ライフサイエンスコーパス: glutamyl-tRNA synthetase

1 glutamate is ligated to its cognate tRNA by glutamyl-tRNA synthetase.

2 d by a single eukaryotic-type discriminating glutamyl-tRNA synthetase.

3 kinase, sucrose-phosphate synthase (SPS) and glutamyl-tRNA synthetase.

4 tRNA is not a substrate for the H. volcanii glutamyl-tRNA synthetase.

5 inhibits translation via phosphorylation of glutamyl-tRNA synthetase.

6 f this enzyme from the eukaryotic lineage of glutamyl-tRNA synthetases.

7 5 putatively encodes an homolog of bacterial glutamyl-tRNA synthetases.

8 re of the chicken IARS1 UNE-I complexed with glutamyl-tRNA synthetase 1 (EARS1).

9 First, glutamyl-tRNA synthetase activates glutamate by ligating

10 e for essentially all of the glutaminyl- and glutamyl-tRNA synthetase activity detected in both the c

11 and asparaginyl-tRNA synthetase evolved from glutamyl-tRNA synthetase and aspartyl-tRNA synthetase, r

12 ase and utilize a two-step pathway involving glutamyl-tRNA synthetase and glutamine amidotransferase

13 n the linker region that joins the catalytic glutamyl-tRNA synthetase and prolyl-tRNA synthetase doma

14 th the multisynthetase complex, E205G in the glutamyl-tRNA synthetase (ERS) region of EPRS is defecti

15 We identified three aaRSs, the glutamyl-tRNA synthetase (ERS), glutaminyl-tRNA syntheta

16 t-transfer states with charged tRNA bound to glutamyl-tRNA synthetase from Thermus thermophilus (Glu-

17 E. coli HipA inactivates the glutamyl-tRNA synthetase GltX, which inhibits translatio

18 persister protein A) kinase, which inhibits glutamyl tRNA synthetase (GltX).

19 The glutamyl-tRNA synthetase (gltX) gene from Pseudomonas ae

20 ic screen reveals that the overexpression of glutamyl-tRNA synthetase (GltX) suppresses the toxicity

21 (Gln) is produced via an indirect pathway: a glutamyl-tRNA synthetase (GluRS) first attaches glutamat

22 To date, only glutamyl-tRNA synthetase (GluRS) has been found to conta

23 ort the characterization of a well conserved glutamyl-tRNA synthetase (GluRS) paralog (YadB in Escher

24 in early eukaryotes from a nondiscriminating glutamyl-tRNA synthetase (GluRS) that aminoacylates both

25 nsplanting a conserved arginine residue from glutamyl-tRNA synthetase (GluRS) to glutaminyl-tRNA synt

26 the presence of AsnRS and GlnRS, as well as glutamyl-tRNA synthetase (GluRS), a discriminating and a

27 ved from the archaeal-type nondiscriminating glutamyl-tRNA synthetase (GluRS), an enzyme with relaxed

28 oshii class I LysRS (LysRS1) and homology to glutamyl-tRNA synthetase (GluRS), residues implicated in

29 Gln) is initially acylated with glutamate by glutamyl-tRNA synthetase (GluRS), then the glutamate moi

30 netic analyses predict that GlnRS arose from glutamyl-tRNA synthetase (GluRS), via gene duplication w

31 ced with the corresponding residues of human glutamyl-tRNA synthetase (GluRS).

32 first enzyme in this pathway, the apicoplast glutamyl-tRNA synthetase (GluRS).

33 ntaining the anchoring protein Arc1p and the glutamyl-tRNA synthetase (GluRS).

34 ompare the signaling pathways in a bacterial glutamyl-tRNA synthetase (GluRS):tRNA(Glu) and an archae

35 m Helicobacter pylori utilizes two essential glutamyl-tRNA synthetases (GluRS1 and GluRS2).

36 RNA synthetase (GlnRS) but has two divergent glutamyl-tRNA synthetases: GluRS1 and GluRS2.

37 ng protein that forms a ternary complex with glutamyl-tRNA synthetase (GluRSc) and methionyl-tRNA syn

38 Glutamyl-tRNA synthetases (GluRSs) occur in two types, t

39 rk identifies genes encoding glutaminyl- and glutamyl-tRNA synthetase in the closely related organism

40 The glutamyl-tRNA synthetase is from the achaebacterium Pyro

41 in a two-step process; a non-discriminating glutamyl-tRNA synthetase (ND-GluRS) forms Glu-tRNA(Gln),

42 lation pathway utilizes a non-discriminating glutamyl-tRNA synthetase to synthesize Glu-tRNA(Gln) and

43 C. trachomatis aspartyl-tRNA synthetase and glutamyl-tRNA synthetase were shown to be non-discrimina