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1 structural modeling of the SARS-CoV-2 spike glycoprotein.
2 erogeneity impacts the antigenicity of the S glycoprotein.
3 izing humoral immune response, the spike (S) glycoprotein.
4 g cathepsin-mediated processing of the Ebola glycoprotein.
5 n identification at a low microgram level of glycoprotein.
6 5 DENV3 TS mAbs recognizing the envelope (E) glycoprotein.
7 lybasic furin cleavage site in its spike (S) glycoprotein.
8 ERINC5 with remodeling of the HIV-1 envelope glycoprotein.
9 ngaging the receptor-binding domain of the S glycoprotein.
10 t-pass metabolism, and efficient efflux by P-glycoprotein.
11 g irreversible conformational changes in the glycoprotein.
12 llular immune responses to Ebolavirus (EBOV) glycoprotein.
13 taneous interaction between all three of the glycoproteins.
14 thesis and quantitative evaluation of intact glycoproteins.
15 diverse glycans on cell surface and secreted glycoproteins.
16 t glycopeptides (IGPs) derived from N-linked glycoproteins.
17 n of sulfated glycosaminoglycans and charged glycoproteins.
18 sitioned to match the C termini of the viral glycoproteins.
19 y for antibodies reactive with Nipah G and F glycoproteins.
20 ased intact glycopeptide characterization of glycoproteins.
21 uses distinct receptors and receptor-binding glycoproteins.
22 e group of cell surface- and wall-associated glycoproteins.
23 from the OpeRATOR digestion of four known O-glycoproteins.
24 ls, the dopamine D2 receptor, and complement glycoproteins.
25 nvestigated the role of leucine-rich alpha-2-glycoprotein 1 (LRG1) in normal and diabetic wound heali
28 GT8, an engineered outer domain of the HIV-1 glycoprotein-120, on DNA origami nanoparticles to system
31 vivo. Here, we investigated synaptic vesicle glycoprotein 2A (SV2A) levels and their relationship to
32 CB-J, a radioligand for the synaptic vesicle glycoprotein 2A (SV2A), were used to study hippocampal s
33 (ND) Conclusion: The novel synaptic vesicle glycoprotein 2A tracer, (18)F-SynVesT-1, displays excell
34 oclonal antibodies that target the spike (S) glycoprotein(5), and identify several that exhibit poten
35 lactans connected to proteins which form AGP glycoprotein, a macro-molecule responsible for the emuls
36 MGAT1 (Man(5)GlcNAc(2)Asn) to accumulate on glycoproteins, a change that is detected by the lectin G
39 ecific to the extracellular virion membrane, glycoproteins A33, A34, and B5 are highly conserved amon
40 asma high-sensitivity C-reactive protein and glycoprotein acetyls at 3 consecutive antenatal time poi
41 rnal high-sensitivity C-reactive protein and glycoprotein acetyls at and across all 3 antenatal time
43 ers C-reactive protein (CRP) and alpha1-acid glycoprotein (AGP) and serum vitamin B-12 and serum and
45 and C-reactive protein (CRP) or alpha-1-acid glycoprotein (AGP) was observed: 1) exclude individuals
46 C-reactive protein (hs-CRP), and alpha1-acid glycoprotein (AGP)] for which observational associations
47 and 2 (TNFR1 and TNFR2), CD44, or alpha2-HS glycoprotein (AHSG), all of which are involved in the pa
49 one-binding globulin (SHBG) is a circulating glycoprotein and a regulator of sex hormone levels, whic
50 ion model, we sought to understand the viral glycoprotein and cellular receptor required for EBV-2 in
51 ng of immunity against the coronavirus spike glycoprotein and detail novel pathways to rapidly identi
52 unique glycosylation events belonging to 378 glycoproteins and 604 unique protein sites of glycosylat
55 is virus (rVSV) vectors expressing filovirus glycoproteins and that also contains a rVSV vector expre
56 rage was obtained for N-glycans derived from glycoproteins and tissue samples after chemical derivati
57 and provides specific immunity against Ebola glycoprotein, and is currently in phase 2 and 3 studies.
58 eRATOR is not fully active toward sialylated glycoproteins, and it has been suggested that this acidi
59 icacy at baseline, and modulation of the KEL glycoprotein antigen occurred to the same extent in the
62 ory pathway, misfolded asparagine (N)-linked glycoproteins are selectively sorted for endoplasmic ret
63 ze the glycocalyx N-glycans and O-glycans of glycoproteins, as well as intact glycolipids in parallel
65 xpressing the human cytomegalovirus antigens glycoprotein B (gB) and the 65-kD phosphoprotein (pp65),
66 silencing and the colocalization of LAMP-1, glycoprotein B (gB) of MDV, and cholesterol (filipin III
69 inst HCMV infection, and the virion envelope glycoprotein B (gB) serves as a major target of neutrali
71 In this study, we sought to improve upon the glycoprotein B protein vaccine (gB/MF59), the most effic
73 vide a way forward for developing diagnostic glycoprotein biomarkers with urine as a noninvasive biol
74 Microarrays revealed that the transmembrane glycoprotein Bone marrow stromal antigen 2 (Bst2) expres
75 erate molecular dynamics simulations of each glycoprotein both alone and interacting with one another
76 ing, revealing a physiological role for this glycoprotein, but that excess LRG1 expression in diabete
77 served reduced plasma levels of zinc-alpha-2-glycoprotein, butyrylcholinesterase, and increased level
82 t with the late endosomal/lysosomal membrane glycoprotein CLN3 (ceroid lipofuscinosis neuronal 3), wh
83 ll growth and differentiation by controlling glycoprotein clustering, signaling, and endocytosis.
84 glycosylation motif in the subunit G1 of the glycoprotein complex of Can, which is otherwise present
85 oteins including HIV-1 envelope, Lassa virus glycoprotein complex, and influenza hemagglutinin, where
86 an intracellular component of the dystrophin glycoprotein complex, directly and robustly promotes the
87 teins have defined the interaction sites for glycoprotein complexes and receptors, and have revealed
88 148, such as modulation of alternative viral glycoprotein complexes that govern the virus' ability to
89 roduction of a clinical HIV vaccine with Env glycoprotein components.IMPORTANCE HIV-1 Env protein is
90 the specific effects of SERINC5 on the HIV-1 glycoprotein conformation may be useful for designing ne
91 ingle-cycle HSV candidate vaccine deleted in glycoprotein-D (DeltagD-2) that induces ADCC provided co
92 ighamoeba infection on fluid secretion and P-glycoprotein-dependent detoxification by desert locust M
94 DC-SIGN-mediated augmentation of Ebola virus glycoprotein-driven cell entry (with IC(50) values down
95 that both host proteases can activate the S glycoprotein during the process of syncytium formation.
98 amma)-producing CD4 T cells specific for VZV glycoprotein E and all other structural and nonstructura
100 he rod-shaped structures failed to recognize glycoprotein E, the well-known binding partner of gI.
103 ally affect the activities and half-lives of glycoproteins, effects that are relevant to understandin
106 es with subtype A BG505-derived HIV envelope glycoprotein (Env) immunogens have revealed that the dom
108 n of HIV-1 Env.IMPORTANCE The HIV-1 envelope glycoprotein (Env) opens in response to receptor CD4 bin
109 erial conformational changes in the envelope glycoprotein (Env) trimer that result in the fusion of t
112 genicity of native-like recombinant envelope glycoprotein (Env) trimers based on viral sequences from
114 ction with either the myelin oligodendrocyte glycoprotein epitope MOG(35-55) or the full-length recom
117 st that HSV-1 gC protects the viral envelope glycoproteins essential for entry, including gB, by shie
119 we demonstrate that the SARS-CoV-2 spike (S) glycoprotein exhibits a high-affinity motif for binding
120 ing to extracellular pathogens, HLA class II glycoproteins, expressed by specialized antigen-presenti
121 ls, where the native glycan presentation and glycoprotein expression are preserved, have significant
123 We studied the contribution of several S glycoprotein features to these functions, focusing on th
125 otein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, reco
126 mically released from isolated cell membrane glycoproteins following N-glycan and lipid/glycolipid re
127 system will fuel the development of helminth glycoproteins for pharmaceutical applications or novel a
128 ral pseudoparticles that contain the surface glycoprotein from the pathogenic virus incorporated into
129 These pseudoparticles enter cells using the glycoprotein from the pathogenic virus, leading to a rea
130 so facilitated the novel characterization of glycoproteins from the red alga Cyanidioschyzon merolae.
131 e similar domain connectivity that resembles glycoproteins from unrelated animal-infecting viruses, s
133 F), an exceptionally large multimeric plasma glycoprotein, functions to initiate coagulation by agglu
136 ibe the crystal structure of the RSV surface glycoprotein G in complex with a broadly neutralizing hu
137 virus (VSV) recombinants expressing the RABV glycoprotein (G) demonstrated that GRP-60367 inhibits en
138 ent of the viral genome encodes two envelope glycoproteins, G(N) and G(C), which together form the en
141 or the splicing of UL44 transcripts encoding glycoprotein gC, a protein known as being essential for
143 and tetraantennary N-glycans of alpha-1-acid glycoprotein generally containing 0 or 1 alpha2-6-linked
147 us vaccine expressing the Ebola virus (EBOV) glycoprotein (GP) (rVSV-ZEBOV) was successfully used dur
148 granules, dense granule secretion machinery, glycoprotein (GP) VI, or the GPVI signaling effector pho
149 s to the immunodominant NiV receptor-binding glycoprotein (GP), and potently neutralizes NiV, indicat
154 acting with their respective viral surfaces (glycoprotein gp120 of HIV and the fivefold axis of the E
158 n gB is nonfusogenic on its own and requires glycoproteins H (gH) and L (gL) for membrane fusion, whi
163 us (HCMV) and Epstein-Barr virus (EBV) entry glycoproteins have defined the interaction sites for gly
164 dopsin-like G protein-coupled receptors, the glycoprotein hormone receptors (GPHR) have a large extra
165 e results provide insights into SARS-CoV-2 S glycoprotein-host cell interactions that likely contribu
167 port that, under flow, von Willebrand factor/glycoprotein Ibalpha-dependent platelet 'priming' induce
168 syndromes (NSTEACS) in the EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST
169 first device with consequently higher use of glycoprotein IIb/IIIa inhibitors and thrombus aspiration
173 We performed dose-response, synergism, P-glycoprotein inhibition, and pharmacokinetic studies in
174 tive mass spectrometry to map the glycan and glycoprotein interactors for galectin-3 in live human he
175 stematic optimization and evaluation using a glycoprotein interference model, the SPS/ETD approach wa
177 the case of influenza, the receptor-binding glycoprotein is the haemagglutinin (HA), and following r
179 rough structure-based design of the envelope glycoproteins is a promising route to an effective vacci
180 , a C-type lectin domain-containing membrane glycoprotein, is selectively expressed on highly activat
181 ting indicate that papilin, a poorly studied glycoprotein, is the most abundant component in the gona
184 find that targeting the BMME with P-selectin glycoprotein ligand-1 (PSGL-1)-targeted BTZ and ROCK inh
185 ichment of a mutation within UL100 (encoding glycoprotein M) and a specific truncation of glycoprotei
187 in basic protein (MBP) and myelin-associated glycoprotein (MAG) myelin proteins were markedly increas
188 elin basic protein(+)/myelin oligodendrocyte glycoprotein(+) mature oligodendrocytes with reciprocal
189 substrates and glycan substrates present on glycoproteins, measured simultaneously, affords a unique
190 binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor
192 re, we identify the germ cell specific Golgi glycoprotein MGAT4D as a protector of male germ cells fr
194 We discuss the placental secretome including glycoproteins, microRNAs and extracellular vesicles as p
195 find that rather than the mass or length of glycoprotein modifications, the stability of DC-SIGN is
196 , disease course, and myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between childr
197 pid protein (PLP) and myelin oligodendrocyte glycoprotein (MOG), the membrane proteins found in the m
198 le-Ab-seronegative, 4 myelin oligodendrocyte glycoprotein (MOG)-Ab-seropositive and 4 AQP4-Ab-seroneg
199 gG antibodies against myelin-oligodendrocyte glycoprotein (MOG-IgG) have been increasingly recognised
200 is a posttranslational modification on a few glycoproteins, most commonly in the brain, on the neural
202 rs mastigonemes, filamentous polymers of the glycoprotein MST1, to the extracellular surface of Chlam
203 a gel-like material comprised mainly of the glycoprotein mucin and water and it displays both hydrop
204 one of the unique metacyclic variant surface glycoprotein (mVSG) coat protein transcripts identified.
205 Here we present the crystal structure of glycoprotein N (G(N)) from the tomato spotted wilt virus
206 ere correlated with inflammation-attenuating glycoprotein non-metastatic melanoma protein B (GPNMB) s
208 olated from papaya, we identified a secreted glycoprotein of 15 kDa, designated as Ppal15kDa, using l
212 T cells that are reactive against the spike glycoprotein of SARS-CoV-2 in the peripheral blood of pa
213 eral monoclonal antibodies that target the S glycoprotein of SARS-CoV-2, which we identified from mem
217 otein, which show a higher homology to spike glycoproteins of human endemic coronaviruses, compared w
218 d the profile of N-glycans from the salivary glycoproteins of Lutzomyia longipalpis, vector of viscer
220 y to SARS-CoV, SARS-CoV-2 utilises the Spike glycoprotein on the envelope to recognise and bind the h
221 eration of a library of Cys mutations in Env glycoprotein on the viral surface, covalent labeling of
224 treatment by efflux transporters, such as P-glycoprotein (P-gp) at the blood-brain barrier (BBB).
226 ug resistance, the drug efflux behavior of P-glycoprotein (P-gp) remains a prominent challenge in can
229 s of individual proteins in the collagen and glycoprotein phases of connective tissue extracellular m
230 tigate proteome dynamics in the collagen and glycoprotein phases of connective tissues by exploiting
232 dy, we used DNA vaccination against the MACV glycoprotein precursor complex (GPC) and murine hybridom
233 ty in human cells, providing evidence that a glycoprotein precursor variant, present in ticks, has se
234 ms representing those present in the nascent glycoproteins (prior to enzymatic modifications in the G
236 initiate infection, the SARS-CoV-2 spike (S) glycoprotein promotes attachment to the host cell surfac
238 NA vaccine encoding the soluble Hendra virus glycoprotein protected up to 70% of Syrian hamsters from
240 as9 gene editing identified the inflammatory glycoprotein PTX3 enriched in DXR-elicited sEV as a crit
242 ick-specific amino acid variant in the viral glycoprotein region that dramatically reduces its fusion
244 Integrin alpha V (ITGAV), a transmembrane glycoprotein responsible for cell-to-matrix binding has
245 cence reveals that coexpression of all three glycoproteins results in their localization to a juxtanu
246 r (AMT)/methylammonium permease (MEP)/Rhesus glycoprotein (Rh) family of ammonia (NH(3)/NH(4) (+)) tr
247 d overall faster protein turnover within the glycoprotein-rich interfascicular matrix compared to the
248 blast fungus Magnaporthe oryzae(1), powerful glycoprotein-rich mucilage adhesives(2) cement melanized
250 glycoprotein M) and a specific truncation of glycoprotein RL13, these did not explain the DIDS resist
252 ding free energy changes of SARS-CoV-2 spike glycoprotein (S protein) and host angiotensin-converting
256 complete extramembrane portion of the viral glycoprotein shell and allowed a detailed description of
257 he EBOV glycoprotein substituted for the VSV glycoprotein show greater safety and efficacy in targeti
260 c vesicular stomatitis viruses with the EBOV glycoprotein substituted for the VSV glycoprotein show g
261 rehensive characterization of some important glycoproteins, such as tumor biomarkers and recombinant
262 tions in hemagglutinin-esterase fusion (HEF) glycoproteins suggests that antigenic drift may also hav
263 e when the MLD was expressed within the EBOV glycoprotein than when EBOV lacked the mucin-like domain
264 id protein and distinct inserts in the spike glycoprotein that appear to be associated with high case
265 Lastly, we have identified peptides in the S glycoprotein that are likely to be presented in human le
266 (NS1) is a membrane-associated and secreted glycoprotein that functions in flavivirus replication an
267 l fluid (CSF) lipocalin 2 (LCN2), a secreted glycoprotein that has been suggested as mediating neuron
268 fold with distant homology to another CCHFV glycoprotein that is suggestive of a gene duplication ev
270 an be obscured by the glycosaminoglycans and glycoproteins that coat pathogenic as well as malignant
272 ntly, these two features of the SARS-CoV-2 S glycoprotein, the furin cleavage site and D614G, have ev
273 9) pandemic, are focused on SARS-CoV-2 spike glycoprotein, the primary target for neutralizing antibo
274 en activator receptor (suPAR) is a signaling glycoprotein thought to be involved in the pathogenesis
275 ptor binding domain (RBD) of the viral spike glycoprotein tightly (K(D) of 2 nM), and a 2.6- angstrom
277 tor-binding domain within its trimeric spike glycoprotein to human angiotensin-converting enzyme 2.
278 within the Golgi, where it allows ER-escaped glycoproteins to bypass the classical N-glycosylation tr
279 ants and with existing 3D structures of both glycoproteins to generate molecular dynamics simulations
280 xed out of normal proximal tubules through P-glycoprotein transporter while being retained in cancero
281 tivation and regulation of NK cells by Ebola glycoprotein.TRIAL REGISTRATIONClinicalTrials.gov NCT023
282 The respiratory syncytial virus fusion (F) glycoprotein trimer-stabilized in the prefusion conforma
284 est that Platynereis CRZ1/GnRHL1 coordinates glycoprotein turnover and energy homeostasis with growth
287 ve emerged to suggest that modulation of the glycoprotein VI (GPVI) platelet receptor could be harnes
288 vation of influenza virus hemagglutinin (HA) glycoprotein via cleavage by host cell proteases is esse
289 ll-mediated immune response specific for the glycoproteins was also detected in most of the vaccinate
290 ibutes to the activation of the SARS-CoV-2 S glycoprotein, we evaluated the ability of protease inhib
291 cts interactions with sialylated glycans and glycoproteins, we determined high-resolution crystal str
294 f the humoral immune response, the spike (S) glycoprotein, which mediates cell entry and membrane fus
295 metry proteomics and identified multiple ECM glycoproteins whose expression and function in IgAN is u
296 ogenic targets against the coronavirus spike glycoprotein will provide crucial advances towards the d
298 own by the aliases GP340 and SALSA), a large glycoprotein with multiple O-glycosylation repeats.
300 ding the binding mechanism of specific virus glycoproteins with cellular receptors, can be useful for