ライフサイエンスコーパス: head-to-head

1 type locus contains a pair of genes arranged head-to-head.

2 sions where duplicated segments are arranged head-to-head.

3 RNA polymerase II (RNAPII) molecules collide head-to-head.

4 re (5 Atkins, 4 WW, and 1 South Beach) and 2 head-to-head (1 of Atkins, WW, and Zone, and 1 of Atkins

5 ples, 30-43% yield), resulting either from a head-to-head [2 + 2]-photodimerization or from a twofold

6 ediates, i.e. 3- and 4-peptides that line up head to head across the entire APP transmembrane sequenc

7 omes within the primary outcome, considering head-to-head active comparator trials, increasing the di

8 In a direct head-to-head against open-label Restasis, CyclASol was f

9 ly motile cells that display no tendency for head-to-head agglutination and lack affinity to the ovid

10 Head-to-head analyses of relapse and disability outcomes

11 ollowing communication between sites in both head-to-head and head-to-tail orientations, we could sho

12 The nearly exclusive products from head-to-head and head-to-tail oriented "non-homologous"

13 bundant charged domain walls with conducting head-to-head and insulating tail-to-tail configurations,

14 Head-to-head and tail-to-tail magnetic domain walls in n

15 AR dimerization follows a unique head-to-head and tail-to-tail manner.

16 These 'head-to-head' and 'tail-to-tail' Bloch point configurati

17 e expression of a previously uncharacterized head-to-head antisense transcript, both transcripts bein

18 ted enhancement of gene expression involving head-to-head antisense transcription at a cancer-related

19 Twin CMG complexes are assembled head-to-head around duplex DNA at eukaryotic origins of

20 A single crystal X-ray structure shows a head-to-head arrangement of porphyrins that explains bot

21 low gates in each hemichannel and the serial head-to-head arrangement of these gates in the intercell

22 The gene lies in a head-to-head arrangement with TFPT, a poorly characteriz

23 omains oriented in a unique disulfide-linked head-to-head arrangement.

24 in the Cph1 dimer are aligned in a parallel 'head-to-head' arrangement and that photoconversion betwe

25 We performed a head to head assessment of FR104 (n=5), a selective pegy

26 he cytoplasms of two cells and are formed by head to head association of two hemichannels, one from e

27 To test this hypothesis, we compared on a head-to-head basis the diagnostic performance of (64)Cu-

28 a larger prospective design, to compare on a head-to-head basis the performance of (64)Cu-DOTATATE an

29 From a prospective study, we compared, on a head-to-head basis, sets of (64)Cu-DOTATATE PET/CT image

30 and (68)Ga-DOTATOC PET/CT and compared on a head-to-head basis.

31 and (68)Ga-DOTATOC PET/CT and compared on a head-to-head basis.

32 lity complex molecules (pMHCs) in "vertical" head-to-head binding.

33 Head-to-head biodistribution experiments comparing SA-bi

34 and healthy control subjects were evaluated head-to-head by the TST, QuantiFERON-TB-Gold in-tube tes

35 ly more stable than the corresponding linear head-to-head cation.

36 Head-to-head clinical trials are required to confirm the

37 Results from head-to-head clinical trials that compared direct oral a

38 CER methods in RA include head-to-head clinical trials, advanced techniques to sum

39 relative efficacy has not been determined in head-to-head clinical trials.

40 during duplex translocation, predicting that head-to-head CMGs at an origin exert force on opposite s

41 Thus, upon assembly of head-to-head CMGs that encircle double-stranded DNA at t

42 RNAPII stops but does not dissociate upon head-to-head collision in vitro, suggesting that opposin

43 Head-to-head collision in vivo also results in RNAPII st

44 e type 1 cubane formation pathway via direct head-to-head combination of two [Co(2)(dpy-C{OH}O)(2)(OA

45 This study provides the first head-to-head comparative analysis of leading antigens us

46 However, there is a lack of head-to-head comparative effectiveness studies comparing

47 This controlled clinical head-to-head comparative study revealed PET to exhibit t

48 As head-to-head comparative trials between P2Y12-receptor a

49 We head-to-head compared the accuracy of these systems in p

50 In our head to head comparison, SMART and CLARK had similar acc

51 In head-to-head comparison (using satellite data from 2003

52 This head-to-head comparison aimed to identify genes required

53 Head-to-head comparison and validation of these tracer c

54 This was a head-to-head comparison between (68)Ga-labeled prostate-

55 Herein, we report a head-to-head comparison between 5 nm renal clearable and

56 Head-to-head comparison between ferret and human antiser

57 The head-to-head comparison between the two point-of-care te

58 To the best of our knowledge, no prospective head-to-head comparison between these tests has been don

59 ools, Kattan nomogram and CAPRA-S score in a head-to-head comparison for predicting risk of recurrenc

60 Head-to-head comparison in human lung cells by NGS revea

61 d safety of ticagrelor versus prasugrel in a head-to-head comparison in patients with ST-segment-elev

62 wo clinical trials have been published and a head-to-head comparison is lacking to date.

63 Here, a head-to-head comparison is made between mechanisms based

64 etection of TF, we performed a prospective a head-to-head comparison of (18)F-FDG and (18)F-FLT in pa

65 Methods: This was a post hoc head-to-head comparison of (68)Ga-DOTATATE-based and (11

66 The goal of this study was to make a head-to-head comparison of 2 common forms of multidiscip

67 igate some of the challenges revealed in our head-to-head comparison of aptamer binding assays, we fu

68 The first head-to-head comparison of clinical features in these co

69 e goal of this study was to conduct a direct head-to-head comparison of different stem cell types in

70 Head-to-head comparison of empty and genome-containing p

71 Head-to-head comparison of fibrosis biomarkers ST2 and G

72 We performed a head-to-head comparison of five different adjuvants Alum

73 the clinical translatability of the model by head-to-head comparison of liver biopsy histological and

74 Interestingly, a head-to-head comparison of mice with deletion of Adora2b

75 This head-to-head comparison of prasugrel and ticagrelor does

76 INTERPRETATION: This first head-to-head comparison of quetiapine-ER versus aripipra

77 This first head-to-head comparison of recombinant versus inactivate

78 Based on these results, a head-to-head comparison of rivaroxaban with long-term lo

79 fore, this study was undertaken as the first head-to-head comparison of subcutaneous (SC) abatacept a

80 A head-to-head comparison of the antibody responses induce

81 No randomized head-to-head comparison of the efficacy and safety of ti

82 Here we report a head-to-head comparison of the immunogenicity and reacto

83 nd (18)F-FES PET/CT imaging, which allowed a head-to-head comparison of these 2 PET tracers.

84 of rNMP sequencing experiments and enable a head-to-head comparison of these experiments.

85 No head-to-head comparison of these regimens has been condu

86 We performed a head-to-head comparison of these technologies.

87 The present study is a large, randomized head-to-head comparison of these treatments on outcomes

88 The phase 3 ENDEAVOR trial was a head-to-head comparison of two proteasome inhibitors in

89 By conducting head-to-head comparison on in vivo transport and interac

90 Head-to-head comparison showed that (89)Zr-transferrin t

91 Utilizing FiNad, we performed a head-to-head comparison study of common NAD(+) precursor

92 A blind, head-to-head comparison study of SpinDx versus the gold-

93 A prospective head-to-head comparison to assess the effects of the var

94 rtussis detection, although there is limited head-to-head comparison to evaluating the PCR yield from

95 ative of the tumor as a whole as assessed by head-to-head comparison to single cell suspensions of di

96 A head-to-head comparison was performed of the effects of

97 The procedures developed for this head-to-head comparison will be useful for future evalua

98 pients over a period of 42 d and performed a head-to-head comparison with a conventional B cell ELISp

99 As proof-of-principle, we performed a head-to-head comparison with other available tools on se

100 attractive new vaccine candidate that merits head-to-head comparison with other modalities of vaccine

101 egression analysis was used, combined with a head-to-head comparison, for follow-up at 12, 24, and 60

102 In a head-to-head comparison, however, the B. burgdorferi Del

103 Strikingly, in a head-to-head comparison, oncogenic BRAF(V600E) elicited

104 fluorescence reporter mouse and performing a head-to-head comparison, we demonstrate more stringent m

105 Through a head-to-head comparison, we find that ICE libraries yiel

106 luoroethyl)tyrosine ([(18)F]FET) tracer in a head-to-head comparison.

107 ickening with, however, scarce data on their head-to-head comparison.

108 Though there are no head to head comparisons with other pharmacological agen

109 In head-to-head comparisons among children with both GA and

110 Head-to-head comparisons among NOACs were not available.

111 To date, head-to-head comparisons are missing.

112 However, no head-to-head comparisons between MRE and ARFI for diagno

113 cs are the best options in HE treatment, but head-to-head comparisons between these drugs are scarce.

114 Head-to-head comparisons between various medications and

115 Because head-to-head comparisons of AEDs (used in the European U

116 Direct head-to-head comparisons of biologicals are lacking; the

117 Head-to-head comparisons of conventional influenza vacci

118 This work carries out head-to-head comparisons of currently available NIR-II p

119 n to inactivate platelet COX-1 will confound head-to-head comparisons of distinct NSAIDs in ongoing c

120 gies during transitions in care) rather than head-to-head comparisons of medications.

121 There were no head-to-head comparisons of NOACs and limited data on ha

122 Hence, there is a need for head-to-head comparisons of promising TSPO PET tracers a

123 long-term follow-up data are available from head-to-head comparisons of second-generation drug-eluti

124 Despite the rather limited number of head-to-head comparisons of sstr antagonists and agonist

125 We performed head-to-head comparisons of the cellular and humoral imm

126 Head-to-head comparisons of the relative performances of

127 We tested this assumption by performing head-to-head comparisons of the requirements for each co

128 upranational reference laboratories to allow head-to-head comparisons of two new tests, Hain Genotype

129 The number of head-to-head comparisons was limited.

130 Head-to-head comparisons were sparse, and network meta-a

131 All the head-to-head comparisons were supported by very-low-qual

132 placebo-controlled studies predominate over head-to-head comparisons, although the latter would be m

133 Few trials, no head-to-head comparisons, and inadequate follow-up in ma

134 Sensitivity and specificity estimates, head-to-head comparisons, measures of agreement, and lat

135 trial results to real-world settings include head-to-head comparisons, some that incorporate noninfer

136 ect evidence available from randomized blind head-to-head comparisons.

137 ety data, possible publication bias, and few head-to-head comparisons.

138 ed with previously validated methods through head-to-head comparisons.

139 nd outcome measurement were heterogenous for head-to-head comparisons.

140 ensional cell culture has yet to be shown in head-to-head-comparisons.

141 Head-to-head competition assays on agar plates indicate

142 ss differences were identified using ex vivo head-to-head competition assays.

143 A head-to-head competition of the two pools starting from

144 First, by direct head-to-head competition, nuclear-localized SerRS blocks

145 ids and outcompeting the wild-type genome in head-to-head competition.

146 ge two-helical assemblies that associate via head-to-head contacts between coiled-coil middle domains

147 the majority of molecules are dimeric with a head-to-head contour distance of approximately 50 nm.

148 nts for adults with atrial fibrillation, but head-to-head data comparing their safety and effectivene

149 s from Ireland, Spain and the UK, as well as head-to-head data comparing this procedure with surgical

150 e furan backbone is almost unaffected by the head-to-head defect which is known to cause considerable

151 Both kinases reveal a head to head dimer with one major dimeric interface thro

152 gen-binding sites of these antibodies form a head-to-head dimer and cooperatively recognize the antig

153 The PhyB PSM crystallized as a head-to-head dimer with strong structural homology to it

154 lel beta-helix, antiparallel beta-helix, and head-to-head dimer.

155 In the structure, RctB adopts a head-to-head dimeric configuration that likely reflects

156 c molecular dynamics simulation study of AmB head-to-head dimerization in a phospholipid bilayer, a p

157 2-dichloroenynes makes the gold(I)-catalyzed head-to-head dimerization of chloroarylacetylenes an att

158 um chemical methods and experiments that the head-to-head dimerization of chloroarylacetylenes can be

159 In particular, "head-to-head" dimerization occurs when the intrinsically

160 Only a head-to-head direct comparison of the different new OACs

161 erent treatments, but in the absence of such head-to-head direct comparisons, another alternative to

162 A "head-to-head" direct comparison of drugs is the standard

163 The head-to-head domain boundaries exhibit high conductance,

164 Intriguingly, the vortex state arises at head-to-head domain boundaries in ferroelectric a(1) /a(

165 ferroelectric BaTiO3 tunnel barrier, where a head-to-head domain wall is constrained.

166 ias that leads to energetically unfavourable head-to-head domain walls in as-grown epitaxial PbZr(0.2

167 loads two hexameric MCM helicases to form a head-to-head double hexamer around DNA(1,2).

168 two heterohexameric Mcm2-7 complexes into a head-to-head double hexamer that facilitates bidirection

169 Minichromosome Maintenance (MCM) proteins as head-to-head double hexamers during DNA replication orig

170 romyces cerevisiae and other eukaryotes as a head-to-head double-hexamer around origin DNA.

171 of the Mcm2-7 replicative helicase to form a head-to-head double-hexamer, ensuring activated helicase

172 which corresponds to the gold complex of the head-to-head E-enyne.

173 The formation of the corresponding linear head-to-head enynes has not been reported yet.

174 We conducted a head-to-head evaluation of ten point-of-care-style later

175 In head-to-head experiments with PAC-1, pharmacokinetic eva

176 an asymmetric tunnel-fold homodecamer of two head-to-head facing pentameric subunits, harboring 10 ac

177 study compared these approaches in a direct head-to-head fashion in a contemporary population.

178 occupied by Hsp47 molecules, which bind in a head-to-head fashion, thus making extensive contacts wit

179 nhibitors (ARNI), have not been studied in a head-to-head fashion.

180 andomized comparison of multiple agents in a head-to-head fashion.

181 llizes as a C3-symmetric dimer in an unusual head-to-head fashion.

182 AlO3 on SrTiO3 substrate is accompanied with head-to-head ferroelectric-like polarizations across the

183 II was organized into laterally associated, head-to-head filament chains highly reminiscent of mamma

184 te by measurements in which two RNAs compete head-to-head for a limited amount of CP.

185 We compared MRE versus ARFI head-to-head for diagnosing fibrosis in well-characteriz

186 ST2 and galectin-3 (Gal-3) were compared head-to-head for long-term risk stratification in an amb

187 as a cis regulatory element separating close head-to-head genes with different transcription regulati

188 A distribution of head-to-head, head-to-tail, and tail-to-tail regiochemis

189 Idas in complex with Geminin showed a tight head-to-head heterodimeric coiled-coil.

190 tion complex, including the formation of two head-to-head hexameric helicases around the replication

191 Note that head-to-head (HH) linkages have traditionally been avoid

192 he glycine-rich tail is sufficient to form a head-to-head homodimer primarily via its N-terminal doma

193 Head-to-head hybridization of these transcripts blocks s

194 protium heroin (H(Ac)) haptens were compared head to head in an inclusive vaccine study.

195 inary validation, but few have been compared head to head in independent centers and in different sta

196 PCV10 and PCV13 were studied head-to-head in a randomized controlled trial in Papua N

197 d mammalian expression systems and completed head-to-head in vitro and in vivo evaluations.

198 In head-to-head infections at fixed multiplicities of infec

199 Moreover, we show that the head-to-head juxtaposition of the Mcm2-7 double hexamer

200 dgap (1.37-1.46 eV) polymers incorporating a head-to-head linkage containing 3-alkoxy-3'-alkyl-2,2'-b

201 The head-to-head linkage enables polymers with sufficient so

202 osome axes and span the width of the SC in a head-to-head manner, similar to the orientation of other

203 A head-to-head molecular assembly configuration of the NGF

204 Accordingly, we performed head-to-head molecular, antigenic, and immunogenic compa

205 We propose that head-to-head motors may generate energy that underlies i

206 tents (DES) have mostly been investigated in head-to-head non-inferiority trials against early-genera

207 thway which is initiated by the formation of head-to-head non-toxic dimers and hexamers en route to a

208 tegy was a 1 year, double-blind, phase 3b/4, head-to-head, non-inferiority, randomised controlled tri

209 The head-to-head NS1(172-352) dimer we observe in crystal la

210 otopic subcomponents, respectively, allows a head-to-head or head-to-tail double helix to be generate

211 The effect of target site orientation (head-to-head or head-to-tail) on the TPM behavior of syn

212 als are aligned to the ligand orbitals in a "head-to-head" or "side-to-head" fashion.

213 cent genes organized in a divergent fashion (head to head orientation) and separated by <1 kb.

214 t of Stx2e, one NbStx2e1 is interacting in a head-to-head orientation and directly competing with the

215 at CMGs that encircle double strand DNA in a head-to-head orientation melt the duplex in an Mcm10-dep

216 Closely apposed genes in a head-to-head orientation share the same upstream region

217 curs via rigid body docking of monomers in a head-to-head orientation to form kinetically trapped dim

218 When the sites are in head-to-head orientation, the knot products contain even

219 two Mcm2-7 helicases around origin DNA in a head-to-head orientation.

220 thylated DNA sequences in inversely repeated head-to-head orientations for efficient cleavage to occu

221 s harboring this intergenic sequence between head-to-head oriented green fluorescent protein and beta

222 cotranscribed with their parents and 3% with head-to-head oriented neighbors.

223 , we noted that AtClpB-C and AtCK2 genes are head-to-head oriented on chromosome 1 of the Arabidopsis

224 A-strip assay achieved comparable results in head-to-head performance tests with the qPCR reference,

225 Head-to-head PET/CT comparison of (124)I versus (89)Zr-d

226 The divergent depolarization fields of the head-to-head polarizations cast the interface into an el

227 lues for the mechanism and inhibition of the head-to-head prenyl transferases and should aid future d

228 phosphates from C(5) precursors; the epsilon head-to-head prenyl transferases that convert these diph

229 sis of a symmetrical monomer that provides a head-to-head pyridine building block for the preparation

230 The FIM12 study was a head-to-head randomised controlled trial in which 31,989

231 h IBS is unclear because there have been few head-to-head randomised controlled trials (RCTs).

232 work meta-analysis of placebo-controlled and head-to-head randomised controlled trials and compared 3

233 e therapy have been scarcely investigated in head-to-head randomised controlled trials, we aimed to c

234 ficacy is unclear because there have been no head-to-head randomised controlled trials.

235 Pragmatic head-to-head randomised trials would also provide direct

236 A lack of head-to-head randomized clinical trials (RCTs) comparing

237 The lack of head-to-head randomized controlled trials makes choosing

238 There are limited head-to-head randomized data on patient-related versus s

239 The first head-to-head randomized phase III comparative study betw

240 arison (MTC) meta-analysis uses both direct (head-to-head) randomized clinical trial (RCT) evidence a

241 However, the 2 head-to-head RCTs suggest that Atkins (range: -2.1 to -4

242 Head-to-head RCTs, providing the most robust evidence av

243 vage of two recognition sites in an inverted head-to-head repeat.

244 between a pair of target sites in inverted (head-to-head) repeat.

245 inherent long-term competitiveness in a HSC head-to-head secondary transplantation model.

246 the highest abundance of the single stranded head to head (SSHH) conformer.

247 allel double helix (PDH) and single-stranded head-to-head (SSHH) dimers were observed.

248 n the same layer allows a dyad to exchange a head-to-head stacking geometry (orange) for a head-to-ta

249 This was supported by meta-analysis of head-to-head studies (odds ratio, 9.617 [2.654-34.845])

250 However, to date, prospective head-to-head studies are lacking regarding the diagnosti

251 However, head-to-head studies are needed to assess the relative e

252 bviously, the ideal way to do this is to use head-to-head studies in CSU.

253 ences in diagnostic accuracy (moderate SOE); head-to-head studies of other biomarkers were limited.

254 hen, in a mouse asthma model by comparing in head-to-head studies, either IL-4 or IL-13 inhibition to

255 Comparative evidence is limited by few head-to-head studies.

256 The results are similar to those of previous head-to-head studies.

257 Based on statistical decision theory, our head-to-head study suggests that QuantiFERON-TB Gold In-

258 For this randomised, open-label, phase 3 head-to-head study, we enrolled patients (from centres i

259 If at least one 'head-to-head' study was found then a mixed treatment com

260 estigator blind thereafter), parallel-group, head-to-head superiority study (EXXELERATE), eligible pa

261 structure of ZIKV NS1172-352, which forms a head-to-head, symmetric dimer with a unique 14-stranded

262 ric intermediates; loci 1, 2, and 5 produced head-to-head/tail-to-tail concatemers; and locus 7 yield

263 We show that two monomers directly contact head-to-head through the FAT and kinase domains.

264 tiple immunogens and immunization strategies head-to-head to determine their impact on the quantity,

265 Their anti-parallel head-to-head-to-tail 'triplex' strand arrangement create

266 f the complex unexpectedly adopts a U-shaped head-to-head topology to form a crossover of each chain

267 Only 1 head-to-head trial met the inclusion criteria; both this

268 The aim of this head-to-head trial was to compare a standard bevacizumab

269 Scarce direct (head-to-head trial) evidence and population heterogeneit

270 In a head-to-head trial, we compared the safety and efficacy

271 en an area of speculation with no definitive head-to-head trial.

272 stic accuracy has not been compared in large head to head trials.

273 Additional studies including head-to-head trials and cost-effectiveness evaluation ar

274 s new members of a drug class are developed, head-to-head trials are an important strategy to guide p

275 Because additional head-to-head trials are unlikely, any further investigat

276 agents are effective treatments for UC, but head-to-head trials are warranted to establish the best

277 Although no head-to-head trials compare HCTZ with the uncommonly pre

278 To date, head-to-head trials comparing the efficacy and safety of

279 Large head-to-head trials evaluating long-term treatments are

280 We performed a systematic search of head-to-head trials for gaining objective reliable data

281 Head-to-head trials have shown CTDN's superiority in ant

282 Head-to-head trials in psoriatic arthritis are helpful i

283 with industry-sponsored trials, the lack of head-to-head trials of new effective treatments, the nee

284 Also, essential head-to-head trials of therapies for this complex progre

285 Head-to-head trials of these therapies in patients with

286 Until head-to-head trials or large-scale observational studies

287 Nine head-to-head trials showed greater pain reduction associ

288 Head-to-head trials to guide antipsychotic treatment cho

289 Head-to-head trials with novel systemic treatments are r

290 hese interventions have not been compared in head-to-head trials yet.

291 red any of these treatments with each other (head-to-head trials) or with placebo, in which the effic

292 placebo, to undertake a systematic review of head-to-head trials, and to compare the relative effecti

293 e of the entire photosensing module showed a head-to-head, twisted dimeric arrangement with bowed hel

294 alternative genome-wide CRISPR libraries in head-to-head validation.

295 e diastereoselectivity and regioselectivity (head-to-head versus head-to-tail adducts) is required fo

296 AcCYP51 dimerized head-to-head via N-termini swapping, resulting in format

297 Comparing the treatments head to head we derive conditions for choosing optimal t

298 ivatives between two reporter genes oriented head to head, we show that the TAL effector drives expre

299 The performance of the CoP was compared head to head with a platinum-based PEM under the same op

300 s efficacy and safety have not been compared head-to-head with the next-generation everolimus-eluting