ライフサイエンスコーパス: hearing

1 ty, muscle strength) or self-report (vision, hearing).

2 the cochlear fluids is essential for healthy hearing.

3 r cells (IHCs) are the primary receptors for hearing.

4 levels of HGF must be fine-tuned for normal hearing.

5 nding the functional roles of these cells in hearing.

6 anean rodents with, counterintuitively, poor hearing.

7 litates the vascular regression and improves hearing.

8 All but 1 patient had intact hearing.

9 cific through E10.5, but is not required for hearing.

10 y in the aging cochlea resulting in improved hearing.

11 ilarities and differences between vision and hearing.

12 precision, is important for many aspects of hearing.

13 future gene therapy approaches for restoring hearing.

14 al, thereby playing a pivotal role in normal hearing.

15 nd-caused loss in endocochlear potential and hearing.

16 ral sounds but to enhance the sensitivity of hearing.

17 tic stimuli is important for many aspects of hearing.

18 her sex), an avian animal model with complex hearing abilities similar to humans.

19 Many individuals with seemingly normal hearing abilities struggle to understand speech in noisy

20 rates of any neurologic, ophthalmologic, and hearing abnormalities were observed for PM (100%), DM (1

21 less than 1% (Iraqi: 0.3%; Afghan: 0.7%) had hearing abnormalities, and about 4% (Iraqi: 6.0% Afghan:

22 eech in such situations, even when wearing a hearing aid.

23 ter than for sound-localisation by bilateral hearing-aid users.

24 ineural HL (SNHL) with treatments limited to hearing aids and cochlear implants with no FDA-approved

25 hildren with hearing loss may include use of hearing aids, cochlear implants, bone anchored devices,

26 oding in emerging applications such as smart hearing aids.

27 nd other mammals, but nonmammals can recover hearing and balance after supporting cells regenerate re

28 Loss of sensory hair cells causes permanent hearing and balance deficits in humans and other mammals

29 STATEMENT Millions of people are affected by hearing and balance deficits that arise when loud sounds

30 king them a popular model for studying human hearing and balance disorders.

31 ecome an accessible model for studying human hearing and balance disorders.

32 Hearing and balance rely on the capacity of mechanically

33 ince a principle role for Tmc2a and Tmc2b in hearing and balance, respectively, whereas Tmc1 has lowe

34 m therian mammal that displays decoupling of hearing and chewing apparatuses and functions.

35 Evidence shows that hearing and chewing apparatuses have evolved in a modula

36 The tympanic membrane (TM) is critical for hearing and requires continuous clearing of cellular deb

37 e find little evidence that the evolution of hearing and sound producing organs increased diversifica

38 ecific and dynamic patterns of evolution for hearing and sound producing organs.

39 croevolutionary study to understand how both hearing and sound production evolved and affected divers

40 in various physiological processes, such as hearing and touch.

41 ssays to determine the reliance of zebrafish hearing and vestibular organs on Tmc proteins.

42 uid inertia is an important mechanism for BC hearing, and (2) SCD facilitates the flow of sound volum

43 called Whirlin, a scaffolding protein of the hearing apparatus.

44 Impaired lung function and impaired hearing are both criteria for workers' compensation clai

45 Users of hearing-assistive devices often struggle to locate and s

46 However, it is unclear how hearing associates with pathologies relevant to dementia

47 e majority of infants with cCMVi have normal hearing at birth, but are at risk of developing late-ons

48 osed to blocks in which they were at risk of hearing aversive screams at any time vs. blocks in which

49 d tumor control, preservation of serviceable hearing based on median pure tone averages (PTA), and pr

50 of ARHL - or the homeostatic maintenance of hearing before its breakdown - is missing.

51 ct that OHCs are required for high-frequency hearing but appear to be throttled by slow electromotili

52 loss (sARHL) cases and controls with normal hearing by whole-exome sequencing.

53 istinct ecological constraints on vision and hearing can explain this difference, if it is assumed th

54 Before the onset of hearing, cochlea-generated patterns of spontaneous spike

55 ng-impaired listeners and age-matched normal-hearing controls.

56 We provided missing speech and spatial hearing cues through haptic stimulation to augment the e

57 ound exposure sufficient to induce permanent hearing damage causes cochlear blood flow reduction, whi

58 ctions, these drugs often cause irreversible hearing damage.

59 f BBSOAS, including altered learning/memory, hearing defects, neonatal hypotonia and decreased hippoc

60 E STATEMENT As our society ages, age-related hearing deficits become ever more prevalent.

61 y regenerate once lost, leading to life-long hearing deficits.

62 ear's vulnerability to permanent balance and hearing deficits.SIGNIFICANCE STATEMENT Millions of peop

63 r findings disclose a logic of Tmc use where hearing depends on a complement of Tmc proteins beyond t

64 AN loss is widely expected to cause hearing difficulties in noise, known as "hidden hearing

65 gap" in animal models and "tinnitus inducing hearing difficulty" in human subjects.

66 s with tinnitus themselves, who often report hearing difficulty, especially in noise.

67 of next-generation clinical tests for hidden hearing disorders.

68 he development of treatments for age-related hearing disorders.

69 alizations, signals above the range of human hearing, during close-range social interactions.

70 neonates with cCMVI who underwent a complete hearing evaluation, 8 (12.9%; 95% CI, 6.7-23.4) had HL a

71 which, when preserved, provides an improved hearing experience in noisy environments.

72 r future work in SV-related hearing loss and hearing fluctuation.

73 ice could be effective for improving spatial hearing for a range of hearing-impaired listeners.

74 most widely used neuroprosthesis, recovering hearing for more than half a million severely-to-profoun

75 has successfully restored the perception of hearing for nearly 200 thousand profoundly deaf adults a

76 hemistry in the rat show that the peripheral hearing function and morphology of the organ of Corti ar

77 After adjusting for peripheral hearing function and performance on control tasks assess

78 irst time, we did a comparative study of the hearing function in an H-ABC patient and in this mutant

79 By analyzing hearing function, we found that there are no significant

80 critical for normal growth, development, and hearing function.

81 the immature cochlea, prior to the onset of hearing, hair cell loss stimulates neighboring supportin

82 cits in which are a major contributor to the hearing handicap in cochlear hearing loss.

83 For normal hearing, HGF levels must be fine-tuned as an excess or d

84 nificantly reduced contralateral to the most hearing-impaired ear compared with the ipsilateral side.

85 This process breaks down in hearing-impaired individuals and speech recognition devi

86 G responses with high accuracy in both older hearing-impaired listeners and age-matched normal-hearin

87 for improving spatial hearing for a range of hearing-impaired listeners.

88 Hundreds of thousands of profoundly hearing-impaired people perceive sounds through electric

89 enabled hundreds of thousands of profoundly hearing-impaired people to perceive sounds by electrical

90 e than half a million severely-to-profoundly hearing-impaired people.

91 improvement indices of 0.21 (P = 0.008) for hearing impairment and 0.26 (P < 0.001) for mobility imp

92 Hearing impairment may be a modifiable risk factor for d

93 It is currently unclear whether hearing impairment may impair the ability to use selecti

94 bjects (8%) and 0 of 13 control subjects had hearing impairment, as did 1 nonrandomized subject.

95 a reduced likelihood of functional recovery: hearing impairment, greater increase in postsurgical dis

96 hich were not included in prior risk models: hearing impairment, mobility impairment, weight loss, an

97 deficit, cerebral palsy, or severe visual or hearing impairment.

98 Moreover, our findings suggest that altered hearing in African mole-rats is adaptive, perhaps tailor

99 Patients often report particular difficulty hearing in busy environments; however, the core cognitiv

100 motors and are essential for high-frequency hearing in mammals.

101 identify the factors contributing to altered hearing in naked and the related Damaraland mole-rats an

102 A training method to improve speech hearing in noise has proven elusive, with most methods f

103 tility of using such games to improve speech hearing in noise.

104 Swim bladders in sciaenid fishes function in hearing in some and sound production in almost all speci

105 r competing talkers, despite having "normal" hearing in terms of audiometric thresholds.

106 ng multiple mutant alleles demonstrates that hearing in zebrafish is not dependent on Tmc1, nor is it

107 We highlight how the effect of hearing interventions on dementia depends on the specifi

108 Why certain perturbations affect BC hearing is also unclear.

109 Moreover, whether altered hearing is degenerate or adaptive to their unique lifest

110 gement outside of and during customary court hearings is analyzed.

111 speech understanding was measured in normal hearing listeners with or without tinnitus.

112 performance level to that achieved by normal-hearing listeners.

113 orns and children with metabolic diseases or hearing loss (106 participants total).

114 family with autosomal dominant non-syndromic hearing loss (ADNSHL).

115 ory cortex (PAC) in patients with asymmetric hearing loss (AHL).

116 Age-related hearing loss (ARHL) is a common problem for older adults

117 Age-related hearing loss (ARHL) is a very heterogeneous disease, res

118 Age-related hearing loss (ARHL) is associated with the loss of inner

119 Presbycusis, or age-related hearing loss (ARHL), is a major public health issue.

120 = 0.81) but weaker for clinically determined hearing loss (AUC = 0.60).

121 ouse strains with a different progression of hearing loss (C57BL/6J, C57BL/6NTac, C57BL/6NTac(Cdh23+)

122 mination was similar for ultrahigh-frequency hearing loss (frequencies >9000 Hz; AUC = 0.81) but weak

123 progressive sensorineural autosomal dominant hearing loss (HL) in 20 affected individuals from the DF

124 tomegalovirus infection (cCMVI) to permanent hearing loss (HL) in highly seropositive populations is

125 million people worldwide are diagnosed with hearing loss (HL).

126 ors and studied multiplex family age-related hearing loss (mARHL) and simplex/sporadic age-related he

127 Noise-induced hearing loss (NIHL) is a common health concern with sign

128 .73), chronic kidney disease (P = 0.09), and hearing loss (P = 0.31).

129 der listeners with age-related sensorineural hearing loss (presbycusis) often struggle to understand

130 oss (mARHL) and simplex/sporadic age-related hearing loss (sARHL) cases and controls with normal hear

131 making it the leading cause of sensorineural hearing loss (SNHL) in childhood.

132 compared with those caused by sensorineural hearing loss (SNHL).

133 d contribute to the different progression of hearing loss among mouse strains.

134 hypermobility, hypotonia, hyperelastic skin, hearing loss and aortic rupture.

135 hair cells in the ear, causing irreversible hearing loss and balance deficits for millions.

136 arch and novel interventions for alleviating hearing loss and cognitive decline.

137 al interest lies in the relationship between hearing loss and cognitive impairment.

138 e new insights for future work in SV-related hearing loss and hearing fluctuation.

139 , we can develop strategies for ameliorating hearing loss and improving speech recognition technology

140 CMV) infection is a major cause of childhood hearing loss and neurodevelopmental delay.

141 virus (cCMV) infection is a leading cause of hearing loss and neurological disabilities in children,

142 2, characterized by congenital sensorineural hearing loss and retinitis pigmentosa (RP), and also con

143 To determine the differential effect of hearing loss and tinnitus, both male and female particip

144 Early identification of hearing loss and understanding its etiology can assist w

145 s with non-syndromic bilateral sensorineural hearing loss and vestibular areflexia.

146 associated with high rates of post-operative hearing loss and vestibular dysfunction.

147 Hair cell death and consequent hearing loss are common results of treatment with ototox

148 Epidemiological studies identify midlife hearing loss as an independent risk factor for dementia,

149 ygous for del10 exhibit moderate-to-profound hearing loss at 4 weeks of age as measured by tone burst

150 The model predicting hearing loss at frequencies from 250 to 8000 Hz included

151 downstream targets, where the pathologies of hearing loss begin.

152 Without hearing rehabilitation, hearing loss can cause detrimental effects on speech, la

153 Hearing loss caused by the death of sensory hair cells o

154 Nhe6 knockout (KO) mice showed significant hearing loss compared to WT littermates.

155 lar types, that only lacked the more extreme hearing loss configurations observed in our patient coho

156 without the observed functional compensation hearing loss could be greater.

157 Yet, it is unclear whether a peripheral hearing loss degrades the attentional modulation of cort

158 Recently, hearing loss has been identified as potentially the most

159 Disabling hearing loss impacts ~466 million individuals worldwide

160 Hearing loss in children is common and by age 18 years,

161 When administered at nighttime, a mild hearing loss in GLAST KO mice was found but not at dayti

162 contributes to one third of all early-onset hearing loss in seropositive populations.

163 hs of age, were correlated with the level of hearing loss in the different mouse strains, being most

164 ral olivocochlea fibres, was correlated with hearing loss in the different mouse strains.

165 Age-related hearing loss is a progressive hearing loss involving environmental and genetic factors

166 Age-related hearing loss is a progressive hearing loss involving env

167 Hearing loss is a significant late effect among childhoo

168 dividuals without previous family history of hearing loss is challenging and has been relatively unex

169 ory of hearing loss, we estimate that 56% of hearing loss is genetic and 44% is not genetic.

170 Hearing loss is highly prevalent and may significantly a

171 ution to the global prevalence of hereditary hearing loss is still widely unknown.

172 Hidden hearing loss manifests as speech perception difficulties

173 Hearing rehabilitation for children with hearing loss may include use of hearing aids, cochlear i

174 Evaluation of hearing loss must be based on suspected diagnosis, type,

175 TEMENT People with age-related sensorineural hearing loss often struggle to follow speech in the pres

176 an listeners to examine potential effects of hearing loss on EEG correlates of speech envelope synchr

177 To better account for the full spectrum of hearing loss profiles, we used a Gaussian Mixture Model

178 Neural plasticity due to hearing loss results in tonotopic map changes.

179 We characterized the genetics of hearing loss throughout the Palestinian population, enro

180 People suffering from age-related hearing loss typically present with deficits in temporal

181 The outcome of AG-induced hearing loss was identified from audiometric and clinica

182 enty-one individuals with moderate to severe hearing loss were recruited.

183 Similarly, the tonotopic maps for the hearing loss without tinnitus group were significantly d

184 ants appear intermediate to the controls and hearing loss without tinnitus group.

185 he auditory midbrain of gerbils with "hidden hearing loss" through noise exposure that increased hear

186 cCMV and related sequelae (neurologic and/or hearing loss) following a maternal infection in the firs

187 ed diagnosis, type, laterality and degree of hearing loss, age of onset, and additional variables suc

188 redict which infants will have sensorineural hearing loss, among asymptomatic cCMV there are currentl

189 n-dependent diabetes mellitus, sensorineural hearing loss, and mild intellectual disability.

190 transducer current, and develop progressive hearing loss, becoming deaf by 8 months of age.

191 cteremic pneumonia, or bacteremia (including hearing loss, developmental delay, and speech delay, but

192 featuring varying degrees of high-frequency hearing loss, flat loss, mixed loss, and notched profile

193 While commonly associated with hearing loss, hyperacusis can also occur without hearing

194 ing loss, hyperacusis can also occur without hearing loss, implicating the central nervous system in

195 on the possible causal relationship between hearing loss, neural reorganisation, and cognitive impai

196 d map reorganization are a characteristic of hearing loss, not of tinnitus.

197 at majority (87%) of families with inherited hearing loss, panel-based genomic DNA sequencing, follow

198 n incomplete form of central compensation to hearing loss, rather than excessive adaptation.

199 xposures and late effects of cardiomyopathy, hearing loss, stroke, thyroid disorders, and diabetes we

200 ing a cutoff of 80% predicted probability of hearing loss, the positive predictive value of this mode

201 alestinian families with no prior history of hearing loss, we estimate that 56% of hearing loss is ge

202 This is particularly true for sensorineural hearing loss, which contributes to one third of all earl

203 e participants with bilateral high-frequency hearing loss, with and without tinnitus, and a control g

204 -limited settings often experience permanent hearing loss, yet there is no practical method to identi

205 hearing problems in noise, known as "hidden hearing loss," but existing studies are controversial.

206 ring difficulties in noise, known as "hidden hearing loss," but support for this hypothesis is contro

207 al studies have suggested a relation between hearing loss-induced tonotopic reorganization and tinnit

208 "Growing old" is the most common cause of hearing loss.

209 t of inner ear disorders such as age-related hearing loss.

210 m albumin, body mass index, and pre-existing hearing loss.

211 have been linked to auditory dysfunction and hearing loss.

212 tributor to the hearing handicap in cochlear hearing loss.

213 o assess the degree and underlying source of hearing loss.

214 mptomatic at birth, but 10%-15% will develop hearing loss.

215 /ba/ are evaluated across various degrees of hearing loss.

216 ontributes to the progression of age-related hearing loss.

217 ce scores were associated with lower risk of hearing loss.

218 provides a primer on diagnosing and managing hearing loss.

219 rders following noise exposure or conductive hearing loss.

220 for recessively inherited moderate to severe hearing loss.

221 exposure is the largest preventable cause of hearing loss.

222 of a "phantom" sound that often accompanies hearing loss.

223 lood flow reduction, which may contribute to hearing loss.

224 althy diet might reduce the risk of acquired hearing loss.

225 mon disease in young children, can result in hearing loss.

226 articipants (n = 238) developed any level of hearing loss.

227 ists in caring for the adult population with hearing loss.

228 nelle connectomics may result in progressive hearing loss.

229 ition even in individuals with no measurable hearing loss.

230 ncomplete penetrance as the reason for their hearing loss.

231 currently being investigated clinically for hearing loss.

232 dle ear may be able to reverse sensorineural hearing loss.

233 ud music too often, results in noise-induced hearing loss.

234 be a viable strategy to prevent age-related hearing loss.

235 ders and in 5 out of 28 (~18%) children with hearing loss.

236 nerate over time, giving rise to progressive hearing loss.

237 in IHCs are a potential cause of age-related hearing loss.

238 unknown about how efferent activity affects hearing mechanics.

239 eurons displayed auditory-evoked activity to hearing of female calls only if that neuron showed activ

240 lling and showed auditory-evoked activity to hearing of played-back female calls.

241 adults visited our clinic because of reduced hearing, only to learn that their hearing was clinically

242 st firing of mouse inner hair cells prior to hearing onset requires P2RY1 autoreceptors expressed by

243 are most effective when administered before hearing onset, after which therapeutic efficacy is signi

244 We show that, from birth to hearing onset, the auditory system relies on a consisten

245 At hearing onset, the MOC-OHC synapse presented facilitatio

246 activity-dependent calcium signaling around hearing onset.

247 than initiates, spontaneous activity before hearing onset.

248 action potentials disappeared rapidly after hearing onset.

249 nd coactivated frontostriatal networks after hearing onset.

250 stry payments by speakers of the Open Public Hearing (OPH) portion and the nature of their recommenda

251 irium; people with difficulty communicating, hearing or understanding; people from ethnic minority gr

252 Current approaches for diagnosis of hearing or vestibular disorders are mostly based on phys

253 airment (cognitive delay, cerebral palsy, or hearing or vision loss) at 22 to 26 months of age, corre

254 s in expression levels of these genes in the hearing organ could underlie the DFNA58 form of deafness

255 Here we demonstrate that, different from the hearing organ of vertebrate species, a nicotinic acetylc

256 The mammalian hearing organ, the cochlea, contains an active amplifier

257 tects sound wavelengths much larger than its hearing organ.

258 which become competent at about the onset of hearing (P12).

259 cta also occurred in inner hair cells of pre-hearing (P7) but not in adult mice.

260 ubulin mutation severely impairs the central hearing pathway most probably by progressive central whi

261 equal numbers of male and female mice with a hearing phenotype akin to human aging.

262 be an alternative to balance tumor control, hearing preservation and adverse effects.

263 The overall hearing preservation rate and toxicity of SRS was influe

264 AN loss is widely expected to cause hearing problems in noise, known as "hidden hearing loss

265 ions, including tactile and pain perception, hearing, proprioception, and control of blood pressure,

266 Hearing rehabilitation for children with hearing loss ma

267 Without hearing rehabilitation, hearing loss can cause detriment

268 -wide screens revealed positive selection on hearing-related genes in the ancestral branch of bats, w

269 High sensitivity and selectivity of hearing require an active cochlea.

270 Mammalian hearing requires the development of the organ of Corti,

271 An emerging doctrine in hearing research is that vertebrate primary auditory rec

272 pressed by active cochlear implants used for hearing restoration.

273 L and estimated the effectiveness of newborn hearing screening (HS) in identifying neonates with CMV-

274 Baseline and 3-year follow-up hearing sensitivities were assessed by pure-tone audiome

275 inner hair cell (IHC) ribbon synapses, lower hearing sensitivity and decreased ability to understand

276 st, mice on the CBA background retain better hearing sensitivity in old age.

277 l bundles, prevents hair cell loss, improves hearing sensitivity, and ameliorates vestibular dysfunct

278 nd genetic factors, leading to a decrease in hearing sensitivity, threshold and speech discrimination

279 abnormal hair bundle morphology and reduced hearing sensitivity.

280 MOC-OHC synapse is immature at the onset of hearing.SIGNIFICANCE STATEMENT The functional expression

281 han half of these patients lose this natural hearing soon after implantation.

282 theory in listeners with normal and impaired hearing, spanning a wide range of place-coding fidelity.

283 cells is differentially regulated during pre-hearing stages, with the former cells being more strongl

284 In normal-hearing subjects listening to CI simulated audio, we sho

285 enhance reproducibility in a NIRS study in a hearing task.

286 ound source microphone for fully implantable hearing technology such as CIs.

287 affect audiometric thresholds on a clinical hearing test.

288 have better average lung function and worse hearing than Black adults.

289 s, 149 citations), electronic reminders, and hearing their adherence score (37 participants, 90 citat

290 metric and clinical evaluation by a worsened hearing threshold compared with baseline during the 6-mo

291 terns and longitudinal change in audiometric hearing thresholds among 3,135 women (mean age = 59 year

292 loss" through noise exposure that increased hearing thresholds only temporarily.

293 e data suggest a means of maintaining normal hearing thresholds while protecting against noise-induce

294 s speech perception difficulties with normal hearing thresholds.

295 known not to cause any detectable change in hearing thresholds.

296 can mole-rats is adaptive, perhaps tailoring hearing to eusocial and subterranean lifestyles.

297 ion channels, which constitute the basis for hearing, touch, pain, cold, and heat sensation, among ot

298 h as feeling depressed, social, and calm and hearing voices.

299 of reduced hearing, only to learn that their hearing was clinically normal and should not cause commu

300 d to include those with considerable natural hearing which, when preserved, provides an improved hear