ライフサイエンスコーパス: grand

1 y in regular (11 year) and recently reported grand (350-400 year) solar cycles caused by actions of t

2 a single Cd(II) binding site, GrandL12AL16C [Grand = AcG-(LKALEEK)(5)-GNH(2)], GrandL26AL30C, and Gra

3 , discrimination, shocking perseverance, and grand adventure.

4 sponsible for Mendelian disorders provides a grand and unprecedented opportunity for geneticists.

5 e classified into a Murre virus species; and Grand Arbaud virus, Precarious Point virus, and Manawa v

6 d to cover a wide range of hydrophobicities (grand average hydropathy (GRAVY) scores of -0.6 to 1.9).

7 The grand average of all the significantly correlated subtha

8 amino acid structures, isoelectric point and grand average of hydropathy (GRAVY) values of the 7 most

9 The grand-averaged difference in root mean squared voltage b

10 ca and the Bahamas (Abaco, Eleuthera, Exuma, Grand Bahama, Long Island and New Providence).

11 anging from 79.1% to 100% in Long Island and Grand Bahama, respectively, illustrating the capacity of

12 ranged from 0.989 in Long Island to 1.000 in Grand Bahama, with limited haplotype sharing observed am

13 Specifically, in the Labrador Sea/Grand Banks for populations from NA, 26% and 24% of vari

14 A case study was conducted on the Grand Banks of Newfoundland, Canada.

15 Mg-metal batteries is investigated through a grand canonical density functional theory (DFT) approach

16 The grand canonical ensemble lies at the core of quantum and

17 d at an atomistic resolution within the semi-grand canonical ensemble using mutation moves to rapidly

18 iversal features of disordered bosons in the grand canonical ensemble.

19 nt to that of a lattice gas of bosons in the grand canonical ensemble; bromine doping introduces diso

20 ed physiological concentration, although the grand canonical free energy profiles are uphill for HTT

21 et was allowed to fluctuate via the use of a Grand Canonical Monte Carlo (GCMC) methodology.

22 Grand canonical Monte Carlo (GCMC) simulation provides m

23 d vapor adsorption experiments together with Grand Canonical Monte Carlo (GCMC) simulations, and coul

24 uantum mechanics (QM)-based force fields and grand canonical Monte Carlo (GCMC) simulations.

25 ntal observations are consistent with ReaxFF grand canonical Monte Carlo (ReaxFF-GCMC) calculations,

26 equate sampling of Mg(2+) ion binding with a grand canonical Monte Carlo MD method.

27 Enabled by a new grand canonical Monte Carlo method for membrane simulati

28 Grand canonical Monte Carlo simulation reveals that not

29 of 26.7 kJ/mol, which was validated through grand canonical Monte Carlo simulation studies of CH4 ad

30 tical and methodological developments to the grand canonical Monte Carlo simulation technique.

31 Grand canonical Monte Carlo simulations agree that ultra

32 Grand canonical Monte Carlo simulations and single compo

33 CO(2)/H(2)O gas mixtures were determined by grand canonical Monte Carlo simulations at temperature/p

34 hotoelectron spectroscopy, and complementary grand canonical Monte Carlo simulations coupled to a tig

35 Extensive grand canonical Monte Carlo simulations in combination w

36 Grand canonical Monte Carlo simulations of defective can

37 The study starts with grand canonical Monte Carlo simulations on a suite of 10

38 e filling of one site compared to the other: grand canonical Monte Carlo simulations support these ex

39 f Cs migration in partially saturated clays, Grand Canonical Monte Carlo simulations were applied to

40 Grand canonical Monte Carlo simulations were carried out

41 n these structures was studied by performing grand canonical Monte Carlo simulations with appropriate

42 diffraction, density functional theory, and grand canonical Monte Carlo simulations, we show that in

43 area was estimated to be 422 m(2) g(-1) from grand canonical Monte Carlo simulations.

44 terpenetrated structure has been modelled by grand canonical Monte Carlo simulations.

45 combined with oscillating chemical potential Grand Canonical Monte Carlo/molecular dynamics simulatio

46 dynamics and oscillating chemical potential grand canonical Monte Carlo/molecular dynamics to invest

47 Here, we apply the recently developed grand canonical potential kinetics (GCP-K) formulation o

48 In this article we make use of a grand canonical screening approach recently proposed to

49 tion of surface spectroscopic techniques and grand-canonical electronic-structure calculations in ord

50 Using grand-canonical electronic-structure calculations, we di

51 osition pathways of LiBH4 nanoclusters using grand-canonical free-energy minimization based on total

52 nic structure methods and characterized with Grand-canonical Monte Carlo simulations for methane upta

53 and U measured in periphyton from springs in Grand Canyon (United States) and were compared to U conc

54 w paleocanyon that was carved in the eastern Grand Canyon 25 to 15 million years ago (Ma), negating t

55 consistent with a 5 to 6 Ma age for western Grand Canyon and Marble Canyon.

56 (4)He/(3)He spectra for eastern Grand Canyon apatites of differing He date, radiation da

57 Projected temperature for the Grand Canyon area, however, is expected to rise by as mu

58 (4)He/(3)He thermochronometry data from the Grand Canyon basement that tightly constrain the near-su

59 that geological observations do not require Grand Canyon carving coeval with Colorado River integrat

60 Flowers and Farley propose that the Grand Canyon is 70 million years old.

61 The Grand Canyon is one of the most dramatic features on Ear

62 Similar data for the western Grand Canyon provide evidence that it was excavated to w

63 Groundwater is a critical resource in the Grand Canyon region, supplying nearly all water needs fo

64 d precipitation and temperature data for the Grand Canyon region.

65 nterior-basin deposits near the mouth of the Grand Canyon show that no paleocanyon existed in that ar

66 at hundreds of spring locations in and near Grand Canyon supports important ecosystems in this mostl

67 hronometry to propose that the western paleo-Grand Canyon was nearly as deep 70 million years ago (Ma

68 ions from Arizona and Utah, separated by the Grand Canyon, to dissect genetic variation controlling V

69 tarkly contrasting models for the age of the Grand Canyon-70 versus 6 million years-can be reconciled

70 s that H3K27me3-marked large DNA methylation grand canyons represent a set of very-long-range loops a

71 ge (>7.3 kb) DNA methylation nadirs (termed "grand canyons") can form long loops connecting anchor lo

72 rovisioned at Stingray City Sandbar (SCS) in Grand Cayman have altered diel activity patterns and dec

73 by CENTER CITY (CCT; Arabidopsis MED12) and GRAND CENTRAL (GCT; Arabidopsis MED13) are required for

74 single- or few-layered nanosheets remains a grand challenge and becomes the bottleneck to essential

75 he ecosystem services they provide present a grand challenge and major opportunity as we direct our r

76 rically functionalized polyoxometalates is a grand challenge as it could lead to new molecular nanoma

77 The grand challenge before us is to sustainably meet humanit

78 eously produce viable tools for a biological grand challenge domain with no extant solutions.

79 sic microbiology and medicine, but remains a grand challenge due to the fact that many species adopt

80 hanging climate and dwindling resources is a grand challenge facing mankind.

81 tanding of human intelligence is perhaps the grand challenge for 21st-century science, with broad imp

82 synthesizability of inorganic materials is a grand challenge for accelerating their discovery using c

83 knowledge across the Tree of Life remains a grand challenge for biodiversity science.

84 eural circuits through network training is a grand challenge for biomedicine and engineering applicat

85 neered and industrial environments remains a grand challenge for geomicrobiology.

86 Rebuilding marine life represents a doable Grand Challenge for humanity, an ethical obligation and

87 cules that target allosteric sites remains a grand challenge for ligand discovery.

88 the neural correlates of consciousness is a grand challenge for neuroscience.

89 rochemical window in solid electrolytes is a grand challenge for the synthesis of battery materials.

90 ing the combination of these properties is a grand challenge for the synthesis of sulfide-based solid

91 This grand challenge has mostly proved ineffective because of

92 er in response to environmental stimuli is a grand challenge in active materials, structures, and rob

93 reserving 3D context, represents an enduring grand challenge in biology.

94 enome of an organism into its phenotype is a grand challenge in biology.

95 proteins from first principles represents a grand challenge in chemistry and structural biology.

96 pologies at the molecular level represents a grand challenge in chemistry.

97 tatistics in complex nonlinear systems are a grand challenge in climate, material, and neuroscience a

98 -correlation functionals has long remained a grand challenge in density functional theory (DFT), as i

99 dioxide to multicarbon products remains as a grand challenge in electrochemical CO2 reduction.

100 A grand challenge in material science is to understand the

101 anostructures and identical composition is a grand challenge in materials chemistry.

102 A grand challenge in materials research is to understand c

103 has been developed to address the number one grand challenge in metabolomics, which is the large-scal

104 specific functions, diseases and traits is a grand challenge in modern genetics.

105 stable multidimensional solitary waves is a grand challenge in modern science.

106 s of metastable inorganic solids, which is a grand challenge in solid-state chemistry, requires the d

107 tionship to solid-state phase formation is a grand challenge in synthesis science.

108 n from large-scale functional data sets is a grand challenge in systems biology.

109 The grand challenge in the development of atomically dispers

110 It remains a grand challenge in the field of chemistry to synthesize

111 A grand challenge is to develop a general cancer screening

112 Modern chemistry's grand challenge is to significantly improve catalysts fo

113 It is currently a grand challenge of chemistry, materials science, and eng

114 In silico catalyst design is a grand challenge of chemistry.

115 ell as climate atmosphere ocean science is a grand challenge of contemporary science with important s

116 us providing instrumental technology for the grand challenge of engineering N2-fixing cereals.

117 n as a complementary solution to address the Grand Challenge of global food security and environmenta

118 oxo clusters and related materials remains a grand challenge of inorganic chemistry.

119 Cities will play a key role in the grand challenge of nourishing a growing global populatio

120 stly arising from feed production, is thus a grand challenge of sustainability science.

121 A grand challenge of systems biology is to predict the kin

122 liquids, and offering the potential to solve grand challenge problems.

123 A grand challenge that crosses synthetic chemistry and bio

124 veloped a new microgel array to address this grand challenge through robotic printing of complex stem

125 It is a grand challenge to develop a truly effective medication

126 izer use and loss to the environment poses a grand challenge to farmers and society, and necessitates

127 However, it has been a grand challenge to maintain the viability, functionality

128 It remains a grand challenge to replace platinum group metal (PGM) ca

129 A grand challenge to solve a large-scale linear inverse pr

130 mising their crystalline superiority holds a grand challenge to unveil their pristine electrocatalyti

131 Desikan-Killiany-Tourville, and MICCAI 2012 Grand Challenge).

132 Control of these complex systems is a grand challenge, for example, in mitigating the effects

133 Princeton University Health Grand Challenge, US National Institutes of Health (NIH),

134 efficient Z-scheme photocatalysts remains a grand challenge.

135 films at submicrometer resolution presents a grand challenge.

136 t unite all lineages (the tree of life) is a grand challenge.

137 edict such representative features remains a grand challenge.

138 round of the D3R (Drug Design Data Resource) Grand Challenge.

139 and their ecological determinants remains a grand challenge.

140 ever, in silico vaccine prediction remains a grand challenge.

141 trocatalysts at the atomic level, which is a grand challenge.

142 choose, an aspiration of the Dial-a-Molecule Grand Challenge.

143 roton-exchange-membrane fuel cells remains a grand challenge.

144 and fabricate biological machines remains a grand challenge.

145 Protein structure prediction is a grand challenge.

146 uld accelerate progress toward meeting this "grand challenge."

147 rrelated quantum matter with applications in grand-challenge problems.

148 Special attention will be paid to the grand-challenge related to detection, quantification and

149 which can offer some solutions to society's grand challenges associated with sustainability and ener

150 Grand Challenges Canada (Government of Canada), Saving B

151 Grand Challenges Canada (Saving Brains).

152 Bill & Melinda Gates Foundation, Grand Challenges Canada, and the UK Medical Research Cou

153 Grand Challenges Canada, Bill & Melinda Gates Foundation

154 Grand Challenges Canada, Bill & Melinda Gates Foundation

155 Grand Challenges Canada, the Bill & Melinda Gates Founda

156 Bill & Melinda Gates Foundation, Grand Challenges Canada, UK Medical Research Council.

157 National Institutes of Health, Grand Challenges Canada.

158 MQ Transforming Mental Health and Grand Challenges Canada.

159 Canadian Institutes of Health Research; Grand Challenges Canada; Ontario SPOR Support Unit and t

160 ment to define this conversion as one of the Grand Challenges for Biology in the 21st Century.

161 eading their functional implications present grand challenges for plant biology.

162 anel of leading experts, reflecting a set of grand challenges for spatial lifecourse epidemiology in

163 om microbial single cells is one of the last grand challenges in (bio)analytical chemistry.

164 One of the grand challenges in chemistry has been to directly obser

165 Gene expression prediction is one of the grand challenges in computational biology.

166 One of the grand challenges in contemporary chemical biology is the

167 One of the grand challenges in contemporary systems chemistry resea

168 Grand challenges in global change research and environme

169 Health (as part of the Bill & Melinda Gates Grand Challenges in Global Health Initiative).

170 reservoir of enzymes that could help address grand challenges in human health, energy, and sustainabi

171 mbination of enabling features to tackle the grand challenges in pressure- and tactile-sensing applic

172 tocatalyts for water splitting is one of the grand challenges in solar energy conversion.

173 gene expression profiles has been one of the grand challenges in systems biology.

174 this field of research and its relevance to grand challenges in the treatment of neurological disord

175 One of the grand challenges of biophysical chemistry is to understa

176 g major needs of the society, especially the grand challenges of energy, health, and environment.

177 The four grand challenges of imaging research-increasing evidence

178 nt-efficient crops are a solution to the two grand challenges of modern agriculture: improving food s

179 mate molecular building blocks is one of the grand challenges of our time.

180 cular profile datasets represents one of the grand challenges of Systems Biology.

181 yploidy toward confronting interdisciplinary grand challenges of the 21(st) century.

182 US National Institutes of Health, Princeton Grand Challenges Program.

183 Future directions and grand challenges to realize these goals are highlighted

184 ine three interdependent, cross-disciplinary grand challenges underpinning this research endeavor.

185 We then examine several environmental "grand challenges" and discuss how urban land teleconnect

186 r conclusions, we present our choice of the "grand challenges" for the preservation and sharing of ch

187 One of the remaining "grand challenges" in chemistry is the development of a n

188 verse group of international experts on the 'grand challenges' in small-molecule drug discovery with

189 Related grand challenges, including shape sensing, finding, and

190 insufficient selectivity and activity remain grand challenges.

191 Human Development and Saving Lives at Birth Grand Challenges.

192 e social dynamics prevent the formation of a grand coalition and therefore full cooperation.

193 ch's Storm-petrel (Hydrobates leucorhous) on Grand Colombier Island in the St.

194 As part of the "Grand Convergence: Aligning Technologies and Realities i

195 One of the grand current research challenges is to improve the ener

196 r minimum) occurred before the current super-grand cycle start.

197 These grand cycle variations are probed by alpha - Omega dynam

198 with a period of 1950 +/- 95 years (a super-grand cycle) are discovered by applying a running averag

199 leads to beating effects responsible for the grand cycles (350-400 years) superimposed on a standard

200 kward for 800 years reveals the two 350-year grand cycles superimposed on 22 year-cycles with the fea

201 r the next millennium predicts further three grand cycles with the closest grand minimum occurring in

202 aternal grandmother smoking in pregnancy and grand daughters having adverse scores in Social Communic

203 affect fertility of resulting daughters and grand-daughters.

204 up in longevity gains, and avoid a so-called grand divergence in health and longevity.

205 When construction of the Grand Ethiopian Renaissance Dam (GERD) is completed, the

206 Unraveling the grand evolution from nonscalable to scalable optical pro

207 Here, we investigate the grand evolution of the optical properties by comparing t

208 Islands provide the venue of one of nature's grand experiments in evolution.

209 Cassini's Grand Finale orbits provided for the first time in-situ

210 dering at the mesoscopic scale are among the grand fundamental science challenges.

211 he dissolved phases, were collected from the Grand, Kalamazoo, Saint Joseph, and Lower Fox rivers and

212 les from five Lake Michigan tributaries [the Grand, Kalamazoo, St. Joseph, and Lower Fox Rivers, and

213 tic Canada's largest freshwater wetland, the Grand Lake Meadows (GLM) and the associated Saint John/W

214 Epilepsy with grand mal on awakening (EGMA) is a well-defined subtype

215 N2O, and NH3 from a 2006 model year Mercury Grand Marquis flexible fuel vehicle (FFV) operating on E

216 Exposure to low-protein grand-maternal diet leads to decreased ovarian reserve a

217 We used self-reported grand-maternal gestational weight gain, diet, physical a

218 The inverse associations between grand-maternal lifestyle and BMI in grandchildren were m

219 The inverse associations of grand-maternal lifestyle with BMI of offspring were not

220 e with BMI of offspring were not modified by grand-maternal pre-pregnancy BMI, grandchild age, or gra

221 ification is successful in increasing yield (grand mean + 20.3%), but it also results in a loss of sp

222 CP without protein or leucine ingestion, the grand mean +/- SEM plasma 3-HIB concentration decreased

223 We calculated a grand mean for individual seafood items, based on report

224 Farmed fish generally had lower grand mean Hg concentrations than their wild counterpart

225 sirable direction for 98% of variables and a grand mean of [Formula: see text] (SD = 0.13), indicativ

226 /MU was stable but with yield lower than the grand mean.

227 performance (0.21 fewer cognitive errors at grand-mean-centered age 70 years) than those with low ac

228 rom 35 +/- 2 to 14 +/- 1 micromol/L) and the grand median [quartiles] FGF21 concentration increased (

229 ting total solar irradiance estimates during grand minima.

230 further three grand cycles with the closest grand minimum occurring in the forthcoming cycles 26-27

231 e next three decades (2019-2055) to a Modern grand minimum similar to Maunder one.

232 The most recent "grand minimum" of solar activity, the Maunder minimum (M

233 in the cerebral cortex, cerebellum, parotid grand, myocardium, and bowel mostly reflected the (18)F-

234 two dessert bananas of commercial interest (Grand Nain and Gros Michel), alongside a newly created h

235 Cavendish', 'Giant Cavendish', 'Dwarf Red', 'Grand Nain', 'Eilon', 'Gruesa', 'Silver', 'Ricasa', 'Wil

236 "This grand natural scene was a physical correlate of Francis'

237 witchable fluorescent proteins (PS-FPs) open grand new opportunities in biological imaging.

238 males switching to invest in their existing (grand)offspring, thereby increasing their inclusive fitn

239 metabolic dysfunctions in the offspring and grand-offspring of injected males and affects the sperm

240 nd-offspring, and F3 transgenerational great-grand-offspring were observed.

241 ncreases in pathologies in the F2 generation grand-offspring, and F3 transgenerational great-grand-of

242 cts from the National Heart, Lung, and Blood Grand Opportunity Exome Sequencing Project.

243 ed by the 1000 Genomes Project and the NHLBI Grand Opportunity Exome Sequencing Project.

244 rameters on million-year time scales induce "grand orbital cycles," but the behavior and the paleoenv

245 Immunomedics, Amgen, Canceropole Grand Ouest, the GOELAMS/LYSA group and the French Natio

246 ansfer of information, such as the effect of grand parental smoking or exposure to other toxic compou

247 rate and interactive effects of parental and grand-parental ages at breeding on descendants' mortalit

248 e breeding age effects were not modulated by grand-parental larval diet quality or competitive enviro

249 esigned three-stranded coiled coils (TRI and Grand peptides formed using a heptad repeat approach), w

250 to convey a sense that one need not have a "grand plan" to have a successful life in science.

251 f tissue engineering has not full-filled its grand potential of engineering such combinatorial scaffo

252 m 36 patients spanning nine counties and the Grand Princess cruise ship.

253 Cultivars Iceberg and Grand Rapids that were released in the 18th and 19th cen

254 regulate seed germination in photosensitive 'Grand Rapids' lettuce (Lactuca sativa), we investigated

255 stance at this locus originate from cultivar Grand Rapids.

256 nd cultures such as Greater Nicoya and Casas Grandes represent Mesoamerican outposts in the Isthmo-Co

257 rement of single cell secretions have become grand research barriers.

258 loyed in wastewater-dominated reaches of the Grand River (Kitchener, ON) to verify their feasibility

259 h across an urban environment in the central Grand River watershed (Ontario, Canada).

260 ature, land use and surficial geology in the Grand River, Canada, a seventh-order river in an agricul

261 have been reported for several years in the Grand River, in southern Ontario, Canada, in close proxi

262 uscaloosa, Weyburn-Midale, Bass Islands, and Grand Ronde carbon sequestration geologic formations.

263 In this Grand Round we describe a 2-year-old child from the USA

264 In this Grand Round we review the clinical features, epidemiolog

265 In this Grand Round, we present a dramatic case of cutaneous spo

266 In this Grand Round, we present the case of a previously healthy

267 In this Grand Round, we present the case of an otherwise healthy

268 In this Grand Round, we report a case of a 20-year-old active du

269 In this Grand Round, we report eight HIV-negative refugees, who

270 In this Grand Round, we review the clinical features of hypervir

271 In this Grand Round, we review the clinical features, epidemiolo

272 In this Grand Round, we review the clinical features, epidemiolo

273 ere presented during a virtual ophthalmology grand rounds and discussed with the director of clinical

274 This Grand Rounds review describes the evaluation and evidenc

275 The Oncology Grand Rounds series is designed to place original report

276 The Oncology Grand Rounds series is designed to place original report

277 This Grand Rounds summarizes the factors to consider when cou

278 In this Grand Rounds, 2 prominent clinicians debate whether to i

279 In this Grand Rounds, 2 prominent endocrinologists debate the is

280 In this Grand Rounds, the guideline is reviewed and an expert di

281 In this grand rounds, we focus on development, validation, and a

282 In this Neurology Grand Rounds, we use transcranial magnetic stimulation a

283 Residents of Bocozel or Grand Saline who were eligible for the vaccination campa

284 +/- 0.51 D vs 2.03 +/- 1.03 D, P < .001) and Grand Seiko (0.46 +/- 0.45 D vs 0.99 +/- 1.0 D, P < .001

285 ta Rica (n = 9; A.D. 800-1250) and the Casas Grandes sites of Paquime and Convento in northwest Mexic

286 e oscillations is found to coincide with the grand solar minimum (the Maunder minimum) occurred befor

287 Grand stability challenges exist when PGM catalyst loadi

288 ations in the hypothalamus-pituitary-adrenal grand stress.

289 ortality displacement, which is the ratio of grand sum deficit to grand sum excess mortality, decreas

290 , which is the ratio of grand sum deficit to grand sum excess mortality, decreased as a function of e

291 Ultimately, this grand synthesis should improve predictive capability of

292 s within both the classical scenario and the Grand Tack scenario of terrestrial planet formation, and

293 tive method, the best estimate of the global grand total is roughly 200 extinctions.

294 ome at physiological pH, this resulting in a grand total of 1151 gene products identified after the c

295 A grand unified model (GUM) is developed to achieve fundam

296 onopoles resulting from symmetry breaking in grand unified theories.

297 Clark argues that predictive coding offers a Grand Unified Theory (GUT) of brain function.

298 oach to evolutionary biology, in lieu of any grand unified theory updated to include microbial genomi

299 cal control agents, these results expand the grand view of the diversity of mycoviruses and provide p

300 ient inhabitants of Greater Nicoya and Casas Grandes with contemporary Isthmo-Columbian and Greater S