ライフサイエンスコーパス: hematuria

1 ons, and urologic procedures to manage gross hematuria).

2 nephrosis requiring nephrostomy due to gross hematuria).

3 me, 68% had renal insufficiency, and 77% had hematuria.

4 s with persistent, asymptomatic, microscopic hematuria.

5 rtion of patients with persistent glomerular hematuria.

6 osis and management of persistent glomerular hematuria.

7 ons typically cause isolated, nonprogressive hematuria.

8 lify the imaging evaluation of patients with hematuria.

9 l subjects and in four of five patients with hematuria.

10 the characteristic presentation of painless hematuria.

11 cluded proteinuria, renal insufficiency, and hematuria.

12 urinary tract infections, renal stones, and hematuria.

13 f AKI, including proteinuria with or without hematuria.

14 isodes of microscopic or gross nonglomerular hematuria.

15 cant association was not observed in case of hematuria.

16 pients who present with gross or microscopic hematuria.

17 ht patients presented with fever and ten had hematuria.

18 nted with nephrotic syndrome and microscopic hematuria.

19 rular damage and more severe proteinuria and hematuria.

20 ation significantly reduced the incidence of hematuria.

21 ted with a significantly lower risk of gross hematuria.

22 sent with nephrotic syndrome and microscopic hematuria.

23 were not previously identified in a GWAS of hematuria.

24 y reported AE being asymptomatic microscopic hematuria.

25 ceeded that of ANCA titers, proteinuria, and hematuria.

26 gic procedure to investigate or manage gross hematuria.

27 hematuria and those with negative or minimal hematuria.

28 ancer detection in the initial evaluation of hematuria.

29 ions for clinicians evaluating patients with hematuria.

30 oscopic hematuria about any history of gross hematuria.

31 ted free light chain ratio, proteinuria, and hematuria.

32 ant proportions and may present with massive hematuria.

33 families, respectively) and benign familial hematuria.

34 ing, or infected stone causing pain or gross hematuria.

35 department due to right-sided flank pain and hematuria.

36 pack-year history of smoking developed gross hematuria.

37 although without significant proteinuria or hematuria.

38 nclude Alport's syndrome and benign familial hematurias.

39 32.6% of patients have hematuria, 15.2% have leukocyturia and 7.8% have both.

40 =3 bleeding events in >/=2% of patients were hematuria (2%) and subdural hematoma (2%).

41 on (UTI), 8; gross hematuria, 5; microscopic hematuria, 2; dysuria without infection, 6; difficulty v

42 loped renal-related complications, including hematuria (24 patients), urinoma (15 patients), urinary

43 opsy-confirmed IgAN with kidney C3 deposits, hematuria, 24-hour proteinuria above 1.5 g/day, and eGFR

44 left abdomen for one month and an episode of hematuria 3 days earlier accompanied by an attack of acu

45 ethritis and extravasation (7%), and chronic hematuria (3%).

46 7), bacterial urinary tract infection (3/7), hematuria (3/7), cytomegalovirus infection (3/7), and im

47 turia than patients with minimal or negative hematuria (30.4% and 37.0% versus 10.6% and 15.2%, respe

48 93, P = .04), driven primarily by reports of hematuria: 4.3% (bevacizumab), 0.7% (sham), 0.2% (aflibe

49 were urinary tract infection (UTI), 8; gross hematuria, 5; microscopic hematuria, 2; dysuria without

50 redictors were 15.6% (15 of 96 patients) for hematuria, 6.0% (13 of 216) for lower rib fractures, 7.6

51 ta on 21 patients showed proteinuria (100%), hematuria (75%), kidney insufficiency and nephrotic synd

52 (-66%+/-2%), percentage of participants with hematuria (-75%; 95% confidence intervals, -87 to -59; i

53 Sixty of the 73 patients with nonglomerular hematuria (82%) had cystoscopy at the NIH.

54 e gut, elevated serum IgA levels, and severe hematuria, a hallmark of IgAN.

55 ecifically ask all patients with microscopic hematuria about any history of gross hematuria.

56 adder stones, blockage, false passage, gross hematuria, accidental removal, urine leakage, or urethra

57 ric hematomas accounting for 13.4% and gross hematuria accounting for 2.7%.

58 nce therapy, serum creatinine and persistent hematuria after induction, a UPCR of 0.05 g/mmol or more

59 ominal hemorrhage and one case each of gross hematuria, allograft pancreatitis, and severe pain requi

60 ography was higher in patients evaluated for hematuria alone (98%, 589 of 603).

61 ith SCI, 13.5% (CI, 3.4% to 21.9%) had gross hematuria and 1.0% (CI, 0.0% to 5.0%) developed bladder

62 Overall, we identified 2.9% of patients with hematuria and 1.0% with proteinuria during a median foll

63 tion therapy, 157/526 (29.8%) had persistent hematuria and 165/481 (34.3%) had UPCR of 0.05 g/mmol or

64 cystoscopy was performed in 13 patients with hematuria and abnormal findings at conventional cystosco

65 e diagnosed by renal biopsy in patients with hematuria and adenoviruria.

66 Overall, GWAS for the composite trait of hematuria and albuminuria identified 4 loci, 2 of which

67 Thus the composite trait of hematuria and albuminuria was chosen to enrich for glome

68 of lymphoma was the sudden onset of painless hematuria and ARF is described.

69 no significant comorbidities presented with hematuria and dysuria.

70 Hematuria and fracture of the lower ribs, lumbar spine,

71 opathies invariably present with microscopic hematuria and frequently progress to proteinuria and CKD

72 cycline-treated C57BL/6 x SJL mice developed hematuria and glomerulonephritis on the MR and standard

73 Children with microscopic hematuria and no evidence of multiple system trauma seem

74 = 13; 32.5%), pollakiuria (n = 11; 28%), and hematuria and nocturia (n = 10 each; 25%).

75 At 1,000 mg, three patients developed hematuria and one had a skin reaction resembling grade 3

76 ry clinical manifestations of this disorder, hematuria and papillary necrosis, are discussed.

77 s (questions and answers) on 5 urology CPGs (hematuria and priapism [HP]; staghorn calculi, infertili

78 re age 1 year, have persistent hypertension, hematuria and proteinuria (sometimes in the nephrotic ra

79 antibody (ANCA)-associated vasculitis (AAV), hematuria and proteinuria are biomarkers reflecting kidn

80 The majority of patients had hematuria and proteinuria at time of recurrence.

81 Children with combined hematuria and proteinuria had a higher prevalence of sig

82 cal examination should indicate the cause of hematuria and proteinuria in most cases.

83 The review will discuss the major causes of hematuria and proteinuria in the pediatric population, a

84 The presence of hematuria and proteinuria together significantly increas

85 Despite reports of hematuria and proteinuria with rosuvastatin use at the t

86 ategories and evaluated for a dose effect on hematuria and proteinuria.

87 per tract imaging depending on the degree of hematuria and risk of malignancy.

88 ticle describes the clinical epidemiology of hematuria and the current state of practice and science

89 classified patients as those with persistent hematuria and those with negative or minimal hematuria.

90 ipstick: glucosuria, ketonuria, proteinuria, hematuria and urine pH.

91 h sickle cell trait who presented with gross hematuria and was subsequently found to have renal papil

92 high-risk group according to the presence of hematuria and/or axial fracture on radiographs.

93 d with 86-24 Stm(r) or B2F1 Stm(r) developed hematuria and/or histological damage to glomeruli or thr

94 l pelvis with calculus increases the risk of hematuria and/or hydronephrosis, presenting with colicky

95 inal outcome of examination of children with hematuria and/or proteinuria.

96 on of this in cases of otherwise unexplained hematuria), and human immunodeficiency virus-associated

97 s, -87 to -59; in participants with baseline hematuria), and UPCR (-52%+/-5%).

98 urine studies, 84% had proteinuria, 81% had hematuria, and 60% had leukocyturia.

99 toms of infection and denied fever, dysuria, hematuria, and abdominal pain.

100 et of hypertension, early and frequent gross hematuria, and among women, three or more pregnancies.

101 Proteinuria >=1.5 g/d, hematuria, and an elevated free light chain ratio increa

102 ondary to a combination of thrombocytopenia, hematuria, and anemia that required transfusion.

103 body levels, the presence of proteinuria and hematuria, and by histopathologic analysis of kidney tis

104 Prodromal symptoms included fever, hematuria, and flank pain.

105 a history of acute urinary retention, gross hematuria, and left flank pain for 2 days.

106 sent with normal renal function, microscopic hematuria, and minimal or no proteinuria is not well des

107 uding hearing loss, intellectual disability, hematuria, and orofacial clefting.

108 e resulted in the resolution of proteinuria, hematuria, and PKD.

109 complexes resulting in kidney inflammation, hematuria, and proteinuria, mice expressing IgA1 only di

110 ing renal flares, outperforming ANCA titers, hematuria, and proteinuria.

111 Therefore, the prevalence of proteinuria, hematuria, and reduced GFR in the Australian adult popul

112 TG who typically presented with proteinuria, hematuria, and renal insufficiency.

113 ociates with impaired urinary concentration, hematuria, and renal papillary necrosis, but its prevale

114 ol level, urinalysis proteinuria, urinalysis hematuria, and serum creatinine level.

115 horesis, serum creatinine, C3 level (mg/dL), hematuria, and systolic blood pressure.

116 uria, the presence of persistent microscopic hematuria, and the rate of eGFR loss, combined with the

117 Atacicept treatment reduced Gd-IgA1, hematuria, and UPCR with stabilization of eGFR through 9

118 cause kidney insufficiency, bladder calculi, hematuria, and urinary tract infections.

119 Leukocytes, hematuria, and urobilinogen concentrations in urine were

120 cities were one episode each of esophagitis, hematuria, and vomiting.

121 ian adult population has either proteinuria, hematuria, and/or reduced GFR, indicating the presence o

122 Patients may have proteinuria, hematuria, and/or renal dysfunction.

123 teinuria; age, gender, and hypertension with hematuria; and age, gender, and hypertension with reduce

124 n causes an astonishing breadth of sequelae: hematuria, anemia, dysuria, stunting, uremia, bladder ca

125 ere thrombocytopenia plus head trauma and/or hematuria appeared to be at particularly high risk of IC

126 forms of urolithiasis, acute flank pain and hematuria are the typical symptoms of indinavir urolithi

127 There was a notable decrease in hematuria, as well as rapid and durable reductions in Ig

128 One of the hematuria-associated variants is a rare, previously unre

129 sappeared in all 5 patients with significant hematuria at baseline.

130 ion rate, or the presence of hypertension or hematuria at the time of diagnosis.

131 ntrols with prior urinary tract infection or hematuria because urinary symptoms resulting in antibiot

132 Similarly, those who had an episode of gross hematuria before age 30 had a worse renal outcome than t

133 Phenotypes examined included dipstick hematuria, bilateral sensorineural hearing loss, protein

134 Pooled rates of gross hematuria, bleeding requiring transfusion, and major com

135 Primary outcomes were gross hematuria, bleeding requiring transfusion, and major com

136 tis experienced complete resolution of gross hematuria by week 6.

137 Hematuria (by dipstick only) occurred in 25 (41%) of 61

138 Moreover, hematuria consistently decreased after treatment.

139 Cases had both hematuria defined by ICD codes and albuminuria defined a

140 72 patients who had never had nonglomerular hematuria developed bladder cancer.

141 rapidly progresses, microthrombi appear, and hematuria develops.

142 After hematuria disappearance, which occurred in 46% of the pa

143 1 month after the last dose (P < 0.005), and hematuria disappeared in all 5 patients with significant

144 or renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splittin

145 acility complaining of weight-loss, fatigue, hematuria, dysuria, painful right inguinal ulceration, a

146 CE 6: Clinicians should pursue evaluation of hematuria even if the patient is receiving antiplatelet

147 urologic evaluation in all adults with gross hematuria, even if self-limited.

148 were influenced primarily by differences in hematuria events, which may be a result of differential

149 Hematuria following radiation therapy for prostate cance

150 9-year-old patient was admitted with massive hematuria following transurethral resection of prostate

151 calculi in his urine after the occurrence of hematuria, following which pain decreased in intensity.

152 laints of breathlessness, abdominal pain and hematuria for the last 6 months.

153 tutions were confirmed to be associated with hematuria (for each, P<0.001).

154 five of 56 (9%) participants and were minor (hematuria, four participants; hematospermia, one partici

155 Recognition that glomerular hematuria frequently has a genetic basis is important fo

156 veraged proteinuria >0.75 g/d and persistent hematuria had significantly worse renal survival than th

157 unodepletion before TGN markedly exacerbated hematuria (hemorrhage), inflammation, and injury, wherea

158 merular defects), microscopic urinalysis for hematuria (hemorrhagic cystitis, bladder cancer), ECG (a

159 Its pathologic features include hematuria, high levels of circulating IgA-fibronectin (F

160 statin was associated with increased risk of hematuria (HR, 1.08; 95% confidence interval [95% CI], 1

161 ected in 2.4% of cases (95% CI: 1.6%, 3.1%), hematuria in 4.6% (95% CI: 3.8%, 5.4%), and reduced GFR

162 arin") increased serum creatinine levels and hematuria in 5/6-nephrectomized rats but not in controls

163 sits and reduces inflammation, fibrosis, and hematuria in a mouse IgAN model, and therefore may be a

164 lpha3alpha4alpha5(IV) network, progress from hematuria in early childhood to proteinuria, chronic kid

165 or assembly of a defective scaffold, causing hematuria in nearly all cases, proteinuria, and often pr

166 els in four patients (6%) and transient mild hematuria in one patient (1%).

167 ve also observed proteinuria and microscopic hematuria in such patients.

168 ing in adults with microscopically confirmed hematuria in the absence of some demonstrable benign cau

169 moking history presented with painless gross hematuria in the fall of 2015 and was ultimately diagnos

170 Our GWAS of hematuria in the UK Biobank identified 6 loci, some of w

171 RE ADVICE 1: Clinicians should include gross hematuria in their routine review of systems and specifi

172 Dose-limiting toxicities included hematuria, increased gamma-glutamyltransferase or ALT, i

173 Hematuria is a cardinal symptom in IgA nephropathy, but

174 Asymptomatic, microscopic hematuria is seen in 8-21% of the general population, ha

175 The presence of blood in the urine, or hematuria, is a common finding in clinical practice and

176 In 13 (36%) of 36 patients, hematuria lasted longer than 24 hours but resolved witho

177 mal electrocardiogram findings, proteinuria, hematuria, low hemoglobin level, elevated erythrocyte se

178 ted liver transaminases (LR range, 2.5-5.2), hematuria (LR range, 3.7-4.1), anemia (LR range, 2.2-3.3

179 In conclusion, remission of hematuria may have a significant favorable effect on IgA

180 he high NPV of CT urography in patients with hematuria may obviate cystoscopy in selected patients.

181 more prominent hypertension and microscopic hematuria may provide clues to the presence of HCV-GD, r

182 cations, including urinary tract infections, hematuria, metabolic acidosis, dehydration, and reflux p

183 lated complications defined as pain, visible hematuria, migration, fragmentation, and urinary tract i

184 of hypothetical predictors of missed injury: hematuria (n = 96) or fracture of the sixth through 12th

185 Infection and hematuria need to be ruled out.

186 ectively, had renal hematoma and macroscopic hematuria; none required any specific treatment.

187 maging, prior suspected stone episode, gross hematuria, nonobstructing (asymptomatic) stone on imagin

188 Controls had neither an ICD code for hematuria nor an uACR > 3 mg/mmol.

189 Nonglomerular hematuria occurred in 73 of 145 patients treated with cy

190 y fever, myalgias, pruritus, and proteinuria/hematuria, occurred in 83% vs 50% of those receiving tri

191 Urine protein-creatinine ratio (UPCR) and hematuria of spot urine samples collected at the end of

192 ling catheter drainage and two patients with hematuria, one of whom required overnight bladder irriga

193 , on further classification by time-averaged hematuria, only those patients with time-averaged protei

194 6 years, range of 18-86 years) evaluated for hematuria or a history of urothelial cancer, who had und

195 Fifty-one patients with hematuria or a suspicious renal mass underwent CT urogra

196 ing a similar protocol, no animals developed hematuria or glomerulonephritis, despite having identica

197 Most children with either isolated hematuria or isolated proteinuria had benign disease pro

198 od urea nitrogen, creatinine, bleeding time, hematuria or proteinuria, and aspartate aminotransferase

199 is indicated by the presence of proteinuria, hematuria, or reduced GFR.

200 (PCPs) for CT evaluation of abdominal pain, hematuria, or weight loss were identified.

201 In patients with abdominal pain, hematuria, or weight loss, leading diagnoses changed aft

202 continued to have asymptomatic, microscopic hematuria over 1 month.

203 ptoms: pain (P < .001), shivers, (P = .020), hematuria (P < .001), hematochezia (P < .001), and hemoe

204 iopsies, with choices limited to none, gross hematuria, perinephric hematoma, and other.

205 e Lama5(neo) allele) results in proteinuria, hematuria, polycystic kidney disease (PKD), and death 3

206 teriorate within 3-6 days, with oliguria and hematuria progressing to anuria, and the kidneys were ex

207 ome is an inherited disease characterized by hematuria, progressive renal failure, hearing loss, and

208 At presentation, hematuria, proteinuria >/=1 g/d, hypertension, and renal

209 statin was associated with increased risk of hematuria, proteinuria, and KFRT.

210 of treatment-weighted hazard ratios (HRs) of hematuria, proteinuria, and kidney failure with replacem

211 ather, homozygous mutant mice had glomerular hematuria, proteinuria, and podocytopathy.

212 uating renal inflammation, using microscopic hematuria, proteinuria, estimated glomerular filtration

213 2.0 microg/kg; n = 5) to renal failure with hematuria, proteinuria, thrombocytopenia, schistocytosis

214 Gross hematuria rates were lower in high-income compared with

215 ignificantly associated with higher rates of hematuria-related complications (including emergency dep

216 To characterize rates of hematuria-related complications among patients taking an

217 median follow-up of 7.3 years, the rates of hematuria-related complications were 123.95 events per 1

218 unexposed to thrombotic agents, the rates of hematuria-related complications were 191.61 events per 1

219 Hematuria-related complications, defined as emergency de

220 The previous GWAS of hematuria reported COL4A3-COL4A4 variants and HLA-B*0801

221 Hematuria resolved after insertion of a 3-way urinary ca

222 In two prospective donors, hematuria resolved after treatment for urinary tract inf

223 The hematuria resolved with conservative therapy consisting

224 wn markers, including long-term follow-up of hematuria screening, recent studies in DNA methylation f

225 creatinine ratio (abnormal: >/=0.20 mg/mg); hematuria-spot urine dipstick (abnormal: 1+ or greater)

226 The hematuria stopped after 1 week.

227 , increases C3 concentrations, and decreases hematuria, suggesting that the drug has immunomodulatory

228 s C), rigors, malaise, lethargy, flank pain, hematuria, suprapubic discomfort, dysuria, and urgent or

229 antly greater among patients with persistent hematuria than patients with minimal or negative hematur

230 One patient developed hematuria that required transfusion but no further inter

231 nic thrombotic microangiopathy together with hematuria, thrombocytopenia, elevated creatinine, and ev

232 ultivariable analysis revealed time-averaged hematuria, time-averaged proteinuria, renal function at

233 , and bladder--and thus allows patients with hematuria to be evaluated comprehensively.

234 nical manifestations range from asymptomatic hematuria to progressive chronic kidney disease (CKD), w

235 e), transaminase elevation (one course), and hematuria (two courses).

236 dominal/right upper quadrant gunshots and/or hematuria underwent mandatory CT with intravenous contra

237 the sensitivity or specificity of tests for hematuria, urinary cytology, or other urinary biomarkers

238 BKV-HC typically results in painful hematuria, urinary obstruction, and renal dysfunction, w

239 1 (Gd-IgA1), percentage of participants with hematuria, urine protein-creatinine ratio (UPCR), and eG

240 th a range of clinical presentations such as hematuria, voiding dysfunction, flank pain, abdominal pa

241 13 of 100 cycles and grade 3/4 hemorrhage or hematuria was 2%; the platelet transfusion rate was four

242 Nonglomerular hematuria was a frequent manifestation of cyclophosphami

243 s showed that only microscopic nonglomerular hematuria was a significant risk factor for the developm

244 ilure and kidney relapse, whereas persistent hematuria was an independent predictor of kidney relapse

245 Persistent hematuria was associated with significant kidney relapse

246 Hematuria was common among both diabetics and nondiabeti

247 other relevant studies on the evaluation of hematuria was conducted, with particular emphasis on con

248 Among nondiabetics, however, hematuria was more common among women.

249 uminuria, although the degree of microscopic hematuria was reduced by this intervention.

250 Gross hematuria was reported in six patients (2.8%): two SB (2

251 of 11 placebo recipients, although no gross hematuria was reported.

252 Among diabetics, the crude prevalence of hematuria was similar among men and women.

253 Hematuria was the first tumor marker in a field that has

254 According to the magnitude of time-averaged hematuria, we classified patients as those with persiste

255 Proteinuria and hematuria were frequent in both groups but more common i

256 Febrile neutropenia, diarrhea, and hematuria were more frequent with C25; peripheral neurop

257 xplained renal dysfunction, proteinuria, and hematuria were retrospectively reviewed.

258 Head trauma and hematuria were the most prominent features associated wi

259 tumors can present with gross or microscopic hematuria, which is evaluated with cystoscopy and upper

260 ns included renal insufficiency, microscopic hematuria with active urine sediment, hypertension, and

261 gs: reduced kidney function, proteinuria, or hematuria with other causes excluded (n = 2).

262 ar-old female with TSC presenting as massive hematuria with underlying giant bilateral renal angiomyo

263 patient with HIV who presented with AKI and hematuria without concomitant systemic manifestations.