ライフサイエンスコーパス: guanine phosphoribosyltransferase

1 des the purine recycling enzyme hypoxanthine-guanine phosphoribosyltransferase.

2 sed by deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase.

3 hosphate dehydrogenase (GAPDH), hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT1), DNA-directe

4 lanation for the specificity of hypoxanthine-guanine phosphoribosyltransferase, a key enzyme in the p

5 Mutants deficient in hypoxanthine-xanthine-guanine phosphoribosyltransferase activity were used as

6 utant parasite lacking hypoxanthine-xanthine-guanine phosphoribosyltransferase and a T. gondii cDNA l

7 ynthesis and relies primarily on adenine and guanine phosphoribosyltransferases (APRTase and GPRTase)

8 inical features associated with hypoxanthine-guanine phosphoribosyltransferase deficiency.

9 s and diagnosis of all forms of hypoxanthine-guanine phosphoribosyltransferase deficiency.

10 Guanine phosphoribosyltransferase from Giardia lamblia,

11 The Escherichia coli xanthine-guanine phosphoribosyltransferase gene (Ecogpt) rescues

12 on of 8 x 10(-3) in the nuclear hypoxanthine-guanine phosphoribosyltransferase gene, and a clear and

13 cell death and mutations at the hypoxanthine-guanine phosphoribosyltransferase gene.

14 ely stable mutation rate of the hypoxanthine-guanine phosphoribosyltransferase gene.

15 The coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene was amplified by

16 adenine phosphoribosyltransferase (APRT) and guanine phosphoribosyltransferase (GPRT) that constitute

17 Guanine phosphoribosyltransferase (GPRTase) from Giardia

18 tains the selectable marker Escherichia coli guanine phosphoribosyltransferase (gpt) linked to a TGFb

19 Homozygous null mutants of the hypoxanthine-guanine phosphoribosyltransferase (hgprt) and adenine ph

20 to be good inhibitors of human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Plasmodium

21 d identity with the L. donovani hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and significan

22 vages purines primarily through hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and xanthine p

23 horibosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT) are two struct

24 We here demonstrate that human hypoxanthine guanine phosphoribosyltransferase (HGPRT) converts T-705

25 complexes of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase (HGPRT) have been dete

26 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is a key enzym

27 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is the key enz

28 activity was determined at the hypoxanthine-guanine phosphoribosyltransferase (HGPRT) locus.

29 es of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) of the apicomp

30 Crystal structures of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) proteins have

31 To dissect the contributions of hypoxanthine-guanine phosphoribosyltransferase (HGPRT), adenine phosp

32 ucture of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase (HGPRT)-xanthosine 5'-

33 y of the purine salvage enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

34 HGXPRT) and Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

35 des the purine recycling enzyme hypoxanthine-guanine phosphoribosyltransferase (HGprt).

36 or direct salvage of guanine by hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

37 of the purine recycling enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt).

38 ents with LND and its variants (hypoxanthine-guanine phosphoribosyltransferase [HGprt]-related neurol

39 leoside phosphorylase (PNP) and hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) catalyze N-

40 Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) catalyzes t

41 e are similar to those of human hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) despite dis

42 Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) is the locu

43 lations on two enzymes: a human hypoxanthine-guanine-phosphoribosyltransferase (HGPRTase) and its ana

44 the purine biosynthetic enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) cause the intra

45 Somatic mutations in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene are rare o

46 onal promoter and exon 1 of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the mou

47 ced mutation frequencies at the hypoxanthine guanine phosphoribosyltransferase (HPRT) locus in diploi

48 sociated with cRSS sites at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in periph

49 rder caused by mutations of the hypoxanthine guanine phosphoribosyltransferase (HPRT) purine biosynth

50 mutations were detected in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) reporter gene i

51 Here we present the hypoxanthine-guanine phosphoribosyltransferase (HPRT) reporter gene m

52 guanine through the activity of hypoxanthine-guanine phosphoribosyltransferase (HPRT) to supply the c

53 somatic mutations (Mfs) at the hypoxanthine-guanine phosphoribosyltransferase (HPRT)-reporter gene i

54 cy of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

55 the X chromosome-linked enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

56 mphoblastoid cells in the human hypoxanthine-guanine-phosphoribosyltransferase (HPRT) gene and compar

57 These genes included those for hypoxanthine-guanine phosphoribosyltransferase (hpt), adenylosuccinat

58 defined by the enzymes hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) and adenosine

59 xpression of T. gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) in stable tra

60 tive selectable marker hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT).

61 with 17alpha or Yalpha and the hypoxanthine guanine phosphoribosyltransferase locus (HPRT1).

62 ransgene (Tg; inserted into the hypoxanthine-guanine phosphoribosyltransferase locus) that enables in

63 sing a knock-in approach at the hypoxanthine-guanine phosphoribosyltransferase locus, we generated a

64 One potential new target is hypoxanthine-guanine phosphoribosyltransferase (MtHGPRT), a key enzym

65 ated a cell line derived from a hypoxanthine-guanine phosphoribosyltransferase negative (HPRT-) HT108

66 leoside phosphorylase (PNP) and hypoxanthine-guanine phosphoribosyltransferase to form guanine ribonu

67 lases, guanosine deaminase, and hypoxanthine guanine phosphoribosyltransferase, we demonstrate that p

68 and Arg(63), in contrast to the hypoxanthine-guanine phosphoribosyltransferases, which use two Mg2+ i

69 possess two purine salvage enzymes: xanthine-guanine phosphoribosyltransferase (XGPRT) and hypoxanthi