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1 NA and histone hypermethylation and impaired hematopoietic differentiation.
2 e regulation during vascular development and hematopoietic differentiation.
3 oietic stem cells (HSCs) to permit efficient hematopoietic differentiation.
4 e-regulated miRs-126/126* and analyzed their hematopoietic differentiation.
5 ay participate in stem cell self-renewal and hematopoietic differentiation.
6 many cell types, including putative roles in hematopoietic differentiation.
7 f healthy donors, and could be redirected to hematopoietic differentiation.
8 mooth muscle cell investment of vessels, and hematopoietic differentiation.
9 es, including RUNX1, a critical regulator of hematopoietic differentiation.
10 2 family members have been identified during hematopoietic differentiation.
11 ht to derive from a common progenitor during hematopoietic differentiation.
12 rough interaction with Gfi proteins controls hematopoietic differentiation.
13 ally-structured transcriptional landscape of hematopoietic differentiation.
14 context-sensitive roles at defined stages of hematopoietic differentiation.
15 uggest that forced ABCG2 expression prevents hematopoietic differentiation.
16 id not, however, extend to the next level of hematopoietic differentiation.
17 independent of c-Mpl to promote multilineage hematopoietic differentiation.
18 cNAcylation is involved in the regulation of hematopoietic differentiation.
19 , p300, but not CBP, is essential for proper hematopoietic differentiation.
20 on of genomic instability, and inhibition of hematopoietic differentiation.
21 receptors do not play an instructive role in hematopoietic differentiation.
22 Evi27 expression is tightly regulated during hematopoietic differentiation.
23 of CBP, but not p300, is required for normal hematopoietic differentiation.
24 adult mice contain a remarkable capacity for hematopoietic differentiation.
25 ncing data and detect important landmarks of hematopoietic differentiation.
26 s relatively inefficient at the induction of hematopoietic differentiation.
27 important role in supporting and regulating hematopoietic differentiation.
28 point to an essential role for Ptp gamma in hematopoietic differentiation.
29 l system for the study of various aspects of hematopoietic differentiation.
30 of a ventral source of signal(s) controlling hematopoietic differentiation.
31 ne expression pattern for specific stages of hematopoietic differentiation.
32 of growth factors plays an important role in hematopoietic differentiation.
33 tination of CDK2, associated with a block in hematopoietic differentiation.
34 d assessed the impacts on HbF production and hematopoietic differentiation.
35 ll type-specific chromatin landscape driving hematopoietic differentiation.
36 myeloid leukemia (AML), as well as in normal hematopoietic differentiation.
37 event silencing of ANKRD26 expression during hematopoietic differentiation.
38 riptional regulatory network governing human hematopoietic differentiation.
39 itulates the patient disease phenotypes upon hematopoietic differentiation.
40 d in severe telomere shortening and impaired hematopoietic differentiation.
41 gene expression across the genome throughout hematopoietic differentiation.
42 w cytometry to assess inhibition of mIDH2 on hematopoietic differentiation.
43 cellular heterogeneity reflective of normal hematopoietic differentiation.
44 ing to dyserythropoiesis and an imbalance of hematopoietic differentiation.
45 hypermethylation phenotype that dysregulates hematopoietic differentiation.
46 ancy and dynamics across different stages of hematopoietic differentiation.
47 EST recruitment and MYC repression to govern hematopoietic differentiation.
48 ethylation dynamics and normal and malignant hematopoietic differentiation.
49 se-associated phenotypes, including impaired hematopoietic differentiation.
50 d decay, which, in turn, results in impaired hematopoietic differentiation.
51 tic impact of this robust demethylase during hematopoietic differentiation.
52 ator of hematopoiesis, at multiple stages of hematopoietic differentiation.
53 CHD7 acts to suppress hematopoietic differentiation.
54 relatively few transcription factors control hematopoietic differentiation.
55 ls, and that its expression increases during hematopoietic differentiation.
56 expressing Etv2 (ER71) and Tal1 that undergo hematopoietic differentiation.
57 odulating GATA-2 at the protein level during hematopoietic differentiation.
58 , is an indispensible epigenetic governor of hematopoietic differentiation.
59 cell (HSPC) gene expression programs during hematopoietic differentiation.
60 were collectively co-regulated during normal hematopoietic differentiation.
61 d epigenetic regulation that is required for hematopoietic differentiation.
62 intain a normal karyotype and are capable of hematopoietic differentiation.
63 gnals that induce early mesoderm to initiate hematopoietic differentiation.
64 ent reveals that methylation is critical for hematopoietic differentiation.
65 vel marker of this and other stages of early hematopoietic differentiation.
66 ating factor (GM-CSF), which are involved in hematopoietic differentiation and activation of immune c
67 athways, including developmental patterning, hematopoietic differentiation and antiviral defense.
69 his article, we describe the role of TEL2 in hematopoietic differentiation and cellular transformatio
70 he onset of EKLF and GATA1 expression during hematopoietic differentiation and demonstrate that EB di
72 e cell cycle machinery at discrete stages of hematopoietic differentiation and during cytokine-mediat
73 ion that culminates in a failure of terminal hematopoietic differentiation and emphasizes the role of
74 dynamics, which are tightly regulated during hematopoietic differentiation and enable cell type-speci
76 MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignan
77 Stat5 plays a key role in the regulation of hematopoietic differentiation and hematopoietic stem cel
78 nulocyte-specific genes that are involved in hematopoietic differentiation and inhibitor of different
82 in cultured AGM cells significantly induces hematopoietic differentiation and loss of the progenitor
83 rstanding novel regulatory circuits in early hematopoietic differentiation and malignant transformati
84 ient and mouse hematopoietic cells and alter hematopoietic differentiation and maturation in animal m
86 d changes in this compartment that impact on hematopoietic differentiation and mobilization of a vari
87 y that contributes to cytokine regulation of hematopoietic differentiation and offer a potential mech
88 atin, RNA and surface proteins during native hematopoietic differentiation and peripheral blood monon
90 tential mechanisms for stromal inhibition of hematopoietic differentiation and possibly for the poor
91 shown that this oncoprotein interferes with hematopoietic differentiation and proliferation and part
92 trong evidence that miRNAs modulate not only hematopoietic differentiation and proliferation but also
93 r fumarate metabolism in HSC maintenance and hematopoietic differentiation and reveal a differential
94 ineage commitment to facilitate multilineage hematopoietic differentiation and thus identify their no
95 figuration of the chromatin landscape during hematopoietic differentiation and to uniquely identify C
96 sed as a template for the integration of new hematopoietic differentiation and transdifferentiation d
97 op highly penetrant, multilineage defects in hematopoietic differentiation and, with advancing age, a
98 nvolving transcription factors important for hematopoietic differentiation and/or signaling molecules
99 evaluated ESC-derived LKS cells for in vitro hematopoietic-differentiation and colony formation (CFU
100 n factors that function in immune responses, hematopoietic differentiation, and cell growth regulatio
101 IDH1 and IDH2 affect the leukemia epigenome, hematopoietic differentiation, and clinical outcome.
102 apacity for unlimited self-renewal, impaired hematopoietic differentiation, and enhanced proliferatio
103 inding factor (CBF), resulting in a block of hematopoietic differentiation, and induces leukemia upon
104 sG12D palmitoylation in signal transduction, hematopoietic differentiation, and myeloid transformatio
105 ll cycle control, DNA repair, cell division, hematopoietic differentiation, and near many ESTs and no
106 bin expression, define mechanisms regulating hematopoietic differentiation, and probe the pathogenici
107 istribution, regulation of expression during hematopoietic differentiation, and subcellular localizat
108 ata show that DNAme shapes the topography of hematopoietic differentiation, and support a model in wh
109 iption factors, which play a pivotal role in hematopoietic differentiation, and their inappropriate e
110 whereas CREBBP is essential for neurulation, hematopoietic differentiation, angiogenesis and skeletal
111 conjugated monoclonal antibodies that target hematopoietic differentiation antigens have been develop
112 oiesis in which many of the genes specifying hematopoietic differentiation are expressed by HSPCs, bu
113 by their expression of genes associated with hematopoietic differentiation, as well as morphologic as
115 Projection of the ALL cells along the normal hematopoietic differentiation axis revealed a diversity
120 omprises three major steps: (i) induction of hematopoietic differentiation by coculture of hPSCs with
121 hat RUNX1 exists as a monomer that regulates hematopoietic differentiation by interacting with tissue
122 rescence Cre reporter allele, largely normal hematopoietic differentiation capacity of Hdac8-deficien
123 utations, we generated iPSC lines that, upon hematopoietic differentiation, capture distinct premalig
124 ls, we observed that these mutations disrupt hematopoietic differentiation, causing opposite shifts i
125 s in heterologous genes; and (v) ES in vitro hematopoietic differentiation coupled with regulated BCR
127 differentiation, suggesting that AME induces hematopoietic differentiation defects through at least t
128 machine learning to derive a model of human hematopoietic differentiation directly from DNA methylat
129 y single-sample and single-cell inference of hematopoietic differentiation establishes five robust in
132 clusters that suggest novel hypotheses about hematopoietic differentiation-for example, highlighting
133 s in cellular reprogramming technologies and hematopoietic differentiation from human pluripotent ste
134 ild-type FLT3 (FLT3-WT) completely abrogates hematopoietic differentiation from MLL-AF4-expressing hE
135 ad is necessary for normal activation of the hematopoietic differentiation gene serpent in the same a
139 transcriptional inactivation of HOXA9 during hematopoietic differentiation has been established, litt
140 tic manipulation of intrinsic factors during hematopoietic differentiation has proven a suitable appr
141 lineage restriction from HSCs, this model of hematopoietic differentiation has recently been challeng
143 Leukemia can arise at various stages of the hematopoietic differentiation hierarchy, but the impact
144 he percentage of pig-a- embryoid bodies with hematopoietic differentiation, however, were significant
145 itted progenitors are mostly associated with hematopoietic differentiation, immune regulation, and me
146 population during human embryonic stem cell hematopoietic differentiation in a Notch-dependent manne
148 wever, the transcriptomic networks governing hematopoietic differentiation in blood cell development
149 of such analysis, the approach is applied to hematopoietic differentiation in four well studied model
151 pathway genes at critical stages of myeloid hematopoietic differentiation in LCH patients supports r
154 manifest deficits in exocrine pancreatic and hematopoietic differentiation in vitro, enhanced apoptos
155 ly, telomerase-mutant iPSCs showed defective hematopoietic differentiation in vitro, mirroring the cl
156 ng the splicing factor SRSF2 directly impair hematopoietic differentiation in vivo, which is not due
159 support a model whereby ASB2 contributes to hematopoietic differentiation, in part, through MLL degr
160 populations isolated at different stages of hematopoietic differentiation, including mesoderm, hemog
161 er binding proteins (C/EBPs) are involved in hematopoietic differentiation, including myelopoiesis an
162 of transcription factors with known roles in hematopoietic differentiation, including Pax5 and Ebf1 f
163 tion of NOD1 in a human system of definitive hematopoietic differentiation indicates functional conse
169 s participate in B lymphopoiesis and whether hematopoietic differentiation is skewed toward specific
170 transcription factors are known to regulate hematopoietic differentiation, major aspects of the glob
173 fforts are directed toward adapting in vitro hematopoietic differentiation methods developed for muri
174 e frequency of mutated cells increased along hematopoietic differentiation mimicking the clonal expan
176 e assays and modulates its ability to induce hematopoietic differentiation of hematopoietic cell line
178 -function studies reveal that HOXA9 enhances hematopoietic differentiation of hESCs by specifically p
179 ulating factor CDX4 These data indicate that hematopoietic differentiation of hESCs models the earlie
182 choices and gene expression patterns during hematopoietic differentiation of hPSCs and showed that o
185 In this paper, we describe a protocol for hematopoietic differentiation of human pluripotent stem
186 by deacetylation appears to be important for hematopoietic differentiation of induced pluripotent ste
188 ase that catalyzes LPA production, inhibited hematopoietic differentiation of mouse embryonic stem ce
189 upplemented with cytokines was developed for hematopoietic differentiation of rhesus monkey embryonic
191 id elf-1-like factor/ELF4-deficient mice) or hematopoietic differentiation (p21- and p27-deficient mi
192 g HSC engraftment, and interrogating in vivo hematopoietic differentiation pathways and mechanisms re
193 y, we performed integration analyses between hematopoietic differentiation performance and molecular
194 transcription reprogramming associated with hematopoietic differentiation poses a major threat to ge
198 ontaining proto-oncogene TLX1/HOX11 inhibits hematopoietic differentiation programs in a number of mu
200 formation in an embryonic stem cell model of hematopoietic differentiation provided biological eviden
201 itively regulates expression of mesoderm and hematopoietic differentiation-related factors, including
202 further demonstrate a marked enhancement of hematopoietic differentiation relative to wild-type hESC
205 find that reprogramming transcription during hematopoietic differentiation results in an overload of
208 ion of Hox genes, resulting in a blockage of hematopoietic differentiation that ultimately leads to l
210 raction Database pointed to miRNA control of hematopoietic differentiation through translational cont
211 strate that SHP-1 acts at multiple stages of hematopoietic differentiation to alter lineage balance.
214 andscape and gene expression dynamics during hematopoietic differentiation using DNase-seq, histone m
216 isogenic trisomic counterparts, but in vitro hematopoietic differentiation was not consistently alter
217 igate the specificity of cytokine signals in hematopoietic differentiation, we generated mice with a
218 vestigate the role of GPI-linked proteins in hematopoietic differentiation, we have inactivated the p
219 tumor suppressors and genes associated with hematopoietic differentiation were repressed at later ti
220 ginally affected T-lineage specification and hematopoietic differentiation with a slight increase in
221 loid leukemia (AML) are diseases of abnormal hematopoietic differentiation with aberrant epigenetic a
223 alance can lead to hematopoietic failure, as hematopoietic differentiation without self-renewal leads