The tyrosine-to-glutamic acid (E) mutant Y131E, which may mimic phosphot

160 The tyrosine to glutamic acid (E) mutant Y138E, which can mimic phosphot

161 C-terminal domain of connexin43 (Cx43) into glutamic acid (E) or alanine (A) residues.

162 o additional amino acids (tryptophan (W) and glutamic acid (E)) at the C-terminus of the mature ligan

163 A glutamic acid (E)-to-glycine (G) difference at position

164 protein depends on the protonation state of glutamic acid E163 (Ci1), one of the counterions of the

165 e show that a single hydrogen bond between a glutamic acid (E90) and an asparagine (N258) residue suf

166 e engaged, despite the lack of aspartic acid/glutamic acid encoded in the mouse repertoire.

167 uvignon, the light body of Xinomavro and the glutamic acid for Malvasia.

168 line for enamine formation on one side and a glutamic acid for nitronate protonation on the other sid

169 for Ser2 and/or Ser7 and the phosphomimetic glutamic acid for Ser7.

170 Substitution of glutamic acid for tyrosine between the Syk SH2 domains (

171 /pvdN double mutant produced exclusively the glutamic acid form of pyoverdine.

172 The peptide, which contains a photocaged glutamic acid, forms a solid-like gel in a syringe and c

173 the capabilities is demonstrated by mapping glutamic acid from a cryosectioned chicken breast with a

174 This mutation ('DeltaE') removes a single glutamic acid from the encoded protein, torsinA.

175 Poly-gamma-glutamic acid (gamma-PGA) is an important biochemical pr

176 e pgsBCA cluster (responsible for poly-gamma-glutamic acid (gamma-PGA) synthesis), were intentionally

177 ydroxyethyl methacrylate modified poly(gamma-glutamic acid) (gamma-PGA-HEMA), generating hybrid HRP@g

178 Four of them contained a gamma-carboxyl glutamic acid (Gla) domain, a calcium-binding module, an

179 Acidic amino acids, aspartic acid (Asp) and glutamic acid (Glu) can enhance the solubility of many p

180 ve methods for measuring glutamine (Gln) and glutamic acid (Glu) in cell cultures and other biologica

181 Plasma levels of glutamic acid (GLU), glutamine, glycine, proline (PRO),

182 of an unusually located and highly conserved glutamic acid (Glu-176) within the beta3 transmembrane r

183 the source (phenylalanine, Phe) and trophic (glutamic acid, Glu) AAs were 4.1 (muscle) and 5.4 (red b

184 n the soluble structure that comprised three glutamic acids (Glu92, Glu94, and Glu97) that we hypothe

185 xidase (GmOx) microelectrode for measuring l-glutamic acid (GluA) in oxygen-depleted conditions, whic

186 spartic acid, cystathionine, total cysteine, glutamic acid, glutamine, glycine, histidine, total homo

187 amino acids, aspartic acid/asparagine (Asx), glutamic acid/glutamine and alanine are positively corre

188 rtic acid (IAA-Asp) and indole-3-acetic acid glutamic acid (IAA-Glu) of 438- and 240-fold, respective

189 rus, cancer, human papillomavirus, dopamine, glutamic acid, IgG, IgE, uric acid, ascorbic acid, acetl

190 Several studies have advocated the role of glutamic acid in cancer therapy.

191 transamination of the three acids to produce glutamic acid in cancerous cells.

192 rearrangements that expressed aspartic acid/glutamic acid in CDR L2.

193 he E2 envelope glycoprotein (lysine in SFV4, glutamic acid in SFV6).

194 Replacement of a glutamic acid in the central gate with a positively char

195 Importantly, determination of free glutamic acid in the daily diet could also prevent vario

196 Point mutation of either glutamic acid in the Galpha13-binding (767)EKE motif in

197 essive tumors, drives the protonation of the glutamic acids in ATRAM, leading to the membrane translo

198 Interaction between three glutamic acids in the N-terminal domain of RsbR and the

199 The oral introduction of glutamic acid increased virus acquisition by mosquitoes

200 2, one cancer-derived ECRG2 mutant harboring glutamic acid instead of valine at position 30 (V30E) fa

201 The data suggest that glutamic acid is a nitrogen acceptor while alanine, aspa

202 he common C-terminal epitope of neuropeptide glutamic acid-isoleucine/alpha-melanocyte-stimulating ho

203 Natural mutations such as lysine 255 to glutamic acid (K to E), threonine 259 to isoleucine (T t

204 replacing this lysine with alanine (K265A), glutamic acid (K265E) or glutamine (K265Q), and the func

205 les were prepared by self-assembly of poly(L-glutamic acid-L-tyrosine) co-polymer with hematoporphyri

206 Cytoplasmic localization of proline, glutamic acid, leucine-rich protein 1 (PELP1) is observe

207 Here, we examined the role of non-glutamic acid-leucine-arginine CXC chemokine CXCL9 for T

208 side chains amino acids that were aspartate, glutamic acid, lysine and tyrosine on the negative side

209 n sources (L-Asparagine, L-Aspartic Acid, L- Glutamic Acid, m- Erythritol, D-Melezitose, D-Sorbitol)

210 t was replaced with either phospho-mimicking glutamic acids (mdxS3E) or nonphosphorylatable alanines

211 red 35 intracellular metabolites involved in glutamic acid metabolism and the gamma-glutamyl cycle in

212 eight pathways, including D-glutamine and D-glutamic acid metabolism; linoleic acid metabolism; alph

213 The hydration number of the glutamic acid molecule also fluctuates due to the rapid

214 uration, the average hydration number of the glutamic acid molecule decreases and can reach an asympt

215 ylalanine mutant E2 Y138F and phosphomimetic glutamic acid mutant Y138E.

216 In 09HA_mut, a lysine-to-glutamic-acid mutation leads to the loss of both salt br

217 transmitters glutamate and N-acetyl-aspartyl-glutamic acid (NAAG) and their precursor glutamine.

218 ations involved replacements by glutamine or glutamic acid of E2 glycoprotein amino acids in the acid

219 form the active site, by the new N-terminal glutamic acid of mature SplB is observed.

220 sp70EEVD was restored upon substitution of a glutamic acid of the J-domain.

221 er for A(3)R binders, when it was mutated to glutamic acid or alanine, the activity of IB-MECA increa

222 mug/mL histidine (p < 0.001), 100 mug/mL of glutamic acid (p < 0.05) and 200 mug/mL of glutamic acid

223 activation is reversed by the removal of the glutamic acid penultimate to the tyrosine.

224 tilayers ~700nm thick fabricated from poly-l-glutamic acid (PGA) and poly-l-lysine (PLL) can be loade

225 The poly-gamma-glutamic acid (PGA) capsule produced by Bacillus anthrac

226 A skin prick test for poly-gamma-glutamic acid (PGA) which is a component of jellyfish st

227 terized a pH-responsive biodegradable poly-L-glutamic acid (PGA)-fluocinolone acetonide (FLUO) conjug

228 eimer's disease, covalently linked to poly-l-glutamic acid (PGA).

229 hybrid hydrogels consisting of a poly(gamma-glutamic acid) polymer network physically cross-linked v

230 is work, we demonstrate that proline-proline-glutamic acid (PPE)17 protein of Mycobacterium tuberculo

231 nts in complex with L-aspartic acid versus L-glutamic acid provide insights into their differential s

232 acids and thiol precursors (especially with glutamic acid, r <= -0.73) rather than free thiols.

233 acid substitutions at this highly conserved glutamic acid residue and illustrates the value of syste

234 found that transient protonation changes of glutamic acid residue E141 and, most notably, arginine R

235 ous missense substitutions in the paralogous glutamic acid residue in TWIST2 (p.Glu75Ala, p.Glu75Gln

236 , and a strictly conserved fluorophore-bound glutamic acid residue is converted to a range of variant

237 17Val and p.Glu117Gly) at a highly conserved glutamic acid residue located in the basic DNA binding d

238 th a constitutively phosphorylated mimicking glutamic acid residue or a phosphorylation-dead mimickin

239 ing a calcium ion-binding site and chelating glutamic acid residue that mediate the formation of HC.T

240 304 was replaced with either an alanine or a glutamic acid residue was also affected.

241 enesis of any of the two conserved catalytic glutamic acid residues (Glu(200) and Glu(414)) of the ac

242 by a central tryptophan flanked by aspartic/glutamic acid residues (W-acidic).

243 Interestingly, introduction of three glutamic acid residues alone was not sufficient to estab

244 ned oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the N-

245 arboxylic groups of various key aspartic and glutamic acid residues by monitoring their C=O stretchin

246 Three glutamic acid residues in epsin UIM were found to intera

247 ouble dehydration and decarboxylation of two glutamic acid residues in the 30-residue precursor PaaP.

248 etween histidine 64 in CAII and a cluster of glutamic acid residues in the C terminus of the transpor

249 of different species with varying numbers of glutamic acid residues in the side chain ranging from 12

250 lanine, arginine, glycine, aspartic acid and glutamic acid residues represented the major amino acids

251 Notably, the glutamic acid residues were not solely gamma-linked, as

252 Replacing a cluster of glutamic acid residues with a glutamine-rich motif on th

253 ted by the gamma-carboxylase (GGCX) on three glutamic acid residues, a cellular process requiring red

254 Adding NLS, replacing aspartic acid by glutamic acid residues, or changing the l- to d-aspartic

255 rod cGMP-gated cation channel and associated glutamic acid rich proteins (GARPs) are required for pho

256 dominant negative termed A-ZIP53 that has a glutamic acid-rich amphipathic peptide sequence attached

257 ghly-diverged structure consisting of a long glutamic acid-rich C-terminal extension of ~70 residues

258 screening strategy to identify P falciparum glutamic acid-rich protein (PfGARP) as a secreted ligand

259 overy of Src homology 3 (SH3) domain-binding glutamic acid-rich-like protein (SH3BGRL), a novel c-Src

260 arum parasites(2), we identify P. falciparum glutamic-acid-rich protein (PfGARP) as a parasite antige

261 In animal experiments knocking in a glutamic acid (S1530E) in DEPDC5, a phospho mimic, in tu

262 Glutamic acid, serine, and glycine concentrations are kn

263 Mechanically, a typical proline, glutamic acid, serine, and threonine motif specifically

264 appaBalpha C-terminal PEST (rich in proline, glutamic acid, serine, and threonine residues) sequence

265 ontains PEST sequences (enriched in proline, glutamic acid, serine, and threonine) and is normally su

266 ein tyrosine phosphatases from the proline-, glutamic acid-, serine- and threonine-rich (PEST) family

267 mutations causing deletions of the proline-, glutamic acid-, serine-, and threonine-rich (PEST) domai

268 y, p66 with Thr(206) and Ser(213) mutated to glutamic acid showed a gain-of-function phenotype with s

269 ysines in UCP1 to acyl-mimetic glutamine and glutamic acid significantly decreases its stability and

270 were prepared using amphiphilic PEG-b-poly(L-glutamic acid)/SN38 conjugates and subsequently loaded w

271 Charge reversal by glutamic acid substitution at Arg-I or Arg-II has opposi

272 The simulations also show why glutamic acid substitution at either serine does not con

273 However, lysine to glutamic acid substitutions at the KTKEGV repeat domain

274 The alanine and glutamic acid substitutions reduced actin-activated ATPa

275 s, and evolutionarily conserved, whereas the glutamic acids surrounding phosphosites significantly de

276 ociation interfaces and a putative catalytic glutamic acid that is conserved in both bacterial TIR NA

277 amily contains an unnatural 4,4-disubstitued glutamic acid, the synthesis of which provides a key cha

278 cation as a transformation of the N-terminal glutamic acid to a succinamide.

279 to be responsible for the conversion of the glutamic acid to alpha-ketoglutaric acid.

280 olism as it catalyses the decarboxylation of glutamic acid to form GABA.

281 GLUL encoding glutamine synthase, converting glutamic acid to glutamine.

282 A glutamic acid to lysine (E40K) residue substitution in s

283 two amino acid mutations in the PB2 protein (glutamic acid to lysine at position 627 and aspartic aci

284 n of histone 3 lysine 36 (H3K36), exhibits a glutamic acid to lysine mutation at residue 1099 (E1099K

285 an internal proton transfer from a conserved glutamic acid to the proton-loading site of the pump.

286 a revealed three novel mutations including a glutamic acid to valine substitution (E1338D), a glutami

287 nin still can form pores, but mutating these glutamic acids to glutamines rendered the toxin pH-insen

288 Host-adaptive mutations, particularly a glutamic-acid-to-lysine mutation at amino acid residue 6

289 ulting variant, which has cysteine-histidine-glutamic acid triads on each helix, hydrolyses p-nitroph

290 MA-targeted hybrid tracers were synthesized: glutamic acid-urea-lysine (EuK)-Cy5-mas(3), EuK-(SO(3))C

291 Rather, amino acids alanine, phenylalanine, glutamic acid, valine, and leucine increased in samples

292 atural language (NL) largely untapped (e.g. 'glutamic acid was substituted by valine at residue 6').

293 the S4-S5 helix of the chicken receptor to a glutamic acid was sufficient to endow it with capsaicin

294 ythro-beta-d-methylaspartic acid and gamma-d-glutamic acid were key for an isomerization-free synthes

295 s anthracis is composed entirely of d-isomer glutamic acid, whereas nonpathogenic Bacillus species pr

296 n metabolisms, glutathione, guanosine, and L-glutamic acid, which are implicated in protection agains

297 Molecular modeling analysis reveals that the glutamic acid, which is negatively charged, interacts wi

298 Structural analysis revealed that this key glutamic acid, which is not present in Ydj1, forms a sal

299 ne could effectively extract about 3.5 mg of glutamic acid with 95% enantiomeric excess in 24 h.

300 ated either to the potential phospho-mimetic glutamic acid (Y102E) or to the nonphosphorylated homolo