ライフサイエンスコーパス: granulosa

1 rived neurotrophic factor (BDNF) secreted by granulosa and cumulus cells as an ovarian factor stimula

2 current study labeled AVT and MST mRNA in T. granulosa and the red-legged salamander (Plethodon sherm

3 ative cell-cell interactions between ovarian granulosa and theca cells as an approach to cHRT.

4 Supporting cells (Sertoli and granulosa) and steroidogenic cells (Leydig and theca-int

5 In male roughskin newts (Taricha granulosa), AVT is an important facilitator of several r

6 In T. granulosa, AVT ISH-labeled cells were found to be widesp

7 ctures containing disorganized, pleiomorphic granulosa by 6 weeks of age.

8 Taricha granulosa can exhibit high TTX levels, presumably concen

9 Primordial follicles, consisting of granulosa cell (GC)-enveloped oocytes are maintained in

10 While granulosa cell ablation of individual Smad2 or Smad3 cau

11 In mouse granulosa cell and cumulus cell expansion assays, mouse

12 ivator genes, and impaired the expression of granulosa cell and oocyte-specific genes.

13 ous, endometrioid, mucinous, clear cell, and granulosa cell carcinomas and in precursor lesions such

14 e that the TAF4b protein is expressed in the granulosa cell compartment of the mammalian ovarian foll

15 s in two different in vitro models of oocyte-granulosa cell complexes.

16 otes PF formation by facilitating oocyte and granulosa cell development.

17 antral stage, multiple genes associated with granulosa cell differentiation and oocyte maturation wer

18 vation of KRAS in granulosa cells blocks the granulosa cell differentiation pathway, leading to the p

19 ress Cre prior to or after the initiation of granulosa cell differentiation, respectively.

20 ed a conditional mutant mouse model in which granulosa cell expression of Runx2 and Cbfb was deleted

21 otes canonical WNT signaling but also alters granulosa cell fate decisions by maintaining epithelial-

22 Lats1 and Lats2 are required for ovarian granulosa cell fate maintenance.

23 te the effects of BMPR-IB gene modulation on granulosa cell function in goats.

24 d cell viability were studied to explore the granulosa cell function on BMPR-IB gene modulation.

25 ent of subfertility associated with abnormal granulosa cell function.

26 a suggest that TAF4b integrates a program of granulosa cell gene expression required for normal ovari

27 l role for Lats1/2 in the maintenance of the granulosa cell genetic program and further highlight the

28 redundant roles with FOXL2 to maintain fetal granulosa cell identity and combined loss of RUNX1 and F

29 R-regulated events: expansion of the cumulus granulosa cell layer that encloses the oocyte and meioti

30 polar bodies, are detached from the cumulus granulosa cell layer, and display spindle and nuclear an

31 n polyovulatory and have disrupted theca and granulosa cell layers.

32 The introduction of ZF4 mutants into a human granulosa cell line resulted in up-regulation of endogen

33 ic expression of the Jun proteins in a human granulosa cell line significantly inhibited an ovary-spe

34 er in vitro or in vivo resulted in a loss of granulosa cell morphology, function, and gene expression

35 regnant females lacking Becn1 in the ovarian granulosa cell population have a defect in progesterone

36 udy identify YAP1 as a critical regulator of granulosa cell proliferation and differentiation.

37 ression within the ovary results in impaired granulosa cell proliferation and theca cell recruitment

38 and TGF-beta signaling pathways to regulate granulosa cell proliferation, differentiation, and survi

39 a significant increase in both germ cell and granulosa cell proliferation.

40 esponding normal DNA as well as a tumor-only granulosa cell sample.

41 sa cells transition through a differentiated granulosa cell state prior to transdifferentiating towar

42 estrogen and FSH and demonstrate compromised granulosa cell survival.

43 facilitates the effect of BMP2 on somatic to granulosa cell transition.

44 novel gene-gene interactions supportive for granulosa cell tumor development were also observed betw

45 X-linked gene (Gct4) that strongly supports granulosa cell tumor development.

46 Chr) 4 (Gct1) and have revealed new loci for granulosa cell tumor susceptibility (Gct7-Gct9) on Chrs

47 8 backcross females examined, we detected 81 granulosa cell tumor-bearing animals and compared their

48 ; nevertheless, its potential involvement in granulosa cell tumorigenesis has not been examined.

49 Gct1 on Chr 4 is a fundamental oncogene for granulosa cell tumorigenesis in mice and has identified

50 d Sp1 in controlling PDGFA expression during granulosa cell tumorigenesis.

51 d Sp1 in controlling PDGFA expression during granulosa cell tumorigenesis.Oncogene advance online pub

52 ption factor is pathognomonic for adult-type granulosa cell tumors (AGCT) and a diagnostic marker for

53 Wnt/beta-catenin signaling occurs in ovarian granulosa cell tumors (GCT) and have created the Catnb(f

54 this end, human (n = 6) and equine (n = 18) granulosa cell tumors (GCT) were analyzed for beta-caten

55 in ovarian granulosa cells causes metastatic granulosa cell tumors (GCTs) in female mice and phenocop

56 on of premalignant lesions that develop into granulosa cell tumors (GCTs) spontaneously later in life

57 Granulosa cell tumors also developed in G12V mice.

58 gh prevalence of FOXL2 and KRAS mutations in granulosa cell tumors and in mucinous tumors, respective

59 ng apoptosis, leading to the accumulation of granulosa cell tumors that reactivates the epithelial pr

60 ) in mice results in an ovarian phenotype of granulosa cell tumors that renders the animals infertile

61 KRAS in Sertoli cells also caused testicular granulosa cell tumors that showed gene expression patter

62 opment of ovarian serous adenocarcinomas and granulosa cell tumors.

63 n/Kras mutant mice were infertile but lacked granulosa cell tumors.

64 mice become infertile and develop metastatic granulosa cell tumors.

65 follicles, and by ovarian dysgerminomas and granulosa cell tumors.

66 istopathological diagnosis was of a juvenile granulosa cell tumour.

67 Granulosa cell tumours of the ovary are rare, hormonally

68 ta protein in testis, ovary, lymphoid cells, granulosa cell tumours, and a subset of malignant melano

69 diffuses into the sink provided by the large granulosa cell volume, such that by 20 min the cGMP conc

70 yte Ube2i caused defects in both oocyte- and granulosa cell-expressed genes, including NOBOX and some

71 We identified the granulosa cell-secreted SDF-1 as a main chemoattractant

72 n's health and fertility, global and ovarian granulosa cell-specific androgen-receptor (AR) knockout

73 the supporting cell lineage and becomes pre-granulosa cell-specific as the gonads differentiate.

74 In vivo, granulosa cell-specific loss of Lats1/2 caused the ovari

75 tic and apoptotic cells and cells expressing granulosa cell-specific marker genes.

76 mours) and stromal tumours (such as juvenile granulosa-cell, Leydig-cell, and Sertoli-cell tumours).

77 Here, we show that TAF4b controls the granulosa-cell-specific expression of the proto-oncogene

78 man mural granulosa cells (MGCs) and cumulus granulosa cells (CGCs) was measured by mass spectrometry

79 stradiol production from primary rat ovarian granulosa cells (EC50 = 10.5 nm).

80 ivity within oocytes irreversibly transforms granulosa cells (GC), causing GC tumors (GCT) through pe

81 including WNT5a and WNT11, are expressed in granulosa cells (GCs) and are differentially regulated t

82 Despite the numerous functions executed by granulosa cells (GCs) in ovarian physiology, the role of

83 Within the ovarian follicle, granulosa cells (GCs) surround and support immature oocy

84 We used ovarian preantral granulosa cells (GCs) to elucidate the mechanism by whic

85 ignal that drives differentiation of ovarian granulosa cells (GCs).

86 ture oocytes are surrounded and supported by granulosa cells (GCs).

87 ly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells.

88 In vitro BA production by human mural granulosa cells (MGCs) and cumulus granulosa cells (CGCs

89 Preantral granulosa cells (PAGCs) differentiate into cumulus cells

90 ls, which we refer to as primordial follicle granulosa cells (pfGCs).

91 In granulosa cells 82% of identified PGR-regulated genes bo

92 olished by actinomycin D, and in transfected granulosa cells activin A stimulated ERalpha promoter ac

93 Conditional loss of endothelin receptor A in granulosa cells also decreased ovulation but did not aff

94 Granulosa cells also secrete mullerian inhibiting substa

95 nockdown of SMAD1 and SMAD5 in mouse primary granulosa cells and a human GCT-derived cell line (COV43

96 iator of the biological actions of PR in the granulosa cells and activation of its downstream pathway

97 he ovary increased in surface epithelial and granulosa cells and also in the corpora lutea of GREKO(-

98 ccelerates the differentiation of pfGCs into granulosa cells and causes premature activation of all d

99 s knocked out using CRISPR-Cas technology in granulosa cells and cultured in vitro with BMP-4 stimula

100 a dominant-stable mutant of beta-catenin in granulosa cells and develops late-onset GCT.

101 e shown to regulate both function of ovarian granulosa cells and early embryogenesis in cattle and ch

102 Positive controls as granulosa cells and HEK293 cells stably transfected with

103 In vitro treatment of primary rat granulosa cells and MLTC-1 cells with cyclic AMP (cAMP)

104 creased SR-BI mRNA expression in primary rat granulosa cells and MLTC-1 cells, whereas ACTH had no ef

105 In KGN human ovarian granulosa cells and mouse pulmonary artery smooth muscle

106 s in genes that are expressed in the somatic granulosa cells and not the oocytes.

107 ng, is spatiotemporally expressed in ovarian granulosa cells and plays a critical role in the regulat

108 nhances aromatase expression in both ovarian granulosa cells and primary preadipocytes.

109 A1 modulates aromatase expression in ovarian granulosa cells and primary preadipocytes.

110 tory follicles, we disrupted Erk1/2 in mouse granulosa cells and provide in vivo evidence that these

111 and oocytes needed for energy production by granulosa cells and required for oocyte and follicular d

112 rst genome-wide description of PGR action in granulosa cells and systematic comparison of diverse PGR

113 nt/beta-catenin signaling alters the fate of granulosa cells and that the GCT that arise in Catnb(flo

114 re differentially expressed in heat-stressed granulosa cells and the corresponding EVs, respectively.

115 determination of ovarian surface epithelium, granulosa cells and theca cells.

116 croscopy to examine entire cumulus and mural granulosa cells and their projections in mouse antral ov

117 ls in a manner specific to the population of granulosa cells and to the stage of growth and developme

118 he sources of ovarian surface epithelium and granulosa cells are known, the origin(s) of theca progen

119 preovulatory follicles is controlled by the granulosa cells around the oocyte.

120 We have used ovarian granulosa cells as a model to investigate this pathway,

121 They are synthesised by follicular granulosa cells as alpha plus betaA/betaB subunits (enco

122 tage, and the interactions of germ cells and granulosa cells basing on known and novel pathway were p

123 Thus, inappropriate activation of KRAS in granulosa cells blocks the granulosa cell differentiatio

124 n which the oocyte is coupled to surrounding granulosa cells by gap junctions.

125 Oocytes control glycolysis in granulosa cells by regulating expression levels of genes

126 he lineage specification of both Sertoli and granulosa cells by repressing Sf1 expression.

127 d antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling.

128 The cGMP is synthesized in the granulosa cells by the transmembrane guanylyl cyclase na

129 s of the FOXL2 transcription factor in adult granulosa cells can reprogram granulosa cells into Serto

130 enetic proteins (Smad1 and Smad5) in ovarian granulosa cells causes metastatic granulosa cell tumors

131 nse to luteinizing hormone (LH), cGMP in the granulosa cells decreases, and as a consequence, oocyte

132 and selected disruption of the Cebpb gene in granulosa cells demonstrate that C/EBPbeta (CCAAT/Enhanc

133 Aromatase expression in ovarian granulosa cells dictates levels of circulating estrogen

134 Thus, preantral granulosa cells differ from cumulus cells in CEEF-depend

135 d functional changes that occur as preantral granulosa cells differentiate into cumulus cells.

136 Cyclic GMP (cGMP) generated in the granulosa cells diffuses through gap junctions into the

137 ever, constitutive expression of KrasG12D in granulosa cells disrupted normal follicle development le

138 Importantly, the loss of TAF4b in ovarian granulosa cells disrupts cellular morphologies and inter

139 That KrasG12D/Pten mutant granulosa cells do not transform but rather undergo cell

140 Therefore, preantral granulosa cells do not undergo expansion for two fundame

141 latory surge of gonadotropins, but preantral granulosa cells do not.

142 functional interactions of these pathways in granulosa cells during follicular development in vivo, w

143 To analyze the functions of RAS protein in granulosa cells during ovarian follicular development in

144 in the differentiation of somatic cells into granulosa cells during primordial follicle formation.

145 Inactivation of Lats1/2 in murine granulosa cells either in vitro or in vivo resulted in a

146 Taking together, EVs generated from granulosa cells exposed to HS has the potential to shutt

147 Results showed that granulosa cells exposed to HS increased the accumulation

148 nditional knock-in mouse models in which the granulosa cells express a constitutively active KrasG12D

149 ygen species, and apoptosis were observed in granulosa cells from aged women.

150 omplete dynamic genetic programs of germ and granulosa cells from E16.5 to postnatal day (PD) 3 were

151 By contrast, granulosa cells from similar preantral follicles possess

152 For this, bovine granulosa cells from smaller follicles were cultured in

153 ementation of stress-related EVs in cultured granulosa cells has induced adaptive response to subsequ

154 se following formation of multiple layers of granulosa cells have two major fates: either to continue

155 tes regulate glycolysis and the TCA cycle in granulosa cells in a manner specific to the population o

156 e central role of cyclic GMP (cGMP) from the granulosa cells in maintaining meiotic arrest, but it is

157 Podoplanin was also strongly expressed by granulosa cells in normal ovarian follicles, and by ovar

158 the cellular and EV-coupled miRNAs of bovine granulosa cells in response to HS.

159 ds, including Leydig cells in the testes and granulosa cells in the ovaries.

160 actor in adult granulosa cells can reprogram granulosa cells into Sertoli cells.

161 resses Sox9 to block transdifferentiation of granulosa cells into Sertoli-like cells in the adult mou

162 ne Foxl2 and reprogrammed juvenile and adult granulosa cells into Sertoli-like cells, triggering form

163 ercellular communication between oocytes and granulosa cells is essential for normal follicular diffe

164 Timely expression and activation of YAP1 in granulosa cells is essential for ovarian follicle develo

165 dependent expression of aromatase in ovarian granulosa cells is inversely correlated with the protein

166 The cell cycle recruitment of granulosa cells is regulated at least in part by hormone

167 sient but not sustained activation of RAS in granulosa cells is therefore crucial for directing norma

168 Because disrupting Pten in granulosa cells leads to increased proliferation and sur

169 at indeed, inactivation of the Brca1 gene in granulosa cells led to the development of cystic tumors

170 so in embryonic gonads and in spermatids and granulosa cells of adult testes and ovaries, respectivel

171 inge and lunatic fringe are expressed in the granulosa cells of developing follicles.

172 found to be expressed stage specifically in granulosa cells of goats.

173 ls of embryonic testes from 12.5 dpc, and in granulosa cells of growing follicles in adult ovaries.

174 Mullerian hormone/AMH), which is produced by granulosa cells of growing follicles, has been proposed

175 evated levels of phospho-AKT were evident in granulosa cells of immature KrasG12D mice, even in the a

176 hly expressed in cumulus cells than in mural granulosa cells of mouse antral follicles.

177 Unlike granulosa cells of normal ovaries, most (15 of 24) GCT s

178 y, we showed that ER stress was activated in granulosa cells of PCOS patients as well as in a well-es

179 ells, and their expression also increased in granulosa cells of PCOS patients.

180 iently produced prior to follicle rupture by granulosa cells of periovulatory follicles and induces o

181 er-driven knockout of Yap1 in differentiated granulosa cells of preovulatory follicles and luteal cel

182 ses 1 and 2) are activated by an LH surge in granulosa cells of preovulatory follicles, we disrupted

183 the role of mTOR signaling and KIT ligand in granulosa cells of primordial follicles for follicle act

184 ominate in the cortex and differentiate into granulosa cells of quiescent primordial follicles.

185 KrasG12D induced cell cycle arrest in granulosa cells of the KrasG12D;Cyp19-Cre mice but not i

186 ormone (LH) activates receptors in the mural granulosa cells of the ovarian follicle.

187 equires productive interactions with somatic granulosa cells of the ovarian follicle.

188 mone (FSH) receptor is expressed only in the granulosa cells of the ovary and the Sertoli cells of th

189 amma) as a target of regulation by PR in the granulosa cells of the preovulatory follicles during the

190 These findings suggest that ER stress in granulosa cells of women with PCOS contributes to the in

191 l process most represented in germ cells and granulosa cells or common to both cell types at each spe

192 dal supporting cells into either ovarian pre-granulosa cells or testicular Sertoli cells.

193 endogenous pH(i) regulation, and reveal that granulosa cells possess multiple mechanisms for carrying

194 pathway caused by the decrease in INPP4B in granulosa cells promotes an ovarian environment defectiv

195 Production of Dhh/Ihh in granulosa cells requires growth differentiation factor 9

196 promoter-driven knockout of Yap1 in ovarian granulosa cells resulted in increased apoptosis of granu

197 The cGMP decrease in the granulosa cells results in rapid cGMP diffusion out of t

198 signaling effector beta-catenin (CTNNB1) in granulosa cells results in the formation of premalignant

199 We report that in the absence of FSH, granulosa cells secrete a subthreshold concentration of

200 reverse transcription-PCR assays on cultured granulosa cells showed that both ERalpha and ERbeta mRNA

201 viability upon modulation of BMPR-IB gene in granulosa cells similar to that are documented in sheep

202 Proliferating granulosa cells support the progression of follicular gr

203 ctivin beta A-expressing germ cells; (c) pre-granulosa cells surrounding primordial follicles.

204 aintained by cyclic GMP from the surrounding granulosa cells that diffuses into the oocyte through ga

205 Here we describe two AR-mediated pathways in granulosa cells that regulate ovarian follicular develop

206 cytes and FSH in the transition of preantral granulosa cells to cumulus cells competent to undergo ex

207 MAPKs were activated by EGF in preantral granulosa cells to essentially the same levels as in cum

208 yte pH(i), indicate that gap junctions allow granulosa cells to exogenously regulate oocyte pH(i) aga

209 To assess the competence of preantral granulosa cells to generate responses associated with ex

210 supports the proliferation of differentiated granulosa cells to keep up with the demand of cells to c

211 zing hormone then acts on receptors in outer granulosa cells to rapidly decrease cGMP.

212 dings could explain the distinct response of granulosa cells to T and DHT and provide a molecular mec

213 fects may involve a differential response of granulosa cells to the androgens testosterone (T) and di

214 Preantral granulosa cells treated with EGF, but not those treated

215 proliferation and viability was observed in granulosa cells upon BMPR-IB modulation.

216 We propose that granulosa cells use cytoplasmic projections to search fo

217 Here we characterised PGR activity in mouse granulosa cells using combined ChIP-seq for PGR and H3K2

218 pressed in theca cells, triggers a signal in granulosa cells via apolipoprotein E receptor 2 and the

219 s" latent GDF9, enabling potent signaling in granulosa cells via type I receptors (i.e. activin recep

220 hermore, differentiation of both Sertoli and granulosa cells was blocked when Wt1 was deleted before

221 Metabolic coupling between oocytes and granulosa cells was not affected in follicles from the s

222 Granulosa cells were also found to possess a V-type H(+)

223 Mural granulosa cells were found to possess randomly oriented

224 dominant stable beta-catenin mutant in their granulosa cells were generated.

225 The F3 generation granulosa cells were isolated and found to have a transg

226 8-fold by transient co-transfection of human granulosa cells with a Wt1 expression construct.

227 FSH acts on granulosa cells within the immature follicle to inhibit

228 within the developing follicles (oocytes and granulosa cells), and their ovarian mRNA levels increase

229 d in luteal cells (terminally differentiated granulosa cells).

230 liferation, differentiation and apoptosis in granulosa cells, and consequently, small abnormal follic

231 /5 leads to upregulation of PDGFA in ovarian granulosa cells, and that a novel regulatory interaction

232 /5 leads to upregulation of PDGFA in ovarian granulosa cells, and that a novel regulatory interaction

233 sforming growth factor (TGF)-beta1, in human granulosa cells, and their expression also increased in

234 s prevents the differentiation of pfGCs into granulosa cells, and this arrests the dormant oocytes in

235 osa cells resulted in increased apoptosis of granulosa cells, decreased number of corpora lutea, redu

236 Following selective ablation of Edn2 in granulosa cells, Esr2-Edn2KO dams had reduced oocytes ov

237 cond, activation of MAPKs alone in preantral granulosa cells, even in the presence of CEEFs, is not s

238 al profiles of six main cell types; oocytes, granulosa cells, immune cells, endothelial cells, periva

239 of each follicular cell type (i.e., oocyte, granulosa cells, including cumulus and mural cells), dur

240 ignaling specific to early-stage oocytes and granulosa cells, indicative of oxidative damage as a cru

241 dhesion modulates self-assembly of human KGN granulosa cells, normal human fibroblasts (NHFs), and MC

242 ported expression of genes by germ cells and granulosa cells, our analyses identified 5 distinct cell

243 follicle-stimulating hormone-treated ovarian granulosa cells, resulting in enhanced progesterone synt

244 in breast cancer, thyroid, and preovulatory granulosa cells, suggesting that the PKA-dependent depho

245 e carrying a Brca1 mutation in their ovarian granulosa cells, two thirds of which develop ovarian or

246 From a microarray study on mouse ovarian granulosa cells, we discovered that the estrogen recepto

247 anti-proliferative effects of KRAS(G12D) in granulosa cells, we sought to determine whether KRAS(G12

248 (c)GMP into the oocyte from the surrounding granulosa cells, where it is produced by the guanylyl cy

249 was predominantly expressed in proliferative granulosa cells, whereas the inactive form of YAP1 (cyto

250 ocyte growth is supported by theca cells and granulosa cells, which establish dynamic and highly orga

251 sdifferentiate into their female equivalents-granulosa cells-and testicular tissue reorganizes to a m

252 SMAD2/3-responsive transcriptional assays in granulosa cells.

253 n, cGMP begins to decrease in the peripheral granulosa cells.

254 s due to defective proliferation of cuboidal granulosa cells.

255 edgehog (Dhh) and Indian hedgehog (Ihh) from granulosa cells.

256 usters associated with germ cells and 6 with granulosa cells.

257 of luteinizing hormone (LH) receptor by the granulosa cells.

258 rsor cells into male Sertoli cells or female granulosa cells.

259 ding somatic cells, which differentiate into granulosa cells.

260 as a coreceptor in the signaling complex in granulosa cells.

261 ranslation, and initiates differentiation of granulosa cells.

262 lular PI3 Kinase/AKT signaling in follicular granulosa cells.

263 ates Foxl2 and reprograms Sertoli cells into granulosa cells.

264 ate into testicular Sertoli cells or ovarian granulosa cells.

265 nase (MAPK) increased markedly in the mutant granulosa cells.

266 2, Smad3, or both Smad2 and Smad3 in ovarian granulosa cells.

267 d the regulation of target genes in cultured granulosa cells.

268 was deleted via Cre-Lox-mediated excision in granulosa cells.

269 recover from acidosis in a manner resembling granulosa cells.

270 ased apoptosis or decreased proliferation of granulosa cells.

271 ing the pretumoral lesions but not to normal granulosa cells.

272 n addition, many follicles contain apoptotic granulosa cells.

273 6 mRNA was minimally stimulated in preantral granulosa cells.

274 n of the aromatase gene (CYP19A1) in ovarian granulosa cells.

275 l cancers indirectly, by influencing ovarian granulosa cells.

276 o inactivate the Brca1 gene in mouse ovarian granulosa cells.

277 in DF-1, LMH, LMH/2A, and primary theca and granulosa cells.

278 anscription of the aromatase gene in ovarian granulosa cells.

279 ly, possibly through an effector secreted by granulosa cells.

280 germ cells were revealed, as well as for the granulosa cells.

281 rther highlight the remarkable plasticity of granulosa cells.

282 te along a distinct pathway to become wave 1 granulosa cells.

283 ed by a reduction in TGF-beta1 expression in granulosa cells.

284 to form ovarian FLCs, including oocytes and granulosa cells.

285 In the ovary, Fxna mRNA is expressed in granulosa cells; its abundance is maximal 48 hours after

286 eta-catenin pathway are expressed in ovarian granulosa cells; nevertheless, its potential involvement

287 ls and native LH receptors on both KGN human granulosa-derived tumor cells and M17 human neuroblastom

288 f AVT ISH-labeled neurons matched that of T. granulosa, except in the lateral septum, ventral hypotha

289 comitans, Campylobacter spp., Capnocytophaga granulosa, G. morbillorum, P. micra, Porphyromonas endod

290 spp, Campylobacter gracilis, Capnocytophaga granulosa, Haemophilus parainfluenzae, and Lautropia mir

291 arlier study in rough-skinned newts (Taricha granulosa) indicated that the neuroanatomical distributi

292 rs and Sertoli cells transdifferentiate into granulosa-like cells.

293 pread distribution of AVT-ir is unique to T. granulosa or a feature common among salamanders.

294 patric prey, the rough-skinned newt (Taricha granulosa), Sierra newt (Ta. sierrae) and California new

295 ssues, isolated ovarian steroidogenic cells (granulosa, theca, small luteal, and large luteal), and i

296 ds that activate EGF receptors (EGFR) on the granulosa, thereby initiating the ovulatory events.

297 olutionary arms race induces variation in T. granulosa TTX levels, from very high to undetectable.

298 Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated

299 Comparison of granulosa, uterus and oviduct PGR-dependent genes showed

300 C. ochracea (and variant) and C. granulosa were the most prevalent species.