ライフサイエンスコーパス: habituation

1 and decreases in the absence of such risks (habituation).

2 cy of items estimated over a long timescale (habituation).

3 ation, highlighting the multifactoriality of habituation.

4 iar stimuli, thereby resulting in behavioral habituation.

5 at BK channels might play a critical role in habituation.

6 onditioned mice and improved olfactory cross habituation.

7 findings for potential treatments enhancing habituation.

8 agonism or DRN activation with ChR2 reduces habituation.

9 uromuscular junction, and impaired olfactory habituation.

10 usceptibility and decreased acoustic startle habituation.

11 c predisposition and a deficit in short-term habituation.

12 ability to engage the mechanism of emotional habituation.

13 These mice show deficits in short-term habituation.

14 avoidant patients in neural activity during habituation.

15 ior cingulate functional connectivity during habituation.

16 elopment and instead acts acutely to promote habituation.

17 alterations of PPI, startle reactivity, and habituation.

18 ish was shown the same stimuli as during the habituation.

19 artle attenuates with the characteristics of habituation.

20 ry and gustatory learning behavior and touch habituation.

21 ical prediction rather than passive synaptic habituation.

22 se resultant plasticity underlies behavioral habituation.

23 oral attenuation characteristic of olfactory habituation.

24 tory system to derive a simple algorithm for habituation.

25 t contextual cues regulate HPA axis response habituation.

26 a time course similar to that of behavioral habituation.

27 mination, synapse maintenance and behavioral habituation.

28 regulation within alpha'beta'neurons impairs habituation.

29 and we tested these models in light-off jump habituation.

30 ed within these neurons to prevent premature habituation.

31 onds mostly contributed to the modulation of habituation.

32 f BK channels in vivo can enhance short-term habituation.

33 g decreases in spontaneous firing and neural habituation.

34 ecial type of adaptive memory referred to as habituation.

35 cal or perceptual cues can limit or increase habituation.

36 uted to a lesser extent to the modulation of habituation.

37 Amygdala reactivity, but not habituation, 5 to 12 weeks after trauma was positively a

38 ess-related responses associated with stress habituation, a process that is inadequately understood.

39 a decrease in its subsequent intake through habituation--a decrease in one's responsiveness to the f

40 vity co-segregates with extent of behavioral habituation across generations.

41 iform gyrus that was subject to intersession habituation across groups without showing significant se

42 Rs of the indirect pathway are essential for habituation, action selection, and goal-directed learnin

43 oustic startle response, startle reactivity, habituation, ADHD symptoms, and cocaine craving were ass

44 of the odor cue itself, followed by response habituation after processing of a matching (vs nonmatchi

45 Habituation also represents a filter for inundating sens

46 patterns of behavior and a relative lack of habituation among patients with bipolar disorders compar

47 tantly, both Oga lines exhibited deficits in habituation, an evolutionarily conserved form of learnin

48 ecreases during habituation in proportion to habituation and a genetic manipulation that reduces sero

49 Impaired habituation and accentuated sensitization in response to

50 o distinct forms of learning: nonassociative habituation and associative learning by pairing with a s

51 of the protein in the MBs yielded premature habituation and depressed PSD-LTM.

52 ion in infants and young children, including habituation and dishabituation, imitation-based tasks, a

53 autonomic cross-adaptive effect between cold habituation and exposure to acute hypoxia in humans.

54 aily presentation of food resulted in faster habituation and less energy intake than did once-weekly

55 it could have been caused by factors such as habituation and not by supportive context.

56 t CRFOE during development decreased startle habituation and prepulse inhibition, and increased avoid

57 od over daily meals can increase the rate of habituation and reduce energy intake.

58 Larval herbivores employ habituation and sensitization-strategies useful in their

59 ed habituation occludes further odor-induced habituation and similarly requires GABA(A)Rs and NMDARs

60 hanism can be targeted to enhance short-term habituation and therefore to potentially ameliorate sens

61 c perspective on the biological mechanism of habituation and use this perspective to understand how s

62 Output from PNs is necessary for olfactory habituation and, in the absence of odorant, direct PN ac

63 Less neural habituation (and significant sensitization) in the fragi

64 ory (deferred imitation, relational binding, habituation) and attention tasks (visual expectation, au

65 r of perovskites that naturally incorporates habituation, and demonstrate learning to forget: a key f

66 from sensitization in that it is preceded by habituation, and is thus a paradigm for metaplasticity.

67 s an emerging role for inhibitory neurons in habituation, and reveals an opposing, circuit-level-base

68 cterized as reflecting change detection than habituation, and that their apparent selectivity to spee

69 g to synaptic depression that is crucial for habituation, and we discuss the significance of our find

70 translation, long-term memory, and footshock habituation are also revealed.

71 h as reliability, plasticity, and adaptation/habituation are altered in autism.

72 rved within a meal such that faster rates of habituation are associated with less energy intake.

73 olecular level, ID genes required for normal habituation are enriched in synaptic function and conver

74 hese two temporally distinguishable forms of habituation are mediated by different cellular mechanism

75 This habituation arises locally in A1 and involves an enhance

76 These findings establish habituation as a possible, widely applicable functional

77 e processes we developed and characterized a habituation assay to repetitive footshocks in mixed sex

78 e olfactory system, the neural correlates of habituation at a fast experimental timescale involving v

79 Here, we report the discovery of habituation-based plasticity utilizing a perovskite quan

80 re were no significant differences regarding habituation between medication exposure groups.

81 These mutants have normal olfactory habituation, but exhibit a striking array of locomotor p

82 Furthermore, we found little evidence for habituation by murres to the UAV.

83 s in larger groups may function similarly to habituation, causing them to spend more time shoaling th

84 In its simplest form, long-term habituation could result from a plasticity event at a si

85 hizophrenia in humans, also characterized by habituation defects and ameliorated by these pharmaceuti

86 o replicate the previously reported amygdala habituation deficit in BPD and probed this neural phenot

87 asping abnormality of their hind limbs and a habituation deficit.

88 euronal substrates underlying the identified habituation deficits and integrated genotype-phenotype a

89 that, like for Hip14, loss of Kv1.1 leads to habituation deficits and that Hip14 is dispensable in de

90 r lines this phenotype results from apparent habituation deficits.

91 molecular processes that are associated with habituation deficits.

92 anges in BG output, which is seen as reduced habituation, delay in goal-directed learning, lack of as

93 nstream effectors in pappaa mutants restores habituation, demonstrating that pappaa promotes learning

94 Thus, habituation designs that include various items may be as

95 The assay provides a sensitive readout of habituation, discrimination and exploration, as well as

96 ic distinctiveness of sound elements using a habituation-discrimination paradigm on wild-caught babbl

97 We use a simple habituation-dishabituation paradigm in which animals mus

98 e and contextual fear conditioning, and odor habituation-dishabituation.

99 Here we combine a habituation/dishabituation behavioural task with molecul

100 Based on a habituation/dishabituation paradigm, we show that, after

101 to discriminate social odors on an olfactory habituation/dishabituation task.

102 induces stress, the scale of this stress and habituation dynamics remain unclear.

103 d that memantine treatment normalized the P2 habituation effect at the follow-up visit.

104 tity priming can counter-act classic sensory habituation effects, allowing identity-relevant smells t

105 or punishment, manifested through behavioral habituation, enables organisms to detect novelty and dev

106 viorally, burst-dependent protection reduces habituation, enabling animals to maintain responsiveness

107 th a pattern suggestive of impaired amygdala habituation even when controlling for depressive and anx

108 Moreover, habituation failure upon dBtk abrogation in neurons wher

109 Habituation has been studied in different organisms and

110 A more extended form (termed "short-term habituation" here), which persisted for >/=25 min but <1

111 ts showed odorants differed significantly in habituation, highlighting the multifactoriality of habit

112 rocessing: arousal (i.e., initial response), habituation (i.e., change in response over time), and ge

113 rrent study was designed to assess long-term habituation in 16 obese and 16 nonobese premenopausal wo

114 n increased locomotor activity and decreased habituation in a hippocampal-dependent task.

115 xamining behavioral and neural correlates of habituation in borderline patients, healthy comparison s

116 plicate a prior report on deficient amygdala habituation in BPD and link this neural phenotype to ear

117 Indeed, studies of short-term habituation in C. elegans indicate that in this paradigm

118 s, a critical period for long-term olfactory habituation in Drosophila, which closes early in adultho

119 f the genes and neurons underlying olfactory habituation in Drosophila.

120 Left fusiform habituation in female participants was directly correlat

121 contrast, repeated restraint stress produced habituation in HPA responses, maintained levels of activ

122 elicit protein synthesis-dependent long-term habituation in larval zebrafish, lasting up to 24 h.

123 indings of comparable deficits in short-term habituation in mice lacking the NMDAR receptor subunit G

124 lso help toward understanding the effects of habituation in other more sophisticated neural systems.

125 protease-inactive version of pappaa restores habituation in pappaa mutants.

126 DRN neuron activity decreases during habituation in proportion to habituation and a genetic m

127 s and, unlike healthy subjects, did not show habituation in ratings of the emotional intensity of the

128 tic depression presumably underlying startle habituation in rats, using patch-clamp recordings and vo

129 with ASD showed reduced ability to maintain habituation in the amygdala and relevant sensory cortice

130 Habituation in the ventral anterior cingulate cortex was

131 sham group expressed the expected decrease (habituation) in total distance walked, and distance walk

132 Habituation is a basic form of implicit learning and rep

133 These results indicate that sensory habituation is a dynamic, time-varying process dependent

134 Habituation is a filter that optimizes the processing of

135 Habituation is a form of learning in which repeated expo

136 Habituation is a form of non-associative learning that e

137 Habituation is a form of simple memory that suppresses n

138 mputing in a sequential, dynamic environment.Habituation is a learning mechanism that enables control

139 mples indicate that, relative to reactivity, habituation is a more reliable biomarker of individual d

140 Habituation is a simple form of learning where animals l

141 Habituation is a simple form of memory, yet its neurobio

142 Habituation is an adaptive learning process that enables

143 In Aplysia, habituation is mediated by rapid depression of sensory s

144 Although habituation is one of the most ancient and fundamental f

145 ion of the same food stimulus in a meal, and habituation is reliably observed within a meal such that

146 Habituation is the adaptive behavioral outcome of proces

147 disorders.SIGNIFICANCE STATEMENT Short-term habituation is the most fundamental form of implicit lea

148 Habituation is thought to occur via at least two tempora

149 This behavior, known as habituation, is universal among all forms of life with a

150 hology, locomotion, tactile sensitivity, and habituation learning in 135 strains each carrying a muta

151 lts define the first functional gene set for habituation learning in a vertebrate and identify PAPPAA

152 haviors, the molecular and cellular basis of habituation learning is not well understood.

153 Our work supports the relevance of habituation learning to ASD, identifies an unprecedented

154 For 93 of these genes, a role in habituation learning was previously unknown.

155 GF signaling as a novel mechanism regulating habituation learning.

156 rotein 14 (Hip14) as a critical regulator of habituation learning.

157 echanosensory hyperresponsivity and impaired habituation learning.

158 We identified >100 genes required for habituation learning.

159 The results evidenced a habituation-like hemodynamic response during encoding in

160 Through an analysis of long-term olfactory habituation (LTH) in female Drosophila, we provide new i

161 n Drosophila, short-term (STH) and long-term habituation (LTH) of olfactory avoidance behavior are be

162 (dFMR1) is required for long-term olfactory habituation (LTH), a phenomenon dependent on Atx2-depend

163 ferences were found in startle reactivity or habituation measures.

164 Saccade-contingent habituation might explain why we do not perceive trans-s

165 encing, that identified 14 zebrafish startle habituation mutants including mutants of the vertebrate-

166 cing and Disruptive nights, with a preceding Habituation night (night 1) and an intervening Sham nigh

167 Following a habituation night, subjects lived in a whole-room indire

168 iples involved in the fundamental process of habituation, notably trigeminality and the physicochemic

169 PN-induced habituation occludes further odor-induced habituation an

170 We show here that habituation occurs in response to feedback from PNs.

171 mic response modeling the hypothesis that no habituation occurs.

172 Habituation of a behavioral response to a repetitive sti

173 that neonics affect population responses and habituation of a visual motion detection system.

174 nt (385A allele; rs324420) exhibited quicker habituation of amygdala reactivity to threat, and had lo

175 RF), an enduring trait influenced by chronic habituation of PA that takes place over months or years.

176 le roles of acupuncture and aversiveness and habituation of painful electrical stimulation in mediati

177 tected accurately to determine strategy; and habituation of response to tap, where the response is st

178 te extensive research in the past decades on habituation of startle and other escape responses, the u

179 in synaptic depression underlying short-term habituation of startle.

180 In the rat, habituation of such inhibition can be facilitated via ne

181 r the autism spectrum group, lower levels of habituation of the amygdala to the face stimuli were ass

182 In the current study we demonstrate that habituation of the auditory startle reflex (hASR) tested

183 Here, we describe two forms of short-lived habituation of the C-start in response to brief pulses o

184 Allostatic habituation of the HPA axis, such that glucocorticoid le

185 get were heard, consistent with a process of habituation of the N100 in the auditory cortex due to th

186 = 0.001) without affecting the magnitude or habituation of the startle response (all p > 0.13).

187 t contributes to individuality in short-term habituation of the zebrafish (Danio Rerio) acoustic star

188 e rising pathogen risk created by increasing habituation of wild apes for tourism, and the growth of

189 Habituation of wild great apes for tourism and research

190 augmented, while repeated exposure to (i.e., habituation of) an aversive sound (klaxon-horn) reduced

191 ions, and detachment, which is distinct from habituation or conditioning.

192 is consistent with a modular model in which habituation originates from multiple independent process

193 Orientation-selective habituation (OSH) can be observed both in exploratory be

194 genetic screen to identify olfactory startle habituation (OSH) mutants.

195 one, reflexes, and motor skills and a visual habituation paradigm using a neutral female face.

196 urons, is essential for normal learning in a habituation paradigm.

197 s have been traditionally investigated using habituation paradigms, assuming that babies' memories in

198 ses to emotional stress in sensitization and habituation paradigms.

199 bsence of significant freezing during a 2-wk habituation period and during intertrial intervals indic

200 ver intervention study, consisting of a 20-d habituation period to a protein intake at the RDA or a h

201 Separate groups of zebrafish underwent a habituation phase with a set of 3 or 9 small red dots, a

202 identifies an unprecedented number of novel habituation players, supports an emerging role for inhib

203 d measures of acoustic startle magnitude and habituation, PPI, MMN, autonomic indices, and subjective

204 During olfactory habituation, prior exposure to an odorant selectively de

205 A failure to effectively engage emotional habituation processes may contribute to affective instab

206 done may weaken the "immunity" of disgust to habituation, putatively by reducing gastric dysrhythmias

207 pregnancy was associated with less efficient habituation (r(245)=0.16; P.02).

208 All noise exposed groups displayed similar habituation rates and retention levels.

209 Cold habituation reduced the sympathetic response (indicated

210 failure to habituate.SIGNIFICANCE STATEMENT Habituation refers to processes underlying decisions to

211 es coordination of these responses and their habituation-related declines is not well understood.

212 Habituation represents a fundamental form of learning, y

213 the behavioral and neuronal effects of odor habituation require functioning N-methyl-d-aspartic acid

214 ic neurons specifically inhibit the adaptive habituation response.

215 .g., susceptibility to handling, adaptation, habituation, sensitization), discrimination ability, and

216 wborns participated in visual preference and habituation studies.

217 e same food over days will lead to long-term habituation, such that subjects habituate to foods repea

218 sed to assess brain activation during a gaze habituation task.

219 decrease in infant fixation during a visual habituation task; and mean time looking at the stimulus

220 ermore, these results present the odor cross-habituation test as a powerful behavioral assay, which r

221 o overcome this, the social interaction (SI) habituation test was developed in this lab to systematic

222 nd memory in fear conditioning and olfactory habituation tests.

223 oustic stimulation induces robust short-term habituation that can be modulated by stimulation frequen

224 a byproduct of algal tending and the mutual habituation that damselfish and mysids exhibit towards o

225 ions, such as cognitive behavioural therapy, habituation therapy and acupuncture.

226 context was modified on a test day following habituation, this effect could be mostly attributed to t

227 discern no significant impact of learning or habituation through the analysis of blocked trials, and

228 We demonstrated that habituation to a food item can occur even when its consu

229 Behaviorally, deficits in habituation to a novel environment and semantic-like mem

230 ial exploration and disruption in subsequent habituation to a novel environment, together with height

231 ABA(A) receptors, however, was essential for habituation to a novel environment.

232 e examine whether this contrast is driven by habituation to a repeating condition or by selective res

233 hat mental representation alone can engender habituation to a stimulus.

234 Habituation to an environment can also alter the proport

235 abituation to non-socially derived odors and habituation to an open-field, indicating that the observ

236 g-induced Arc expression, (2) interfere with habituation to auditory stimuli, and (3) alter dendritic

237 on paradigm, we measured White participants' habituation to blocks of White and Black faces that para

238 rs is affected and explore the potential for habituation to boat noise in busy areas.

239 Because of potential habituation to broadcasted calls and social behavior, we

240 There was no evidence for differential habituation to direct gaze compared with averted gaze wi

241 o distinct stressors, rPH muscimol disrupted habituation to each stressor modality, suggesting a nove

242 revious studies have evaluated the impact of habituation to either low protein intake (LOW PRO) or hi

243 After a 2-week period of habituation to ethanol in two-bottle choice, alcohol-pre

244 authors sought to investigate neural system habituation to face and eye gaze in fragile X syndrome,

245 Reactivity (fearful > neutral) and habituation to fearful faces was examined.

246 However, no research on long-term habituation to food in humans has been conducted.

247 ults provide the first evidence of long-term habituation to food in women and show that memory of foo

248 Three weeks of habituation to high protein intake (>2.1 g protein . kg

249 ndial amino acid removal were observed after habituation to high protein, yielding higher urea excret

250 was 0.13 +/- 0.06%/h lower (P < 0.05) after habituation to high protein.

251 be established through a saccade-contingent habituation to intra-saccadic displacements.

252 Habituation to LOW PRO (0.7 g . d(-1)) compared with HIG

253 ging was used to examine brain responses and habituation to mildly aversive auditory and tactile stim

254 RAG1-deficient mice show normal habituation to non-socially derived odors and habituatio

255 mpulsivity, behavioral rigidity, and reduced habituation to novel stimuli.

256 not likely a result of a general deficit in habituation to novelty.

257 In contrast, behavioral habituation to odorants on a longer timescale with inter

258 We here show that behavioral habituation to odorants on this longer timescale has a n

259 on in neural circuits may similarly underlie habituation to other complex stimuli.

260 ercise animals showed quicker glucocorticoid habituation to repeated audiogenic stress.

261 hypothalamic-pituitary-adrenal axis response habituation to repeated loud noise exposures is not deri

262 was first established that HPA axis response habituation to repeated loud noise lasted for at least 4

263 here functional inactivation disrupts stress habituation to repeated loud noise.

264 confirm a significant reduction in amygdala habituation to repeated negative stimuli in BPD (p(FWE)

265 Behavioral, neural, and endocrine habituation to repeated restraint stress and subsequent

266 Female rats exhibited impaired habituation to repeated restraint with subsequent defici

267 a, although work with rodents indicates that habituation to repeated short cold exposures has a cross

268 linked hyperactivation to deficient amygdala habituation to repeated stimuli, but the biological unde

269 oid inhibition of both Arc induction and its habituation to repeated stimuli, combined with preventio

270 not increase physical activity) on HPA axis habituation to repeated stress and modulation of brain n

271 of acute neuroendocrine responses and their habituation to repeated stress.

272 8)F]FECNT binding correlated negatively with habituation to repeated tactile stimulation and positive

273 We demonstrate that habituation to repetitive footshock involves two phases

274 ehavioral improvement reflects a decrease of habituation to somatosensation.

275 ASDs with SOR subgroup had decreased neural habituation to stimuli in sensory cortices and the amygd

276 Significance statement: Habituation to stress is a process that possibly diminis

277 ate that the complementary process of timely habituation to the repetitive stimulation is facilitated

278 TP) that parallel behavioral responses, with habituation to the same acute restraint stressor and sen

279 n of two factors: higher light intensity and habituation to the testing chamber.

280 splayed significantly greater right amygdala habituation to threat-related facial expressions, a phen

281 was used to examine these patterns of neural habituation to two sets of similar mildly aversive audit

282 cribe in mice a form of long-term behavioral habituation to visual grating stimuli that is selective

283 (nicotine(PM), 30 mug/kg, i.v.) resulted in habituation (tolerance) of the same physiological, neuro

284 ASR habituation varies greatly between individuals, but diff

285 Long-term habituation was observed when the same food was presente

286 Additionally habituation was predicted from 15 physico-chemical and p

287 Furthermore, deficient amygdala habituation was significantly related to increased expos

288 neurochemical pathways underlying short-term habituation, we screened 1,760 bioactive compounds with

289 ice showed impaired exploratory activity and habituation when introduced to novel environment.

290 s serotonin content in DRN neurons increases habituation, whereas serotonergic agonism or DRN activat

291 f chronic stress is the phenomenon of stress habituation, which frequently reduces multiple stress-ev

292 aling exhibited blunted basolateral amygdala habituation, which further mediated increased risk for a

293 thin alpha'/beta' neurons leads to defective habituation, which is readily reversible by administrati

294 Here, we focus on long-term habituation, which, due to the extended time course, nec

295 hibiting IGF1R function in wild-type reduces habituation, while activation of IGF1R downstream effect

296 turbation of the eye trajectory did not show habituation with repetition, and was present in both pro

297 to molecular mechanisms engaged in footshock habituation within distinct MB neurons.

298 is thaliana plants that produce EBF leads to habituation within three generations.

299 cognitive impairments, including deficits in habituation, working memory and associative learning.

300 In olfaction, the main question is whether habituation works the same way for any odorant or whethe