ライフサイエンスコーパス: growth hormone receptor

1 ased on an archetypal cytokine receptor, the growth hormone receptor.

2 gonist and can bind only one molecule of the growth hormone receptor.

3 ed to the ligand binding determinants of the growth hormone receptor.

4 development in vitro and in vivo, as did the growth hormone receptor, a nonhematopoietic receptor.

5 ically engineered pig with a knockout of the growth hormone receptor and addition of 6 human transgen

6 Changes in growth hormone receptor and IGF-I mRNA expression may ac

7 Growth hormone receptor and IGF-I mRNA levels were reduc

8 n of human erythropoietin receptor and human growth hormone receptor and is supported by evidence sho

9 ed in signaling pathways found downstream of growth hormone receptor and receptor tyrosine kinases, i

10 re variation in Europeans and for genes with growth hormone receptor and regulation functions.

11 my, or growth hormone replacement on CYP2C6, growth hormone receptor, and growth hormone-binding prot

12 ncident type 2 diabetes were aminoacylase-1, growth hormone receptor, and insulin-like growth factor-

13 lso uncommon in humans with mutations in the growth hormone receptor, and natural genetic variants in

14 0A4, S100A6, c-Myb, estrogen receptor alpha, growth hormone receptor, and progesterone receptor were

15 e regulator and rodent alpha2-macroglobulin, growth hormone receptors, and insulin-like growth factor

16 emerging somatostatin receptor ligands, the growth hormone receptor antagonist pegvisomant and the d

17 and pasireotide), dopamine agonists and the growth hormone receptor antagonist pegvisomant.

18 a co-chaperone and regulator of androgen and growth hormone receptor (AR, GHR) signalling.

19 ul5-Rbx2 (CRL5(SOCS2)), binds phosphorylated growth hormone receptor as its main substrate.

20 rant nature of the guinea-pig growth hormone-growth hormone receptor axis is due to these replacement

21 r cytokines, the extracellular domain of the growth hormone receptor circulates as a binding protein,

22 ons such as caloric restriction, ablation of growth hormone receptors, consumption of high-fat diets,

23 Site-directed antibodies to the growth hormone receptor could be potentially useful as g

24 .SIGNIFICANCE STATEMENT People and mice with growth hormone receptor deficiency (GHRD or Laron syndro

25 Growth hormone receptor deficiency (GHRD) results in sho

26 y alternative splicing or proteolysis of the growth hormone receptor extracellular domain (ECD).

27 ets KIR apart from the C2-type hematopoietic growth hormone receptor fold.

28 quence were found to lead to upregulation of growth hormone receptor gene (Ghr) expression in transdu

29 The common deletion of the third exon of the growth hormone receptor gene (GHRd3) in humans is associ

30 This includes down-regulation of growth hormone receptor (GHR) and of STAT5 signaling, wh

31 Growth hormone receptor (GHR) and prolactin receptor (PR

32 Growth hormone receptor (GHR) endocytosis is a highly re

33 To clarify the divergence of the growth hormone receptor (GHR) family, we characterized a

34 ce caused by cytokine-induced suppression of growth hormone receptor (GHR) gene expression.

35 an important mechanism for the regulation of growth hormone receptor (GHR) gene expression.

36 The growth hormone receptor (GHR) gene in cattle is expresse

37 the muscle, we specifically inactivated the growth hormone receptor (ghr) gene in postnatal mouse sk

38 A portion of the rat growth hormone receptor (GHR) gene was cloned by PCR.

39 vine riboprobes, expression of the IGF-I and growth hormone receptor (GHR) genes was examined in ovin

40 The growth hormone receptor (GHR) is a cell surface receptor

41 Growth hormone receptor (GHR) is a cytokine receptor sup

42 We identified growth hormone receptor (GHR) is mainly expressed in mes

43 elopmental and tissue-specific regulation of growth hormone receptor (GHR) mRNA expression is complex

44 Growth hormone receptor (Ghr) signaling is important in

45 rtial hepatectomy by preventing increases in growth hormone receptor (GHR) via ubiquitination, suppre

46 The growth hormone receptor (GHR), a cytokine receptor super

47 Plasma insulin-like growth factor-1 (IGF-1), growth hormone receptor (GHR), and insulin-like growth f

48 ted model of tissue-specific deletion of the growth hormone receptor (GHR).

49 improvement in HbA1c, which was mediated by growth hormone receptor (GHR).

50 ing group, while IGF-1-related genes [Igf1 / growth hormone receptor (Ghr)] decreased slightly (7%).

51 lication FDR-corrected p = 2.18 x 10-2), and growth hormone receptor (GHR, Discovery FDR-corrected p

52 with phosphorylated peptides from substrates growth hormone receptor (GHR-pY595) and erythropoietin r

53 disruptions in the somatotropic axis such as growth hormone receptors have an impact on DNAm maximum

54 n growth hormone (hGH) variants to the human growth hormone receptor (hGHR) and the human prolactin r

55 Two isoforms of the human growth hormone receptor (hGHR), which differ in the pres

56 biting the interaction of hGH with the human growth hormone receptor (hGHR).

57 ve been previously noted in meningiomas (eg, growth hormone receptor, IGFBP-7, endothelin receptor A,

58 ll set of contacts are crucial for the human growth hormone-receptor interaction.

59 In both groups, growth hormone receptor mRNA expression was examined by

60 sion of growth hormone-releasing hormone and growth hormone-receptor mRNAs in the arcuate nucleus (AR

61 rf mouse models, including Ames, Little, and growth hormone receptor-null mice.

62 utated the extracellular domain of the ovine growth hormone receptor (oGHR) to the corresponding amin

63 es using beads decorated with phosphorylated growth hormone receptor peptides.

64 The exon 3-deleted growth hormone receptor polymorphism (GHR(d3)) may accou

65 tisera generated using peptides derived from growth hormone receptor sequences failed to recognize th

66 Whereas CHO cells expressing the growth hormone receptor showed marked downregulation of

67 quired for ligand-induced endocytosis of the growth hormone receptor, suggesting that ubiquitin-depen

68 y of epitope-switching between rat and ovine growth hormone receptors to produce rat epitopes in the

69 In contrast to the growth hormone receptor, we found that the initial endoc

70 arison of the structure to that of the human growth hormone receptor, which belongs to a different cl