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1 lagen-binding phenotype was unique to the Dr haemagglutinin.
2 ues surrounding the receptor-binding site of haemagglutinin.
3 the immunodominant receptor binding protein, haemagglutinin.
4 e ruptured with membrane edges stabilized by haemagglutinin.
5 binding domains of the viral surface protein haemagglutinin.
6 etion mutation in fhaB, encoding filamentous haemagglutinin.
7 ce and structural homology with conventional haemagglutinins.
8 oorly immunogenic and doses of 7.5-30 microg haemagglutinin alone are unlikely to give protection fro
10 eins of 37-43 residues that target influenza haemagglutinin and botulinum neurotoxin B, along with 6,
11 ng pose of designed VHHs targeting influenza haemagglutinin and Clostridium difficile toxin B (TcdB).
12 on-replicating, adenovirus vector expressing haemagglutinin and double-stranded RNA adjuvant delivere
13 t differs from the bundles described for the haemagglutinin and HIV/SIV gp41 membrane-fusion proteins
14 t of antigen localization, as membrane-bound haemagglutinin and I-Ealpha are also not presented by MH
17 s, with the remaining two genes encoding the haemagglutinin and neuraminidase proteins of a prototypi
19 e as the six viral RNA segments not encoding haemagglutinin and neuraminidase) that support high yiel
20 with single or multiple substitutions in H9 haemagglutinin and test binding to avian and human recep
21 B, the first two activities are mediated by haemagglutinin and the third by a second glycoprotein, n
22 nantly to the highly variable head region of haemagglutinin and their effectiveness is limited by vir
23 cines stimulate neutralising antibody to the haemagglutinin antigen but as there is antigenic drift i
24 We aimed to test the ability of chimeric H1 haemagglutinin-based universal influenza virus vaccine c
25 signed to one of three prime-boost, chimeric haemagglutinin-based vaccine regimens or one of two plac
29 as resulted in the rigorous investigation of haemagglutinin, but whether neuraminidase (NA) has under
30 : this requires interactions of the BCR with haemagglutinin, causing both disruption of antibody secr
31 ighly pathogenic avian influenza (HPAI) H5N1 haemagglutinin clade 2.3.4.4b was detected in the USA in
32 are associated with high virulence from the haemagglutinin cleavage site of A/Hong Kong/213/03 using
35 bat influenza A virus envelope glycoprotein, haemagglutinin, does not bind the canonical influenza A
36 sis of intragroup variants comprising the Dr haemagglutinin (DraE) group revealed that the point muta
37 rmational rearrangement of newly synthesized haemagglutinin during transport to the cell surface by e
40 nfluenza C virus, a single glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, possesses
41 contains a single surface glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, that media
42 tem domain is similar to that of influenza A haemagglutinin, except that the triple-stranded, alpha-h
44 es against pertussis toxin (PT), filamentous haemagglutinin (FHA) and pertactin (PRN) were evaluated
45 B. pertussis mutants lacking filamentous haemagglutinin (FHA) released significantly more AC toxi
46 osed and secreted protein called filamentous haemagglutinin (FHA) that functions in adherence and imm
51 accine candidate (Ad4-H5-Vtn) expressing the haemagglutinin from an avian influenza A H5N1 virus.
52 an adjuvant during vaccination of mice with haemagglutinin from the influenza virus, the particles e
53 dy conducted in pigs, describing part of the haemagglutinin gene (HA1) of an influenza virus, we find
54 en nucleotides at different positions in the haemagglutinin gene, allowing for the analysis of popula
55 certain packaging signals, most notably the haemagglutinin gene; this finding has major implications
57 d and screened LAMP primers targeting the H5-haemagglutinin (H5-HA) gene of AIV and fine-tuned the pa
59 , viruses were produced containing the viral haemagglutinin (HA) and neuraminidase (NA) genes of the
60 ting the carboxylation modification of viral haemagglutinin (HA) and the adhesion of progeny viruses,
61 ost-cell death is positively correlated with haemagglutinin (HA) binding affinity to NeuAcalpha2-6-Ga
62 criptional regulation of one specific vsp, a haemagglutinin (HA) epitope-tagged h7 was integrated int
63 ned by multi-colour flow cytometry for viral haemagglutinin (HA) expression and cell surface markers
64 ements of the receptor-binding properties of haemagglutinin (HA) from the transmissible mutant indica
65 n influenza virus, hundreds of copies of the haemagglutinin (HA) fusion glycoprotein project from the
68 t, although within-host genetic diversity in haemagglutinin (HA) increases during replication in inoc
72 the resultant production of recombinant 1918 haemagglutinin (HA) protein antigen to characterize at t
73 ognize invariant structures on the influenza haemagglutinin (HA) protein have invigorated efforts to
76 gned to co-display four recently circulating haemagglutinin (HA) strains; however, current vaccine an
77 fection is mediated via binding of the viral haemagglutinin (HA) to terminally attached alpha2,3 or a
79 -anchored subunit HA2 of the influenza virus haemagglutinin (HA) was solubilized by adding the very p
80 za, the receptor-binding glycoprotein is the haemagglutinin (HA), and following receptor-mediated upt
81 utathione S-transferase (GST)-Rad23 and Rad4-haemagglutinin (HA), and the proteasome subunits Cim3 an
82 tallography of the receptor-binding protein, haemagglutinin (HA), in complex with receptor analogues
83 influenza vaccine (ccIIV4), and recombinant haemagglutinin (HA)-based quadrivalent seasonal influenz
87 ed (1:1) to receive either HD-IIV (60 mug of haemagglutinin [HA] antigen per strain) or SD-IIV (15 mu
88 ined the three-dimensional structures of the haemagglutinins (HAs) from H5 avian and H9 swine viruses
89 e responses to current vaccines focus on the haemagglutinin head domain, whereas next-generation vacc
90 cles(4) carrying wild-type haemagglutinin or haemagglutinin hemifusion mutant G1S(5) and liposome mix
91 re anti-pertussis toxin and anti-filamentous haemagglutinin IgG concentrations in infants at delivery
92 tric mean concentrations of anti-filamentous haemagglutinin IgG were higher with increasing gestation
94 after 1968, cross-reacted between H7 and H3 haemagglutinins in binding assays, and had accumulated s
97 doses of 7.5 microg, 15 microg, or 30 microg haemagglutinin influenza A H9N2 vaccine, were given 3 we
99 ith LAIV strain shedding at day 2 and day 7, haemagglutinin inhibition seroconversion, and an increas
100 , manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in
101 ies function as cell-entry receptors for the haemagglutinin-like H18 protein of the bat H18N11 influe
102 gainst influenza B viruses belonging to both haemagglutinin lineages and spanning over 70 years of an
103 ized plasticity of the bat influenza A virus haemagglutinin means the tropism and zoonotic potential
105 related Type IV pili, the mannose-sensitive haemagglutinin (MSHA) pilus, which aids V. cholerae pers
109 H10 we have determined the structure of the haemagglutinin of a previously isolated avian H10 virus
110 harbour B cells with a BCR specific for the haemagglutinin of influenza A/WSN/33 virus (FluBI mice).
111 protective monoclonal antibodies against the haemagglutinin of influenza B viruses have been describe
112 particle immunogens that co-display the four haemagglutinins of licensed quadrivalent influenza vacci
113 tralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential
114 a virus-like particles(4) carrying wild-type haemagglutinin or haemagglutinin hemifusion mutant G1S(5
115 tinin per H3N2 vaccine strain, and 15 mug of haemagglutinin per B vaccine strain) (1) by microneedle
116 vated influenza vaccine (fluvirin: 18 mug of haemagglutinin per H1N1 vaccine strain, 17 mug of haemag
117 gglutinin per H1N1 vaccine strain, 17 mug of haemagglutinin per H3N2 vaccine strain, and 15 mug of ha
119 ith the proportion of variables representing haemagglutinin positions decisively included, or exclude
120 random mutations in the globular head of the haemagglutinin protein (which includes the antigenic sit
123 decreased the net positive charge around the haemagglutinin receptor-binding site show increases and
124 ding analyses showed stepwise changes in the haemagglutinin receptor-binding specificity of the EA sw
125 lic acid binding site and made contacts with haemagglutinin residues that were conserved in the great
126 protective antibodies in complex with the H7 haemagglutinin revealed that they recognize overlapping
128 2 viruses, on the basis of analyses of 9,604 haemagglutinin sequences of human seasonal influenza vir
129 outcome of interactions between an influenza haemagglutinin-specific B cell via its receptor (BCR) an
131 seroconversion, and an increase in influenza haemagglutinin-specific IgA and T-cell responses at day
135 tural data demonstrate that they bind to the haemagglutinin stem through conserved heavy-chain comple
140 ntibodies to two highly conserved vulnerable haemagglutinin structures that are targets of universal
141 -incompetent, human adenoviral-vector-based, haemagglutinin subtype 5 influenza vaccine (HAd-H5HA), w
142 charged amino-acid at position 54 of the Dr haemagglutinin subunit for chloramphenicol sensitivity o
145 iven 3 weeks apart, of 7.5, 15, or 30 microg haemagglutinin surface-antigen influenza A H5N3 vaccine.
148 PC3M cells that had been co-transfected with haemagglutinin-tagged HIF-1alpha and wild-type p53 also
150 a strategy to identify amino acids in the Dr haemagglutinin that are specifically involved in the int
151 ions in the receptor-binding site of the H10 haemagglutinin that decrease its avidity for avian recep
152 a designed binder in complex with influenza haemagglutinin that is nearly identical to the design mo
154 We tested whether conjugating influenza haemagglutinin to transferrin could improve the immune r
155 racellular polysaccharide, mannose-sensitive haemagglutinin type 4 pili and polar (but not lateral) f
156 e surface itself activates mannose-sensitive haemagglutinin type IV pilus (MSHA)-mediated attachment,
157 hesis and secretion of the mannose-sensitive haemagglutinin type IV pilus (MSHA); (ii) the synthesis
158 umans by an oil-in-water adjuvanted chimeric haemagglutinin vaccine(4,5), which is a potential univer
159 ng a broadly neutralizing antibody targeting haemagglutinin via the optimized LNP protected mice from
162 antibodies that bind to the globular head of haemagglutinin, which undergoes a continuous antigenic d
163 structure of the complex formed by avian H10 haemagglutinin with human receptor, it is clear that the
164 lent amounts of virus through interaction of haemagglutinin with surface-disposed sialic acids, the A