ライフサイエンスコーパス: heme iron

1 resulting thiol coordinating to the cofactor heme iron.

2 a key cysteine residue that coordinates the heme iron.

3 sient iron-oxo (ferryl) intermediates of the heme iron.

4 e insight into how L. monocytogenes captures heme iron.

5 matic hydrocarbons, N-nitroso compounds, and heme iron.

6 yl substituent oriented toward the catalytic heme iron.

7 ated with O2 stably bound to the active site heme iron.

8 al damage during ischemia, by protecting its heme iron.

9 HCCS (His154) provided the key ligand to the heme iron.

10 nce on the amount of fat and the contents in heme iron.

11 NO via coordination to and release from the heme iron.

12 maps with its pyridyl nitrogen bound to the heme iron.

13 conserved Leu residue near the catalytic non-heme iron.

14 eme peroxidases that have a histidyl-ligated heme iron.

15 ay beam reveal photoreduction of the central heme iron.

16 lete binding of several azoles to the BM3 DM heme iron.

17 nes in the heme pocket directly bound to the heme iron.

18 as indicative of nitrogenous ligation to the heme iron.

19 ein with pentacoordinate, methionine-ligated heme iron.

20 lotrimazole being at a 4 A distance from the heme iron.

21 with those of proteins with pentacoordinate heme iron.

22 ual heterocyclic amines, benzo(a)pyrene, and heme iron.

23 s utilized by Mtb to acquire ferric iron and heme iron.

24 dence for this site being used to access the heme iron.

25 by permanent displacement of Met80 from the heme iron.

26 gaseous ligands through coordination to the heme iron.

27 ed oxygenic ligand at 1.88 angstrom from the heme iron.

28 without loss of the native low spin type of heme iron.

29 presumed to be subsequently captured by the heme iron.

30 The relative part of heme iron (1% in diet), heterocyclic amines (PhIP + MeIQ

31 achlorhydria reduced the normal increase in heme-iron absorption from hemoglobin in response to iron

32 The magnitude of the decrease in heme-iron absorption is greater than that of nonheme iro

33 Heme-iron absorption was 23.9% before and 6.2% 12 mo aft

34 In addition, hemolysis and macrophage heme/iron accumulation in a mouse model of sickle diseas

35 egulation and localization for the S. aureus heme iron acquisition system.

36 rophore-mediated iron acquisition (SMIA) and heme-iron acquisition (HIA), involving uptake and degrad

37 of bacterial proliferation independently of heme-iron acquisition by pathogens.

38 odel for Isd-mediated hemoglobin binding and heme-iron acquisition during the pathogenesis of S. aure

39 202c-Rv0207c, responsible for the passage of heme iron across the mycobacterial membrane.

40 zation of AmbO5 protein as a promiscuous non-heme iron aliphatic halogenase.

41 -C2 carbocyclization is catalyzed by the non-heme iron alpha-ketoglutarate (alpha-KG)-dependent SnoK

42 yl 4-hydroxylases (P4Hs) are mononuclear non-heme iron alpha-ketoglutarate (alphaKG)-dependent dioxyg

43 a mechanistically distinct bifunctional non-heme iron alpha-ketoglutarate-dependent enzyme responsib

44 or threonine residue, the inclusion of a non-heme iron, alpha-ketoglutarate-dependent oxygenase for h

45 and distal histidines directly bound to the heme iron, although coordination of the sixth ligand is

46 ter molecule that is coordinated to the P450 heme iron and also hydrogen-bonded to the BIC nitrile.

47 ron uptake mechanisms, one that utilizes non-heme iron and another that taps into the vast host heme-

48 ed to observed structural changes in the non-heme iron and catalytic sites.

49 an intrinsic ability to reduce oxidized sGC heme iron and form protein-protein complexes between cyt

50 ct tertiary structure with a hexacoordinated heme iron and functions in electron transport in mitocho

51 in, dietary cholesterol, saturated fats, and heme iron and higher urinary potassium and intakes of ca

52 e resulting breakage of the bond between the heme iron and histidine 105 (H105) of the beta subunit o

53 guides incoming hydrogen peroxide toward the heme iron and mediates proton rearrangement in the proce

54 is highly homologous to human SO (HSO), the heme iron and molybdenum centers are separated by 32 A a

55 ther ligand interaction often occurs between heme iron and native methionine ligands, but thioether-b

56 nt implications on electronic charge of both heme iron and O2 , resulting in increased O2 dissociatio

57 leads to the rupture of the bond between the heme iron and the intrinsic sulfur ligand of a methionin

58 nger coordination bond between the catalytic heme iron and the pyridine nitrogen implies a weaker inf

59 ing function by modulating bonding between a heme iron and the sulfur in a methionine residue.

60 (His19) of CXXCH acts as an axial ligand to heme iron and upon release of holocytochrome c from HCCS

61 gen atom of mycinamicin IV within 6 A of the heme iron and ~4 A of the oxygen of iron-ligated water.

62 The c-type heme irons and the nascent TTQ site are separated by lon

63 out a different bond interaction between the heme-iron and the proximal histidine and highlighting st

64 on, irreversible type II coordination to the heme iron, and more recently heme destruction.

65 GDM, greater intakes of total iron, dietary heme iron, and supplemental iron were associated with hi

66 e nitrogen atom of 24 to coordinate with the heme iron, and the imidazoleisoindole core situated in p

67 as evaluated in the reaction of nitrite with heme iron, and the observed rate constants of the reacti

68 (M80) and second-sphere (Y67) ligands of the heme iron, as a distinctive feature of the conformationa

69 ly correlated to the electron density at the heme iron, as evidenced by dramatic changes in the heme

70 by the slow dissociation of Cys-52 from the heme iron, as reported for CO.

71 n active-site base or by oxygen bound to the heme iron, as the initial step.

72 itors described so far, does not bind to the heme iron atom and has a novel binding mode.

73 robably dioxygen) was sandwiched between the heme iron atom and Thr237 in the TxtC-intermediate struc

74 ) bond or alternatively the oxidation of the heme iron atom itself is used to detect O(2) and switch

75 e of the cysteines stably coordinates to the heme iron atom.

76 face of the phenyl group positioned over the heme iron atom.

77 , was found to contain two tightly bound non-heme iron atoms per protein monomer.

78 ighest binding affinity to heme and controls heme-iron availability in tissues and also in T lymphocy

79 me c(2), like the heme ligating cysteines or heme iron axial ligands, are less crucial.

80 Heme iron, barbecued/grilled meat, and benzo[a]pyrene we

81 FMN) serves as the one-electron donor to the heme iron, but in contrast to the electron transfer mech

82 issociation of the proximal histidine of the heme iron, but the added peripheral glutamate side chain

83 Trp complex, where CO is photolyzed from the heme iron by X-rays at cryogenic temperatures (100 K).

84 lu, suggest that water displacement from the heme iron can be affected in activator-bound CYP46A1.

85 tion of the distal histidine relative to the heme iron can influence reactivity at the heme center.

86 We report a simple small-molecule, non-heme iron catalyst that achieves predictable catalyst-co

87 structurally simpler oxidants, including non-heme iron catalysts Lambda-2 and Lambda-2SbF(6).

88 nt strategies were assessed for avoiding the heme iron catalytic effect on lipid oxidation: ascorbyl

89 the proximal histidine dissociates from the heme iron, causing a conformational change that triggers

90 The non-heme iron center allows for facile modification of the p

91 cyanide (CN(-)), and histamine to the ferric heme iron center in the NO-storage and -transport protei

92 center in AbCntA-WT to the mono-nuclear, non-heme iron center through the bridging glutamate E205 and

93 Typically, these enzymes utilize a non-heme iron center to oxidatively cleave a carbon-carbon d

94 le interactions between paramagnetic FMN and heme iron centers in the [Fe(III)][FMNH(*)] (FMNH(*): FM

95 Cytochrome P450 enzymes activate oxygen at heme iron centers to oxidize relatively inert substrate

96 ge during the course of O2 activation at non-heme iron centers.

97 mately 0.8 A, respectively, farther from the heme iron compared to that in the wild-type protein.

98 s in C-H hydroxylations catalyzed by the non-heme iron complex Fe(PDP).

99 A non-heme iron complex that catalyzes highly enantioselective

100 RR spectra that represent a pentacoordinate heme iron complex with a methionine axial ligand.

101 fold binds and senses environmental O2 via a heme iron complex.

102 Porphyrin, porphyrinoid and non-heme iron complexes are discussed by analyzing experimen

103 oxidations are catalysed by bio-inspired non-heme iron complexes using hydrogen peroxide as oxidant,

104 Non-heme iron complexes with cis-Fe(III)(OH)(SAr/OAr) coordi

105 ternary ammonium substrate, carnitine by non-heme iron containing Acinetobacter baumannii (Ab) oxygen

106 Flavo-diiron proteins (FDPs) are non-heme iron containing enzymes that are widespread in anae

107 Natural fusions between the non-heme iron containing PDO and rhodanese, a thiol sulfurtr

108 otenoid cleavage dioxygenases (CCDs) are non-heme iron-containing enzymes found in all domains of lif

109 lyl hydroxylase domain (PHD) enzymes are non-heme, iron-containing dioxygenases requiring for activit

110 SORs are non-heme, iron-containing enzymes that can catalyze the redu

111 The non-heme iron content both in the renal cortex and medulla o

112 III) derivative of NP4 demonstrates that the heme iron coordinates the first substrate nitrite.

113 The heme iron coordinating residue Y134 proved to be strictl

114 ze of the domain and the lack of a conserved heme iron-coordinating residue.

115 119 from Sulfolobus acidocaldarius maintains heme iron coordination through the introduced ligand, an

116 duction and in regulating protein stability, heme iron coordination, and spin state.

117 rophobic interactions, hydrogen bonding, and heme iron coordination.

118 of colon cancer by red meat and suggest that heme iron could initiate carcinogenesis through lipid pe

119 s to both CYP11B enzymes by coordinating the heme iron, CYP11B2 binds to the R enantiomer of fadrozol

120 Methylphosphonate synthase is a non-heme iron-dependent oxygenase that converts 2-hydroxyeth

121 The plant non-heme iron dioxygenase flavonol synthase performs a regio

122 The non-heme iron domain is located in the monooxygenase, ndmC,

123 is unusual, in that the iron-sulfur and non-heme iron domains that compose the normally functional R

124 Investigation of the heme iron dynamics in cytochrome c with Mossbauer spectr

125 omerism of the Fe(IV)-oxo species in the non-heme iron enzyme catalysis.

126 thesis, the combination of a mononuclear non-heme iron enzyme catalyzed oxidative C-S bond formation

127 ave been proposed for alpha-KG-dependent non-heme iron enzyme catalyzed oxygen atom insertion into an

128 The non-heme iron enzyme cysteine dioxygenase (CDO) catalyzes th

129 In mammals, the non-heme iron enzyme cysteine dioxygenase (CDO) helps regula

130 The non-heme iron enzyme phenylalanine hydroxylase from Chromoba

131 oxidase (HppE) is an unusual mononuclear non-heme iron enzyme that catalyzes the oxidative epoxidatio

132 as savastanoi ethylene-forming enzyme, a non-heme iron enzyme, can catalyze olefin aziridination and

133 As the first high-valent non-heme-iron enzyme complex to be identified and the key ac

134 igh-spin Fe(III)-peroxo intermediates of non-heme iron enzymes may be promoted.

135 ent dioxygenases are a diverse family of non-heme iron enzymes that catalyze various important oxidat

136 cifically, alpha-ketoglutarate-dependent non-heme iron enzymes, CitB and ClaD, are employed to select

137 (II) ion and forms the catalytic site of non-heme iron enzymes.

138 to be kinetically competent oxidants in non-heme iron enzymes.

139 fur clusters and the metallation of some non-heme iron enzymes.

140 scription factors and direct sensing via non-heme iron(Fe(2+))-dependent-dioxygenases.

141 thase (NOS) requires electrons to reduce the heme iron for substrate oxidation.

142 ed D-lactate into pyruvate by converting the heme iron from Fe(3+) to Fe(2+) in a FAD-dependent manne

143 n of peroxides with peroxidases oxidizes the heme iron from Fe(III) to Fe(IV)=O and a porphyrin or ar

144 s fulfills its iron requirement by obtaining heme iron from host hemoproteins via IsdG- and IsdI-medi

145 n to serve as axial ligands that protect the heme iron from oxidation.

146 rIDO by inducing a transition of the ferric heme iron from the predominantly high- to low-spin form

147 ace determinant (Isd) system, which extracts heme-iron from host hemoglobin during infection and is c

148 d surface determinant (Isd) system scavenges heme-iron from the human host, enabling acquisition of i

149 ition for SyrB2, a member of a family of non-heme iron halogenases and hydroxylases that are only rea

150 The non-heme iron halogenases CytC3 and SyrB2 catalyze C-H bond

151 -Fe(III)(OH)(halide) intermediate in the non-heme iron halogenases were synthesized and examined for

152 OleTJE heme iron has an unusually positive redox potential (-10

153 enzymes (P450s whose Cys axial ligand to the heme iron has been replaced with Ser) generated variants

154 Heme iron has many and varied roles in biology.

155 Heme iron, heterocyclic amines, and endogenous N-nitroso

156 onsymbiotic hemoglobin with a hexacoordinate heme iron, high oxygen affinity, and slow oxygen dissoci

157 tential mechanisms for this relation include heme iron (HR, 1.13; 95% CI, 0.99-1.29; P(trend) = 0.022

158 Prolyl-4-hydroxylase (P4H) is a non-heme iron hydroxylase that regio- and stereospecifically

159 Herein, we report a mononuclear non-heme iron(II)-cyclam complex, 1-trans, that activates O(

160 nt knowledge about the properties of the non-heme iron(II)-NO adduct.

161 re and geometric properties of high-spin non-heme iron(II)-NO adducts.

162 IPNS uses a mononuclear non-heme-iron(II) cofactor and dioxygen as cosubstrate to cl

163 -bound and apo-HasA homologues show that the heme iron(III) ligands, His32 and Tyr75, reside on loops

164 viously, Tyr(440) was observed to coordinate heme iron in an IsdB.heme complex structure.

165 onstrating cysteine thiolate coordination of heme iron in both cases.

166 ifferent orientations,and distances from the heme iron in different heme proteins and the position of

167 characterize the regulation of heme and non-heme iron in human failing hearts.

168 i) to provide the second axial ligand to the heme iron in preparation for covalent attachment; (ii) t

169 The accumulation of non-heme iron in the brain has been proposed as a harbinger

170 Heme iron in the ferrous state of this mutant is rapidly

171 These results highlight the role of heme iron in the promotion of colon cancer by red meat a

172 mal epi-isozizaene molecules may bind to the heme iron in two orientations.

173 The structure reveals that the heme irons in each subunit exhibit a rare His/Cys ligati

174 macrophages were exposed to large amounts of heme iron, in contrast to donor and p.A69T macrophages,

175 RATIONALE: Soluble guanylate cyclase (sGC) heme iron, in its oxidized state (Fe(3+)), is desensitiz

176 that the lower affinity of 1,2,3-TRZ for the heme iron includes a large unfavorable entropy term like

177 Heme iron increased the number of preneoplastic lesions,

178 Finally, NHI (non heme iron) increased during refrigerated storage of foal

179 79 residues as the axial ligands of the HtsA heme iron, indicate that the M79 side is more accessible

180 A highly bioavailable heme iron ingredient was selected to fortify a chocolate

181 Heme iron intake increased the risk of lung carcinoma in

182 lung carcinoma, which might be explained by heme iron intake, high-temperature cooking, and associat

183 try, fish, and shellfish intakes, as well as heme iron intake, with the risk of type 2 diabetes melli

184 CI: 1.18, 2.74; P-trend = 0.005) for dietary heme iron intake.

185 ly for poultry and partially for red meat by heme iron intake.

186 .19; 95% CI: 1.05, 1.36; P-trend = 0.06) and heme-iron intake (HR for 1-mg/d increase: 1.83; 95% CI:

187 highest compared with the lowest quintile of heme-iron intake was 1.01 (95% CI: 0.89, 1.14; P for tre

188 o not support an association between iron or heme-iron intakes and postmenopausal breast cancer.

189 es have examined the association of iron and heme-iron intakes with breast cancer risk.

190 Heme iron interaction with HrtR is non-covalent, hexacoo

191 ctra of HtsA with a low-spin, hexacoordinate heme iron into spectra of high-spin heme complexes.

192 pectroscopies indicate that reduction of the heme iron is accompanied by loss of the cysteines as axi

193 Although the absorption of heme iron is poorly understood, nonheme iron is transpor

194 me to IsdA, the final surface protein before heme-iron is transported through the peptidoglycan.

195 n this form, Met80, the native ligand to the heme iron, is replaced by a Lys.

196 of spectroscopically characterized synthetic heme iron(IV) oxo complexes, F(8)Cmpd-II (F(8) = tetraki

197 electronic and geometric structures of these heme iron(IV)-oxo species.

198 s prior to the binding of a second NO to the heme iron, leading to a (six-coordinate low-spin heme-ni

199 d binding to a site near BM3h's paramagnetic heme iron led to a drop in MRI signal enhancement and a

200 red mitochondrial and cytosolic heme and non-heme iron levels in failing human hearts retrieved durin

201 Renal non-heme iron levels were increased in the (New Zealand Blac

202 Although cytosolic non-heme iron levels were reduced in HF, mitochondrial iron

203 er from Hb that involves unfolding of Hb and heme iron ligand exchange.

204 Adjacent to the heme iron ligand, Cys357, is Leu358 in P450cam, whereas

205 as well as the first example of voriconazole heme iron ligation through a pyrimidine nitrogen from it

206 the heme environment upon this switch in the heme iron ligation.

207 Our data demonstrated that Hx prevented heme-iron loading in the cardiovascular system, thus lim

208 of hemoglobin and heme into the circulation, heme-iron loading of reticulo-endothelial system macroph

209 positive charges created upon oxidation of a heme iron (located near the hydrogen bond network) for O

210 Intakes of dietary iron and, in particular, heme iron may increase breast cancer risk because of the

211 amical properties of the axial ligand to the heme iron, Met80, such that the replacement of glycine b

212 Here, we review the impact of macrophages on heme-iron metabolism and, reciprocally, how heme-iron mo

213 oordination of the imidazole nitrogen to the heme iron mimics the position required for native fatty

214 oglobins in having a pentacoordinate ferrous heme iron, moderate oxygen affinity, and a relatively ra

215 heme-iron metabolism and, reciprocally, how heme-iron modulates macrophage function.

216 understanding of the catalytic action of non-heme iron (NHFe) and non-heme diiron (NHFe(2)) enzymes i

217 c amines, polycyclic aromatic hydrocarbons), heme iron, nitrate, and nitrite.

218 processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from

219 nd dietary intake of N-nitrosodimethylamine, heme iron, nitrite, and nitrate in the Netherlands Cohor

220 type, cooking method, and related mutagens), heme iron, nitrite/nitrate, and prostate cancer in a coh

221 ith prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and ben

222 this process, we isolated a new type of non-heme iron nitrosyl complex that is stabilized by an unex

223 model for the key steps leading to these non-heme iron nitrosyl complexes.

224 Two non-heme iron-nitrosyl species, [Fe2(N-Et-HPTB)(O2CPh)(NO)2]

225 To investigate the extent of endogenous heme iron nitrosylation an experimental in vitro model t

226 ion of nitrite (1 mM) considerably increased heme iron nitrosylation while a significant decrease was

227 e previous one by focusing on the endogenous heme iron nitrosylation.

228 The heme iron of cytochromes P450 must be reduced to bind an

229 modified residues of preMADH and the nearest heme iron of MauG is 19.4 A.

230 While (*)NO ligation of the heme iron of soluble guanylate cyclase is consistent wit

231 most convenient for the interaction with the heme iron of the selected cytochromes.

232 ucine abolished the peroxidase activity, and heme iron of the variant showed a pH-dependent transitio

233 Compounds that coordinate to the heme-iron of cytochrome P450 (CYP) enzymes are assumed t

234 After additional adjustment for heme iron, only red meat intake remained significantly a

235 ts of human hemoglobin A (HbA) and modulates heme iron oxidation and subunit folding states.

236 r low-spin) were observed dependent upon the heme iron oxidation state and temperature.

237 the first crystal structure of a Rieske non-heme iron oxygenase that performs an exocyclic monooxyge

238 Non-heme iron oxygenases contain either monoiron or diiron a

239 e active site cysteine that coordinates with heme iron, permitting heme binding and dimerization to t

240 suggested to form an as-yet unobserved bound heme-iron-PN intermediate in the catalytic cycle of nitr

241 ron and another that taps into the vast host heme-iron pool.

242 The substrate-free heme iron potential (-268 mV versus NHE) is positive for

243 l measurements revealed a 155-mV increase in heme iron potential when bound to one of the newly ident

244 ne or in combination with the co-spray-dried heme iron, prevented primary oxidation and hexanal forma

245 teine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes the conversion of cyste

246 Heme (iron protoporphyrin IX) is a well-known prosthetic

247 ormal human brain, proteins, lipids, and non-heme iron provide comparable contributions to tissue pha

248 At low sulfide/heme iron ratios, the product distribution between thios

249 ay be a key factor in the selectivity of non-heme iron "rebound" processes.

250 r, might regulate macrophage heme export and heme iron recycling in vivo.

251 e iron, the basic mechanism(s) governing sGC heme iron recycling to its NO-sensitive, reduced state r

252 hroblast survival and facilitates macrophage heme iron recycling.

253 using tin protoporphyrin IX (SnPP) decreased heme-iron recycling in the liver and ameliorated anemia

254 rometry as a function of temperature and the heme iron redox state.

255 3 as the first identified physiological sGC heme iron reductase in vascular smooth muscle cells, ser

256 ing") route that enhances the rate of ferryl heme iron reduction by externally added reductants, for

257 The deletion of Pre-A abrogated the heme iron reduction by FdR in the HbN, thus signifying i

258 of endometrial cancer for higher intakes of heme iron (RR: 1.24; 95% CI: 1.01, 1.53 for >/=1.63 comp

259 ich it displays the IsdC protein involved in heme-iron scavenging from human hemoglobin.

260 e commonly considered to be a consequence of heme-iron serving as a nutrient for bacteria.

261 more reactive species such as .OH at the non-heme iron site in the His-cluster region formed by the a

262 dation and the successive formation of a non-heme iron site.

263 hat could be expected to form at typical non-heme iron sites in biology) are extremely rare.

264 eme detoxification and facilitates growth on heme iron sources.

265 dergoes only minor substrate binding-induced heme iron spin state shift toward high spin by compariso

266 errin saturation, but no change in liver non-heme iron stores.

267 l, but the pathways involved in distributing heme, iron-sulfur clusters, and ferrous/ferric ions to a

268 Iron cofactors include heme, iron-sulfur clusters, and simple iron ions.

269 oxygen species are known to oxidize the sGC heme iron, the basic mechanism(s) governing sGC heme iro

270 lular iron-storage protein ferritin, and for heme iron, the chaperone proteins haptoglobin and hemope

271 binding, despite extensive conversion of the heme iron to a high spin ferric state.

272 ctive site conversion" from heme iron to non-heme iron to degrade itself.

273 lexes, where one NO molecule is bound to the heme iron to form a five-coordinate low-spin {FeNO}(7) s

274 (ROS) with the "active site conversion" from heme iron to non-heme iron to degrade itself.

275 nd movement through a short channel from the heme iron to solvent that is gated by the distal histidi

276 , which has a large internal tunnel from the heme iron to the C-terminal ends of the E and H helices,

277 Here we report that reduction of the heme iron to the ferrous [Fe(II)] state in DGCR8 abolish

278 ggests a modest positive association between heme iron, total iron, and liver intakes and endometrial

279 teins, group B vitamins, minerals especially heme iron, trace elements and other bioactive compounds.

280 ical spectra consistent with low-spin ferric heme iron (type II) in contrast to 17EE, which yields a

281 All known heme-thiolate proteins ligate the heme iron using one cysteine side chain.

282 Heme-iron utilization involves HmuO, a heme oxygenase th

283 lugdunensis Isd system as being involved in heme-iron utilization.

284 ve site cavity and irreversibly binds to the heme iron via the thiazole nitrogen, which decreases the

285 operamide, and voriconazole coordinating the heme iron via their nitrogen atoms and clotrimazole bein

286 Heme iron was associated with a higher risk of T2D even

287 stal structure of inhibitor 3 coordinated to heme iron was obtained, representing, to our knowledge,

288 occus aureus, which preferentially scavenges heme iron, was unaffected.

289 ron, which has lower absorption than that of heme iron.We assessed the efficacy of the consumption of

290 ron, iron from meat, iron from red meat, and heme iron were all close to unity, and there were no inc

291 Y-shaped fluvoxamine coordinates the CYP46A1 heme iron, whereas the methoxy-containing arm points awa

292 hat intakes of processed meat, red meat, and heme iron, which characterized the Western dietary patte

293 8) and His(89) of alphaHb, coordinate to the heme iron, which is poised for transfer into the heme-bi

294 Then, they process the heme iron, which is returned to the circulation for reut

295 yl palmitate addition and co-spray-drying of heme iron with calcium caseinate.

296 spectra that are typical of a hexacoordinate heme iron with histidine and water ligands.

297 e association of intakes of dietary iron and heme iron with risk of postmenopausal breast cancer.

298 ires the replacement of the natural abundant heme iron with the (57)Fe isotope.

299 is long antifungal drug coordinates the P450 heme iron with the nitrogen atom of its terminal azole r

300 Heme-iron within hemoglobin (Hb) is the most abundant so