ライフサイエンスコーパス: glutathione transferase

1 s 1 (ABA-1), Asc l 3 (tropomyosin) and GST (glutathione transferase).

2 rium lacks yliJ, a gene encoding a predicted glutathione transferase.

3 e design of selective inhibitors of class pi glutathione transferases.

4 ccharomyces cerevisiae genes, GTT1 and GTT2 (glutathione transferase 1 and 2), coding for functional

5 Microsomal glutathione transferase-1 (MGST1) is a trimeric, membran

6 The detoxication enzyme glutathione transferase A1-1 (GSTA1-1), exploits a molte

7 functionally necessary alpha-helix in human glutathione transferase A1-1 (hGSTA1-1).

8 e C-terminal region of the human class alpha glutathione transferase A1-1 have been investigated with

9 teroid Delta(5)-androstene-3,17-dione by the glutathione transferase A3-3 in mammals was investigated

10 he Marcus formalism indicates that the human glutathione transferase A3-3 lowers the intrinsic kineti

11 Conjugation to glutathione (GSH) by glutathione transferase A4-4 (GSTA4-4) is a major route

12 colon mucosal biopsies revealed increases in glutathione transferase activity at the lower dose level

13 This glutathione transferase activity of MMACHC is reminiscen

14 CblC is the first example of an enzyme with glutathione transferase activity that has a sequence and

15 ow epoxide hydrolase activity and even lower glutathione transferase activity toward 1 and does not c

16 er supplemented with reduced glutathione for glutathione transferase activity.

17 Here, we show that glutathione transferase alpha4 (GSTA4), a member of the

18 CblC, a B12 trafficking protein, exhibits glutathione transferase and reductive decyanase activiti

19 mportant in the monomer-dimer equilibrium of glutathione transferase and that, although GST M1-1 may

20 The extracts induced glutathione transferases and heat shock protein 70, sugg

21 ajor enzyme families- the carboxylesterases, glutathione transferases, and cytochrome P450s-that are

22 l morphological differences, upregulation of glutathione transferases, and SKN-1-dependent oxidative

23 s (GS- HQRs) are a newly identified group of glutathione transferases, and they are widely distribute

24 cytochromes P450 (P450s), sulfotransferases, glutathione transferases, and UDP-glucuronosyltransferas

25 Glutathione transferases are a multigene family of prote

26 Glutathione transferases are detoxification enzymes that

27 elated to the FosA class of Mn(2+)-dependent glutathione transferases but with a preference for Mg(2+

28 Equine glutathione transferase catalyzed 1,6 addition of GSH to

29 he low expression allele may be deficient in glutathione transferase catalyzed biological functions.

30 The fact that pi-glutathione transferase catalyzes the acyl-interchange r

31 channel 2 (CLIC2) protein is a member of the glutathione transferase class of proteins.

32 Glutathione transferases comprise a large family of cell

33 anscription factor CsMYB75 and phi (F) class glutathione transferase CsGSTF1 as being associated with

34 The cytosolic glutathione transferase (cytGST) superfamily comprises m

35 have characterized a Drosophila melanogaster glutathione transferase (DmGSTE6) which has activity tow

36 otective enzymes such as the Phase II enzyme glutathione transferase (EC 2.5.1.18).

37 ction of phase 2 detoxication enzymes [e.g., glutathione transferases, epoxide hydrolase, NAD(P)H: qu

38 perfamily, we identified two novel mammalian glutathione transferase families that were recognized pr

39 nd identification of a thiol reductase and a glutathione transferase from soybean seedling cotyledons

40 The crystal structure of the sigma class glutathione transferase from squid digestive gland in co

41 is suppression of ROS was independent of the glutathione transferase function of LANCL1.

42 MAP4 was expressed in Escherichia coli as a glutathione transferase fusion protein and was injected

43 ombinant HGE-44, expressed and purified as a glutathione transferase fusion protein, was used as the

44 mouse and human nardilysin were expressed as glutathione transferase fusion proteins.

45 Induction of hepatic glutathione transferase genes and elevated total glutath

46 The specificity of human glutathione transferase (GST) A1-1 is drastically altere

47 Glutathione transferase (GST) A4-4 is a key component in

48 ssion in Escherichia coli of a tau (U) class glutathione transferase (GST) from maize (Zea mays L.),

49 the ability of purified arrestins to bind to glutathione transferase (GST) fusion proteins containing

50 Arrestin 3 bound to glutathione transferase (GST) fusion proteins of the D(2

51 s redox homeostasis via direct regulation of glutathione transferase (GST) genes.

52 Negative cooperativity occurs in human glutathione transferase (GST) GSTP1-1 when it binds and

53 The phase II detoxification system glutathione transferase (GST) is associated with the est

54 ne (GSNO)-mediated transnitrosation of human glutathione transferase (GST) P1-1, a major detoxificati

55 Here, we probed the role of glutathione transferase (GST) P1-1, an antiapoptotic pro

56 vered small protein distantly related to the glutathione transferase (GST) structural family, is high

57 m uroporphyrinogen and the induction of a mu-glutathione transferase (GST) were consistent with the o

58 greatly elevated levels of a specific type I glutathione transferase (GST), termed AmGST2, but simila

59 Since the 1960s, the multiple forms of glutathione transferase (GST), the GSTome, were isolated

60 A that V(max) was stimulated 3- to 4-fold by glutathione transferase (GST)-Galpha(12) with little eff

61 h huntingtin and P150 selectively bound to a glutathione transferase (GST)-HAP1 fusion protein.

62 H) is added to a mixture containing RBCs and glutathione transferase (GST).

63 Here, two structurally similar glutathione transferase (GST, glutathione S-transferase)

64 cytochrome P450s (CYP), esterases (EST), or glutathione transferases (GST) and at 12 previously mapp

65 Theta class glutathione transferases (GST) from various species exhi

66 A1, we created a bacterial fusion protein of glutathione-transferase (GST) and BRCA1 zinc finger doma

67 ste perception, we demonstrate that salivary glutathione transferases (GSTA1 and GSTP1) can metaboliz

68 his study we discovered that the Omega class glutathione transferase GSTO1-1 plays a significant role

69 s linked to the overexpression of a pi class glutathione transferase (GSTP1), which has both detoxifi

70 ption-PCR was used to measure mRNA levels of glutathione transferases (GSTs) and glutathione peroxida

71 Glutathione transferases (GSTs) are protection enzymes c

72 Glutathione transferases (GSTs) are ubiquitous scavenger

73 The glutathione transferases (GSTs) from maize (Zea mays L.)

74 Six phi (F) class glutathione transferases (GSTs) were cloned from bread w

75 Glutathione transferases (GSTs), a superfamily of enzyme

76 Here, we demonstrate the importance of two glutathione transferases (GSTs), GST-U24 and GST-U25, fr

77 es, indicating partial DON detoxification by glutathione transferases (GSTs).

78 FRET-FLIM and co-IP demonstrated that the glutathione transferase GSTU4, which is coexpressed with

79 erse superfamilies (amidohydrolase, enolase, glutathione transferase, haloalkanoic acid dehalogenase,

80 Continuing work with glutathione transferases has resulted in the identificat

81 e transferase (rGSTT2) and the human theta 1 glutathione transferase (hGSTT1) genes (63% DNA sequence

82 As glutathione transferases in other plants are known to ac

83 SH) bound in the active site of the class mu glutathione transferase M1-1 from rat involves a hydroge

84 Although rat glutathione transferase M1-1 is crystallized as a homodi

85 CYP2D6, CYP2E1, NAD(P)H-menadione reductase, glutathione transferases M1 and T1, and N-acetyltransfer

86 Phase 2 enzymes (e.g., glutathione transferases, NAD(P)H:quinone reductase) and

87 Induction of phase 2 enzymes (e.g., glutathione transferases, NAD(P)H:quinone reductase, glu

88 Glutathione transferase Omega 1 (GSTO1-1) is an atypical

89 Human glutathione transferase pi (GST pi) has been crystallize

90 Glutathione transferase pi (GSTP) catalyzes the detoxifi

91 Glutathione transferase Pi (GSTP) is commonly overexpres

92 These regions are attributed to the glutathione transferase portion of the fusion protein be

93 Here, the glutathione transferase pull-down assay was used to inve

94 Glutathione transferase pull-down assays and site-direct

95 Glutathione transferase pulldown assays demonstrate that

96 highly reactive cob(I)alamin product of the glutathione transferase reaction.

97 Glutathione transferase rGSTM1-1 catalyzes the addition

98 tructed such a library using the rat theta 2 glutathione transferase (rGSTT2) and the human theta 1 g

99 Using query sequences from known mammalian glutathione transferase subfamilies, we identified new c

100 Using query sequences from the glutathione transferase superfamily, we identified two n

101 Unlike many glutathione transferases, the reaction catalysed by MPI

102 A marked increase in serum alpha-glutathione transferase, TNF-alpha, IL-6, IL-10, MCP-1,

103 down assay, with cpSRP43 or cpSRP54 fused to glutathione-transferase, to study interactions between c

104 none reductases (GS-HQRs) are a new class of glutathione transferases, widely present in bacteria, ha

105 ification of fragments of carbon-13-enriched glutathione transferase within a complex mixture of unla

106 MAAI is also known as glutathione transferase zeta (GSTZ1).