戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 ells arise from a common precursor cell, the hemangioblast.
2 from a common embryonic precursor termed the hemangioblast.
3 ls (BL-CFCs), the in vitro equivalent of the hemangioblast.
4 K1 and SCL are molecular determinants of the hemangioblast.
5  affecting hematopoiesis at the level of the hemangioblast.
6  of hematopoietic and endothelial cells, the hemangioblast.
7 ges may in fact function at the level of the hemangioblast.
8 pressing both Flk1 and SCL may represent the hemangioblast.
9 sized to arise from a common progenitor, the hemangioblast.
10 ar cells, the descendents of the presumptive hemangioblast.
11 al cells are derived from a common cell, the hemangioblast.
12 es arise from a common precursor, called the hemangioblast.
13 -sac blood island, which originates from the hemangioblast.
14 rs required for earlier specification of the hemangioblast.
15 ve erythroid development at the level of the hemangioblast.
16 cular events leading to the formation of the hemangioblast.
17  originate from a common precursor cell, the hemangioblast.
18  levels in cell populations enriched for the hemangioblast.
19 sidered to be the in vitro equivalent of the hemangioblast.
20 nic stem cells and impaired the formation of hemangioblasts.
21  early mesoderm and its differentiation into hemangioblasts.
22 ises primitive Hem and End cells, as well as hemangioblasts.
23 nd colonies are clonally generated by single hemangioblasts.
24 occur simultaneously from common precursors, hemangioblasts.
25 tical factors for the proliferation of human hemangioblasts.
26 we show that vessel phenotype resulting from hemangioblast activity can be altered by modulation of t
27  blood and blood vessels, provide functional hemangioblast activity during choroidal neovascularizati
28                                           WT hemangioblast activity in adult iNOS-/- recipients resul
29 scularization, thus revealing the functional hemangioblast activity of human hematopoietic cells.
30 ult hematopoietic stem cells have functional hemangioblast activity, that is, they can clonally diffe
31 ole early in development at the level of the hemangioblast, an embryonic progenitor of the hematopoie
32 olated cells expressing primitive erythroid, hemangioblast and endothelial makers were visible in the
33  leads to the opposite effect, inhibition of hemangioblast and hematopoietic development.
34  addition to mesoderm, these cells expressed hemangioblast and hematopoietic markers.
35 hematopoiesis, including the concepts of the hemangioblast and hemogenic endothelium.
36 GF-beta) superfamily, is required for proper hemangioblast and primitive hematopoietic development.
37 ing is critical for the proliferation of the hemangioblast and that cells expressing both Flk1 and SC
38 iption factor as a negative regulator of the hemangioblast and the endothelial lineage.
39 se ER71 and Etsrp caused strong expansion of hemangioblast and vascular endothelial lineages in a zeb
40 -/-) mouse result from a decreased number of hemangioblasts and a block in their ability to different
41 f ES cell differentiation to mesoderm and to hemangioblasts and acts within the LIF-gp130-Stat3 pathw
42  10% blasts from tertiary ELTC functioned as hemangioblasts and generated macroscopic Hem-End colonie
43 d may represent a common condition shared by hemangioblasts and HSCs.
44 f brachyury and flk-1 and differentiation to hemangioblasts and primitive and definitive hematopoieti
45  expressed gene signatures characteristic of hemangioblasts, and could be expanded, cryopreserved and
46  and functional characteristics of embryonic hemangioblasts, and that these can be used to directly i
47         We demonstrate that ACE+CD45-CD34+/- hemangioblasts are common yolk sac (YS)-like progenitors
48 ferentiate into ECs, suggesting that classic hemangioblasts are rare or nonexistent in Xenopus.
49  Padron-Barthe et al explore the role of the hemangioblast as the cell of origin for yolk sac blood a
50 h the embryologic, developmentally arrested, hemangioblast as the tumor cell of origin for VHL-associ
51 rp1 expression inhibits the specification of hemangioblasts, as shown by decreased expression of the
52 thetically, CD34(+)KDR(+) cells may comprise hemangioblasts bipotent for both lineages.
53 iogenesis, and has been postulated to induce hemangioblasts, bipotential precursors for blood and end
54    Significantly, proliferation of embryonic hemangioblasts (BL-CFCs) is regulated by hypoxia, as Arn
55 les between embryonic stem (ES) cell-derived hemangioblasts (Blast-Colony-Forming Cells, BL-CFCs) and
56                                              Hemangioblast, blood cell, cardiomyocyte, and vascular d
57  derive from a common progenitor, termed the hemangioblast, but the factor(s) specifying the developm
58 s arise from a common clonal progenitor, the hemangioblast, but this hypothesis has not been tested d
59 oderm, by measuring brachyury expression, to hemangioblasts, by measuring blast colony-forming cell (
60 dpc) represents an optimal window from which hemangioblasts can be isolated.
61 ells originate from embryologically-arrested hemangioblasts capable of blood and endothelial cell dif
62 ony-forming cell (BL-CFC), a progenitor with hemangioblast characteristics generated in embryonic ste
63 mesendoderm populations and were enriched in hemangioblast colony-forming cells (Bl-CFC).
64 ever, we discovered that LDN treatment after hemangioblast commitment enhanced primitive myeloid pote
65 on of Smad1 in embryoid body cultures before hemangioblast commitment limits hematopoietic potential
66 pleted in FlK1(+) mesoderm, at a stage after hemangioblast commitment, the pool of hematopoietic prog
67 1 and Gata2 are not observed at the onset of hemangioblast commitment.
68 topoietic stem cell is able to function as a hemangioblast, contributing both to blood reconstitution
69  from that found in the previously described hemangioblast-derived blast cell colonies in that they t
70 d by the transient expression of Numb in the hemangioblast-derived blast cell colonies.
71 sults indicate that ALK-1 signaling promotes hemangioblast development and hematopoiesis, as evidence
72                                              Hemangioblast development from ES cells was reduced 2- t
73 ule methoxyamine, affected cytokine-mediated hemangioblast development in vitro.
74 a (SCL), a transcription factor that directs hemangioblast development into blood cell precursors, re
75 ) ES cells, ALK-1 rescued both the defective hemangioblast development, and primitive erythropoiesis,
76 Our results show that in addition to delayed hemangioblast development, Hhex(-/-) ES-derived progeny
77 ) cells, to further define events leading to hemangioblast development.
78  acts upstream of scl and etsrp in zebrafish hemangioblast development.
79 c and endothelial development, downstream of hemangioblast development.
80 well as endothelial genes, in the definitive hemangioblasts (DHs).
81 lammation, is a novel marker for identifying hemangioblasts differentiating from human embryonic stem
82 ion of mesoderm: as a negative regulator for hemangioblast differentiation and hematopoiesis but alte
83       Therefore, Hex is a novel regulator of hemangioblast differentiation to hematopoietic and endot
84 ogenesis, including the pathways controlling hemangioblast differentiation.
85 er integrate the molecular events regulating hemangioblast differentiation.
86 wing that definitive HSCs do not function as hemangioblasts during normal development.
87 n-angiotensin system (RAS) directly regulate hemangioblast expansion and differentiation via signalin
88       ACE enzymatic activity is required for hemangioblast expansion, and differentiation toward eith
89 ficient to enhance commitment of mesoderm to hemangioblast fate.
90 to expand the number of cells that commit to hemangioblast fate.
91 iation of these mesodermal precursors to the hemangioblast fate; and VEGF is required for the product
92 ignaling molecule derived from PC, regulated hemangioblast formation and primitive hematopoiesis.
93 h, LPA functioned as a developmental cue for hemangioblast formation and primitive hematopoiesis.
94   Our results showed a profound reduction in hemangioblast frequency in the absence of endoglin.
95 rs of these bipotential progenitors-known as hemangioblasts-from human embryonic stem (hES) cells usi
96 he idea that a common progenitor, termed the hemangioblast, generates both hematopoietic and endothel
97 lved in insulin sensitivity, erythropoiesis, hemangioblast generation, and cellular redox control was
98 resulted in a temporal-sensitive increase in hemangioblast generation, precocious commitment to eryth
99 ut is dispensable for HE specification after hemangioblasts have been formed.
100    The roles of scl, ets and gata factors in hemangioblasts have been well defined, but the significa
101           These studies identified postnatal hemangioblasts in a CD34(+)KDR(+) cell subset, endowed w
102 ment and the specific signaling occurring in hemangioblasts in contrast to more advanced hematopoieti
103 vels of transcripts encoding markers for the hemangioblast, including Runx1, Scl, and Gata2.
104  its absence, primitive myeloid cells retain hemangioblast-like characteristics and fail to migrate.
105 argeted deletion of MAP2 specifically in the hemangioblast lineage resulted in abnormal vascular deve
106 composed of mesenchymal cells that expressed hemangioblast markers (CD31, CD34, C-kit, CXCR4, Runx1,
107 ands of primitive erythroid cells expressing hemangioblast markers (Flk1, Tal1/Scl1, platelet endothe
108 otent markers Oct4, SSEA-1, Rex1, and AP and hemangioblast markers CD133, Flk1, and c-kit.
109 sts, as shown by decreased expression of the hemangioblast markers, etsrp, fli1a, and scl; blocks pri
110            We developed a heuristic model of hemangioblast maturation, in part, to be explicit about
111 eries of experiments, which suggest that the hemangioblast may be a state of competence rather than a
112                   Although exceedingly rare, hemangioblasts may represent the lifetime source/reservo
113 experiments revealed that endoglin marks the hemangioblast on day 3 of EB differentiation.
114  cells develop from a common progenitor, the hemangioblast, or directly from mesodermal cells.
115 and conclude that embryonic progenitors with hemangioblast potential represent a possible cytologic e
116 lls in the embryo from a putative definitive hemangioblast precursor.
117 akaryocyte lineage initially originates from hemangioblast precursors during early gastrulation and i
118                  We found that a majority of hemangioblast precursors during early gastrulation conta
119  this region, HSCs are thought to arise from hemangioblast precursors located in the ventral wall of
120                   In Xenopus, the definitive hemangioblast precursors of the HSC lineage have been id
121 1+ cardiovascular progenitors, distinct from hemangioblast precursors, represents a mesodermal precur
122 eneration of Flk-1+ mesoderm, the Flk-1+Scl+ hemangioblast, primitive erythroid and endothelial cells
123 ine yolk sac, including overlapping waves of hemangioblast, primitive, erythroid, and definitive eryt
124 ors (NMPs) and the origins of a joint kidney-hemangioblast progenitor population.
125         Moreover, contribution by individual hemangioblast progenitors to both endothelial and hemato
126 ouble-negative gate unlocking entry into the hemangioblast program, in part by inhibiting TGFbeta sig
127 al gene regulatory network (GRN) controlling hemangioblast programming has been elucidated.
128 EBs during the appearance of precursors with hemangioblast properties, the blast colony-forming cells
129 ematopoiesis as well as a novel mechanism of hemangioblast regulation.
130                 Sibling cells generated by a hemangioblast, replated in unicellular culture, produce
131 h the genome-wide binding pattern of Ldb1 in hemangioblasts revealed a number of direct-target genes
132 es, to evaluate the self-renewal capacity of hemangioblasts, single CD34(+)KDR(+) cells were grown in
133 es derive from a common progenitor cell, the hemangioblast: specifically, the human cord blood (CB) C
134 indings point to a role for endoglin in both hemangioblast specification and hematopoietic commitment
135  demonstrated previously that Smad1 promotes hemangioblast specification, but then subsequently restr
136 ily responsible for initiation of definitive hemangioblast specification.
137 mon origin from mesodermal precursors called hemangioblasts, specified in the primitive streak during
138 e demonstrate a role for Runx1 (AML1) at the hemangioblast stage of hematopoietic and endothelial dev
139      Clonal analysis provided evidence for a hemangioblast that can give rise to two daughter cells:
140 orming cell represents the long-hypothesized hemangioblast, the common precursor of the hematopoietic
141 expression of Flk1 and Tal1, markers for the hemangioblast, the precursor of both blood and endotheli
142 omoting growth factor) and FLK1 (a marker of hemangioblasts, the bipotential progenitor of endothelia
143  apex of the hierarchy programming the adult hemangioblast, thus illustrating that miRNAs can act as
144 opoietic or endothelial fate of hESC-derived hemangioblasts, thus providing novel opportunities for h
145 t Hex is required for differentiation of the hemangioblast to definitive embryonic hematopoietic prog
146 des that regulate the differentiation of the hemangioblast to hematopoietic and endothelial cells are
147  the Notch pathway can efficiently respecify hemangioblasts to a cardiac fate, resulting in the gener
148         Differentiation to both mesoderm and hemangioblasts was lower in Shp-2Delta46-110 cells compa
149 ive documentation of proepicardially derived hemangioblasts, which can differentiate into erythrocyte
150                             The existence of hemangioblasts, which serve as common progenitors for he
151  arise from a pool of pluripotential cells ("hemangioblasts") within the Drosophila embryonic mesoder

 
Page Top