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1 ransfer bound phosphates between cytosol and glycosome.
2  essential bound-phosphate moiety within the glycosome.
3 y and localized the endogenous enzyme to the glycosome.
4 s and that it is sequestered in the parasite glycosome.
5 que metabolic organelle in the parasite: the glycosome.
6 s in a unique single-membrane organelle, the glycosome.
7  strong driving force for maintenance of the glycosome.
8 athway of these organisms resides within the glycosome.
9 nals (PTS2s) to direct their import into the glycosome.
10 novani HGPRT is localized exclusively to the glycosome.
11  of HGPRT, all of which was localized to the glycosome.
12  suggesting a heretofore unknown role of the glycosome.
13 ntial for protein import into the parasites' glycosomes.
14 ytic direction with production of ATP in the glycosomes.
15 intermediary metabolism and hence are called glycosomes.
16 roxide dismutases (SODs) in mitochondria and glycosomes.
17 ile TbPAGM localized to both the cytosol and glycosomes.
18 mes within peroxisome-like organelles called glycosomes.
19 dosomal system and was additionally found on glycosomes.
20 and the peroxisomes-related organelles named glycosomes.
21  steps inside specialized peroxisomes, named glycosomes.
22 e topogenic signal targeting proteins to the glycosome, a fuel-metabolizing microbody unique to these
23 that could act as a targeting signal for the glycosome, a kinetoplastid-specific organelle.
24                                              Glycosomes also play a pivotal role in life-cycle regula
25 g signal (PTS-1) that steers proteins to the glycosome, an organelle unique to Leishmania and related
26 PPP is localized to both the cytosol and the glycosome and adding it to the glycolytic model without
27 eroxins are proteins involved in peroxisome, glycosome and glyoxysome biogenesis.
28  is compartmentalized exclusively within the glycosome and that the COOH-terminal tripeptide of the p
29 strated that TcGPXI is localized to both the glycosome and the cytosol.
30 ermine the complement of proteins within the glycosome and the function of compartmentation.
31 ut the cell in numerous puncta distinct from glycosomes and other organelles.
32 ng proteins to these organelles suggest that glycosomes and peroxisomes may have evolved from a commo
33 trong support for the common origin model of glycosomes and peroxisomes.
34 usively found in the flagellum, TbAK2 in the glycosome, and TbAK3 in the cytosol of T. brucei.
35 lized within vesicular structures, including glycosomes, and can be visualized after 30-60 min.
36 ivities but lacked markers for mitochondria, glycosomes, and lysosomes.
37 ch as the acidocalcisome, hydrogenosome, and glycosome; and e) the highly polarized endocytic pathway
38                    Thus, unlike peroxisomes, glycosomes are essential organelles.
39                                              Glycosomes are membrane-bounded microbody organelles tha
40                                              Glycosomes are peroxisome-like organelles essential for
41 r mode of action, including activity against glycosome-associated proteins.
42 trypanosomatids, and would therefore disrupt glycosome biogenesis and prevent parasite growth.
43                                              Glycosome biogenesis in trypanosomatids occurs via a pro
44                                              Glycosome biogenesis is mediated by proteins called "per
45 man host, and the vital importance of proper glycosome biogenesis to the parasite, render these perox
46  glycosyl phosphatidylinositol biosynthesis, glycosome biogenesis, and polyamine biosynthesis.
47                           The mutant retains glycosomes but mislocalizes a subset glycosomal proteins
48 arasite; and (iv) that ARG is present in the glycosome, but this subcellular milieu is not essential
49           The epimerase was localized to the glycosomes by immunofluorescence microscopy and subcellu
50 ycolytic steps need to be regenerated in the glycosomes by kinases, such as phosphoenolpyruvate carbo
51 n of protein import into this organelle, the glycosome, can be accomplished through RNA interference
52  lacked markers for mitochondria, lysosomes, glycosomes, cytosol, and plasma membrane.
53  for the exchange of metabolites between the glycosomes, cytosol, mitochondrion and the host medium.
54               Although the metabolic role of glycosomes differs substantially from that of the peroxi
55 ve shown that in the absence of glucose, the glycosome exhibits mild acidification from pH 7.4 +/- 0.
56 ssed in peroxisome-related organelles, named glycosomes, expression of FRDm2 has not been detected to
57 isolate the first Leishmania mutant (gim1-1 [glycosome import] mutant) with a defect in the import of
58 C)}GGAKL) for investigating pH regulation of glycosomes in live procyclic form Trypanosoma brucei Whe
59 are able to observe the pH conditions inside glycosomes in response to starvation conditions.
60 inant proteins localized endogenous TbPMM to glycosomes in the bloodstream form of the parasite, whil
61 l diseases, contain unique organelles called glycosomes in which the first seven glycolytic enzymes a
62 stronic transcription, trans-splicing, and a glycosome-like organelle.
63  disease, compartmentalize glycolysis within glycosomes, metabolic organelles related to peroxisomes.
64 n evolutionary divergence in the function of glycosomes (modified peroxisomes) in diplonemids versus
65 the most divergent peroxisomes known are the glycosomes of trypanosomes and their relatives.
66 etabolically specialized peroxisomes include glycosomes of trypanosomes, which have come to compartme
67 luding additional enzymatic reactions in the glycosome, or (ii) adding a mechanism to transfer bound
68 ays in unique subcellular microbodies called glycosomes, organelles related to the peroxisomes of mam
69          Interestingly, TbPIP39 localizes in glycosomes, peroxisome-like organelles that compartmenta
70 ting motif caused GPI-PLCp to associate with glycosomes (peroxisomes).
71  L. major; (ii) sequestration of GPI-PLCp to glycosomes protects free protein-GPIs from cleavage by t
72                      Thus, interference with glycosome protein import makes glucose toxic to trypanos
73 Taken together, these data indicate that the glycosome provides significant, but not complete, protec
74 osomes) has been proposed to facilitate this glycosome remodeling.
75               Here, we report that, although glycosome-resident enzyme T. brucei hexokinase 1 (TbHK1)
76  3-phosphate, which is produced in vivo by a glycosome-resident glycerol kinase, mitigated acid inact
77  These observations support a model in which glycosome sequestration of a catabolic GPI-PLCp preserve
78 of gim1-1 and distinctive role of Leishmania glycosomes suggest that future studies of this system wi
79      This protein has a unique non-canonical glycosome targeting signal responsible for its dual loca
80 HK1, particularly given the acidification of glycosomes that can be induced under a variety of parasi
81                                              Glycosome turnover occurs by autophagic degradation of r
82 ll as gain insights into the function of the glycosome, we used a positive genetic selection procedur
83                                              Glycosomes were also observed to be more resistant to ex
84 o enrichment in the acidocalcisome fraction; glycosomes were concentrated 5-fold.
85 bsequently demonstrated to be present in the glycosome, whereas the polyamine biosynthetic enzymes, i
86 icroscopy also revealed increased numbers of glycosomes, while immunofluorescence microscopy showed i
87                         Pexophagy (fusion of glycosomes with acidic lysosomes) has been proposed to f