ライフサイエンスコーパス: hCG

1 hCG also prevents Neisseria gonorrhoeae from developing

2 hCG also retained dendritic cells in a tolerogenic state

3 hCG assembly appears to be limited by the need to disrup

4 hCG cleavage by gonococcal IgA1 proteases in vivo may in

5 hCG cleaved a few additional proteins, although this occ

6 hCG impact on Treg suppressive capacity was studied in v

7 hCG is heterodimeric and functionally defined by its bet

8 hCG is stabilized by a strand of its beta-subunit that h

9 hCG signaling activates silent mating type information r

10 hCG treatment also decreased cell invasion, which was mo

11 hCG treatment prevented the tumor necrosis factor-depend

12 hCG was cleaved in the beta subunit by the type 1 but no

13 hCG was measured using a solid-phase competitive chemilu

14 hCG, also known as the pregnancy hormone, was detected b

15 hCG-generated Tregs were fully functional and could conf

16 hCG-induced histone methylation is mediated through EZH2

17 hCG-NPM/RAR alpha leukemic cells resembled monoblasts.

18 hCG-PR x PU.1+/- mice developed a typical APL syndrome a

19 capillary glucose [FCG] level, 2-hour CG [2-hCG] level, and glycated hemoglobin A1c [HbA1c] level) a

20 9; FCG level > 7 mmol/L, 4.5% of patients, 2-hCG level > 11 mmol/L, 6.8%; and HbA1c level > 6.5%, 9.3

21 [95% CI, .7-8.7] at follow-up; aOR for the 2-hCG level: 6.6 [95% CI, 4.0-11.1] vs 1.6 [95% CI, .8-2.9

22 In avelumab-resistant patients (46.7%), hCG was normalized with actinomycin D (42.3%) or combina

23 In females having spontaneous abortions, hCG provoked not only an augmentation of Treg numbers, b

24 Administered hCG reduces risk of carcinogen-induced breast cancer in

25 atic reduction of progesterone by 24 h after hCG administration.

26 Samples of r-alpha hCG obtained from a CHO cell line were also analyzed and

27 tryptic glycopeptides and glycans of r-alpha hCG to enable the assignment of glycan structures to ind

28 inant human chorionic gonadotrophin (r-alpha hCG), a protein that is glycosylated at two sites and is

29 Analysis of r-alpha hCG, using capillary electrophoresis (CE) with a separat

30 adotrophin (hCG), and antibodies, anti-alpha-hCG and anti-beta-hCG, using a sandwich assay by surface

31 logical assay that showed that the hCG-alpha-hCG-beta heterodimer facilitated human CG receptor-media

32 urine of pregnant women consistently altered hCG and PPARgamma expression in primary placental cells.

33 ta strongly suggest that PLA(2)G4A amplifies hCG induction of PTGS2 and colocalizes with the induced

34 ntibodies, we use a short oligopeptide as an hCG receptor to bind hCG.

35 ighest possible screening sensitivity for an hCG-based pregnancy test therefore is estimated to be 90

36 ors labeled with gold-deglycosylated hCG, an hCG antagonist, also exhibit restricted lateral diffusio

37 They also recommended measuring AFP and hCG shortly before retroperitoneal lymph node dissection

38 these TM with those in hCG-PML/RAR alpha and hCG-PLZF/RAR alpha TM.

39 Both TNF-alpha antibody and hCG reduced TNF-alpha levels in sera by approximately 75

40 of interaction between anti-hCG antibody and hCG that exhibited 6.5 times higher sensitivity for the

41 Ten patients received chemotherapy, and hCG concentrations returned to normal in eight (80%) of

42 Cleavage of the alarmins by HC and hCG suggests a function in regulating excessive inflamma

43 %) patients continued under surveillance and hCG values spontaneously returned to normal without chem

44 n FSH and AR-induced maturation in vitro and hCG-induced maturation in vivo.

45 ivered the scale of interaction between anti-hCG antibody and hCG that exhibited 6.5 times higher sen

46 For anti-hCG (human chorionic gonadotropin) mAb 8F11, studied at

47 nic gonadotropin (hCG)/mouse monoclonal anti-hCG and goat IgG (anti-intact hCG)/ mouse monoclonal ant

48 Two types of antibody hCG, (beta and alpha, both can specifically bind with hC

49 is was inhibited by treatment with antisense hCG/LH receptor phosphorothioate oligodeoxynucleotide.

50 trophoblast (STB)-specific proteins, such as hCG and GDF15.

51 Similar to LH receptors labeled with Au-hCG, LH receptors labeled with gold-deglycosylated hCG,

52 ing the beta human chorionic gonadotropin (b-hCG) test from both the morphology of an embryo and the

53 g in 6,976 B-human chorionic gonadotropin (B-hCG)-positive specimens, as determined by the Auszyme Mo

54 with disease stage, FIGO score, or baseline hCG.

55 The 5HRE beta-hCG reporter system described here enables serial, nonin

56 3-pentafluoropropyl)acetamide (EF5) and beta-hCG and pimonidazole, two extrinsic markers for tumor hy

57 t syntheses of homogeneous beta-hLH and beta-hCG bearing model glycans at all native glycosylation si

58 blast differentiation proteins GCM1 and beta-hCG, and increased invasion of the extravillous trophobl

59 and antibodies, anti-alpha-hCG and anti-beta-hCG, using a sandwich assay by surface plasmon field-enh

60 tometry indicate colocalization between beta-hCG and 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentaf

61 nes and primary breast tumors expressed beta-hCG, c-Met, beta 1-->4-N-acetylgalactosaminyl-transferas

62 ers: beta-human chorionic gonadotropin (beta-hCG), oncogene receptor (c-Met), beta 1-->4-N-acetylgala

63 ost complex human glycoprotein hormone (beta-hCG) as well as its closely related homologue (beta-hLH)

64 The combination of beta-hCG and MAGE-A3 mRNA markers correlated significantly wi

65 en route to the N-terminal fragment of beta-hCG and the sequential installation of four O-linked gly

66 Secretion of beta-hCG from xenografts that contain these stable constructs

67 ted with this plasmid construct secrete beta-hCG in response to hypoxia or hypoxia-inducible factor 1

68 Structurally, beta-hCG shares a high degree of sequence similarity with bet

69 beta-human chorionic gonadotropin test (beta-hCG < 6 IU/L) 17 days after egg retrieval.

70 e element (HRE) ligated upstream of the beta-hCG gene.

71 We adapted this approach to use urinary beta-hCG as a secreted reporter protein for tumor hypoxia.

72 Similarly, urinary beta-hCG levels decline after treatment with flavopiridol, an

73 We observed no association between hCG and breast cancer risk, overall [Quartile 4 vs. 1, O

74 age, confirming a strong association between hCG and miscarriage.

75 and that a conformational difference between hCG-beta and mCG-beta was recapitulated in the context o

76 hort oligopeptide as an hCG receptor to bind hCG.

77 Both hCG and MMSs will be specifically captured by the fibre

78 d microbeads, simultaneous detection of both hCG and PSA on each gel pad array is achieved with singl

79 d pathology in transgenic mice and that both hCG and antibody to TNF-alpha prevent the development of

80 on of PU.1 for leukemia progression, we bred hCG-PR mice with PU.1+/- mice and assessed their phenoty

81 RTH 43-kDa protein in Leydig cells caused by hCG treatment was prevented by the androgen receptor ant

82 mans, interrupting the inflammatory cycle by hCG opens new perspectives for therapeutic intervention

83 perstimulation of testosterone production by hCG, although basal testosterone levels are maintained d

84 The captured hCG can disrupt a thin layer (~6 mum) of LC covered on t

85 important tumor markers: AFP, ferritin, CEA, hCG-beta, CA 15-3, CA 125, and CA 19-9.

86 quine chorionic gonadotropin (eCG)/human CG (hCG) treatment and mating, ovulation and fertilization r

87 ique structures of human choriogonadotropin (hCG) and related glycoprotein hormones make them well su

88 , teFSH analogs of human choriogonadotropin (hCG) are assembled by a pathway in which the subunits do

89 ty residues of the human choriogonadotropin (hCG) beta-subunit that are wrapped around alpha-subunit

90 he manner in which human choriogonadotropin (hCG) contacts lutropin receptors (LHR) have been stymied

91 cer in animal models, and higher circulating hCG concentrations were associated with significantly lo

92 ired for the formation of assembly-competent hCG subunits and that the invariant Gly residue is requi

93 of the slope ratio of the low concentration hCG protein assay in linear regression analysis was GO-p

94 Like its human counterpart hCG-beta with which it shares 81% identity, macaque (m)C

95 ys, followed by 3 IV doses EPO over 3 days), hCG+Saline using the same schedule, Saline+EPO using the

96 H receptors labeled with gold-deglycosylated hCG, an hCG antagonist, also exhibit restricted lateral

97 We hypothesized that trophoblast-derived hCG modulates the immune population present at the mater

98 -free and label-free mechanism for detecting hCG.

99 o four treatment groups: hCG+EPO (3 IM doses hCG over 5 days, followed by 3 IV doses EPO over 3 days)

100 rnal-embryonic crosstalk, in which embryonic hCG via endometrial PROK1 may play a pivotal role in enh

101 The incorporation of an engineered hCG-SNAP fusion reporter protein (human chorionic gonado

102 Interestingly, in coculture experiments, hCG-treated endometrial cells induce an increase in T ce

103 ed surface by adsorbing monobiotinylated Fab-hCG in place of the whole antibody.

104 tudy, using an extremely sensitive assay for hCG, 10% of clinical pregnancies were undetectable on th

105 the hormone are thought to be essential for hCG activity.

106 tial to become a portable diagnostic kit for hCG.

107 Compared to other detection methods for hCG, this detection method does not require the use of a

108 This differs from hCG assembly, which occurs by threading the glycosylated

109 Staining of oocytes from hCG-stimulated mice with the anti-PT172 antibody also sh

110 ed under the control of a human Cathepsin G (hCG) minigene.

111 nder the direction of the human cathepsin G (hCG) promoter.

112 ymase (HC) and human neutrophil cathepsin G (hCG) show relatively similar cleavage specificities: the

113 rossed PML(-/-) mice with human cathepsin G (hCG)-PMLRARalpha or mammary tumor virus (MMTV)/neu trans

114 treatment with human chorionic gonadatropin (hCG) prevented death and the expression of HIV-1 mRNA an

115 Human chorionic gonadotrophin (hCG) is largely used to confirm pregnancy.

116 ve or until a human chorionic gonadotrophin (hCG) test confirmed pregnancy.

117 a subunits of human chorionic gonadotrophin (hCG), a hormone essential to modulate maternal physiolog

118 n an antigen, human chorionic gonadotrophin (hCG), and antibodies, anti-alpha-hCG and anti-beta-hCG,

119 FP) 2.0 ng/mL, human chorionic gonadotropin (hCG) 151,111 IU/L, and lactate dehydrogenase 588 U/L.

120 In contrast, human chorionic gonadotropin (hCG) and other glycoprotein hormones are secured by a st

121 ancer markers, human chorionic gonadotropin (hCG) and prostate specific antigen (PSA), in serum sampl

122 mone (hLH) and human chorionic gonadotropin (hCG) are human glycoprotein hormones each consisting of

123 Using human chorionic gonadotropin (hCG) as a model analyte to describe the properties of ph

124 nstrated using human chorionic gonadotropin (hCG) as an example.

125 of syncytial [human chorionic gonadotropin (hCG) beta] and fusogenic [syncytin 1, syncytin 2, and gl

126 Serum human chorionic gonadotropin (hCG) concentration was 200 mIU/ml; she was hemoconcentra

127 include raised human chorionic gonadotropin (hCG) concentrations 6 months after uterine evacuation of

128 gnancy hormone human chorionic gonadotropin (hCG) efficiently attracts human Tregs to trophoblasts, f

129 Human chorionic gonadotropin (hCG) induces de novo synthesis of STAR, a process shown

130 that human embryonic chorionic gonadotropin (hCG) induces sequential mRNA expression of PROK1 and LIF

131 e that secrete human chorionic gonadotropin (hCG) into the host mouse and include small areas of trop

132 Human chorionic gonadotropin (hCG) is a glycoprotein hormone essential to pregnancy.

133 Human chorionic gonadotropin (hCG) is a glycoprotein secreted during pregnancy that ha

134 Human chorionic gonadotropin (hCG) is a heterodimeric member of a family of cystine kn

135 Human chorionic gonadotropin (hCG) is an important biomarker for the diagnosis of preg

136 Human chorionic gonadotropin (hCG) is necessary for the maintenance of early pregnancy

137 Human chorionic gonadotropin (hCG) is one of the earliest hormones produced by the bla

138 a single serum human chorionic gonadotropin (hCG) level that is diagnostic of ectopic pregnancy.

139 2 weeks until human chorionic gonadotropin (hCG) normalization, followed by 3 consolidation cycles.

140 The impact of human chorionic gonadotropin (hCG) on prostate carcinoma viability was investigated.

141 Human chorionic gonadotropin (hCG) promotes proliferation of endogenous neural stem ce

142 pecificity for human chorionic gonadotropin (hCG) protein.

143 The human chorionic gonadotropin (hCG) proteins constitute a diverse group of molecules th

144 t of mice with human chorionic gonadotropin (hCG) resulted in increased circulating testosterone leve

145 The hormone human chorionic gonadotropin (hCG) serves to maintain the fetus during early pregnancy

146 We detect human chorionic gonadotropin (hCG) using an antibody-based sandwich assay and quantita

147 stimulated by human chorionic gonadotropin (hCG) via cyclic AMP-induced androgen formation in testic

148 e present work human chorionic gonadotropin (hCG) was used as a model protein in a proof-of-concept s

149 indicate that human chorionic gonadotropin (hCG), a hormone that is present in very high levels duri

150 s suggest that human chorionic gonadotropin (hCG), a major hormone of pregnancy, could play a role in

151 tein (CRP) and human chorionic gonadotropin (hCG), by using fluorescent-labeled polyclonal antibodies

152 n pregnancy hormone, chorionic gonadotropin (hCG), in the liver.

153 iator molecule human chorionic gonadotropin (hCG), we interface the intracellular information to enzy

154 V derived from human chorionic gonadotropin (hCG)-beta.

155 er exposure to human chorionic gonadotropin (hCG).

156 mplantation is human chorionic gonadotropin (hCG).

157 nhancing drug, human chorionic gonadotropin (hCG).

158 ent binding of Human Chorionic Gonadotropin (hCG).

159 s were investigated: chorionic gonadotropin (hCG)/mouse monoclonal anti-hCG and goat IgG (anti-intact

160 eta-subunit of human chorionic gonadotropin (hCG-beta).

161 protein [AFP], human chorionic gonadotropin [hCG], and lactate dehydrogenase [LDH]) before and after

162 were randomized into four treatment groups: hCG+EPO (3 IM doses hCG over 5 days, followed by 3 IV do

163 Eight patients (53.3%) had hCG normalization after a median of 9 avelumab cycles; n

164 b resistance were investigated using a Hep3B-hCG orthotopic human xenograft model of locally advanced

165 pital, London, UK, who had persistently high hCG concentrations 6 months after evacuation of hydatidi

166 ith hydatidiform moles had persistently high hCG concentrations of more than 5 IU/L 6 months after ev

167 nce policy would be clinically acceptable if hCG values returned to normal in 75% of patients or more

168 ance of disease was 84%, compared with 7% in hCG-PR x PU.1+/+ mice (P < 0.0001).

169 The residual PU.1 allele in hCG-PR x PU.1+/- APL cells was expressed, and complete e

170 tributions that noncysteine residues make in hCG folding, secretion, and assembly.

171 leukemia observed in these TM with those in hCG-PML/RAR alpha and hCG-PLZF/RAR alpha TM.

172 breast cancer risk decreased with increasing hCG (upper tertile OR, 0.67; CI, 0.46-0.99), especially

173 onoclonal anti-hCG and goat IgG (anti-intact hCG)/ mouse monoclonal anti-goat IgG.

174 face was determined by covalent 125I-labeled hCG crosslinking to intact, stably transfected mammalian

175 sence of functional luteinizing hormone (LH)/hCG receptors in human breast cells, prompted us to inve

176 ing hormone/human chorionic gonadotropin (LH/hCG) receptor (LHR) in cultured hypothalamic cells and i

177 vide novel insights into the mechanism of LH/hCG receptor activation.

178 gically active heterodimer, mCG, which, like hCG, is required for pregnancy maintenance.

179 The longitudinal submodel for log hCG included a random intercept and slope and fixed line

180 Unit increases in log hCG corresponded to a 63.9% (HR 0.36, 95% CI 0.16, 0.47)

181 Yet evidence shows that longitudinal hCG profiles are distinguishable between healthy and fai

182 However, they recommended measuring hCG and AFP to monitor for relapse in patients treated f

183 chemotherapy groups, apart from lower median hCG concentrations 6 months after evacuation in those un

184 terodimer assembly and is thought to mediate hCG-LHR interactions.

185 With the assistance of microfluidics, hCG sample was delivered via single-injection to 3-Amino

186 dent protein kinase, dibutyryl cAMP mimicked hCG in preventing NF-kappaB activation, and dideoxyadeno

187 emale mice were treated either with 10 IU/ml hCG or PBS at days 0, 2, 4, and 6 of pregnancy.

188 Moreover, hCG stimulates FasL mRNA and protein expression without

189 This explains why most hCG is assembled by threading the glycosylated end of al

190 7 were of macaque origin (PGVD), the mutated hCG-beta subunit displayed macaque-like conformational r

191 e compartments despite treatment with 100 nm hCG as do LH receptors on cells treated with cytochalasi

192 s, LH receptors on cells treated with 100 nm hCG exhibit restricted lateral diffusion and are confine

193 ompartments on KGN cells treated with 100 nm hCG.

194 Young, nonleukemic hCG-PR x PU.1+/- mice developed splenomegaly because of

195 lation of syncytin 1 and syncytin 2, but not hCG beta, in primary human cytotrophoblasts.

196 inding and signal transduction activities of hCG analogs in which the alpha-subunit C terminus (alpha

197 carboxyl terminus had 10-20% the activity of hCG.

198 Application of hCG increased Treg frequency in vivo and their suppressi

199 her, our results demonstrate that binding of hCG induces aggregation of LH receptors within nanoscale

200 sequently in the SAM, to maximize binding of hCG of the streptavidin-bound antibody.

201 ce and treated in vitro with combinations of hCG, DHT, and BMP4 inhibitors.

202 Depending on the initial concentration of hCG, LC gives distinct optical signals visible to the na

203 nts with low and declining concentrations of hCG 6 months after evacuation of hydatidiform mole.

204 Long-term stability (45 days) of hCG in dried spots at reduced temperatures (</=8 degrees

205 he results indicated complete dissolution of hCG from the spots, acceptable limit of detection (LOD)

206 hibition attenuated the induction effects of hCG and DHT on estrogen and progesterone secretion in CM

207 i-proliferative and anti-invasive effects of hCG in human breast cancer MCF-7 cells by down-regulatin

208 The cytotoxic effects of hCG were enhanced by expression of dominant-negative Ika

209 lation and enhanced the cytotoxic effects of hCG.

210 PFF increased the mRNA and protein levels of hCG beta, syncytin 1, syncytin 2, and GCM1; and knockdow

211 ptavidin-antibody layer showed that a LOD of hCG of 2 mIU mL(-1) (4 x 10(-12) mol L(-1)) could be rea

212 aline and urine samples, and only 0.6 muL of hCG solution is required.

213 This means that as little as 45.5 pg of hCG can be detected by this method.

214 ive state of the receptor in the presence of hCG, the possibility that S431 promotes receptor activat

215 PFF acts via NPFFR2 to enhance production of hCG beta and promote GCM1-dependent expression of syncyt

216 Considering the low toxicity profile of hCG in humans, interrupting the inflammatory cycle by hC

217 The promotion of hCG lethality by lovastatin was abolished by overexpress

218 uppressed the radiosensitizing properties of hCG.

219 Rate of hCG normalization was the primary endpoint (2-step Simon

220 Rates of hCG normalisation, relapse, and death were assessed in p

221 When the X(1), X(2), and X(3) residues of hCG-alpha and -beta were substituted by swapping their r

222 In addition, the role of hCG as a tumor marker in a variety of cancers has also a

223 This study examined the sensitivity of hCG to gonococcal IgA1 proteases, by means of autoradiog

224 lation differences, we generated a series of hCG-beta-mCG-beta chimeras and identified domains that c

225 During studies of hCG assembly in mammalian cells, we found that addition

226 loop 2 "like a seatbelt." During studies of hCG synthesis in COS-7 cells, we found that, when the se

227 Part of the beta subunit of hCG has an amino acid sequence similar to that of the hi

228 had similar lutropin activities to those of hCG; that in which it was latched to residue 92 at the c

229 nd qualitative differentiation between other hCG variants in a selective, sensitive, and reproducible

230 lar basis, with occasional detection of 1 pg hCG.

231 tographic assays, a detection limit of 10 pg hCG in a 100-microl sample has been achieved on a regula

232 stence of a cross talk between the placenta (hCG) and the decidua (CXCL10) in the control of immune c

233 Our results position hCG in a novel, so far unknown role as modulator of immu

234 mutant mouse ovaries collected at 11 h post-hCG unveiled numerous CBFs-downstream genes that are ass

235 Panel recommended measuring postorchiectomy hCG and LDH for patients with seminoma and preorchiectom

236 ggest that the association between pregnancy hCG and subsequent maternal risk of breast cancer is mod

237 this study, we investigated early-pregnancy hCG concentrations and subsequent breast cancer risk.

238 reatment of MCF-7 cells with highly purified hCG resulted in a modest dose-dependent and hormone-spec

239 vation in the presence of activated LH/CG R, hCG-stimulated ARF6 activation is reduced to basal level

240 nd protein levels for four forms of secreted hCG were measured in the conditioned media.

241 s not detected by X-ray analysis of secreted hCG-beta.

242 e relationship between early pregnancy serum hCG concentrations and breast cancer risk.

243 transvaginal sonogram and quantitative serum hCG testing.

244 Repeat serum hCG levels after chemotherapy were 12.3 IU/L at 2 weeks

245 The serum hCG level was 8.1 IU/L, and there were residual lesions

246 Similarly, hCG-PLZF/RAR alpha TM displayed a different phenotype wh

247 In round spermatids, hCG caused a significant decrease of 61 kDa species and

248 e human chorionic gonadotropin beta-subunit (hCG-beta) reveals the presence of a disulfide between Cy

249 ed by the high compatibility with the target hCG protein, the major advantage of GO-peptide-based SPR

250 le, cell surface membrane compartments, that hCG binding also affects the lateral motions of antagoni

251 In summary, our results demonstrate that hCG has anti-proliferative and anti-invasive effects in

252 ls from decidual samples we demonstrate that hCG inhibits CXCL10 expression by inducing H3K27me3 hist

253 tructs targeted to PROK1 to demonstrate that hCG-mediated LIF expression in the endometrium is depend

254 The findings that hCG treatment increased cAMP synthesis and activated cAM

255 We hypothesized that hCG may be a placental link for the development of local

256 In this study, we hypothesized that hCG not only acts as a chemoattractant of Tregs but also

257 These findings support the premise that hCG could be responsible for the pregnancy-induced prote

258 Here, we report that hCG regulates the SIRT1/FOXO3a axis in hepatocytes, resu

259 We report that hCG treatment decreases cell proliferation and increases

260 These results suggest that hCG may be a link in the development of peritrophoblasti

261 The hCG effect on Treg frequency and cytokine secretion was

262 TAT-CRAC did not affect the hCG-induced cAMP synthesis and the 22R-hydroxycholestero

263 Each mouse carried the hCG-PML/RARA transgene, a well-characterized initiator o

264 In the hCG-dependent steroidogenic MA-10 mouse Leydig cell line

265 type contrasts with what was observed in the hCG-PML/RAR alpha TM model in which the leukemic phase w

266 o bind [(3)H]promegestone and to inhibit the hCG-stimulated steroidogenesis.

267 ed into MA-10 Leydig cells and inhibited the hCG- and cAMP-stimulated steroid production in a dose-de

268 2) terminus, cystine knot, and loop 2 of the hCG beta-subunit.

269 e contributions that cystine residues of the hCG subunit cystine knots make in folding, assembly, and

270 rom one man having received injection of the hCG-containing pharmaceutical Pregnyl were analyzed.

271 ng inconsistent with our earlier view of the hCG-LHR complex.

272 n adenylate cyclase inhibitor, prevented the hCG effect on NF-kappaB suggested that the hCG actions a

273 order of magnitude more effectively than the hCG-alpha-mCG-beta chimera.

274 e hCG effect on NF-kappaB suggested that the hCG actions are mediated via the cAMP-dependent protein

275 Pairwise testing of groups found that the hCG+EPO group had significantly better behavior at 6/10

276 sing a biological assay that showed that the hCG-alpha-hCG-beta heterodimer facilitated human CG rece

277 lity, in terms of its ability to bind to the hCG antigen, was studied.

278 a threading mechanism, as observed when the hCG seatbelt was replaced with its salmon FSH counterpar

279 clude that all three "X" residues within the hCG cystine knots are collectively, but not individually

280 These hCG actions were abrogated when receptor synthesis was i

281 Thus, hCG, in combination with radiation and lovastatin, may r

282 secondary fluorescently labeled antibody to hCG immobilized on the optimized SAM-streptavidin-antibo

283 Exposure of LNCaP cells to hCG promoted activation of epidermal growth factor recep

284 hese cells also express Cyp17 and respond to hCG stimulation but do not express the Leydig specific m

285 ing, and its levels increased in response to hCG treatment.

286 or to mediate cAMP production in response to hCG, suggesting that S431 stabilizes the active state of

287 main, the site phosphorylated in response to hCG.

288 xpressing mutant receptor were responsive to hCG with respect to production of inositol phosphates.

289 guanine-DNA alkyltransferase) led to LAMP-to-hCG signal transduction on low-cost, commercially availa

290 Total hCG was determined on Immulite 2000 analyzer.

291 g early pregnancy outcomes based on updating hCG measurements.

292 tion between longitudinally measured urinary hCG and early miscarriage.

293 In vivo, we investigated whether hCG enhances Treg suppressive capacity indirectly by mod

294 a and alpha, both can specifically bind with hCG), were adhered on the surface of fibre sensor and MM

295 Treatment of cells with hCG followed by exposure to ionizing radiation enhanced

296 Treatment of LNCaP and PC-3 cells with hCG modestly reduced cell viability within 96 h.

297 eted, and its ability to heterodimerize with hCG-beta.

298 Treatment with hCG and lovastatin decreased expression of BCL-(XL) and

299 togram analysis indicate that treatment with hCG induces aggregation of YFP-coupled LH receptors stab

300 Treatment with hCG+EPO significantly reduced total lesion volume by 82-