ライフサイエンスコーパス: hematogenous

1 agalactiae (34%), and 52% of all cases were hematogenous.

2 tes of dissemination including lymphatic and hematogenous.

3 locate to the gastrointestinal tract through hematogenous and enteral routes.

4 n blood and lymphatic vessels indicated both hematogenous and lymphatic dissemination.

5 cells from the primary tumor spread through hematogenous and lymphatic routes, and the primary tumor

6 ate systemically via infected macrophages by hematogenous and lymphatic routes.

7 primary sites, to their transit through the hematogenous and/or lymphatic systems, and ending with t

8 eritoneal, direct invasion, transperitoneal, hematogenous, and extramural venous invasion.

9 Subacute, hematogenous, and extrapulmonary disease tends to be mor

10 the mechanical transmission of the virus via hematogenous arthropods.

11 ecting survival in a murine genetic model of hematogenous C. albicans infection.

12 To test whether hematogenous C. muridarum can spread to and establish a

13 esistant adhesive interactions essential for hematogenous cancer dissemination.

14 ivation by binding to CLEC-2 and facilitates hematogenous cancer metastasis and cancer-associated thr

15 ng very rare cell types such as the study of hematogenous cancer metastasis.

16 lay an important role during early stages of hematogenous cancer metastasis.

17 hought to mediate sialyl Lewis A/X-dependent hematogenous cancer metastasis.

18 (AmB) were investigated in a rabbit model of hematogenous Candida albicans meningoencephalitis.

19 Hematogenous Candida meningoencephalitis (HCME) is a rel

20 tly tested for virulence in a mouse model of hematogenous candidiasis.

21 shock with multiple organ injury early after hematogenous candidiasis.

22 -mer peptide, designated I-peptide, inhibits hematogenous carbohydrate-dependent cancer cell coloniza

23 Hematogenous CCA metastases commonly occur at distant or

24 Newly infiltrating, hematogenous CD16(+) monocytes were detected in a periva

25 ated as mediators of apoptosis, primarily in hematogenous cell systems, but their role in neuronal ap

26 those of mice lacking CD36 both in brain and hematogenous cells (CD36(-/-) -->CD36(-/-); - 72%).

27 ansgenic mice as donors, the distribution of hematogenous cells after bone marrow transplantation was

28 s suggest that a significant number of donor hematogenous cells are able to infiltrate into the brain

29 microglia and endothelial cells), and not in hematogenous cells is involved in the damage.

30 evade complement-mediated clearance from the hematogenous circulation is a novel virulence attribute

31 introduced to resemble ascending vaginal and hematogenous colonization.

32 cated infection (n=104), and bacteremia with hematogenous complications (n=157).

33 in clonal complex (CC) 30 is associated with hematogenous complications and (2) test the hypothesis t

34 l virulence factors may increase the risk of hematogenous complications during methicillin-resistant

35 ions (V-MICs) and MRSA clone type on risk of hematogenous complications from MRSA BSI during implemen

36 ignificant trend toward increasing levels of hematogenous complications.

37 ted a significant trend toward more frequent hematogenous complications.

38 RB6-8C5 were more resistant to experimental hematogenous disseminated candidiasis if they received M

39 antibody (MAb) B6.1 increases resistance to hematogenous disseminated candidiasis in normal and SCID

40 ative urine cultures in patients at risk for hematogenous disseminated candidiasis is controversial.

41 isms of bone infection followed a pattern of hematogenous dissemination (67%), direct inoculation (25

42 transgenic expression of LMO1 also promoted hematogenous dissemination and distant metastasis, which

43 Inoculation resulted in hematogenous dissemination and logarithmic growth within

44 It develops after hematogenous dissemination and subsequent invasion of th

45 Engagement of JAM-A is required for reovirus hematogenous dissemination but is dispensable for neural

46 M33 does not have a role in cell-associated hematogenous dissemination but is required for viral amp

47 protein sigma1s is a critical determinant of hematogenous dissemination by type 1 reoviruses, which r

48 more, association of specific genotypes with hematogenous dissemination early in the disease course h

49 Less commonly, skin lesions may arise from hematogenous dissemination in compromised hosts with inv

50 There was a small but significant effect on hematogenous dissemination in favor of the CRT group (35

51 types that pose the greatest risk of causing hematogenous dissemination in humans.

52 ificant association between the frequency of hematogenous dissemination in Lyme disease patients and

53 euritis (Bannwarth syndrome), argues against hematogenous dissemination in Lyme neuroborreliosis.

54 hat apoptosis, which occurs at 24-48 h after hematogenous dissemination in the lungs is an important

55 es, and endothelial cells may regulate their hematogenous dissemination in the microvasculature.

56 Hematogenous dissemination is important for infection by

57 .045), providing clinical corroboration that hematogenous dissemination is related to the genetic sub

58 Hematogenous dissemination is thought to be a late event

59 limits the intravegetation proliferation and hematogenous dissemination of a tPMPs strain in experime

60 the investigation of factors involved in the hematogenous dissemination of B. burgdorferi.

61 Hematogenous dissemination of bacteria was observed micr

62 oor outcome of cancer patients occurs during hematogenous dissemination of cancer cells.

63 r cell aggregates that may contribute to the hematogenous dissemination of cancer.

64 Adhesion interactions during hematogenous dissemination of Candida albicans likely in

65 Since hematogenous dissemination of circulating tumor cells is

66 al protein 1 (tPMP-1) on the progression and hematogenous dissemination of experimental endocarditis

67 Hematogenous dissemination of HCMV to different organ si

68 Hematogenous dissemination of HCMV via infected monocyte

69 cytes are proposed to play a key role in the hematogenous dissemination of human cytomegalovirus (HCM

70 eral blood monocytes are responsible for the hematogenous dissemination of human cytomegalovirus (HCM

71 Monocytes play a key role in the hematogenous dissemination of human cytomegalovirus (HCM

72 meningoencephalitis develops as a result of hematogenous dissemination of inhaled Cryptococcus neofo

73 Hematogenous dissemination of melanoma is a life-threate

74 ng the central nervous system, and inhibited hematogenous dissemination of primary lymphoma cells.

75 into potential adhesive mechanisms promoting hematogenous dissemination of prostate tumor cells into

76 ction and are proposed to be responsible for hematogenous dissemination of the virus.

77 tion and are a key cell type responsible for hematogenous dissemination of the virus.

78 ction and are proposed to be responsible for hematogenous dissemination of the virus.

79 >90% of cancer-related deaths, is enabled by hematogenous dissemination of tumor cells via the circul

80 Metastases largely rely on hematogenous dissemination of tumor cells via the vascul

81 and fibrin(ogen) play critical roles in the hematogenous dissemination of tumor cells, including col

82 Endothelial adhesion is necessary for the hematogenous dissemination of tumor cells.

83 ment of metastasis function, the hallmark of hematogenous dissemination of tumor cells.

84 These data support the view of hematogenous dissemination of ZIKV and implicate AXL as

85 halmitis is a serious infection secondary to hematogenous dissemination or direct inoculation of the

86 By comparison, protection against hematogenous dissemination required the induction of IL-

87 pled from agr activation kinetics, increased hematogenous dissemination to certain tissues during sep

88 verity, and MRSA density in skin, as well as hematogenous dissemination to kidney.

89 Inhibition of IL-17A but not IL-22 led to hematogenous dissemination to kidneys, which correlated

90 Proposed mechanisms of spread include hematogenous dissemination via venous sinuses, cerebrosp

91 Bacteremia with hematogenous dissemination was first detected 2 days aft

92 Instead, sigma1s mediates hematogenous dissemination within the infected host, whi

93 i sensu stricto may affect the occurrence of hematogenous dissemination, 104 untreated adults with er

94 also lead to gastrointestinal involvement by hematogenous dissemination, resulting in complications a

95 llular changes that allow for HCMV entry and hematogenous dissemination.

96 e aberrant biological activity that promotes hematogenous dissemination.

97 st factors, may be important determinants of hematogenous dissemination.

98 ansiently adherent leukocytes and subsequent hematogenous dissemination.

99 Tumors require a blood supply for growth and hematogenous dissemination.

100 ough the gastrointestinal tract, followed by hematogenous dissemination.

101 ion using a rabbit model of endocarditis and hematogenous dissemination.

102 amined with an in vivo model of experimental hematogenous E. coli K1 meningitis and an in vitro model

103 l nervous system in the newborn rat model of hematogenous E. coli meningitis than the parent strain.

104 inal fluid of newborn rats with experimental hematogenous E. coli meningitis, suggesting that the Glc

105 one-related plasmacytomas than in those with hematogenous EMM.

106 t role in the replication of B. anthracis in hematogenous environments.

107 Hematogenous hepatic metastases developed in 38 of 244 p

108 ce of LPS receptor (TLR4) is not required on hematogenous immune cells but is required on cells that

109 c gradient that guides the transmigration of hematogenous immune cells into the injured nerve.

110 Hematogenous immune cells may migrate to/infiltrate the

111 cedure resulted in a marked propensity for a hematogenous implant-related infection comprised of sept

112 inhibited biofilm formation in vitro and the hematogenous implant-related infection in vivo.

113 Hematogenous implant-related infections following bacter

114 be therapeutically targeted against Saureus hematogenous implant-related infections.

115 more resistant than control mice to a lethal hematogenous infection by C. albicans, as evidenced by e

116 Herein, we developed a model of hematogenous infection in which an orthopedic titanium i

117 iver and lung dysfunction were studied after hematogenous infection of Sprague-Dawley rats with 10(9)

118 e prototypic wild-type CDV(R252) showed that hematogenous infection of the choroid plexus is not a si

119 ts (n = 43) were perfused over 180 min after hematogenous infection with 10(9) live Escherichia coli

120 Coinciding with hematogenous infection, most patients had >/=2 infected

121 res of Candida albicans in a rabbit model of hematogenous infection.

122 ment and invade the tissue parenchyma during hematogenous infection.

123 les in host defense against cutaneous versus hematogenous infection.

124 Among patients with hematogenous infections, odds of endogenous endophthalmi

125 Among inpatients with hematogenous infections, the overall incidence rate of p

126 developing endophthalmitis in patients with hematogenous infections.

127 njury and is associated with infiltration of hematogenous innate immune cells into the injured cord.

128 ine system may be of particular interest for hematogenous leukocyte infiltration of the central nervo

129 In axotomized DRGs, few hematogenous leukocytes are detected and resident macrop

130 Hematogenous leukocytes infiltrate the CNS after inflamm

131 ) from perihepatic peritoneal metastasis and hematogenous liver metastases.

132 routes of metastasis, including peritoneal, hematogenous, lymphatic, and nerve-related.

133 is virus-induced demyelination, depletion of hematogenous macrophages abrogates the demyelinating pro

134 The lysozyme M EGFP-knockin mouse tags hematogenous macrophages, but not microglia.

135 After stroke, microglia and hematogenous macrophages, together referred to as MPhi,

136 cularity and perhaps cancer dissemination by hematogenous means.

137 the blood-brain barrier in the experimental hematogenous meningitis animal model.

138 cal isolate HI689 in the infant rat model of hematogenous meningitis, an established model of invasiv

139 In a murine model of hematogenous meningitis, mice infected with beta-h/c mut

140 e the blood-brain barrier using our model of hematogenous meningitis.

141 BB in the neonatal rat model of experimental hematogenous meningitis.

142 both in vitro and in a newborn rat model of hematogenous meningitis.

143 ent strain in newborn rats with experimental hematogenous meningitis.

144 smolarity) in newborn rats with experimental hematogenous meningitis.

145 Conclusion Differentiating hematogenous metastases and LPI is important for radiolo

146 tases and LPI is important for radiologists; hematogenous metastases are associated with shorter surv

147 Hematogenous metastases are rarely present at diagnosis

148 are not highly vascularised tumours, making hematogenous metastases uncommon.

149 Hematogenous metastases were associated with significant

150 iations and prognostic importance of LPI and hematogenous metastases were studied by using univariate

151 ls (CTCs) represent a surrogate biomarker of hematogenous metastases.

152 ted in reduced tumor vasculature and limited hematogenous metastases.

153 16; 95% CI: 1.94, 4.56) were associated with hematogenous metastases.

154 Hematogenous metastasis (blood tumor burden, lung metast

155 c evidence that platelets play a key role in hematogenous metastasis and contribute to this process b

156 Our results highlight hematogenous metastasis as an important mode of ovarian

157 in samples from the 4 patients who developed hematogenous metastasis but in none of tumors from patie

158 have been able to observe the steps in early hematogenous metastasis by epifluorescence microscopy of

159 Thus, MMP-9 expression is required for hematogenous metastasis in a murine prostate model syste

160 ome 3 that reduced relative tumor growth and hematogenous metastasis in the SS.BN3(IL2Rgamma) consomi

161 red as a predictor and therapeutic target of hematogenous metastasis in TNBC patients.

162 A hematogenous metastasis mouse model revealed that PPM1A

163 fficking in both acute and chronic settings, hematogenous metastasis of carcinoma cells, effector mec

164 abiosis model that demonstrates preferential hematogenous metastasis of ovarian cancer to the omentum

165 r cells to the vascular endothelium and that hematogenous metastasis originates from the proliferatio

166 Using a mouse model of hematogenous metastasis to the lung, we observed decreas

167 A higher AR expression increases ccRCC hematogenous metastasis yet decreases ccRCC lymphatic me

168 orthotopic tumors, or intravenously to model hematogenous metastasis, and prospectively enrolled rand

169 orthotopic tumors, or intravenously to model hematogenous metastasis, and prospectively enrolled rand

170 umor cells in distant organs is required for hematogenous metastasis, but the tumor cell surface mole

171 ere in a model for TF-dependent experimental hematogenous metastasis, that TF supports metastasis by

172 use the lungs are the most common target for hematogenous metastasis, this research offers a plausibl

173 f the main host responses to coagulation for hematogenous metastasis, we examined lung metastases aft

174 f how platelets contribute to the process of hematogenous metastasis.

175 evealed that TM is a powerful determinant of hematogenous metastasis.

176 within the microvasculature and facilitates hematogenous metastasis.

177 through it occurs at least as frequently as hematogenous metastasis.

178 servation of how macrophages are involved in hematogenous metastasis.

179 cular endothelium, two critical processes in hematogenous metastasis.

180 The liver is a common site of hematogenous metastasis.

181 ed fibrinolysis had no significant impact on hematogenous metastasis.

182 s may contribute to the role of platelets in hematogenous metastasis.

183 ons, except for the one SM that succumbed to hematogenous metastasis.

184 nd histopathological parameters with risk of hematogenous metastasis.

185 ood vessels, thereby promoting lymphatic and hematogenous metastasis.

186 uman soft tissue sarcomas have a distinctive hematogenous metastatic pattern (predominantly lung), an

187 es (IMPs), which ablate a specific subset of hematogenous monocytes (hMos).

188 y demyelinating stages comprised CCR1+/CCR5+ hematogenous monocytes and CCR1-/CCR5- resident microgli

189 ) axis is a dominant pathway responsible for hematogenous omental metastasis.

190 s and reactive oxygen species in eliminating hematogenous or intracellular MRSA, these findings may o

191 e nervous system can be affected directly by hematogenous or local spread of lymphoma.

192 vo tumors that develop in transplanted donor hematogenous or lymphoid cells after transplantation.

193 The spread of reactivated HCMV via the hematogenous or neural route usually results in severe d

194 inal tract and disseminates systemically via hematogenous or neural routes.

195 ests that resident PNS-MPs along with MPs of hematogenous origin may be involved, but whether these t

196 cus aureus is the most common cause of acute hematogenous osteoarticular infections (AHOAIs) in child

197 graphy in pediatric cases of suspected acute hematogenous osteomyelitis (AHO) with nondiagnostic radi

198 In children, hematogenous osteomyelitis is an infection that primaril

199 n summary, our mouse model of staphylococcal hematogenous osteomyelitis precisely reproduces most fea

200 ry cavity consistent with a subacute form of hematogenous osteomyelitis termed a Brodie abscess.

201 thritis/pyomyositis, nontraumatic meningitis/hematogenous osteomyelitis, and pneumonia) each had a si

202 and in distinguishing it from unifocal acute hematogenous osteomyelitis.

203 ue to limited virus delivery to the brain by hematogenous pathways.

204 91 patients with a hematogenous PJI and 108 concomitant prosthetic joints w

205 We included 91 patients with a hematogenous PJI and 108 concomitant prosthetic joints.

206 During an episode of hematogenous PJI, concomitant asymptomatic prosthetic jo

207 ent bacteremia may be a potential source for hematogenous PJI.

208 yzed a cohort of patients with a late acute (hematogenous) PJI between 2005-2015 who had concomitant

209 al models: efficacy in Staphylococcus aureus hematogenous pneumonia and inhalation anthrax but no act

210 study to investigate the importation of the hematogenous precursors of thymic DCs.

211 at labels CD14 antigen present on monocytes, hematogenous precursors of tissue macrophages, did not l

212 Hematogenous precursors repopulate the thymus of normal

213 was radiosensitive and rapidly replaced from hematogenous precursors, whereas the other was relativel

214 each of these key hemostatic factors on the hematogenous pulmonary metastasis of 2 established murin

215 hat was attenuated for virulence in a murine hematogenous pyelonephritis infection model.

216 y (IM) metastasis is generally attributed to hematogenous rather than lymphatic spread.

217 jor route of drug delivery in this system is hematogenous rather than transscleral.

218 f CCR2(+) MOs/MPs rather than blocking their hematogenous recruitment.

219 r invasion of placental trophoblasts and the hematogenous release of placental debris.

220 rains induced equivalent rates and extent of hematogenous renal infection, only the tPMP(r) strain di

221 al metastases but almost never spreads via a hematogenous route and rarely spreads to lymphatics.

222 Our data also underscore that the hematogenous route might play a pivotal role in viral di

223 t manner, suggesting that fusobacteria use a hematogenous route to reach colon adenocarcinomas.

224 ination from and/or toward the brain via the hematogenous route was provided, confirming a hypothesis

225 We report that IPCs can enter PLNs via a hematogenous route, which involves a multistep adhesive

226 disseminated lymphatically rather than by a hematogenous route.

227 cells to metastasize via either lymphatic or hematogenous routes.

228 e 1 Lang (T1L), which disseminates solely by hematogenous routes.

229 Current evidence supports hematogenous seeding of bacteria from a dental focus as

230 E), a severe intraocular infection caused by hematogenous seeding of mycotic organisms to the eye.

231 rally injected alphaviruses enter the CNS by hematogenous seeding of the CVOs followed by centripetal

232 ater time points after infection, cells from hematogenous sources helped to partially replenish the p

233 ltapvl, and LACDeltahla D14 survivors had no hematogenous spread (P < .001).

234 d 72% of LACDeltahla-infected rabbits had no hematogenous spread and similar lung and bone bacterial

235 Our data demonstrate direct hematogenous spread as a dissemination route that contri

236 specificity of the o1s protein for promoting hematogenous spread as a platform to uncover a role for

237 Two prominent possibilities include hematogenous spread by leukocytes and neural spread by a

238 Hematogenous spread can occur to many sites, but spleen,

239 in or bone) disease, probably resulting from hematogenous spread from a primary lung infection, was m

240 and 85A to reduce lung pathology and prevent hematogenous spread in guinea pigs challenged with a low

241 and vascular endothelium may regulate their hematogenous spread in the microvasculature.

242 required for S. aureus fitness in vivo in a hematogenous spread infection model and a nasal colonisa

243 portion of distant recurrences suggests that hematogenous spread is a more common metastatic pathway

244 terized by dysregulated immune responses and hematogenous spread of Bacillus anthracis, leading to ex

245 luble plasma FN and, thus, can happen during hematogenous spread of cancer cells at high plasma FN co

246 Modeling the hematogenous spread of cancer cells to distant organs po

247 expressed on tumor cells contributes to the hematogenous spread of colon carcinoma.

248 did not protect challenged guinea pigs from hematogenous spread of organisms to the spleen.

249 The molecular mechanisms underlying the hematogenous spread of PCs outside the bone marrow are o

250 C57BL/6 mice early during infection reduced hematogenous spread of the bacilli, suggesting that MMPs

251 irus (HCMV) pathogenesis is dependent on the hematogenous spread of the virus to host tissue.

252 The presence of SV40 in PBMCs suggests that hematogenous spread of viral infection may occur.

253 ection of vascular endothelial cells and the hematogenous spread of virus-infected leukocytes from me

254 Protecting the fetus from the hematogenous spread of viruses requires multifaceted lay

255 However, mechanisms that underlie reovirus hematogenous spread remain undefined.

256 A propensity for hematogenous spread with resulting contamination of auto

257 ection through transscleral diffusion, local hematogenous spread, and possibly movement through the u

258 yoepithelial differentiation, proclivity for hematogenous spread, and slow but progressive clinical c

259 ichia coli meningitis develop as a result of hematogenous spread, but it is not clear how circulating

260 Outcomes (mortality, hematogenous spread, lung and bone involvements) of rabb

261 llary beds (such as within the brain) during hematogenous spread, thereby facilitating blood-to-brain

262 To decipher the mechanism of hematogenous spread, we focused on the viral dysregulati

263 ized by a propensity for early lymphatic and hematogenous spread.

264 aperitoneal inoculation were consistent with hematogenous spread.

265 illimeters and cells lack routes for distant hematogenous spread.

266 rst immune competent mouse model for distant hematogenous spread.

267 o be required for early lung involvement via hematogenous spread.

268 hatics are an important conduit for reovirus hematogenous spread.IMPORTANCE Type 1 interferons (IFN-1

269 olves lymphatic dissemination in addition to hematogenous spreading.

270 at IRS4 is not significantly involved in the hematogenous stage of disease.

271 ut how ILC2s egress from the bone marrow for hematogenous trafficking.

272 ysical and immunological barrier against the hematogenous transmission of viruses from mother to fetu

273 can originate from the oral cavity following hematogenous transmission.

274 ing from the lower reproductive tract or via hematogenous transmission.

275 nocrotaline pyrrole in the liver followed by hematogenous transport to the lung where it injures pulm

276 Hematogenous tumor cell dissemination is a key event in

277 mic domain to support the complex process of hematogenous tumor cell dissemination.

278 uring conventional hepatectomy might enhance hematogenous tumor cell spread.

279 Tissue factor also supports hematogenous tumor dissemination.

280 ghlights how this interaction is involved in hematogenous tumor metastasis.

281 ns of thrombospondin-1, which is involved in hematogenous tumor spread, invasion and angiogenesis, an

282 inical trials for the treatment of solid and hematogenous tumors.

283 The role of hematogenous vasculature and development of angiogenic b

284 ti-step carcinogenesis and in the control of hematogenous versus lymphatic metastasis are unknown.

285 Hematogenous vertebral osteomyelitis (HVOM) is an incomp

286 promote subsequent infection of T cells and hematogenous virus spread.

287 Fifty-two were hematogenous, with poorer prognoses, and 88% were caused