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1 ish (cyclostomes, represented by lamprey and hagfish).
2 ymphocyte receptor of the jawless vertebrate hagfish.
3 ecame cyclostomes, which include lamprey and hagfish.
4 metals can be taken up by the integument of hagfish.
5 VLR genes (VLRA and VLRB) have been found in hagfish.
6 d are orthologs of Wnt9 genes from shark and hagfish.
7 g, striped bass, thresher shark, and Pacific hagfish.
8 ebrate group Agnatha, including lampreys and hagfishes.
9 two VLR isotypes occurs in both lampreys and hagfishes.
10 ste buds was previously known in the skin of hagfishes.
11 like cells, but not on erythrocytes from the hagfish, a primitive agnathan vertebrate lacking markers
15 ation pattern whereas primitive vertebrates (hagfish and lamprey) have patterns that are typical of v
16 As such, the genomes of the jawless fish (hagfish and lamprey) offer the best possibility for find
20 racters, our phylogenetic analyses recovered hagfish and lampreys in a clade of cyclostomes (congruen
21 surveys, that Cyclostomata is monophyletic: hagfish and lampreys share 4 unique microRNA families, 1
22 4A6 genes coincided with kidney emergence in hagfish and shark and that the COL4A3 and COL4A4 were lo
23 e only surviving lineages of jawless fishes, hagfishes and lampreys provide a crucial window into ear
24 lso suggest that the last common ancestor of hagfishes and lampreys was a macrophagous predator that
25 (jawed vertebrates) and cyclostomes (jawless hagfishes and lampreys) is unresolved and whether these
27 he living jawless vertebrates (cyclostomes), hagfishes and lampreys, provide scarce information about
28 yclostomes (jawless vertebrates-lampreys and hagfish) and gnathostomes (jawed vertebrates-cartilagino
29 microRNA expression patterns among lamprey, hagfish, and gnathostome organs, implying that the role
31 ) of jawless vertebrates such as lamprey and hagfish are composed of highly diverse modular leucine-r
34 ed a BAFF-like gene in lampreys, which, with hagfish, are the only extant jawless vertebrates, both o
35 ing jawless vertebrates such as lampreys and hagfishes, are the sister group of living jawed vertebra
38 was obtained from mRNA isolated from Pacific hagfish brain using rapid amplification of cDNA ends (RA
40 ue anatomy includes key attributes of living hagfish: cartilages of barbels, postcranial position of
44 phylogeny places the fossil taxon within the hagfish crown group, and resolved other putative fossil
46 l of this study was to determine whether the hagfish endothelium displays phenotypic heterogeneity.
49 Here we show that the brain of the inshore hagfish (Eptatretus burgeri), another cyclostome group,
50 g an in vitro technique, the skin of Pacific hagfish (Eptatretus stouti) was shown to take up nickel
53 uirts, the closest invertebrate relatives of hagfish, failed to reveal evidence of an intact vwf gene
54 es.(9) Here, by sampling a range of sizes of hagfish from 19 species, we systematically examined the
56 fish, and further studies of the lamprey and hagfish genomes will determine just how explosive the Bi
59 ver, in the most basal extant craniates, the hagfishes, gills play only a minor role in gas exchange.
60 l and physiological constraints.(1)(,)(2) In hagfishes, gland thread cells (GTCs) each produce a silk
61 ction for stronger defensive slime in larger hagfishes has driven the evolution of extreme size and a
63 e characterize programmed DNA elimination in hagfish, identifying protein-coding genes and repetitive
64 ranch problem or the evolutionary history of hagfish in general, because unequivocal fossil members o
65 surviving jawless vertebrates, lampreys and hagfish, instead solved the receptor diversification pro
67 21) the evolutionary history of lampreys and hagfishes is a major frontier of organismal biology.
68 immunity in jawless vertebrates (lamprey and hagfish) is mediated by lymphocytes that undergo combina
69 te systems and the Schreiner organ system of hagfishes, it is concluded that Schreiner organs are not
71 e of Xenopus lymphocytes and tumor cells and hagfish lymphocyte-like cells by a process that requires
72 fish (Opsanus tau), chicken (Gallus gallus), hagfish (Myxine glutinosa), horseshoe crab (Limulus poly
74 nctional vwf gene is present in the Atlantic hagfish, Myxine glutinosa We found a single vwf transcri
76 brates and appears to be a specialization of hagfishes, perhaps derived from the primitive somatosens
78 All extant jawless vertebrates (lampreys and hagfishes) possess a unique adaptive immune system chara
80 ons, which led us to hypothesize that larger hagfishes produce longer and stronger slime threads than
83 ylogenetic relationships within lampreys and hagfishes remain unclear,(13)(,)(14)(,)(15) and the ages
85 ,)(4) The slime threads impart strength to a hagfish's defensive slime and thus are potentially subje
92 Our results support an epidermal origin of hagfish slime, which may have been driven by selection f
93 e orthologous VLR genes in both lampreys and hagfish suggests that this anticipatory receptor system
96 nd the presence of two types of VLR genes in hagfish, the only other order of contemporary jawless ve
97 of vertebrate cartilage, and we report that hagfishes, the sister group to lampreys, also have Col2a
102 ylogenetic analysis indicate that the unique hagfish VLR is the counterpart of lamprey VLRA and the p
107 for a burrowing, benthic scavenger, such as hagfish, which are likely to be exposed to relatively en