ライフサイエンスコーパス: guide

1 ids and then with the aid of a simple visual guide.

2 and a previously developed model of droplet guiding.

3 We report a method called 'tomography-guided 3D reconstruction of subcellular structures' (TYG

4 Mechanically guided, 3D assembly has attracted broad interests, owing

5 proved the feasibility of retrosynthetically guided access to synthetic Taxol, albeit in minute quant

6 ence for phase-amplitude coupling mechanisms guiding action selection during emotional-action control

7 This will guide additional testing.

8 The tool guided an MI-based conversation between coach and patien

9 study, low- intensity collimated ultrasound-guided anatomic mapping and robotic ablation allows PV i

10 source attribution at subfacility scales to guide and verify effective mitigation policy and action.

11 as achieved using a single guide RNA (sgRNA)-guided and catalytically impaired Campylobacter jejuni C

12 se assembled, we determine which features of guides and their targets best predict activity and how t

13 The droplet guiding and sorting experiments are complemented by mode

14 on phase manipulation, such as external beam guiding, and present a new method for measuring the nonl

15 Data on clinical algorithms to guide antibiotic cessation are limited.

16 We provide a narrative review of evidence to guide antibiotic duration in sepsis.

17 ved diagnostic/risk prediction strategies to guide antibiotic prescribing for suspected UTI in older

18 .85]; p < 0.001), but not clinical algorithm-guided antibiotic therapy (-7.41 [-18.18 to 3.37]; p = 0

19 1 [0.82-1.01]; p = 0.09), clinical algorithm-guided antibiotic treatment (0.67 [0.30-1.54]; p = 0.35)

20 Neither procalcitonin-guided antibiotic treatment (0.91 [0.82-1.01]; p = 0.09)

21 yped group) or no genotyping (usual care) to guide antiplatelet drug selection.

22 1 complex and describe its essential role in guiding apical polarization and zonula adherens formatio

23 -read sequencing with a Hi-C-based proximity guided assembly to generate a 15.87 Mb assembly of the Y

24 CLOSE-guided atrial fibrillation (AF) ablation is based on con

25 his process is critical in helping organisms guide attention toward the most salient and novel featur

26 ward writing tips-and a web tool, PubReCheck-guiding authors to help address the most common cases th

27 CRISPR-Cas-guided base editors convert A*T to G*C, or C*G to T*A, i

28 w the brain processes sensory information to guide behavior, we must know how stimulus representation

29 ntion-predicts the quality of ensuing memory-guided behavior.

30 nished the influence of salience on visually guided behavior.

31 C, two regions that are important for memory-guided behaviors, in two tasks: one where attention was

32 able coding scheme simplifies readout for WM-guided behaviour, whereas the low-dimensional dynamic co

33 ng MeDeCom, RefFreeCellMix or EDec and (iii) guided biological inference and validation of deconvolut

34 tunities for molecular diagnostics and image-guided biomedical applications.

35 We were able to perform CT-guided biopsies with histologic validation of the nonres

36 ents, of whom 216 underwent (18)F-FDG PET/CT-guided biopsy and 125 underwent CT-guided biopsy.

37 ackground Digital breast tomosynthesis (DBT)-guided biopsy is increasingly used in practice.

38 An overall disease upgrade by in-bore MRI-guided biopsy occurred in 40% (16 of 40) of cases (61.5%

39 cancer detection rate when using in-bore MRI-guided biopsy was 65% (26 of 40).

40 cases with positive results from in-bore MRI-guided biopsy).

41 , focus surgical resection, and enable image-guided biopsy.

42 DG PET/CT-guided biopsy and 125 underwent CT-guided biopsy.

43 to determine the success rate of (68)Ga-PSMA-guided bone biopsies for molecular diagnostics in mPC pa

44 Simulations are guided by a phylogenetic tree and incorporate different

45 ed whether frequent insulin dose adjustments guided by an automated artificial intelligence-based dec

46 Model selection was guided by backward stepwise selection conducted on the m

47 proaches in childhood cancers, few have been guided by biomarkers or clinical-grade assays developed

48 represents generations of scientific inquiry guided by careful observation and occasional serendipity

49 However, decisions are not guided by choice-linked reward associations alone; macaq

50 Guided by chromatin structure, through the use of Chromo

51 gests immunotherapy administration should be guided by clinical features of encephalitis, rather than

52 To obtain this structure, we were guided by findings from single-molecule fluorescence spe

53 viors, in two tasks: one where attention was guided by memory and another in which attention was expl

54 Guided by metabolism studies, we identified compounds wi

55 ly less important, as foragers are primarily guided by olfactory information.

56 w, it has been unclear how the origin DNA is guided by ORC-Cdc6 and inserted into the Mcm2-7 hexamer.

57 h stage 5 CKD who want to avoid dialysis, is guided by patient values, preferences, and goals, with a

58 m (AI-DSS) is as effective and safe as those guided by physicians in controlling glucose levels.

59 Guided by previous structural studies, we hypothesized t

60 Guided by the AHA's new Mission Statement, to be a relen

61 Guided by the early findings of social scientists, pract

62 eering where the differentiation of cells is guided by the scaffold and signals, a bottom-up method i

63 suggesting that DNA methylation patterns are guided by the sequence preference of these enzymes.

64 fabricate customized scaffolds and surgical guides by 3D printing.

65 With literature-guided causal inference tools, >300 site-specific signal

66 nsduction and as a regulator of mechanically guided cell migration.

67 d multivariate statistics can be employed to guide chemical analysis, to improve de-replication, and

68 and OSAS could help to stratify treatments, guiding choice towards those which most effectively reso

69 erent mechanisms of action, which could help guide clinical decision making in the management of pati

70 renal cell carcinoma aggressiveness may help guide clinical decision-making.

71 , novel diagnostic tools can be developed to guide clinical diagnosis of contact allergies.

72 We aim to guide clinicians and researchers to consider sex and gen

73 e 2-position that was optimized by structure-guided compound design.

74 provides important prognostic information to guide counseling of affected families with cardiovascula

75 sed to understand overall trends rather than guide country-specific allocation.

76 Conclusion Percutaneous CT- and MRI-guided cryoablation of cT1 renal cell carcinoma had simi

77 Many parts of the visuomotor system guide daily hand actions, like reaching for and grasping

78 ic, stable, and abundant target for affinity-guided delivery of anticancer drugs.

79 -6 and RAMOS cells in terms of the number of guides depleted in library screening and the extent of t

80 y and how to best combine them into a single guide design algorithm.

81 Our results show the value of model-guided design as an approach for generating useful DNA p

82 Here, using structure guided design of the murine STING CDN binding domain, we

83 eyond their synaptic partners such that they guide development before the onset of vision.

84 i-centre hospital outpatient population, and guide development of an evidence-based threshold for opt

85 other emerging pathogens, knowledge that may guide development of effective antiviral therapies.

86 ropriately reduced intrinsic efficacy should guide development of safer opioids.

87 ures, course, and outcomes of AFM to help to guide diagnosis, management, and rehabilitation.

88 y in the areas that are active during memory-guided direction comparisons, area MT and the prefrontal

89 sively changes as the Pol II moves along the guide DNA.

90 Deployment of RNA-guided DNA endonuclease CRISPR-Cas technology has led to

91 A conventional DnCNN was modified into a guided DnCNN, which uses the low b-value DW image as a g

92 , 25 mg of OM BID, or to pharmacokinetically guided dose titration (OM-PK) for 20 weeks.

93 lay out an important framework for structure-guided drug discovery targeting MCTs.

94 umans engage in social epistemic actions, to guide each other's attention, prediction, and learning p

95 apping and electroanatomical voltage mapping-guided endomyocardial biopsy showed low endocardial volt

96 erforms conformational sampling and template-guided energy refinement to produce a variety of possibl

97 eef geography and its human impacts, thereby guiding environmental management for reef resiliency.

98 he possibility of using IL-6 or CRP level to guide escalation of treatment in patients with COVID-19-

99 ional alanine-scanning mutagenesis (CASM) to guide experiments.

100 engthening encoding of novel information and guiding exploration based on prior experience.

101 gy, we found that AcrVIA1 interacts with the guide-exposed face of Cas13a, preventing access to the t

102 ting that the hippocampus coordinates memory-guided eye movements.

103 -based amelogenin nanoribbons are capable of guiding fibrous apatite nanocrystal formation.

104 Computed tomography-guided fine-needle aspiration for Gram stain and culture

105 lding landscape and discuss the factors that guide folding in vitro and in vivo We particularly focus

106 This review is intended to be a practical guide for the clinician facing a patient with food prote

107 G protein coupled receptor (GPCR), Tre1, to guide front-back migratory polarity radially from the cl

108 Since RNA elements guide function in most RNA viruses, and they represent p

109 ed central areas of future investigations to guide further efforts to implement ultrasensitive resist

110 a critical period of brain development could guide further investigation into sex-dependent mechanism

111 ts explanation and elaboration document, may guide future analyses and reporting of RCTs.

112 The scientific findings of this work could guide future exploration of next-generation field-deploy

113 These data will guide future modifications and improvements of H129-base

114 omic factors of irrigation expansion and may guide future research and resources toward those agricul

115 om other coronaviruses can provide clues and guide future research.

116 instem gliomagenesis and classification, and guide future studies for the development of novel treatm

117 Utilizing historical clinical datasets to guide future treatment choices is beneficial for patient

118 x roles of antibodies in viral entry and can guide future vaccine design and antibody-based drug ther

119 lopment of correlates of protection that may guide future vaccine trials.

120 g the phase-structure-property relationship, guiding future design and synthesis of nanoparticles for

121 ure concentrations of airborne microplastics guiding future toxicological assessments.

122 e revealed principles of gene regulation and guided genetic variation analysis.

123 n regions may coordinate during the visually guided grasping of objects.

124 most involved airways in the first session (guided group) or a standard three-session BT (unguided).

125 Guidance cues act during development to guide growth cones to their proper targets in both the c

126 fields that govern PCET thermochemistry may guide heterogeneous catalyst design.

127 rs that can generate NCE contingencies while guiding how research might better anticipate and account

128 In conflict settings, data to guide humanitarian and development responses are often s

129 Together, our results show that memory-guided identity templates proactively impact perception

130 erely a tissue "background" but specifically guide immune cells both in development and pathology.

131 ted molecular pattern on host cells that may guide immune responses leading to the concomitant damage

132 ty about future rewards and propose how they guide information-seeking, attention, decision-making, a

133 gate whether predispositions for uncertainty-guided information seeking relate to individual differen

134 is pursuit, cancer health equity remains the guiding institutional principle that applies to all its

135 tively read fluorescent margins with a short guided instruction, highlighting clinical adaptability.

136 This article reviews work on how search is guided intelligently.

137 This framework's refinement and use will guide interdisciplinary study around sanitation to ident

138 in the transition from health to leukemia to guide interpretation of changes in the transcriptome as

139 ty in characterizing high-risk survivors and guiding intervention strategies.

140 meaningful metric for risk stratification to guide interventions remains a challenge.

141 Machine learning (ML) may guide interventions to reduce this risk.

142 ion recovery (FLAIR) estimates lesion age to guide intravenous thrombolysis.

143 receiving optical coherence tomography (OCT)-guided intravitreal injections.

144 Association (AHA) develops an Impact Goal to guide its overall strategic direction and investments in

145 n novel visuospatial discriminations (reward-guided learning).

146 duction, serve as environmental sentinels or guide living therapeutics.

147 advance our understanding of the mechanisms guiding lyase isomerases.

148 isualizing metastasis and performing imaging-guided lymph node surgery is challenging.

149 Results demonstrate that combinatory AQbD-guided mass spectrometric/liquid chromatographic optimiz

150 This framework guides mechanistic inference by directing functional val

151 eatment of recurrent depression, and the MRI-guided method of coil targeting is not better than the s

152 f these data-driven models should be used to guide model building.

153 ments and simulations show the excitation of guided modes by the electron beam and their efficient de

154 icroscopy experiments which could be used to guide molecular design for stability.

155 al spatial signals into representations that guide motor responses.

156 al spatial signals into representations that guide motor responses.SIGNIFICANCE STATEMENT In our natu

157 Structure-guided mutagenesis and docking studies demonstrate the i

158 e protease activity, we employed a structure-guided mutagenesis approach and identified residues that

159 state of the brain are important for memory-guided navigation and rely on visual inputs.

160 s with specific miRNA expression using miRNA-guided neuron tags (mAGNET).

161 ity progress in automated spike sorting, and guides neuroscientists to an optimal choice of sorter an

162 In this study, we used the RNA-guided nuclease CRISPR-Cas9 (clustered regularly-intersp

163 onstrates how active learning can be used to guide omics data collection for training predictive mode

164 ctional treadmill in which participants were guided on two sides of a triangle and then found their b

165 as coupled at the nonreadout side to a light-guide (one 4-to-1 module with a uniform glass light-guid

166 one 4-to-1 module with a uniform glass light-guide, one 4-to-1 Prism-PET module, and one 9-to-1 Prism

167 the environment and use this information to guide ongoing actions.

168 Investigation of these groups will guide ongoing efforts to discover potential risk factor

169 LP was used to guide or confirm procedures.

170 cell walls, not the outer epidermal wall, in guiding organ flattening of organ primordia.

171 ced behavioral performance during a visually guided orientation change detection task, we identified

172 They guide our future actions, form a scaffold for constructi

173 hypotheses to draw reliable conclusions that guide our reasoning and learning.

174 This atlas guides our aetiological understanding by associating SN

175 ay be useful for providing early warning and guiding outbreak response.

176 patial maps in sensorimotor regions known to guide overt and covert spatial selection are influenced

177 for disorders caused by de novo variants can guide patient advocacy groups, clinicians, researchers,

178 n to clinicians could potentially be used to guide patient care.

179 and response to systemic therapy, to safely guide patients through this cautious recovery phase.

180 revascularization was more frequent with FFR-guided PCI (24.9% versus 8.2%; hazard ratio, 3.51 [95% C

181 cerebrovascular events was higher in the FFR-guided PCI versus the CABG group (44.5% versus 31.9%; ha

182 ing with a rationally designed and conserved guiding peptide targets their delivery to chloroplasts.

183 ogy as an adjunct to coronary angiography to guide percutaneous coronary interventions has accumulate

184 patients who underwent real-time ultrasound-guided percutaneous biopsies of space-occupying liver le

185 Ultrasound-guided percutaneous drainage revealed "anchovy sauce" pu

186 n The target median overall survival with CT-guided percutaneous irreversible electroporation was exc

187 uppression can limit unnecessary PPI use and guide personalized management.

188 to rapidly predict SaB patient responses and guide personalized treatment regimens could reduce morta

189 CYP2C19 genotype results along with genotype-guided pharmacotherapy recommendations using a rapid tur

190 oral resolution, and remarkable NIR-II image-guided photothermal therapy.

191 Structure-guided phylogeny of MCP suggests that Yaravirus groups t

192 egant alternative strategy employs small RNA guides, Piwi-interacting RNAs (piRNAs) to identify targe

193 iscuss whether the findings could be used to guide policies aimed at increasing social cohesion and h

194 overstretched, priorities need to be set to guide policy makers, governments, and funding organisati

195 , seroprevalence levels in a population help guide policy surrounding reopening efforts.

196 immunophenotype patients with sepsis and to guide potential new immunotherapies.

197 This Review summarizes the current data guiding preoperative risk stratification as well as peri

198 quently in the chronic phase is presented to guide preventive measures and improve overall cardiometa

199 families with cardiovascular disease and may guide primary intervention strategies based on predicted

200 opological 'phase diagram', which provides a guiding principle for the design of both phase-preservin

201 iplinary study around sanitation to identify guiding principles for sanitation that advance sustainab

202 thrilled to share some of the unconventional guiding principles that brought me to where I am in this

203 Background Prophylactic image-guided procedures performed by interventional radiologis

204 sms associated with cell line phenotypes and guide process optimization, comprehensive omics data ana

205 a parallel rise in the use of biomarkers to guide prognostication and treatment decision-making.

206 of additional transposase proteins, and will guide protein engineering efforts to leverage this syste

207 MRI-guided radiotherapy is a novel and rapidly evolving tech

208 s of the human MTL and how this reactivation guides recall of episodic information.

209 outcomes included agreement to the genotype-guided recommendations.

210 ring techniques could potentially be used to guide resuscitation.

211 ess the protospacer adjacent motif (PAM) and guide RNA (gRNA) requirements of 79 Cas9 proteins, thus

212 nt CRISPR/Cas9 gene editing dogma for single guide RNA (sgRNA) delivery is based on the premise that

213 utation to -124C was achieved using a single guide RNA (sgRNA)-guided and catalytically impaired Camp

214 al muscle myoblast cell lines using a single-guide RNA (sgRNA).

215 mbly, expression and processing of synthetic guide RNA arrays in vivo.

216 do not prevent cleavage in vitro by the Cas9/guide RNA complex.

217 odifications of adenine base editor mRNA and guide RNA expand the applicability of CRISPR-associated

218 iological applications such as the design of guide RNA for CRISPR experiments.

219 g using a ubiquitin regulator-focused single-guide RNA library in HL lines carrying either wild-type

220 igment epithelial cells using a focused dual guide RNA library targeting 852 DDR-associated genes.

221 e of the most prevalent polymorphisms in the guide RNA target site in collections of colonized and wi

222 leotide small interfering RNAs (siRNAs) that guide RNA-directed DNA methylation.

223 lity to join to specific genomic Cas9/single-guide RNA-generated bait DSBs.

224 es, insertions and deletions relative to the guide RNA.

225 contain genetic clones harboring individual guide RNAs (gRNA), we identify RNA-binding proteins (RBP

226 ination (HR), we designed a series of single guide RNAs (sgRNAs) flanking the mutation and provided d

227 9 targeted to the CDKL5 promoter using three guide RNAs causes significant reactivation of the inacti

228 lung cancer, as well as during fluorescence-guided robotic surgery.

229 erging innovations in offline and online MRI-guided RT, exciting opportunities they offer for advanci

230 the molecular mechanism of resistance and to guide second-line therapy.

231 domized controlled telemedicine trial of CBT-guided self-help (CBT-GSH) assisted with a smartphone ap

232 imple behaviors.SIGNIFICANCE STATEMENT Motor-guided sensation and perception are intertwined, with mo

233 Using structure-guided sequence analysis we uncover previously uncharact

234 ing cells in vitro is no exception, with the guided series of differentiation events producing hetero

235 the tendency of participants to under-encode guided sides of the triangles and an influence of past t

236 lar, we emphasize exploratory tools that can guide spatial sampling and highlight the need for greate

237 of the BGC provided structural insights and guided stable-isotope labeling experiments, which led to

238 NSCLC who underwent endobronchial ultrasound-guided staging from a single center were included.

239 ross diverse biological systems where forces guide structure and function.

240 ine reward value with sensory confidence and guide subsequent learning.

241 hematical models that are frequently used to guide such campaigns, human behaviour is often ill-repre

242 ntial to combine both fluorescence for image-guided surgery (IGS) and photodynamic therapy (PDT) to r

243 , there are currently only a small number of guiding synthetic strategies available to generate novel

244 provide holographic 3D guidance to assist CT-guided targeting.

245 This information can be used to guide testing, treatment, and public health prevention e

246 the shape of the substrate nanocrystal must guide the crystallographic orientation of the overgrowth

247 mathematical modeling can help optimize and guide the design of clinical trials.

248 sms of disease pathogenesis, and may help to guide the development of efficacious therapies for MS.

249 ular changes that occur in these tissues may guide the development of more efficacious antidepressant

250 this physiological feature could potentially guide the development of neuromodulation therapies for T

251 isms by which stress regulates attention may guide the development of novel treatments for psychiatri

252 indings help to deepen our understanding and guide the discovery of next-generation water harvesting

253 location of key molecular events, which may guide the evaluation of new therapies.

254 orm is based on understanding the rules that guide the permeation of molecules into bacteria and on a

255 ng this clinical question as a case study to guide the reader through (1) the pros and cons of each a

256 onal analysis, each supervisor initiative to guide the resident was identified, categorized, and anal

257 x, using anatomical scans of each subject to guide the TMS coil, starting at 25% of maximum stimulato

258 al atherosclerotic cardiovascular disease to guide the use of preventive pharmacotherapies, such as a

259 reviews and Meta-Analyses (PRISMA) checklist guided the reporting of the data.

260 that can be read by the spindle, which then guides the axis of cell division.

261 nding of their mechanism of actions but also guides the design and selection of drug candidate molecu

262 CE vial during extraction and simultaneously guides the injection end of a separation capillary into

263 perior olive (LSO) this spontaneous activity guides the strengthening and silencing of synapses which

264 ed to help identify disease-related genes by guiding the development of background-mutation models th

265 sm that links information on gaze direction, guiding the observer's attention to the relevant object,

266 in combination with the geomagnetic field to guide their flight, but how these cues are processed and

267 em cells and that targeted interventions can guide them through their neuronal differentiation.

268 and grasping and the neural principles that guide them.

269 gic cure merits further study as a metric to guide therapeutic interventions for patients with bacter

270 n the ICU, however, there is limited data to guide therapies and targets.

271 609 DLBCL patients participating in the PET-Guided Therapy of Aggressive Non-Hodgkin Lymphomas trial

272 nanoplatform, named TCZ-PNPs, for PA-imaging-guided therapy of RA.

273 zation (cTACE) is a guideline-approved image-guided therapy option for liver cancer using the radiopa

274 Outcome data from procalcitonin-guided therapy trials have shown similar mortality, but

275 many cooperative groups in the study of PET-guided therapy.

276 s anterograde microtubule polymerization and guides these microtubules to subdivide the tip into mult

277 rs after connective tissue grafting (CTG) or guided tissue regeneration (GTR) using bioabsorbable bar

278 Infection control is a major determinant of guided tissue regeneration (GTR).

279 erences in sequencing protocol and provide a guide to downstream analyses and allow for exclusion of

280 n reactions", the polymer serves as a steric guide to limit DNA hybridization in a fixed direction, w

281 s catered for by updates from the IUPHAR/BPS Guide to Pharmacology and the Therapeutic Target Databas

282 As a guide to safe drug development, it therefore becomes imp

283 ess in this endeavour, and provide a general guide to the selection of methods and molecular tools fo

284 prokaryotic Argonaute proteins use small DNA guides to cleave DNA, a process known as DNA interferenc

285 Here we used fMRI-guided transcranial magnetic stimulation (TMS) and simul

286 adding support for pathology-proven data to guide treatment in relevant cases.

287 erlying pathobiological mechanisms that will guide treatment.

288 FDA regulatory approval of modernized AST to guide treatment.

289 onal imaging of the retina is widely used to guide treatment.

290 rs that inform about patient lung status and guide treatment.

291 MYD88 and CXCR4 can be used for a precision-guided treatment approach to WM.

292 esulted in a greater need for susceptibility-guided treatment.

293 yping is now considered an essential step in guiding treatment decision-making in the management of p

294 diagnosis, grading the severity of disease, guiding treatment, detecting complications, and evaluati

295 with pancreatic cancer, and that molecularly guided treatments targeting oncogenic drivers and the DN

296 of MS will require implementation studies to guide use of MS testing, to support diagnosis of MS indu

297 Image-guided VAB alone did not detect surgically confirmed res

298 s as measured by neutralization, which could guide vaccine design.

299 h prefrontal regions of the primate brain to guide value-based decisions.

300 We identify principles that guide whether physical distancing, masks and other barri