ライフサイエンスコーパス: healthy aging

1 hich can reduce depression and contribute to healthy aging.

2 atures with mouse Taa cells increased during healthy aging.

3 is therefore a potential strategy to promote healthy aging.

4 orking memory capacity (WMC) associated with healthy aging.

5 omatic stem cells can be enhanced to promote healthy aging.

6 ples) were associated with increased odds of healthy aging.

7 id subclasses at midlife had greater odds of healthy aging.

8 strated the importance of kidney function in healthy aging.

9 oid intake in midlife with the prevalence of healthy aging.

10 age, 1517 women (11.0%) met our criteria for healthy aging.

11 of metformin-based interventions to promote healthy aging.

12 to 83%; P for trend = 0.002) greater odds of healthy aging.

13 Medin may become a novel approach to sustain healthy aging.

14 scribed frontotemporal pattern of changes in healthy aging.

15 king memory impairments in schizophrenia and healthy aging.

16 is of the conserved mechanisms that modulate healthy aging.

17 er effect on cardiorespiratory coupling than healthy aging.

18 this complex phenotype into subphenotypes of healthy aging.

19 er cognitive function, and lipid profiles of healthy aging.

20 other factors contributing to long life and healthy aging.

21 about alteration of a key neural circuit in healthy aging.

22 ne in episodic memory is a common feature of healthy aging.

23 t by eating well are important components of healthy aging.

24 modify the trajectory of disease to prolong healthy aging.

25 re enabling more precise characterization of healthy aging.

26 k by preventing premature aging or promoting healthy aging.

27 in function at rest is minimally affected by healthy aging.

28 of fat distribution and its association with healthy aging.

29 of circumstances that include but transcend healthy aging.

30 terventions to limit ferroptosis may promote healthy aging.

31 to whether cerebral perfusion declines with healthy aging.

32 ays to restore immune competence and promote healthy aging.

33 may reduce inflammation and possibly promote healthy aging.

34 diometabolic diseases and the improvement of healthy aging.

35 the role of OSER1 as a critical effector of healthy aging.

36 g brain development, with limited changes in healthy aging.

37 in aging processes and their deviations from healthy aging.

38 exposomes associate with poorer cognition in healthy aging.

39 en, mean age = 53 years (s.d. = 8)) achieved healthy aging.

40 brain disorders affect brain development or healthy aging.

41 noncommunicable diseases, optimally promote healthy aging.

42 ion is becoming a key strategy for promoting healthy aging.

43 elf-control might be an active ingredient in healthy aging.

44 w such technologies will shape the future of healthy aging.

45 80 years from the July 2023 National Poll on Healthy Aging.

46 rget for therapeutic intervention to promote healthy aging.

47 outcome measures of intervention effects on healthy aging.

48 r a shift to the 5' mature form of miRNAs in healthy aging.

49 I, 1.22-1.41) was positively associated with healthy aging.

50 ains, and declines especially steeply during healthy aging.

51 the diet may be a simple strategy to support healthy aging.

52 fer another window of opportunity to promote healthy aging.

53 this association may be important to promote healthy aging.

54 countries should be a priority for promoting healthy aging.

55 en the brain and gut that supports sleep and healthy aging.

56 Good oral health is essential for healthy aging.

57 ating neuronal protein synthesis can promote healthy aging.

58 intakes of flavonoid-rich foods may support healthy aging.

59 amined midlife protein intake in relation to healthy aging.

60 and dietary carbohydrate types in promoting healthy aging.

61 ellular responses that promote longevity and healthy aging.

62 w direction for therapies aimed at promoting healthy aging.

63 e quality may be an important determinant of healthy aging.

64 vaccine recommendations important to support healthy aging.

65 personality are associated with variation in healthy aging.

66 ved in maintaining metabolic homeostasis and healthy aging.

67 tered and inclusive interventions to support healthy aging.

68 h adverse future health outcomes and impedes healthy aging.

69 rdiac structure and function associated with healthy aging.

70 mmation and emerge as detrimental factors of healthy aging.

71 ty that can defy current universal models of healthy aging.

72 evel of physical function is a key aspect of healthy aging.

73 t life limits the risk of cancer and enables healthy aging.

74 sis is key to resisting stress and promoting healthy aging.

75 e neural processes change over the course of healthy aging.

76 nervous system might be targeted to promote healthy aging.

77 tal diseases but may also be associated with healthy aging.

78 ive solution to prevent cognitive decline in healthy aging.

79 tic advantages for mitochondrial disease and healthy aging.

80 cognitive networks that decline earliest in healthy aging.

81 chanisms of transtissue exercise benefits to healthy aging.

82 mostly of skeletal muscle, is important for healthy aging.

83 urodegenerative pathologies, and may promote healthy aging.

84 via conserved molecular pathways to promote healthy aging.

85 with a modest decrease in the likelihood of healthy aging.

86 ise as a new therapeutic paradigm to promote healthy aging.

87 pathways may be a novel strategy to promote healthy aging.

88 regulators locally rather than globally for healthy aging.

89 ally associated with tau tracer retention in healthy aging.

90 [4], to identify gut-microbial signatures of healthy aging.

91 , and mechanisms of action in the context of healthy aging.

92 cognitive decline is a genetic component of healthy aging.

93 d vegetables) may have a beneficial role for healthy aging.

94 ohydrate, or fat with plant protein (ORs for healthy aging: 1.22-1.58 for 3% energy replacement with

95 ies, the Canadian Community Health Survey on Healthy Aging (2008-2009), and the Quebec Longitudinal S

96 1) from the Canadian Community Health Survey-Healthy Aging (2008-2009).

97 ad a 24% increased likelihood of maintaining healthy aging (95% CI: 1.11, 1.38).

98 ted include a centenarian who was a model of healthy aging, a 92-year-old with dementia and clinicall

99 ining optimal skin function is essential for healthy aging across global populations; yet most resear

100 ntial hypermethylated upstream regulators of healthy aging (AL vs. YL), and of the effects of obesity

101 data from the December 2019 National Poll on Healthy Aging among a nationally representative househol

102 understand AM ontogeny in human lung during healthy aging and after transplant.

103 rapeutically targeting senescence to improve healthy aging and age-related disease, otherwise known a

104 Both healthy aging and Alzheimer's disease (AD) are character

105 gnatures of cognitive frailty in relation to healthy aging and Alzheimer's disease.

106 ntaining optimal lung function is useful for healthy aging and dementia prevention.

107 These case histories provide examples of how healthy aging and dementia relate to the degree of patho

108 who were enrolled in longitudinal studies of healthy aging and dementia.

109 , intrinsic evidence for such a link between healthy aging and development in brain structure remains

110 ide a framework to develop interventions for healthy aging and disease treatment.

111 n for understanding the relationship between healthy aging and disease, and for the development of ag

112 learning and memory and their alterations in healthy aging and diseases.

113 Aging in African Americans (STAR) and Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) stu

114 er maintenance of telomere length may confer healthy aging and exceptional longevity in humans.

115 illed with worthwhile activities may promote healthy aging and help sustain meaningful social relatio

116 se on cognitive and brain health outcomes in healthy aging and in individuals with or at risk for cog

117 al relaxation velocity declines as a part of healthy aging and is largely prognostically benign.

118 dherence was associated with greater odds of healthy aging and its domains.

119 across all main hematopoietic cell types in healthy aging and leukemia.

120 to understand the epigenetic contribution to healthy aging and longevity and the molecular basis of t

121 noncanonical Ahcy enzymes as determinants of healthy aging and longevity.

122 This regulatory axis is critical for healthy aging and may be a target for therapeutic modula

123 hain deficiencies caused by mtDNA decline in healthy aging and neurodegenerative disease.

124 tory animals can help to distinguish between healthy aging and pathological conditions that may contr

125 om the longitudinal Adult Children Study and Healthy Aging and Senile Dementia Study at the Knight Al

126 ein (HSP) 70 plays an important role in both healthy aging and the stress response to injury.

127 ctional Tfh may improve vaccine responses in healthy aging and those aging with HIV infection.

128 n midlife, is associated with higher odds of healthy aging and with several domains of positive healt

129 ences exist between the processes of normal "healthy" aging and pathologic age-related neurodegenerat

130 in the brains of T2DM patients compared with healthy aging, and inversely correlated with levels of b

131 outcomes, proper childhood development, and healthy aging, and it lowers the probability of developi

132 e development of novel drug targets for both healthy aging, and pathological aging such as Alzheimer'

133 rmalities in psychosis, their deviation from healthy aging, and the influence of sex on these measure

134 Parkinson's disease, whether it differs from healthy aging, and the mechanisms which drive these chan

135 ur consecutive sessions could improve vWM in healthy aging, and which are the neurophysiological and

136 will review the heterogeneity of HSCs in the healthy, aging, and diseased liver, focusing on cell-cel

137 initial formation of tangles and plaques in healthy aging appeared to be independent of each other.

138 ation of greater height with reduced odds of healthy aging appeared to be more evident among women wi

139 Healthy aging appears to primarily affect a frontal-stri

140 ves to optimize long-term health and promote healthy aging are based on the concept of functional fit

141 We use healthy aging as a proxy for better health and fitness,

142 nephron GFR remains relatively constant with healthy aging as does glomerular volume.

143 Extreme longevity is the paradigm of healthy aging as individuals who reached the extreme dec

144 ignificant change between young controls and healthy aging as measured by the GM volume and cortical

145 cation of genetic factors that contribute to healthy aging as well as the chronic conditions common i

146 rns and ultraprocessed food consumption with healthy aging, as assessed according to measures of cogn

147 h therapeutic interventions is essential for healthy aging, as the immune system plays a crucial role

148 patial pattern of hemodynamic sensitivity to healthy aging, as well as to test the role of hemodynami

149 s have been designed to advocate and fortify healthy aging at multiple levels.

150 ciplinary aging-friendly policies to promote healthy aging, basic biology and translational research

151 Centenarians are a model for healthy aging because they have reached the extreme limi

152 e production is beneficial for memory in the healthy aging brain, it might be detrimental in an Alzhe

153 Healthy aging can be promoted by enhanced metabolic fitn

154 The process of healthy aging can best be described by plotting the traj

155 Healthy aging can lead to impairments in learning that a

156 h unpublished data from 200 individuals of a healthy aging cohort (Erikson et al., Cell 165(4):1002-1

157 The effect on PC of healthy aging compared with aging with RFs or cardiovasc

158 rk (CON) exhibits reductions earliest during healthy aging, contributing to cognitive impairment.

159 range, 65-84 years; 12 men, 11 women) and 50 healthy aging control subjects (mean age, 73.1 years +/-

160 distensibility between patients with DM and healthy aging control subjects.

161 th in neurodegenerative disorders and in the healthy aging cortex, which exhibits elevated dendritic

162 lationship between higher heterozygosity and healthy aging could be explained by heterozygote advanta

163 otal of 3721 (7.6%) NHS participants met our healthy aging definition.

164 age, 48.5 [6.2] years), 3706 (7.8%) met our healthy aging definition.

165 Our results indicate that healthy aging does not significantly impair simple reinf

166 , we uncover a novel mutational signature in healthy aging endocrine cells.

167 e what methods can be used today to increase healthy aging, forestall the onset of these diseases, an

168 component of the World Health Organization's healthy aging framework.

169 rstand the role of dietary protein intake in healthy aging, greater efforts are needed to coordinate

170 Healthy aging has been associated with decreased special

171 Healthy aging has been shown to independently affect bot

172 iative emotional learning, but the impact of healthy aging has gone relatively unexplored.

173 resonance spectroscopy ((1)H-MRS) studies on healthy aging have reported inconsistent findings and ha

174 classical factors such as age and sex drive healthy aging, higher disparity-related factors and betw

175 Diet and exercise are determinants of healthy aging; however, the extent to which they affect

176 mpared to valence, little is known about how healthy aging impacts arousal-enhanced memory effects.

177 Healthy aging impacts visual information processing with

178 his cohort study used data from the Study of Healthy Aging in African Americans (STAR) and Kaiser Hea

179 udy analyzed baseline data from the Study of Healthy Aging in African Americans (STAR) cohort collect

180 Specific Needs of the Elderly Population for Healthy Aging in Europe (NU-AGE)] was carried out in old

181 Low protein diets are associated with healthy aging in humans, and dietary protein restriction

182 tion of age-related disease and promotion of healthy aging in humans, and the challenge of possible n

183 orm-specific sirtuin activation may have for healthy aging in humans.

184 and accessible intervention known to promote healthy aging in humans.

185 can result in fewer falls and contribute to healthy aging in India.

186 between-country variability could influence healthy aging in LAC countries.

187 plications for cardiovascular resilience and healthy aging in later life.

188 muscle mitochondrial respiration and promote healthy aging in metabolically stressed mammals.

189 Furthermore, NOB enhances healthy aging in mice fed with a high-fat diet (HF).

190 combining drugs shown to extend lifespan and healthy aging in mice would have greater impact than any

191 In the Healthy Aging in Neighborhoods of Diversity across the L

192 As part of the Healthy Aging in Neighborhoods of Diversity across the L

193 longitudinal cohort study used data from the Healthy Aging in Neighborhoods of Diversity Across the L

194 and White urban adults participating in the Healthy Aging in Neighborhoods of Diversity across the L

195 were conducted in 329 AA participants in the Healthy Aging in Neighborhoods of Diversity across the L

196 sical exercises has the potential to support healthy aging in older adults.

197 This study's objective was to investigate healthy aging in older French adults 5 years after a per

198 y of height (</=1.57 m), the OR of achieving healthy aging in the highest category (>/=1.70 m) was 0.

199 In contrast, healthy aging in three background strains exhibited the

200 out the brain in a nonhuman primate model of healthy aging in which the full complement of Alzheimer'

201 arding cardiovascular disease prevention and healthy aging in women.

202 spite changes in cognitive mechanisms due to healthy aging, including a general slowing in informatio

203 nted several additional phenotypes linked to healthy aging, including lower prevalence of cancer and

204 om 189 human postmortem brains, including 58 healthy aging individuals and 131 with a range of diseas

205 ells with age, but the changes that occur in healthy aging individuals is less clear.

206 ual decline in renal function occurs even in healthy aging individuals.

207 s, as well as limited access to tissues from healthy aging individuals.

208 ted prefrontal activity in humans, show that healthy aging induces functional alterations in the rewa

209 tudinal studies of subjects progressing from healthy aging into dementia will enable a detailed under

210 Healthy aging involves the interaction between genes, th

211 Healthy aging is a complex biological process with progr

212 Although healthy aging is accompanied by a general decline in mem

213 Healthy aging is accompanied by disruptions in the funct

214 Overall, our results suggest healthy aging is an overlapping but distinct phenotype f

215 Healthy aging is associated with a decline in basic perc

216 Healthy aging is associated with a higher mean GFR compa

217 A sedentary lifestyle during healthy aging is associated with decreased left ventricu

218 Healthy aging is associated with decreased neural select

219 ower in older age, but it is unknown whether healthy aging is associated with preserved rather than l

220 Our findings suggest that healthy aging is associated with system-level changes in

221 These findings suggest that healthy aging is associated with whole-brain connectome-

222 ect against age-related diseases and promote healthy aging is critical to public health.

223 onic disease prevention and the promotion of healthy aging is critical, especially because obesity, w

224 Active and healthy aging is in great demand in an aging society.

225 Additionally, healthy aging is not associated with a decreased rate of

226 longevity, usually focused on centenarians, healthy aging is not associated with known longevity var

227 This suggests that healthy aging is not associated with preserved GFR in ol

228 sability and normative functional beliefs of healthy aging is required in this population to inform i

229 Healthy aging is thought to reflect the combined influen

230 but whether they are associated with overall healthy aging is unknown.

231 Physical capability, a key component of healthy aging, is associated with cardiovascular and oth

232 can be used to benchmark a highly phenotyped healthy aging laboratory cohort into high- vs. low-risk

233 Healthy-aging LLFS presented 17 years delayed for CHD ag

234 aggression (antisocial personality disorder [healthy aging], mania/positive symptoms [early psychosis

235 d action of sensory and reward circuits, and healthy aging may be compromised when the expectations d

236 early psychosis, MDD), and somatic problems (healthy aging, MDD).

237 igated the associations of adult height with healthy aging measured by a full spectrum of health outc

238 sis and treatment of testosterone decline in healthy aging men and the associated clinical issues for

239 hese results suggest that the ability of the healthy aging motor cortex to reorganize in response to

240 l inhibition (avoidant personality disorder [healthy aging], negative symptoms [early psychosis]).

241 on our understanding of normal development, healthy aging, neurodevelopmental disorders, and adult-o

242 In a healthy aging normal population, choline/creatine and my

243 of this study was to evaluate the effect of healthy aging on brain incorporation of 11C-AA, before a

244 s have supported the preferential effects of healthy aging on frontal cortex, but reductions in other

245 as been done in this area and the effects of healthy aging on pupil responses to the different color

246 cereals were associated with higher odds of healthy aging (ORs ranging from 1.07; 95% CI, 1.03-1.11

247 ains were positively associated with odds of healthy aging (ORs ranging from 1.11; 95% CI, 1.07-1.15

248 bsequent increased likelihood of maintaining healthy aging over 6-8 years of follow-up.

249 ith a prudent dietary pattern in relation to healthy aging (P-interaction = 0.005), and among the ind

250 8% (95% CI: 6%, 11%) decrease in the odds of healthy aging per SD (0.062 m) increase in height.

251 n particle sizes are heritable and promote a healthy aging phenotype.

252 ay reduce risk of developing depression in a healthy aging population.

253 d factors associated with GCC thickness in a healthy aging population.

254 Direct comparison of healthy aging populations with schizophrenia and BD pati

255 NSAIDs) reduces the risk of developing AD in healthy aging populations.

256 upplementation was associated with a greater healthy aging probability among men (relative risk = 1.1

257 However, the roles of lncRNAs in aging/healthy aging processes remain largely unknown.

258 hypothesis that muscle insulin resistance in healthy aging promotes increased hepatic de novo lipogen

259 ting white matter microstructural changes in healthy aging provides essential context to clinical stu

260 ever, the role of ECM composition changes in healthy aging remains unclear.

261 g and contributes to emotional well-being in healthy aging remains unclear.

262 Healthy aging results in cardiac structural and electric

263 Normal healthy aging results in changes in Doppler indexes of d

264 Circulating PC levels do not decline with healthy aging; RF exposure at a younger age stimulates P

265 visual processing decline substantially with healthy aging, semantic knowledge is generally spared.

266 et scores, but its performance in predicting healthy aging shows comparable strength.

267 cures to devastating diseases and to foster healthy aging, shows the need to respect public sensibil

268 Centenarians are good models for healthy aging studies due to avoiding major chronic dise

269 Investigators in the Chicago Healthy Aging Study (CHAS) reexamined 1,395 surviving pa

270 The Walnuts And Healthy Aging study is a 2-center (Barcelona, Spain; Lom

271 sonance imaging was performed on 440 Chicago Healthy Aging Study participants in 2009 to 2011, whose

272 tched for working memory performance with 17 healthy aging subjects.

273 successfully separate patients with AD from healthy aging subjects.

274 matter loss in parietal regions is a part of healthy aging suggests that diminished rPPC grey matter

275 rences in gray matter reflect the effects of healthy aging that cannot be attributed to AD pathology,

276 With a long-term nutrition goal for healthy aging, the aim of this study was to compare the

277 With normal or healthy aging, the heart undergoes extensive vascular, c

278 In the RM model of healthy aging, the major regionally distributed effects

279 During healthy aging, the proportions of blood bronchoalveolar

280 his study provides rich data for research in healthy aging through inclusion of the non-carrier contr

281 s a critical event triggering the shift from healthy aging to Alzheimer disease (AD) through the over

282 -by-sex interaction in conversion risk (from healthy aging to mild cognitive impairment (MCI)/AD or f

283 ued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free

284 Healthy aging was assessed in 2007-2009 by using multipl

285 hy compared with usual aging as of age 70 y; healthy aging was based on survival to >/=70 y with main

286 Healthy aging was characterized by decreased static rest

287 Healthy aging was defined as being free from 11 major ch

288 Healthy aging was defined as being free of 11 major chro

289 "Healthy" aging was defined as survival to 70 years or ol

290 When the 4 components of healthy aging were analyzed separately, the AHEI-2010 an

291 y baseline (2006 or 2008), and components of healthy aging were assessed every 2 years, defined as: 1

292 I, 0.62-0.81) were inversely associated with healthy aging when comparing extreme quintiles.

293 , the atrophy pattern in PD was also seen in healthy aging, where it also correlated with the loss of

294 airy products were linked to greater odds of healthy aging, whereas higher intakes of trans fats, sod

295 GL was positively associated with healthy aging, which was attenuated by dietary fiber adj

296 Europe led in healthy aging, while Egypt and South Africa showed the g

297 eval processes, that are generally intact in healthy aging, will be particularly compromised in peopl

298 er understanding of the mechanisms that link healthy aging with lower fluid intelligence may suggest

299 icipants fulfilled our inclusion criteria of healthy aging, with normative values defined as the mean

300 literature, we found that GFR declines with healthy aging without any overt signs of compensation (s