ライフサイエンスコーパス: helicity

1 ility using varied gate voltages and optical helicity.

2 istry that show a propensity to induce alpha-helicity.

3 serving transformations is equivalent to the helicity.

4 chiral sulfoxides in inducing backbone alpha-helicity.

5 hisms if and only if it is a function of the helicity.

6 ntly through the duplex depends upon the DNA helicity.

7 permeability, liquid crystallinity and chain helicity.

8 and henceforth recover the key properties of helicity.

9 ind monomeric sCT at acidic pH, inducing sCT helicity.

10 lix and that water is not necessary for PPII helicity.

11 intrinsic potential in this protein to gain helicity.

12 rearrangement with minor overall changes in helicity.

13 ins is essential for maintaining H. pylori's helicity.

14 rate classification and to correctly display helicity.

15 and circularly polarized light with opposite helicity.

16 opulation distribution and thereby the stack helicity.

17 electronic properties and, most importantly, helicity.

18 nd eventual refolding to apparently opposite helicity.

19 ified peptide (NYAD-1) showed enhanced alpha-helicity.

20 a conformational change with increased alpha-helicity.

21 minal deletions are accompanied by a loss of helicity.

22 l (Gly-Pro-Pro)5 "host" modules which ensure helicity.

23 ed kinetic acceleration with increasing ACTR helicity.

24 condense pDNA and significantly distort its helicity.

25 cence quantum yield for a system with higher helicity.

26 econd vortex, we found conservation of total helicity.

27 ith its sign determined by sign of the light helicity.

28 am patterns operating with opposite incident helicities.

29 o DBMs are the primary modulators of bZIP-bR helicities.

30 o have either increased or decreased overall helicities.

31 ical content compared with 37pA (5A, 12+/-1% helicity; 37pA, 28+/-2% helicity) and showed less self-a

32 Helicity, a topological measure of the intertwining of v

33 To understand how enhancing ACTR helicity accelerates binding, we derived a series of top

34 two stereodynamic units, which invert their helicities according to the length of the molecular gues

35 nd 2) predict how modulation of residual p53 helicity affects binding, in good agreement with experim

36 ernal twist to illustrate why the centreline helicity alone will lead to ambiguous results if a twist

37 While con-G exhibits no helicity alone, it undergoes a structural transition to

38 equences may reinforce the degree of peptoid helicity, although with a reduced content of chiral side

39 ynamics of fluids, redistributing energy and helicity among the length scales, triggering dissipative

40 lles around the receptor; (ii) loss of alpha-helicity and decreased interhelical packing interactions

41 4R, A168D, and A171P--show a decreased alpha-helicity and do not show a cooperative sigmoidal melt wi

42 This result has important implications for helicity and energy considerations in various physical c

43 We show that finger loop helicity and flexibility may underlie coupling to hundre

44 to a saddle-shaped particle involves loss of helicity and formation of loops in opposing antiparallel

45 carbon nanotube structures that have defined helicity and handedness and cover the entire chiral angl

46 r a staple) can covalently stabilize peptide helicity and improve its pharmacological properties.

47 these stapling peptides have increased alpha-helicity and improved proteolytic resistance without any

48 hile 40% trifluoroethanol (TFE) induces >90% helicity and is unperturbed by the spin label.

49 ered flexible C-terminus displaying residual helicity and large-amplitude backbone motions on the pic

50 ent protofilaments, enabling deviations from helicity and other sources of heterogeneity to be quanti

51 Protonation of the C-terminus promotes helicity and pore size.

52 no direct correlation between the fractional helicity and potency in signaling via the cAMP pathway.

53 of the BNIP3 transmembrane domain alters its helicity and protection of its backbone amides.

54 ntitative agreement with NMR-derived residue helicity and recapitulate the experimental observation t

55 inds to a nanotube of defined handedness and helicity and resembles a well-folded biomacromolecule wi

56 all of the peptides showed varying levels of helicity and structural stability in aqueous and membran

57 The helicity and structures of the chimeric peptides were co

58 ractively calculates and visualizes the mean helicity and the dissociation probability at each sequen

59 n of molecular chirality into supramolecular helicity and the molecules' inherent propensity for well

60 es, and their topological properties such as helicity and writhing have been studied theoretically an

61 le and applied to the peptide to enhance its helicity and, as a consequence, its potency and serum ha

62 th 37pA (5A, 12+/-1% helicity; 37pA, 28+/-2% helicity) and showed less self-association but, similar

63 hange in the myosin VI tail (31% increase in helicity) and when associated with lipid vesicles, it ca

64 that integrate molecular chirality, absolute helicity, and 3-D intrinsically chiral topological nets

65 ry of the solution structure, well-preserved helicity, and a significant number of native contacts.

66 o produce nanotubes with defined handedness, helicity, and endohedral filling.

67 he subunit dimensions, interaction energies, helicity, and geometrical constraints coming from the do

68 igned to emulate the amphipathic patterning, helicity, and hydrophobicity of SP-C, and to include no,

69 electric polarization with no change of spin-helicity, and present a phenomenological theory that suc

70 based on this conversion is shown to be spin-helicity- and magnetization-dependent.

71 We find that the alpha-helicity (approximately 70%), median melting temperature

72 l polaritons, where polaritons with opposite helicities are transported to opposite directions, is ve

73 Some basic properties of helicity are reviewed, with particular reference to (i)

74 Predicted curves display the mean helicity as a function of temperature or as derivative p

75 self-assembly into nanoribbons with specific helicity as a result of chirality-sensitive interactions

76 stereomeric complex will favor either P or M helicity as a result of minimizing steric interactions o

77 emaining residues do not exhibit significant helicity as determined by NMR.

78 escence complementation assays, and CD-based helicity assessments, we developed a NanoLuc binary tech

79 ine guest data; and comparisons of errors in helicity assignments from shifts and ellipticity data sh

80 The loss of helicity associated with increasing temperature may be v

81 enic in nature, with increased peptide alpha-helicity at a lower pH.

82 form of alpha-synuclein exhibits stabilized helicity at its N terminus and increased affinity for li

83 This interaction enables an enhanced valley helicity at room temperature (0.33 +/- 0.05) observed in

84 celles, there appears to be a break in alpha-helicity at sites 59-61, near the middle of the transmem

85 An increase in alpha-helicity at the N-terminus of aS is supported by CD data

86 shift indices reveal a region of significant helicity between residues 9 and 29.

87 ection process can be viewed as transferring helicity between scales, rather than dissipating it.

88 n solution, but that in longer oligomers the helicity breaks down and transmission of chirality in th

89 s maximize its "antimicrobialness") and its -helicity, but minimize mutational distance to known AMPs

90 the Kar3/Cik1 nonmotor region shows greater helicity by CD analysis and rotary-shadow EM reveals a s

91 It was possible to manipulate the degree of helicity by the alteration of only two amino acid residu

92 elicity state after the dissipation of twist helicity by viscosity.

93 d dissociation kinetics with increasing ACTR helicity can be directly attributed to smaller entropic

94 licity of the protein, and adoption of alpha-helicity can be induced by sodium dodecyl sulfate.

95 Here we show how spontaneous helicity can be induced in a synthetic polymeric nanobri

96 hat the chiral bias provided by the electron helicity can drive both reduction and oxidation in enant

97 Our results show that helicity can remain constant even in a viscous fluid and

98 linked peptides with substantially increased helicity, cell permeability, proteolytic stability, and

99 cules with a reduced degree of time-averaged helicity compared to those packed in undamaged fibrils-w

100 led analogs exhibited significantly enhanced helicity compared with the native peptide in a metal-fre

101 Thus, any deviation from helicity conservation is entirely due to the intrinsic t

102 Our results suggest that helicity conservation plays an important role in fluids

103 asi-classical limit of helicity emerges from helicity considerations for individual superfluid vortex

104 ution to achieve simultaneous handedness and helicity control for all three electronic types of carbo

105 d DNA to achieve simultaneous handedness and helicity control for all three types of nanotubes.

106 onstrating great opportunities for realizing helicity control of optoelectronic and thermal devices.

107 sport can also be significantly tuned by the helicity-control of surface state electrons.

108 Helicity-controllable focal line and focal point in the

109 Helicity-controllable real and virtual focal planes, as

110 bled asymmetric harmonic response to achieve helicity-controlled multiple structured wavefronts such

111 To ascertain whether this helicity could first be manifested inside the ribosomal

112 a methionine substitution indicated altered helicity coupled with reduced thermal stability.

113 intact but expanded by 40%, and total apoA-I helicity decreased from 95% to 72%.

114 Whereas the helicity dependent photocurrent with below-gap excitatio

115 larly polarized light, so-called all-optical helicity dependent switching, has renewed interest in th

116 nantiomers of heptahelical coumarins exhibit helicity-dependent chiroptical properties, namely, speci

117 mpower advanced research and applications in helicity-dependent focusing and imaging devices, angular

118 tion and polarization, which we attribute to helicity-dependent molecular ionization cross sections a

119 r-intuitive dual-polarity flat lens based on helicity-dependent phase discontinuities for circularly

120 Here we show a comprehensive study of the helicity-dependent photocurrent in (Bi1-x Sb x )2Te3 thi

121 photons are known to generate a directional helicity-dependent photocurrent in three-dimensional top

122 ac cone and the underlying mechanism for the helicity-dependent photocurrent is still not understood.

123 nic effect as the dominant mechanism for the helicity-dependent photocurrent.

124 We demonstrate that all-optical helicity-dependent switching (AO-HDS) can be observed no

125 magneto-optic waveguide media engenders spin-helicity-dependent unidirectional propagation.

126 Sequence analyses (helicity, disorder, and polarity) and solvent accessibil

127 The results show that increasing ACTR helicity does not alter the baseline mechanism of synerg

128 The possibility of a helicity-driven inverse cascade in 3D fluids had been re

129 Other mutants had only slight changes in helicity due to insertions in genes encoding MviN/MurJ,

130 monomer, leading to a perfect control of the helicity either by means of a remarkably low amount of s

131 us to explain how a quasi-classical limit of helicity emerges from helicity considerations for indivi

132 cores, protection factor-derived fractional helicities FH are assigned in the range 10-30 degrees C

133 s PF(i) that define uniquely high fractional helicities FH for the peptide Ala(n) regions.

134 three-dimensional topological insulator with helicity, fixing the orientation of their spin relative

135 bit strong circular polarization of the same helicity for a given twist angle, which suggests that th

136 acetylation results in a slightly increased helicity for the N-terminal ~10 residues of the protein,

137 tra of membrane-associated Fgp41 showed high helicity for the residues C-terminal of the FP.

138 dness in a process involving the transfer of helicity from 1a to 2c and the transfer of chirality fro

139 rough a reconnection enables the transfer of helicity from links and knots to helical coils.

140 residue 4 (L) to residue 9 (K) has a strong helicity from our simulations, which is supported by exp

141 efficient valley and spin control by optical helicity have recently been demonstrated in this materia

142 beta residues to promote alpha/beta-peptide helicity; here we show that an engineered ion pair array

143 ined by multifactors including charge, size, helicity, hydrophobicity, and so forth.

144 ontrolling motion of electrons using optical helicity, i.e., circularly polarized light.

145 NDI-PMDI pi-pi stacked dimers with opposite helicities in the solid state.

146 hat dimerization is facilitated by increased helicity in a thicker bilayer.

147 using NMR and CD confirm induction of alpha-helicity in Abeta mediated by ADH-41.

148 Robust optical helicity in all odd-layer-number crystals with inversion

149 e case (MAP-1) where stapling enhanced alpha-helicity in aqueous and lipid environments, leakage was

150 Kd of 80 nM, reflecting the large degree of helicity in C52L as measured by circular dichroism spect

151 fibers with helical tunnels of complementary helicity in CH2Cl2.

152 onal circularly polarized wave with the same helicity in forward and backward is generated based on n

153 ar dichroism and NMR indicated the degree of helicity in H2O, aqueous trifluoroethanol, or micelles.

154 The generation of a chiral helicity in helicenes was observed because of a severe i

155 pha-synuclein, the significant gain of alpha-helicity in K2 at low concentrations of sodium dodecyl s

156 ts were evaluated as possible sources of the helicity in linear perfluorinated alkanes through analys

157 not be directly correlated to the degree of helicity in micelles.

158 -is a surprisingly weak director of absolute helicity in nickel-salen foldamers.

159 fluorophenyl)ethyl)glycine monomers enforced helicity in peptoids that typically exhibit threaded loo

160 driving force for the origin of the observed helicity in perfluoroalkanes.

161 ved basis for understanding and manipulating helicity in real flows.

162 spite its relevance across a range of flows, helicity in real fluids remains poorly understood becaus

163 helix content in membranes rather than their helicity in solution.

164 The increased helicity in the cytosol is similar to that seen in previ

165 constraining role of the analogous magnetic helicity in the determination of stable knotted minimum-

166 valley selection rules, which have opposite helicity in the monolayer.

167 r dichroism (UV CD) spectra revealed greater helicity in the secondary structures of R56A and DeltaR5

168 domain 4 suggested that it may deviate from helicity in the vicinity of residue 155.

169 ide or nonylglucoside showed decreased alpha-helicity in transmembrane regions, decreased alpha-helic

170 We found that peptide helicity in water and interface increased linearly with

171 yclically constrained gamma residues promote helicity in water.

172 e-polymerized diacetylene vesicles, with 12% helicity induced in 50% v/v of trifluoroethanol.

173 s deep tuning is originated from the optical helicity-induced photocurrent which is shown to be enhan

174 chieved using a crafted combination of light helicity, intensity and wavelength, and is further tuned

175 Only ClCH2CH2Cl induces single-handed helicity into the nanotubes.

176 hing the feasibility of covalently triggered helicity inversion as a new mode of operation for chirop

177 nds, perturbation may involve either dynamic helicity inversion or a reversible change in the lanthan

178 A slight variation in the helicities is found to manifest in contrasting excited-s

179 Helicity is a molecular necessity in the higher series o

180 mpared to other methods, indicating that DNA helicity is best approximated by the quantum method.

181 rocess is cooperative and the supramolecular helicity is biased toward the helical preference of the

182 iginal twists of the interacting tubes, then helicity is conserved during reconnection.

183 resolved CD experiments show that almost all helicity is formed upon initial association of the prote

184 Although helicity is largely abolished in the unfolded states of

185 The induced preferred helicity is maintained by the OPV stacks even after the

186 sence of Na(+) and K(+) ions, no increase in helicity is observed with respect to the conformation in

187 Kinetic helicity is one of the invariants of the Euler equations

188 The exploitation of helicity is thus demonstrated to develop a novel set of

189 Helicity is, like energy, a quadratic invariant of the E

190 molecule, capable of freely adopting P or M helicity, is described for molecular recognition and chi

191 In the second step an inversion of the helicity (M-->P) of the cis azobenzene unit takes place.

192 p, wall shear stress, secondary flow degree, helicity, maximal velocity, and turbulent kinetic energy

193 ased peptide is in accord with the change in helicity measured by circular dichroism.

194 ons to quantitatively reproduce experimental helicity measurements obtained by circular dichroism.

195 The patterns in substrate helicity mirror those found in the unfolded state in the

196 Here we experimentally demonstrate a helicity multiplexed metasurface hologram with high effi

197 The demonstrated helicity multiplexed metasurface hologram with its high

198 emonstrate broadband, flexible, conformable, helicity multiplexed metasurface holograms operating in

199 electronic character, lengths, diameters and helicities, (n,m), as well as other amorphous, graphitic

200 ls of structural chirality: layer chirality, helicity of a basic repeating unit, mesoscopic helix and

201 results in topological fluid mechanics, the helicity of a flux tube can be calculated in terms of wr

202 r Pro(1171) or Glu(1168) increased the alpha-helicity of BAR and reduced its inhibitory activity in v

203 The measured alpha-helicity of each peptide was consistent with the expecte

204 In a wire-like device we trace the flow and helicity of exciton-polaritons expanding along its chann

205 ents of BBL, for example, find a decrease in helicity of helix 2 surrounding His166 on its protonatio

206 elity are interchangeable by controlling the helicity of incident light.

207 form of Syk is predicted to lead to reduced helicity of interdomain A and alter Syk's bias for cis b

208 The binding and helicity of KL(4) is dependent on the level of monounsat

209 opportunities for valley control through the helicity of light.

210 ation of the chirality of NDI-Delta into the helicity of nanotubes.

211 chiral bias to fully control the main chain helicity of polymers and assemblies.

212 dichroism analysis indicated that the alpha-helicity of psoriasin increases by more than 20% in the

213 The increases of bilayer thickness and helicity of rhodopsin are accompanied by higher metarhod

214 The effects of cross-linking on the alpha-helicity of selected peptides were examined by CD and NM

215 The role of the helicity of small molecules in enantioselective catalysi

216 index that is tunable through adjusting the helicity of structures, while the wavefront revolution p

217 Our results indicate that the nascent helicity of sub-domain LH plays a key role mediating the

218 Typically, switching the helicity of supramolecular assemblies involves external

219 o ligate and substantially enhance the alpha-helicity of the amphipathic C terminus of lacritin.

220 ic acid to the tweezer induces a predictable helicity of the bis(porphyrin), which is detected as a b

221 A processive change in the helicity of the body creates these waves and enables dir

222 n length but not cholesterol, suggesting the helicity of the bound state may be controlled by the bil

223 condary shifts at pH5.3 showed a decrease in helicity of the C-terminus of helix 2, where His166 is l

224 on are related to the handedness and the net helicity of the coassemblies, respectively.

225 s influence HAMP stability by modulating the helicity of the control cable segment.

226 forming a six-membered ring that favors one helicity of the electrocyclization transition state.

227 netic semiconductor and measured through the helicity of the electroluminescence due to the spin-vall

228 initialize their spin-valley state with the helicity of the excitation laser under small magnetic fi

229 are consistent with an increase in the alpha-helicity of the first six residues of aS, although a hig

230 he N-terminal tail or on how to modulate the helicity of the full-length peptides.

231 ble to control, for the first time, both the helicity of the helix and the form of the herringbone.

232 that are interchangeable by controlling the helicity of the incident light.

233 lens or a cylindrical lens, depending on the helicity of the incident light.

234 Specifically, by controlling the helicity of the input light, the positive and negative p

235 mages are interchangeable by controlling the helicity of the input light.

236 phospholipid vesicles, and adoption of alpha-helicity of the K-segment accounts for most of the confo

237 lical Dirac fermions, and that reversing the helicity of the light reverses the direction of the phot

238 Hall voltage whose sign is controlled by the helicity of the light.

239 in growth, we suggest that it originates the helicity of the nanotube.

240 he curvature of the cap and, presumably, the helicity of the nanotube.

241 f the free energy minimum and the structural helicity of the peptides are comparable in the implicit-

242 (-) of Ala25 is removed, consistent with the helicity of the peptides skewed toward the N-terminus.

243 role of the solvent, the metal ion, and the helicity of the polymer in the aggregation are discussed

244 The working model suggests that the observed helicity of the porphyrin tweezer is dictated via steric

245 nding is accompanied by an increase in alpha-helicity of the protein, and adoption of alpha-helicity

246 or and drive reversible changes in the alpha-helicity of the protein.

247 ctivity relationship revealed that the alpha-helicity of the S-peptide in the binding pocket correlat

248 Remarkably, the preferred helicity of the stacks of achiral AOPV3 can be retained

249 efficiency of which depends on the magnetic helicity of the structure.

250 In contrast, the helicity of the transmembrane domain of monomeric C991-5

251 eristics one has to understand the origin of helicity of their structures.

252 We measured the total helicity of thin-core vortex tubes in water.

253 e demonstrated a substantial increase in the helicity of this region in the presence of detergent mic

254 The nascent helicity of this sub-domain is conserved and we hypothes

255 33 leads only to marginal changes in average helicities on the ensemble level, underlying conformatio

256 investigated to understand the influence of helicity on excited-state and chiroptical properties.

257 or the polymer/metal ion ratio, and (b) the helicity on the surface and the interior of the particle

258 ological classification is determined by the helicity operator, which is generically non-Hermitian ev

259 orientation solely by changing either photon helicity or energy.

260 The conjecture that helicity (or knottedness) is a fundamental conserved qua

261 on of the inherent microscopic chirality and helicity present in individual phage particles at the ma

262 ither as 50% helicity temperatures or as the helicity probability at specific temperatures.

263 rminations of particle size/shape and apoA-I helicity provide additional support for the saddle-shape

264 (4,5)P2-bearing vesicles has increased alpha-helicity, providing direct spectroscopic proof of a conf

265 The flagellar helicity remained right-handed with a 1.3 mum pitch and

266 pling between this polarization and magnetic helicity required for multiferroicity.

267 in opposite directions upon excitation-spin-helicity reversals.

268 ng the applicability of the enone sector and helicity rules in dichroic studies and potential restric

269 s of the observed deviations from sector and helicity rules to determine the absolute configuration o

270 The helicity-selected topological surface state thus has a l

271 symmetry in bilayers, the photoluminescence helicity should no longer be locked to the valleys.

272 mbers) describing the winding of the complex helicity spectrum across the interface.

273 ing a new method for quantifying the spatial helicity spectrum, we find that the reconnection process

274 of Asp(632) also severely impaired the alpha-helicity, stability, and conformation of six-helix bundl

275 olution toward and maintenance of a constant helicity state after the dissipation of twist helicity b

276 function of sequence position either as 50% helicity temperatures or as the helicity probability at

277 of freedom in handedness and a multitude of helicities that give rise to three distinct types of ele

278 for vortex filaments appears to result in a helicity that does not retain its key attribute as a qua

279 Inducing alpha-helicity through side-chain cross-linking is a strategy

280 s suggest that small effects of mutations on helicity translate into a reduced ability to incorporate

281 which eventually undergo an inversion of the helicity triggered by water resulting from the water-med

282 cular dichroism revealed a loss of 31% alpha-helicity upon dimer dissociation.

283 c analogues and demonstrated increased alpha helicity upon peptide stapling.

284 This helicity varies from one bZIP-bR to another despite a si

285 s good predictions for the heat capacity and helicity versus temperature and urea.

286 is a rewarding challenge, where the released helicity/vorticity degree of freedom and higher skyrmion

287 alpha-Helicity was confirmed by a crystal structure of the MDM

288 Chemical reinforcement of BID BH3 alpha helicity was required to reveal the direct BID BH3-BAX a

289 By controlling the light helicity, we could confine the Bloch-Siegert shift to oc

290 chromenes 3 and 4 with varying magnitudes of helicity were designed in pursuit of o-quinonoid interme

291 Similar levels of alpha-helicity were observed in trifluoroethanol and the pepti

292 duced chiral inversion, whereas those with M-helicity were obtained from the gel form with chiral hol

293 on, gold nanoparticle superstructures with P-helicity were prepared from the sol form of the template

294 eters long 1D (bundled) fibers with opposite helicities, whereas BTA-Cel and BTA-OEG(4)-Man formed sm

295 erminus of pHLIP led to localized changes in helicity, whereas the coordination of sodium ions with t

296 They exhibit nascent helicity which has been localized to a segment referred

297 emblies occur without compromising intrinsic helicity, while both parallel and antiparallel beta-shee

298 However, there was also a prompt loss of helicity, whose amplitude increased with increasing Tf,

299 d best matched absorbance data and predicted helicity, with the exponential method displaying low-tem

300 In this setting, helicity would be expected to acquire its simplest form.