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1 ette protein C1, which effluxes arsenic as a glutathione conjugate.
2  cochromatographed with a synthetic atrazine-glutathione conjugate.
3  of metal thiolates, including the Pentostam-glutathione conjugate.
4          Hg is eliminated from the body as a glutathione conjugate.
5 ssary only for the toxicity of the cisplatin-glutathione-conjugate.
6 ain and transports substrates in the form of glutathione conjugates.
7 pid peroxidation-derived aldehydes and their glutathione conjugates.
8 , and greater MRP1-mediated efflux of NO2-OA-glutathione conjugates.
9  transporter of doxorubicin (DOX) as well as glutathione conjugates.
10 openoate and two mercapturate derivatives of glutathione conjugates.
11 ding site for hydrophobic molecules or their glutathione conjugates.
12 olves the formation and active efflux of its glutathione conjugate, 15-d-PGJ(2)-SG.
13 iol 17-beta-D-glucuronide (E(2)17betaG), the glutathione conjugates 2,4-dinitrophenyl S-glutathione (
14           However, the much larger aflatoxin-glutathione conjugate, 8, 9-dihydro-8-(S-glutathionyl)-9
15         Recombinant TaGSTFs were assayed for glutathione conjugating activity towards xenobiotics inc
16 nitrobenzene (CDNB), but has relatively high glutathione-conjugating activity for 4-hydroxynonenal (4
17 ration calorimetry with a representative bis-glutathione conjugate and a monofunctional reference com
18 ne upon an electrophilic substrate to form a glutathione conjugate and contain a single glutathione b
19 te covalent attachment of a haloenol lactone-glutathione conjugate and suggest that an ester forms be
20 the Y9F substitution on binding affinity for glutathione conjugates and on rates of the order-disorde
21 movement of solute allocrites, which include glutathione conjugates and several natural product antin
22 gnal transduction, can catalyze transport of glutathione conjugates and xenobiotics, and may contribu
23 propyl atrazine, desethyl atrazine, atrazine-glutathione conjugate, and atrazine-mercapturate, using
24 binding domains-the first is a series of bis-glutathione conjugates, and the second is a series of co
25 t with broad substrate specificity, the drug glutathione conjugate APA-SG, oxidized glutathione, the
26                Leukotriene (LT) C4 and other glutathione conjugates are synthesized intracellularly a
27 thione, suggesting that the substrate is the glutathione conjugate, As(GS)3.
28 phytochelatin synthesis and deglycination of glutathione conjugates, as catalytic-site mutants of PCS
29 ic sequestration of these ligands, and their glutathione conjugates, away from their nuclear target,
30 athione reveals a third binding site for the glutathione conjugate besides the two in the active site
31 (Kd) of 59 +/- 17 microM while the aflatoxin-glutathione conjugate bound the enzyme with a Kd of 0.86
32 s are not only competent in the transport of glutathione conjugates but also folate monoglutamates an
33 y for optimal transport of anthracycline and glutathione conjugates by RLIP76, and that this peptide
34 en widely used for the in vitro screening of glutathione conjugates derived from reactive metabolites
35             From the export of the menadione-glutathione conjugate detected at a 1-microm-diameter el
36                                 By using the glutathione-conjugating dye monochlorobimane, in combina
37 PGJ(2), 15-d-PGJ(2)-SG, is formed and if the glutathione conjugate efflux pumps, MRP1 and MRP3, could
38 pastoris, exhibited low lipid peroxidase and glutathione-conjugating enzymatic activities but high he
39 ts comparing the kinetics of MLP- versus CHB-glutathione conjugate: formation, product inhibition of
40      Branched derivatives of acrolein or its glutathione conjugate (GS-propanal) were, however, reduc
41 ress-protective multispecific transporter of glutathione conjugates (GS-E) and xenobiotic toxins.
42      The equilibrium binding affinity of the glutathione conjugate, GS-NBD (NBD-Cl, 7-chloro-4-nitrob
43 egulation and modulation of the transport of glutathione conjugates in seeds of desi and kabuli chick
44 hese results indicate that MRP can transport glutathione conjugates in vitro and in living cells and
45 sociated and cytoplasmic protein which binds glutathione conjugates including LTC4.
46 f nasal microsomal DCBN metabolites and DCBN-glutathione conjugates indicated that the major reactive
47       Inhibitors acting via the formation of glutathione conjugates induced a very pronounced stabili
48 the canalicular transport of glutathione and glutathione conjugates is deficient, although dibutyryl
49 oposide, and vincristine, as well as for the glutathione conjugate leukotriene C4 (LTC4).
50  was rapidly and quantitatively converted to glutathione conjugates (LNO(2)-SG) via Michael addition.
51 a cysteine-conjugated metabolite) and M13 (a glutathione-conjugated metabolite), against macrophage c
52  12-D(3)NVP vs NVP, while glucuronidated and glutathione-conjugated metabolites increased with 12-D(3
53 iate vacuolar accumulation of the quorescent glutathione-conjugate, monochlorobimane-GS.
54 e accumulation of the harderoporphyrin(ogen)-glutathione conjugate observed in the expression studies
55 ent and was associated with formation of the glutathione conjugate of 15-d-PGJ(2), 15-d-PGJ(2)-SG, an
56                        We examined whether a glutathione conjugate of 15-d-PGJ(2), 15-d-PGJ(2)-SG, is
57  contrast, ATP-dependent accumulation of the glutathione conjugate of a chlorsulfuron analog, chlorim
58 f ZmGSTU1 led to the accumulation of a novel glutathione conjugate of harderoporphyrin(ogen) (2,7,12,
59 d one of its putative metabolites, i.e., the glutathione conjugate of p-XSC (p-XSe-SG), and determine
60 act heart, AR catalyzes the reduction of the glutathione conjugate of the lipid peroxidation product
61 s not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a nove
62 tic efficiency of AR in the reduction of the glutathione conjugates of acrolein, trans-2-hexenal, tra
63 ductase (AR) reduces cytotoxic aldehydes and glutathione conjugates of aldehydes derived from lipid p
64 h a possible role of AR in the metabolism of glutathione conjugates of aldehydes.
65                               Measurement of glutathione conjugates of BPDE indicated that the total
66 an important role of AR in the metabolism of glutathione conjugates of endogenous and xenobiotic alde
67 ed to the heart, was identified to be due to glutathione conjugates of HNE.
68 These results raise the possibility that the glutathione conjugates of lipid peroxidation products ar
69                          Accumulation of the glutathione-conjugate of CDNB, DNP-SG, and of doxorubici
70 tes are generally amphiphilic anions such as glutathione conjugates or require the presence of physio
71 rate or route of metabolism, particularly to glutathione conjugates, or in the levels of covalent bin
72  antibacterial activity of antibiotic-loaded glutathione-conjugated poly(ethylene glycol) hydrogels (
73 s the reduction of lipid aldehydes and their glutathione conjugates, prevents human colon cancer cell
74 ne transporter catalyzed the accumulation of glutathione-conjugated probes, and another transported p
75 ated transport demonstrate that the vacuolar glutathione conjugate pump of yeast bears a strong mecha
76        These results indicate that MRP6 is a glutathione conjugate pump that is able to confer low le
77 of menadione and that the efflux through the glutathione-conjugate pump was at least an order of magn
78 ted by reduced and oxidized glutathione, the glutathione conjugates S-(p-azidophenacyl)-glutathione (
79                          Whereas SFN and its glutathione conjugate (SFN-GSH) had little or no effect,
80      Apocrine metabolism produces odorless S-glutathione conjugate that is transferred by ABCC11 tran
81 quinone is attacked by glutathione to form a glutathione conjugate that, in the absence of Cys13, dec
82 ch could increase the formation of cisplatin-glutathione conjugates that may be metabolized to toxic
83 is activation begins with the formation of a glutathione-conjugate that is metabolized to a cysteinyl
84 s to menadione and detecting the menadione-S-glutathione conjugate (thiodione) that is formed during
85 The Yeast Cadmium Factor 1 (Ycf1) transports glutathione conjugated to toxic heavy metals including C
86 te, for the first time, efficient binding of glutathione conjugates to an aldo-keto reductase.
87 (p-nitrobenzyl glutathione and the aflatoxin-glutathione conjugate) to mouse glutathione S-transferas
88            Here, we show marked reduction in glutathione conjugate transport capacity and stepwise in
89 t in human erythrocytes, its relationship to glutathione conjugate transport, and possible mediation
90 elationship between this process and organic glutathione-conjugate transport are known.
91                It represents the predominant glutathione-conjugate transporter in cells, and our prev
92                         RLIP76 (RALBP1) is a glutathione-conjugate transporter that is a critical com
93 treated with antibodies directed against the glutathione conjugate transporters RLIP76 (Ral-binding p
94  injury but did induce RNA expression of the glutathione-conjugate transporters encoded by AtMRP1, At
95  H(+) antiporter, whereas vanadate-sensitive glutathione conjugate uptake is mediated by an ATP-bindi
96  protein, or sequester it in vacuoles as the glutathione conjugate using Ycf1p, an ABC transporter.
97 atin from glutathione and the degradation of glutathione conjugates via peptidase activity.
98                            Both 4ONE and its glutathione conjugate were found to be substrates for CR
99 olished the mitogenic effects of HNE and its glutathione conjugates, whereas ablation of RLIP76 using
100 mitogenic effects of HNE are mediated by its glutathione conjugate, which has to be reduced by aldose
101 st glutathione is involved in formation of a glutathione conjugate, while the second is involved in t
102 lutathione S-transferases (GSTs), which form glutathione conjugates with lipid peroxidation products

 
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