ライフサイエンスコーパス: handful

1 dels, previous research suggests that only a handful are evolutionarily stable against invasion by fr

2 tes range from 15 to 20 channels, and only a handful are functionally understood.

3 (NBs) in bacteria of which, to-date, only a handful are known.

4 takes about 1 s to fuse two bilayers, yet a handful can ensure release of neurotransmitters from syn

5 fore, regular consumption (approximately one handful daily) of nuts over the long term, as a replacem

6 ctions of Holocene climate in Europe, only a handful has addressed winter conditions, and most of the

7 ave been predicted bioinformatically, only a handful has been thoroughly characterized.

8 oduct antibiotics discovered to date, only a handful have been developed for the treatment of bacteri

9 hundred grains and boundaries, where only a handful have been previously reported.

10 encode roughly 70 F-box proteins, but only a handful have established functions.

11 It is one of a handful molecules that can expose new recognition sites

12 vidence of pervasive cotargeting, in which a handful of "hub" microRNAs are involved in a majority of

13 Only a handful of 3d(n) metal complexes (n != 10) show sizable

14 ndidate gene-based studies have identified a handful of aberrant CpG DNA methylation events in prosta

15 of brain function, with fMRI showing only a handful of activated regions in response to task/stimula

16 hundreds of pre-clinical candidates, only a handful of adjuvants are approved for prophylactic vacci

17 Only a handful of adjuvants have both sufficient potency and ac

18 networks are almost entirely aligned with a handful of aligners that we unify into a new tool, Ulign

19 tions in neuroscience best studied in only a handful of animal models?

20 A handful of animals, notably the fungus-growing ants, ter

21 steries remain about its key protagonists, a handful of Anopheles species.

22 s (Nucleotides or Amino Acids) or for only a handful of application use-cases.

23 Clusters containing only a handful of atoms have been the subject of extensive theo

24 ge of challenging physical puzzles in just a handful of attempts.

25 d's oceans and taxonomically restricted to a handful of bacterial genera.

26 striking is the direct juxtaposition of the handful of bacterial model organisms to the 1000 prokary

27 Despite its evolutionary importance, only a handful of bacterial, genome-wide cytosine studies have

28 The Co-Optima program has identified a handful of biofuel compounds from a list of thousands of

29 Px data for one or more TF(s) in more than a handful of biological contexts.

30 Since 2003, a handful of biological systems have been identified to di

31 ojecting the large TCR sequence space into a handful of biophysicochemical descriptors for key residu

32 Only a handful of bird species are known to use foraging tools

33 Only a handful of broadly applicable reporters have been identi

34 To date, though, only a handful of broadly useful transformations have been iden

35 Examples include metabolism where a handful of building blocks mediate between multiple inpu

36 is and degradation in enterobacteria, only a handful of c-di-GMP receptors/effectors have been identi

37 A infectivity phenotypes due to fewer than a handful of CA amino acid differences and that these clon

38 zeolite structures led to the discovery of a handful of candidates that have sufficient methane sorpt

39 calcinosis has rarely been made, with only a handful of cases described in literature.

40 actitioner as no center will see more than a handful of cases each year.

41 llimolar dissociation constants, relies on a handful of cases in which weak encounters have experimen

42 e have only been observed in cells, but in a handful of cases structural and biochemical studies have

43 oups in proteins has been achieved in only a handful of cases, which typically have involved comparat

44 these changes has been elucidated in only a handful of cases.

45 gulatory antagonism previously observed in a handful of cases.

46 limited the availability of this method to a handful of centers around the world.

47 spread use in Asia, but remains limited to a handful of centers in North America and comprises only 5

48 We also identify a handful of characteristics that drive nanoscientists' in

49 However, only a handful of CID systems exist and creating one with the d

50 circRNA from the MDM2 locus, was one of the handful of circRNAs that originated from a p53-induced g

51 oxidase, but HV 1 were known only to a tiny handful of cognoscenti around the world.

52 A handful of commercial and freely available software prog

53 metallic neptunium chemistry, and yet only a handful of complexes have been reported, and even fewer

54 roducts were determined to consist of only a handful of compounds that quickly polymerize to form anh

55 depends on the reliability of results from a handful of computational techniques, structural alignmen

56 hese hypokalemia-mediated changes occur in a handful of conditions including primary aldosteronism, d

57 We registered only a handful of conserved intronic ncRNAs of flowering plants

58 The discovery of a handful of conserved signaling pathways that dictate mos

59 dissociation free energy (BDFE), yet only a handful of copper-bound O-H bond strengths have been def

60 A handful of core intercellular signaling pathways play pi

61 nectedness, "importance") were observed in a handful of cortical regions.

62 As one of only a handful of countries that have achieved both Millennium

63 tudent persistence and completion rates in a handful of courses, but evidence of their effectiveness

64 tiffness 0.025 pN/nm) and mediated by only a handful of cross-links.

65 However, identification of one or a handful of decay events within a large mass of candidate

66 ry' returns over 2500 references, yet only a handful of delivery systems have been successfully trans

67 e nucleophilic aluminyl anion is feasible, a handful of derivatives have been developed to date, whic

68 ckground of global 5hmC loss we identified a handful of developmentally important genes that maintain

69 Vaccines are based on a handful of different designs (i), but the earliest vacci

70 x 6 represents an intriguing addition to the handful of diiron(IV) complexes that have been character

71 Among a handful of drug-resistant mutants, M2-S31N is the predom

72 Among the handful of drug-resistant mutants, S31N is found in more

73 for HCC is exceedingly limited, with only a handful of drugs providing benefit.

74 -lactam antibiotic ceftazidime is one of the handful of drugs with proven clinical efficacy against t

75 However, only a handful of early chondrichthyan gill skeletons are known

76 renorphine is available in prisons in only a handful of EECA countries (methadone or buprenorphine in

77 Only a handful of endogenous peptide defense signals have been

78 However, only a handful of endogenous proteins encoded by putative lncRN

79 ntal and applied polymer science, yet only a handful of equilibrium morphologies are known with the s

80 A handful of error correction methods for these error-pron

81 ral genomes, it has been observed for only a handful of eukaryotic genes.

82 ns is unknown, but initiator proteins from a handful of eukaryotic viruses can perform this function.

83 stigation of SMC AS has been restricted to a handful of events.

84 There are now a handful of examples of intestinal commensal bacteria wit

85 Presently, there are only a handful of examples of protein dendrimers; we believe th

86 decades of research, however, we have only a handful of examples where reciprocal coevolutionary chan

87 Apart from a handful of examples, however, the chemistry of these com

88 Only a handful of exceptional examples are known, typically inv

89 Drawing on a small handful of exemplary studies, we review some of the majo

90 tral features have, however, been found in a handful of exotic NSs and were thought to be a manifesta

91 While this limits glycan analysis to a handful of experts, the increasing awareness of the trem

92 While a handful of Fe(II)- and 2-oxoglutarate-dependent halogena

93 ade Hampton Frost (1919-1938), was among the handful of foundational thinkers in the discipline of ep

94 A handful of free-floating planetary-mass objects have bee

95 sis suggests that substantial expansion of a handful of gene families, along with extensive remodelli

96 For decades, a handful of gene markers have given us a glimpse of the g

97 Indeed, among a handful of general strategies for synthesizing such supr

98 monstrate that the hybrid method with only a handful of generations of the DTWF model leads to a freq

99 Prior molecular efforts have focused on a handful of genes but have provided little resolution to

100 stablished disease-causing DNA variants in a handful of genes have evolved into sequencing factories

101 igh frequency of heart valve disease, only a handful of genes have so far been identified as the mono

102 Only a handful of genes showed evidence for sequence adaptation

103 To date, only a handful of genes that control polarized localization of

104 n identified in clinical studies as one of a handful of genes whose altered expression levels or alle

105 ses in the utilization frequencies of just a handful of genes, and these genes have no clear position

106 However, a handful of genes, including the homologous genes LNK1 an

107 aberrations and the recurrent mutation of a handful of genes, such as TP53, ATM, and CCND1.

108 by HIV proviral DNA integrated into one of a handful of genes.

109 It is known that such resistance relies on a handful of genetic lesions and/or extracellular signals

110 However, as only a handful of genetic risk factors have been investigated b

111 an only handle a small number of loci from a handful of genomes.

112 In contrast, only a handful of GWAS of PTSD have appeared in the literature

113 nce and memory are limited and includes only handful of hash table (BLAT, SSAHA2) or trie (Burrows-Wh

114 Animal embryos are patterned by a handful of highly conserved inductive signals.

115 d previous studies on mRNA decay have used a handful of highly expressed transcripts as models.

116 In the protein kinase field, only a handful of highly selective allosteric modulators have b

117 enotypes, requiring only the inspection of a handful of images per phenotype for validity.

118 Despite these striking phenotypes, only a handful of imprinted genes are known or suspected to reg

119 n 2011, extends into southern Kenya, where a handful of individuals survive in the Masai Mara.

120 disorders through analysis of a single or a handful of informative pedigrees.

121 By comparison, only a handful of innate visual behaviors are known in this spe

122 Recently, a handful of intergenic long noncoding RNAs (lncRNAs) have

123 ered on English as a global hub and around a handful of intermediate hub languages, which include Spa

124 s encompass large surface areas, but often a handful of key residues dominate the binding energy land

125 y across plant ecological strategies using a handful of key traits.

126 e progress made in this area is limited to a handful of known cases of small molecules that target sp

127 However, there are only a handful of known commensal strains that can potentially

128 sulfur response regulator, SurR, is among a handful of known redox-active transcriptional regulators

129 Although there are a handful of known riboswitches, our knowledge in this fie

130 lence or marker genes is mainly focused on a handful of known species, and shotgun metagenomics is li

131 Although effects are convincingly shown in a handful of lab studies, sublethal effects at environment

132 Only a handful of Lactobacillus species is found in caries lesi

133 In neuroblastoma, only a handful of lincRNAs are known as upstream regulators or

134 ggregates of cells, it has evolved only in a handful of lineages, including animals, embryophytes, re

135 nd/or FISH imaging that typically features a handful of low resolution probes.

136 was implemented by Portuguese who imported a handful of macaques from Java to Mauritius Island.

137 owever, these studies were limited to only a handful of mammalian origins, and it remains unclear how

138 fic loci led to the identification of only a handful of mammalian replication origins.

139 techniques were used to sequence the Y for a handful of mammalian species.

140 derlying mechanisms remain contentious, as a handful of markers usually provides little power to dete

141 an exotic phenomenon previously limited to a handful of materials at low temperatures.

142 Z) geometry is predominant in nature, only a handful of metabolites containing (E)-Dhb have been foun

143 ription factor, one usually has to compare a handful of methods.

144 IvERGE), are however, currently limited to a handful of microorganisms for which single-stranded DNA-

145 ons (NTA) are a common phenomenon, and for a handful of miRNAs the additions have been demonstrated t

146 to link genes to phenotypes is based upon a handful of model microorganisms.

147 ge of Y chromosome sequences is limited to a handful of model organisms, constraining our understandi

148 Despite the observation of a handful of modified viral RNAs five decades ago, very li

149 s of SIRT6 in physiology and disease, only a handful of molecular and functional interactions of SIRT

150 strategies that concentrate on only one or a handful of molecular targets limits the utility of the i

151 nanomolar sensitivity and can measure only a handful of molecules, such as glucose and blood oxygen.

152 memory consolidation remain restricted to a handful of molecules.

153 usceptibility to Parkinson's disease, only a handful of monogenic causes of parkinsonism have been id

154 To date, only a handful of mt-RBPs have been characterized.

155 C) by constructing and characterizing only a handful of multiple-point mutants.

156 , and its scope has been limited by the mere handful of natural combinations.

157 es of these polymers is lacking, with only a handful of natural structures sequenced to date.

158 n has proven extremely difficult with only a handful of NMR-based models proposed, suggesting a need

159 ies have linked color pattern variation to a handful of noncoding regions, yet the presumptive cis-re

160 A handful of novel drop-in replacement biofuels for conven

161 peptidase, using this approach identified a handful of novel endogenous DPP4 substrates.

162 ock powerful global plant predictions from a handful of open-access field measurements.

163 ton, is a characteristic reserved for only a handful of organic molecules due to the atypical energet

164 t two decades, large-scale PPI networks of a handful of organisms were determined by experimental tec

165 sin), ZFYVE26/SPG15, SPG7 (paraplegin) and a handful of other rare genes, but many cases remain genet

166 modest, the stability of sensors employing a handful of other reporters, including anthraquinone, Nil

167 ved fossil biotas of the Burgess Shale and a handful of other similar Cambrian deposits provide rare

168 n living organisms, is represented only by a handful of papers.

169 By collapsing structural diversity to a handful of parameters, such methods can be used to delin

170 mizing model hyperparameters only requires a handful of passes through the data.

171 A handful of pediatric patients undergoing sequential LT a

172 Currently only a handful of people worldwide have undergone this procedur

173 Most functional biomaterials are based on a handful of peptide sequences derived from protein ligand

174 ered biomaterials have been generated from a handful of peptides that were selected and exploited for

175 To date, only a handful of phosphoproteins with important biological fun

176 However, only a handful of pioneering studies describe the dynamics of p

177 t that these studies all fall prey to only a handful of pitfalls.

178 tissue-specific roles have been shown for a handful of plant ARF-GEFs, a fundamental yet unanswered

179 However, only a handful of plant signaling peptides have been reported.

180 imited, hierarchical pedigree diagrams for a handful of plant varieties.

181 only few multicellular species, limited to a handful of plants and animals, have been shown to fulfil

182 However, only a handful of polymeric biomaterials are utilized today bec

183 ributions to circadian rhythmicity made by a handful of post-translational mechanisms, such as phosph

184 We identified a handful of potential recombination-associated sequence m

185 tion with ribosome profiling we identified a handful of previously unknown non-AUG initiation sites,

186 For example, marmosets are among only a handful of primates that, like humans, routinely pair bo

187 ntheses of life's key building blocks from a handful of primordial substrates.

188 The use of a handful of probes has already revealed an amazing specif

189 ical indications and directed against only a handful of protein and lipid kinases, leaving 70% of the

190 ase stretches of satellite DNA repeats and a handful of protein-coding genes that are monomorphic wit

191 However, only a handful of proteins carrying Hcy on specific lysine resi

192 se from protein pockets are only known for a handful of proteins.

193 In contrast to FTase and GGTase I, only a handful of RabGGTase inhibitors have been developed.

194 To date, only a handful of radiogenomics studies have been performed to

195 e autoantibodies (ACAAs) are pathogenic in a handful of rare immunodeficiencies.

196 Imine bond formation is one of a handful of reactions which define a discipline known as

197 ing CRISPR screens in plants and analyze the handful of recent reports using this strategy to generat

198 information in living cells, but only for a handful of recombinant proteins at a time, whereas the l

199 n intergroup context is built around a small handful of recurrent interaction types.

200 tions are less well-characterized and only a handful of recurrent non-coding mutations, most notably

201 ough the structure of many P450s and a small handful of redox partners are known, there is very littl

202 Overall, our results show that a handful of regions carry most of the mutations acquired

203 ure is of a highly subdivided species with a handful of relatively clonal groups (complexes) that, at

204 m the recent massive amplification of just a handful of repeat families, as shown in species with sma

205 While a handful of reports have demonstrated the potential of su

206 A handful of reports have shown that innate immune respons

207 , radiation, intravesical agents) based on a handful of retrospective case series.

208 e time dimension, data are reduced to only a handful of scans around each peak apex.

209 ng nonribosomal peptide and is one of only a handful of secondary metabolites described from obligate

210 A synthesis through STRs are restricted to a handful of selected sequences, limiting our broader unde

211 ily interpretable when analyzing more than a handful of sequences.

212 revious one covering glycans released from a handful of serum glycoproteins, has more than 170 comple

213 Yet, its value has been measured only for a handful of simple lipids, and no simulation has so far d

214 , these behaviors have only been tested in a handful of size dimorphic spiders.

215 Only a handful of small molecules that antagonize the action of

216 Fingerprinting of donor L1s revealed that a handful of source L1 elements in a tumor can spawn from

217 Although a handful of sparse vegetation records exists from middle

218 cadmium and arsenic is only experienced in a handful of special habitats.

219 fied across every continent on Earth, with a handful of species (rice [Oryza sativa], maize [Zea mays

220 ficient replication origin modules to only a handful of species and restricts our understanding of or

221 a result, studies have largely focused on a handful of species for which strong evidence for vocal l

222 ly divergent or uniquely present in one or a handful of species, hampering efforts to determine the g

223 nging technology that is available only in a handful of species.

224 c do not have P450s, with the exception of a handful of Staphylococcus species that have a single P45

225 k drive, and prior drive are controlled by a handful of state parameters, which I hypothesize corresp

226 gy to make predictions constrained by just a handful of state variables, like total abundance or spec

227 Although a handful of stellar mergers have been observed directly(8

228 nfective larvae released from snails carry a handful of stem cells that serve as the likely source of

229 However, there are currently only a handful of strategies for engineering such regulatory co

230 rene functionalization, but there are only a handful of strategies for para-selective borylation, whi

231 C subtypes in animal models, although only a handful of studies demonstrate the differential loss of

232 Yet there are only a handful of studies demonstrating control of electronic i

233 se variants are associated with disorders, a handful of studies documented an adaptive advantage conf

234 However, to date, only a handful of studies empirically tested its applicability

235 search has focused on candidate-genes with a handful of studies employing whole transcriptome approac

236 n organic transformations, but so far only a handful of studies have addressed their potential use as

237 A handful of studies have begun to explore the reverse inf

238 To date, only a handful of studies have directly determined the infectio

239 Despite this, only a handful of studies have examined brain variation across

240 Only a handful of studies have examined the anatomy of the VOF

241 To date, only a handful of studies have explored the emotional impact of

242 Although a handful of studies have found selective responses to sce

243 ncision wound during feeding and, although a handful of studies have targeted certain anticoagulants,

244 e and in contrast to transcriptomics, only a handful of studies in crop plants engaged with global pr

245 ) HDX-MS has become common, there are only a handful of studies reporting the systematic evaluation o

246 d DNA double-strand breaks, there are only a handful of studies that report precise editing of endoge

247 To our knowledge, this is one of only a handful of studies to document a nonmonotonic dose respo

248 af thermoregulation has been documented in a handful of studies, but the generality and origins of th

249 IPCC 2006 default rates come from a handful of studies, provide no uncertainty indications a

250 Few country-level studies and a handful of subnational studies from the United States, J

251 for cell cycle progression; however, only a handful of substrates are currently known.

252 A handful of successful d-block metal catalysts have been

253 h activation occurring in response to only a handful of such binding events, individual cells are unl

254 sms of sex determination is known for only a handful of such species, but, in those that have been in

255 quamous cell carcinomas and pointed toward a handful of targetable alterations.

256 However, the mere handful of targets that have been identified barely begi

257 hromosomes have only been generated across a handful of taxa with highly degenerate sex chromosomes.

258 works are at best weakly scale free, while a handful of technological and biological networks appear

259 Unexpectedly, only the repression of a handful of TFs significantly affected transcriptomes, wh

260 No such vaccine currently exists, and only a handful of the hundreds of potential candidates in the p

261 on a regular basis, we would like to share a handful of the many lessons that we have learned in our

262 Only a handful of the more than 100,000 fungal species on our p

263 peptides or proteins, many of these target a handful of the most reactive proteinogenic amino acids.

264 s to adopt the strategy of confirming only a handful of the most statistically significant results, a

265 ing drug compounds and successfully tested a handful of the top-ranking molecules in C. elegans survi

266 Since endocrine cells only contain a handful of these channels, it is likely that stochastic

267 To this day, only a handful of these compounds have been synthesized, but mo

268 via biochemical annotations; however, only a handful of these have been validated and confidently lin

269 ch-evoked spike counts of a randomly sampled handful of these neurons.

270 However, only a handful of these potential pharmacological targets have

271 However, only a handful of these studies tested infants while they were

272 h common diseases and complex traits, only a handful of these variants are validated to be causal.

273 quantitative data, on the other hand, only a handful of tools exist, and the computational burden is

274 ts; however, due to fairly large SEs, only a handful of trait pairs yielded statistically significant

275 itted somatic cells using a combination of a handful of transcription factors, such as OCT3/4, SOX2,

276 We show that a handful of transnational corporations have become a majo

277 A handful of trials are targeting non-CD19 hematological a

278 al conception just over a decade ago, only a handful of trials have been completed assessing the effi

279 A handful of tumor-derived cell lines form the mainstay of

280 Despite the promise of these systems, only a handful of unique crystal scaffolds have been reported.

281 , data are reduced from a full spectrum to a handful of unique ions for each chromatographic peak.

282 A handful of unique toehold activation mechanisms, includi

283 Despite extensive research, only a handful of vaccine adjuvants have been approved for huma

284 grees of freedom can be often described by a handful of variables.

285 proteins are found in many microbes, only a handful of variants are used for these applications.

286 arkable progress, our understanding of how a handful of viral proteins can completely overrun the mul

287 chemical, and biological systems, but only a handful of wavelengths are directly produced by solid-st

288 olding studies are generally restricted to a handful of well-behaved proteins.

289 Despite their utility, only a handful of well-characterized regulators exist, limiting

290 involving common alleles of small effect, a handful of which have now been definitively identified.

291 it is apparent that altered expression of a handful of Wnt pathway proteins occurs in or regulates a

292 t the results are limited in scope to just a handful of woody species in one part of the state and ar

293 Hoogsteen bps have been reported in a handful of X-ray structures of protein-DNA complexes.

294 Currently, only a handful of XNA structures have been archived in the Prot

295 and disaccharides per day) and sweets (i.e., handfuls of candies per day) in the UK Biobank sample (n

296 impairments were prevalent, with less than a handful showing deficits restricted to the writing tasks

297 , these hundreds of options reduce to a mere handful, some of which turn out to be identical.

298 of repeats in any one array can range from a handful to several hundreds.

299 parameters of almost 200 proteins, whereas a handful were known previously.

300 selected based on their activity, but only a handful with maximal activity have been traditionally id