ライフサイエンスコーパス: hardly

1 However, they were hardly able to activate the chemotaxis histidine kinase.

2 tional visual field of fixations can vary is hardly able to explain natural visual-search behavior.

3 s bitter and astringent flavour, propolis is hardly accepted by consumers.

4 Interestingly, certain conformers, hardly accessible for common calixarenes/thiacalixarenes

5 ual site of inflammation in asthma, which is hardly accessible in population studies.

6 experimental work is lacking, due in part to hardly accessible molecular length scales.

7 turation (such as selection permissiveness), hardly accessible through measurements.

8 y, on the molecular scale contact angles are hardly accessible.

9 exation, meso-1,5-cyclodecadiynes, otherwise hardly accessible.

10 ates experimental control, not requiring new hardly-accessible resources.

11 This objective, not pursued previously, is hardly achievable by experiments alone, since [Formula:

12 avily impacted environments is important but hardly achievable due to the difficulty of recovering su

13 d functionalities that a single material can hardly achieve.

14 g for future applications, has hitherto been hardly addressed experimentally.

15 s, the practice of food allergy education is hardly adequate, and the educational sites seem to recog

16 mamide), EtOH, or CO(2), etc., while N(2) is hardly adsorbed and does not open the narrow-pored form.

17 the non-covalent interactions with the host hardly affect the dihedral angles, validating that the h

18 Interestingly, Mn(2+) ions hardly affect the fluorescence emission of tC(o), wherea

19 An all-HFCV fleet would hardly affect tropospheric water vapor concentrations.

20 uced NO-induced fundus relaxation, which was hardly affected after ICC-specific deletion.

21 pectively, whereas human endothelial NOS was hardly affected at all.

22 st, the photopic ERG b-waves in KO mice were hardly affected at any age.

23 xtension or by weakening of filter paper but hardly affected binding to whole cell walls, which is me

24 ducer and activator of transcription 3) were hardly affected by 11.

25 rescence, and this extremely fast process is hardly affected by deuteration of exchangeable protons.

26 rption affinity of (iv) the neutral base was hardly affected by different electrolyte compositions, c

27 concentration of holes in the perovskite is hardly affected by optical excitation, which manifested

28 tion capacity for the hydrophobic polymer is hardly affected by the adsorption of water vapor.

29 The threading rate is hardly affected by the length of the PEG chains that fla

30 cies to be highly sensitive while others are hardly affected by the pyrethroids.

31 energy barrier to form the initial stalk is hardly affected by the radius of the vesicle, but that t

32 al activity increased pupal size, whereas it hardly affected pupariation timing.

33 ng decreases in the levels of all free VSCs, hardly affected the ability of the wine to release back

34 Results showed that pasteurization hardly affected the health related properties of tomato

35 Global Nrf2 knockout (Nrf2KO) hardly affected the onset of cardiac dysfunction induced

36 Temperature hardly affected the total amount of isoflavones.

37 The presence of ACR3 hardly affected tissue arsenic levels, but increased ars

38 enting the items in stereoscopic depth alone hardly affected VWM performance.

39 fa mRNA and IL-6 and TNF-alpha secretion was hardly affected, because the Toll/IL-1R domain-containin

40 d that the sublethally exposed cultures were hardly affected, while the cultures that were exposed to

41 +) sensitivities, Ca(2+) spark amplitude was hardly affected.

42 he life cycle end points of C. riparius were hardly affected.

43 atly modulated by attention while others are hardly affected.

44 nce marker levels in wild-type siliques were hardly affected.

45 nonspecific hydrophobic interactions, while hardly affecting the encounter rate, can significantly r

46 ate that orientation of the capture molecule hardly affects high-affinity interactions, while it lead

47 nd reduced P1 amplitude; TTX reduced P50 and hardly altered P1.

48 ver, determining these intermediate steps is hardly an easy feat, and has been elusive for most prote

49 Sn,Pb,Ge}{Cl,Br,I}(3), which could have been hardly anticipated without high-throughput means.

50 imposition of war reparations has attracted hardly any attention.

51 There are hardly any data about the frequency of CD4(+)CD25(+)Foxp

52 ession of IL-1RI in NM-C fibroblasts and had hardly any effect on NP-AERD fibroblasts.

53 s, whereas purification of the oil phase had hardly any effect.

54 an reduce the risk of suicide reattempt, but hardly any evidence about factors that protect against s

55 in the molecular configurations in solution, hardly any experimental data giving access to distributi

56 It infers hardly any extinction when collection dates are randomiz

57 g periodontitis (>/=1 site with PD >/=4 mm), hardly any false-positive results were identified.

58 At ratios of d(MP)/d(GS) > 0.32, hardly any infiltration could be observed.

59 There is hardly any information available about the molecular bas

60 Hardly any information exists about the properties of hu

61 selectively but also in some cases there are hardly any instances of a catalytic enantioselective add

62 dominated by neurological deterioration with hardly any involvement of other organs.

63 opean countries make up another cluster with hardly any maize trade with the US; and Argentina, Brazi

64 of proteins, overexpression of sRNAs imposes hardly any metabolic burden on cells, and constitutes a

65 the most diverse avian community (Estonia), hardly any models were attacked.

66 glec-15 expression on murine osteoclasts and hardly any other expression on various other immune cell

67 crystals on the fluid bilayer domains, while hardly any particles adhere to the more solid bilayer do

68 Specifically, hardly any prior testosterone experiments in humans scru

69 However, there have been hardly any representative long-term emission measurement

70 ms or milligrams in the laboratory, there is hardly any research addressing how these methods can be

71 Below this concentration, hardly any stress symptoms were observed.

72 to inhaled allergens in healthy airways but hardly any studies have addressed sensitization during e

73 used on these activities; however, there are hardly any studies that address its role as extractant.

74 benign conditions, and perennial plants show hardly any transgenerational responses at all.

75 affinities and association rates, there were hardly any variations in the dissociation rate constants

76 During latency, hardly any viral proteins are expressed to avoid recogni

77 Hardly anything important occurs in cells without the pa

78 and, to a lesser extent, cytosolic proteins, hardly anything is known about the SUMOylation of protei

79 Hardly anything is known about translational control of

80 biotic stress increase; this model has been hardly applied to animal communities.

81 adherence to guideline recommendations would hardly augment proportions of appropriate therapy, but c

82 he fast and accurate determination of CRP in hardly available clinical samples as those coming from p

83 nd accurate CRP determination (E(r) = 1%) in hardly available preterm babies' plasma samples with sus

84 strategies for reducing the contribution of hardly avoidable, nonspecific interactions to their resp

85 al complexes into gelator molecules that can hardly be achieved by pure organic compounds.

86 rage level for the population as a whole can hardly be achieved due to the effects of herd immunity.

87 of the environmental impact reductions will hardly be achieved in reality, particularly in the short

88 terials, such as coal, coke, or biochar, can hardly be analyzed by liquid state NMR due to their poor

89 r expensive synthesis processes and thus can hardly be applicable to other materials.

90 rolled composition and surface pressure) can hardly be avoided during standard cryo-EM specimen prepa

91 hat forgetting is a passive process that can hardly be controlled.

92 eans, although transport rates in rivers can hardly be determined yet.

93 ited by dissolution and availability and can hardly be determined.

94 ificance as a major regional carbon sink can hardly be disputed.

95 Therefore, their prediction results can hardly be explained by the mechanisms of epidemic spread

96 distinct physical/chemical properties could hardly be incorporated simultaneously into the synthesis

97 es, funding mechanisms, and governance could hardly be more different.

98 nd the six-layered neocortex structure could hardly be more dissimilar in appearance from the nuclear

99 remes whose value for climate adaptation can hardly be overemphasized, especially for the developing

100 he synthesis of complex molecules that would hardly be producible through conventional method.

101 he most basic tools as, for instance, it can hardly be recognized by enrichment analysis tools, nor c

102 variety of more specific functions that can hardly be related to their low-rate monotonous patterns

103 ever, is so weak (globally 1.2%) that it can hardly be relevant as compared with the radiative forcin

104 , have overestimated effect sizes and 3) can hardly be replicated in an independent sample.

105 stness, simplicity of operation and cost can hardly be rivalled by any other technique.

106 ion appears to be so straightforward that it hardly bears mentioning: like certain forms of adult ent

107 nd lichens for their associated food web has hardly been addressed [14, 15], despite the fact that nu

108 of the ED RNA dimer in HIV-1 replication has hardly been addressed because of technical challenges.

109 her chemical signals play a role as well has hardly been addressed.

110 geometry for an open channel water flow has hardly been established because of too many unknown vari

111 s applications, although their potential has hardly been explored due to their higher susceptibility

112 ration might play in virus transmission have hardly been explored.

113 erize photochemical processes, however, have hardly been explored.

114 lar ion species is very much desired but has hardly been explored.

115 nces of such transformed body ownership have hardly been explored.

116 biological phosphorus removal) systems have hardly been investigated and its potential link to EBPR

117 However, organic materials have hardly been investigated in this context even though car

118 However, these models have hardly been linked to the ill-understood neurobiological

119 areas in which modern medical practices have hardly been present with a USA group of mothers and thei

120 Tissue sublimation has hardly been reported in medical literature.

121 ning on regional ventricular performance has hardly been studied.

122 nction and clinical expression of asthma has hardly been studied.

123 precursors of free decisions to inhibit have hardly been studied.

124 , its influence upon respiratory control has hardly been studied.

125 ing levels of these molecules, however, have hardly been studied.

126 impact of long noncoding RNAs (lncRNAs) has hardly been studied.

127 is goal are well advanced for DNA, they have hardly begun for RNA.

128 aspect of non-redundant subsets is that they hardly benefit from the rapid pace of protein structure

129 ithms based on protein sequence features are hardly better than random in predicting PPIs.

130 nds and transfers phosphatidic acid (PA) but hardly binds phosphatidylcholine.

131 d) bioaccessibility of carotenoids including hardly bioaccessible epoxycarotenoids, finding unaltered

132 m spin Hall and original quantum Hall states hardly both co-exist in a single material due to their c

133 ral resolution as small as one second, which hardly can be met by conventional analytical methods for

134 The mutant hardly catalyzes transport, but binds galactosides from

135 otor oils, gasoline, car wax and hand cream) hardly cause confusion in alerting the presence of an ex

136 such as disorder and aggregation propensity, hardly change.

137 r men aged 30-34 years, mortality rates have hardly changed (reduction of 3.7%, 95% UI 2.7-4.9).

138 alignant brain tumors, and the prognosis has hardly changed in the past 20 years, with only 30% of pa

139 nm, whereas those of IL-2Ralpha/IL-15Ralpha hardly changed.

140 nterventricular dyssynchrony, whereas LV EDV hardly changed.

141 ffects significantly the number of sites but hardly changes the association constant.

142 ever, the 60 meV lowered LUMO level of NCBDT hardly changes the Voc level, and the elevation of the N

143 bright)CXCR4(+) cells reside in bone marrow, hardly circulate in healthy donors and are absent in cor

144 on is also an autoantigen, something that is hardly coincidental.

145 perception benefits from "local hotspots" is hardly compatible with the fact that neural representati

146 ult from common variants of small effect and hardly concentrated in candidate categories, or an infla

147 becomes very unlikely as an origin, which is hardly consistent with the most favored ejection mechani

148 so showed that although the copper ion alone hardly contributes to affinity, substrate binding is enh

149 While this minor species hardly contributes to the measured average solution beha

150 tants encoding Ag that can either be well or hardly cross-presented, mainly CD8(+) T cells specific f

151 Since L. pneumophila cells are hardly culturable from these pellets, detection methods

152 Phenanthrene hardly degraded on Cu-montmorillonite.

153 tic extracts, however, exit from mitosis was hardly delayed, showing that other phosphatase(s) are al

154 en approached because the total killing rate hardly depends on the breadth of the immune response.

155 relative stereochemistry in oligosilanes are hardly described.

156 Furthermore, experiments can hardly detect the nucleation and early stages of growth

157 Because low stability G-quadruplexes are hardly detectable by mass spectrometry, we optimized sol

158 t the surface (>0.8 V) is demonstrated to be hardly detectable by XPS measurements because of the sho

159 With the optimized protocol, a hardly detectable fluorescent signal was obtained after

160 ormal colon epithelium, while expression was hardly detectable in colon cancer tissues.

161 for supporting cardiac contractility, but is hardly detectable in cultured cardiomyocytes and is diff

162 ding glioblastoma stem/initiating cells, but hardly detectable in non-neoplastic astrocytes, neural s

163 In contrast Kv1.4 and 1.6, which were hardly detectable in the naive state, showed increased e

164 ise, NELF and DSIF prior to stimulation were hardly detectable on ISGs, which were strongly recruited

165 n been studied by examining EEG responses to hardly detectable stimuli.

166 spective knock-out mutant, plastoquinone was hardly detectable, and the mutant required 4-hydroxybenz

167 nts containing Ty-2 resistance the virus was hardly detectable, but the siRNA profile resembled the o

168 human primary monocytes, the protein remains hardly detectable.

169 nd Caco-2 cells, but the core3 structure was hardly detectable.

170 ffect on liver lysates, where expression was hardly detectable.

171 s a "silent killer", kidney disease is often hardly detected at an early stage but can cause lethal k

172 ntermediate affinity state of alphaLbeta2 is hardly detected by conventional adhesion assays, but rob

173 actively transcribed, while transcripts were hardly detected from genes with extensive crosslinking i

174 Although ANCCA is hardly detected in normal human prostate tissue, high le

175 le-single nucleotide polymorphism (SNP) GWAS hardly detected significant associations at high-stringe

176 Thus, intracellular Ca2+ mobilization was hardly detected under the condition that LFA-1 played th

177 Persistent overweight hardly differed from a persistent healthy weight.

178 n the field are commonly associated and thus hardly discernable.

179 ive and fast protein quantification, but can hardly discriminate between protein variants.

180 We found that most participants could hardly discriminate between TOMs, although they easily d

181 lecular methods (e.g. DNA- or protein-based) hardly distinguish between dead innocuous cells and thei

182 andard population genetics inference methods hardly distinguish it from drift and many species cannot

183 ties to interbreed in a large area, but they hardly do so.

184 smaller pi-conjugation structure, which can hardly enforce the pi-pi stacking assembly.

185 nteractions with endogenous transporters and hardly enter cells.

186 y reduced proliferation rate and competence, hardly enter into the S phase, and undergo accelerated s

187 While these subtle variations are hardly ever accessible through bulk or ensemble averaged

188 cluster of low-risk HPV infections that were hardly ever associated with high-grade CIN and, almost e

189 ACNES is hardly ever considered in the differential diagnosis of

190 Genetic alterations of this gene are hardly ever observed in sporadic breast cancer, while in

191 Walking or bicycling (>60 minutes/day vs. hardly ever; HR, 0.88; 95% CI, 0.82-0.95) and work or oc

192 ccurred to me" (yes, quite often; sometimes; hardly ever; never).

193 an average survival of glioblastoma patients hardly exceeds 12 months.

194 ower, and NIH budgets (the foregoing list is hardly exhaustive).Recently, a piece of legislation was

195 creasing the doping level to 24%, the device hardly exhibits any resistive switching.

196 Ten years ago, these phrases hardly existed.

197 e Se speciation in deficient environments is hardly existent.

198 Other maternal factors hardly explained this ethnic disparity in birth weight o

199 An attractive yet hardly explored feature of hydrophilic interaction liqui

200 In humans, it is hardly explored whether these CM consequences can be tra

201 e transcription, even though these genes are hardly expressed in PSCs.

202 is a transmembrane protein that is absent or hardly expressed on normal hematopoietic stem cells, but

203 hese gene deficits via genome engineering is hardly feasible.

204 urrent gold standard of toxicity testing, is hardly feasible.

205 h of ultrasonic treatment, viable cells were hardly found.

206 ng volatilization in planetary rocks, but is hardly fractionated during terrestrial igneous processes

207 However, these methods can hardly fulfill the exponentially-growing resource requir

208 utcome of PTRMS patients is excellent and is hardly improvable.

209 ough associated with AD, these genes jointly hardly improve prediction of AD.

210 h GBM is under 10 months and the outlook has hardly improved over the past 20 years.

211 erived CD4(+) cells and CTCL cell lines, but hardly in T cells from healthy donors.

212 Yet migration is hardly included in commonly used IAMs.

213 exposed Art v 1, were hypoallergenic as they hardly induced degranulation of rat basophil leukemia ce

214 However, alum hardly induces T helper 1 (Th1) immune responses that ar

215 The HER2 distribution was hardly influenced by trastuzumab for the HCC1954 cells.

216 ed liver function in both age groups, but it hardly influenced the other tests.

217 They hardly inhibited PR3 bound to the surface of stimulated

218 re trapped by interfacial V(o) on TiO(2) and hardly interact with perimeter O(2) molecules.

219 In contrast, the W972R mutant hardly interacts with E2.

220 for humans and nonsessile animals, they are hardly intuitive for simple, lifeless, homogeneous objec

221 icacy of prebiotics is an area that has been hardly investigated.

222 r constituents upon environmental release is hardly known.

223 s and their structural changes over time are hardly known.

224 of land-use on total local biodiversity are hardly known.

225 lling tools to the powder is significant and hardly measurable for processes in planetary ball mills.

226 results of material flow analyses (MFAs) can hardly meet.

227 n murine life) and clinical course make them hardly models of their human counterparts.

228 observers combine parts efficiently, needing hardly more energy to identify an object with more parts

229 s there were a few significant findings, but hardly more than would be expected in this large experim

230 We hardly notice our eye blinks, yet an externally generate

231 Stabilising effects of pectins were hardly noticeable when evaluating total phenolic content

232 lthough the issues raised in the report were hardly novel, they gave a new and powerful voice to the

233 n-lytic bacterium-phage interaction which is hardly observable using conventional microscopic methods

234 intermolecular disulfide bridging, which was hardly observed when C-mannosylated.

235 hed 40% in 12 h, whereas (13)C incorporation hardly occurred under darkness.

236 is extremely prevalent in human elderly, it hardly occurs in non-primate mammals and even non-human-

237 t of nanotechnology on analytical science is hardly overlooked.

238 7A Fab', we showed that the protein fragment hardly penetrated into the lungs following subcutaneous

239 ential of the Fc donors in one hemisphere is hardly perturbed by the push-pull acceptors in the other

240 It was hardly possible to begin to answer this question at that

241 In practice, however, it is hardly possible to measure fitness for all genotypes in

242 Achieving this goal by galvanic exchange is hardly predictable and often results in major structural

243 Because migraine attacks are hardly predictable and thereby the premonitory phase is

244 ical outcomes for bitopic molecules that are hardly predictable from the properties of individual ort

245 geting makes the success of these approaches hardly predictable.

246 of cooked cowpeas whereas flavan-3-ols were hardly present except catechin glucoside.

247 Clinically used Interceed film can hardly prevent the adhesion in any of these models.

248 ingly, irradiation with traveling microwaves hardly produced heat, but increased the organic radicals

249 P11- or CASP1/11-deficient mice were not, or hardly, protected against a lethal TNF or CLP challenge.

250 on relative quantitative analysis, which can hardly provide direct comparative glycomic quantitation

251 due to its intrinsic cell-based nature, can hardly provide insights into the molecular targets for s

252 neglected diseases may be neglected but are hardly rare, affecting hundreds of millions of people ar

253 mmonly used for protein solubilisation could hardly re-dissolve the precipitated proteins in the pell

254 gly electron rich aryl chlorides, previously hardly reactive, could be efficiently coupled with aliph

255 nerable to sulfur corrosion (tarnishing) but hardly reacts with O(2) , despite the thermodynamic pred

256 this clade, but most Orbiculariae make webs hardly recognizable as orbs.

257 pyrene emission, induced by the quencher, is hardly reflected in the pyrene excimer emission.

258 Intraoperative recognition of hardly removable old hemorrhagic clot as self-blockage s

259 Although equine and canine viruses hardly replicated in the respiratory systems of pigs, av

260 However, piezoelectricity is hardly reported in monoelemental materials owing to thei

261 e sluggish water oxidation reaction has been hardly reported to be efficient and selective in CO(2) c

262 hese conditions, the extent of oxidation was hardly reproducible, and led to various types of oxidize

263 al' speciation), a Darwinian hypothesis that hardly requires justification.

264 ase in AWP, while those in the lowland would hardly respond (on average, -3% when mean annual tempera

265 can modulate DeltamuH(+), their effects are hardly reversible, and lack cellular specificity and spa

266 ium marinum Although this substrate pair was hardly secreted when homologously expressed, it was secr

267 However, this definition hardly seems fitting for the millions of people who suff

268 the oscillatory magnetoresistive response is hardly sensitive to theta.

269 6-19 IgG3 mAb are poorly galactosylated and hardly sialylated, possibly contributing to the pathogen

270 essures up to 1 kbar are reached, G-actin is hardly stable.

271 ling hot water: drops on nanometric features hardly stick owing to the miniaturization of water bridg

272 t demand since treatment after the onset can hardly stop or reverse the disease progress.

273 Designing such processes is hardly straightforward, however, especially when the des

274 ut the binding was shown to be weak and thus hardly studied.

275 including those causing enteric disease, are hardly studied.

276 as much as these major binding residues seem hardly sufficient to explain the strong binding of RLF t

277 Finally, with some cell lines, DS can hardly support even transient plasmid replication withou

278 postsurgery radiotherapy or chemotherapy can hardly support the functional recovery of the tongue-par

279 Compound 16 (10 muM) hardly suppressed cyclooxygenase (COX)-1/2 activities, f

280 and large a 3-dimensional phenomenon, it is hardly surprising that 3D imaging has had a significant

281 ng the rate of cardiac repolarization, it is hardly surprising that essentially every aspect of K(+)

282 It is hardly surprising that matching genetic models to comput

283 Thus, it is hardly surprising that virus-specific CD8(+) T cells rec

284 It is hardly surprising, therefore, that the in vivo activity

285 is conceptual ambiguity and heterogeneity is hardly surprising.

286 higher eukaryotes such as plants and mammals hardly survive a deuterium content of >30%, many microor

287 g cancer, although the long-term survival is hardly sustainable.

288 We argue that moral decisions are hardly to be left to a computer.

289 drastically decreased cell signals and it is hardly to predict which layout changes lead to a substan

290 ld be explained by MARC1 expression that was hardly unaffected by KO, and we found no evidence of sig

291 uced nonlinear optical (NLO) applications is hardly understood and demands prompt attention.

292 The idea was at first hardly understood by the scientific community because it

293 why cells need EF2 to contain diphthamide is hardly understood.

294 llenge to WO3, the relevant mechanisms being hardly understood.

295 e its power to explain binding events, it is hardly used in protein/ligand design to modulate molecul

296 Antioxidant activity hardly varied in the assays with quinoxyfen, fluquincona

297 of EAGB (and thus EAGB(i) ) across quadrats hardly varied over 30 years (and seven censuses).

298 ve large variation within some orbits and to hardly vary within others.

299 While the differences are hardly visible in the free energy, they involve striking

300 ich was invisible on computed tomography and hardly visible on MRI, i.e. as countless, tiny, slightly